A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
D-Aspartic acid sodium salt. Group: Biochemicals. Alternative Names: Sodium D-aspartate. Grades: Highly Purified. CAS No. 10329-81-4. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C4H6NO4·Na. US Biological Life Sciences.
Worldwide
DAT-230
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230-treatment in HT-1080 cells resulted in microtubule de-polymerization and G2/M phase arrest preceding apoptosis. Phosphor-cdc2 (thr14/tyr15) reduction, cyclin B1 accumulation and aberrant spindles denoted the cyclin B1-cdc2 complex active and M phase arrest in HT-1080 cells treated with DAT-230. Apoptosis induced by DAT-230 was related with the activation of caspase-9, caspase-3 and PARP cleavage, which were at the downstream of mitochondria. The decrease ratio of Bcl-2/Bax, elevation of NO and disruption of ΔΨm confirmed the causal relationship between DAT-230 and mitochondrial pathway. In vivo, DAT-230 delayed tumor growth, induced tumor perfusion decrease and extensive hemorrhagic-necrosis. Synonyms: DAT 230; DAT230. Grade: 98%. CAS No. 1504583-00-9. Molecular formula: C22H20BrN3O2S. Mole weight: 339.45.
D-Atabrine dihydrochloride
D-Atabrine dihydrochloride is an active enantiomer of quinacrine, which displays antiprion activity. Synonyms: (4S)-N4-(6-Chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-1,4-pentanediamine dihydrochloride; 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, (4S)-, hydrochloride (1:2); (S)-quinacrine dihydrochloride. Grade: ≥95%. CAS No. 56100-41-5. Molecular formula: C23H32Cl3N3O. Mole weight: 472.88.
Datelliptium chloride
Datelliptium chloride, derived from ellipticine, is a DNA-intercalating agent with good activity in murine tumor models over a broad range of doses. Synonyms: 2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol; chloride; 2-(diethylamino-2-ethyl)-9-hydroxyellipticinium; 2-DEHE; datelliptium chloride; detalliptinium; detalliptinium acetate salt; detalliptinium chloride; detalliptium acetate; diethylaminoethyl-2-OH-9-ellipticinium; NSC 311152; NSC 626718X; NSC-311152; SR 95156A; SR 95156B; SR-95156A. CAS No. 105118-14-7. Molecular formula: C23H28ClN3O. Mole weight: 397.94.
Datelliptium chloride hydrochloride
Datelliptium chloride hydrochloride, a DNA-intercalating agent derived from Ellipticine, is effective against a variety of mouse solid tumors in vivo. Synonyms: 2-(2-(Diethylamino)ethyl)-9-hydroxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium chloride hydrochloride; 6H-Pyrido[4,3-b]carbazolium, 2-[2-(diethylamino)ethyl]-9-hydroxy-5,11-dimethyl-, chloride, hydrochloride (1:1:1). Grade: ≥95%. CAS No. 157000-76-5. Molecular formula: C23H29Cl2N3O. Mole weight: 434.40.
DATEM-E472e
Diacetyl tartaric acid esters of mono- and diglycerides of fatty acids, or simply DATEM, is an emulsifier used in breadmaking to strengthen the dough structure so that it can successfully expand during proofing and baking. Synonyms: DATEM---E472e;Diacetyl tartaric acid monodiglyceride;Acetylated single (double) glycerol fatty acid ester. CAS No. 977051-29-8. Product ID: CDF4-0258. Category: It is used in bread, buns and many other yeast-leavened bakery products at levels of 0.2-0.6% (based on flour weight). DATEM possesses excellent dough strengthening properties due to its ability to adsorb at the gas/liquid interface of dough and stabilize the foam structure trapped by the gluten matrix and prevent gas bubble coalescence.1,2 So, DATEM enhances gas (CO3) retention and improves tolerance to shocks in case of mechanical abuse during final proofing and baking. Due to its anionic nature, DATEM also has the capacity to interact with gluten proteins, promoting protein aggregation. Product Keywords: Food Emulsifiers; CDF4-0258; DATEM-E472e; 977051-29-8; DATEM---E472e;Diacetyl tartaric acid monodiglyceride;Acetylated single (double) glycerol fatty acid ester. Chemical Name: Diacety Tartaric Acid Esters of Mono & Diglycerides. Grade: Food grade. Stability and Storage Conditions: Prevent from moisture and caking. Sealed and stored in the low temperature, dry, cool and well-ventilated place. Forbid storing and transporting with
Date Palm Fruit (Phoenix Dactylifera) Powder
Date Palm Fruit (Phoenix Dactylifera) Powder.
