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| Product | Description | |
|---|---|---|
| DBCO-PEG5-NHS ester | DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1][2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2144395-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126885. |  |
| DBCO-PEG8-NHS ester | DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2553412-88-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-140273. | |
| DBCO-Serinol Phosphoramidite | DBCO-Serinol Phosphoramidite is a quintessential reagent for biomedical research, a chemical compound that is omnipresent in the lab benches of esteemed molecular biologists. This versatile oligonucleotide synthesizer is engineered to conjugate with various biomolecules for a plethora of drug delivery and bioimaging applications. Synonyms: 3-Dimethoxytrityloxy-2-(6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-capramido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C54H61N4O7P. Mole weight: 909.08. |  |
| DBCO-S-S-PEG3-biotin | DBCO-S-S-PEG3-biotin is a polyethylene glycol (PEG)-based PROTAC linker. DBCO-S-S-PEG3-biotin can be used in the synthesis of a series of PROTACs. Synonyms: Azadibenzocyclooctyne-S-S-PEG3-biotin conjugate. Grade: >99%. CAS No. 1430408-09-5. Molecular formula: C42H56N6O8S3. Mole weight: 869.12. | |
| DBCO-S-S-PEG3-biotin | DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-S-S-PEG3-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1430408-09-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140128. | |
| DBCO-SS-PEG4-Biotin | DBCO-SS-PEG4-Biotin. Grade: ≥95%. Molecular formula: C45H62N6O9S3. Mole weight: 927.20. | |
| DBCO-Sulfo-Link-biotin | DBCO-Sulfo-Link-biotin. Synonyms: WS DBCO-Biotin; 1-((3-((Z)-dibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl)amino)-1-oxo-3-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)propane-2-sulfonic acid. Grade: >98.0%. CAS No. 1363444-70-5. Molecular formula: C31H35N5O7S2. Mole weight: 653.77. | |
| DBCO-sulfo-NHS Ester | DBCO-sulfo-NHS Ester. Synonyms: 6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-caproic acid sulfo-N-hydroxysuccinimide ester, sodium salt; DBCO-Sulfo-NHS ester (sodium). Grade: >98.0%. CAS No. 1400191-52-7. Molecular formula: C25H21N2NaO8S. Mole weight: 532.50. | |
| DBCO-Sulfo-NHS ester sodium | DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1400191-52-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-123687. | |
| DBCO-Tetraacetyl mannosamine | DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 3099388-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W588717. | |
| DBCO-Val-Cit-PABC-PNP | DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2994332-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130937. | |
| DBCO-Val-Cit-PAB-MMAE | DBCO-Val-Cit-PAB-MMAE is a drug-linker conjugate, which can be used for the synthesis of ADC molecules. MMAE (HY-15162) is a tubulin inhibitor, which can be used as an ADC toxin. DBCO-Val-Cit-PAB is the linker with the electrophilic group[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2768446-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W591408. | |
| DBD-COCl | DBD-COCl. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)benzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-(N-chloroformylmethyl-N-methylamino)-2,1,3-benzoxadiazole. CAS No. 156153-43-4. Molecular formula: C11H13ClN4O4S. Mole weight: 332.76. Purity: >93.0%(T). Catalog: APB156153434. |  |
