A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
DTS(PTTh2)2 is a conjugating polymer with an absorption onset of 815 nm and a field effect hole mobility of ~ 0.1 cm2 V-1s-1. It acts as a small donor molecule that can be used as an active layer in optoelectronic applications. Uses: Narrow band gap material for high-efficiency organic solar cells (opvs) applicationopv device structure: ito/moox/dts(ptth2)2: pc70bm/al jsc = 14.4 ma/cm2 voc = 0.78 v ff = 0.59 pce = 6.7%. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 4, 4'-[4, 4-Bis(2-ethylhexyl)-4H-silolo[3, 2-b:4, 5-b']dithiophene-2, 6-diyl]bis[7-(5'-hexyl-[2, 2'-bithiophen]-5-yl)-[1, 2, 5]thiadiazolo[3, 4-c]pyridine]. Pack Sizes: 100 mg in glass insert. Product ID: 4-[7,7-bis(2-ethylhexyl)-10-[7-[5-(5-hexylthiophen-2-yl)thiophen-2-yl]-[1,2,5]thiadiazolo[3,4-c]pyridin-4-yl]-3,11-dithia-7-silatricyclo[6.3.0.02,6]undeca-1(8),2(6),4,9-tetraen-4-yl]-7-[5-(5-hexylthiophen-2-yl)thiophen-2-yl]-[1,2,5]thiadiazolo[3,4-c]pyridine. Molecular formula: 1185.9g/mol. Mole weight: C62H72N6S8Si. CCC (CCCC) C[Si]1 (CC (CCCC) CC) C2=C (SC (C3=NC=C (C4=CC=C (C5=CC=C (CCCCCC) S5) S4) C6=NSN=C63) =C2) C7=C1C=C (C8=NC=C (C9=CC=C (C%10=CC=C (CCCCCC) S%10) S9) C%11=NSN=C%118) S7. 1S / C62H72N6S8Si / c1-7-13-17-19-23-41-25-27-47 (69-41) 49-31-29-45 (71-49) 43-35-63-57 (59-55 (43) 65-75-67-59) 51-33-53-61 (73-51) 62-54 (77 (53, 37-39 (11-5) 21-15-9-3) 38-40 (12-6) 22
DTSSP
DTSSP. Pack Sizes: Milligram Quantities: 100 mg. Order Number: CL103.
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DTSSP Crosslinker
DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81069-02-5. Pack Sizes: 5 mg. Product ID: HY-126349.
DTSSP Crosslinker
DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins. Group: Biochemicals. Alternative Names: 1-3- [3- (2, 5-dioxo-3-sulfopyrrolidin-1-yl ) oxy-3-oxopropyl ] disulfanyl propanoyl oxy] -2, 5-dioxopyrrolidine-3-sulfonic acid; Sulfo-DSP; DTBSSP. Grades: Purified. CAS No. 81069-02-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
Worldwide
DTSSP Crosslinker
DTSSP Crosslinker. Uses: It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent. Synonyms: 3,3'-Dithiobis(sulphosuccinimidyl propionate); 3-pyrrolidinesulfonic acid, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis[2,5-dioxo-. Grade: ≥97.0%. CAS No. 81069-02-5. Molecular formula: C14H16N2O14S4. Mole weight: 564.54.
DTSSP Crosslinker (Sulfo-DSP; DTBSSP)
DTSSP is a water-soluble crosslinking agent with primary amine-reactivity, N-hydroxysulfosuccinimi de (Sulfo-NHS) esters at both ends and contains a cleavable, 8-atom (12A?) spacer arm. The disulfide bond in the spacer arm is cleavable with reducing agents such as DTT, TCEP, etc. DTSSP crosslinker is membrane-impermeable, thus enabling cell-surface crosslinking without interfering with intercellular proteins. Group: Biochemicals. Alternative Names: 1-? [3-? [3-? (2, 5-dioxo-?3-sulfopyrrolidin-1-yl ) oxy-3-oxopropyl ] disulfanyl propanoyl oxy] -2, 5-dioxopyrrolidine-3-sulfonic acid; Sulfo-DSP; DTBSSP. Grades: Highly Purified. CAS No. 81069-02-5. Pack Sizes: 250mg. US Biological Life Sciences.
