A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Eperisone impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026-87-5. Molecular formula: C16H24ClNO. Mole weight: 281.82. Catalog: APB1026875.
Epertinib
Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib; S-22611; S22611; S 22611; (R,Z)-1-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)but-2-yn-1-one O-morpholin-3-ylmethyl oxime; Epertinib; S-222611; S222611; S 222611; 2-Butyn-1-one, 1-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, O-((3R)-3-morpholinylmethyl)oxime, (1Z)-; N-{3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl}- 6-[(1Z)-N-{[(3R)-morpholin-3-yl]methoxy}but- 2-ynimidoyl]quinazolin-4-amine. CAS No. 908305-13-5. Molecular formula: C30H27ClFN5O3. Mole weight: 559.178.
Epertinib hydrochloride
Epertinib, also known as S-222611, is a potent, oral, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, currently under trials in patients with solid tumours. It also inhibited intracellular kinase activity and the growth of EGFR-expressing and HER2-expressing cancer cells. Synonyms: Epertinib HCl; S-222611 hydrochloride; S-222611 HCl. CAS No. 2071195-74-7. Molecular formula: C30H28Cl2FN5O3. Mole weight: 596.48.
Epetirimod
Epetirimod is a small-molecule immune-response modifier intended for the topical treatment of cervical human papilloma virus (HPV) infection and cervical dysplasia. Synonyms: Epetirimod; 227318-71-0; UNII-9P5MH9F521; Epetirimod [USAN:INN]; 851A; S-30563; 9P5MH9F521; 1-(2-Methylpropyl)-1H-imidazo(4,5-c)(1,5)naphthyridin-4-amine; 1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine; 1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine; 851-A; 1H-Imidazo(4,5-c)(1,5)naphthyridin-4-amine, 1-(2-methylpropyl)-; S 30563; Epetirimod [USAN]; EPETIRIMOD [INN]; Epetirimod (INN/USAN); SCHEMBL544542; CHEMBL2103807; DTXSID20177268; UCPMSMNKGXUFCC-UHFFFAOYSA-N; AKOS040751696; TS-08718; D08911; Q27272855. Grade: >98%. CAS No. 227318-71-0. Molecular formula: C23H18F4N6O2S. Mole weight: 518.5.
Epetraborole HCl
This active molecular is a selective leucyl-tRNA synthetase inhibitor under the development of Anacor Pharmaceuticals and GlaxoSmithKline as a novel boron-containing antibiotic. Epetraborole was applicated in treatment of infections caused by multidrug-resistant Gram-negative pathogens. All Clostridium perfringens strains had Epetraborole MICs of >32 μg/ml. In Oct 2012, Phase-II for Urinary tract infections in Russia was discontinued. In Mar 2013, Phase-II for Gram-negative infections in USA was Suspended. Uses: Urinary tract infections;gram-negative infections. Synonyms: UNII-MM0NZY12FA; MM0NZY12FA; SCHEMBL1980656; CHEMBL3527377; 3-[[(3S)-3-(aminomethyl)-1-hydroxy-3H-2,1-benzoxaborol-7-yl]oxy]propan-1-ol; hydrochloride; AN-3365; GSK-052; AN 3365; GSK 052; AN3365; GSK052. Grade: 98%. CAS No. 1234563-16-6. Molecular formula: C11H17BClNO4. Mole weight: 373.52.
Epetraborole hydrochloride
Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2251052 hydrochloride. CAS No. 1234563-16-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12479A.
A pyrrolyl benzoic acid that effectively competes against ephrin-B3 for EphA4 binding as well as against ephrin-A1/-A2/-A3/-A5 for EphA2 and EphA4 binding by targeting EphA2/A4 high affinity ephrin-binding pocket in a reversible manner, exhibiting much reduced or no potency against ephrin-A4 for EphA2/EphA4 binding, ephrin-A5 for EphA3/A5/A6/A7 binding, ephrin-B2 for B1/B2/B3/B4/B6 binding, or ephrin-B2 for EphA4 binding. Shown to inhibit ephrin-A1-induced EphA2 phosphorylation (by 92% at 200uM) and ephrin-A5-induced EphA4 phosphorylation (by 79% at 400uM) in cultures in vitro and prevent ephrin-A5-induced growth cone collapse of neurons in 6-d chicken embryo retina (by 100% at 400uM) ex vivo, as well as rescue human mutant SOD-1 A4V transgene-induced axonopathy in zebrafish embryos (500uM from 6 to 30hpf) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
The product immediately hydrolyses to methylamine and 1-hydroxy-1-phenylpropan-2-one. Acts on a number of related compounds including (-)-sympatol, (+)-pseudoephedrine and (+)-norephedrine. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.18. CAS No. 73508-06-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1499; ephedrine dehydrogenase; EC 1.5.1.18; 73508-06-2. Cat No: EXWM-1499.