| DBD-CO-Hz | DBD-CO-Hz. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-(N-hydrazinocarbonylmethyl-N-methyl)aminobenzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-(N-hydrazinocarbonylmethyl-N-methyl)amino-2,1,3-benzoxadiazole. CAS No. 179951-63-4. Molecular formula: C11H16N6O4S. Mole weight: 328.35. Purity: >98.0%(HPLC). Catalog: APB179951634. | |
| DBD-NCS | DBD-NCS. Uses: For analytical and research use. Alternative Names: 4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanatobenzofurazan; 4-(N,N-Dimethylaminosulfonyl)-7-isothiocyanato-2,1,3-benzoxadiazole. CAS No. 147611-81-2. Molecular formula: C9H8N4O3S2. Mole weight: 284.31. Catalog: APB147611812. | |
| D-benzoylarginine-4-nitroanilide amidase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. Group: Enzymes. Synonyms: benzoyl-D-arginine arylamidase; D-BAPA-ase. Enzyme Commission Number: EC 3.5.1.72. CAS No. 119345-26-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4463; D-benzoylarginine-4-nitroanilide amidase; EC 3.5.1.72; 119345-26-5; benzoyl-D-arginine arylamidase; D-BAPA-ase. Cat No: EXWM-4463. |  |
| D-Benzyl oxycarbonyl aspartic Anhydride | D-Benzyl oxycarbonyl aspartic Anhydride. Group: Biochemicals. Alternative Names: (R) -N- (Benzyloxycarbonyl) aspartic Anhydride; N-[(3R)-Tetrahydro-2,5-dioxo-3-furanyl]carbamic Acid Phenylmethyl Ester;N-[(3R)-Tetrahydro-2,5-dioxo-3-furanyl]carbamic Acid Benzyl Ester. Grades: Highly Purified. CAS No. 75443-52-8. Pack Sizes: 250mg. US Biological Life Sciences. |  Worldwide |
| DBeQ | DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor, with an IC50 value of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits Vps4 with an IC50 of 11.5 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JRF 12. CAS No. 177355-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15945. | |
| DBeQ | DBeQ inhibits p97 competitively with respect to ATP, with Ki of 3.2 μM, suggesting that it binds to the active site of the D2 domain. Synonyms: DBeQ; DBEQ; JRF12; JRF-12; JRF 12. Grade: >98%. CAS No. 177355-84-9. Molecular formula: C22H20N4. Mole weight: 340.42. | |
| DBeQ | DBeQ. Group: Biochemicals. Grades: Purified. CAS No. 177355-84-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| dBET1 | dBET1 is a PROTAC connected by ligands for Cereblon and BRD4 with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 (HY-13030) linked to NSC 527179 (HY-14658) with a linker[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799711-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101838. | |
| dBET57 | dBET57 is an effective and selective BRD4BD1 degrader based on PROTAC technology, with the ability to induce cell apoptosis and anti-tumor activity. dBET57 mediates the recruitment of the E3 ubiquitin ligase CRL4Cereblon, showing a DC50/5h value of 500 nM for BRD4BD1[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883863-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123844. | |
| dBET6 | dBET6 is a highly cell-permeable PROTAC degrader of BET bromodomains with an IC50 of 14 nM for BRD4 binding. dBET6 also induces c-MYC downregulation and apoptosis. Group: Inhibitors. CAS No. 1950634-92-0. Pack Sizes: 5mg. Product ID: S8762. Formula: C42H45ClN8O7S. Smiles: CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCCCCCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)C7=CC=C(C=C7)Cl)C. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| dBET6 | dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1950634-92-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112588. | |
