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| Product | Description | |
|---|---|---|
| Endotoxin Substrate | Endotoxin Substrate is a chromogenic substrate for horseshoe crab clotting enzyme, which is used in quantitative assays of endotoxin. Synonyms: Boc-LGR-pNA. CAS No. 68223-96-1. Molecular formula: C25H40N8O7. Mole weight: 564.63. |  |
| Endotrophin (mouse) | Endotrophin, a carboxy-terminal cleavage product of the collagen 6α-3 chain produced and released by adipocytes, is greatly upregulated in malignant tumors of the breast, liver colon and pancreas. Endotrophin provides a link between obesity and aggressive tumor growth and may serve as a sensitive diagnostic marker and effective therapeutic target for designing better treatments for cancer and improving obesity-induced insulin resistance. Synonyms: H-Thr-Glu-Pro-Leu-Phe-Leu-Thr-Lys-Thr-Asp-Ile-Cys-Lys-Leu-Ser-Arg-Asp-Ala-Gly-Thr-Cys-Val-Asp-Phe-Lys-Leu-Leu-Trp-His-Tyr-Asp-Leu-Glu-Ser-Lys-Ser-Cys-Lys-Arg-Phe-Trp-Tyr-Gly-Gly-Cys-Gly-Gly-Asn-Glu-Asn-Arg-Phe-His-Ser-Gln-Glu-Glu-Cys-Glu-Lys-Met-Cys-Ser-Pro-Glu-Leu-Thr-Val-OH (Disulfide bridge: Cys12-Cys62, Cys21-Cys45, Cys37-Cys58, air oxidized). Grade: ≥95%. CAS No. 1678414-54-4. Molecular formula: C345H520N92O106S7. Mole weight: 7876.94. | |
| Endovion | Endovion is a pharmacological anion channe inhibitor and a volume regulated anion channel (VRAC) blocker. Synonyms: SCO-101; NS 3728; NS-3728; NS3728. CAS No. 265646-85-3. Molecular formula: C16H9BrF6N6O. Mole weight: 495.18. | |
| Endoxifen | Endoxifen. Group: Biochemicals. Grades: Purified. CAS No. 112093-28-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Endoxifen | Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 110025-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719E. |  |
| Endoxifen E-isomer hydrochloride | The hydrochloride salt form of E-isomer of Endoxifen which is a significant metamolite of Tamoxifen, could be a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Uses: The hydrochloride salt form of e-isomer of endoxifen which could be a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Synonyms: E-Endoxifen hydrochloride. Grade: 98%. CAS No. 1197194-61-8. Molecular formula: C25H28ClNO2. Mole weight: 409.95. | |
| Endoxifen HCl | Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2. Endoxifen shows anti-estrogenic effects, and decreases the E2-induced PR expression in MCF-7 cells. In vivo, Endoxifen (8 mg/kg, ) inhibits growth of MCF-7 human mammary tumor xenografts in mice. Synonyms: Z-Endoxifen HCl; Z Endoxifen HCl; ZEndoxifen HCl; Z Endoxifen Hydrochloride; ZEndoxifen Hydrochloride. Grade: 98%. CAS No. 1032008-74-4. Molecular formula: C25H28ClNO2. Mole weight: 409.95. | |
| Endoxifen hydrochloride | Endoxifen hydrochloride is a metabolite of Tamoxifen and a selective estrogen receptor modulator (SERM) that inhibits the growth of estrogen-stimulated BT474 cells (IC50 = 54 nM). Endoxifen is used for the treatment of estrogen receptor (ER) positive breast cancer. Uses: Anticancer drug. Synonyms: 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-Phenol hydrochloride (1:1). Grade: 99%. CAS No. 1197194-41-4. Molecular formula: C25H28ClNO2. Mole weight: 409.95. | |
| Endoxifen (Z-isomer) | Endoxifen Z-isomer hydrochloride, an orally active Tamoxifen (HY-13757A) metabolite, is a selective estrogen receptor modulator with 100-fold more potency than its parent agent, Tamoxifen. Endoxifen Z-isomer inhibits PKCβ1 kinase activity. Endoxifen Z-isomer attenuates PKCβ1-activated AKTSer473 phosphorylation, diminishes AKT substrate phosphorylation, and induces Apoptosis. Endoxifen Z-isomer exhibits anticancer activity against hormone-resistant metastatic breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112093-28-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18719. | |
