A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
DC-Y13-27 is a DC-Y13 derivative and YTHDF2 inhibitor (KD: 37.9 ?M). DC-Y13-27 inhibits YTHDF2, restores FOXO3 and TIMP1 protein levels, and reduces MMP1/3/7/9 expression. DC-Y13-27 induces Pyroptosis and increases IL-1? secretion. DC-Y13-27 reduces intervertebral disc degeneration and enhances the response to radiotherapy in colon cancer and melanoma. DC-Y13-27 has antitumor activity against breast cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154919.
D-Cyclopentylglycine 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
D-Cyclopropylglycine ≥95% (NMR)
D-Cyclopropylglycine ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
D-Cycloserine
It is produced by the strain of Streptomyces orchidaceus, Str. lavendulae, Str. roseochromogenes. It can inhibit bacterial alanine racase, D-alanyl-D-alanine synthetase, and interfere with cell wall biosynthesis. Its antibacterial spectrum is wide, and it has activity against gram-positive bacteria, negative bacteria, mycobacterium, rickettsia and amoeba of dysentery. It is now used as a second-line anti-tuberculosis drug. Uses: Anti-infective agents, urinary; antibiotics, antitubercular; antimetabolites. Synonyms: Oxamycin; Antibiotic PA-94; JN-21; Seromycin; orientomycin; Cyclo-D-serine; Cyclorin; D-4-amino-3-isoxazolidinone; Cicloserina; Farmiserina; Miroseryn; alpha-Cycloserine; (+)-4-Amino-3-isoxazolidinone; (+)-Cycloserine; (R)-(+)-Cycloserine; (R)-4-Amino-3-isoxazolidinone; (R)-Cycloserine. Grade: ≥ 97% by HPLC. CAS No. 68-41-7. Molecular formula: C3H6N2O2. Mole weight: 102.09.
D-Cycloserine
D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 68-41-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0030.
D-Cycloserine
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Chiral Compounds, Organics, Research Organics & Inorganics. Formula: C3H6N2O2. CAS No. 68-41-7. Prepack ID 90028981-1g. Molecular Weight 102.09. See USA prepack pricing.
D-Cycloserine
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C3H6N2O2. CAS No. 68-41-7. Prepack ID 69907662-5g. Molecular Weight 102.09. See USA prepack pricing.
D-Cycloserine
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C3H6N2O2. CAS No. 68-41-7. Prepack ID 69907662-1g. Molecular Weight 102.09. See USA prepack pricing.
D-Cycloserine
25g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C3H6N2O2. CAS No. 68-41-7. Prepack ID 69907662-25g. Molecular Weight 102.09. See USA prepack pricing.
D-Cycloserine dimer
D-Cycloserine dimer is an intermediate in the biosynthesis of S-adenosylmethionine, a cofactor for enzyme-catalyzed methylations. Synonyms: (3R,6R)-3,6-Bis[(aminooxy)methyl]-2,5-piperazinedione; D-3,6-Bis(aminooxymethyl)-2,5-diketopiperazine; D-3,6-Bis(aminoxymethyl)-2,5-dioxopiperazine. Grade: > 95%. CAS No. 16337-02-3. Molecular formula: C6H12N4O4. Mole weight: 204.18.
D-Cys(1)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(1)-Vasopressin; Vasopressin, 1-D-cysteine-8-L-arginine-; H-D-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 66513-07-3. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Cys(2)-Octreotide
D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-DCys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); [2-D-Cysteine]octreotide; DPhe-DCys-F-DTrp-KTC-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity G; D-Phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Cys(2)-Octreotide trifluoroacetate salt
D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol trifluoroacetate salt (Disulfide bridge: Cys2-Cys7); Octreotide EP Impurity G trifluoroacetate salt. Grade: 95%.
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S)-1-[(4R,7S,10S,13S,16S,19S)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grade: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
D-Cys(6)-AVP
D-Cys(6)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: D-Cys(6)-Vasopressin; Vasopressin, 6-D-cysteine-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asn-D-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-D-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 163659-75-4. Molecular formula: C46H65N15O12S2. Mole weight: 1084.24.