CA, FL & NJ
Date Palm Pollen P.E. 4:1
Date Palm Pollen P.E. 4:1.
CA, FL & NJ
Date Palm Seed P.E. 4:1
Date Palm Seed P.E. 4:1.
CA, FL & NJ
dA-Thiophosphoramidite
dA-Thiophosphoramidite, a widely utilized chemical compound in the biomedical sector, is an imperative tool employed to fabricate chemically modified oligonucleotides and investigate the complexities of nucleic acids structure and biology. Furthermore, it holds significant value in designing therapeutic medications that selectively target genes responsible for the onset of malignant neoplasms and viral infections. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C51H51N6O7PS2. Mole weight: 955.09.
Datiscetin (compound 5) is a natural compound isolated from the cultivar Roland, and shows fungitoxic activity towards F. oxysporum f. sp. dianthi.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 480-15-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8722.
Datopotamab
Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2267989-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99843.
Datopotamab deruxtecan
Datopotamab deruxtecan is an antibody-drug conjugate consisting of a humanized anti-TROP2 IgG1 monoclonal antibody conjugated to a potent topoisomerase I inhibitor payload via a stable tetrapeptide-based cleavable linker. Synonyms: DS-1062; DS-1062A; Dato-DXd. CAS No. 2238831-60-0.
Datopotamab deruxtecan
Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC. Alternative Names: DS-1062, DS-1062A, Anti-TRP2/dxd. CAS No. 2238831-60-0. Pack Sizes: 1mg. Product ID: D4050. Formula: 4.2. Storage Conditions: Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Datopotamab deruxtecan (solution)
Datopotamab deruxtecan (DS-1062) solution is a TROP2-targeted antibody-drug conjugate (ADC) with human TROP2 Kd of 0.74 nmol/L. Datopotamab deruxtecan solution consists of the antibody Datopotamab (HY-P99843) and the toxic molecule-linker conjugate Deruxtecan (HY-13631E). Datopotamab deruxtecan solution binds TROP2, triggers internalization and lysosomal trafficking and releases DXd topoisomerase I inhibitor payload. Datopotamab deruxtecan solution disrupts DNA function, induces DNA damage, apoptosis, and bystander killing of tumor microenvironment cells. Datopotamab deruxtecan solution can be used in research related to triple-negative breast cancer, gastric cancer, and non-small cell lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DS-1062 (solution); Dato-DXd (solution). CAS No. 2238831-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141598.
dATP
dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Synonyms: 2'-Deoxyadenosine-5'-Triphosphate. Grade: ≥ 95% by HPLC. CAS No. 1927-31-7. Molecular formula: C10H16N5O12P3. Mole weight: 491.18.
dATPαS
dATPαS is a modified nucleotide analog that is widely used as a substrate for various DNA polymerases. It is commonly used in DNA labeling experiments due to its incorporation into target DNA by polymerases during DNA synthesis. It has also been used to generate non-cleavable modified DNA for studying DNA repair mechanisms. Synonyms: 2'-Deoxyadenosine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95% by HPLC. CAS No. 64145-28-4. Molecular formula: C10H16N5O11P3S (free acid). Mole weight: 507.24 (free acid).
dATP(dGTP)-DNA purinetransferase
The purine residue is transferred on to the apurinic site forming a normal glycosylic bond. dATP reacts at sites of the double-stranded depurinated DNA that lack adenine, and dGTP at sites that lack guanine. Group: Enzymes. Enzyme Commission Number: EC 2.6.99.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2942; dATP(dGTP)-DNA purinetransferase; EC 2.6.99.1. Cat No: EXWM-2942.
dATP solution - Lithium Salt
The lithium salt solution form of dATP. dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid).
dATP solution - Sodium Salt
The sodium salt solution form of dATP. dATP is a purine nucleoside triphosphate used in the synthesis of DNA by being incorporated into DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O12P3 (free acid). Mole weight: 491.18 (free acid).
Datucin
Datucin is an antibacterial peptide isolated from Datura stramonium. It has activity against fungi. Synonyms: Thr-Phe-Pro-Lys-Cys-Ala-Pro-Thr-Arg-Pro-Pro-Gly-Pro-Lys-Pro-Cys-Asp-Ile-Asn-Asn-Phe-Lys-Ser-Lys-Phe-Trp-His-Ile-Trp-Arg-Ala. Grade: 96.7%.
