A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
ddATP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyadenosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154902-26-8. Molecular formula: C10H16N5O10P3S (free acid). Mole weight: 491.3 (free acid).
ddATP trisodium solution (100 mM)
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2',3'-Dideoxyadenosine 5'-triphosphate trisodium. CAS No. 72029-21-1. Pack Sizes: 100 μL; 200 μL; 500 μL; 1 mL. Product ID: HY-128036B.
ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dCTP in cells. Uses: Ddctp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxycytidine-5'-Triphosphate; Zalcitabine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-. Grade: ≥95% by AX-HPLC. CAS No. 66004-77-1. Molecular formula: C9H16N3O12P3 (free acid). Mole weight: 451.16 (free acid).
ddCTP-α-S
ddCTP-α-S is used in mass spectrometry genotyping. Synonyms: 2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-49-0. Molecular formula: C9H16N3O11P3S (free acid). Mole weight: 467.2 (free acid).
DDD107498
DDD107498 is a novel multiple-stage antimalarial agent that inhibits P. falciparum translation elongation factor 2. Synonyms: M-5717; DDD-498; DDD498; DDD-107498. CAS No. 1469439-69-7. Molecular formula: C27H31FN4O2. Mole weight: 462.56.
DDD107498 succinate
DDD107498 succinate is a potent and orally active antimalarial inhibitor. It inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Synonyms: DDD-498 succinate. Grade: 99%. CAS No. 2444781-71-7. Molecular formula: C31H37FN4O6. Mole weight: 580.65.
DDD-85365
DDD-85365 is an oral drug developed promisingly for the treatment of visceral leishmaniasis. Uses: The potential treatment of visceral leishmaniasis. Synonyms: DDD 85365; DDD85365.
DDD85646
DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. Synonyms: IMP-366; 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide. Grade: ≥98%. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.4.
DDD85646
DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMP-366. CAS No. 1215010-55-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103056.
Dde Biotin-PEG4-alkyne is a polyethylene glycol (PEG)-based PROTAC linker. Dde Biotin-PEG4-alkyne can be used in the synthesis of a series of PROTACs. CAS No. 1802908-00-4. Molecular formula: C32H50N4O8S. Mole weight: 650.83.
Dde Biotin-PEG4-azide
Dde Biotin-PEG4-azide is useful for introducing a biotin moiety to alkyne-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine. Please contact us for GMP-grade inquiries. Synonyms: Dde Biotin-PEG4-Azide; 1802907-93-2; Dde Biotin Azide; AKOS040741615; BP-22678. Grade: 0.95. CAS No. 1802907-93-2. Molecular formula: C32H53N7O8S. Mole weight: 695.9.
Dde Biotin-PEG4-azide
Dde Biotin-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802907-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140916.
Dde Biotin-PEG4-DBCO
Dde Biotin-PEG4-DBCO is a polyethylene glycol (PEG)-based PROTAC linker. Dde Biotin-PEG4-DBCO can be used in the synthesis of a series of PROTACs. CAS No. 1807512-43-1. Molecular formula: C47H61N5O9S. Mole weight: 872.08.
Dde Biotin-PEG4-Picolyl azide
Dde Biotin-PEG4-Picolyl azide is a polyethylene glycol (PEG)-based PROTAC linker. Dde Biotin-PEG4-Picolyl azide can be used in the synthesis of a series of PROTACs. CAS No. 2055048-42-3. Molecular formula: C38H57N9O9S. Mole weight: 815.98.
D-Decamannuronic acid decasodium salt
D-decamannuronic acid decasodium salt is an invaluable biomedical breakthrough facilitating targeted researchs for diverse diseases, encompassing inflammatory conditions, bacterial infections and immune disorders. Grade: ≥93% by GPC. Molecular formula: C60H72O61Na10. Mole weight: 1999.07.
D-Desosamine is a sugar of innate origins bravely hindering bacterial proliferation, particularly augmenting erythromycin's power. Synonyms: D-xylo-Hexose, 3,4,6-trideoxy-3-(dimethylamino)-; 3,4,6-trideoxy-3-dimethylamino-D-xylo-hexose; 3-Dimethylamino-3,4,6-trideoxy-D-xylo-hexose. Grade: ≥95%. CAS No. 5779-39-5. Molecular formula: C8H17NO3. Mole weight: 175.23.
