A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
DBZ, also called dibenzazepine, is a γ-secretase inhibitor to treat Alzheimer's Disease, and it also inhibits Notch signaling. Synonyms: YO-01027; YO 01027; YO01027; (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide; dibenzazepine; GSI XX; Dibenzazepine; 209984-56-5; YO-01027; (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide; Deshydroxy LY 411575; gamma-Secretase Inhibitor XX; DBZ; 209984-56-5 pound not YO 010. Grade: >98%. CAS No. 209984-56-5. Molecular formula: C26H23F2N3O3. Mole weight: 463.48.
DBZ
DBZ. Group: Biochemicals. Grades: Purified. CAS No. 209984-56-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DC-009
DC-009 is a small-molecule thrombolytic that can scavenge the free radical in cells. Studies in vitro and in vivo showed that DC-009 had the similar activity as recombinant tissue plasminogen activator (rt-PA) and dose-dependent activity. Further study of treating ischemic stroke is planned. Uses: The potential treatment of ischemic stroke. Synonyms: DC009; DC 009.
DC-05
DC-05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 10.3 uM. It has significant selectivity toward other AdoMet-dependent protein methyltransferases. It significantly inhibits cancer cell proliferation. It inhibitis DNMT1 by binding to DNMT1 instead of incorporating into DNA. Uses: Dc-05 inhibits cancer cell proliferation. Synonyms: DC-05; DC 05; DC05; 1-Carbazol-9-yl-3-[2-(1H-indol-3-yl)ethylamino]propan-2-ol. Grade: >98 %. CAS No. 890643-16-0. Molecular formula: C25H25N3O. Mole weight: 383.49.
DC-05
DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 10.3 μM and 1.09 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 890643-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12746.
DC07090 dihydrochloride
DC07090 dihydrochloride is a potent, reversible, low toxicity and competitive non-peptide inhibitor of human enterovirus 71 3C protease with an IC50 and a Ki value of 21.72 μM and 23.29 μM. It also inhibits the replication of coxsackievirus A16 (CVA16) with an EC50 value of 27.76 μM. Synonyms: 2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2); (4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)(pyridin-2-ylmethyl)amine dihydrochloride; (4-Oxazolo[4,5-b]pyridin-2-yl-phenyl)-pyridin-2-ylmethyl-amine Dihydrochloride. Grade: >98%. CAS No. 1158264-37-9. Molecular formula: C18H16Cl2N4O. Mole weight: 375.25.
DC1
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an ADC cytotoxic for the targeted treatment of cancer. Synonyms: (S)-N-(2-(1-(Chloromethyl)-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)-1H-indol-5-yl)-5-(3-mercaptopropanamido)-1H-indole-2-carboxamide; 1H-Indole-2-carboxamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-5-yl]-5-[(3-mercapto-1-oxopropyl)amino]-; N-(2-{[(1S)-1-(Chloromethyl)-5-hydroxy-1,2-dihydro-3H-benzo[e]indol-3-yl]carbonyl}-1H-indol-5-yl)-5-[(3-sulfanylpropanoyl)amino]-1H-indole-2-carboxamide. Grade: ≥95%. CAS No. 169901-27-3. Molecular formula: C34H28ClN5O4S. Mole weight: 638.14.
DC-1
DC-1 is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. Synonyms: (S)-5-amino-N-(2-(1-(chloromethyl)-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)-1H-indol-5-yl)-1H-indole-2-carboxamide. Grade: ≥95%. Molecular formula: C31H24ClN5O3. Mole weight: 550.01.
DC-102
DC-102 is produced by the strain of Streptomyces sp. It has anti-gram-positive bacteria activity and anti-tumor effect. Synonyms: DC 102 Antibiotic; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-7-((4,6-dideoxy-3-C-methyl-4-(methylamino)-alpha-L-mannopyranosyl)oxy)-11-methoxy-2-propylidene-. CAS No. 115722-50-4. Molecular formula: C24H35N3O6. Mole weight: 461.55.