| D-β-Homoalanine hydrochloride | D-β-Homoalanine hydrochloride, an amino acid derivative, is of significant interest owing to its multiple applications ranging from peptide synthesis to the development of natural product antibiotics. Research has also been conducted to unveil its potential antiviral and antitumor properties, representing an area of pharmacological significance with far-reaching implications. Synonyms: H-D-Ala-(C#CH2)OH HCl; H-D-β-homoAla-OH HCl; (R)-3-Aminobutanoic acid hydrochloride. Grade: ≥ 98% (HPLC). CAS No. 58610-42-7. Molecular formula: C4H10ClNO2. Mole weight: 139.58. | |
| D-beta-Homoallylglycine hydrochloride | D-beta-Homoallylglycine hydrochloride. Group: Biochemicals. Alternative Names: D-b-HomoGly(allyl)-OH·HCl; (R)-3-Amino-5-hexenoic acid hydrochloride. Grades: Highly Purified. CAS No. 82448-92-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| D-beta-homoglutamic acid HCl | D-beta-homoglutamic acid HCl. Synonyms: D-β-HomoGlu-OH HCl; (R)-3-Amino-hexanedioic acid hydrochloride; H-D-β-HomoGlu-OH HCl; D-HomoGlu-OH HCl. CAS No. 63492-85-3. Molecular formula: C6H12ClNO4. Mole weight: 197.62. | |
| D-β-homoleucine HCl | D-β-homoleucine HCl. Synonyms: (R)-3-Amino-5-methylhexanoic acid hydrochloride; D b homoleucine HCl. CAS No. 1276055-44-7. Molecular formula: C7H16ClNO2. Mole weight: 181.66. | |
| D-beta-homomethionine | D-beta-homomethionine. Synonyms: L-β-Homomethionine; L-β-HomoMet-OH. Grade: ≥ 98% by NMR. CAS No. 75946-25-7. Molecular formula: C6H13NO2S. Mole weight: 163.24. | |
| D-β-Homophenylalanine hydrochloride | D-β-Homophenylalanine hydrochloride. Synonyms: H-D-Phe-(C#CH2)OH HCl; H-D-β-homoPhe-OH HCl; (R)-3-Amino-4-phenylbutanoic acid hydrochloride. Grade: ≥ 95% (NMR). CAS No. 145149-50-4. Molecular formula: C10H14ClNO2. Mole weight: 215.68. | |
| D-beta-Homophenylalanine hydrochloride | D-beta-Homophenylalanine hydrochloride. Group: Biochemicals. Alternative Names: D-b-HomoPhe-OH·HCl; (R)-3-Amino-4-phenylbutyric acid hydrochloride. Grades: Highly Purified. CAS No. 145149-50-4. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences. | Worldwide |
| D-β-Homophenylglycine hydrochloride | D-β-Homophenylglycine hydrochloride. Synonyms: H-D-Phg-(C#CH2)OH HCl; H-D-β-Phe-OH HCl; (S)-3-Amino-3-phenylpropanoic acid hydrochloride. Grade: 95%. CAS No. 83649-47-2. Molecular formula: C9H12ClNO2. Mole weight: 201.65. | |
| D-β-Homoproline hydrochloride | D-β-Homoproline hydrochloride is the hydrochloride salf from of D-β-Homoproline, a starting material for GABA inhibitors. Synonyms: H-D-Pro-(C#CH2)OH HCl; H-D-β-homoPro-OH HCl; (R)-Pyrrolidine-2-acetic acid hydrochloride. Grade: ≥ 98%. CAS No. 439918-59-9. Molecular formula: C6H12ClNO2. Mole weight: 165.62. | |
| D-β-Homoserine | D-β-Homoserine. Synonyms: H-D-Ser-(C#CH2)OH; H-D-β-homoSer-OH; (S)-3-Amino-4-hydroxybutanoic acid. Grade: ≥ 98% (HPLC). CAS No. 16504-57-7. Molecular formula: C4H9NO3. Mole weight: 119.12. | |
| D-beta-Homoserine | D-beta-Homoserine. Group: Biochemicals. Alternative Names: D-b-HomoSer-OH; (S)-3-Amino-4-hydroxy-butyric acid. Grades: Highly Purified. CAS No. 16504-57-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| D-β-homotryptophan HCl | D-β-homotryptophan HCl. Synonyms: (R)-3-Amino-4-(1H-indol-3-yl)butanoic acid hydrochloride; L-beta-Homotryptophan hydrochloride; D-beta-homotryptophan HCl; D b homotryptophan HCl. CAS No. 477250-51-4. Molecular formula: C12H15ClN2O2. Mole weight: 254.71. | |
| D-β-indanylglycine | D-β-indanylglycine. Synonyms: D-2-Indanylgly-OH. Grade: ≥ 98%. CAS No. 181227-46-3. Molecular formula: C11H13NO2. Mole weight: 191.23. | |