DTT-8. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Terrylene. Product Category: Organic Photovoltaic (OPV). Appearance: solid. CAS No. 188-72-7. Molecular formula: C30H16. Mole weight: 376.45. Purity: 0.9. Product ID: ACM188727. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tribenzo[de,kl,rst]pentaphene, DTT in Ireland.
DTTCI
DTTCI (3,3-Diethylthiatricarbocyanine iodide) is an infrared photographic sensitizing dye. DTTCI is a highly sensitive chiroptical reporter of DNA helicity and sequence [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 3,3-Diethylthiatricarbocyanine iodide. CAS No. 3071-70-3. Pack Sizes: 250 mg; 500 mg. Product ID: HY-D1180.
DTTCI
DTTCI. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3,3'-Diethylthiatricarbocyanineiodide. Product Category: Other Fluorophores. Appearance: Green powder. CAS No. 3071-70-3. Molecular formula: C25H25N2S2I. Mole weight: 544.52. Purity: 98%+. IUPACName: (2Z)-3-ethyl-2-[(2E,4E,6E)-7-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)hepta-2,4,6-trienylidene]-1,3-benzothiazole;iodide. Canonical SMILES: CCN\1C2=CC=CC=C2S/C1=C\C=C\C=C\C=C\C3=[N+](C4=CC=CC=C4S3)CC.[I-]. Product ID: ACM3071703-3. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3,3'-Diethylthiatricarbocyanine iodide, DTT in Ireland.
DTT (Dithiothreitol)
100g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates. Formula: C4H10O2S2. CAS No. 3483-12-3. Prepack ID 19733320-100g. Molecular Weight 154.25. See USA prepack pricing.
DTT (Dithiothreitol)
25g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates. Formula: C4H10O2S2. CAS No. 3483-12-3. Prepack ID 19733320-25g. Molecular Weight 154.25. See USA prepack pricing.
DTT (Dithiothreitol)
5g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates. Formula: C4H10O2S2. CAS No. 3483-12-3. Prepack ID 19733320-5g. Molecular Weight 154.25. See USA prepack pricing.
dT-Thiophosphoramidite
dT-Thiophosphoramidite, a chemical compound utilized in the synthetic process of oligonucleotides, characterized as a class of biomolecules with vast implications in the biomedical arena, specifically for diagnostics, gene therapy, and drug development, adds to the the structural and functional modification of oligonucleotides as an indispensable building block. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-[pyrrolizino[[2-(benzoylthio)ethyl]thio]phosphino]thymidine. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97.
dTTPαS
dTTPαS is a modified nucleotide analogue used in enzymology and molecular biology research. It can be incorporated into DNA sequences during polymerase chain reaction (PCR) and is commonly used in site-directed mutagenesis studies. It has also been used in the study of DNA replication and repair mechanisms. Synonyms: 2'-Deoxythymidine-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95 % by HPLC. CAS No. 99749-43-6. Molecular formula: C10H17N2O13P3S.4Na. Mole weight: 586.19.
dTTP solution - Lithium Salt
dTTP could be used in the studies of DNA labeling reactions, polymerase chain reaction and sequencing/cycle sequencing analysis. Grade: ≥ 99 % by HPLC. Molecular formula: C10H17N2O14P3·xLi. Mole weight: 482.17 (free acid).
D-Turanose
D-Turanose, an exceptional carbohydrate embraced in the realm of biomedical industry, entices scientific intrigue. Esteemed for its pharmacological possibilities, this marvel has garnered profound attention for drug delivery systems and the amelioration of ailments such as diabetes and obesity. Its distinctive architecture empowers potent drug stability as well as meticulous release, thus rendering it an invaluable constituent within pharmaceutical formulations. Moreover, D-Turanose exhibits propitious prospects in tempering glycemic indices and orchestrating weight management, constituting a propelling contender for therapeutic interventions. Synonyms: Turanose; 3-O-(a-D-Glucopyranosyl)-D-fructose; 3-(α-D-Glucosido)-D-fructose; 3-O-α-D-Glucopyranosyl-D-fructose; D-(+)-Turanose; NSC 1222; (3S,4R,5R)-1,4,5,6-Tetrahydroxy-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-one. CAS No. 547-25-1. Molecular formula: C12H22O11. Mole weight: 342.30.
