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| Product | Description | |
|---|---|---|
| DB1976 dihydrochloride | DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. It potently inhibits PU.1 binding and strongly inhibits the PU.1/DNA complex in vitro. DB1976 has apoptosis-inducing effect. Synonyms: DB1976 dihydrochloride; DB1976 (dihydrochloride); 2369663-93-2; DB1976 hydrochloride; DB1976 (hydrochloride); AKOS040732928; HY-135797A; CS-0114127; 2-[5-(6-carbamimidoyl-1H-benzimidazol-2-yl)selenophen-2-yl]-3H-benzimidazole-5-carboximidamide; dihydrochloride. Grade: ≥98%. CAS No. 2369663-93-2. Molecular formula: C20H18Cl2N8Se. Mole weight: 520.28. |  |
| DB1976 dihydrochloride | DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2369663-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135797A. |  |
| DB-2073 | DB-2073 is produced by the strain of Pseudomonas B-9004. It has the activity against streptococcus pneumoniae and tinea gypsum mold. Synonyms: 2-n-hexyl-5-n-propylresorcinol; Antibiotic DB 2073; 2-Hexyl-5-propyl-1,3-benzenediol; BRN 1964593. CAS No. 39341-78-1. Molecular formula: C15H24O2. Mole weight: 236.35. | |
| DB2115 tertahydrochloride | DB2115 tertahydrochloride is a potent inhibitor of myeloid master regulator PU.1. CAS No. 1366126-19-3. Molecular formula: C32H34Cl4N8O2. Mole weight: 704.48. | |
| DB2115 tertahydrochloride | DB2115 tetrahydrochloride is a highly selective PU.1 inhibitor that suppresses the binding of PU.1 to DNA (IC50: 2.3 nM). DB2115 tetrahydrochloride can inhibit tumor cell proliferation and induce apoptosis. DB2115 tetrahydrochloride can be used in the research of tumors such as leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1366126-19-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124676A. | |
| DB2313 | DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170606-74-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124629. | |
| DB2313 | DB2313 is a potent inhibitor of the essential transcriptional factor PU.1 with IC50 value of 14 nM. Synonyms: 2,2'-((((2-Fluoro-1,3-phenylene)bis(methylene))bis(oxy))bis(4,1-phenylene))bis(N-isopropyl-1H-benzo[d]imidazole-6-carboximidamide). CAS No. 2170606-74-1. Molecular formula: C42H41FN8O2. Mole weight: 708.8. | |
| DB2313 HCl | DB2313 is a potent inhibitor of the essential transcriptional factor PU.1 with IC50 value of 14 nM. Synonyms: DB2313 hydrochloride; DB 2313 hydrochloride; DB-2313 hydrochloride; DB2313 tetrahydrochloride; DB 2313 HCl; DB-2313 HCl. CAS No. 2170606-75-2. Molecular formula: C42H45Cl4FN8O2. Mole weight: 854.7. | |
| DB-3-291 | DB-3-291 is potent and selective PROTAC CSK degrader, with a Kd of 1 nM (Pink: CSK ligand (HY-131669); Blue: E3 ligase ligand (HY-103597); Black: linker (HY-N2407))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769753-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137345. | |
| DB772 | DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1451058-50-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114621. | |
| DB818 | DB818 is a synthetic HOXA9 inhibitor that downregulates the expression of HOXA9 transcriptional target genes. Synonyms: DB 818; DB-818. Grade: >98%. CAS No. 790241-43-9. Molecular formula: C19H16N6S. Mole weight: 360.44. | |
| DB-cAMP-AM | DB-cAMP-AM is a precursor of DB-cAMP. The dibutyryl cAMP is released after the metabolism of DB-cAMP-AM by esterases. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 159910-48-2. Molecular formula: C21H28N5O10P. Mole weight: 541.5. | |
| DB-cCMP | DB-cCMP is a membrane-permeant prodrug of cCMP, the potential further second messenger. Synonyms: N4, 2'- O- Dibutyrylcytidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 97 % by HPLC. CAS No. 64649-87-2. Molecular formula: C17H23N3O9P · Na. Mole weight: 467.3. | |
| DB-cGMP | DB-cGMP, an exceedingly compelling analogue of cyclic guanosine monophosphate (cGMP), a pivotal secondary messenger in myriad biological processes, serves as an invaluable tool in biomedical research. With a primary focus on unraveling the intricate role of cGMP in signal transduction pathways, cellular proliferation, and apoptosis, it facilitates the understanding of diseases stemming from aberrant cGMP signaling. Synonyms: N2, 2'- O- Dibutyrylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 51116-00-8. Molecular formula: C18H23N5O9P · Na. Mole weight: 507.4. | |