Daturabietatriene
Daturabietatriene is isolated from the heartwoods of Pinus yunnanensis. Synonyms: Abieta-8,11,13-triene-15,18-diol. Grade: 96.5%. CAS No. 65894-41-9. Molecular formula: C20H30O2. Mole weight: 302.5.
DAU 5884 hydrochloride
DAU 5884 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 131780-48-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DAU 5884 hydrochloride
DAU 5884 hydrochloride is a selective muscarinic M3 receptor antagonist. It inhibits methacholine-dependent effects on cell proliferation and muscle contractility in bovine tracheal smooth muscle. Synonyms: DAU 5884 hydrochloride; DAU5884 hydrochloride; DAU-5884 hydrochloride; 8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro-2-oxo-3(2H)-quinazolinecarboxylic acid ester hydrochloride; [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride. Grade: ≥99% by HPLC. CAS No. 131780-48-8. Molecular formula: C17H21N3O3.HCl. Mole weight: 351.83.
Daucosterol
Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eleutheroside A; β-Sitosterol β-D-glucoside. CAS No. 474-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0410.
DAUDA
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 73025-02-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-120959.
Daun02
Daun02 is a proagent of the topoisomerase inhibitor Daunorubicin. Uses: Scientific research. Category: Signaling pathways. CAS No. 290304-24-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13061.
Daun02
Daun02 is a daunorubicin b-galactoside prodrug for use in conjunction. Uses: Adcs cytotoxin. Synonyms: Daun 02; Daun-02; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[({[4-(β-D-galactopyranosyloxy)-3-nitrobenzyl]oxy}carbonyl)amino]-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-(β-D-galactopyranosyloxy)-3-nitrophenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-; N-[4''-(β-Galactopyranosyl)-3''-nitrobenzyloxycarbonyl]daunomycin. Grade: >98%. CAS No. 290304-24-4. Molecular formula: C41H44N2O20. Mole weight: 884.79.
Daunchinain-B1 antimicrobial peptide precursor
Daunchinain-B1 antimicrobial peptide precursor is an antibacterial peptide isolated from Babina daunchina. Synonyms: Thr-Ser-Lys-Lys-Pro-Leu-Leu-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Asn-Leu-Ser-Leu-Cys-Glu-Gln-Glu-Arg-Asn-Ala-Glu-Glu-Glu-Thr-Gly-Asp-Tyr-Pro-Asp-Gln-Arg-Asp-Val-Glu-Val-Glu-Lys-Arg.
Daunchinain-D1 antimicrobial peptide precursor
Daunchinain-D1 antimicrobial peptide precursor is an antibacterial peptide isolated from Babina daunchina. Synonyms: Thr-Met-Lys-Lys-Ser-Leu-Leu-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Asn-Leu-Ser-Leu-Cys-Glu-Gln-Glu-Gly-Asn-Ala-Glu-Glu-Glu-Thr-Gly-Asp-Asn-Pro-Asp-Gln-Arg-Glu-Asp-Glu-Val-Glu-Lys-Arg.
Daunomycin
Daunomycin is an intermediate of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-6,10,11-trihydroxy-1-methoxytetracene-5,12-dione; 8-Acetyl-5,12-dihydro-6,10,11-trihydroxy-1-methoxynaphthacene-5,12-dione; 5,12-Naphthacenedione, 8-acetyl-6,10,11-trihydroxy-1-methoxy-; Daunorubicin Impurity 5. Grade: ≥95%. CAS No. 20982-41-6. Molecular formula: C21H14O7. Mole weight: 378.33.
daunomycin-arachidonic acid complex
daunomycin-arachidonic acid complex. CAS No. 86589-37-9. Product ID: ACM86589379. Alfa Chemistry - ISO 9001:32057 Certified.
Daunomycinone
Daunomycinone is the aglycone core structure of the anthracycline antibiotics daunorubicin and doxorubicin, lacking their sugar moiety. As a key pharmacophore, it contributes to the DNA-intercalating and topoisomerase II inhibition properties of these drugs, enabling anticancer activity. While less potent than the glycosylated forms, daunomycinone retains cytotoxic effects by generating reactive oxygen species (ROS) and disrupting DNA replication. Synonyms: Daunorubicin Impurity A; (8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin EP Impurity A; (+)-Daunomycinone; NSC 109531; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; Daunomycin Aglicone; Daunomycinon; Daunorubicin Aglycone; Leukaemomycinone C; Daunorubicinone; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-; Epirubicin EP Impurity B. Grade: ≥95%. CAS No. 21794-55-8. Molecular formula: C21H18O8. Mole weight: 398.37.
