A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Duligotuzumab | Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting EGFR. Duligotuzumab blocks the binding of ligands to these two receptors, inhibits downstream HER/ErbB, AKT and MAPK signaling pathways, induces antibody-dependent cellular cytotoxicity, reduces the proliferation and migration abilities of cancer cells, promotes apoptosis, exerts radiosensitizing effects, and reverses EGFR resistance in cancer cells. Duligotuzumab can be used in tumor-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEHD-7945A; RG 7597. CAS No. 1314238-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99866. |  |
| Duloxetine | Duloxetine is a serotonin-norepinephrine reuptake inhibitor (Ki=4.6 nM), used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. Uses: Adrenergic uptake inhibitors; analgesics; antidepressive agents; dopamine uptake inhibitors; serotonin uptake inhibitors. Synonyms: (S)-Duloxetine; Cymbalta; Yentreve; (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine; LY 248686; Xeristar; LY248686; LY-248686; (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine. Grade: >98%. CAS No. 116539-59-4. Molecular formula: C18H19NOS. Mole weight: 297.41. |  |
| Duloxetine | Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY248686. CAS No. 116539-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0161. | |
| Duloxetine-d7 Maleate | Labeled Duloxetine, which is used as an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Group: Biochemicals. Alternative Names: (γS)-N-Methyl-γ-(1-naphthalenyloxy-d7)-2-thiophenepropanamine Maleate; (+)-(S)-N-Methyl-γ-(1-naphthyloxy-d7)-2-thiophenepropylamine Maleate; LY-248686 Maleate. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Duloxetine EP Impurity A | Duloxetine HCl R-Isomer. Uses: Analgesics. Synonyms: (3R)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine HCl. Grade: > 95%. CAS No. 910138-96-4. Molecular formula: C18H19NOS·HCl. Mole weight: 333.882. | |
| Duloxetine EP impurity B | Duloxetine EP impurity B. Uses: For analytical and research use. Alternative Names: (S)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol. CAS No. 116539-55-0. Molecular formula: C8H13NSO. Mole weight: 171.26. Catalog: APB116539550. |  |
| Duloxetine EP impurity C | Duloxetine EP impurity C. Uses: For analytical and research use. Alternative Names: 4-(3-(methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol. CAS No. 949095-98-1. Molecular formula: C18H19NSO. Mole weight: 297.41. Catalog: APB949095981. | |
| Duloxetine EP Impurity C | Duloxetine EP Impurity C. Uses: For analytical and research use. CAS No. 949096-01-9. Molecular formula: C18H20BrNOS. Mole weight: 378.33. Catalog: APB949096019. | |
| Duloxetine EP Impurity C HBr | Duloxetine Impurity. Grade: > 95%. CAS No. 949096-01-9. Molecular formula: C18H19NOS·HBr. Mole weight: 378.333. | |
| Duloxetine EP impurity E | Duloxetine EP impurity E. Uses: For analytical and research use. Alternative Names: 2-(3-(methylamino)-1-(thiophen-2-yl)propyl)naphthalen-1-ol. CAS No. 1033803-59-6. Molecular formula: C18H19NSO. Mole weight: 297.41. Catalog: APB1033803596. | |
| Duloxetine EP Impurity E | An impurity of the antidepressant Duloxetine. Synonyms: 1-(3-(Methylamino)thiophen-2-yl)propyl)naphthalen-2-ol. Grade: > 95%. CAS No. 1346599-09-4. Molecular formula: C18H19NOS. Mole weight: 297.41. | |
| Duloxetine EP Impurity F | Duloxetine EP Impurity F. Uses: For analytical and research use. Molecular formula: C18H20ClNOS. Mole weight: 333.87. Catalog: APB07644. | |
| Duloxetine EP Impurity F (Duloxetine 3-Acetyl) HCl | An isomeric impurity of the antidepressant Duloxetine. Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine Hydrochloride. Grade: > 95%. CAS No. 1104890-90-5. Molecular formula: C18H19NOS·HCl. Mole weight: 333.88. | |
| Duloxetine EP Impurity F Hydrochloride | Duloxetine EP Impurity F Hydrochloride is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride; Duloxetine Related Compound F. Grade: 98%. CAS No. 2748376-86-3. Molecular formula: C18H20ClNOS. Mole weight: 333.88. | |