| DBCO-acid | DBCO-acid. Uses: White to light yellow powder to crystal. Synonyms: 11,12-Didehydro-gamma-oxodibenz[b,f]azocine-5(6H)-butanoic acid. Grade: > 98.0 %. CAS No. 1353016-70-2. Molecular formula: C19H15NO3. Mole weight: 305.33. | |
| DBCO-acid | DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester ((HY-115524) and (HY-115545)), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353016-70-2. Pack Sizes: 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-42972. | |
| DBCO-amine | DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-amine is used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255942-06-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-W000423. | |
| DBCO-Amine Oxalate | A DBCO-containing reagent in the synthesis of high-generation polyester dendrimers. Synonyms: Azadibenzocyclooctyne-Amine Oxalate. Molecular formula: C18H16N2O.C2H2O4. Mole weight: 366.37. | |
| DBCO-β-Glu-PEG12-Exatecan | DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan can be used as a Drug-Linker Conjugate for ADC molecule[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3025107-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160788. | |
| DBCO-Biotin | DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1418217-95-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123916. | |
| DBCO-Biotin | An intermidate used for antibody-drug conjugates. Synonyms: Azadibenzocyclooctyne-Biotin conjugate; N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide. CAS No. 1418217-95-4. Molecular formula: C28H30N4O3S. Mole weight: 502.63. | |
| DBCO-?C6-?acid | DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1425485-72-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-121805. | |
| DBCO-CONH-PEG4-acid | DBCO-CONH-PEG4-acid. CAS No. 1537170-85-6. Purity: 95%+. Product ID: ACM1537170856. Molecular formula: C30H36N2O8. Mole weight: 552.62. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| DBCO-CONH-S-S-NHS ester | DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1435934-53-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133413. | |
| DBCO-Cy3 | DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DBCO-Sulfo-Cy3. CAS No. 1782950-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-D1069. | |
| DBCO-cyclo(RGDfK) | DBCO-cyclo(RGDfK) is a clickable RGD peptide and DBCO derivative of cyclo(RGDfK) (HY-P0023)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2425606-55-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11428. | |
| DBCO-dT CE Phosphoramidite | DBCO-dT CE Phosphoramidite is a copper-free click chemistry reagent designed for site-specific incorporation of dibenzocyclooctyne (DBCO) into oligonucleotides during solid-phase synthesis, enabling bioorthogonal conjugation with azide-functionalized molecules. The reagent features a DBCO moiety linked to a deoxythymidine (dT) base via a spacer arm, with a 3'-phosphoramidite group for efficient coupling in automated synthesizers. This phosphoramidite is ideal for preparing molecular probes, diagnostic assays, or therapeutic oligonucleotides requiring post-synthesis labeling. Synonyms: DBCO-dT Phosphoramidite. Grade: ≥95%. Molecular formula: C69H80N7O11P. Mole weight: 1214.41. | |
| DBCO Ir catayst | DBCO Ir catalyst is an iridium catalyst labeled with DBCO. DBCO Ir catalyst can be used for in situ labeling and imaging of biomolecules (e.g., proteins, nucleic acids) in living organisms or for constructing targeted drug delivery systems[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2695594-15-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160523. | |
| DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1395786-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-116270. | |
| DBCO-NHCO-PEG12-biotin | DBCO-NHCO-PEG12-biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG12-biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C55H83N5O16S. Mole weight: 1102.34. | |
| DBCO-NHCO-PEG13-NHS ester | DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2784618-59-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140276. | |