D-(+)-Turanose
1g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C12H22O11. CAS No. 547-25-1. Prepack ID 17058767-1g. Molecular Weight 342.3. See USA prepack pricing.
D-Tyr(13)-Semaglutide
D-Tyr(13)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: D-[Tyr]-13-Semaglutide. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64.
D-Tyr(2)-AVP
D-Tyr(2)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Tyr-Vasopressin; D-Tyr-AVP; Vasopressin, 2-D-tyrosine-8-L-arginine-; H-Cys-D-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-D-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-06-2. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Tyr5-Cetrorelix
An impurity of Cetrorelix. Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist used primarily in reproductive medicine and oncology. It works by competitively binding to GnRH receptors, thereby inhibiting the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn prevents ovulation and reduces the production of sex steroids. Synonyms: Ac-D2Nal-D4Cpa-D3Pal-Ser-DTyr-DCit-Leu-Arg-Pro-DAla-NH2; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-D-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2; N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-D-tyrosyl-D-citrullyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide; [D-Tyr]5-Cetrorelix; [D-Tyr5]-Cetrorelix; D-Tyr(5)-Cetrorelix. Grade: ≥95%. CAS No. 3031679-86-1. Molecular formula: C70H92ClN17O14. Mole weight: 1431.06.
D-Tyrosine benzyl ester 4-toluenesulfonate salt 98+% (HPLC)
D-Tyrosine benzyl ester 4-toluenesulfonate salt 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
D-Tyrosine-d4
D-Tyrosine-d4. Group: Biochemicals. Alternative Names: (2R) -2-Amino-3- (4-hydroxyphenyl) propanoic Acid-d4; (R)-Tyrosine-d4; D-p-Tyrosine-d4; H-D-Tyr-OH-d4. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C9H7D4NO3, Molecular Weight: 185.21. US Biological Life Sciences.
Worldwide
D-Tyrosine-[d4]
D-Tyrosine-[d4] is the labelled analogue of D-tyrosine. Tyrosine is a non-essential amino acid synthesized from phenylalanine. It is the precursor of some neurotransmitters. Synonyms: D-4-Hydroxyphenyl-2,3,5,6-d4-alanine; D-Tyrosine-(phenyl-d4); (2R)-2-Amino-3-(4-hydroxyphenyl)propanoic Acid-d4; (R)-Tyrosine-d4; D-p-Tyrosine-d4; H-D-Tyr-OH-d4; D-Tyrosine-d4; p-Hydroxyphenyl-D-alanine-d4; H-D-Tyr-OH-d4. Grade: ≥ 99% (CP); ≥ 98% atom D. CAS No. 944386-47-4. Molecular formula: C9H7D4NO3. Mole weight: 185.21.
D-Tyrosine,o-(1,1-dimethylethyl)-,2-propenyl ester,hydrochloride(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-D-TYR -ALLYLESTERHCL, 218962-74-4. Product Category: Heterocyclic Organic Compound. CAS No. 218962-74-4. Molecular formula: C16H23NO3·HCl. Mole weight: 313.82. Purity: 0.96. IUPACName: prop-2-enyl (2R)-2-amino-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoate;hydrochloride. Canonical SMILES: CC(C)(C)OC1=CC=C(C=C1)CC(C(=O)OCC=C)N.Cl. Product ID: ACM218962744. Alfa Chemistry ISO 9001:2015 Certified.
D-Tyrosine tert-butyl ester
D-Tyrosine tert-butyl ester. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
D-Tyrosinol hydrochloride. Group: Biochemicals. Alternative Names: D-Tyr-ol·HCl. Grades: Highly Purified. CAS No. 40829-04-7. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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D-Tyrosinol hydrochloride 99+% (HPLC)
D-Tyrosinol hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
D-Tyr-val
D-Tyr-val. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-TYR-VAL;D-TYR-VAL NH2;H-D-TYR-VAL-NH2;tyrosylvalinamide. Product Category: Heterocyclic Organic Compound. CAS No. 87237-39-6. Molecular formula: C14H20N2O4. Mole weight: 280.32. Purity: 0.96. IUPACName: 2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanamide. Canonical SMILES: CC(C)C(C(=O)N)NC(=O)C(CC1=CC=C(C=C1)O)N. Density: 1.207 g/cm³. Product ID: ACM87237396. Alfa Chemistry ISO 9001:2015 Certified.