| Endoxifen Z-isomer hydrochloride | Endoxifen Z-isomer hydrochloride, an orally active Tamoxifen (HY-13757A) metabolite, is a selective estrogen receptor modulator with 100-fold more potency than its parent agent, Tamoxifen. Endoxifen Z-isomer hydrochloride inhibits PKCβ1 kinase activity. Endoxifen Z-isomer hydrochloride attenuates PKCβ1-activated AKTSer473 phosphorylation, diminishes AKT substrate phosphorylation, and induces Apoptosis. Endoxifen Z-isomer hydrochloride exhibits anticancer activity against hormone-resistant metastatic breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1032008-74-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18719A. | |
| enduracididine β-hydroxylase | Fe2+-dependent enzyme. The enzyme is involved in biosynthesis of the nonproteinogenic amino acid β-hydroxyenduracididine, a component of the mannopeptimycins (cyclic glycopeptide antibiotic), produced by Streptomyces hygroscopicus NRRL 30439. Group: Enzymes. Synonyms: MppO; L-enduracididine,2-oxoglutarate:O2 oxidoreductase (3-hydroxylating). Enzyme Commission Number: EC 1.14.11.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0659; enduracididine β-hydroxylase; EC 1.14.11.40; MppO; L-enduracididine,2-oxoglutarate:O2 oxidoreductase (3-hydroxylating). Cat No: EXWM-0659. |  |
| Enduracidin | Enduracidin (Enramycin) is a polypeptide antibiotic produced by Streptomyces fungicides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Enramycin. CAS No. 11115-82-5. Pack Sizes: 100 mg; 500 mg. Product ID: HY-131093. | |
| Enduracidin | Enduracidin. CAS No. 11115-82-5. Product ID: ACM11115825. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Enduracidin | It is produced by the strain of Streptomyces fungicidicus. Enramycin is a polypeptide antibiotic, and it has anti-gram-positive bacteria and mycobacterium activity. Enramycin is composed of two different compounds: Enramycin A and enramycin B. Synonyms: Enramycin; Enramycin Premix; Enramicina; Enramycinum; Enradin. Grade: >95%. CAS No. 11115-82-5. Molecular formula: C107H138Cl2N26O31 (Enramycin A); C108H140Cl2N26O31 (Enramycin B). Mole weight: 2550.21 (Enramycin A); 2564.24 (Enramycin B). | |
| Enduracidin A | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: 1-Oxa-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-pentadecaazacyclononatetracontane, enduracidin A derivative; [1(Z,E),10(R),15(R)]-N-(10-Methyl-1-oxo-2,4-undecadienyl)-L-α-aspartyl-L-threonyl-D-2-(4-hydroxyphenyl)glycyl-D-ornithyl-D-allothreonyl-L-2-(4-hydroxyphenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-L-allothreonyl-N5-(aminocarbonyl)-L-ornithyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-D-alanyl-L-2-(4-hydroxyphenyl)glycyl-D-seryl-L-2-(3,5-dichloro-4-hydroxyphenyl)glycylglycyl-3-(2-amino-4,5-dihydro-1H-imidazol-4-yl)-L-alanyl-D-alanyl-L-2-(4-hydroxyphenyl)glycine 1-lactone; Enramycin A. Grade: >95%. CAS No. 34438-27-2. Molecular formula: C107H138Cl2N26O31. Mole weight: 2355.30. | |
| Enduracidin A hydrochloride | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Enduracidin A HCl; Enramycin A hydrochloride. CAS No. 33368-20-6. Molecular formula: C107H138Cl2N26O31.HCl. Mole weight: 2391.76. | |
| Enduracidin B | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Enramycin B. Grade: 85%. CAS No. 34304-21-7. Molecular formula: C108H140Cl2N26O31. Mole weight: 2369.32. | |
| Enduracidin B hydrochloride | It is produced by the strain of Streptomyces fungicidicus. It has anti-gram-positive bacteria and mycobacterium activity. Synonyms: Enduracidin B HCl; Enramycin B hydrochloride. CAS No. 34765-98-5. Molecular formula: C108H140Cl2N26O31.HCl. Mole weight: 2405.78. | |
| Enduracidin hydrochloride (Enramycin) | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C107H138Cl2N26O31. CAS No. 11115-82-5. Prepack ID 53593712-1g. Molecular Weight 2355.3. See USA prepack pricing. |  |