| DBCO-NHCO-PEG2-Biotin | DBCO-NHCO-PEG2-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG2-Biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C36H45N5O6S. Mole weight: 675.84. | |
| DBCO-NHCO-PEG4-amine | DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255942-08-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-124386. | |
| DBCO-NHCO-PEG6-Biotin | DBCO-NHCO-PEG6-Biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-NHCO-PEG6-Biotin can be used in the synthesis of a series of PROTACs. Molecular formula: C43H59N5O10S. Mole weight: 838.02. | |
| DBCO-NHCO-S-S-NHS ester | DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2749932-04-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-133412. | |
| DBCO-NH-PEG12-Biotin | DBCO-NH-PEG12-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG12-Biotin conjugate. Grade: >95%. Molecular formula: C55H83N5O16S. Mole weight: 1102.34. | |
| DBCO-NH-PEG2-Biotin | DBCO-NH-PEG2-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG2-Biotin conjugate. Grade: >95%. Molecular formula: C35H43N5O6S. Mole weight: 661.81. | |
| DBCO-NH-PEG4-biotin | DBCO-NH-PEG4-biotin is a heterobifunctional PEG linker containing a biotin group and an alkyne group. The alkyne group can react with azide in various biomolecules via click chemistry. The PEG spacer increases membrane impermeability of molecules conjugated to biotin. Synonyms: Dibenzocyclooctyne-PEG4-Biotin conjugate; DBCO-PEG4-Biotin. Grade: >95%. CAS No. 1255942-07-4. Molecular formula: C39H51N5O8S. Mole weight: 749.92. | |
| DBCO-NH-PEG6-Biotin | DBCO-NH-PEG6-Biotin is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Azadibenzocyclooctyne-PEG6-Biotin conjugate. Grade: >95%. Molecular formula: C43H59N5O10S. Mole weight: 838.02. | |
| DBCO-NHS ester | DBCO-NHS ester. Synonyms: DBCO-NHS; N-Succinimidyl 4-[(5-Aza-3,4:7,8-dibenzocyclooct-1-yne)-5-yl]-4-oxobutyrate. Grade: > 99.0 %. CAS No. 1353016-71-3. Molecular formula: C23H18N2O5. Mole weight: 402.40. | |
| DBCO-NHS ester | DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353016-71-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-42973. | |
| DBCO-NHS ester 2 | DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1384870-47-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-115524. | |
| DBCO-PEG12-Maleimide | DBCO-PEG12-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG12-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2962826-52-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133374. | |
| DBCO-PEG12-NHS ester | DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093934-94-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140274. | |
| DBCO-PEG1-NHS ester | DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2228857-34-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-140271. | |
| DBCO-PEG24-Maleimide | DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2924872-84-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W879048. | |
| DBCO-PEG24-NHS ester | DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2765066-38-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-151835. | |
| DBCO-PEG2-Val-Cit-PAB-MMAE | DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism. Uses: Scientific research. Category: Signaling pathways. CAS No. 2845934-59-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172287. | |
| DBCO-(PEG2-VC-PAB-MMAE)2 | DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody agent conjugate[1]. DBCO-(PEG2-VC-PAB-MMAE)2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-55-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126690. | |
| DBCO-PEG3-acid | DBCO-PEG3-acid is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG3-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-59-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-42974. | |
| DBCO-PEG3-Biotin | A biotinylation reagent containing a DBCO moiety for click chemistry. Grade: >95%. Molecular formula: C37H47N5O7S. Mole weight: 705.32. | |
| DBCO-PEG3-GGFG-Exatecan | DBCO-PEG3-GGFG-Exatecan is a Drug-linker conjugate for ADC. DBCO-PEG3-GGFG-Exatecan contains the ADC linker (DBCO-PEG3-GGFG) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-71-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-177546. | |