DC10SMe
DC10SMe is a DNA alkylating agent useful in the synthesis of antibody drug conjugates (ADCs). DC10SMe has IC50 values of 15 pM, 12 pM and 12 pM against Ramos, Namalwa and HL60/s cancer cells, respectively. Synonyms: DC10SMe; CHEMBL2158589; AKOS040732934; HY-135122; CS-0109488. Molecular formula: C35H29N5O4S2. Mole weight: 647.77.
DC-120
DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increasing terminal deoxynucleotidyl transferasedUTP nick-end labeling-positive cells in the tumor sample. Synonyms: DC-120; DC 120; DC120. Grade: 98%. CAS No. 1261080-40-3. Molecular formula: C18H18Cl2N6OS. Mole weight: 437.35.
DC260126
DC260126 is a potent antagonist of GPR40 (FFAR1). DC260126 dose-dependently inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic acid, oleic acid, palmitoleic acid and lauric acid (IC50: 6.28, 5.96, 7.07, 4.58 μM, respectively)[1]. DC260126 could protect MIN6 β cells from palmitate-induced ER stress and apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 346692-04-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101906.
DC 260126
DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist that decreases intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. It was shown to lower serum insulin levels, improve insulin sensitivity and reduces the rate of apoptotic pancreatic β cells in obese diabetic (db/db) rats. Synonyms: DC 260126; DC260126; DC-260126; N-(4-Butylphenyl)-4-fluorobenzenesulfonamide. Grade: ≥98% by HPLC. CAS No. 346692-04-4. Molecular formula: C16H18FNO2S. Mole weight: 307.38.
DC 260126
DC 260126. Group: Biochemicals. Grades: Purified. CAS No. 346692-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DC41
DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. Synonyms: DC41; 1354787-69-1; AKOS040732937; HY-112901; CS-0067648; N-{2-[(1S)-1-(chloromethyl)-5-hydroxy-1H,2H,3H-benzo[e]indole-3-carbonyl]-1H-indol-5-yl}-5-(4-methyl-4-sulfanylpentanamido)-1H-indole-2-carboxamide. CAS No. 1354787-69-1. Molecular formula: C37H34ClN5O4S. Mole weight: 680.21.
DC41-SMe
DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer. CAS No. 1354787-71-5. Molecular formula: C38H36ClN5O4S2. Mole weight: 726.31.
DC-5163
DC-5163 is a potent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with an IC50 of 176.3 nM and a Kd of 3.192 μM. DC-5163 can inhibit glycolysis pathway partially. DC-5163 also selectively inhibits cancer cell proliferation and induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 897771-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-43643.
DC_517
DC_517 is a novel selective non-nucleoside inhibitor of DNMT1. (IC50 = 1.7 μM), was found to be more potent than DC_05. Uses: A novel selective non-nucleoside inhibitor. Synonyms: DC-517; DC 517; DC517; 1-{[1,3-Di(9H-carbazol-9-yl)-2-propanyl]oxy}-3-(isopropylamino)-2-propanol. Grade: ≥98%. CAS No. 500017-70-9. Molecular formula: C33H35N3O2. Mole weight: 505.65.
DC661
DC661 is an effective palmitoyl-protein thioesterase 1 (PPT1) inhibitor that inhibits autophagy and ACTS as an antilysosomal agent. Compared with hydroxychloroquine (HCQ), DC661 has significant acid hydrolysis and autophagy inhibition. Synonyms: DC661; 1872387-43-3; N-(7-chloroquinolin-4-yl)-N'-[6-[(7-chloroquinolin-4-yl)amino]hexyl]-N'-methylhexane-1,6-diamine; N1-(7-chloroquinolin-4-yl)-N6-(6-((7-chloroquinolin-4-yl)amino)hexyl)-N6-methylhexane-1,6-diamine; dc-661; C31H39Cl2N5; CHEMBL4873725; SCHEMBL19399303; BCP30743; EX-A2963; XZC38743; s8808; ZB1540; AKOS037649041; DC-661; DC 661; AC-35596; BS-16368; HY-111621; CS-0088759; D80814; 7-chloro-N-[6-({6-[(7-chloroquinolin-4-yl)amino]hexyl}(methyl)amino)hexyl]quinolin-4-amine. CAS No. 1872387-43-3. Molecular formula: C31H39Cl2N5. Mole weight: 552.58.
