A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Dasatinib Impurity HC1016-by-product f. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-N-(5-chloro-2-methylphenyl)thiazole-5-carboxamide. Molecular Formula: C11H10ClN3OS. Mole Weight: 267.73. Catalog: APB04933.
Dasatinib Impurity HC1017-by-product g
Dasatinib Impurity HC1017-by-product g. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-amino-N-(3-chloro-2-methylphenyl)thiazole-5-carboxamide. Molecular Formula: C11H10ClN3OS. Mole Weight: 267.73. Catalog: APB04931.
Dasatinib Impurity HC1020-by-product h
Dasatinib Impurity HC1020-by-product h. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(tert-butoxy)-6-chloro-2-methylpyrimidine. Molecular Formula: C9H13ClN2O. Mole Weight: 200.67. Catalog: APB04927.
Dasatinib Impurity HC1021-by-product i
Dasatinib Impurity HC1021-by-product i. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-di-tert-butoxy-2-methylpyrimidine. Molecular Formula: C13H22N2O2. Mole Weight: 238.33. Catalog: APB04929.
Dasatinib Impurity HC1022-by-product j
Dasatinib Impurity HC1022-by-product j. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,6-dichloro-2-(chloromethyl)pyrimidine. Molecular Formula: C5H3Cl3N2. Mole Weight: 197.45. Catalog: APB04926.
Dasatinib monohydrate
Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib monohydrate also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 monohydrate. CAS No. 863127-77-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10181B.
Dasatinib Monohydrate
Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Uses: Antineoplastic agents. Synonyms: BMS-354825 Monohydrate; BMS 354825 Monohydrate; BMS354825 Monohydrate; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate. Grades: >98%. CAS No. 863127-77-9. Molecular formula: C22H28ClN7O3S. Mole weight: 506.02.
Dasatinib Monohydrate
Dasatinib Monohydrate is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. It is a COVID19-related research product. Group: Biochemicals. Alternative Names: N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, monohydrate (9CI); BMS 35482503;Dasatinib hydrate. Grades: Highly Purified. CAS No. 863127-77-9. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClN?O?S (H?O), Molecular Weight: 506.02. US Biological Life Sciences.
Worldwide
Dasatinib N-oxide
Dasatinib N-oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src/Bcr-Abl inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 910297-52-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-133794.
Dasatinib N-Oxide
An oxidative metabolite of Dasatinib (M5 metabolite). Group: Biochemicals. Alternative Names: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide. Grades: Highly Purified. CAS No. 910297-52-8. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Dasatinib N-Oxide
Dasatinib N-Oxide is an oxidative metabolite of Dasatinib (M5 metabolite). Synonyms: N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide N-Oxide. Grades: > 95%. CAS No. 910297-52-8. Molecular formula: C22H26ClN7O3S. Mole weight: 504.
Dasiglucagon acetate
Dasiglucagon acetate is a glucagon analog for diabetic hypoglycemic treatment, which has a higher absorption rate and longer plasma elimination half-life than conventional reconstituted glucagon. Synonyms: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Aib-Ala-Arg-Ala-Glu-Glu-Phe-Val-Lys-Trp-Leu-Glu-Ser-Thr-OH.CH3CO2H; L-histidyl-L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-alpha-methyl-alanyl-L-alanyl-L-arginyl-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-phenylalanyl-L-valyl-L-lysyl-L-tryptophyl-L-leucyl-L-alpha-glutamyl-L-seryl-L-threonine acetic acid. Grades: ≥95%. Molecular formula: C154H226N38O52. Mole weight: 3441.67.
D-Asn(5)-AVP
D-Asn(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Asn-Vasopressin; D-Asn-AVP; H-Cys-Tyr-Phe-Gln-D-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Vasopressin, 5-D-asparagine-8-L-arginine-; 5-D-asparagine-Argipressin. CAS No. 2075715-46-5. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Asn 5-Oxytocin
D-Asn 5-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); H-Cys-Tyr-Ile-Gln-D-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, 5-D-asparagine-; [5-D-Asparagine]oxytocin; [D-Asn5]-Oxytocin; L-cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-D-asparagyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide (1->6)-disulfide. Grades: ≥95%. CAS No. 5754-53-0. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19.
Dasotraline
Dasotraline hydrochloride is a metabolite of sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50= 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-trans-Norsertraline; Norsertraline, (1R,4S)-trans-; (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine. CAS No. 675126-05-3. Molecular formula: C16H15Cl2N. Mole weight: 292.203.
Dasotraline hydrochloride
Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine , norepinephrine , and serotonin transporters with IC 50 values of 4, 6, and 11 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SEP-225289 hydrochloride. CAS No. 675126-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12850A.