Ephedrine Hydrochloride racemic
Ephedrine Hydrochloride racemic. Uses: For analytical and research use. Group: Api standards. Catalog: APS007964. Format: Neat. Shipping: Room Temperature.
Ephedrine hydrochloride (racemic) - Drug Precursor
Ephedrine hydrochloride (racemic) - Drug Precursor. Uses: For analytical and research use. Group: European pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: (1RS,2SR)-2-(methylamino)-1-phenylpropan-1-ol hydrochloride,Ephedrine hydrochloride racemic. CAS No. 134-71-4. IUPAC Name: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;hydrochloride. Molecular formula: C10H15NO.ClH. Mole weight: 201.69. Catalog: APS134714. SMILES: Cl.CN[C@@H](C)[C@H](O)c1ccccc1. Format: Neat. Shipping: Room Temperature.
Ephedrine Sulphate
Ephedrine Sulphate. Uses: For analytical and research use. Group: Api standards; impurity standards; pharmaceutical toxicology. Alternative Names: Pseudoephedrine Imp. A (EP), Ephedrine Sulphate, Pseudoephedrine Hydrochloride Imp. A (EP) as Sulphate,Pseudoephedrine Hydrochloride Imp. A (EP). CAS No. 134-72-5. IUPAC Name: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;sulfuric acid. Molecular formula: 2C10H15NO.H2O4S. Mole weight: 428.54. Catalog: APS134725. SMILES: CN[C@@H](C)[C@H](O)c1ccccc1.CN[C@@H](C)[C@H](O)c2ccccc2.OS(=O)(=O)O. Format: Neat. Shipping: Room Temperature.
Ephrin type-A receptor 3 (356-367) is a truncated fragment of Ephrin type-A receptor 3. Ephrin type-A receptor 3 is a receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Synonyms: EPH-like kinase 4 (356-367); Tyrosine-protein kinase TYRO4 (356-367); Tyrosine-protein kinase receptor ETK1 (356-367).
EPI-001, a selective inhibitor of Androgen Receptor (AR), targets transactivation unit 5 (Tau-5) of the AR. EPI-001 can inhibit transactivation of the AR amino-terminal domain (NTD), with an IC50 of ~6 ?M. EPI-001 is also a selective modulator of PPAR?. EPI-001 is active against castration-resistant prostate cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 227947-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100348.
EPI-001
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ?6 μM and a selective PPAR-gamma modulator. Synonyms: EPI001; EPI 001. Grade: 98%. CAS No. 227947-06-0. Molecular formula: C21H27ClO5. Mole weight: 394.89.
Epi-(26R) Vancomycin B
Epi-(26R) Vancomycin B is the monohydrochloride of Vancomycin. Vancomycin is a glycopeptide antibiotic for the treatment of gram-positive bacteria. Vancomycin exhibits an antibacterial effect by inhibiting bacterial cell wall synthesis. Uses: Anti-bacterial agents. Synonyms: Vancomycin Monohydrochloride; Lyphocin Monohydrochloride; Meek Monohydrochloride; Vancocin Monohydrochloride; Vancocine Monohydrochloride; Vancocyn Monohydrochloride; Vancor Monohydrochloride. CAS No. 197638-25-8. Molecular formula: C66H75Cl2N9O24 HCl. Mole weight: 1485.71.
EPI-589
EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase enzyme inhibitor and a free radical scavenger, with blood-brain barrier permeable and orally available. EPI-589 is a redox-active neuroprotectant that effectively delays the symptoms of motor neuron disease in wobbler mice. EPI-589 can be used in amyotrophic lateral sclerosis (ALS) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1147883-03-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125999.
EPI-743
EPI-743 (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. EPI-743 is a synthetic analog of vitamin E with oral activity, targets repletion of reduced intracellular glutathione [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-Tocotrienol quinone; PTC-743; Vatiquinone; NCT04378075. CAS No. 1213269-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16772.