| Endusamycin | Endusamycin is produced by the strain of Streptomyces endus subsp. aureus. It has activity against gram-positive bacteria, some anaerobic bacteria, Eimeria tenella, E.acervulina. The feed with mycorycin of 10-40 μg/g was effective for coccidioides infection. Synonyms: Dianemycin, 19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-15-((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-, (15(2S,5S,6R))-. CAS No. 100242-41-9. Molecular formula: C47H78O14. Mole weight: 867.11. | |
| Ene Reductases | asymmetric double bond reduction. Group: Enzymes. Synonyms: Ene Reductases; ERED. Form: 1. Enzyme Powder: 29 items*50mg / item, or other quantity2. Screening Kit: 29 items*1mg / item. Ene Reductases; ERED; Screening Kit; library of enzyme; enzyme library. Cat No: ENLC-006. | |
| Enerisant | This active molecular is a histamine H3 receptor antagonist. The IC50 of Enerisant is 4.9 nM in H3 receptor binding assay using (R)-α-methyl[3H]histamine. In the future, Enerisant may be able to applicate to the treatment of Alzheimer's disease, schizophrenia and so on. Uses: The treatment of alzheimer's disease, schizophrenia and so on. Synonyms: [1-[4-[3-[(2R)-2-methylpyrrolidin-1-yl]propoxy]phenyl]pyrazol-4-yl]-morpholin-4-ylmethanone. Grade: 98%. CAS No. 1152747-82-4. Molecular formula: C22H30N4O3. Mole weight: 398.51. | |
| Enflicoxib | Enflicoxib is a non-steroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2), but does not inhibit cyclooxygenase-1 (COX-1). It has anti-inflammatory, analgesic and antipyretic activities in animal models. Synonyms: E 6087; Benzenesulfonamide, 4-[5-(2,4-difluorophenyl)-4,5-dihydro-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 1-(4-Aminosulfonylphenyl)-5-(2,4-difluorophenyl)-4,5-dihydro-3-trifluoromethyl-1H-pyrazole; 4-(5-(2,4-difluorophenyl)-3-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide. Grade: ≥98%. CAS No. 251442-94-1. Molecular formula: C16H12F5N3O2S. Mole weight: 405.34. | |
| Enflicoxib | Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 (COX-2).?Enflicoxib does not inhibit cyclooxygenase-1 (COX-1). E-6087 shows anti-inflammatory, analgesic and antipyretic activities in animal models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E 6087. CAS No. 251442-94-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19384. | |
| Enflurane | Enflurane (Efrane), a volatile anaesthetic, is a potent inhibitor of high conductance Ca2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry. It allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate. Category: Active pharmaceutical ingredients. CAS No. 13838-16-9. Product ID: API13838169. Molecular formula: C3H2ClF5O. Mole weight: 184.49. |  |
| Enflurane | Enflurane. Group: Biochemicals. Alternative Names: 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; 4-Chloro-1H,4H-perfluoro(2-oxabutane). Grades: Highly Purified. CAS No. 13838-16-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C3H2ClF5O. US Biological Life Sciences. | Worldwide |
| Enfortumab | Enfortumab is a humanized derived anti-Nectin-4 antibody that can be conjugated with the highly efficient microtubule disruptor MMAE (HY-15162) to generate the antibody drug conjugate (ADC) Enfortumab vedotin-ejfv (HY-P99016A). Enfortumab can be used for the study of locally advanced and metastatic urothelial carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1448664-46-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99016. | |
| Enfortumab | Enfortumab is a monoclonal antibody targeting Nectin-4. Enfortumab has been used for the treatment of urothelial cancer. CAS No. 1448664-46-7. | |
| Enfortumab (Anti-Nectin-4) | Enfortumab (Anti-Nectin-4) is a monoclonal antibody targeting Nectin-4 and has potential for research into urothelial cancer. MW: 145.44 kD. Group: Antibodies. CAS No. 1448664-46-7. Pack Sizes: 1mg. Product ID: A2392. Storage Conditions: Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |  United States; Europe |