Daunomycinone
Daunomycinone. Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione; (+)-Daunomycinone; Daunomycin aglicone; Daunorubicinone. Grades: Highly Purified. CAS No. 21794-55-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C21H18O8. US Biological Life Sciences.
Worldwide
Daunomycinone
Daunomycinone (NSC-109351) is a metabolite of Daunomycin (HY-13062A) and anticancer intermediate. Daunomycinone binds to nucleic acids synergistically with metal ions. Daunomycinone can be used in the research of leukemia[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC-109351. CAS No. 21794-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114658.
Daunomycinone-d3
The main metabolite of labeled Daunorubicin (DNR). Group: Biochemicals. Alternative Names: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione-d3; (+)-Daunomycinone-d3; Daunomycin Aglicone-d3; Daunomycinon-d3; Daunorubicin Aglycone-d3; Daunorubicinone-d3; Leukaemomycinone C-d3; NSC 109351-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Daunorubicin
Daunorubicin (Daunomycin) is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin inhibits DNA and RNA synthesis. Daunorubicin is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin is also an anthracycline antibiotic. Daunorubicin can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor[1][2][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Daunomycin; RP 13057; Rubidomycin. CAS No. 20830-81-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13062A.
Daunorubicin
Daunomycin is an anthracycline antibiotic produced by Streptomyces peucetius. The mechanism of action is the same as that of doxorubicin, which is inserted into DNA and inhibits RNA and DNA synthesis. It is mainly used for the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. It has anti-gram-positive bacteria, negative bacteria and tumor activity. Uses: Adcs cytotoxin. Synonyms: Doxorubicin EP Impurity A; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunomycin; Acetyladriamycin; Leukaemomycin C; Cerubidine; Rubidomycin; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl-3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; NSC 82151; (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione; Epirubicin EP Impurity D; Rubomycin C. Grade: 95%. CAS No. 20830-81-3. Molecular formula: C27H29NO10. Mole weight: 527.52.
Daunorubicin-[13C,d3]
Daunorubicin-[13C,d3], is the labelled analogue of Daunorubicin. Daunorubicin is used for acute myeloid leukemia, acute lymphocytic leukemia, chronic myelogenous leukemia, and Kaposi's sarcoma. Synonyms: Daunorubicin-13C,d3; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-3C,d3. Grade: 85% (CP); 98% atom D; 98% atom 13C. Molecular formula: C26[13C]H26D3NO10. Mole weight: 531.53.
Daunorubicin-13C,d3
Daunorubicin-13C,d3. Group: Biochemicals. Alternative Names: (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-13C,d3. Grades: Purified. CAS No. 20830-81-3 unlabeled. Pack Sizes: 250ug. Molecular Formula: C2613CH26D3NO10, Molecular Weight: 531.53. US Biological Life Sciences.
Worldwide
Daunorubicin 4'-O-α-D-Glucoside
Daunorubicin 4'-O-α-D-Glucoside is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-β-D-glucopyranuronosyl-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-β-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-α-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. CAS No. 229314-80-1. Molecular formula: C33H37NO16. Mole weight: 703.64.
Daunorubicin 4'-O-α-D-Glucoside Sodium Salt
Daunorubicin 4'-O-α-D-glucoside is a derivative of Daunorubicin. Daunorubicin is an anticancer drug that is often used in conjunction with other cytotoxic agents to treat various types of leukemias and carcinomas. Daunorubicin also provides a positive outlook for patients with acute promyelocytic leukemia, inducing remission in about half of the patients. Synonyms: (2S,3S,4S,5R,6S)-6-(((2S,3S,4S,6R)-6-(((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-4-amino-2-methyltetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate sodium salt; (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-4-O-α-D-glucopyranuronosyl-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Monosodium Salt. CAS No. 229314-76-5. Molecular formula: C33H36NNaO16. Mole weight: 725.63.
Daunorubicin Bromoketal Hydrobromide
Daunorubicin Bromoketal Hydrobromide is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 14-Bromo Dimethyl Ketal Daunorubicin Hydrobromide; 14-Bromo, 13-Deoxo, 13,13-Dimethoxy Daunorubicin Hydrobromide; Doxorubicin EP Impurity B HBr; (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrobromide (1:1); (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrobromide; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrobromide, (8S-cis)-. Grade: 85%. CAS No. 148218-14-8. Molecular formula: C29H35Br2NO11. Mole weight: 733.40.
