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| Product | Description | |
|---|---|---|
| Drotaverine Impurity 30 | Drotaverine Impurity 30. Uses: For analytical and research use. CAS No. 56046-20-9. Molecular formula: C24H27NO5. Mole weight: 409.48. Catalog: APB56046209. |  |
| Drotaverine Impurity 31 | Drotaverine Impurity 31. Uses: For analytical and research use. CAS No. 75500-95-7. Molecular formula: C22H27NO4. Mole weight: 369.46. Catalog: APB75500957. | |
| Drotaverine Impurity 32 | Drotaverine Impurity 32. Uses: For analytical and research use. CAS No. 56190-53-5. Molecular formula: C22H27NO4. Mole weight: 369.46. Catalog: APB56190535. | |
| Drotaverine Impurity 33 | Drotaverine Impurity 33. Uses: For analytical and research use. Molecular formula: C13H21NO2. Mole weight: 223.32. Catalog: APB07667. | |
| Drotaverine Impurity 4 | Drotaverine Impurity 4. Uses: For analytical and research use. CAS No. 27472-21-5. Molecular formula: C12H15NO2. Mole weight: 205.26. Catalog: APB27472215. | |
| Drotaverine Impurity 4 (Hydrochloride) | Drotaverine Impurity 4 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 3'-Desethoxy Drotaverine; 5-((6,7-diethoxy-3,4-dihydroisoquinolin-1-yl)methyl)-2-ethoxyphenol hydrochloride. CAS No. 85475-87-2. Molecular formula: C22H27NO4·HCl. Mole weight: 405.92. Catalog: APB85475872. | |
| Drotaverine Impurity 5 (Hydrochloride) | Drotaverine Impurity 5 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 4-((6,7-diethoxy-3,4-dihydroisoquinolin-1-yl)methyl)-2-ethoxyphenol hydrochloride. Molecular formula: C22H27NO4·HCl. Mole weight: 405.91. Catalog: APB05128. | |
| Drotaverine Impurity 6 (Hydrochloride) | Drotaverine Impurity 6 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 1-(3,4-diethoxybenzyl)-6-ethoxy-3,4-dihydroisoquinolin-7-ol hydrochloride. Molecular formula: C22H27NO4·HCl. Mole weight: 405.91. Catalog: APB05127. | |
| Drotaverine Impurity 7 (Hydrochloride) | Drotaverine Impurity 7 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 1-(3,4-diethoxybenzyl)-7-ethoxy-3,4-dihydroisoquinolin-6-ol hydrochloride. Molecular formula: C22H27NO4·HCl. Mole weight: 405.91. Catalog: APB05126. | |
| Drotaverine Impurity 8 | Drotaverine Impurity 8. Uses: For analytical and research use. Alternative Names: 1-(2-(2-aminoethyl)-4,5-diethoxyphenyl)-2-(3,4-diethoxyphenyl)ethanone. Molecular formula: C24H33NO5. Mole weight: 415.52. Catalog: APB05125. | |
| Drotaverine Impurity 9 | Drotaverine Impurity 9. Uses: For analytical and research use. Alternative Names: 1-(3,4-diethoxybenzyl)-6,7-diethoxy-3,4-dihydroisoquinoline 2-oxide. Molecular formula: C24H31NO5. Mole weight: 413.51. Catalog: APB05124. | |
| Droxicainide hydrochloride | The hydrochloride salt form of Droxicainide, a piperidine derivative, has been found to be an potential antiarrhythmic agent. Synonyms: Droxicainide hydrochloride; AL-S 1249; Droxicainide HCl; S 1249; S-1249; UNII-91801A0812. (+-)-N-(2-Hydroxyethyl)pipecolinyl-2,6-dimethylanilide hydrochloride; S-1249; (+-)-N-(2,6-Dimethylphenyl)-1-(2-hydroxyethyl)-2-piperidinecarboxamide monohydrochloride; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)-, monohydrochloride. Grade: 98%. CAS No. 149572-05-4. Molecular formula: C16H25ClN2O2. Mole weight: 312.84. |  |
| Droxidopa | Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Synonyms: (βR)-β,3-Dihydroxy-L-tyrosine; threo-β,3-Dihydroxy-L-tyrosine; L-threo-3-(3,4-Dihydroxyphenyl)serine; (-)-threo-3,4-Dihydroxyphenylserine; (2S,3R)-3-(3,4-Dihydroxyphenyl)-2-amino-3-hydroxypropanoic Acid; DOPS; L-DOPS; L-Threodops; L-threo-3,4-Dihydroxyphenylserine; L-threo-DOPS; L-threo-β-(3,4-Dihydroxyphenyl)serine; SM 5688; threo-Dopaserine. Grade: >98%. CAS No. 23651-95-8. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| Droxidopa | Droxidopa (L-DOPS; SM5688) is a potent, orally active norepinephrine precursor. Droxidopa increases standing blood pressure, ameliorates symptoms of orthostatic hypotension and improves standing ability. Droxidopa has the potential for the research of neurogenic orthostatic hypotension (nOH) and alternative ADHD (attention deficit hyperactivity disorder)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-DOPS; DOPS; SM5688. CAS No. 23651-95-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 1 g. Product ID: HY-13458. |  |
