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Emtricitabine Impurity 7. Uses: For analytical and research use. Alternative Names: (2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid. CAS No. 1238210-10-0. Molecular formula: C8H8FN3O4S. Mole weight: 261.23. Catalog: APB1238210100.
Emtricitabine Impurity 8
Emtricitabine Impurity 8. Uses: For analytical and research use. Alternative Names: 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one. CAS No. 152128-77-3. Molecular formula: C8H10FN3O4S. Mole weight: 263.25. Catalog: APB152128773.
Emtricitabine Impurity 9
Emtricitabine Impurity 9. Uses: For analytical and research use. Alternative Names: 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 145986-11-4. Molecular formula: C8H9FN2O4S. Mole weight: 248.23. Catalog: APB145986114.
Emtricitabine Impurity CFTU1
Emtricitabine Impurity CFTU1. Uses: For analytical and research use. Alternative Names: (3R,6S,11S,11aR)-11-fluorotetrahydro-2H-3,6-epoxypyrimido[6,1-b][1,6,3]oxathiazocine-8,10(3H,9H)-dione. Molecular formula: C8H9FN2O4S. Mole weight: 248.23. Catalog: APB05546.
Emtricitabine Impurity CFTU2
Emtricitabine Impurity CFTU2. Uses: For analytical and research use. Alternative Names: (3R,6S,11R,11aR)-11-fluorotetrahydro-2H-3,6-epoxypyrimido[6,1-b][1,6,3]oxathiazocine-8,10(3H,9H)-dione. Molecular formula: C8H9FN2O4S. Mole weight: 248.23. Catalog: APB05680.
Emtricitabine Impurity G
Emtricitabine Impurity G. Uses: For analytical and research use. Alternative Names: 4-amino-5-fluoro-1-((2R,3S,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one. CAS No. 1160303-44-5. Molecular formula: C8H10FN3O4S. Mole weight: 263.25. Catalog: APB1160303445.
Emtricitabine Impurity RRO
Emtricitabine Impurity RRO. Uses: For analytical and research use. Alternative Names: 4-amino-1-(2-((1,2-dihydroxyethyl)thio)-1-hydroxyethyl)-5-fluoropyrimidin-2(1H)-one. Molecular formula: C8H12FN3O4S. Mole weight: 265.26. Catalog: APB05677.
Emtricitabine Isopropyl Carbamate
Emtricitabine Isopropyl Carbamate is a derivative of Emtricitabine.Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: Isopropyl (5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate. Grade: > 95%. Molecular formula: C12H16FN3O5S. Mole weight: 333.34.
Emtricitabine Menthyl Ester
Emtricitabine Menthyl Ester is an impurity of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: [1R-[1α(2S*,5R*),2β,5α]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid 5-Methyl-2-(1-methylethyl)cyclohexyl Ester. CAS No. 147126-75-8. Molecular formula: C18H26FN3O4S. Mole weight: 399.48.
Emtricitabine Monophosphate Triethylammonium Salt
A metabolite of (-)-Emtricitabine. Grade: 96%. Molecular formula: C8H11FN3O6PS xC6H15N. Mole weight: 327.23.
Emtricitabine N,N'-Methylene Dimer
Emtricitabine N,N'-Methylene Dimer is a derivative compound of Emtricitabine, a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine. Synonyms: Emtricitabine Tenofovir FT4 IMP; Emtricitabine Symmetric Dimer; 4,4'-(Methylenediimino)bis[5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone]. Grade: 97%. CAS No. 1962114-97-1. Molecular formula: C17H20F2N6O6S2. Mole weight: 506.50.