D-Cys7-Eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-DCys-NH2(Mpr1&Cys7 bridge); Mpr-Har-GDWP-DCys-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-Asp-Trp-Pro-D-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-D-cysteinamide (1->7)-disulfide; D-Cys7 Eptifibatide; 7-D-Cys Eptifibatide; [D-Cys]7-Eptifibatide; [D-Cys7]-Eptifibatide; D-Cys(7)-Eptifibatide; (D-Cys)7 Eptifibatide impurity. Grade: ≥95%. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
D-Cys(7)-Octreotide
D-Cys(7)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-DCys-Thr-ol(Cys2&Cys7 bridge); [7-D-cysteine]octreotide; Octreotide EP Impurity B; [D-Cys7]-Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-D-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-D-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DPhe-CF-DTrp-KT-DCys-Thr-ol(Cys2&Cys7 bridge). Grade: 98%. CAS No. 1211530-36-7. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
1g Pack Size. Group: Stains & Indicators. Formula: C3H7NO2S. CAS No. 921-01-7. Prepack ID 28831664-1g. Molecular Weight 121.16. See USA prepack pricing.
D-Cysteine
D-Cysteine is a strong inhibitor of Escherichia coli growth and also functions to provide inorganic sulfates for the sulfation of xenobiotics. D-Cysteine is a non-physiological isomer of L-Cysteine, and is not involved in protein or glutathione synthesis. Synonyms: (S)-Cysteine; (S)-2-amino-3-mercaptopropanoic acid; D-Zystein; D-Amino-3-mercaptopropionic acid; D-Cys; (2S)-2-amino-3-mercaptopropanoic acid. Grade: ≥97%. CAS No. 921-01-7. Molecular formula: C3H7NO2S. Mole weight: 121.16.
D-Cysteine
D-Cysteine. Group: Biochemicals. Alternative Names: (S)-2-Amino-3-mercaptopropionic acid. Grades: Highly Purified. CAS No. 921-01-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C3H7NO2S. US Biological Life Sciences.
Worldwide
D-Cysteine 99+%
D-Cysteine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
D-cysteine desulfhydrase
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. This enzyme participates in cysteine metabolism. Group: Enzymes. Synonyms: D-cysteine lyase; D-cysteine sulfide-lyase (deaminating). Enzyme Commission Number: EC 4.4.1.15. CAS No. 84012-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5317; D-cysteine desulfhydrase; EC 4.4.1.15; 84012-74-8; D-cysteine lyase; D-cysteine sulfide-lyase (deaminating). Cat No: EXWM-5317.
D-Cystine bis(methyl ester) dihydrochloride ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. CAS No. 144000-36-2. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
DCZ0415
DCZ0415, a potent TRIP13 inhibitor, impairs nonhomologous end joining repair and inhibits NF-?B activity. DCZ0415 induces anti-myeloma activity in vitro, in vivo, and in primary cells derived from drug-resistant myeloma patients[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242470-43-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130603.
DCZ0415
DCZ0415 is a TRIP13 inhibitor that impairs nonhomologous end joining repair and inhibits NF-κB activity. DCZ0415 clinically for the treatment of a subset of CRCs that exhibit dysregulated TRIP13 and FGFR4. Synonyms: 2-(4-(Pyridin-4-ylmethyl)phenyl)-4,4a,5,5a,6,6a-hexahydro-4,6-ethenocyclopropa[f]isoindole-1,3(2H,3aH)-dione. Grade: 99%. CAS No. 2242470-43-3. Molecular formula: C23H20N2O2. Mole weight: 356.42.
DCzDCN
DCzDCN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3',5'-Di(carbazol-9-yl)-[1,1'-biphenyl]-3,5-dicarbonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1352800-07-7. Molecular formula: C38H22N4. Mole weight: 534.61 g/mol. Product ID: ACM1352800077. Alfa Chemistry ISO 9001:2015 Certified.
DCzTrz
DCzTrz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9'-(5-(4,6-Diphenyl-1,3,5-triazin-2-yl)-1,3-phenylene)bis(9H-carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1106730-48-6. Molecular formula: C45H29N5. Mole weight: 639.75 g/mol. Product ID: ACM1106730486. Alfa Chemistry ISO 9001:2015 Certified.
DD1
DD1 is a proteasome inhibitor that targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. Synonyms: 3,3'-Diamino-4'-methoxyflavone; 4H-1-Benzopyran-4-one, 3-amino-2-(3-amino-4-methoxyphenyl)-. Grade: >98%. CAS No. 187585-11-1. Molecular formula: C16H14N2O3. Mole weight: 282.29.
DD1
DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 187585-11-1. Pack Sizes: 1 mg. Product ID: HY-120035.