Dasotraline hydrochloride
Dasotraline hydrochloride, also called as SEP-225289 hydrochloride, is a metabolite of Sertraline and a novel inhibitor of dopamine and norepinephrine reuptake that blocks dopamine, norepinephrine, andserotonin transporters (IC50 = 4, 6, and 11 nM, respectively). Synonyms: (1R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride; SEP-225,289; SEP225,289; SEP225,289; SEP-225289; SEP225289; SEP225289;; Dasotraline; Dasotraline HCl; Dasotraline hydrochloride. CAS No. 675126-08-6. Molecular formula: C16H16Cl3N. Mole weight: 328.66.
D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a K i value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme [1]. Uses: Scientific research. Group: Natural products. Alternative Names: H-D-Asn-OH. CAS No. 2058-58-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W010378.
D-Asparagine
D-Asparagine is an isomer of L-Asparagine (A790005) and is used by bacteria (such as Saccharomyces cerevisiae) as a sole nitrogen source for replication. L-Asparagine is also a competitive inhibitor of staphylococcal L-asparaginase and is used as a reagent to synthesize peptide antibiotics. Group: Biochemicals. Grades: Highly Purified. CAS No. 2058-58-4. Pack Sizes: 10g, 25g. Molecular Formula: C4H8N2O3, Molecular Weight: 132.12. US Biological Life Sciences.
Worldwide
D-Asparagine anhydrous
25g Pack Size. Group: Amino Acids, Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Peptide Reagents. Formula: C4H8N2O3. CAS No. 2058-58-4. Prepack ID 47565622-25g. Molecular Weight 132.12. See USA prepack pricing.
Synonyms: Moxifloxacin Impurity 52. Grades: >95% by HPLC. CAS No. 41928-40-9. Molecular formula: C4H10N2O2. Mole weight: 118.13.
D-Aspartamide
Cas No. 114818-26-7. Molecular formula: C4H9N3O2. Mole weight: 131.1.
D-aspartate ligase
This enzyme forms part of the peptidoglycan assembly pathway of Gram-positive bacteria grown in medium containing D-Asp. Normally, the side chains the acylate the 6-amino group of the L-lysine residue contain L-Ala-L-Ala but these amino acids are replaced by D-Asp when D-Asp is included in the medium. Hybrid chains containing L-Ala-D-Asp, L-Ala-L-Ala-D-Asp or D-Asp-L-Ala are not formed. The enzyme belongs in the ATP-grasp protein superfamily. The enzyme is highly specific for D-aspartate, as L-aspartate, D-glutamate, D-alanine, D-iso-asparagine and D-malic acid are not substrates. In Enterococcus faecium, the substrate D-aspartate is produced by EC 5.1.1.13, aspartate racemase. Group: Enzymes. Synonyms: Aslfm; UDP-MurNAc-pentapeptide:D-aspartate ligase; D-aspartic acid-activating enzyme. Enzyme Commission Number: EC 6.3.1.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5715; D-aspartate ligase; EC 6.3.1.12; Aslfm; UDP-MurNAc-pentapeptide:D-aspartate ligase; D-aspartic acid-activating enzyme. Cat No: EXWM-5715.
D-aspartate oxidase
A flavoprotein (FAD). Group: Enzymes. Synonyms: aspartic oxidase; D-aspartic oxidase. Enzyme Commission Number: EC 1.4.3.1. CAS No. 9029-20-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1465; D-aspartate oxidase; EC 1.4.3.1; 9029-20-3; aspartic oxidase; D-aspartic oxidase. Cat No: EXWM-1465.
D-Aspartic acid
25g Pack Size. Group: Amino Acids. Formula: C4H7NO4. CAS No. 1783-96-6. Prepack ID 12844702-25g. Molecular Weight 133.1. See USA prepack pricing.
D-Aspartic acid
D-Aspartic acid. CAS No. 1783-96-6. Molecular formula: C4H7NO4.
D-Aspartic acid
D-Aspartic acid is a kind of non-essential amino acid found in food sources and dietary supplements. It is an endogenous NMDA receptor agonist and has similar activity to the L-isomer. It is also a non-metabolizable substrate for EAA uptake systems. It adjusts melatonin synthesis in the pineal gland. It may be used as a therapeutic agent in the treatment of schizophrenia-related symptoms. Synonyms: (-)-Aspartic Acid; (R)-Aspartic Acid; D-(-)-Aspartic Acid; 2-Aminobutanedioic Acid; NSC 97922; NSC97922; NSC-97922; (R)-(-)-Aminosuccinic acid; (R)-2-Aminosuccinic acid; D-Aminosuccinic acid. Grades: 97%. CAS No. 1783-96-6. Molecular formula: C4H7NO4. Mole weight: 133.10.
D Aspartic Acid
D Aspartic Acid. Categories: d-aspartic acid; 1783-96-6.
CA, FL & NJ
D-Aspartic Acid
A non-essential amino acid found in food sources and dietary supplements. Its conjugate base D-aspartate has potential use as a a therapeutic agent in the treatment of schizophrenia-related symptoms. Group: Biochemicals. Grades: Highly Purified. CAS No. 1783-96-6. Pack Sizes: 5g, 25g, 50g, 100g, 250g. Molecular Formula: C?H?NO?, Molecular Weight: 133.1. US Biological Life Sciences.