Emtricitabine N,N'-Methylene t-Butyldimethylsilyl Dimer is an intermediate in synthesizing Emtricitabine N,N'-Methylene Dimer, a derivative compound of Emtricitabine, a reverse transcriptase inhibitor. It is effective antiviral agent against HIV, and other viruses replicating in a similiar manner. A nucleoside analog structurally related to Lamivudine. Synonyms: 4,4'-(Methylenediimino)bis{1-[(2R,5S)-2-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-1,3-oxathiolan-5-yl]-5-fluoro-2(1H)-pyrimidinone}; (R,S)-4,4'-(Methylenebis(azanediyl))bis(1-((2R,5S)-2-(((tert-butyldimethylsilyl)oxy)methyl)-1,3-oxathiolan-5-yl)-5-fluoropyrimidin-2(1H)-one). Molecular formula: C29H48F2N6O6S2Si2. Mole weight: 735.02.
Emtricitabine O-β-D-Glucuronide Sodium Salt
Emtricitabine O-β-D-Glucuronide Sodium Salt is a (-)-Emtricitabine metabolite. Synonyms: (2R-cis)-[5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl β-D-Glucopyranosiduronic Acid Sodium Salt. Molecular formula: C14H17FN3NaO9S. Mole weight: 445.35.
Emtricitabine O-p-Toluenesulfonate
Emtricitabine O-p-Toluenesulfonate is a derivative of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Molecular formula: C15H16FN3O5S2. Mole weight: 401.43.
Emtricitabine Phosphonic Acid Triethylammonium Salt
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: 5-fluoro-1-[(2R,?5S)?-2-(hydroxymethyl)?-1,?3-oxathiolan-5-yl]?-, rel- 2,?4(1H,?3H)?-Pyrimidinedione. Grade: > 95%. CAS No. 3790-05-0. Molecular formula: C8H9FN2O4S. Mole weight: 248.23.
Emtricitabine Related Impurity 2
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: 4-amino-5-fluoro-1-[(2R,?4R)?-2-(hydroxymethyl)?-1,?3-dioxolan-4-yl]?-2(1H)?-Pyrimidinone. Grade: > 95%. CAS No. 145417-33-0. Molecular formula: C8H10FN3O4. Mole weight: 231.19.
Emtricitabine Related Impurity 3
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: 4-amino-5-fluoro-1-[(2R,?4R)?-2-carboxylic acid-1,?3-dioxolan-4-yl]?-2(1H)?-Pyrimidinone. Grade: > 95%. Molecular formula: C8H8FN3O5. Mole weight: 245.17.
Emtricitabine Related Impurity 4
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: (3R,6R,10R,10aS)-7-amino-10-fluoro-2,3,6,6a,10,10a-hexahydro-3,6-epoxy[1,4]oxathiocino[7,8-c]pyridin-9(5H)-one. Grade: > 95%. Molecular formula: C9H11FN2O3S. Mole weight: 246.26.
Emtricitabine Related Impurity 5
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: (3R,6R,10R,10aS)-10-fluorohexahydro-3,6-epoxy[1,4]oxathiocino[7,8-c]pyridine-7,9(5H,8H)-dione. Grade: > 95%. Molecular formula: C9H11FN2O3S. Mole weight: 246.26.
Emtricitabine R-sulfoxide
An impurity of Emtricitabine, a nucleoside reverse-transcriptase inhibitor used to treat HBV and HIV infection. Synonyms: (R)-emtricitabine sulfoxide. Molecular formula: C8H10FN3O4S. Mole weight: 263.25.
Emtricitabine S-oxide
Emtricitabine, a potent nucleoside reverse transcriptase inhibitor, is employed for managing HIV infection. Emtricitabine S-oxide, also known as Emtricitabine sulfoxide, represents a significant degradation byproduct of Emtricitabine. Category: Active pharmaceutical ingredients. Synonyms: Emtricitabine Degradant-III, Emtricitabine sulfoxide. CAS No. 152128-77-3. Product ID: API152128773. Molecular formula: C8H10FN3O4S. Mole weight: 263.25.
Emtricitabine S-Oxide
A metabolite of Emtricitabine. Synonyms: 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,5α)]-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; [2R-(2α,5α)]-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-3-oxido-1. Grade: > 95%. CAS No. 152128-77-3. Molecular formula: C8H10FN3O4S. Mole weight: 263.25.
