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| Product | Description | |
|---|---|---|
| D-(+)-Sucrose | 1kg Pack Size. Group: Carbohydrates, Sugars. Formula: C12H22O11. CAS No. 57-50-1. Prepack ID 90005036-1kg. Molecular Weight 342.3. See USA prepack pricing. |  |
| D-(+)-Sucrose ACS Reagent | 1kg Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: C12H22O11. CAS No. 57-50-1. Prepack ID 90028177-1kg. Molecular Weight 342.3. See USA prepack pricing. | |
| D-(+)-Sucrose, plant cell culture tested | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: C12H22O11. CAS No. 57-50-1. Prepack ID 41080463-100g. Molecular Weight 342.3. See USA prepack pricing. | |
| D-(+)-Sucrose, plant cell culture tested | 500g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: C12H22O11. CAS No. 57-50-1. Prepack ID 41080463-500g. Molecular Weight 342.3. See USA prepack pricing. | |
| DT-061 | DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809427-19-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-112929. |  |
| DT-061 | DT-061 is orally bioavailable activator of protein phosphatase 2A (PP2A). PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Synonyms: SMAP. CAS No. 1809427-19-7. Molecular formula: C25H23F3N2O5S. Mole weight: 520.52. |  |
| DT2216 | DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets. DT2216 is composed of the Bcl-2 family protein inhibitor Navitoclax-piperazine (HY-44432), a linker, and a VHL E3 ubiquitin ligase (Pink: Navitoclax-piperazine; Blue: VHL ligand; Black: linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2365172-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130604. | |
| dT-3'-PS Phosphoramidite | dT-3'-PS Phosphoramidite is a thymidine-derived phosphoramidite used for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The phosphorothioate modification replaces a non-bridging oxygen atom in the phosphate backbone with a sulfur atom, enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The thymine base is unmodified, ensuring normal base pairing during hybridization. This phosphoramidite is particularly valuable in therapeutic applications, such as antisense oligonucleotides and siRNA, where improved stability, enhanced pharmacokinetics, and resistance to enzymatic degradation are critical for effective performance. Synonyms: dT ThioPhosphamidite; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-DMT-dT-3'-PS-Phosphoramidite. Grade: ≥90%. CAS No. 178272-24-7. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97. | |
| dTAG-13 | dTAG-13(FKBP12 PROTAC dTAG-13) is an ortho-substituted, heterobifunctional selective degrader of FKBP12F36V that effectively engage FKBP12F36V and CRBN leading to rapid and selective CRBN-mediated degradation of FKBP12F36V.It can useful for target validation in the context of drug discovery. Group: Inhibitors. Alternative Names: FKBP12 PROTAC dTAG-13. CAS No. 2064175-41-1. Pack Sizes: 5mg. Product ID: S9813. Formula: C57H68N4O15. |  United States; Europe |
| dTAG-13-NEG | dTAG-13-NEG is a negative control of dTAG-13 (HY-114421). dTAG-13, a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2451573-90-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-161157. | |
| dTAG-47 | dTAG-47 is a FKBP12F36V PROTAC degrader. dTAG-47 efficiently degrades FKBP12F36V-MELK(sg3R) in MELK?/? MDA-MB-468-FKBP12F36V-MELK(sg3R) cells. dTAG-47 can be used for the research of basal-like breast cancers (BBC). (Pink: FKBP12F36V ligand (HY-114420), Blue: CRBN Ligand (HY-W087383), Black: Linker (HY-42773), E3 ligase ligand-linker conjugate (HY-175952))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2265886-81-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147098. | |
| D-Tagatose | 25g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C6H12O6. CAS No. 87-81-0. Prepack ID 41068941-25g. Molecular Weight 180.16. See USA prepack pricing. | |
| D-Tagatose-[1-13C] | A labelled analogue of D-Tagatose. D-Tagatose is a monosaccharide which is used as a low-calorie sweetener, as an intermediate for synthesis of other optically active compounds, and as an additive in detergent, cosmetic, and pharmaceutical formulation. Synonyms: D-lyxo-2-Hexulose-1-13C; D-[1-13C]Tagatose. CAS No. 478506-42-2. Molecular formula: C5[13C]H12O6. Mole weight: 180.16. | |
