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| Product | Description | |
|---|---|---|
| DBCO-PEG2-Maleimide | DBCO-PEG2-Maleimide. Alternative Names: DBCO-NHCO-PEG2-maleimide; 2698339-31-8; DBCO-PEG2-Maleimide; DBCO-NH-PEG2-Mal; DBCO-NH-PEG2-Maleimide; SCHEMBL25457724; AKOS040743173; BP-25727. CAS No. 2698339-31-8. Molecular formula: C32H34N4O7. Mole weight: 586.7. |  |
| DBCO-PEG2-Val-Cit-PAB-MMAE | DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism. Uses: Scientific research. Category: Signaling pathways. CAS No. 2845934-59-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172287. |  |
| DBCO-(PEG2-VC-PAB-MMAE)2 | DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate[1]. DBCO-(PEG2-VC-PAB-MMAE)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-55-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126690. | |
| DBCO-PEG3-acid | DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-59-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-42974. | |
| DBCO-PEG3-GGFG-Exatecan | DBCO-PEG3-GGFG-Exatecan is a Drug-linker conjugate for ADC. DBCO-PEG3-GGFG-Exatecan contains the ADC linker (DBCO-PEG3-GGFG) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-71-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-177546. | |
| DBCO-PEG3-oxyamine | DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-oxyamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748394-67-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133429. | |
| DBCO-PEG3-TCO | DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755573-20-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-133428. | |
| DBCO-PEG3-VC-Exatecan | DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-70-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164792. | |
| DBCO-(PEG)3-VC-PAB-MMAE | DBCO-(PEG)3-VC-PAB-MMAE is a agent-linker conjugate for ADC. DBCO-(PEG)3-VC-PAB-MMAE is made by Monomethyl auristatin E (HY-15162) conjugats to DBCO-(PEG)3-vc-PAB linker. DBCO-(PEG)3-VC-PAB-MMAE can be used for the research of cancer[1]. DBCO-(PEG)3-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-60-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111012. | |
| DBCO-PEG4-alcohol | DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416711-60-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-140279. | |
| DBCO-PEG4-amine | DBCO-PEG4-amine. Alternative Names: DBCO-PEG4-amine TFA salt;DBCO-NHCOPEG4-amine. Grades: >98.0%. CAS No. 1840886-10-3. Molecular formula: C29H37N3O6. Mole weight: 523.62. | |
| DBCO-PEG4-Biotin | DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction[1]. DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255942-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130809. | |
| DBCO-PEG4-DBCO | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-130346. | |
| DBCO-PEG4-Desthiobiotin | DBCO-PEG4-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-PEG4-Desthiobiotin can be used in the synthesis of a series of PROTACs. Alternative Names: DBCO-PEG4-Desthiobiotin; 2032788-37-5; AKOS040743203; BP-22451; HY-140301; CS-0114730; N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide. CAS No. 2032788-37-5. Molecular formula: C39H53N5O8. Mole weight: 719.87. | |
| DBCO-PEG4-Eosin 5-isothiocyanate | DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DBCO-PEG4-Eosin Y. CAS No. 3065946-69-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-159529. | |
| DBCO-PEG4-GGFG-DX8951 | DBCO-PEG4-GGFG-DX8951 is a drug-linker conjugate for ADC by using DX8951 (Synonyms: Exatecan, a DNA topoisomerase I inhibitor), linked via DBCO-PEG4-GGFG. Alternative Names: DBCO-PEG4-GGFG-Exatecan. Molecular formula: C72H79FN10O17. Mole weight: 1375.48. | |
| DBCO-PEG4-GGFG-Dxd | DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2694856-51-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134723. | |
| DBCO-PEG4-Maleimide | DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120770. | |
| DBCO-PEG4-MMAF | DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2360411-65-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-133492. | |
| DBCO-PEG4-NHS ester | DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1427004-19-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140272. | |
| DBCO-PEG4-NHS ester | DBCO-PEG4-NHS ester is PEG derivative used as a cross-linker to react with primary amines. Alternative Names: Azadibenzocyclooctyne-PEG4-NHS ester. Grades: >95%. CAS No. 1427004-19-0. Molecular formula: C34H39N3O10. Mole weight: 649.69. | |
| DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Grades: >98.0%. CAS No. 2244602-23-9. Molecular formula: C88H126N12O20. Mole weight: 1672.01. | |
| DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244602-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130990. | |
| DBCO-PEG4-Val-Cit-PAB-PNP | DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. Alternative Names: 4-((17S,20S)-1-(DBCO-Butanedicarboxylamino)-17-isopropyl-15,18-dioxo-20-(3-ureidopropyl)-3,6,9,12-tetraoxa-16,19-diazahenicosan-21-amido)benzyl (4-nitrophenyl) carbonate. CAS No. 2226472-28-0. Molecular formula: C55H66N8O15. Mole weight: 1079.16. | |
| DBCO-PEG4-VA-PBD | DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241644-09-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133433. | |
| DBCO-PEG4-VC-PAB-DMEA-PNU-159682 | DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-56-2. Pack Sizes: 1 mg. Product ID: HY-126691. | |
| DBCO-PEG4-vc-PAB-Duocarmycin SA | DBCO-PEG4-vc-PAB-Duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB. Molecular formula: C79H95ClN12O20. Mole weight: 1568.14. | |
| DBCO-PEG4-vc-PAB-Duocarmycin TM | DBCO-PEG4-vc-PAB-Duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB. Molecular formula: C79H94ClN11O18. Mole weight: 1521.13. | |
| DBCO-Peg4-VC-PAB-MMAE | DBCO-Peg4-VC-PAB-MMAE is a cytotoxin and linker conjugate widely used in ADCs. Alternative Names: DBCO-PEG4-VC-PAB-MMAE; DBCO-PEG4-Val-Cit-PAB-MMAE. CAS No. 2129164-91-4. Molecular formula: C88H128N12O19. Mole weight: 1658.03. | |
| DBCO-PEG4-VC-PAB-MMAE | DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2129164-91-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136314. | |
| DBCO-PEG4-vc-PAB-MMAF | DBCO-PEG4-vc-PAB-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF, a potent tubulin polymerization inhibitor), linked via DBCO-PEG4-vc-PAB. Molecular formula: C88H126N12O20. Mole weight: 1672.04. | |
| DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM | DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via DBCO-PEG4-vc-PAB-(PEG2). Molecular formula: C83H103ClN12O18. Mole weight: 1592.25. | |
| DBCO-PEG5-NHS ester | DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2144395-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126885. | |
| DBCO-PEG6-NHS ester | DBCO-PEG6-NHS ester. Molecular formula: C38H47N3O12. Mole weight: 737.8. | |
| DBCO-PEG8-NHS ester | DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2553412-88-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-140273. | |
| DBCO-PEG8-VA-PAB-SG3199 | DBCO-PEG8-VA-PAB-SG3199 is a drug-linker conjugate for ADC by using SG3199 (a PBD dimer,has a potently cytotoxic against cancer cell lines), linked via DBCO-PEG8-VA-PAB. Molecular formula: C87H109N9O22. Mole weight: 1632.87. | |
| DBCO-PEG-Silane, MW 5K | DBCO-PEG-Silane, MW 5,000 is a Click Chemistry polyPEG reagent. The silane group enables coupling for surface modification. This reagent can be applied to situations when copper is a concern for DBCO-activated PEGylation. | |
| DBCO-Serinol Phosphoramidite | DBCO-Serinol Phosphoramidite is a quintessential reagent for biomedical research, a chemical compound that is omnipresent in the lab benches of esteemed molecular biologists. This versatile oligonucleotide synthesizer is engineered to conjugate with various biomolecules for a plethora of drug delivery and bioimaging applications. Alternative Names: 3-Dimethoxytrityloxy-2-(6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-capramido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C54H61N4O7P. Mole weight: 909.08. | |
| DBCO-S-S-PEG3-biotin | DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-S-S-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1430408-09-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140128. | |
| DBCO-sulfo-NHS Ester | DBCO-sulfo-NHS Ester. Alternative Names: 6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-caproic acid sulfo-N-hydroxysuccinimide ester, sodium salt; DBCO-Sulfo-NHS ester (sodium). Grades: >98.0%. CAS No. 1400191-52-7. Molecular formula: C25H21N2NaO8S. Mole weight: 532.50. | |
| DBCO-Sulfo-NHS ester sodium | DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1400191-52-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-123687. | |