Emtricitabine S-sulfoxide
An impurity of Emtricitabine, a nucleoside reverse-transcriptase inhibitor used to treat HBV and HIV infection. Synonyms: Emtricitabine S-oxide, (S)-; Emtricitabine sulfoxide, (S)-; Emtricitabine 3'-oxide, (S)-. CAS No. 1160303-44-5. Molecular formula: C8H10FN3O4S. Mole weight: 263.25.
Emtricitabine (Standard)
Emtricitabine (Standard) is the analytical standard of Emtricitabine. This product is intended for research and analytical applications. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BW1592 (Standard). CAS No. 143491-57-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17427R.
Emtricitabine Tenofovir Alfenamide
Emtricitabine Tenofovir Alfenamide is a derivative of Emtricitabine, which is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: Emtricitabine Tenofovir Alfenamide Mixed Dimer Impurity; Isopropyl (((((R)-1-(6-((((5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate; (2S)-Isopropyl 2-((((((2R)-1-(6-((((5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate; Isopropyl N-[({[(2R)-1-(6-{[({5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-1,2-dihydro-4-pyrimidinyl}amino)methyl]amino}-9H-purin-9-yl)-2-propanyl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate; L-Alanine, N-[[[(1R)-2-[6-[[[[5-fluoro-1,2-dihydro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-4-pyrimidinyl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester. Grade: >95%. Molecular formula: C30H39FN9O8PS. Mole weight: 735.72.
Emtricitabine Tenofovir Disoproxil Dihydrochloride is a derivative of Emtricitabine. Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. Synonyms: Emtricitabine Tenofovir FT6 IMP dihydrochloride; ((((((R)-1-(6-((((5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) Diisopropyl Dicarbonate dihydrochloride; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[5-fluoro-1,2-dihydro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-4-pyrimidinyl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, dihydrochloride; Tenofovir dipivuroxime enrutabine adduct dihydrochloride; Emtricitabine Tenofovir Disoproxil Dimer dihydrochloride. Grade: 90%. Molecular formula: C28H40FN8O13PS.2HCl. Mole weight: 851.62.
Emtricitabine Tenofovir Disoproxil Dimer
Emtricitabine Tenofovir Disoproxil Dimer is a derivative of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: Emtricitabine Tenofovir FT6 IMP; ((((((R)-1-(6-((((5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) Diisopropyl Dicarbonate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[5-fluoro-1,2-dihydro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-4-pyrimidinyl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide; Tenofovir dipivuroxime enrutabine adduct; Emtricitabine Tenofovir Disoproxil. Grade: >95%. CAS No. 1962114-98-2. Molecular formula: C28H40FN8O13PS. Mole weight: 778.71.
Emtricitabine Tenofovir FT1 IMP
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment and prevention of HIV-1 infection. Synonyms: Phosphonic acid, P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, mono[[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] ester; [(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl hydrogen P-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonate; Emtricitabine Impurity 19; Emtricitabine FT1. Grade: ≥95%. CAS No. 1962114-95-9. Molecular formula: C17H22FN8O6PS. Mole weight: 516.44.
Emtricitabine Tenofovir FT2 IMP
An impurity of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) used in the treatment and prevention of HIV-1 infection. Synonyms: P-[[(1R)-2-[6-[[[[5-Fluoro-1,2-dihydro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-4-pyrimidinyl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]phosphonic acid; Emtricitabine Impurity 18. Grade: ≥95%. CAS No. 1962115-01-0. Molecular formula: C18H24FN8O7PS. Mole weight: 546.47.
Emtricitabine Tenofovir Monosoproxil
Emtricitabine Tenofovir Monosoproxil is a derivative of Emtricitabine. Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. Synonyms: ((((((R)-1-(6-((((5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl Isopropyl Carbonate. Grade: 95%. Molecular formula: C23H32FN8O10PS. Mole weight: 662.58.