| Duloxetine hydrochloride | Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (S)-Duloxetine hydrochloride; LY-248686 hydrochloride. CAS No. 136434-34-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0161A. | |
| Duloxetine hydrochloride | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C18H19NOS · HCl. CAS No. 136434-34-9. Prepack ID 60808159-1g. Molecular Weight 333.88. See USA prepack pricing. |  |
| Duloxetine hydrochloride | Duloxetine Hydrochloride is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). Synonyms: LY-248686 HCl; LY 248686 HCl; LY248686 HCl. Grade: >98%. CAS No. 136434-34-9. Molecular formula: C18H19NOS.HCl. Mole weight: 333.88. | |
| Duloxetine Hydrochloride | An antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence. Group: Biochemicals. Alternative Names: (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Hydrochloride; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine Hydrochloride; LY-248686. Grades: Highly Purified. CAS No. 136434-34-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Duloxetine Hydrochloride | Duloxetine hydrochloride is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) approved for major depressive disorder, generalized anxiety disorder, and chronic pain conditions. The drug is structurally distinct from venlafaxine and has a more balanced dual reuptake inhibition profile. Applications: Duloxetine is indicated for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal pain (including chronic low back pain and osteoarthritis pain), and stress urinary incontinence in women. it is also used off-label for chemotherapy-induced peripheral neuropathy. Category: Active pharmaceutical ingredients. Synonyms: Duloxetine HCl; Ariclaim; Duloxetine mylan; LY248686 HCl. CAS No. 136434-34-9. Product ID: API136434349. Molecular formula: C18H20ClNOS. Mole weight: 333.9. EINECS: 603-962-5. InChIKey: BFFSMCNJSOPUAY-LMOVPXPDSA-N. Appearance: White to off-white crystalline powder. |  |
| Duloxetine impurity 10 | Duloxetine impurity 10. Uses: For analytical and research use. Alternative Names: (S)-phenyl methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamate. CAS No. 947686-09-1. Molecular formula: C25H23NSO3. Mole weight: 417.52. Catalog: APB947686091. | |
| Duloxetine impurity 11 | Duloxetine impurity 11. Uses: For analytical and research use. Alternative Names: (R)-phenyl methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamate. Molecular formula: C25H23NO3S. Mole weight: 417.52. Catalog: APB04792. | |
| Duloxetine impurity 12 | Duloxetine impurity 12. Uses: For analytical and research use. Alternative Names: (S)-4-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)amino)-4-oxobutanoic acid. CAS No. 199191-66-7. Molecular formula: C22H23NO4S. Mole weight: 397.49. Catalog: APB199191667. | |
| Duloxetine impurity 13 | Duloxetine impurity 13. Uses: For analytical and research use. Alternative Names: (S)-2-(methyl(3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl)carbamoyl)benzoic acid. CAS No. 199191-67-8. Molecular formula: C26H23NO4S. Mole weight: 445.53. Catalog: APB199191678. | |
| Duloxetine impurity 14 | Duloxetine impurity 14. Uses: For analytical and research use. Alternative Names: (R)-3-(methylamino)-1-(thiophen-2-yl)propan-1-ol. CAS No. 116539-57-2. Molecular formula: C8H13NSO. Mole weight: 171.26. Catalog: APB116539572. | |
| Duloxetine impurity 15 | Duloxetine impurity 15. Uses: For analytical and research use. Alternative Names: 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride. CAS No. 5424-47-5. Molecular formula: C9H13NOS·HCl. Mole weight: 219.73. Catalog: APB5424475. | |
| Duloxetine impurity 16 | Duloxetine impurity 16. Uses: For analytical and research use. Alternative Names: 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol. CAS No. 13636-02-7. Molecular formula: C9H15NSO. Mole weight: 185.29. Catalog: APB13636027. | |
| Duloxetine impurity 17 | Duloxetine impurity 17. Uses: For analytical and research use. Alternative Names: (S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol. CAS No. 132335-44-5. Molecular formula: C9H15NSO. Mole weight: 185.29. Catalog: APB132335445. | |
| Duloxetine impurity 18 | Duloxetine impurity 18. Uses: For analytical and research use. Alternative Names: (S)-3-(dimethylamino)-1-(thiophen-3-yl)propan-1-ol. CAS No. 1384080-56-1. Molecular formula: C9H15NSO. Mole weight: 185.29. Catalog: APB1384080561. | |