| DBCO-Tetraacetyl mannosamine | DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3099388-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W588717. | |
| DBCO-Val-Cit-PABC-PNP | DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2994332-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130937. | |
| DBCO-Val-Cit-PAB-MMAE | DBCO-Val-Cit-PAB-MMAE is a drug-linker conjugate, which can be used for the synthesis of ADC molecules. MMAE (HY-15162) is a tubulin inhibitor, which can be used as an ADC toxin. DBCO-Val-Cit-PAB is the linker with the electrophilic group[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2768446-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W591408. | |
| DBD-COCl | DBD-COCl. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)benzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole. CAS No. 156153-43-4. Molecular formula: C11H13ClN4O4S. Mole weight: 332.76. Purity: >93.0%(T). Catalog: APB156153434. |  |
| DBD-CO-Hz | DBD-CO-Hz. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-(N-hydrazinocarbonylmethyl-N-methyl)aminobenzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-(N-hydrazinocarbonylmethyl-N-methyl)amino-2,1,3-benzoxadiazole. CAS No. 179951-63-4. Molecular formula: C11H16N6O4S. Mole weight: 328.35. Purity: >98.0%(HPLC). Catalog: APB179951634. | |
| DBD-NCS | DBD-NCS. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanatobenzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole. CAS No. 147611-81-2. Molecular formula: C9H8N4O3S2. Mole weight: 284.31. Catalog: APB147611812. | |
| D-benzoylarginine-4-nitroanilide amidase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. Group: Enzymes. Synonyms: benzoyl-D-arginine arylamidase; D-BAPA-ase. Enzyme Commission Number: EC 3.5.1.72. CAS No. 119345-26-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4463; D-benzoylarginine-4-nitroanilide amidase; EC 3.5.1.72; 119345-26-5; benzoyl-D-arginine arylamidase; D-BAPA-ase. Cat No: EXWM-4463. |  |
| D-Benzyl oxycarbonyl aspartic Anhydride | D-Benzyl oxycarbonyl aspartic Anhydride. Group: Biochemicals. Alternative Names: (R) -N- (Benzyloxycarbonyl) aspartic Anhydride; N-[(3R)-Tetrahydro-2,5-dioxo-3-furanyl]carbamic Acid Phenylmethyl Ester;N-[(3R)-Tetrahydro-2,5-dioxo-3-furanyl]carbamic Acid Benzyl Ester. Grades: Highly Purified. CAS No. 75443-52-8. Pack Sizes: 250mg. US Biological Life Sciences. |  Worldwide |
| DBeQ | DBeQ. Group: Biochemicals. Grades: Purified. CAS No. 177355-84-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| DBeQ | DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor, with an IC50 value of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits Vps4 with an IC50 of 11.5 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JRF 12. CAS No. 177355-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15945. | |
| DBeQ | DBeQ inhibits p97 competitively with respect to ATP, with Ki of 3.2 μM, suggesting that it binds to the active site of the D2 domain. Alternative Names: DBeQ; DBEQ; JRF12; JRF-12; JRF 12. Grades: >98%. CAS No. 177355-84-9. Molecular formula: C22H20N4. Mole weight: 340.42. | |
| dBET1 | dBET1 is a potent BRD4 protein degrader composed of a BET bromodomain inhibitor (+)-JQ1 and a sedative drug thalidomide. The (+)-JQ1 portion binds to the BET bromodomains, and the thalidomide binds to cereblon to form a cereblon E3 ubiquitin ligase complex, inducing cereblon-dependent BET protein degradation. Alternative Names: (6S)-4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. Grades: 98%. CAS No. 1799711-21-9. Molecular formula: C38H37ClN8O7S. Mole weight: 785.27. | |
| dBET1 | dBET1 is a PROTAC connected by ligands for Cereblon and BRD4 with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 (HY-13030) linked to NSC 527179 (HY-14658) with a linker[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799711-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101838. | |
| dBET57 | dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4CRBN E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2. Alternative Names: dBET 57; dBET-57; 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-2,3,9-trimethyl-, (6S)-; 2-[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(2-{[2-(2,6-dioxo-3-piperidinyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethyl)acetamide. Grades: ≥95%. CAS No. 1883863-52-2. Molecular formula: C34H31ClN8O5S. Mole weight: 699.18. | |