Emtricitabine Tenofovir Monosoproxil Dimer
Emtricitabine Tenofovir Monosoproxil Dimer is a derivative of Emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: Emtricitabine Tenofovir Monosoproxil; Emtricitabine Tenofovir FT5 IMP; ((((((R)-1-(6-((((5-Fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate; 2,4,7-Trioxa-5-phosphanonanoic acid, 9-[6-[[[[5-fluoro-1,2-dihydro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-oxo-4-pyrimidinyl]amino]methyl]amino]-9H-purin-9-yl]-5-hydroxy-8-methyl-, 1-methylethyl ester, 5-oxide, (8R)-. Grade: >95%. CAS No. 1962115-00-9. Molecular formula: C23H32FN8O10PS. Mole weight: 662.60.
Emtricitabine Thioacetate
Emtricitabine Thioacetate is synthesized from emtricitabine. Emtricitabine is a nucleoside reverse transcriptase inhibitor for the treatment of HIV infection in adults and children. Synonyms: S-(((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl) Ethanethioate. Grade: > 95%. Molecular formula: C10H12FN3O3S2. Mole weight: 305.35.
Emtricitabine triphosphate
(-)-Emtricitabine triphosphate, an antiviral drug, is commonly prescribed for HIV-1 infection. It suppresses virus replication by inhibiting the reverse transcriptase enzyme. Consequently, the viral load decreases, and immune efficacy increases, delaying the onset of AIDS. Synonyms: EMTRICITABINE TRIPHOSPHATE; CHEMBL341421; 145819-92-7; EMTRICITABINE 5'-TRIPHOSPHATE; [[(2r,5s)-5-(4-Azanyl-5-Fluoranyl-2-Oxidanylidene-Pyrimidin-1-Yl)-1,3-Oxathiolan-2-Yl]methoxy-Oxidanyl-Phosphoryl] Phosphono Hydrogen Phosphate; ((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl tetrahydrogen triphosphate; [(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl tetrahydrogen triphosphate; 1RY; L-FSddCTP; Emtricitabine Triphosphate Sodium Salt; Discontinued See E525075; (-)-FTCTP; (-)-FTC-TP; BDBM50138405; HY-131596; CS-0137524; Q27452391; (-)-2',3'-Deoxy-5-fluoro-3'-thiacytidine-5'-triphosphate; EMTRICITABINE METABOLITE (EMTRICITABINE 5'-TRIPHOSPHATE); ((2R,5S)-5-(4-Amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltetrahydrogentriphosphate; [[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate; TRIPHOSPHORIC ACID, P-(((2R,5S)-5-(4-AMINO-5-FLUORO-2-OXO-1(2H)-PYRIMIDINYL)-1,3-OXATHIOLAN-2-YL)METHYL) ESTER. CAS No. 145819-92-7. Molecular formula: C8H13FN3O12P3S. Mole weight: 487.19.
Emtricitabine triphosphate
Emtricitabine triphosphate ((-)-Emtricitabine triphosphate), the phosphorylated anabolite of Emtricitabine, is a nucleoside reverse transcriptase inhibitor and antiretroviral agent effective against HIV and HBV. Category: Active pharmaceutical ingredients. CAS No. 145819-92-7. Product ID: API145819927. Molecular formula: C8H13FN3O12P3S. Mole weight: 487.19.
Emtricitabine triphosphate tetrasodium salt
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However, Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427), a nucleoside reverse transcriptase inhibitor, targeting to HIV and HBV[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Emtricitabine triphosphate tetrasodium salt. CAS No. 1188407-46-6. Pack Sizes: 1 mg (100 mM * 17 μL in Water); 5 mg (100 mM * 87 μL in Water); 10 mg (100 mM * 174 μL in Water); 25 mg (100 mM * 435 μL in Water). Product ID: HY-131596B.