Worldwide
D-Aspartic acid 99+%
D-Aspartic acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
D-Aspartic acid a-amide hydrochloride98+%
D-Aspartic acid a-amide hydrochloride98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 200260-37-3(net). Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
D-Aspartic acid a-benzyl ester98+%
D-Aspartic acid a-benzyl ester98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
D-Aspartic acid a-methyl ester is a protected form of D-Aspartic acid. D-Aspartic acid is the unnatural isomer of L-Aspartic acid. D-Aspartic acid naturally occurs in human ovarian follicular fluid, and is thought to be linked to oocyte quality. It is also found in the white matter of human brains, more specifically in myelin proteins. Synonyms: D-Asp-OMe; h-d-asp-ome; D-Asp-OMe; D-Aspartic acid,1-methyl ester; D-Aspartic acid alpha-methyl ester; (3R)-3-amino-4-methoxy-4-oxobutanoic acid; D Asp Ome. Grades: ≥ 98% (HPLC). CAS No. 65414-78-0. Molecular formula: C5H9NO4. Mole weight: 147.13.
D-Aspartic acid a-methyl ester
D-Aspartic acid a-methyl ester. Group: Biochemicals. Alternative Names: D-Asp-OMe. Grades: Highly Purified. CAS No. 65414-78-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
D-Aspartic acid sodium salt. Group: Biochemicals. Alternative Names: Sodium D-aspartate. Grades: Highly Purified. CAS No. 10329-81-4. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C4H6NO4·Na. US Biological Life Sciences.
Worldwide
DAT-230
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230-treatment in HT-1080 cells resulted in microtubule de-polymerization and G2/M phase arrest preceding apoptosis. Phosphor-cdc2 (thr14/tyr15) reduction, cyclin B1 accumulation and aberrant spindles denoted the cyclin B1-cdc2 complex active and M phase arrest in HT-1080 cells treated with DAT-230. Apoptosis induced by DAT-230 was related with the activation of caspase-9, caspase-3 and PARP cleavage, which were at the downstream of mitochondria. The decrease ratio of Bcl-2/Bax, elevation of NO and disruption of ΔΨm confirmed the causal relationship between DAT-230 and mitochondrial pathway. In vivo, DAT-230 delayed tumor growth, induced tumor perfusion decrease and extensive hemorrhagic-necrosis. Synonyms: DAT 230; DAT230. Grades: 98%. CAS No. 1504583-00-9. Molecular formula: C22H20BrN3O2S. Mole weight: 339.45.
Datelliptium chloride
Datelliptium chloride, derived from ellipticine, is a DNA-intercalating agent with good activity in murine tumor models over a broad range of doses. Synonyms: 2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol;chloride; 2-(diethylamino-2-ethyl)-9-hydroxyellipticinium; 2-DEHE; datelliptium chloride; detalliptinium; detalliptinium acetate salt; detalliptinium chloride; detalliptium acetate; diethylaminoethyl-2-OH-9-ellipticinium; NSC 311152; NSC 626718X; NSC-311152; SR 95156A; SR 95156B; SR-95156A. CAS No. 105118-14-7. Molecular formula: C23H28ClN3O. Mole weight: 397.94.
Datelliptium chloride
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 105118-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00337.
DATEM-E472e
Diacetyl tartaric acid esters of mono- and diglycerides of fatty acids, or simply DATEM, is an emulsifier used in breadmaking to strengthen the dough structure so that it can successfully expand during proofing and baking. Synonyms: DATEM---E472e;Diacetyl tartaric acid monodiglyceride;Acetylated single (double) glycerol fatty acid ester. CAS No. 977051-29-8. Product ID: CDF4-0258. Category: It is used in bread, buns and many other yeast-leavened bakery products at levels of 0.2-0.6% (based on flour weight). DATEM possesses excellent dough strengthening properties due to its ability to adsorb at the gas/liquid interface of dough and stabilize the foam structure trapped by the gluten matrix and prevent gas bubble coalescence.1,2 So, DATEM enhances gas (CO3) retention and improves tolerance to shocks in case of mechanical abuse during final proofing and baking. Due to its anionic nature, DATEM also has the capacity to interact with gluten proteins, promoting protein aggregation. Product Keywords: Food Emulsifiers; CDF4-0258; DATEM-E472e; 977051-29-8; DATEM---E472e;Diacetyl tartaric acid monodiglyceride;Acetylated single (double) glycerol fatty acid ester. Chemical Name: Diacety Tartaric Acid Esters of Mono & Diglycerides. Grade: Food grade. Stability and Storage Conditions: Prevent from moisture and caking. Sealed and stored in the low temperature, dry, cool and well-ventilated place. Forbid storing and transporting with