| Droxidopa impurity 1 | Droxidopa impurity 1. Uses: For analytical and research use. CAS No. 16322-99-9. Molecular formula: C9H11NO5. Mole weight: 213.19. Catalog: APB16322999. | |
| Droxidopa Impurity 1 | Droxidopa Impurity 1. Uses: For analytical and research use. Alternative Names: 2-(3,4-dihydroxyphenyl)-2-hydroxyacetaldehyde. CAS No. 13023-73-9. Molecular formula: C8H8O4. Mole weight: 168.15. Catalog: APB13023739. | |
| Droxidopa Impurity 10 | Droxidopa Impurity 10. Uses: For analytical and research use. Alternative Names: (2S,3R)-2-amino-3-(benzo[d][1,3]dioxol-5-yl)-3-hydroxypropanoic acid. CAS No. 88375-62-6. Molecular formula: C10H11NO5. Mole weight: 225.20. Catalog: APB88375626. | |
| Droxidopa Impurity 11 | Droxidopa Impurity 11. Uses: For analytical and research use. Alternative Names: 2-hydroxyisoindoline-1,3-dione. CAS No. 524-38-9. Molecular formula: C8H5NO3. Mole weight: 163.13. Catalog: APB524389. | |
| Droxidopa Impurity 12 | Droxidopa Impurity 12. Uses: For analytical and research use. Alternative Names: 2,3,8,9-tetrahydroxy-5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-5-carboxylic acid. Molecular formula: C17H15NO6. Mole weight: 329.30. Catalog: APB05134. | |
| Droxidopa Impurity 14 | Droxidopa Impurity 14. Uses: For analytical and research use. Alternative Names: 2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid. CAS No. 3916-18-5. Molecular formula: C9H11NO5. Mole weight: 213.19. Catalog: APB3916185. | |
| Droxidopa impurity 2 | Droxidopa impurity 2. Uses: For analytical and research use. Molecular formula: C17H15ClN2O7. Mole weight: 394.76. Catalog: APB11654. | |
| Droxidopa Impurity 2 | Droxidopa Impurity 2. Uses: For analytical and research use. Alternative Names: 2-(3,4-dihydroxyphenyl)acetaldehyde. CAS No. 5707-55-1. Molecular formula: C8H8O3. Mole weight: 152.15. Catalog: APB5707551. | |
| Droxidopa impurity 3 | Droxidopa impurity 3. Uses: For analytical and research use. Molecular formula: C16H14N2O5. Mole weight: 314.3. Catalog: APB11655. | |
| Droxidopa Impurity 3 | Droxidopa Impurity 3. Uses: For analytical and research use. Alternative Names: (2R,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid. CAS No. 51829-98-2. Molecular formula: C9H11NO5. Mole weight: 213.19. Catalog: APB51829982. | |
| Droxidopa Impurity 4 | Droxidopa Impurity 4. Uses: For analytical and research use. Alternative Names: (2S,3R)-2-(((benzyloxy)carbonyl)amino)-3-(3,4-bis(benzyloxy)phenyl)-3-hydroxypropanoic acid. CAS No. 55382-14-4. Molecular formula: C31H29NO7. Mole weight: 527.56. Catalog: APB55382144. | |
| Droxidopa Impurity 5 | Droxidopa Impurity 5. Uses: For analytical and research use. Alternative Names: 51829-99-3 (free base); (2R,3S)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid hydrochloride. Molecular formula: C9H11NO5·HCl. Mole weight: 249.65. Catalog: APB05136. | |
| Droxidopa Impurity 6 | Droxidopa Impurity 6. Uses: For analytical and research use. Alternative Names: 5,6,11,12-tetrahydro-5,11-epiminodibenzo[a,e][8]annulene-2,3,8,9-tetraol. CAS No. 90044-46-5. Molecular formula: C16H15NO4. Mole weight: 285.29. Catalog: APB90044465. | |
| Droxidopa Impurity 7 | Droxidopa Impurity 7. Uses: For analytical and research use. Alternative Names: (2S,3R)-2-amino-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoic acid. CAS No. 28865-97-6. Molecular formula: C10H13NO5. Mole weight: 227.21. Catalog: APB28865976. | |
| Droxidopa Impurity 8 | Droxidopa Impurity 8. Uses: For analytical and research use. Alternative Names: (2S,3S)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid. CAS No. 34047-62-6. Molecular formula: C9H11NO5. Mole weight: 213.19. Catalog: APB34047626. | |