Emtricitabine triphosphate tetrasodium salt
(-)-Emtricitabine triphosphate sodium salt is robustly categorized as an efficacious nucleoside reverse transcriptase inhibitor, illuminating its legalizing role in the therapeutic research against HIV infection. It can seize upon the function of HIV reverse transcriptase to lay siege to the viral replication behavior, thus endeavoring to strike back effectively against this malady. Uses: A metabolite of (-)-emtricitabine (e525000). Synonyms: 1188407-46-6; (-)-EMTRICITABINE TRIPHOSPHATE TETRASODIUM SALT; Sodium ((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl triphosphate; tetrasodium; [[[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate; Sodium((2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyltriphosphate. Grade: ≥ 95% (HPLC). CAS No. 1188407-46-6. Molecular formula: C8H9FN3Na4O12P3S. Mole weight: 575.11.
Emtricitabine Triphosphate Triethylammonium Salt
Emtricitabine Triphosphate Triethylammonium Salt is a metabolite of (-)-Emtricitabine. Synonyms: Triphosphoric Acid P-[[(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Triethylammonium Salt; Triphosphoric Acid (2R-cis)-P-[[5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Triethylammonium Salt; Emtricitabine 5'-Triphosphate Triethylammonium Salt; (-)-FTC-Triphosphate. Grade: 96%. Molecular formula: C8H13FN3O12P3S 3C6H15N. Mole weight: 487.19.
Emtricitabine Triphosphate Triethylammonium Salt
Emtricitabine Triphosphate Triethylammonium Salt is a metabolite of (-)-Emtricitabine (E525000). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C8H13FN3O12P3S 3(C6H15N). US Biological Life Sciences.
Worldwide
Emugrobart
Emugrobart (GYM-329, RG6237, RG-70240) is a humanized IgG1κ antibody targeting myostatin (Myostatin; GDF8). Emugrobart binds to pro-myostatin and latent myostatin, blocking their cleavage into mature myostatin; it also has a clearance function, which transports bound myostatin for degradation and allows for cyclic reuse. Emugrobart enhances muscle strength in mouse models of muscle atrophy and increases muscle mass in cynomolgus monkeys. Emugrobart can be used in research on spinal muscular atrophy and facioscapulohumeral muscular dystrophy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GYM-329, RG6237, RG-70240. CAS No. 2922218-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990993.
Emunkitug
HY-P990994 is an TNFRSF1B-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HFB-200301. CAS No. 2916519-48-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990994.
Emvistegrast
Emvistegrast (GS-1427) is a quinolone derivative. Emvistegrast is also an inhibitor of α4β7 integrin. Emvistegrast can be used to investigate diseases mediated by α4β7 integrin, such as inflammatory bowel disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-1427. CAS No. 2417352-91-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-177080.
Emylcamate
Emylcamateis an anxiolytic and muscle relaxant. It can be used for the treatment of anxiety and tension. Uses: Treatment of anxiety and tension. Synonyms: Emylcamate; Emilcamato; Emylcamat; Nuncital; Psicoplegil; Restetal; Stratran; Striatan; Striatran; Statran; KABI-925; Kabi-295; tert-Hexyl carbamate; MK-250; 1-Ethyl-1-methylpropyl carbamate. Grade: 98%. CAS No. 78-28-4. Molecular formula: C7H15NO2. Mole weight: 145.20.
Emzadirib
Emzadirib (RAD51-IN-2) is a RAD51 inhibitor extracted from patent WO2019/051465A1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CYT-0851; RAD51-IN-2. CAS No. 2301085-04-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111887.
EN1033
EN1033 is a covalent immune regulatory transcription factor 5/8 (IRF5/8) molecular glue degrader. EN1033 degrades IRF5 in a proteasome-dependent manner. EN1033 engages and degrades IRF8 more robustly and rapidly. EN1033 covalently targets C28 and C223 to destabilize and degrade IRF5 and IRF8 respectively, thereby inhibiting their pro-inflammatory transcriptional activity. EN1033 serves as a promising tool for the study of autoimmune and inflammatory disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2193367-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175759.
EN106
EN106 is a potent inhibitor of FEMIB. EN106 is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1. EN106 reduces oxidative stress and rescues high glucose-induced impaired angiogenesis in HUVECs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 757192-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W229874.