DC661
DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1872387-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111621.
DC 81
DC 81 is originally isolated from Streptomyces roseiscleroticus DO-81. It has weak anti-gram-positive, anti-gram-negative and tumor activity. Synonyms: Antibiotic DC 81; (+)-1,2,3,11a-Tetrahydro-8-hydroxy-7-methoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one; 7-Methoxy-8-hydroxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 8-hydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one. CAS No. 81307-24-6. Molecular formula: C13H14N2O3. Mole weight: 246.26.
DC 838
DC 838 is a potent human cyclophilin A (CypA) inhibitor. Synonyms: DC 838; DC838; DC-838; 1-N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]-3-N,3-N-diethylpiperidine-1,3-dicarboxamide. Grade: 99%. CAS No. 508186-08-1. Molecular formula: C27H29N5O4. Mole weight: 487.55.
DC 86M
It is originally isolated from Streptomyces lugeogriseus 86. DC 86M has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and can inhibit mouse sarcoma 180 cells. Synonyms: 6-(1-((Hydroxyacetyl)oxy)ethyl)-1-phenazinecarboxylic acid; DC-86-M; DC-86M; DC 86 M; 6-{1-[(Hydroxyacetyl)oxy]ethyl}phenazine-1-carboxylic acid. Grade: >98%. CAS No. 94448-15-4. Molecular formula: C17H14N2O5. Mole weight: 326.30.
DC92-B
It is originally isolated from Actinomadura sp. DC92-B is mainly resistant to Gram-positive bacteria, and it also has anti-tumor activity. Synonyms: DC 92B; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 11-hydroxy-5-methyl-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D-arabino-hexopyranosyl)-10-(2,3,6-trideoxy-3-(dimethylamino)-5-C-hydroxy-3-C-methylhexopyranosyl)-2-(3,3',3'-trimethyl(2,2'-bioxiran)-3-yl)-. Grade: >98%. CAS No. 116988-30-8. Molecular formula: C42H52N2O12. Mole weight: 776.87.
DC92-D
It is originally isolated from Actinomadura sp. and DC92-D is mainly resistant to Gram-positive bacteria. Synonyms: DC 92D; 8-(4-(dimethylamino)-3-hydroxy-2-methyl-3,4-dihydro-2H-pyran-6-yl)-10-(3-(dimethylamino)-4,6-dihydroxy-3,6-dimethyltetrahydro-2H-pyran-2-yl)-11-hydroxy-5-methyl-2-(3,3',3'-trimethyl-[2,2'-bioxiran]-3-yl)-4H-naphtho[2,3-h]chromene-4,7,12-trione. CAS No. 116988-29-5. Molecular formula: C42H50N2O12. Mole weight: 774.85.
DCA
DCA is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. DCA also induces apoptosis and reverses the KV1.5 channels downregulation in cancer. Synonyms: Sodium dichloroacetate; Sodium 2,2-dichloroacetate; Dichloroacetic acid sodium salt. CAS No. 2156-56-1. Molecular formula: C2HCl2NaO2. Mole weight: 150.92.
dC(Ac)-3'-PS Phosphoramidite
dC(Ac)-3'-PS Phosphoramidite is a cytidine-derived phosphoramidite designed for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, providing enhanced nuclease resistance and improved biological stability to the resulting oligonucleotides. The cytosine base is protected with an acetyl (Ac) group at the N4 position to prevent unwanted side reactions during synthesis. This phosphoramidite is widely used in therapeutic applications, such as antisense oligonucleotides and siRNA, where increased stability, resistance to enzymatic degradation, and prolonged activity are critical for performance. Synonyms: 5'-DMT-dC(Ac)-3'-PS-Phosphoramidite; Cytidine, N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Cytidine, N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; dC(Ac) ThioPhosphamidite. Grade: ≥90%. Molecular formula: C45H49N4O8PS2. Mole weight: 869.00.