| dBET57 | dBET57 is an effective and selective BRD4BD1 degrader based on PROTAC technology, with the ability to induce cell apoptosis and anti-tumor activity. dBET57 mediates the recruitment of the E3 ubiquitin ligase CRL4Cereblon, showing a DC50/5h value of 500 nM for BRD4BD1[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883863-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123844. | |
| dBET6 | Novel degrader of BET bromodomain proteins, prompting a collapse of global elongation that phenocopies CDK9 inhibition. dBET6 is a highly potent, selective and cell-permeable degrader of BET based on PROTAC, with an IC50 of 14 nM, and has antitumor activity. Alternative Names: 2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)-acetamide. CAS No. 1950634-92-0. Molecular formula: C42H45ClN8O7S. Mole weight: 841.37. | |
| dBET6 | dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1950634-92-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112588. | |
| dBET6 | dBET6 is a highly cell-permeable PROTAC degrader of BET bromodomains with an IC50 of 14 nM for BRD4 binding. dBET6 also induces c-MYC downregulation and apoptosis. Group: Inhibitors. CAS No. 1950634-92-0. Pack Sizes: 5mg. Product ID: S8762. Formula: C42H45ClN8O7S. Smiles: CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCCCCCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)C7=CC=C(C=C7)Cl)C. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| D-β-Asp15-Retatrutide | D-β-Asp15-Retatrutide. | |
| D-β-Asp9-Retatrutide | D-β-Asp9-Retatrutide. | |
| D-β-Homoalanine hydrochloride | D-β-Homoalanine hydrochloride, an amino acid derivative, is of significant interest owing to its multiple applications ranging from peptide synthesis to the development of natural product antibiotics. Research has also been conducted to unveil its potential antiviral and antitumor properties, representing an area of pharmacological significance with far-reaching implications. Alternative Names: H-D-Ala-(C#CH2)OH HCl; H-D-β-homoAla-OH HCl; (R)-3-Aminobutanoic acid hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 58610-42-7. Molecular formula: C4H10ClNO2. Mole weight: 139.58. | |
| D-beta-Homoallylglycine hydrochloride | D-beta-Homoallylglycine hydrochloride. Group: Biochemicals. Alternative Names: D-b-HomoGly(allyl)-OH·HCl; (R)-3-Amino-5-hexenoic acid hydrochloride. Grades: Highly Purified. CAS No. 82448-92-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| D-beta-homoglutamic acid HCl | D-beta-homoglutamic acid HCl. Alternative Names: D-β-HomoGlu-OH HCl; (R)-3-Amino-hexanedioic acid hydrochloride; H-D-β-HomoGlu-OH HCl; D-HomoGlu-OH HCl. CAS No. 63492-85-3. Molecular formula: C6H12ClNO4. Mole weight: 197.62. | |
| D-β-homoleucine HCl | D-β-homoleucine HCl. Alternative Names: (R)-3-Amino-5-methylhexanoic acid hydrochloride; D b homoleucine HCl. CAS No. 1276055-44-7. Molecular formula: C7H16ClNO2. Mole weight: 181.66. | |
| D-beta-homomethionine | D-beta-homomethionine. Alternative Names: L-β-Homomethionine; L-β-HomoMet-OH. Grades: ≥ 98% by NMR. CAS No. 75946-25-7. Molecular formula: C6H13NO2S. Mole weight: 163.24. | |
| D-β-Homophenylalanine hydrochloride | D-β-Homophenylalanine hydrochloride. Alternative Names: H-D-Phe-(C#CH2)OH HCl; H-D-β-homoPhe-OH HCl; (R)-3-Amino-4-phenylbutanoic acid hydrochloride. Grades: ≥ 95% (NMR). CAS No. 145149-50-4. Molecular formula: C10H14ClNO2. Mole weight: 215.68. | |
| D-beta-Homophenylalanine hydrochloride | D-beta-Homophenylalanine hydrochloride. Group: Biochemicals. Alternative Names: D-b-HomoPhe-OH·HCl; (R)-3-Amino-4-phenylbutyric acid hydrochloride. Grades: Highly Purified. CAS No. 145149-50-4. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| D-β-Homophenylglycine hydrochloride | D-β-Homophenylglycine hydrochloride. Alternative Names: H-D-Phg-(C#CH2)OH HCl; H-D-β-Phe-OH HCl; (S)-3-Amino-3-phenylpropanoic acid hydrochloride. Grades: 95%. CAS No. 83649-47-2. Molecular formula: C9H12ClNO2. Mole weight: 201.65. | |
| D-β-Homoproline hydrochloride | D-β-Homoproline hydrochloride is the hydrochloride salf from of D-β-Homoproline, a starting material for GABA inhibitors. Alternative Names: H-D-Pro-(C#CH2)OH HCl; H-D-β-homoPro-OH HCl; (R)-Pyrrolidine-2-acetic acid hydrochloride. Grades: ≥ 98%. CAS No. 439918-59-9. Molecular formula: C6H12ClNO2. Mole weight: 165.62. | |
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