| Duloxetine impurity 19 | Duloxetine impurity 19. Uses: For analytical and research use. Alternative Names: (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine. CAS No. 1384080-33-4. Molecular formula: C19H21NSO. Mole weight: 311.44. Catalog: APB1384080334. | |
| Duloxetine impurity 19 (Oxalicacid) | Duloxetine impurity 19 (Oxalicacid). Uses: For analytical and research use. Alternative Names: (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine oxalate. Molecular formula: C19H21NOS·C2H2O4. Mole weight: 401.47. Catalog: APB04791. | |
| Duloxetine impurity 20 | Duloxetine impurity 20. Uses: For analytical and research use. Alternative Names: (S)-2-(3-chloro-1-(naphthalen-1-yloxy)propyl)thiophene. CAS No. 164071-61-8. Molecular formula: C17H15ClOS. Mole weight: 302.05. Catalog: APB164071618. | |
| Duloxetine Impurity 20 | Duloxetine Impurity 20. Uses: For analytical and research use. CAS No. 116817-27-7. Molecular formula: C18H19NOS. Mole weight: 297.42. Catalog: APB116817277. | |
| Duloxetine Impurity 21 | Duloxetine Impurity 21. Uses: For analytical and research use. Alternative Names: N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine. CAS No. 116817-25-5. Molecular formula: C19H21NOS. Mole weight: 311.44. Catalog: APB116817255. | |
| Duloxetine Impurity 21 (Hydrochloride) | Duloxetine Impurity 21 (Hydrochloride). Uses: For analytical and research use. Alternative Names: N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride. Molecular formula: C19H21NOS·HCl. Mole weight: 347.9. Catalog: APB04892. | |
| Duloxetine Impurity 21 (Oxalicacid) | Duloxetine Impurity 21 (Oxalicacid). Uses: For analytical and research use. Alternative Names: N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine oxalate. CAS No. 116817-26-6. Molecular formula: C21H23NO5S. Mole weight: 401.48. Catalog: APB116817266. | |
| Duloxetine Impurity 22 | Duloxetine Impurity 22. Uses: For analytical and research use. Alternative Names: (R)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol. CAS No. 132335-49-0. Molecular formula: C9H15NOS. Mole weight: 185.29. Catalog: APB132335490. | |
| Duloxetine Impurity 22 | Duloxetine Impurity 22. Uses: For analytical and research use. CAS No. 5234-06-0. Molecular formula: C13H12O2. Mole weight: 200.23. Catalog: APB5234060. | |
| Duloxetine impurity 8 | Duloxetine impurity 8. Uses: For analytical and research use. Alternative Names: (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine. CAS No. 132335-46-7. Molecular formula: C19H21NSO. Mole weight: 311.44. Catalog: APB132335467. | |
| Duloxetine Impurity 8 (Oxalicacid) | Duloxetine Impurity 8 (Oxalicacid). Uses: For analytical and research use. Alternative Names: (S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate. CAS No. 132335-47-8. Molecular formula: C19H21NOS·C2H2O4. Mole weight: 401.48. Catalog: APB132335478. | |
| Duloxetine impurity 9 | Duloxetine impurity 9. Uses: For analytical and research use. Alternative Names: (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine. CAS No. 878757-08-5. Molecular formula: C19H21NSO. Mole weight: 311.44. Catalog: APB878757085. | |
| Duloxetine impurity 9 (Oxalate) | Duloxetine impurity 9 (Oxalate). Uses: For analytical and research use. Alternative Names: (R)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine oxalate. CAS No. 932013-45-1. Molecular formula: C21H23NO5S. Mole weight: 401.48. Catalog: APB932013451. | |
| Duloxetine impurity A | Duloxetine impurity A. Uses: For analytical and research use. Alternative Names: (R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride. CAS No. 910138-96-4. Molecular formula: C18H20ClNSO. Mole weight: 333.88. Catalog: APB910138964. | |
| Duloxetine Impurity A | A degradation product of Duloxetine. Synonyms: N-Methyl-N-[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]carbamic Acid Phenyl Ester. Grade: > 95%. CAS No. 947686-09-1. Molecular formula: C25H23NO3S. Mole weight: 417.52. | |
| Duloxetine impurity (alpha-hydroxy) | Duloxetine impurity. Grade: > 95%. CAS No. 940291-11-2. Molecular formula: C18H19NOS. Mole weight: 297.42. | |