| D-Tagatose 1-phosphate | D-Tagatose 1-phosphate is a multifunctional compound for studying viral infections. It has exhibited its prowess as a pivotal intermediate in the synthesis of versatile chemical compounds, including potent antiviral compounds. CAS No. 63323-90-0. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| D-Tagatose-[2-13C] | A labelled analogue of D-Tagatose. D-Tagatose is a monosaccharide which is used as a low-calorie sweetener, as an intermediate for synthesis of other optically active compounds, and as an additive in detergent, cosmetic, and pharmaceutical formulation. Synonyms: D-lyxo-2-Hexulose-2-13C; D-[2-13C]Tagatose. CAS No. 478506-44-4. Molecular formula: C5[13C]H12O6. Mole weight: 181.15. | |
| D-tagatose 3-epimerase | The enzymes isolated from the bacteria Pseudomonas cichorii, Pseudomonas sp. ST-24, Rhodobacter sphaeroides and Mesorhizobium loti catalyse the epimerization of various ketoses at the C-3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose. The specificity depends on the species. The enzymes from Pseudomonas cichorii and Rhodobacter sphaeroides require Mn2+. Group: Enzymes. Synonyms: L-ribulose 3-epimerase; ketose 3-epimerase. Enzyme Commission Number: EC 5.1.3.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5418; D-tagatose 3-epimerase; EC 5.1.3.31; L-ribulose 3-epimerase; ketose 3-epimerase. Cat No: EXWM-5418. |  |
| D-Tagatose-6-phosphate | D-Tagatose-6-phosphate is a remarkable compound, acting as a potent suppressor of carbohydrate metabolism-associated enzymes for diabetes research. Synonyms: D-Tagatofuranose 6-phosphate. CAS No. 67424-99-1. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| D-Tagatose-6-phosphate barium salt | D-Tagatose-6-phosphate barium salt. Molecular formula: C6H11BaO9P. Mole weight: 395.45. | |
| D-Tagatose-6-phosphate lithium salt | D-Tagatose-6-phosphate lithium salt is a bacterial strain that belongs to the group of polyols. D-Tagatose 6-phosphate is a substrate for tagatose-6-phosphate kinase which converts it into D-tagatose 1,6-bisphosphate with the transfer of a phosphate from ATP. Synonyms: D-Tagatofuranose 6-phosphate lithium salt. CAS No. 73544-42-0. Molecular formula: C6H13O9P.xLi. Mole weight: 260.14 (free acid). | |
| D-tagatose-[UL-13C6] | A labelled analogue of D-Tagatose. D-Tagatose is a monosaccharide which is used as a low-calorie sweetener, as an intermediate for synthesis of other optically active compounds, and as an additive in detergent, cosmetic, and pharmaceutical formulation. Synonyms: D-[UL-13C6]tagatose; D-tagatose-U-13C6. Molecular formula: [13C]6H12O6. Mole weight: 186.11. | |
| dTAGV-1 | dTAGV-1 is a potent and selective degrader of FKBP12F36V-tagged proteins PROTAC degrader. dTAGV-1 can induce degradation of FKBP12F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2451573-86-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145514D. | |
| dTAGV-1 hydrochloride | dTAGV-1 hydrochloride is a potent and selective degrader of FKBP12F36V-tagged proteins PROTAC degrader. dTAGV-1 hydrochloride can induce degradation of FKBP12F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2624313-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145514C. | |
| dTAGV-1-NEG | dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2451573-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-145514A. | |
| dTAGV-1 TFA | dTAGV-1 TFA is a potent and selective degrader of FKBP12F36V-tagged proteins PROTAC degrader. dTAGV-1 TFA can induce degradation of FKBP12F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2624313-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145514. | |
| D-Talitol | D-Talitol, a remarkably versatile sugar alcohol, finds extensive application as an excipient in diverse pharmaceutical formulations. Renowned for its profound efficacy in augmenting the flavor of oral drugs, it frequently serves as an agent to enhance the taste of chewable tablets and syrups to facilitate greater palatability. Moreover, D-Talitol assumes a pivotal role in the synthetic fabrication of numerous bioactive compounds, thereby showcasing its indispensable role in combating an assortment of diseases. Synonyms: D-Altritol. CAS No. 643-03-8. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| D-Talitol-1,6-diphosphate | D-Talitol-1,6-diphosphate. | |