| Enfortumab vedotin-ejfv | Enfortumab vedotin-ejfv is an anti-Nectin-4 antibody-drug conjugate. Enfortumab vedotin-ejfv is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable Val-Cit linker. The antibody portion is Enfortumab (HY-P99016), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346452-25-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99016A. | |
| Enfortumab vedotin-ejfv | Enfortumab vedotin-ejfv is a first-in-class monoclonal antibody drug conjugate that binds Nectin-4, a protein expressed on bladder cancer cells, and delivers the tubulin toxin, monomethyl auristatin E, into the cell causing cell death. Enfortumab vedotin-ejfv was approved by FDA for the treatment of locally advanced or metastatic urothelial cancer. Synonyms: Padcev. CAS No. 1346452-25-2. | |
| Enfortumab vedotin-ejfv | Enfortumab vedotin-ejfv (Padcev) is an antibody-drug conjugate (ADC) composed of an fully human anti-Nectin-4 IgG1 kappa monoclonal antibody (AGS-22C3), conjugated to Monomethyl Auristatin E (MMAE), via a protease-cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl. Enfortumab vedotin-ejfv has the potential for use in research of urothelial carcinoma. Alternative Names: Padcev. CAS No. 1346452-25-2. Pack Sizes: 1mg. Product ID: D4053. Formula: 3.6. Storage Conditions: Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Enfortumab vedotin-ejfv (solution) | Enfortumab vedotin-ejfv (solution) is an anti-Nectin-4 antibody-drug conjugate (ADC). Enfortumab vedotin-ejfv (solution) is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable Val-Cit linker. The antibody portion is Enfortumab (HY-P99016), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv (solution) is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346452-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99016B. | |
| Enfumafungin | Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 260979-95-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8537. | |
| Enfumafungin | Enfumafungin is a triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. Enfumafungin is an antifungal agent that acts on fungal cell walls as an inhibitor of (1,3)-beta-D-glucan synthase. It is specific for yeast and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis. Synonyms: 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 14-(acetyloxy)-8-[(1R)-1,2-dimethylpropyl]-15-(β-D-glucopyranosyloxy)-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-4-hydroxy-1,6a,8,10a-tetramethyl-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aS,14R,15R)-. Grade: ≥98%. CAS No. 260979-95-1. Molecular formula: C38H60O12. Mole weight: 708.88. | |
| Enfuvirtide | Enfuvirtide is a biomimetic peptide of HIV-1 fusion inhibitor with CD4+ cells and it is used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus. Synonyms: N-Acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histidyl-L-seryl-L-leucyl-L-isoleucyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-asparaginyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-leucyl-L-α-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-L-phenylalaninamide; DP 178; ENF; Fuzeon; GP 41-127-162AA; Pentafuside; T 20; T 20 (peptide); Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2. Grade: ≥98%. CAS No. 159519-65-0. Molecular formula: C204H301N51O64. Mole weight: 4491.88. | |
| Enfuvirtide | Enfuvirtide (T20;DP178) is an anti-HIV-1 fusion inhibitor peptide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: T20; DP178. CAS No. 159519-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0052. | |
| Enfuvirtide | Enfuvirtide is an anti-HIV-1 fusion inhibitor peptide. Category: Active pharmaceutical ingredients. CAS No. 159519-65-0. Product ID: API159519650. Molecular formula: C204H301N51O64. Mole weight: 4491.88. | |