EN106
EN106 is a FEM1B inhibitor that acts as a cysteine-reactive covalent ligand. Synonyms: EN-106; EN 106; 2-chloro-N-(2-cyanoethyl)-N-2,3-dihydro-1,4-benzodioxin-6-ylacetamide. Grade: 98% by HPLC. CAS No. 757192-67-9. Molecular formula: C13H13ClN2O3. Mole weight: 280.70.
EN1441
EN1441 is a covalent degrader targeting the androgen receptor (AR) with an EC50 value of 4.2 μM and its truncated variant AR-V7. EN1441 selectively and potently degrades both AR and AR-V7 in androgen-independent prostate cancer cells. EN1441 is promising for research of androgen-independent prostate cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2196448-47-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173626.
EN219
EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380351-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115715.
EN4
EN4 is a covalent ligand that targets cysteine 171 (C171) of MYC. EN4 is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197824-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134761.
EN40
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2094547-67-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122577.
EN460
EN460 is a selective endoplasmic reticulum oxidation 1 (ERO1) inhibitor. EN460 (IC50 of 1.9 μM) interacts selectively with the reduced, active form of ERO1α and prevents its reoxidation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 496807-64-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12837.
EN460
EN460 is a small molecule inhibitor by EN460 binding to ERO1α to promote the loss of flavin adenine dinucleotide (FAD) from the holoenzyme(IC50=1.9 uM). Uses: Ero1 inhibitor ii. Synonyms: EN460; EN-460; EN 460. 2-chloro-5-[5-oxo-4-[(5-phenyl-2-furyl)methylene]-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid. Grade: ≥98%. CAS No. 496807-64-8. Molecular formula: C22H12ClF3N2O4. Mole weight: 460.79.
EN523
EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2094893-05-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143345.
EN6
EN6 is a novel covalent autophagy activator and targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase with an IC50 of 1.7 μM for recombinant human ATP6V1A protein. Group: Inhibitors. CAS No. 1808714-73-9. Pack Sizes: 5mg. Product ID: S6650. Formula: C19H14F2N4O2. Smiles: C=CC(=O)NC1=C(C=CC(=C1)NC(=O)C2=CN(N=C2)C3=CC=CC=C3F)F. Storage Conditions: 3 years -20°C powder.
United States; Europe
EN6
EN6 is a novel covalent autophagy activator that targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase with IC50 of 1.7 μM for recombinant human ATP6V1A protein. Synonyms: EN 6; EN6. CAS No. 1808714-73-9. Molecular formula: C19H14F2N4O2. Mole weight: 368.34.
EN6
EN6 is a small-molecule in vivo autophagy activator that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal v-ATPase. EN6-mediated modification of ATP6V1A uncouples v-ATPase from Rag, leading to inhibition of mTORC1 signalling, increased lysosomal acidification, and activation of autophagy. EN6 also scavenges TDP-43 aggregates (causative agents of frontotemporal dementia) in a lysosome-dependent manner[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1808714-73-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128892.
Enactin Ia
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Ia; 19-hydroxyneoenactin B2; (S)-2-Amino-3,N-dihydroxy-N-(15-hydroxy-15-methyl-3,10-dioxo-hexadecyl)-propionamide. CAS No. 130640-30-1. Molecular formula: C20H38N2O6. Mole weight: 402.53.
Enactin Ib
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Ib. CAS No. 137252-26-7. Molecular formula: C20H38N2O6. Mole weight: 402.53.
Enactin-Va
It is produced by the strain of Streptomyces roseoviridis. It has only weak antifungal activity. Synonyms: EN-Va; 14-dihydroneoenactin M1; (S)-2-Amino-3,N-dihydroxy-N-(10-hydroxy-14-methyl-3-oxo-pentadecyl)-propionamide. CAS No. 130640-31-2. Molecular formula: C19H38N2O5. Mole weight: 374.52.