| Duloxetine impurity D | Duloxetine impurity D. Uses: For analytical and research use. Alternative Names: naphthalen-1-ol. CAS No. 90-15-3. Molecular formula: C10H8O. Mole weight: 144.17. Catalog: APB90153. | |
| Duloxetine impurity F | Duloxetine impurity F. Uses: For analytical and research use. Alternative Names: (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine hydrochloride. CAS No. 959392-22-4. Molecular formula: C18H20ClNSO. Mole weight: 333.88. Catalog: APB959392224. | |
| Duloxetine impurity G | Duloxetine impurity G. Uses: For analytical and research use. Alternative Names: 1-fluoronaphthalene. CAS No. 321-38-0. Molecular formula: C10H7F. Mole weight: 146.16. Catalog: APB321380. | |
| Duloxetine Maleate | Duloxetine Maleate is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Maleate; (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine Maleate; LY-248686 Maleate; (S)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine (Z)-2-Butenedioate; (3S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)-1-propanamine (2Z)-2-butenedioate (1:1); 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1). Grade: ≥95%. CAS No. 116817-86-8. Molecular formula: C22H23NO5S. Mole weight: 413.49. | |
| Duloxetine N-methyl Impurity | A duloxetine impurity. Synonyms: (S)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine Ethanedioate; (γS)-N,N-Dimethyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Ethanedioate. Grade: > 95%. CAS No. 132335-47-8. Molecular formula: C19H21NOS·C2H2O4. Mole weight: 401.48. | |
| Duloxetine Related Compound H | Duloxetine Related Compound H is an impurity of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and central sensitization. Synonyms: (S)-Duloxetine Succinamide; 4-[Methyl[(3S)-3-(1-naphthalenyloxy)-3-(2-thienyl)propyl]amino]-4-oxobutanoic Acid. Grade: 98%. CAS No. 199191-66-7. Molecular formula: C22H23NO4S. Mole weight: 397.49. | |
| Dulse Seaweed Powder (Palmaria palmata) (Whole Plant) | Dulse Seaweed Powder (Palmaria palmata) (Whole Plant). Categories: furaltadone hydrochloride; furaltadone hcl. |  CA, FL & NJ |
| Dunaimycin A1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Synonyms: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11-trihydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione; 10-Deoxy-Dunaimycin C1. CAS No. 140221-72-3. Molecular formula: C42H72O9. Mole weight: 721.02. | |
| Dunaimycin C1 | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It's an immunosuppressant. Synonyms: (4E,18E)-3',4',5',6'-Tetrahydro-7,9,11,12-tetrahydroxy-6'-(2-hydroxybutyl)-5',6,8,12,27-pentamethyl-20-(2-methylpropyl)spiro[2,24-dioxabicyclo[21.3.1]heptacosa-4,18-diene-25,2'-[2H]pyran]-3,21-dione. CAS No. 140221-73-4. Molecular formula: C42H72O10. Mole weight: 737.02. | |
| Dunaimycin D4S | It is produced by the strain of Streptomyces diastatochromogenes AB 1691Q-321 and AB 1711J-452. It has weak anti-bacterial and anti-aspergillus Niger activity, and shows immunosuppressive effect in the mouse popliteal node model. CAS No. 140221-79-0. Molecular formula: C51H89NO14. Mole weight: 940.25. | |
| Dunaliella Salina P.E. 7.5% Carotenoids HPLC | Dunaliella Salina P.E. 7.5% Carotenoids HPLC. | CA, FL & NJ |
| Dunnianol | Dunnianol isolated from the fruits of Illicium fargesii. Synonyms: 5,5',5''-Triallyl-1,1':3',1''-terphenyl-2,2',2''-triol; Dunnial. Grade: 98%. CAS No. 139726-29-7. Molecular formula: C27H26O3. Mole weight: 398.5. | |
| Duocarmycin A | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has strong antibacterial and antitumor activity. It can inhibit gram-positive bacteria such as Staphylococcus aureus and Streptococcus faecalis (MIC is less than 0.01 μg/mL), it can also inhibit klebsiella pneumoniae (MIC is 0.032 μg/mL), other bacteria and yeast (MIC is 1-10 μg/mL). Synonyms: Antibiotic DC 88A; methyl (6R,7bR,8aS)-6-methyl-4,7-dioxo-2-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-1,2,4,5,6,7,8,8a-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylate; Methyl (2R,3bR,4aS)-2-methyl-3,8-dioxo-6-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-1,2,3,4,4a,5,6,8-octahydrocyclopropa[c]pyrrolo[3,2-e]indole-2-carboxylate; DUMA; (+)-Dunnione; (+)-duocarmycin A. Grade: ≥95%. CAS No. 118292-34-5. Molecular formula: C26H25N3O8. Mole weight: 507.49. | |