DC_AC50
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 497061-48-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-107636.
dC(Ac)-CE-Reverse Phosphoramidite
dC(Ac)-CE-Reverse Phosphoramidite is a cytidine-derived phosphoramidite designed for the reverse incorporation of nucleotides during oligonucleotide synthesis. It features a 3'-cyanoethyl (CE) phosphoramidite group at the 5'-position, enabling the addition of nucleotides in the reverse (3'→5') direction instead of the conventional 5'→3' direction. The cytosine base is protected with an acetyl (Ac) group at the N4 position to prevent side reactions during synthesis. This reverse phosphoramidite is commonly used for specialized oligonucleotide designs, such as branched structures, probes, and complex synthetic constructs, where reverse polarity is required for functionality or stability. Synonyms: 3'-DMT-dC(Ac)-CE Reverse; Cytidine, N-acetyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Acetyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-5'-cyanoethyl phosphoramidite; ((2R,3S,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; 3'-O-DMTr-dC(Ac)-CE-Reverse-Phosphoramidite; DNA C(Ac) 3'-DMTr 5'-amidite. Grade: ≥98%. CAS No. 1632243-18-5. Molecular formula: C41H50N5O8P. Mole weight: 771.84.
DCAF15 ligand-1
DCAF15 ligand-1 (compound 9) is a ligand for the E3 ligase DCAF15. DCAF15 ligand-1 can be used in the synthesis of IBG1 (HY-153459)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098346-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W037495.
DCAF1 binder 1
DCAF1 binder 1 is a selective for the CRL4 DCAF1 E3 ligase complex. DCAF1 binder 1 is a ligands for E3 Ligase, involving in targeted protein degradation (TPD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053860-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149934.
D-Calcium Pantothenate, 98.0-101.0% USP/EP/FCC
D-Calcium Pantothenate, 98.0-101.0% USP/EP/FCC. Group: Biochemicals. Grades: USP. Pack Sizes: 25g, 100g, 1Kg, 5Kg, 10Kg. US Biological Life Sciences.
Worldwide
D-Calcium Pantothenate USP
D-Calcium Pantothenate USP.
CA, FL & NJ
D-(+)-Camphor
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks. Formula: C10H16O. CAS No. 464-49-3. Prepack ID 54189554-100g. Molecular Weight 152.23. See USA prepack pricing.
D-(+)-Camphor
D-camphor appears as colorless or white crystals. Sublimes. Flash point 149°F. Burns readily with a bright, smoky flame. Penetrating aromatic odor. Pungent, aromatic taste followed by a sensation of cold. (NTP, 1992);White to gray translucent crystals or fused mass; Warm, minty, almost ethereal diffusive aroma;White to pale yellow crystalline solid, Camphoraceous aroma. CAS No. 464-49-3. Molecular formula: C10H16O. Mole weight: 152.23g/mol. IUPAC Name: (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one. SMILES: CC1(C2CCC1(C(=O)C2)C)C. InChI: InChI=1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m1/s1.
D-CAMPHOR
D-CAMPHOR. CAS No. 464-49-3. Product ID: CDC10-0574. Molecular formula: C10H16O. Category: Lip protectants. Product Keywords: Cosmetic Ingredients; Active Ingredients; Lip protectants; D-CAMPHOR; CDC10-0574; 464-49-3; C10H16O; 207-355-2; 464-49-3. Purity: 0.99. Color: White. EC Number: 207-355-2. Physical State: Crystals. Solubility: Slightly soluble in water, very soluble in alcohol and in light petroleum, freely soluble in fatty oils, very slightly soluble in glycerol. Storage: 2-8°C. Boiling Point: 204 °C. Melting Point: 178-182 °C (lit.).
DCAP
DCAP is a broad-spectrum antibiotic targeting the membranes of both Gram-positive and Gram-negative bacteria. DCAP blocks autophagy at the late stages by preventing autophagolysosome maturation and interrupting the autophagic flux[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU0607402. CAS No. 500015-20-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136068.
D-Carnitine
D-Carnitine is used as a building block for antidiabetic, microbicidal compounds. Group: Coenzymes. CAS No. 541-14-0. Purity: >96%. Mole weight: 161.2. Form: Solid. D-Carnitine; 541-14-0. Cat No: COEC-102.