| DBCO-PEG3-oxyamine | DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-oxyamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748394-67-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133429. | |
| DBCO-PEG3-TCO | DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755573-20-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-133428. | |
| DBCO-PEG3-VC-Exatecan | DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-70-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164792. | |
| DBCO-(PEG)3-VC-PAB-MMAE | DBCO-(PEG)3-VC-PAB-MMAE is a agent-linker conjugate for ADC. DBCO-(PEG)3-VC-PAB-MMAE is made by Monomethyl auristatin E (HY-15162) conjugats to DBCO-(PEG)3-vc-PAB linker. DBCO-(PEG)3-VC-PAB-MMAE can be used for the research of cancer[1]. DBCO-(PEG)3-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2754384-60-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111012. | |
| DBCO-PEG4-alcohol | DBCO-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-alcohol is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416711-60-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-140279. | |
| DBCO-PEG4-Biotin | DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction[1]. DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255942-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130809. | |
| DBCO-PEG4-DBCO | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-130346. | |
| DBCO-PEG4-Desthiobiotin | DBCO-PEG4-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-PEG4-Desthiobiotin can be used in the synthesis of a series of PROTACs. Synonyms: DBCO-PEG4-Desthiobiotin; 2032788-37-5; AKOS040743203; BP-22451; HY-140301; CS-0114730; N-[2-[2-[2-[2-[3-[[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide. CAS No. 2032788-37-5. Molecular formula: C39H53N5O8. Mole weight: 719.87. | |
| DBCO-PEG4-Eosin 5-isothiocyanate | DBCO-PEG4-Eosin 5-isothiocyanate (DBCO-PEG4-Eosin Y) is a fluorescent probe. DBCO-PEG4-Eosin 5-isothiocyanate contains a clickable functional group, DBCO, and four PEG units. DBCO-PEG4-Eosin 5-isothiocyanate can be used for various imaging detections. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DBCO-PEG4-Eosin Y. CAS No. 3065946-69-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-159529. | |
| DBCO-PEG4-GGFG-Dxd | DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2694856-51-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134723. | |
| DBCO-PEG4-Maleimide | DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120770. | |
| DBCO-PEG4-MMAF | DBCO-PEG4-MMAF is a agent-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the linker DBCO-PEG4. DBCO-PEG4-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2360411-65-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-133492. | |
| DBCO-PEG4-NHS ester | DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1427004-19-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140272. | |
| DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF consists a cleavable 4 unit PEG ADC linker (DBCO-PEG4-Val-Cit-PAB) and a potent tubulin polymerization inhibitor (MMAF). DBCO-PEG4-Val-Cit-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG4-Val-Cit-PAB-MMAF is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2244602-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130990. | |
| DBCO-PEG4-VA-PBD | DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1]. DBCO-PEG4-VA-PBD is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241644-09-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133433. | |
| DBCO-PEG4-VC-PAB-DMEA-PNU-159682 | DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682. DBCO-PEG4-VC-PAB-DMEA-PNU-159682 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-56-2. Pack Sizes: 1 mg. Product ID: HY-126691. | |
| DBCO-PEG4-VC-PAB-MMAE | DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2129164-91-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136314. | |
| DBCO-PEG4-vc-PAB-MMAF | DBCO-PEG4-vc-PAB-MMAF is a drug-linker conjugate for ADC by using Monomethylauristatin F (MMAF, a potent tubulin polymerization inhibitor), linked via DBCO-PEG4-vc-PAB. Molecular formula: C88H126N12O20. Mole weight: 1672.04. | |
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