| Duocarmycin analog | Duocarmycin analog has cytotoxicity for solid tumor cells that can be used for antibody-drug conjugates (ADCs). Duocarmycins and the analogs acts via binding to the minor groove of DNA and alkylating the nucleobase adenine at the N3 position, which leads to DNA damage and cancer cell death. | |
| Duocarmycin B1 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-gram-positive bacteria, gram-negative bacteria and tumor activity. Synonyms: Antibiotic DC 89B1; 1H-Pyrrolo3,2-fquinoline-2-carboxylic acid, 8-bromo-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-; Duocarmycin B(sub 1). Grade: ≥95%. CAS No. 124325-93-5. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Duocarmycin B2 | It is produced by the strain of (Pyridamycin) Streptomyces sp. DO-88. It has anti-tumor activity. Synonyms: DUMB2; Benzo1,2-b:4,3-bdipyrrole-2-carboxylic acid, 8-(bromomethyl)-1,2,3,6,7,8-hexahydro-4-hydroxy-2-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl-, methyl ester, (2R,8S)-. CAS No. 124325-94-6. Molecular formula: C26H26BrN3O8. Mole weight: 588.40. | |
| Duocarmycin DM | Duocarmycin DM is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Synonyms: (S)-(1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl)(5-(2-(dimethylamino)ethoxy)-1H-indol-2-yl)methanone TFA. Grade: 95%. Molecular formula: C28H27ClF3N3O5. Mole weight: 577.98. | |
| Duocarmycin DM free base | Duocarmycin DM free base is a DNA minor-groove alkylating agent, which can be used as an antibody drug conjugate (ADC) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Synonyms: [(1S)-1-(Chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]{5-[2-(dimethylamino)ethoxy]-1H-indol-2-yl}methanone; Methanone, [(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl][5-[2-(dimethylamino)ethoxy]-1H-indol-2-yl]-. Grade: ≥97%. CAS No. 1116745-06-2. Molecular formula: C26H26ClN3O3. Mole weight: 463.96. | |
| Duocarmycin DM free base | Duocarmycin DM free base, a DNA minor-groove alkylator, is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1116745-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128915. | |
| Duocarmycin MB | Duocarmycin MB is an antibody drug conjugate (ADC) toxin that can be used against multidrug resistant cell lines. Duocarmycin is a DNA alkylating agent that binds in minor groove. Synonyms: Carbamic acid, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-6-yl]carbamate; 2-Methyl-2-propanyl (2-{[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]carbonyl}-1H-indol-6-yl)carbamate. Grade: ≥95%. CAS No. 1613286-58-0. Molecular formula: C27H26ClN3O4. Mole weight: 491.97. | |
| Duocarmycin SA | Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM[1]. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 130288-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12456. | |
| Duocarmycin TM | Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic. Duocarmycin TM induces a sequence-selective alkylation of duplex DNA. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBI-TMI. CAS No. 157922-77-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107769. | |
| Duolite a-7 ion-exchange resin | Duolite a-7 ion-exchange resin. CAS No. 32610-77-8. Molecular formula: C13H26N4O2. Mole weight: 270.37g/mol. IUPAC Name: N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;formaldehyde;phenol. SMILES: C=O.C1=CC=C(C=C1)O.C(CNCCNCCN)N. InChI: InChI=1S/C6H18N4.C6H6O.CH2O/c7-1-3-9-5-6-10-4-2-8;7-6-4-2-1-3-5-6;1-2/h9-10H,1-8H2;1-5,7H;1H2. |  |
| duolite c-26 ion-exchange resin | duolite c-26 ion-exchange resin. CAS No. 68441-33-8. | |
| Duostatin 5 | Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2124210-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145149. | |
| Duoxitasai Liposome | Duoxitasai is a paclitaxel derivative with 2 times the affinity and 10 times the activity of paclitaxel, with broad-spectrum antitumor effects. This product is a PEGylated pre-formulated liposome with duoxitasai. It is only for research purposes. Group: Drug-loaded liposome. |  |
Our database is helping our users find suppliers everyday.