D-Desthiobiotin
D-Desthiobiotin is an analogue of Biotin and a protein cross-linking agent. It is used in the preparation of agarose matrices for affinity-based isolation of streptavidin-fluorophore conjugates. Synonyms: Desthiobiotin; Dethiobiotin; d-Dethiobiotin; (+)-Dethiobiotin; ε-(4-Methyl-5-imidazolidone-2)caproic Acid; (4R,5S)-5-Methyl-2-oxo-4-imidazolidinehexanoic Acid; (4R-cis)-5-methyl-2-oxo-4-Imidazolidinehexanoic Acid; 4-Methyl-5-(ω-carboxyamyl)imidazolidone; 5-Methyl-2-oxo-4-imidazolidinecaproic Acid. Grade: ≥95% by HPLC. CAS No. 533-48-2. Molecular formula: C10H18N2O3. Mole weight: 214.26.
D-Desthiobiotin
D-Desthiobiotin is a biotin derivative. D-Desthiobiotin increases testosterone. D-Desthiobiotin is used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dethiobiotin. CAS No. 533-48-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-128699.
D-Desthiobiotin-7-dATP
D-Desthiobiotin-7-dATP is a vital component in biomedical research, widely used for DNA labeling and sequencing applications. It serves as a high-affinity substrate for certain DNA polymerases and DNA-modifying enzymes. This product aids in the study of DNA-protein interactions. Synonyms: N6-(6-Amino)hexyl-dATP - D-Desthiobiotin; N6-(6-Amino)hexyl-2'-deoxyadenosine-5'-triphosphate - D-Desthiobiotin, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C26H45N8O14P3. Mole weight: 786.6.
Dde TAMRA Biotin Alkyne
Dde TAMRA Biotin Alkyne is a trifunctional, cleavable probe that allows for efficient recovery of avidin-bound protein complexes in affinity-based assays. This reagent contains a fluorescent dye (TAMRA) and biotin moiety linked to azide group through a spacer arm containing a hydrazine-cleavable Dde moiety. Under mild conditions (2% aqueous hydrazine), the Dde liner is cleaved, releasing the biotin tag and any avidin conjugate bound to it. CAS No. 2353409-55-7. Molecular formula: C72H100N9O18S. Mole weight: 1411.7.
ddGTP
ddGTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddGTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dGTP in cells. Uses: Ddgtp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxyguanosine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 68726-28-3. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid).
ddGTP-α-S
ddGTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyguanosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-50-3. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.3 (free acid).
D-Dicentrine
Botanical Source: Group: Biochemicals. Alternative Names: (S)-form,(+)-Dicentrine. Grades: Plant Grade. CAS No. 517-66-8. Pack Sizes: 20mg. US Biological Life Sciences.
Worldwide
D-Digitalose
D-Digitalose is an advanced pharmacological compound, exhibiting utmost proficiency in studying the complexities of heart failure and irregular cardiac rhythms. This compound is classified under the realm of cardiac glycosides. Synonyms: 6-Deoxy-3-O-methyl-D-galactose. CAS No. 4481-8-7. Molecular formula: C7H14O5. Mole weight: 178.18.
D-Digitoxose Tribenzoate
D-Digitoxose derivative. A derivative of D-ribo-Hexonic acid that liver metabolized. It is a glucose-stimulated insulin release inhibitor. Synonyms: 2,6-Dideoxy-β-D-ribo-hexopyranose Tribenzoate. CAS No. 104652-04-2. Molecular formula: C27H24O7. Mole weight: 460.48.
D-Dimethylbenzoyl tartaric acid Impurity 1
D-Dimethylbenzoyl tartaric acid Impurity 1. Uses: For analytical and research use. Alternative Names: (3S,4S)-4-hydroxy-2,5-dioxotetrahydrofuran-3-yl 2-methylbenzoate. Molecular formula: C12H10O6. Mole weight: 250.05. Catalog: APB03720.
D-Dimethylbenzoyl tartaric acid Impurity 2
D-Dimethylbenzoyl tartaric acid Impurity 2. Uses: For analytical and research use. Alternative Names: (2R,3R)-2,3-bis((2-methylbenzoyl)oxy)succinic acid. Molecular formula: C20H18O8. Mole weight: 386.10. Catalog: APB03719.