DU125530
DU125530 is a selective 5-HT1A receptor antagonist (Ki = 0.7 nM). DU125530 has the potential to be used in the treatment of anxiety, depression and psychiatric disorders. Synonyms: DU-125530; DU125530; DU 125530; 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]butyl]-1,1-dioxo-1,2-benzothiazol-3-one. Grade: 99%. CAS No. 161611-99-0. Molecular formula: C23H26ClN3O5S. Mole weight: 491.99.
DU-14
DU-14 is a potent steroid sulfatase inhibitor with an IC 50 of 55.8 nM. DU-14 inhibits the MCF-7 cell proliferation ( IC 50 = 38.7 nM). DU-14 has neuroprotective effects against neurotoxic Aβ, suggesting that up-regulation of endogenous DHEAS by DU-14 could be beneficial to the alleviation of Aβ-induced impairments in spatial memory and synaptic plasticity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186303-55-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116377.
dU-3'-PS Phosphoramidite
dU-3'-PS Phosphoramidite is a deoxyuridine-derived phosphoramidite designed for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, significantly enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The uracil base remains unmodified, maintaining standard base-pairing properties during hybridization. This phosphoramidite is particularly valuable in therapeutic oligonucleotide applications, such as antisense oligonucleotides and siRNA, where improved stability, resistance to enzymatic degradation, and extended biological activity are critical. Synonyms: S-(2-(((((2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate; dU ThioPhosphamidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-DMT-dU-3'-PS-Phosphoramidite. Grade: ≥90%. Molecular formula: C43H46N3O8PS2. Mole weight: 827.95.
Dual AChE-MAO B-IN-1
Dual AChE-MAO B-IN-1 is an orally bioavailable CNS-permeant potent inhibitor of both human AChE (IC50 = 550 nM) and MAO B (IC50 = 8.2 nM). Dual AChE-MAO B-IN-1 has been used as a safe and metabolically stable neuroprotective agent, devoid of cytochrome liability. Molecular formula: C23H25F2NO4. Mole weight: 417.45.
dual-specificity kinase
This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. Group: Enzymes. Synonyms: ADK1; Arabidopsis dual specificity kinase 1; CLK1; dDYRK2; Mps1p. Enzyme Commission Number: EC 2.7.12.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3161; dual-specificity kinase; EC 2.7.12.1; ADK1; Arabidopsis dual specificity kinase 1; CLK1; dDYRK2; Mps1p. Cat No: EXWM-3161.
Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI - CAS 15982-84-0
The Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI controls the biological activity of Dual Specificity Protein Phosphatase 1/6. Primarily used for Phosphorylation & Dephosphorylation apps. Group: Fluorescence/luminescence spectroscopy.
Duazomycin A
Duazomycin A is produced by the strain of Streptomyces ambofaciens. It has the activity of anti-gram-positive bacteria, yeast and yeast-like fungi, and has strong inhibitory effect on sarcoma 180 and adenocarcinoma 755. Synonyms: Duazomycine; Duazomycinum; N-Acetyl-6-diazo-5-oxo-L-norleucine. CAS No. 2508-89-6. Molecular formula: C8H11N3O4. Mole weight: 213.19.
Dubermatinib
Dubermatinib (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TP-0903. CAS No. 1341200-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12963.
DUB-IN-2
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 ?M for USP8[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 924296-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50737A.
DUB Inhibitor IV, b-AP15 - CAS 1009817-63-4
The DUB Inhibitor IV, b-AP15 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable bis-nitrobenzylidene-piperidinone compound that acts as a potent, reversible and selective inhibitor of 19S regulatory-particle-associated deubiquitylating enzymes (DUBs) UCH-L5 and USP-14 (IC50=2.1uM against Ub-AMC substrate), with no effect on UCH-L1, UCH-L3, USP2, USP7, USP8 and BAP1 and on the proteasomal proteolytic activities. Shown to prevent proteasomal degradation (IC50=0.8uM in MelJuSo-UbG76V-YFP cells), and cause accumulation of higher molecular weights polyubiquitinated proteins in HCT-116 cells. Preferentially induces cell-cycle arrest and apoptosis in several colon cancer and in CNS cells, and effectively suppresses tumor growth in various mouse model (5mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. CAS No. 1009817-63-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 419.4. US Biological Life Sciences.