| Enfuvirtide Acetate | Enfuvirtide (T20; DP178) acetate is an anti-HIV-1 fusion inhibitor peptide. Uses: An antiretroviral drug used to treat hiv infection. Synonyms: L-Phenylalaninamide, N-acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histidyl-L-seryl-L-leucyl-L-isoleucyl-L-α-glutamyl-L-α-glutamyl-L-seryl-L-glutaminyl-L-asparaginyl-L-glutaminyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-asparaginyl-L-α-glutamyl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-leucyl-L-α-glutamyl-L-leucyl-L-α-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparaginyl-L-tryptophyl-, acetate; Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2.CH3CO2H; N-acetyl-L-tyrosyl-L-threonyl-L-seryl-L-leucyl-L-isoleucyl-L-histidyl-L-seryl-L-leucyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-glutaminyl-L-asparagyl-L-glutaminyl-L-glutaminyl-L-alpha-glutamyl-L-lysyl-L-asparagyl-L-alpha-glutamyl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-leucyl-L-alpha-aspartyl-L-lysyl-L-tryptophyl-L-alanyl-L-seryl-L-leucyl-L-tryptophyl-L-asparagyl-L-tryptophyl-L-phenylalaninamide acetic acid. Grade: ≥98%. CAS No. 914454-00-5. Molecular formula: C206H305N51O66. Mole weight: 4552.62. | |
| Engasertib | Engasertib is an orally active highly specific AKT inhibitor with IC50 values of 0.13 μM, 0.09 μM and 2.75 μM for AKT1, AKT2 and AKT3, respectively. Engasertib inhibits AKT phosphorylation and modulates downstream signalling in vitro. Engasertib can inhibit cancer cell proliferation and tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALM301. CAS No. 1313439-71-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151504. | |
| Engeletin | Engeletin. Group: Biochemicals. Grades: Highly Purified. CAS No. 572-31-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| Engeletin | Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects. Uses: Scientific research. Category: Signaling pathways. CAS No. 572-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0436. | |
| Engeletin | Engeletin is a flavonoid glycoside isolated from the leaves of Engelhardtia roxburghiana Wall. It inhibits a recombinant human aldose reductase. Uses: Anti-inflammatory. Synonyms: Dihydrokaempferol 3-O-a-L-rhamnopyranoside; Engelitin; (2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-3-yl 6-deoxy-a-L-mannopyranoside. Grade: 96.5%. CAS No. 572-31-6. Molecular formula: C21H22O10. Mole weight: 434.39. | |
| Engineering Plastic | Engineering Plastic. |  |
| Engineering plastics | Engineering plastics. | |
| Englerin A | Englerin A is a potent and selective activator of TRPC4 and TRPC5 channels, with EC50s of 11.2 and 7.6 nM, respectively. Englerin A can induce renal carcinoma cells death by elevated Ca2+ influx and Ca2+ cell overload[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1094250-15-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-133168. | |
| Englitazone sodium | Englitazone sodium is a novel blocker of NSCa and KATP channels. It is an antidiabetic agent. Uses: Englitazone sodium is an antidiabetic agent. Synonyms: CP-72467-2; CP72467-2; (-)-5-(((2R)-2-Benzyl-6-chromanyl)methyl)-2,4-thiazolidinedione, sodium salt; Sodium; 5-[[(2R)-2-benzyl-3,4-dihydro-2H-chromen-6-yl]methyl]-1,3-thiazolidin-3-ide-2,4-dione; 2,4-Thiazolidinedione,5-[[3,4-dihydro-2-(phenylmethyl)-2H-1-benzopyran-6-yl]methyl]-, sodium salt. Grade: >98%. CAS No. 109229-57-4. Molecular formula: C20H18NNaO3S. Mole weight: 375.42. | |
| Englumafusp alfa | Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CD19-4-1BBL; RO7227166; RG6076. CAS No. 2417199-08-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990017. | |
| Enhanced Green Fluorescent Protein (EGFP) (200-208) | Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 323198-39-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2528. | |
| Enhancer of rudimentary homolog | ERH is a small, highly conserved protein that has been found in Sus scrofa. It has antibacterial activity. Synonyms: ERH. | |