| Droxidopa Impurity 9 | Droxidopa Impurity 9. Uses: For analytical and research use. Alternative Names: (2S,3R)-2-amino-3-(3-(benzoyloxy)-4-hydroxyphenyl)-3-hydroxypropanoic acid. Molecular formula: C16H15NO6. Mole weight: 317.29. Catalog: APB05135. | |
| Droxinostat | Droxinostat (NS 41080) is a histone deacetylase (HDAC) inhibitor. Droxinostat selectively inhibits HDAC3, HDAC6, and HDAC8 with IC50 values of 16.9 μM, 2.47 μM, and 1.46 μM, respectively. Droxinostat can be used for the research of hepatocellular carcinoma (HCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NS 41080. CAS No. 99873-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13267. | |
| Droxinostat | Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8. Droxinostat shows comparable inhibition of HDAC6 and HDAC8 (IC50 = 2.47 and 1.46 μmol/L, respectively). Synonyms: NS 41080; NS-41080; NS41080; 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide. CAS No. 99873-43-5. Molecular formula: C11H14ClNO3. Mole weight: 243.687. | |
| Droxinostat | Droxinostat. Group: Biochemicals. Alternative Names: 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide; NS 41080. Grades: Highly Purified. CAS No. 99873-43-5. Pack Sizes: 10mg. Molecular Formula: C11H14ClNO3, Molecular Weight: 243.69. US Biological Life Sciences. |  Worldwide |
| Drozitumab | Drozitumab (PRO 95780) is a human agonistic monoclonal antibody which binds the death receptor DR5. Drozitumab has potent antitumor activity against rhabdomyosarcoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody. CAS No. 912628-39-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99286. | |
| Drozitumab | Drozitumab is a human monoclonal antibody directed against DR5. DR5 is a ell surface receptor of the TNF-receptor superfamily that binds TRAIL and mediates apoptosis. Study showed that Drozitumab was effective against Rhabdomyosarcoma cell lines. Synonyms: PRO-95780; PRO 95780; PRO95780; rhuMAb-DR 5. Grade: 95%. CAS No. 912628-39-8. Molecular formula: C6334H9792N1700O2000S42. Mole weight: 143.1 kDa. | |
| DRP1 Antibody [H2B5] | DLP1,DNM1L,DRP1. Group: Antibodies. Alternative Names: DLP1,DNM1L,DRP1. Pack Sizes: 20ul. Product ID: F0328. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| DRP1i27 | DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1453028-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-152086. | |
| Drp1-IN-1 | Drp1-IN-1 is a dynamin-1-like protein (Drp1) inhibitor with an IC50 of 0.91 μM. Drp1 mediates the fission of the outer mitochondrial membrane. Drp1-IN-1 can be used to study diseases associated with mitochondrial dysfunction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2247733-08-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125222. | |
| Drp1 peptide inhibitor P110 | Drp1 peptide inhibitor P110 (Compound P110) is a selective Drp1 peptide inhibitor with neuroprotective properties. Drp1 peptide inhibitor P110 can inhibit the activation of Drp1, prevent MPTP-induced Drp1 mitochondrial translocation, and alleviate MPTP-induced dopaminergic neuron loss, dopaminergic nerve terminal damage, and behavioral deficits, and can be used in the study of Alzheimer's disease. Additionally, Drp1 peptide inhibitor P110 can reduce mitochondrial damage and organ injury in animal models of Huntington's disease, cerebral ischemic injury, and myocardial infarction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2770267-63-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P6437. | |
| DRP-PBN1 | PBN1 is an antimicrobial peptide found in Phyllomedusa bicolor (South American two-colored leaf frog), and has antibacterial activity. Synonyms: PBN1; H-Phe-Leu-Ser-Leu-Ile-Pro-His-Ile-Val-Ser-Gly-Val-Ala-Ala-Leu-Ala-Lys-His-Leu-Gly-OH; Antimicrobial peptide, Dermaseptin-like peptide PBN1. Grade: ≥96%. Molecular formula: C97H159N25O23. Mole weight: 2043.48. | |