Worldwide
DUB Inhibitor VI, P22077
The DUB Inhibitor VI, P22077 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable thiophenylethanone that is shown to inhibit USP7 and USP47 deubiquitinase activity (IC50=8.01 & 8.74uM, respectively), while exhibiting much reduced affinity toward ATXN3, BAP1, and USP1, and displaying no inhibitory activity toward other known PR-619 targets (IC50 >50uM). Both P22077 and PR-619 are shown to increase overall protein polyubiquitination in HEK293T cells in a dose- and time-dependent manner (20 to 150uM; 0.5 to 20h), however PR619 treatment results in upregulation of both K48- and K63-linked, while P22077 exposure results in mainly enrichment of K48-linked polyUb chains. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
DUB Inhibitor V, PR-619
The DUB Inhibitor V, PR-619 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy.
DUB Inhibitor V, PR-619
A cell-permeable pyridinamine class broad-spectrum DUB inhibitor whose known targets include ATXN3, BAP1, JOSD2, OTUD5, UCH-L1, UCH-L3, UCH-L5/UCH37, USP1, 2, 4, 5, 7, 8, 9X, 10, 14, 15, 16, 19, 20, 22, 24, 28, 47, 48, VCIP135, YOD1, as well as deISGylase PLpro, deNEDDylase DEN1, and deSUMOlyase SENP6. Both PR-619 and P22077 are shown to increase overall protein polyubiquitination in HEK293T cells in a dose- and time-dependent manner (20 to 150uM; 0.5 to 20h), however P22077 exposure results in mainly enrichment of K48-linked, while PR619 treatment results in upregulation of both K48- and K63-linked polyUb chains. Group: Biochemicals. Alternative Names: PR619; UCH-L1 Inhibitor IV; UCH-L3 Inhibitor II; UCH-L5/UCH37 Inhibitor III; USP5 Inhibitor II; USP7 Inhibitor I; USP9X Inhibitor II; USP14 Inhibitor IV; USP14 Inhibitor IV; USP47 Inhibitor I; 2,6-Diaminopyridine-3,5-bis(thiocyanate); 3,5-Dithiocyanatopyridine-2,6-diamine. Grades: Highly Purified. CAS No. 21645-32-1. Pack Sizes: 25mg. Molecular Formula: C?H?N?S?, Molecular Weight: 223.3. US Biological Life Sciences.
Worldwide
DUBs-IN-1
DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor for USP7/USP8. Synonyms: DUBs-IN-1; DUBs IN 1. Grade: >98%. CAS No. 924296-18-4. Molecular formula: C20H11N5O. Mole weight: 337.33.
DUBs-IN-2
DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor for USP7/USP8. Synonyms: DUBs IN 2. Grade: >98%. CAS No. 924296-19-5. Molecular formula: C15H9N5O. Mole weight: 275.26.
DUBs-IN-3
DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor for USP8. It is 30 fold selectivity over USP7. Synonyms: DUBs-IN-3; DUBs IN 3. Grade: >98%. CAS No. 924296-17-3. Molecular formula: C16H9N5O. Mole weight: 287.28.
Ducheside A pentaacetate
Ducheside A pentaacetate.
Duck AvBD9
AvBD9 was differentially expressed in the tissues, with especially high levels of expression in liver, kidney, crop, and trachea. Duck AvBD9 exhibited antimicrobial activity against several bacterial strains. Synonyms: avian beta-defensins 9.
It is produced by the strain of Penicillum stipitatum. It has inhibitory effect on Ehrlician ascites carcinoma, lymphoma L-5178 and sarcoma 37. Synonyms: 15H-8,15a-Methano-3H,13H-benzo[de]cycloocta[1,2-g_3,4,5-d'e']bis[2]benzopyran-3,9,13,16-tetrone,17-(acetyloxy)-6b,7,8,15b-tetrahydro-4,12-dihydroxy-6b-methoxy-6,10-dimethyl-. CAS No. 1732-37-2. Molecular formula: C29H22O11. Mole weight: 546.48.
dU-CPG 1000
dU-CPG 1000 is a remarkable synthetic modified nucleotide. With improved stability and effectiveness of nucleic acids, dU-CPG 1000 is more effective in fighting a range of diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-succinoyl-long chain alkylamino-CPG 1000.