Epiallopregnanolone
Epiallopregnanolone, a metabolite of progesterone, is a novel derivative of the steroid Dehydroepiandrosterone (DHEA). Epiallopregnanolone is a 3β-isomer of allopregnanolone. Epiallopregnanolone is inactive as a GABAA receptor modulator and is used as a control substance to examine GABA neurotransmission. Synonyms: 5α-Pregnan-20-one; 3β,21-dihydroxy-5α-Pregnan-20-one; 3β,5α-Tetrahydrodeoxycorticosterone; 3β,5α-Tetrahydroprogesterone; 2-hydroxy-1-[(3S,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone. Grade: ≥95%. CAS No. 567-01-1. Molecular formula: C21H34O3. Mole weight: 334.5.
Epiallopregnanolone
Epiallopregnanolone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-ALPHA-PREGNAN-3-BETA, 21-DIOL-20-ONE;3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE;5-A-pregnane-3-B-21-diol-20-one. Product Category: Steroidal Compounds. CAS No. 567-01-1. Molecular formula: C21H34O3. Mole weight: 334.49. Purity: 0.95. IUPACName: 2-hydroxy-1-[(3S,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone. Canonical SMILES: CC12CCC(CC1CCC3C2CCC4(C3CCC4C(=O)CO)C)O. Product ID: ACM567011. Alfa Chemistry ISO 9001:2015 Certified.
It has a role as an androgen and a human metabolite. It is a 17-oxo steroid, a 3beta-hydroxy steroid and an androstanoid. It is functionally related to a 5alpha-androstane. Alternative Names: trans-Androsterone. Isoandrosterone. iso-Androsterone. CAS No. 481-29-8. Product ID: INT481298. Molecular formula: C19H30O2. Mole weight: 290.4. EINECS: 207-563-3. SMILES: C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O. Category: Intermediates.
Epiandrosterone
Epiandrosterone is a steroid hormone with weak androgenic activity. Uses: Scientific research. Group: Natural products. Alternative Names: 3β-Androsterone; trans-Androsterone; iso-Androsterone. CAS No. 481-29-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-I0352.
Epiandrosterone
Epiandrosterone. Group: Biochemicals. Alternative Names: (3b,5a)-3-Hydroxyandrostan-17-one; 3-Epiandrosterone; 3b-Androsterone. Grades: Highly Purified. CAS No. 481-29-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H30O2. US Biological Life Sciences.
5g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C19H30O2. CAS No. 481-29-8. Prepack ID 38816451-5g. Molecular Weight 290.44. See USA prepack pricing.
Epiandrosterone acetate
Epiandrosterone acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-BETA-HYDROXY-5-ALPHA-ANDROSTAN-17-ONE 3-ACETATE;3-BETA-ACETOXY-5-ALPHA-ANDROSTAN-17-ONE;5-EPIANDROSTER-17-ONE ACETATE;5-ALPHA-ANDROSTAN-3-BETA-OL-17-ONE ACETATE;5ALPHA-ANDROSTAN-3BETA-OL-17-ONE 3-ACETATE;ACETIC ACID (3S,5S,8R,9S,10S,13S,14S)-10,13-DIME. Product Category: Steroidal Compounds. Appearance: crystal or stout prism. CAS No. 1239-31-2. Molecular formula: C21H32O3. Mole weight: 332.48. Purity: 98%+. IUPACName: (10,13-dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl) acetate. Density: 1.09 g/cm³. Product ID: ACM1239312. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3beta-Acetoxy-5alpha-androstan-17-one.
Epiandrosterone b-D-glucuronide
Epiandrosterone is an innate steroid hormone, and Epiandrosterone b-D-glucuronide manifests as a glucuronide conjugate. Predominantly employed in the realm of biomedical inquiry, it is used to unravel the intricate web of Epiandrosterone's metabolism and excretion within the corporeal domain. Synonyms: (3b,5a)-17-Oxoandrostan-3-yl b-D-glucopyranosiduronic acid; 17-Oxo-5a-androstan-3b-yl b-D-glucopyranosiduronic acid; 17-Oxo-5a-androstan-3b-yl b-D-glucosiduronic acid. CAS No. 4271-00-5. Molecular formula: C25H38O8. Mole weight: 466.56.
Epianhydrochlortetracycline hydrochloride
A secondary degradation product formed by dehydration of epichlortetracycline at the C6 position to aromatise the B ring. It is an important standard for monitoring tetracycline stability. Synonyms: 4-Epianhydrochlortetracycline hydrochloride; [4R-(4α,4aβ,12aβ)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide Monohydrochloride; 4-Epianhydrochlortetracycline HCl. Grade: >95% by HPLC. CAS No. 158018-53-2. Molecular formula: C22H22Cl2N2O7. Mole weight: 497.33.
epi-Aszonalenin A (Epiaszonalenin A)
Derivative of aszonalenin, a substance P inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 908853-14-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C25H25N3O3. US Biological Life Sciences.