Enacyloxin IIa
It is produced by the strain of Frateuria sp. W-315. It is a polyene antibiotic, which has the activity of anti-gram-positive bacteria and negative bacteria. the activity of anti-fungus is weak, and has no effect on yeast. Synonyms: (1S,3R,4S)-3-{[(2E,4E,6E,8E,10Z,12S,13R,14S,17R,18S,19R,20E)-19-(carbamoyloxy)-11,18-dichloro-13,14,17-trihydroxy-6,12-dimethyl-15-oxotricosa-2,4,6,8,10,20-hexaenoyl]oxy}-4-hydroxycyclohexanecarboxylic acid; Enacyloxin II; Enacyloxin iia; Enx iia. CAS No. 126518-41-0. Molecular formula: C33H45Cl2NO11. Mole weight: 702.62.
Enadoline hydrochloride
Enadolineis a potent selective Opioid kappa receptor agonists originated by Pfizer. However, clinical trials for the treatment of Arrhythmias, Neuroprotection and Pain were discontinued. Uses: Arrhythmias; neuroprotection; pain. Synonyms: UNII-086I9HO04E; CAM 570; CI-977; NIH 10672; CAM570; CI977; NIH10672; CAM-570; CI 977; NIH-10672; 2-(1-benzofuran-4-yl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide; hydrochloride. Grade: 98%. CAS No. 124439-07-2. Molecular formula: C24H33ClN2O3. Mole weight: 432.99.
Enalapril
Enalapril is an angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. Its IC50 values range from 2 to 800 nM. lt belongs to a class of medications called angiotensin converting enzyme inhibitors. pressure. lt decreases levels of angiotensin II leading to less vasoconstriction and decreased blood pressure by inhibiting ACE. lt has been shown to lower the death rate in systolic heart failure. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Uses: Enalapril is used in the treatment of hypertension, congestive heart failure, myocardial infarction, and diabetic nephropathies. lt decreases levels of angiotensin ii leading to less vasoconstriction and decreased blood pressure by inhibiting ace. lt lowers the death rate in systolic heart failure. Synonyms: (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid. Grade: 98 %. CAS No. 75847-73-3. Molecular formula: C20H28N2O5. Mole weight: 376.45.
Enalapril
Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-421. CAS No. 75847-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-B0331.
Enalapril Acyl Glucuronide
An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Synonyms: (2S,3S,4S,5R,6S)-6-(((S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carbonyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grade: > 95%. Molecular formula: C26H36N2O11. Mole weight: 552.58.
Enalaprilat
Enalaprilat (MK-422 anhydrous), the active metabolite of the oral proagent Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor, with an IC50 of 1.94 nM. Enalaprilat can be used for the research of hypertension[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-422 anhydrous. CAS No. 76420-72-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0231A.
Enalaprilat
Enalaprilat is the active metabolite of enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: Enalaprilic Acid; N-[(1S)-1-(Carboxy)-3-phenylpropyl]-L-alanyl]-L-proline Dihydrate; Enalapril maleate impurity C. Grade: > 95%. CAS No. 76420-72-9. Molecular formula: C18H24N2O5. Mole weight: 348.40.
Enalaprilat Acyl Glucuronide
An impurity of Enalapril. Enalapril is an angiotensin-converting-enzyme inhibitor used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. Synonyms: (2S,3S,4S,5R,6S)-6-(((S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carbonyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grade: > 95%. Molecular formula: C24H32N2O11. Mole weight: 524.53.
Enalaprilat benzyl ester
Enalaprilat benzyl ester. Group: Biochemicals. Alternative Names: N-[ (1S) -3-Phenyl-1-[ (phenylmethoxy) carbonyl]propyl]-L-alanyl-L-proline; (S) -1-[N-[3-Phenyl-1-[ (phenylmethoxy) carbonyl]propyl]-L-alanyl]-L-proline. Grades: Highly Purified. CAS No. 76391-33-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C25H30N2O5. US Biological Life Sciences.
Worldwide
Enalaprilat-d5
Enalaprilat-d5 is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-422 d5. CAS No. 349554-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0231AS.