D-(+)-Darunavir
D-(+)-Darunavir is a highly efficacious antiretroviral compound, demonstrating compelling utility in studying HIV-1 infection. By impeding the viral protease enzyme, its pharmacological action effectively averts the fragmentation of viral polyproteins, thereby decisively impeding viral replication. Synonyms: (+)-Darunavir; 1399859-60-9; D-(+)-Darunavir; Darunavir, (+)-; NCL9DHY4E3; UNII-NCL9DHY4E3; (3S,3aR,6aS)-Hexahydrofuro(2,3-b)furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate; [(3aR,4S,6aS)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2R,3S)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate; Carbamic acid, N-((1R,2S)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3S,3aR,6aS)-hexahydrofuro(2,3-b)furan-3-yl ester; (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl ((2R,3S)-4-((4-amino-N-isobutylphenyl)sulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate. Grade: > 95%. CAS No. 1399859-60-9. Molecular formula: C27H37N3O7S. Mole weight: 547.66.
ddATP-α-S
ddATP-α-S is used in mass spectrometric genotyping. Synonyms: 2', 3'- Dideoxyadenosine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154902-26-8. Molecular formula: C10H16N5O10P3S (free acid). Mole weight: 491.3 (free acid).
ddCTP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddCTP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dCTP in cells. Uses: Ddctp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: 2',3'-Dideoxycytidine-5'-Triphosphate; Zalcitabine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-. Grade: ≥95% by AX-HPLC. CAS No. 66004-77-1. Molecular formula: C9H16N3O12P3 (free acid). Mole weight: 451.16 (free acid).
ddCTP-α-S
ddCTP-α-S is used in mass spectrometry genotyping. Synonyms: 2', 3'- Dideoxycytidine- 5'- O- (1- thiotriphosphate), Rp-/Sp-isomers. Grade: ≥ 95% by HPLC for mixture of Rp-/Sp-isomers. CAS No. 154771-49-0. Molecular formula: C9H16N3O11P3S (free acid). Mole weight: 467.2 (free acid).
DDCzTrz
DDCzTrz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9',9'',9'''-((6-Phenyl-1,3,5-triazine-2,4-diyl)bis(benzene-5,3,1-triyl))tetrakis(9H -carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 1685282-47-6. Molecular formula: C69H43N7. Mole weight: 970.13 g/mol. Product ID: ACM1685282476. Alfa Chemistry ISO 9001:2015 Certified.
DDD107498
DDD107498 is a novel multiple-stage antimalarial agent that inhibits P. falciparum translation elongation factor 2. Synonyms: M-5717; DDD-498; DDD498; DDD-107498. CAS No. 1469439-69-7. Molecular formula: C27H31FN4O2. Mole weight: 462.56.
DDD107498 succinate
DDD107498 succinate is a potent and orally active antimalarial inhibitor. It inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Synonyms: DDD-498 succinate. Grade: 99%. CAS No. 2444781-71-7. Molecular formula: C31H37FN4O6. Mole weight: 580.65.
DDD-85365
DDD-85365 is an oral drug developed promisingly for the treatment of visceral leishmaniasis. Uses: The potential treatment of visceral leishmaniasis. Synonyms: DDD 85365; DDD85365.
DDD85646
DDD85646 is a moderately bioavailable pyrazole sulphonamide inhibitor of T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. Synonyms: IMP-366; 2,6-Dichloro-4-(2-Piperazin-1-Ylpyridin-4-Yl)-N-(1,3,5-Trimethyl-1h-Pyrazol-4-Yl)benzenesulfonamide. Grade: ≥98%. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.4.
DDD85646
DDD85646 is a T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. DDD85646 has potent activity against the enzyme (IC(50) = 2 nM) and T. brucei (EC(50) = 2 nM) in culture. DDD85646 has good oral pharmacokinetics and cures rodent models of peripheral HAT infection. DDD85646 provides an excellent tool for validation of T. brucei NMT as a drug target for HAT as well as a valuable lead for further optimization. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DDD85646; DDD-85646; DDD 85646. Product Category: Others. Appearance: Solid powder. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.42. Purity: >98%. IUPACName: 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide. Canonical SMILES: O=S(C1=C(Cl)C=C(C2=CC(N3CCNCC3)=NC=C2)C=C1Cl)(NC4=C(C)N(C)N=C4C)=O. Product ID: ACM1215010551. Alfa Chemistry ISO 9001:2015 Certified.
DDD85646
DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMP-366. CAS No. 1215010-55-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103056.
Dde Biotin-PEG4-alkyne is a polyethylene glycol (PEG)-based PROTAC linker. Dde Biotin-PEG4-alkyne can be used in the synthesis of a series of PROTACs. CAS No. 1802908-00-4. Molecular formula: C32H50N4O8S. Mole weight: 650.83.