Worldwide
epi-Avermectin B1a
It is a base-catalysed intermediate in the decomposition of avermectin B1a. It has only very weak activity as a nematocide showing 100-fold less of biological activity compared with the parent avermectin. It is an environmental degradation product. Synonyms: Avermectin B1a, epi-; 2-epi-Abamectin; (2S)-5-O-demethyl-avermectin A1a. Grade: >95% by HPLC. CAS No. 106434-14-4. Molecular formula: C48H72O14. Mole weight: 873.08.
Epibatidine
(±)-Epibatidine is a potent nicotinic agonist (Ki = 0.02 and 233 nM for α4β2 and α7 nicotinic receptors, respectively). Uses: Analgesic. Synonyms: Epibatidine; (±)-exo-2-(6-Chloro-3-pyridinyl)-7-azabicyclo[2.2.1.]heptane. CAS No. 140111-52-0. Molecular formula: C11H13ClN2. Mole weight: 208.69.
Epibenzomalvin E
Epibenzomalvin E is a new substance P inhibitor from Penicillium. Grade: >95% by HPLC. Molecular formula: C24H19N3O3. Mole weight: 397.4.
Epiberberine
Epiberberine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6873-9-2. Pack Sizes: 20mg. Molecular Formula: C20H18NO4+, Molecular Weight: 336.36. US Biological Life Sciences.
Worldwide
Epiblastin A
Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Epiblastin A; AUE. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 16470-02-3. Molecular formula: C12H10ClN7. Mole weight: 287.71. Purity: >98%. IUPACName: 6-(3-Chloro-phenyl)-pteridine-2,4,7-triamine. Canonical SMILES: NC1=NC(N)=C2N=C(C3=CC=CC(Cl)=C3)C(N)=NC2=N1. Product ID: ACM16470023. Alfa Chemistry ISO 9001:2015 Certified.
Epiblastin A
Epiblastin A is a Casein Kinase 1 (CK1) inhibitor. It converts epiblast stem cells (EpiSC) into embryonic stem cells (ESC) and enhances ESC self-renewal. Synonyms: Epiblastin A - Bio-X. Grade: >98%. CAS No. 16470-02-3. Molecular formula: C12H10ClN7. Mole weight: 287.711.
Epiboxidine is a potent nicotinic acetylcholine receptor agonist. An analog of epibatidine. Synonyms: exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane hydrochloride. CAS No. 188895-96-7. Molecular formula: C10H15ClN2O. Mole weight: 214.69.
Epibrassinolide
Epibrassinolide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 24-EPIBRASSINOLIDE; Epibrassinolide(24-Epibrassinolide); Brassinolide(epibrassinolide,Homobrassinolide).(22R,23R,24R)-2; BRASSINOLIDE; 4-Epicastasterone; Epibrassinolide; BRASSINOLIDE(BR); 24-(R)-EPIBRASSINOLIDE; 24-Epicastasterone; EPI BRASSINOLIDE; 3.24-EPIBRASSINOLIDE; CH09964 EPIBRASSINOLIDE; 2,4-Epibrassinolide. Product Category: Heterocyclic Organic Compound. CAS No. 78821-43-9. Molecular formula: C28H48O6. Mole weight: 480.68. Purity: 0.9. IUPACName: 24-epi-brassinolide. Canonical SMILES: CC(C)C(C)C(C(C(C)C1CCC2C1(CCC3C2COC(=O)C4C3(CC(C(C4)O)O)C)C)O)O. Product ID: ACM78821439. Alfa Chemistry ISO 9001:2015 Certified.
Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants [1]. Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 24-Epibrassinolide; B1105; BP55. CAS No. 78821-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0848.
Epi-Brassinolide
Brassinosteroids are plant hormones involved in metabolic manipulation and protection from environmental stress. Group: Biochemicals. Alternative Names: 22R,23R,24R-2a,3a,22,23-Tetrahydroxy-B-homo-7-oxa-5a-ergostan-6-one; (1R, 3aS, 3bS, 6aS, 8S, 9R, 10aR, 10bS, 12aS) -1- [ (1S, 2R, 3R, 4R) -2, 3-Dihydroxy-1, 4, 5-trimethylhexyl] hexadecahydro-8, 9-dihydroxy-10a, 12a-dimethyl-6H-benz [c] indeno [5, 4-e] oxepin-6-one. Grades: Highly Purified. CAS No. 78821-43-9. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.