Daunorubicin bromoketal hydrochloride
Daunorubicin bromoketal hydrochloride is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Daunorubicin bromo dimethyl ketal, hydrochloride; 14-Bromo Dimethyl Ketal Daunorubicin Hydrobromide; Doxorubicin EP Impurity B HCl; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-; (1S,3S)-3-(2-Bromo-1,1-dimethoxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: ≥95%. CAS No. 64291-57-2. Molecular formula: C29H34BrNO11.HCl. Mole weight: 688.94.
Daunorubicin Citrate
Daunorubicin Citrate is the citrate salt of daunorubicin, a naturally occurring anthracycline antibiotic isolated from Streptomyces peucetius. It possesses antineoplastic properties and is structurally characterized by a tetracyclic aglycone (daunomycinone) glycosidically linked to the aminosugar daunosamine. Applications: Indicated for the treatment of acute myeloid leukemia (aml), acute lymphoblastic leukemia (all), and other hematologic malignancies. daunorubicin citrate is an anthracycline antibiotic that intercalates dna and inhibits topoisomerase ii, triggering apoptotic cell death in rapidly dividing cells. it is also used in hiv-related kaposi sarcoma therapy. Category: Active pharmaceutical ingredients. Synonyms: Daunorubicin citrate liposome. CAS No. 371770-68-2. Product ID: API371770682. Molecular formula: C33H37NO17. Mole weight: 719.6. InChIKey: VNTHYLVDGVBPOU-QQYBVWGSSA-N.
Daunorubicin-[d3]
Daunorubicin-[d3], a meticulously stable isotope-enriched rendition of Daunorubicin, is an esteemed anthracycline antibiotic extensively employed in the research of diverse cancer modalities, encompassing acute myeloid leukemia, lymphomas and solid tumors. Synonyms: Daunorubicin-d3. Molecular formula: C27H26D3NO10. Mole weight: 530.54.
Daunorubicin EP Impurity B (Mixture of Diastereomers)
Daunorubicin EP Impurity B (Mixture of Diastereomers). Uses: For analytical and research use. Alternative Names: 28008-55-1 ((S)-Isomer); 28008-53-9 ((S)-Isomer, HCl salt); (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. Molecular formula: C27H31NO10. Mole weight: 529.54. Catalog: APB02226.
Daunorubicin EP Impurity E (Mixture of Diastereomers)
Daunorubicin EP Impurity E (Mixture of Diastereomers). Uses: For analytical and research use. Alternative Names: (8S,10S)-6,8,10,11-tetrahydroxy-8-((R)-1-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. Molecular formula: C21H20O8. Mole weight: 400.38. Catalog: APB05535.
Daunorubicin EP Impurity F
Daunorubicin EP Impurity F. Uses: For analytical and research use. Category: Impurity standards. Alternative Names: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-8-propionyl-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 771423-67-7. Molecular formula: C28H31NO10. Mole weight: 541.55. Catalog: APB771423677.
Daunorubicin hydrochloride
Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor[1][2][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride. CAS No. 23541-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13062.
Daunorubicin hydrochloride
25mg Pack Size. Group: Antibiotics, Research Organics & Inorganics. Formula: C27H29NO10 · HCl. CAS No. 23541-50-6. Prepack ID 11269897-25mg. Molecular Weight 563.98. See USA prepack pricing.
Daunorubicin hydrochloride
10mg Pack Size. Group: Antibiotics, Research Organics & Inorganics. Formula: C27H29NO10 · HCl. CAS No. 23541-50-6. Prepack ID 11269897-10mg. Molecular Weight 563.98. See USA prepack pricing.
Daunorubicin hydrochloride
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Uses: Adcs cytotoxin. Synonyms: RP 13057 Hydrochloride; Daunomycin; RP13057 Hydrochloride; RP-13057 Hydrochloride; Rubidomycin hydrochloride. Grade: >98%. CAS No. 23541-50-6. Molecular formula: C27H30ClNO10. Mole weight: 563.98.
Daunorubicin Hydrochloride (Daunomycin)
Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM in a cell-free assay. Daunorubicin is a topoisomerase II inhibitor that induces apoptosis.Daunorubicin (RP 13057) HCl can be used to induce animal models of Kidney Disease. Group: Inhibitors. Alternative Names: Rubidomycin HCl, RP 13057 HCl. CAS No. 23541-50-6. Pack Sizes: 10mg. Product ID: S3035. Formula: C27H29NO10. HCl. Smiles: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O.Cl. Storage Conditions: 2 years -80 in solvent.