| Drug-Fragment Library | Quantity: 1159 drug fragments?a must-have tool for FBDD; - Physiochemical properties: 53% of fragments are Ro3 compliant?and all fragments matching with approved drugs or clinical compounds will have the best drug potential; - Quality guaranteed: NMR and HPLC/LCMS validated to ensure high purity and quality; - Applicable to various detection methods: suitable for SPR, NMR, and X-ray crystallization screening. Uses: Scientific use. Product Category: L8800. Categories: Drug-Fragment Libraries. |  |
| Drug-induced Liver Injury (DILI) Compound Library | A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening?- Include anti-cancer drugs, antibiotics, antituberculotic agents, antiretrovirals, antiepileptic agents, and cardiac medications, etc. ?- Diversified in toxicities: Steatosis, Mitochondrial toxicity, cholestasis, drug allergy (hypersensitivity), etc. ; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5510. Categories: Drug-induced Liver Injury (DILI) Compounds Libraries. | |
| Drug Metabolite/Impurity Library | A unique collection of 200 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS); - Structurally diverse, medicinally active, and cell permeable; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5800. Categories: Drug Metabolite/Impurity Libraries. | |
| Drug Repurposing Compound Library | A unique collection of 4240 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS); - An effective tool for discovering new with old drugs, cell induction, and new drug target screening; - All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary; - Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc. - Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc. - Detailed compound information with structure, target, activity, and brief introduction; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L9200. Categories: Drug Repurposing Compounds Libraries. | |
| Drum Dried Purple Sweet Potato Powder | Drum Dried Purple Sweet Potato Powder. |  CA, FL & NJ |
| Drupanin | Drupanin is an orally active and selective AKR1C3 enzyme inhibitor and an RXRα agonist with an EC50 value of 4.8 μM, which is found in green propolis. Drupanin also activates PPARγ moderately. Drupanin induces adipogenesis and elevates aP2 mRNA levels in 3T3-L1 fibroblasts Drupanin has the potential for the research of breast and prostate cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 53755-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N10361. | |
| DRX-065 | DRX-065 is a deuterated R enantiomer of pioglitazone, an antidiabetic drug. DRX-065 exhibits anti-inflammatory property without weight-gain side effect of S enatiomer. Synonyms: deuterated R-enantiomer of pioglitazone; (R)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione-5-d. CAS No. 1259828-75-5. Molecular formula: C19H19DN2O3S. Mole weight: 357.126. | |
| Dryfast Foam-Type 1 | Dryfast foams are suited for outdoor use where moisture and precipitation like rain is prevalent, such as in patio furniture, including under Phifertex material, or in marine cushioning on personal watercraft. The large, open cells provide a degree of airflow not present in other foams, allowing it to dry quickly, even after complete saturation. |  |
| Dryfast Foam-Type 2 | Dryfast foams are suited for outdoor use where moisture and precipitation are prevalent, such as in patio furniture, including under Phifertex material, or in marine cushioning on personal watercraft. The large, open cells provide a degree of airflow not present in other foams, allowing it to dry quickly, even after complete saturation. | |