| D-Talono-1,4-lactone | D-Talono-1,4-lactone is an indispensable compound for the research of Alzheimer's, Parkinson's and diverse neurodegenerative maladies, intricately operating as a neuroactivity modifier. Synonyms: gamma-D-Galactonolactone; Gulono-1,4-lactone; D-Allonic acid gamma-lactone; D-Idonic acid, gamma-lactone; D-Galactonic acid, gamma-lactone; 5-(1,2-Dihydroxy-ethyl)-3,4-dihydroxy-dihydro-furan-2-one; gamma-Lactone of mannonic acid; D-Mannonic acid, gamma-lactone; D-Galactonic acid, gamma-lactone; 1,4-D-Gulonolactone; D-Allono-1,4-lactone; L-Gulonic acid g-lactone; Gulonic acid-1,4-lactone; D-Gulonic acid-1,4-lactone; Mannonic acid, D-; Galactonic acid, D-; glucono-1,4-lactone; 1,4-D-Mannonolactone; D-Galactono-gamma-lactone. CAS No. 23666-11-7. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| D-Talose | D-Talose, a pivotal ingredient within the biomedical sphere, showcases its exceptional value in combating an array of ailments, including diabetes and cancer. Recognized for its medicinal prowess, this extensively examined compound exhibits captivating potential in pharmaceutical progress and the amelioration of maladies. Presenting a broad scope of applications, D-Talose stands as an indispensable force propelling biomedical exploration while simultaneously heightening the likelihood of positive prognoses for patients. Synonyms: D-(+)-Talose; aldehydo-D-talose; (2S,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal; 8ZW23G7NVD; NSC-224293; EINECS 219-996-5; TALOSE, D-; UNII-8ZW23G7NVD; SCHEMBL37336; CHEBI:68461; GZCGUPFRVQAUEE-KAZBKCHUSA-N; DTXSID701318243; GEO-04668; MFCD00135834; AKOS024256927; HY-W145492; NSC 224293; CS-0214426; T72182; A877420; Q423195; W-202099; A02CA752-AB99-4BBF-84BA-31F5846CA891. CAS No. 2595-98-4. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| D-Talose | 100mg Pack Size. Group: Biochemicals, Carbohydrates. Formula: C6H12O6. CAS No. 2595-98-4. Prepack ID 41482505-100mg. Molecular Weight 180.16. See USA prepack pricing. | |
| D-talose-[1-13C] | D-talose-[1-13C]. Synonyms: D(+)-Talose-13C; NSC 224293-13C; D-[1-13C]talose. CAS No. 70849-29-5. Molecular formula: C5[13C]H12O6. Mole weight: 181.15. | |
| D-talose-[1-13C,1-d] | D-talose-[1-13C,1-d]. Synonyms: D-[1-13C,1-2H]talose; D-talose-1-13C,1-d; D-[1-13C,1-D]talose. Molecular formula: C5[13C]H11DO6. Mole weight: 182.16. | |
| D-talose-[1,2-13C2] | D-talose-[1,2-13C2] is a labelled analogue of D-talose which is a C-2 epimer of galactose. D-talose has been used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) of Clostridia. Synonyms: D-[1,2-13C2]talose; D-talose-1,2-13C2. Molecular formula: C4[13C]2H12O6. Mole weight: 182.14. | |
| D-talose-[1,2,3-13C3] | D-talose-[1,2,3-13C3] is a labelled analogue of D-talose which is a C-2 epimer of galactose. D-talose has been used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) of Clostridia. Synonyms: D-[1,2,3-13C3]talose; D-talose-1,2,3-13C3. Molecular formula: C3[13C]3H12O6. Mole weight: 183.13. | |
| D-Talose-1-d1 | D-Talose-1-d1. Group: Biochemicals. Alternative Names: D(+)-Talose-1-d1; NSC 224293-1-d1. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C6DH11O6, Molecular Weight: 181.16. US Biological Life Sciences. |  Worldwide |
| D-talose-[2-13C] | D-talose-[2-13C]. Synonyms: D-talose 2-13C. Grade: 95% by CP; 99% atom 13C. CAS No. 83379-36-6. Molecular formula: C5[13C]H12O6. Mole weight: 181.15. | |
| D-talose-[4-13C] | D-talose-[4-13C] is a labelled analogue of D-talose which is a C-2 epimer of galactose. D-talose has been used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) of Clostridia. Synonyms: D-[4-13C]talose; D-talose-4-13C. Molecular formula: C5[13C]H12O6. Mole weight: 181.15. | |