D-Carnitine
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 541-14-0. Pack Sizes: 10 mM * 1 mL in Water; 250 mg; 1 g. Product ID: HY-W012550.
D-Carnitine
Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. Group: Biochemicals. Alternative Names: (2S)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium Inner Salt; D- (3-Carboxy-2-hydroxypropyl) trimethyl Ammonium Hydroxide Inner Salt; (+)-Carnitine; (+)-D-Carnitine; D-(+)-Carnitine; d-Carnitine. Grades: Highly Purified. CAS No. 541-14-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
D-Carnitine hydrochloride 99+%
D-Carnitine hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 10017-44-4. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
d(+)-Carnitinenitrile chloride,97
d(+)-Carnitinenitrile chloride,97. Alternative Names: (3-cyano-2-hydroxypropyl)trimethyl-,chloride,d-ammoniu;3-cyano-2-hydroxy-n,n,n-trimethyl-,chloride,(s)-1-propanaminiu;d-(3-cyano-2-hydroxypropyl)trimethylammoniumchloride;d-carnitinnitrilchlorid;D(+)-CARNITINENITRILE CHLORIDE, 97. CAS No. 1116-95-6. Product ID: ACM1116956. Molecular formula: C7H15ClN2O. Mole weight: 178.6598. Alfa Chemistry - ISO 9001:32057 Certified.
D-(+)-Carvone
D-(+)-Carvone, is used for the synthesis of (-)-terpestacin, a fungal metabolite with anticancer activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 2244-16-8. Pack Sizes: 10g, 25 g. Molecular Formula: C10H14O. US Biological Life Sciences.
Worldwide
D-Cateslytin
D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM). D-Cateslytin can rapidly enter C. albicans, and shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3002053-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11170.
DCB
DCB is an allosteric ligand for the metabotropic glutamate receptor mGlu5 that displays neutral modulation. It inhibits the modulation of mGlu5 by other allosteric modulators without affecting agonist-stimulated mGlu5 responses. Synonyms: [(3-Chlorophenyl)methylene]hydrazone-3-chlorobenzaldehyde; (E,E)-Bis[(3-chlorophenyl)methylidene]hydrazine. Grade: ≥98% by HPLC. CAS No. 6971-97-7. Molecular formula: C14H10Cl2N2. Mole weight: 277.15.
DCB
DCB. Group: Biochemicals. Grades: Purified. CAS No. 6971-97-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
dCBP-1
dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and ablates oncogenic enhancer activity driving MYC expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2484739-25-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134582.
dC(Bz)-3'-PS Phosphoramidite is a cytidine-derived phosphoramidite used for synthesizing oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The cytosine base is protected with a benzoyl (Bz) group at the N4 position to prevent side reactions during synthesis. This phosphoramidite is particularly useful in therapeutic oligonucleotides, such as antisense and siRNA applications, where improved stability, enzymatic resistance, and prolonged biological activity are essential. Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; dC(Bz) ThioPhosphamidite; 5'-DMT-dC(Bz)-3'-PS-Phosphoramidite. Grade: ≥90%. CAS No. 178272-25-8. Molecular formula: C50H51N4O8PS2. Mole weight: 931.07.
DCC-2618
DCC-2618 inhibits normal and mutant KIT kinase at the nanomol level. The targets are wt c-KIT, c-KIT mutants, PDGFR alpha, PDGFR beta, KDR and cFMS. DCC-2618 inhibits mutant KIT in GIST patient cell line (GIST T1 pKIT western Ex11 deletion) at a IC 50 of 2 nM. Deciphera's technology has identified DCC-2618 as a molecule which can be developed as second line therapy for imatinib and sunitinib resistant GIST patients with the potential to progress to frontline GIST therapy. DCC-2618 has been designed to effectively inhibit the imatinib and sunitinib-sensitive KIT juxtamembrane domain mutants (JMD) as well as secondary resistant KIT kinase-domain mutants. DCC-2618 additionally targets PDGFR alpha oncogenic mutants. Synonyms: DCC2618; DCC 2618; c-Kit-IN-1; PDGFR inhibitor 1; N-[2,5-Difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide. Grade: >98%. CAS No. 1225278-16-9. Molecular formula: C26H21F2N5O3. Mole weight: 489.47.