| DRY VITAMIN A PALMITATE ,TYPE250CWS | DRY VITAMIN A PALMITATE ,TYPE250CWS. Product ID: ACMA00005829. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| DS02312223 | DS02312223 (D223) is a molecular glue that promotes the binding of RAS to PI3Kα, with a Kd of 0.76 μM for p110α. DS02312223 increases the binding affinity between GTP-bound KRAS (KRAS-GMPPNP) and p110α by nearly three orders of magnitude (KD = 0.017 μM). DS02312223 stimulates the translocation of GLUT4 to the plasma membrane. DS02312223 promotes glucose uptake in the absence of insulin. DS02312223 can be used in diabetes research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D223. CAS No. 2253733-45-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W1126235. | |
| DS08210767 | DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2376334-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125879. | |
| DS-1001b | DS-1001b is an oral selective inhibitor of mutant IDH1 R132X. DS-1001b impaired the proliferation of chondrosarcoma cells with IDH1 mutations in vitro and in vivo, and decreased 2-HG levels. Synonyms: DS-1001; DS 1001; DS1001. CAS No. 1898207-64-1. Molecular formula: C29H29Cl3FN3O4. Mole weight: 608.92. | |
| DS-1040 Tosylate | DS-1040 inhibits the activated form of thrombin-activatable fibrinolysis inhibitor (TAFIa), used for the treatment of acute ischemic stroke (AIS). DS-1040 substantially decreased TAFIa activity but had no impact on bleeding time. DS-1040 may provide an option of safer thrombolytic therapy. Synonyms: DS-1040 Tosylate; DS 1040 Tosylate; DS1040 Tosylate; (2S)-5-amino-2-[[1-(4-methylcyclohexyl)imidazol-4-yl]methyl]pentanoic acid; 4-methylbenzenesulfonic acid; DS-1040 (Tosylate). CAS No. 1335138-89-0. Molecular formula: C23H35N3O5S. Mole weight: 465.61. | |
| DS-1205b free base | DS-1205b free base, a potent and selective AXL kinase inhibitor with an IC50 of 1.3 nM, inhibits cell migration in vitro and tumor growth in vivo. It also inhibits MER, MET and TRKA with IC50s of 63, 104 and 407 nM, respectively. Synonyms: (R)-N-(4-(5-(4-((1,4-Dioxan-2-yl)methoxy)-3-methoxyphenyl)-2-aminopyridin-3-yl)-3-fluorophenyl)-5-methyl-4'-oxo-1'-((tetrahydro-2H-pyran-4-yl)methyl)-1',4'-dihydro-[2,3'-bipyridine]-5'-carboxamide; N-[4-(2-Amino-5-{4-[(2R)-1,4-dioxan-2-ylmethoxy]-3-methoxyphenyl}-3-pyridinyl)-3-fluorophenyl]-5-methyl-4'-oxo-1'-(tetrahydro-2H-pyran-4-ylmethyl)-1',4'-dihydro-2,3'-bipyridine-5'-carboxamide; DS-1205b; DS-1205. Grade: ≥95%. CAS No. 1855860-24-0. Molecular formula: C41H42FN5O7. Mole weight: 735.80. | |
| DS-1558 | This active molecular is a potent GPR40 agonist and it was found to have potent glucose lowering effects during an oral glucose tolerance test in animal models. DS-1558 improved hyperglycemia and increased insulin secretion dose-dependently during the oral glucose tolerance test in Zucker fatty rats. Uses: Improve hyperglycemia and increase insulin secretion. Synonyms: DS-1558; DS 1558; DS1558; (S)-3-ethoxy-3-(4-(((R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)oxy)phenyl)propanoic acid. Grade: 98%. CAS No. 1202575-67-4. Molecular formula: C21H21F3O4. Mole weight: 394.39. | |
| DS16570511 | DS16570511 is an inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca2+ influx. It inhibits calcium uptake by mitochondria isolated from HEK293A cells, rat heart, and pig heart (IC50s = 0.86, 25, and 15 μM, respectively). Synonyms: 4-(3-(3-(((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methyl)amino)benzoyl)-1H-indol-1-yl)butanoic acid. Grade: ≥95%. Molecular formula: C30H25Cl2N3O4. Mole weight: 562.44. | |
| DS18561882 | DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 (IC50=0.57 μM). DS18561882 exhibits a good oral pharmacokinetic profile[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2227149-22-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130251. | |
| DS-1971a | DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1450595-86-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131182. | |
| DS-1971a | DS-1971a is a potent and selective NaV1.7 inhibitor. DS-1971a is expected to exert potent efficacy in patients with peripheral neuropathic pain, with a favorable safety profile. Synonyms: DS-1971. Grade: 98% by HPLC. CAS No. 1450595-86-4. Molecular formula: C20H21ClFN5O3S. Mole weight: 465.9. | |