D(-)-Dimethyl D-tartrate 99+%
D(-)-Dimethyl D-tartrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
DDL-357
DDL-357 is a potent secreted clusterin enhancer. DDL-357 reduces phospho-tau in brain and improves memory in the murine 3xTg-AD model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077900-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176438.
DDMS
DDMS (Dibromo-dodecenyl-methylsulfimide) is a selective 20-HETE production inhibitor. DDMS attenuates the vasodilatory response to sodium nitroprusside (SNP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dibromo-dodecenyl-methylsulfimide. CAS No. 206052-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121188.
DDMS
DDMS is a mechanism-based irreversible inhibitor with a 10-fold selectivity for CYP4A2 enzymes, which are mainly synthesized into 20-hete in mammalian kidneys. Synonyms: Dibromo-dodecenyl-methylsulfimide; 12,12-Dibromo-N-(methylsulfonyl)-11-dodecenamide. Grade: ≥98%. CAS No. 206052-03-1. Molecular formula: C13H23Br2NO3S. Mole weight: 433.2.
ddNTP bundle
ddNTP bundle is a mixture of ddATP, ddTTP, ddGTP and ddCTP. ddNTP is an inhibitor of DNA polymerase used to terminate chain extension. Uses: Ddntp is an inhibitor of dna polymerase. Synonyms: 2',3'-Dideoxyadenosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxycytidine-5'-triphosphate, Lithium salt; 2',3'-Dideoxyguanosine-5'-triphosphate, Lithium salt; 2',3'-Dideoxythymidine-5'-triphosphate, Lithium salt. Grade: ≥ 98% by HPLC, functionally tested by chain termination sequencing reactions. Molecular formula: ddATP: C10H16N5O11P3 (free acid); ddCTP: C9H16N3O12P3 (free acid); ddGTP: C10H16N5O12P3 (free acid); ddTTP: C10H17N2O13P3 (free acid). Mole weight: ddATP: 475.18 (free acid); ddCTP: 451.16 (free acid); ddGTP: 491.18 (free acid); ddTTP: 466.17 (free acid).
DDO-2093
DDO-2093 is a potent inhibitor of MLL1-WDR5 protein-protein interaction with an IC50 of 8.6 nM and a Kd of 11.6 nM. It shows antitumor activity and selectively inhibits the catalytic activity of MLL complex. Synonyms: 1H-1,2,3-Triazole-4-carboxamide, 1-[3-[(5-amino-2-chloro-4-fluoro-3-methylbenzoyl)amino]-4-(4-methyl-1-piperazinyl)phenyl]-N-[3-(4-morpholinyl)propyl]-. CAS No. 2250024-74-7. Molecular formula: C29H37ClFN9O3. Mole weight: 614.11.
DDO-2213
DDO-2213 is an orally active and potent WDR5-MLL1 inhibitor, with an IC50 of 29 nM and a Kd value of 72.9 nM for the WDR5 protein. DDO-2213 selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity and the proliferation of MLL translocation-harboring cells. DDO-2213 can be used for MLL fusion leukemia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378768-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153331.
DDO-2728
DDO-2728 (compound 19) is a selective AlkB homologue 5 (ALKBH5) inhibitor with an IC50 of 2.97 μM. DDO-2728 increases the abundance of N6 methyladenosine (m6A) modifications, inducing cell apoptosis and cycle arrest. DDO-2728 suppresses tumor growth in the MV4 11 xenograft model with favorable safety profile, shows the potential of targeting ALKBH5 in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3029515-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155489.
DDO-5936
DDO-5936 is a potent Hsp90-Cdc37 PPI inhibitor. DDO-5936 disrupts the Hsp90-Cdc37 interaction, represses cell proliferation through a strong correlation with the Hsp90-Cdc37 expression level, and selectively down-regulates kinase clients of Hsp90. Synonyms: DDO5936; DDO 5936; 2-(2,4,6-trimethyl-N-(4-((2-(pyrrolidin-1-yl)pyrimidin-4-yl)amino)phenyl)phenylsulfonamido)acetic acid. Grade: >98%. CAS No. 2355377-13-6. Molecular formula: C25H29N5O4S. Mole weight: 495.59.