| DBG-3D diacid | DBG-3D diacid is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: 4-(((5-((2-Carboxyethyl)(pyridin-2-yl)carbamoyl)-1-methyl-1H-benzo[d]imidazol-2-yl)methyl)amino)benzoic acid; Dabigatran Impurity 69. CAS No. 1253792-34-5. Molecular formula: C25H23N5O5. Mole weight: 473.49. | |
| D-b-Homophenylalanine hydrochloride ≥95% (NMR) | D-b-Homophenylalanine hydrochloride ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| D-b-Homopropargylglycine hydrochloride | D-b-Homopropargylglycine hydrochloride. Group: Biochemicals. Alternative Names: D-b-Homopropargylglycine hydrochloride; (R)-3-Amino-5-hexynoic acid hydrochloride. Grades: Highly Purified. CAS No. 332064-87-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H9NO2·HCl. US Biological Life Sciences. | Worldwide |
| D-b-Homopropargylglycine hydrochloride 98+% (HPLC) | D-b-Homopropargylglycine hydrochloride 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| DBIBB | DBIBB is a non-lipid agonist of LPA2 (EC50 = 0.10 μM) that is a G protein-coupled receptor which plays roles in protecting against radiation-induced cell death and it has no effect at other LPA receptor subtypes. Synonyms: 2-[[[4-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)butyl]amino]sulfonyl]-benzoic acid. Grade: ≥98%. CAS No. 1569309-92-7. Molecular formula: C23H20N2O6S. Mole weight: 452.5. | |
| DBIBB | DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1569309-92-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117779. | |
| D-Biopterin | D-Biopterin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| D-(+)-Biotin | 5g Pack Size. Group: Analytical Reagents, Biochemicals. Formula: C10H16N2O3S. CAS No. 58-85-5. Prepack ID 20337504-5g. Molecular Weight 244.31. See USA prepack pricing. |  |
| D-(+)-Biotin | 1g Pack Size. Group: Analytical Reagents, Biochemicals. Formula: C10H16N2O3S. CAS No. 58-85-5. Prepack ID 20337504-1g. Molecular Weight 244.31. See USA prepack pricing. | |
| D-(+)-Biotin | D-(+)-Biotin is an important ubiquitous metabolism coenzyme. Category: Active pharmaceutical ingredients. CAS No. 58-85-5. Product ID: API58855. Molecular formula: C10H16N2O3S. Mole weight: 244.3. Appearance: Powder. |  |
| D-(+)-Biotin | D-(+)-Biotin is a coenzyme that offers three possible binding sites. Applications: An important ubiquitous metabolism coenzyme. Group: Coenzymes. Synonyms: Vitamin H; 5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid; Biotin. CAS No. 58-85-5. Purity: ≥99%. Mole weight: 244.3. Appearance: Powder. Form: Solid. Vitamin H; 5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid; Biotin; D-(+)-Biotin; 58-85-5. Cat No: COEC-007. | |
| D-Biotin 1% Trit | D-Biotin 1% Trit. |  CA, FL & NJ |
| D-(+)BIOTIN 2-NITROPHENYL ESTER | D-(+)BIOTIN 2-NITROPHENYL ESTER. Synonyms: D-(+)BIOTIN 2-NITROPHENYL ESTER. Grade: 95%. CAS No. 131303-71-4. Molecular formula: C16H19N3O5S. Mole weight: 365.4. | |
| D-Biotin dimer acid | D-Biotin dimer acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1163708-46-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C18H28N4O4S2. US Biological Life Sciences. | Worldwide |
| D-Biotin p-nitrophenyl ester | D-Biotin p-nitrophenyl ester, can be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. Synonyms: PBNP; 4-NITROPHENYL (+)-BIOTINATE; (+)-BIOTIN 4-NITROPHENYL ESTER; BIOTIN P-NITROPHENYL ESTER; BIOTIN-ONP; BNP; Biotin-ONP; (+)-Biotin 4-nitrophenyl ester; d-Biotin p-nitrophenyl ester; Biotinyl-4-nitrophenyl ester; (+)-Biotin-ONP; Biotin-p-nitrophenyl ester. Grade: 95%. CAS No. 33755-53-2. Molecular formula: C16H19N3O5S. Mole weight: 365.40. | |