DCC-3116
DCC-3116 is an orally active ULK1/2 inhibitor. DCC-3116 can inhibit autophagy in lung cancer cells by inhibiting KRASG12C signaling, thereby inhibiting the proliferation of lung cancer cells and exerting anti-cancer effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2543673-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-160699.
DC_C66
DC_C66 is a selective and cell-permeable coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. It shows good selectivity for CARM1 against PRMT1 (IC50 = 21 μM), PRMT6 (IC50 = 47 μM) and PRMT5. Synonyms: 9-(ethoxycarbonyl)-11H,12H-dibenzo[f,h]isoquino[2,1-b]isoquinolinium; 9-(Ethoxycarbonyl)-11,12-dihydrodibenzo[f,h]isoquinolino[2,1-b]isoquinolinium; Benzo[a]phenanthro[9,10-g]quinolizinium, 9-(ethoxycarbonyl)-11,12-dihydro-. Grade: ≥95%. CAS No. 108181-00-6. Molecular formula: C28H22NO2+. Mole weight: 404.48.
DC-cholesterol-d7
DC-cholesterol-d7. Alternative Names: 3β-[N-(N',N'-dimethylaminoethane)-carbamoyl]cholesterol(d7) hydrochloride. CAS No. 3056013-52-3. Purity: >99%. Product ID: ALCFA3056013523. Molecular formula: C32H50D7ClN2O2. Mole weight: 544.31. Alfa Chemistry - ISO 9001:32057 Certified.
DC-Chol hydrochloride
DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DC-Cholesterol hydrochloride. CAS No. 166023-21-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-137131.
DC-Chol Liposome
DC-Chol is synthesized from N',N'-dimethylethylenediamine and chloroformylated cholesterol. This liposome is prepared with DC-Chol, which can be used as adjuvant. It combination with genetically engineered hepatitis B surface antigen increases the levels of specific antibodies IgG1, IgG2a and Th1 and Th2 class cytokines. It is only for research purposes. Group: Liposomal vaccine or adjuvant.
DCC(NN"-Dicyclohexylcarbodiimide)
DCC(NN"-Dicyclohexylcarbodiimide). CAS No: 538-75-0
Sarchem Laboratories New Jersey NJ
DCEBIO
DCEBIO is a small/medium conductance calcium-activated potassium (SKCa/IKCa) channel opener and primary neuron signal blocker. It hyperpolarizes the membrane potential of C2C12 myoblasts by activating IKCa channels, thereby promoting myogenic differentiation. The specific biological activity of DCEBIO is manifested in increased myotube formation, enhanced myosin heavy chain II protein levels and myogenin mRNA levels. DCEBIO can be applied in the field of muscle research, especially in muscle-related degenerative diseases such as sarcopenia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 60563-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102052.
DCEBIO
DCEBIO is a Ca2+ sensitive K+ channel (SKCa) agonist stimulating Cl- secretion via activation of hKCa3.1 (IK1) potassium channels and activation of an apical Cl- conductance. Synonyms: 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one; Dichloro-EBIO. Grade: ≥99% by HPLC. CAS No. 60563-36-2. Molecular formula: C9H8Cl2N2O. Mole weight: 231.08.
DCEBIO
DCEBIO. Group: Biochemicals. Grades: Purified. CAS No. 60563-36-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
D-Cellobial
D-Cellobial is an exquisite and groundbreaking compound profoundly employed for the research of assorted maladies, encompassing the intricate realms of cancer and diabetes. This prodigious asset acts as an unparalleled inhibitor, thwarting the nefarious activity of meticulously targeted enzymes intricately intertwined within the metabolic cascades. Synonyms: 1,5-Anhydro-2-deoxy-4-(O-b-D-glucopyranosyl)-D-arabino-hex-1-enitol; D-arabino-Hex-1-enitol, 1,5-anhydro-2-deoxy-4-O-beta-D-glucopyranosyl-; 1,2-Dideoxy-4-O-beta-D-glucopyranosyl-D-arabino-hex-1-enopyranose; D-cellobiosene. Grade: ≥98%. CAS No. 490-51-7. Molecular formula: C12H20O9. Mole weight: 308.28.