DDO-5936
DDO-5936 is a potent and specific Hsp90-Cdc37 PPI inhibitor. DDO-5936 can be used for the research of colorectal cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2355377-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139301.
DDO-6600
DDO-6600 is a heat shock protein (Hsp90) inhibitor. DDO-6600 is identified to covalent modification of Cys598 on Hsp90 from in silico study. Synonyms: (E)-1-(3-(3-(3,4-Dimethylphenyl)-1-phenyl-1H-pyrazol-4-yl)acryloyl)piperidine-2-carboxamide. Grade: 99%. CAS No. 2640292-37-9. Molecular formula: C26H28N4O2. Mole weight: 428.53.
D-DOPA
D-DOPA. Group: Biochemicals. Alternative Names: 3-Hydroxy-D-tyrosine; D-3, 4-Di hydroxyphenylalanine; (+) -3- (3, 4-Dihydroxyphenyl) alanine. Grades: Highly Purified. CAS No. 5796-17-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C9H11NO4. US Biological Life Sciences.
A DOPA enantiomer that lacks biological activity. Group: Biochemicals. Alternative Names: 3-Hydroxy-D-tyrosine, D-3, 4-Di hydroxyphenylalanine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
D-dopachrome decarboxylase
This enzyme is specific for D-dopachrome as substrate and belongs to the MIF (macrophage migration inhibitory factor) family of proteins. L-Dopachrome, L- or D-α-methyldopachrome and dopaminochrome do not act as substrates (see also EC 5.3.3.12, L-dopachrome isomerase). Group: Enzymes. Synonyms: phenylpyruvate tautomerase II; D-tautomerase;D-dopachrome tautomerase; D-dopachrome carboxy-lyase. Enzyme Commission Number: EC 4.1.1.84. CAS No. 184111-06-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4833; D-dopachrome decarboxylase; EC 4.1.1.84; 184111-06-6; phenylpyruvate tautomerase II; D-tautomerase;D-dopachrome tautomerase; D-dopachrome carboxy-lyase. Cat No: EXWM-4833.
D-dopachrome decarboxylase (89-97)
D-dopachrome decarboxylase (89-97) is a truncated fragment of D-dopachrome decarboxylase. This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. Synonyms: phenylpyruvate tautomerase II (89-97); D-dopachrome tautomerase (89-97); D-dopachrome carboxy-lyase (89-97).
DDP-38003 trihydrochloride
DDP-38003 trihydrochloride is the trihydrochloride salt of DDP-38003 which is a potent, selective, oral bioavailable irreversible inhibitor of KDM1A. Synonyms: DDP-38003 trihydrochloride; DDP 38003 trihydrochloride; DDP38003 trihydrochloride; N-[4-[(1S,2R)-2-aminocyclopropyl]phenyl]-4-(4-methylpiperazin-1-yl)benzamide; trihydrochloride; DDP-38003 (trihydrochloride). Molecular formula: C21H29Cl3N4O. Mole weight: 459.84.
DDR1-IN-1
DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449685-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13979.
DDR1-IN-1
DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3-fold selectivity over DDR2. Synonyms: DDR1-IN 1; DDR1-IN1; DDR1 IN 1. Grade: 98%. CAS No. 1449685-96-4. Molecular formula: C30H31F3N4O3. Mole weight: 552.59.
DDR1-IN-1 dihydrochloride
DDR1-IN-1 dihydrochloride is a selective discoidin domain receptor 1 (DDR1) tyrosine kinase inhibitor (IC50 = 105 and 413 nM for DDR1 and DDR2, respectively). Synonyms: DDR1 IN 1 dihydrochloride; N-[3-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)oxy]-4-methylphenyl]-4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 1780303-76-5. Molecular formula: C30H31F3N4O3.2HCl. Mole weight: 625.51.
DDR1-IN-1 dihydrochloride
DDR1-IN-1 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DDR1-IN-1 hydrate
DDR-IN-1 has been shown to inhibit colorectal cancer cell lines when used in combination with the PI3K/mTOR inhibitor. DDR1-IN-1 binds to DDR1 and inhibits DDR1 autophosphorylation with an IC50 value of 105 nM and an EC50 value of 87 nM. Synonyms: Discoidin Domain Receptor 1-IN-1. Grade: ≥95%. Molecular formula: C30H31F3N4O3ยท3/4H2O. Mole weight: 566.1.