| D Biotin USP | D Biotin USP. | CA, FL & NJ |
| D-Bis-pantothenyl-b-aminoethyl disulfide | D-Bis-pantothenyl-b-aminoethyl disulfide. Alternative Names: D-Pantethine. CAS No. 16816-67-4. Purity: 95+%. Product ID: ACM16816674-2. Molecular formula: C22H42N4O8S2. Mole weight: 554.72. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| DBM 1285 dihydrochloride | DBM 1285 dihydrochloride is a p38 MAPK inhibitor supressing p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo. It was shown to attenuate zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Synonyms: DBM 1285 dihydrochloride; DBM1285 dihydrochloride; DBM-1285 dihydrochloride; N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride. Grade: ≥98% by HPLC. CAS No. 1782532-29-9. Molecular formula: C21H22FN5S.2HCl. Mole weight: 468.42. | |
| DBM 1285 dihydrochloride | DBM 1285 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| DBM-C5-VC-PAB-MMAE | DBM-C5-VC-PAB-MMAE (Compound 3a) is a Drug-Linker conjugate for ADC. DBM-C5-VC-PAB-MMAE is composed of a linker C5-VC-PAB with a maleimide group DBM and an ADC toxin MMAE (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1644228-55-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164088. | |
| DBM-GGFG-NH-O-CO-Exatecan | DBM-GGFG-NH-O-CO-Exatecan (Example 4, Compound 14) is a conjugate of an ADC drug toxin molecule and a linker. DBM-GGFG-NH-O-CO-Exatecan is a complete antibody-drug conjugate intermediate that integrates a potent camptothecin-based toxin, a cleavable peptide linker (GGFG), and a reactive terminus that can directly conjugate to antibodies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769152-95-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160807. | |
| DBM-MMAF | DBM-MMAF is a agent-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody agent conjugate (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1810001-93-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136287. | |
| DBP | DBP. Alternative Names: 5,10,15,20-Tetraphenylbisbenz[5,6]indeno[1,2,3-cd:1',2',3'-lm]peryleRed 2. CAS No. 175606-05-0. Molecular formula: C64H36. Mole weight: 804.97. IUPAC Name: 7,14,25,32-tetraphenylundecacyclo[21.13.2.22,5.03,19.04,16.06,15.08,13.020,37.024,33.026,31.034,38]tetraconta-1,3,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39-icosaene. SMILES: c1ccc(cc1)-c2c-3c(-c4ccc5c6ccc7-c8c(-c9ccc(c%10ccc-3c4c5%10)c6c79)c(-c%11ccccc%11)c%12ccccc%12c8-c%13ccccc%13)c(-c%14ccccc%14)c%15ccccc2%15. InChI: InChI=1S/C64H36/c1-5-17-37(18-6-1)53-41-25-13-14-26-42(41)54(38-19-7-2-8-20-38)62-50-34-30-46-48-32-36-52-60-51(35-31-47(58(48)60)45-29-33-49(61(53)62)59(50)57(45)46)63-55(39-21-9-3-10-22-39)43-27-15-16-28-44(43)56(64(52)63)40-23-11-4-12-24-40/h1-36H. |  |
| DBPR108 | DBPR108 is an IC50=15 nM DPP IV inhibitor displays a more than 3000-fold selectivity over DPP8 DPP9, FAP and DPP-II. TThe in vivo effects of DBPR108, including inhibition of plasma DPP-IV activity and suppression of blood glucose elevation, were also demonstrated. DBPR108 is a potent, selective, long-acting and safe DPP-IV inhibitor as a potential treatment of type 2 diabetes mellitus. Synonyms: DBPR-108; DBPR 108; DBPR108. Grade: >98%. CAS No. 1186426-66-3. Molecular formula: C16H25FN4O2. Mole weight: 324.39. | |