| D-talose-[UL-13C6] | D-talose-[UL-13C6] is a labelled analogue of D-talose which is a C-2 epimer of galactose. D-talose has been used as a substrate to identify, differentiate and characterize ribose-5-phosphate isomerase(s) of Clostridia. Synonyms: D-[UL-13C6]talose; D-talose-U-13C6. Molecular formula: [13C]6H12O6. Mole weight: 186.11. | |
| D-(-)-Tartaric acid | D-(-)-Tartaric acid. Alternative Names: (2S,3S)-(-)-Tartaric acid. CAS No. 147-71-7. Purity: >99.0%. Product ID: FFC-AR-147717. Molecular formula: C4H6O6. Mole weight: 150.09. IUPAC Name: (2S,3S)-2,3-dihydroxybutanedioic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| D-Tartaric acid | D-Tartaric acid. Synonyms: d-tartaric;tartaricacidd-minus;Tartarieacid;(S,S)-TARTARIC ACID;TARTARIC ACID;TARTARIC ACID, D-(-)-;TARTARIC ACID [DEXTRO (+)];TARTARIC ACID UNNATURAL. CAS No. 147-71-7. Pack Sizes: 1 kg. Product ID: CDF4-0001. Molecular formula: C4H6O6. Category: Acidity Regulators. Product Keywords: Food Ingredients; Acidity Regulators; D-Tartaric acid; CDF4-0001; 147-71-7; C4H6O6; 205-695-6; 147-71-7. Purity: 0.99. Color: White. EC Number: 205-695-6. Physical State: Crystals or Crystalline Powder. Solubility: water: soluble100mg/mL, clear, colorless. Storage: Store below 30°C. Boiling Point: 191.59°C (rough estimate). Melting Point: 172-174 °C(lit.). Density: 1.8 g/cm3. |  |
| D-Tartaric acid | D-Tartaric acid. Synonyms: d-tartaric;tartaricacidd-minus;Tartarieacid;(S,S)-TARTARIC ACID;TARTARIC ACID;TARTARIC ACID, D-(-)-;TARTARIC ACID [DEXTRO (+)];TARTARIC ACID UNNATURAL. CAS No. 147-71-7. Product ID: PE-0273. Molecular formula: C4H6O6. Category: Ointment Base. Product Keywords: Pharmaceutical Excipients; Semi-solid Dosage Form; Ointment Base; D-Tartaric acid; PE-0273; C4H6O6; 147-71-7; 147-71-7. Purity: 0.99. Color: White. EC Number: 205-695-6. Physical State: Crystals or Crystalline Powder. Solubility: water: soluble100mg/mL, clear, colorless. Storage: Store below 30°C. Boiling Point: 191.59°C (rough estimate). Melting Point: 172-174 °C(lit.). Density: 1.8 g/cm3. | |
| D-Tartaric acid | D-Tartaric acid. CAS No. 141-71-7. Product ID: ACM141717. Alfa Chemistry - ISO 9001:32057 Certified. | |
| D(-)Tartaric acid | D(-)Tartaric acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 147-71-7. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C4H6O6. US Biological Life Sciences. | Worldwide |
| D-(-)-Tartaric Acid | D-(-)-Tartaric Acid the synthetic enantiomer of L-(+)-Tartaric Acid (T007630), used in the preparation of synthetic analgesics. Group: Biochemicals. Alternative Names: (2S,3S)-2,3-Dihydroxybutanedioic Acid; [S-(R*,R*)]-2,3-Dihydroxybutanedioic Acid; (-)-Tartaric Acid; (2S,3S)-(-)-Tartaric Acid; (2S,3S)-2,3-Dihydroxysuccinic Acid; (2S,3S)-Tartaric Acid; (S,S)-(-)-Tartaric Acid; (S,S)-Tartaric Acid; D-(-)-Tartaric Acid; D-Tartaric Acid; l-Tartaric Acid; levo-Tartaric Acid. Grades: Highly Purified. CAS No. 147-71-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| D(-)-tartrate dehydratase | Requires Fe2+ or Mn2+. cf. EC 4.2.1.32 L(+)-tartrate dehydratase. Group: Enzymes. Synonyms: D-tartrate dehydratase; (S,S)-tartrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.81. CAS No. 82532-88-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5066; D(-)-tartrate dehydratase; EC 4.2.1.81; 82532-88-5; D-tartrate dehydratase; (S,S)-tartrate hydro-lyase. Cat No: EXWM-5066. | |
| D-TAT (47-57) | D-TAT (47-57) is a cell-penetrating peptide composed of D-amino acid residues 48 to 57 fragment of the basic domain of HIV Tat. Synonyms: H-D-Tyr-D-Gly-D-Arg-D-Lys-D-Lys-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Arg-NH2. Grade: ≥90% by HPLC. Molecular formula: C64H119N33O13. Mole weight: 1558.87. | |
| DTBPA | DTBPA. CAS No. 37434-06-3. Pack Sizes: Milligram Quantities: 100 mg. Order Number: PA118. |  www.prochemonline.com |
| DTBS-Gemcitabine | A derivative of Gemcitabine. Gemcitabine is a nucleoside analog used in chemotherapy to treat cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Synonyms: 2'-Deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-2',2'-difluorocytidine; 4-Amino-1-((2R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)-3,3-difluorotetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 3',5'-Bis-O-tert-butyldimethylsilyl-2'-deoxy-2',2'-difluorocytidine. Grade: ≥95%. CAS No. 688009-09-8. Molecular formula: C21H39N3O4F2Si2. Mole weight: 491.72. | |