DDR1-IN-4
DDR1-IN-4 (Compound 2.45) is a selective and potent Discoidin Domain Receptor 1 (DDR1) autophosphorylation inhibitor, with IC50 values of 29 nM and 1.9 μM for DDR1 and DDR2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2125676-13-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114173.
DDR1-IN-5
DDR1-IN-5, a selective Discoidin domain receptor 1 (DDR1) inhibitor (IC50 = 7.36 nM), has anticancer activity. It inhibits the autophosphorylation of DDR1b (Y513) with an IC50 of 4.1 nM. Synonyms: 1,2-Benzisoxazol-3-amine, 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[5-(trifluoromethyl)-3-pyridinyl]-. Grade: ≥95%. CAS No. 2416022-90-5. Molecular formula: C22H13F3N6O. Mole weight: 434.37.
DDR1-IN-6
DDR1-IN-6 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 9.72 nM. DDR1-IN-6 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 9.7 nM. DDR1-IN-6 has anti-cancer activity[1]. DDR1-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416021-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133670.
DDR1-IN-6
DDR1-IN-6, a selective Discoidin domain receptor 1 (DDR1) inhibitor (IC50 = 9.72 nM), has anticancer activity. It inhibits the autophosphorylation of DDR1b (Y513) with an IC50 of 9.7 nM. Synonyms: 1,2-Benzisoxazol-3-amine, 7-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-6-methyl-N-[3-(trifluoromethyl)phenyl]-. CAS No. 2416021-47-9. Molecular formula: C23H14F3N5O. Mole weight: 433.39.
DDR2-IN-1
DDR2-IN-1, a potent DDR2 inhibitor with an IC50 of 26 nM, can be used for osteoarthritis research. Synonyms: 4-(4-((3-(4-chloro-2-(2-(dimethylamino)ethoxy)-5-methylphenyl)ureido)methyl)-2-methylphenoxy)-N-methylpicolinamide; 2-Pyridinecarboxamide, 4-[4-[[[[[4-chloro-2-[2-(dimethylamino)ethoxy]-5-methylphenyl]amino]carbonyl]amino]methyl]-2-methylphenoxy]-N-methyl-. Grade: ≥97%. CAS No. 1573053-23-2. Molecular formula: C27H32ClN5O4. Mole weight: 526.03.
DDR2-IN-1
DDR2-IN-1 is potent DDR2 inhibitor with an IC50 of 26 nM. DDR2-IN-1, compound 129, can be used for osteoarthritis research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1573053-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112545.
DDR-TRK-1
DDR-TRK-1 is a selective inhibitor of Discoidin Domain Receptor 1 (DDR1) (IC50 = 9.4 nM). It also inhibits TRK family. Synonyms: (4R)-N-[3-(4-Methyl-1H-imidazole-1-yl)-5-(trifluoromethyl)phenyl]-2-(5-pyrimidinyl)-4-methyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide; (R)-4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide; DDR1 inhibitor 6j. Grade: ≥95%. CAS No. 1934246-19-1. Molecular formula: C26H23F3N6O. Mole weight: 492.50.
DDT-D8
DDT-D8 is a labelled Dichlorodiphenyltrichloroethane, which is used as an insecticide. Synonyms: 1,1,1-Trichloro-2,2-bis-(4-chlorophenyl-D4) ethane. Grade: 95% by HPLC; 98% atom D. Molecular formula: C14HD8Cl5. Mole weight: 362.525.
DDT-dehydrochlorinase
This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. Group: Enzymes. Synonyms: DDT-ase; 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase; DDTase. Enzyme Commission Number: EC 4.5.1.1. CAS No. 9031-20-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5343; DDT-dehydrochlorinase; EC 4.5.1.1; 9031-20-3; DDT-ase; 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase; DDTase. Cat No: EXWM-5343.
ddTTP
ddTTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddTTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dTTP in cells. Uses: Ddttp is an inhibitor of reverse transcriptases from retroviruse. Synonyms: 2',3'-Dideoxythymidine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 611-60-9. Molecular formula: C10H17N2O13P3 (free acid). Mole weight: 466.17 (free acid).
ddTTP-α-S
ddTTP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-48-9. Molecular formula: C10H17N2O12P3S (free acid). Mole weight: 482.2 (free acid).