| DBPR112 | DBPR112 is an orally active EGFR inhibitor based on furanopyrimidine, with IC50s of 15 nM and 48 nM for EGFRWT and L858R/T790M, respectively. DBPR112 can occupy the ATP-binding site and has significant antitumor effects. Synonyms: 2-Butenamide, 4-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]-, (2E)-; (S,E)-4-(dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)but-2-enamide; (2E)-4-(Dimethylamino)-N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]-2-butenamide. Grade: ≥98%. CAS No. 1226549-49-0. Molecular formula: C32H31N5O3. Mole weight: 533.62. | |
| dBRD9 | dBRD9,a PROTAC, can selective degrades BRD9. dBRD9 improves the bromine domain binding profile and reduces the binding activity of the whole BET family[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170679-45-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-117690. | |
| dBRD 9-A | dBRD 9-A is a selective BRD9 PROTAC degrader. dBRD 9-A induces near complete BRD9 degradation dependent on E3 ubiquitin ligase CRBN and BRD9 bromodomain engagement, and drives loss of BRD9 chromatin binding genome-wide. dBRD 9-A downregulates oncogenic SS18-SSX-driven transcriptional programs, super enhancer-associated gene expression, and SS18-SSX1 super enhancer binding, and depletes GBAF complex members GLTSCR1/1L from SS18-SSX complexes. dBRD 9-A induces cell cycle arrest and increases apoptosis in synovial sarcoma cells. dBRD 9-A can be used for the research of synovial sarcoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170679-42-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148739. | |
| DBU | DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1,8-Diazabicyclo[5.4.0]undec-7-ene. CAS No. 6674-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 500 g. Product ID: HY-20556. | |
| DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene) | DBU (1,8-Diazabicyclo[5.4.0]undec-7-ene). CAS No. 6674-22-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| D-Buthionine | D-Buthionine is an analog of Buthionine sulfoximine, which is a γ-glutamylcysteine synthetase inhibitor used to increase the sensitivity of parasites to oxidative antiparasitic drugs. Uses: (r)-homocysteine thioether. Synonyms: S-Butyl-D-homocysteine; D-2-Amino-4-(butylthio)butyric Acid; n-Butyl-D-homocysteine; D-Homocysteine, S-butyl-; (R)-2-Amino-4-(butylthio)butanoic acid. Grade: 95%. CAS No. 13073-22-8. Molecular formula: C8H17NO2S. Mole weight: 191.29. | |
| D-Buthionine | D-Buthionine. Group: Biochemicals. Alternative Names: S-Butyl-D-homocysteine; D-2-Amino-4-(butylthio)butyric acid; n-Butyl-D-homocysteine. Grades: Highly Purified. CAS No. 13073-22-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H17NO2S. US Biological Life Sciences. | Worldwide |
| D-Buthionine-(S,R)-sulfoximine | D-Buthionine-(S,R)-sulfoximine is an analog of Buthionine sulfoximine, which is a γ-glutamylcysteine synthetase inhibitor used to increase the sensitivity of parasites to oxidative antiparasitic drugs. Uses: A potent and specific inhibitor of alpha-glutamylcysteine synthetase. Synonyms: (2R)-2-Amino-4-(S-butylsulfonimidoyl)butanoic Acid; (R)-Buthionine sulfoximine; (R)-2-amino-4-(S-butylsulfonimidoyl)butyric acid; Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-, (2R)-; (R)-2-amino-4-((S,R)-butylsulfonimidoyl)butanoic acid. Grade: ≥90%. CAS No. 113158-69-3. Molecular formula: C8H18N2O3S. Mole weight: 222.30. | |
| D-Buthionine-(S,R)-sulfoximine | D-Buthionine-(S,R)-sulfoximine. Group: Biochemicals. Alternative Names: (2S) -2-Amino-4- (S-butylsulfonimidoyl) butanoic acid; D-Buthionine sulfoximine. Grades: Highly Purified. CAS No. 113158-69-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H18N2O3S. US Biological Life Sciences. | Worldwide |
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