| Enibarcimab | Enibarcimab is a humanized monoclonal antibody that has been investigated as a medication for the treatment of acute heart failure and COVID-19. Synonyms: HAM 8101; HAM-8101; HAM8101. CAS No. 2305638-98-4. Molecular formula: C29H36N2O. Mole weight: 428.6. | |
| Enilconazole | Imazalil is an antifungal agent that may have carcinogenic potential. Imazalil also inhibits androgen receptors and aromatase through a mixed competitive/noncompetitive mode in vitro. Synonyms: Imazalil; Deccozil; Bromazil; Fungaflor; Clinafarm; Chloramizol; Fungazil; Magnate; 1-(2-(Allyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; 1-[2-(Allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole. CAS No. 35554-44-0. Molecular formula: C14H14Cl2N2O. Mole weight: 297.18. | |
| Eniluracil | Eniluracil, also known as GW776 and GW776C85, is an orally active and irreversible inhibitor of dihydropyrimidine dehydrogenase. Eniluracil inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil (5-FU) in the liver. Co-administration of ethynyluracil permits the oral administration of 5-FU. Uses: Enzyme inhibitors. Synonyms: 5-ethynyluracil; 5-ethynylpyrimidine-2,4(1H,3H)-dione; 5-Ethynyl-2-hydroxypyrimidin-4(1H)-one; GW776; GW-776; GW 776. CAS No. 59989-18-3. Molecular formula: C6H4N2O2. Mole weight: 136.11. | |
| Eniluracil | Potent inactivator of Dihydropyrimidine dehydrogenase (DPD). Group: Biochemicals. Alternative Names: 5-Ethynyl-2,4(1H,3H)-pyrimidinedione; 5-Ethynyluracil; NSC 687296. Grades: Highly Purified. CAS No. 59989-18-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Eniporide | Eniporide is a potent and selective inhibitor of human Na+/H+ exchanger isoform 1 (NHE-1) (IC50 = 4.5 nM). Synonyms: N-(diaminomethylidene)-2-methyl-5-methylsulfonyl-4-pyrrol-1-ylbenzamide. Grade: ≥95%. CAS No. 176644-21-6. Molecular formula: C14H16N4O3S. Mole weight: 320.4. | |
| Enitociclib | Enitociclib ((+)-BAY-1251152; (+)-VIP152) is a selective CDK9 inhibitor (IC50=3 nM) that inhibits transcriptional elongation by blocking Ser2/Ser5 phosphorylation of RNA polymerase II. Enitociclib specifically depletes key short-lived proteins such as c-MYC, MCL-1 and induces tumor cell apoptosis. Enitociclib also interferes with the production of enhancer RNAs (eRNA) and enhancer-promoter interactions, and downregulates oncogene expression at the epigenetic level. Enitociclib exerts synergistic effects with agents including Bortezomib (HY-10227), Lenalidomide (HY-A0003), Pomalidomide (HY-10984), Venetoclax (HY-15531) and Paclitaxel (HY-B0015), and even reverses paclitaxel resistance. Enitociclib serves as a vital research tool for various malignancies such as double-hit diffuse large B-cell lymphoma, multiple myeloma and pancreatic ductal adenocarcinoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-BAY-1251152; (+)-VIP152; (S)-Enitociclib. CAS No. 1610408-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103019. | |
| Enkelytin | The antibacterial spectrum shows that enkelytin is active against several Gram-positive bacteria including Staphylococcus aureus, but it is unable to inhibit the Gram-negative bacteria growth. | |
| Enlicitide chloride | Enlicitide chloride is an orally active inhibitor for PCSK9 that blocks the interaction between LPL receptor and PSCK9, with an IC50 of 2.5 nM. Enlicitide chloride can be used in the study of cardiovascular diseases such as atherosclerosis, hypercholesterolemia, coronary heart disease, metabolic syndrome, acute coronary syndrome or related cardiovascular and cardiometabolic disorders[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0616 chloride. CAS No. 2407527-16-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P4153. | |
| Enlimomab | Enlimomab is a mouse monoclonal antibody against ICAM-1 and has been observed to inhibit neutrophil adhesion to brain endothelium in vitro. Enlimomab is proved to be beneficial in reducing disease activity in a subset of patients with rheumatoid arthritis. Synonyms: BI-RR 0001; BI RR 0001. Grade: 95%. CAS No. 142864-19-5. | |