| DS2 | DS2 has been found to be a positive allosteric modulator of δ-GABAA receptors and could probably be useful against analgesics as well as sleep disorders. Synonyms: DS2; DS-2; DS 2; 4-Chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridin-3-yl]benzamide. Grade: ≥97% by HPLC. CAS No. 374084-31-8. Molecular formula: C18H12ClN3OS. Mole weight: 353.83. | |
| DS2 | DS2. Group: Biochemicals. Grades: Purified. CAS No. 374084-31-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| DS20362725 | DS20362725, an agonist of estrogen-related receptor α (ERRα), inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide and GST-ERRα ligand-binding domain (LBD) with an IC50 of 0.6 μM. It can be used to study metabolic disorders, including type 2 diabetes mellitus (T2DM). Synonyms: Phenol, 4-[(1,2-dimethyl-1H-benzimidazol-6-yl)oxy]-2-(1,1-dimethylethyl)-; 2-(tert-butyl)-4-((1,2-dimethyl-1H-benzo[d]imidazol-6-yl)oxy)phenol. CAS No. 2735803-20-8. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| DS21150768 | DS21150768 is a potent, orally active HPK1 inhibitor. DS21150768 shows potent activity to enhance T-cell function. DS21150768 has anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3074816-62-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157149. | |
| DS21360717 | DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304654-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128576. | |
| DS-2248 | DS-2248 is an orally active and small molecule inhibitor of Hsp90, with potential antineoplastic activity. Upon oral administration, Hsp90 inhibitor DS-2248 specifically blocks Hsp90, which inhibits its chaperone function and promotes the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may result in an inhibition of tumor cell proliferation. Synonyms: DS2248; DS-2248; DS 2248. Grade: >98%. CAS No. 1696408-04-4. | |
| DS-3801b | DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1369412-66-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144401. | |
| DS-437 | DS-437 is a dual PRMT5/7 inhibitor (IC50s of PRMT5/7=6 μM). DS-437 is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. DS-437 is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5. DS-437 also inhibits DNMT3A and DNMT3B, with IC50s of 52 and 62 μM, respectively. DS-437 inhibits the methylation of FOXP3[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1674364-87-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124131. | |
| DS-437 | DS-437 is a dual inhibitor of protein arginine methyltransferase 5/7 (PRMT5/7) with IC50s of 5.9 and 6 μM, respectively. It is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. It is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5, and inhibits the methylation of FOXP3, and inhibits DNMT3A and DNMT3B with IC50s of 52 and 62 μM, respectively. Synonyms: 5'-S-[2-[[(ethylamino)carbonyl]amino]ethyl]-5'-thio-adenosine; 5'-S-{2-[(Ethylcarbamoyl)amino]ethyl}-5'-thioadenosine. Grade: ≥95%. CAS No. 1674364-87-4. Molecular formula: C15H23N7O4S. Mole weight: 397.45. | |
| DS44960156 | DS44960156 is a selective MTHFD2 inhibitor with moderate to low blood-brain barrier penetration (IC50=1.6 μM, Ki=1.23 μM). DS44960156 specifically binds to the active site of MTHFD2, disrupts redox homeostasis and blocks serine-mediated one-carbon metabolism, thereby increasing the NAD+/NADH ratio and ROS levels. DS44960156 not only effectively inhibits the proliferation of glioma cells, but also enhances the sensitivity of cells to glutamine starvation-induced death. DS44960156 binds to plasma proteins, shows no mutagenicity, carcinogenicity or acute oral toxicity, and serves as a research agent for glioblastoma multiforme and other cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361327-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131943. | |
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