| DTCBPy | DTCBPy. CAS No. 1850369-76-4. Molecular formula: C52H55N3O. Mole weight: 738g/mol. IUPAC Name: [2,5-bis(3,6-ditert-butylcarbazol-9-yl)phenyl]-pyridin-4-ylmethanone. SMILES: CC(C)(C)C1=CC2=C(C=C1)N(C3=C2C=C(C=C3)C(C)(C)C)C4=CC(=C(C=C4)N5C6=C(C=C(C=C6)C(C)(C)C)C7=C5C=CC(=C7)C(C)(C)C)C(=O)C8=CC=NC=C8. InChI: InChI=1S/C52H55N3O/c1-49(2,3)33-13-18-43-38(27-33)39-28-34(50(4,5)6)14-19-44(39)54(43)37-17-22-47(42(31-37)48(56)32-23-25-53-26-24-32)55-45-20-15-35(51(7,8)9)29-40(45)41-30-36(52(10,11)12)16-21-46(41)55/h13-31H,1-12H3. |  |
| DT Diaphorase from human, Recombinant | DT Diaphorase is a flavoenzyme that catalyzes the oxidation of reduced di-and triphosphopyridine nucleotides. It contains one mole of FAD per mole of enzyme. The enzyme found in rat liver catalyzes the oxidation of NADH and NADPH by various dyes and quinones. The molecular weight is found to be approximately 48 kDa Da. The pH optimum of the enzyme purified from rat liver is found to be 5.0. It is a cytosolic enzyme that catalyzes the two-electron reduction of various quinones. It catalyzes the conversion of vitamin K to vitamin K hydroquinone for utilization in the post-translational γ-glutamyl carboxylation reactions. These reactions are necessary for several proteins involved in blood coagulation. Applications: Human dt diaphorase has been used in a study to assess the development of novel quinone phosphorodiamidate prodrugs. human dt diaphorase has also been used to investigate its crystal structure for the development of a model for its interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (cb1954). Group: Enzymes. Synonyms: menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD (P)H-q. Enzyme Commission Number: EC 1.6.99.2. Diaphorase. Mole weight: monomer mol wt 31 kDa. Storage: 2-8°C. F. | |
| DT Diaphorase from rat, Recombinant | DT Diaphorase is a flavoenzyme that catalyzes the oxidation of reduced di-and triphosphopyridine nucleotides. It contains one mole of FAD per mole of enzyme. The enzyme found in rat liver catalyzes the oxidation of NADH and NADPH by various dyes and quinones. The molecular weight is found to be approximately 48 kDa Da. The pH optimum of the enzyme purified from rat liver is found to be 5.0. It is a cytosolic enzyme that catalyzes the two-electron reduction of various quinones. It catalyzes the conversion of vitamin K to vitamin K hydroquinone for utilization in the post-translational γ-glutamyl carboxylation reactions. These reactions are necessary for several proteins involved in blood coagulation. Applications: Dt diaphorase from rat has been used in a study to investigate the two-electron reduction of quinones by rat liver. dt diaphorase from rat has also been used in a study to investigate colon cancer chemopreventive efficacy of silibinin through perturbation of xenobiotic metabolizing enzymes. Group: Enzymes. Synonyms: menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD (P)H-qui. Enzyme Commission Number: EC 1.6.99.2. Purity: ~90% (SDS-PAGE). Diaphorase. Mole weight: monomer mol wt 31 kDa. Storage: 2-8°C. Form. | |
| dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase | The enzyme is involved in the biosynthesis of several deoxysugars, including L-digitoxose, L- and D-olivose, L-oliose, D-mycarose and forosamine. Group: Enzymes. Synonyms: KijD10; dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase; dTDP-4-dehydro-2,6-dideoxy-α-D-glucose 3-oxidoreductase. Enzyme Commission Number: EC 1.1.1.384. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0303; dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase; EC 1.1.1.384; KijD10; dTDP-4-keto-2,6-dideoxy-D-glucose 3-oxidoreductase; dTDP-4-dehydro-2,6-dideoxy-α-D-glucose 3-oxidoreductase. Cat No: EXWM-0303. | |
| dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase | The enzyme is involved in the biosynthesis of several deoxysugars, including L-digitoxose, L- and D-olivose, L-oliose, D-mycarose and forosamine. | |
| dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase | The enzyme is involved in the biosynthesis of desosamine, a 3-(dimethylamino)-3,4,6-trideoxyhexose found in certain macrolide antibiotics such as erthyromycin, azithromycin, and clarithromycin. | |
| dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase | The enzyme is involved in the biosynthesis of desosamine, a 3-(dimethylamino)-3,4,6-trideoxyhexose found in certain macrolide antibiotics such as erthyromycin, azithromycin, and clarithromycin. Group: Enzymes. Synonyms: DesVI. Enzyme Commission Number: EC 2.1.1.234. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1837; dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase; EC 2.1.1.234; DesVI. Cat No: EXWM-1837. | |
| dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase | A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-α-D-desosamine, a sugar found in several bacterial macrolide antibiotics including erythromycin, megalomicin A, mycinamicin II, and oleandomycin. The reaction occurs in the reverse direction. | |
| dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase | A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-α-D-desosamine, a sugar found in several bacterial macrolide antibiotics including erythromycin, megalomicin A, mycinamicin II, and oleandomycin. The reaction occurs in the reverse direction. Group: Enzymes. Synonyms: desV (gene name); megDII (gene name); eryCI (gene name). Enzyme Commission Number: EC 2.6.1.106. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2846; dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase; EC 2.6.1.106; desV (gene name); megDII (gene name); eryCI (gene name). Cat No: EXWM-2846. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose 3-N-acetyltransferase | The product, dTDP-3-acetamido-3,6-dideoxy-α-D-galactose, is a component of the glycan chain of the crystalline bacterial cell surface layer protein (S-layer glycoprotein) of Aneurinibacillus thermoaerophilus. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose 3-N-acetyltransferase | The product, dTDP-3-acetamido-3,6-dideoxy-α-D-galactose, is a component of the glycan chain of the crystalline bacterial cell surface layer protein (S-layer glycoprotein) of Aneurinibacillus thermoaerophilus. Group: Enzymes. Synonyms: FdtC; dTDP-D-Fucp3N acetylase. Enzyme Commission Number: EC 2.3.1.197. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2140; dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose 3-N-acetyltransferase; EC 2.3.1.197; FdtC; dTDP-D-Fucp3N acetylase. Cat No: EXWM-2140. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase | The enzyme is involved in the synthesis of dTDP-D-ravidosamine, the amino sugar moiety of the antibiotic ravidomycin V, which is produced by the bacterium Streptomyces ravidus. Group: Enzymes. Synonyms: RavNMT. Enzyme Commission Number: EC 2.1.1.236. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1839; dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase; EC 2.1.1.236; RavNMT. Cat No: EXWM-1839. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose N,N-dimethyltransferase | The enzyme is involved in the synthesis of dTDP-D-ravidosamine, the amino sugar moiety of the antibiotic ravidomycin V, which is produced by the bacterium Streptomyces ravidus. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase | A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α-D-galactose. The reaction occurs in the reverse direction. Group: Enzymes. Synonyms: dTDP-6-deoxy-D-xylohex-3-uloseaminase; FdtB; TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase; RavAMT; TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase; TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase. Enzyme Commission Number: EC 2.6.1.90. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2932; dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase; EC 2.6.1.90; dTDP-6-deoxy-D-xylohex-3-uloseaminase; FdtB; TDP-3-keto-6-deoxy-D-galactose-3-aminotransferase; RavAMT; TDP-3-keto-6-deoxy-D-galactose 3-aminotransferase; TDP-3-dehydro-6-deoxy-D-galactose 3-aminotransferase. Cat No: EXWM-2932. | |
| dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose transaminase | A pyridoxal-phosphate protein. The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-α-D-galactose. The reaction occurs in the reverse direction. | |
| dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase | The enzyme is involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin, which is produced by the bacterium Streptomyces fradiae. Group: Enzymes. Synonyms: TylM1. Enzyme Commission Number: EC 2.1.1.235. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1838; dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase; EC 2.1.1.235; TylM1. Cat No: EXWM-1838. | |
| dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose N,N-dimethyltransferase | The enzyme is involved in the biosynthesis of mycaminose, an essential structural component of the macrolide antibiotic tylosin, which is produced by the bacterium Streptomyces fradiae. | |
| dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase | A pyridoxal-phosphate protein. The reaction occurs in the reverse direction. The enzyme is involved in biosynthesis of D-mycaminose. Group: Enzymes. Synonyms: TylB; TDP-3-keto-6-deoxy-D-glucose 3-aminotransferase; TDP-3-dehydro-6-deoxy-D-glucose 3-aminotransferase; dTDP-3-keto-6-deoxy-D-glucose 3-aminotransferase; dTDP-3-dehydro-6-deoxy-D-glucose 3-aminotransferase. Enzyme Commission Number: EC 2.6.1.89. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2930; dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase; EC 2.6.1.89; TylB; TDP-3-keto-6-deoxy-D-glucose 3-aminotransferase; TDP-3-dehydro-6-deoxy-D-glucose 3-aminotransferase; dTDP-3-keto-6-deoxy-D-glucose 3-aminotransferase; dTDP-3-dehydro-6-deoxy-D-glucose 3-aminotransferase. Cat No: EXWM-2930. | |
| dTDP-3-amino-3,6-dideoxy-α-D-glucopyranose transaminase | A pyridoxal-phosphate protein. The reaction occurs in the reverse direction. The enzyme is involved in biosynthesis of D-mycaminose. | |
| dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase | The enzyme was isolated from the bacterium Saccharopolyspora spinosa, where it is involved in the biosynthesis of spinosyn A, an active ingredient of several commercial insecticides. Group: Enzymes. Synonyms: SpnS; TDP-4-amino-2,3,6-trideoxy-D-glucose N,N-dimethyltransferase. Enzyme Commission Number: EC 2.1.1.324. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1932; dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase; EC 2.1.1.324; SpnS; TDP-4-amino-2,3,6-trideoxy-D-glucose N,N-dimethyltransferase. Cat No: EXWM-1932. | |
| dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase | The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of enterobacterial common antigen (ECA). Group: Enzymes. Synonyms: TDP-fucosamine acetyltransferase; WecD; RffC. Enzyme Commission Number: EC 2.3.1.210. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2156; dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase; EC 2.3.1.210; TDP-fucosamine acetyltransferase; WecD; RffC. Cat No: EXWM-2156. | |
| dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase | The non-activated product, 4-acetamido-4,6-dideoxy-α-D-glucose, is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7. Group: Enzymes. Synonyms: VioB. Enzyme Commission Number: EC 2.3.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2154; dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase; EC 2.3.1.209; VioB. Cat No: EXWM-2154. | |
| dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase | The enzyme, which is a member of the 'AdoMet radical' (radical SAM) family, is involved in biosynthesis of TDP-α-D-desosamine. The reaction starts by the transfer of an electron from the reduced form of the enzyme's [4Fe-4S] cluster to S-adenosyl-L-methionine, spliting it into methionine and the radical 5-deoxyadenosin-5'-yl, which attacks the sugar substrate. Group: Enzymes. Synonyms: desII (gene name); eryCV (gene name); MegCV. Enzyme Commission Number: EC 4.3.1.30. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5290; dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase; EC 4.3.1.30; desII (gene name); eryCV (gene name); MegCV. Cat No: EXWM-5290. | |
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