| Enlimomab | Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI-RR 0001; Anti-Human IL6 Recombinant Antibody. CAS No. 142864-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99336. | |
| ENMD-1068 | ENMD-1068 is a PAR-2 antagonist. ENMD-1068 inhibits the development of endometriosis in a mouse model. Synonyms: ENMD1068; ENMD 1068; Piperazine, 1-(6-amino-1-oxohexyl)-4-(3-methyl-1-oxobutyl)-. CAS No. 789488-77-3. Molecular formula: C15H29N3O2. Mole weight: 283.41. | |
| ENMD-1068 hydrochloride | ENMD-1068 hydrochloride is a selective antagonist of protease-activated receptor 2 (PAR2) with antiangiogenic and anti-inflammatory activities. It reduces epatic stellate cells (HSCs) activation and collagen expression through the inhibiton of TGF-β1/Smad signal transduction. Grade: 98%. Molecular formula: C15H30ClN3O2. Mole weight: 319.87. | |
| ENMD-1068 hydrochloride | ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. ENMD-1068 hydrochloride also inhibits the proliferation of endometrial cells and induces apoptosis of epithelial cells in the lesion. ENMD-1068 hydrochloride can be used in the study of endometriosis and liver fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2703451-51-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124748A. | |
| ENMD-1198 | ENMD-1198 is an analog of 2-methoxyestradiol (2ME2) with antiproliferative and antiangiogenic activity. ENMD-1198 is a novel tubulin-binding agent that reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells. Synonyms: IRC-110160; 2-methoxyoestra-1,3,5(10),16-tetraene-3-carboxamide. Grade: 98%. CAS No. 864668-87-1. Molecular formula: C20H25NO2. Mole weight: 311.42. | |
| ENMD-2076 | ENMD-2076 is an orally-active, Aurora A/angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD-2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over-expressed in human cancers. ENMD-2076 also targets the VEGFR, Flt-3 and FGFR3 kinases which have been shown to play important roles in the pathology of several cancers. ENMD-2076 has shown promising activity in Phase 1 clinical trials in solid tumor cancers, leukemia, and multiple myeloma. ENMD-2076 is currently in a Phase 2 trial for ovarian cancer, and preclinical and clinical activities are ongoing in assessing the compound's applicability for other forms of cancer. Synonyms: ENMD-2076; ENMD 2076; ENMD2076. CAS No. 934353-76-1. Molecular formula: C21H25N7. Mole weight: 375.47. | |
| ENMD-2076 | ENMD-2076 is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 934353-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10987A. | |
| ENMD-2076 L-(+)-Tartaric acid | ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold more selective for Aurora A than Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2. Synonyms: ENMD-2076 L-(+)-Tartaric acid; ENMD 2076 L-(+)-Tartaric acid; ENMD2076 L-(+)-Tartaric acid. Grade: >98%. CAS No. 1291074-87-7. Molecular formula: C25H31N7O6. Mole weight: 525.56. | |
| ENMD 547 | ENMD 547. Group: Biochemicals. Alternative Names: 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrobromide; 1-(6-Amino-1-oxohexyl)-4-(3-methyl-1-oxobutyl)piperazine monohydrobromide. Grades: Highly Purified. CAS No. 644961-61-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H30BrN3O2. US Biological Life Sciences. | Worldwide |
| Enmein | Enmein is isolated from I. serra with immunosuppressive effect[1]. Uses: Scientific research. Category: Natural products. CAS No. 3776-39-4. Pack Sizes: 1 mg. Product ID: HY-N5028. | |
| Enmein | Enmein is a natural diterpenoid compound found in several plants. Synonyms: Isodonin. Grade: >98%. CAS No. 3776-39-4. Molecular formula: C20H26O6. Mole weight: 362.42. | |
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