D-Cellobiose, an imperative disaccharide formed by coupling two glucose molecules, finds extensive utility in the biomedical sector. This compound assumes the role of a crucial substrate in enzyme assays, thereby facilitating their efficacy. Moreover, it serves as a vital carbon source for bacteria engrossed in the degradation of cellulose. Synonyms: Glc-b-1,4-Glc; 4-O-(b-D-Glucopyranosyl)-D-glucopyranose; 4-O-β-D-Glucopyranosyl-D-glucose; Glc1-b-4-D-Glc; D-(+)-Cellobiose; beta-maltose; 1-beta-D-Glucopyranosyl-4-D-glucopyranose; Glc(b1-4)aldehydo-Glc; Cellobiose; D-(+)-Cellobiose; Cellobiose 90; Cellose; Sun Cellobio K. Grade: ≥98%. CAS No. 528-50-7. Molecular formula: C12H22O11. Mole weight: 342.30.
D-(+)-Cellobiose
D-(+)-Cellobiose. Group: Molecular Biology. Grades: Highly Purified. CAS No. 528-50-7. Pack Sizes: 5g, 25g. Molecular Formula: C12H22O11. US Biological Life Sciences.
Worldwide
D-(+)-Cellobiose
25g Pack Size. Group: Sugars. Formula: C12H22O11. CAS No. 528-50-7. Prepack ID 13810609-25g. Molecular Weight 342.3. See USA prepack pricing.
D-Cellobiose-[1-13C]
D-Cellobiose-[1-13C] is the isotope labelled edtion of D-Cellobiose, like any other stable isotopical D-Cellobiose, a diasccharide consisting of two glucose. Synonyms: D-Cellobiose-1-13C; [1-13C]cellobiose; D-[1-13C]cellobiose. Molecular formula: C11[13C]H22O11. Mole weight: 343.29.
D-Cellobiose-[1'-13C]
D-Cellobiose-[1'-13C] is intended for use as an internal standard for the quantification of D-Cellobiose, a diasccharide consisting of two glucose. Synonyms: D-Cellobiose-1'-13C; [1'-13C]cellobiose; D-[1'-13C]cellobiose. CAS No. 2892630-35-0. Molecular formula: C11[13C]H22O11. Mole weight: 343.29.
D-Cellobiose-[13C12]
D-Cellobiose-[13C12] is the deuterium labelled form of D-Cellobiose, and D-Cellobiose is a disaccharide that consists of two β-glucose molecules linked by a β-1,4 glycosidic bond. It can be used as a substrate of β-glucosidase. Synonyms: [UL-13C12]cellobiose; 4-O-beta-D-[UL-13C6]glucopyranosyl-D-[UL-13C6]glucose; cellobiose-U-13C12; beta-D-[1-13C]glucopyranosyl-(1-4)-D-[1-13C]glucose. Molecular formula: [13C]12H22O11. Mole weight: 354.20.
D-Cellobiose-13C6
D-Cellobiose-13C6 is the deuterium labelled analogue of D-Cellobiose (C255000), which is a disaccharide of two glucose molecules in a beta 1-4 linkage. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C613C6H15O11, Molecular Weight: 341.2. US Biological Life Sciences.
Worldwide
D-(+)-Cellobiose Octaacetate
D-(+)-Cellobiose Octaacetate is a compound often used in the biomedical industry serving as a precursor for various drugs development. Synonyms: D-Glucopyranose, 4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-, 1,2,3,6-tetraacetate; 4-O-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)-D-glucopyranose 1,2,3,6-Tetraacetate; Octa-O-acetylcellobiose; Octaacetyl-D-cellobiose; Cellobiose Octaacetate. Grade: 98%. CAS No. 3616-19-1. Molecular formula: C28H38O19. Mole weight: 678.59.