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Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Asp(OtBu)-Wang-PEG Resin; N-α-(9-Fluorenylmethoxycarbonyl)-L-aspartic acid β-t-butyl ester p-methoxybenzyl alcohol polyethyleneglycol resin.
Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction. This derivative also completely inhibits aspartimide formation. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-(Dmb)Gly-OH, N-α-Fmoc-β-O-t.-butyl-L-aspartyl-N-α-(2,4-dimethoxybenzyl)-glycine. Product Category: Amino Acids. CAS No. 900152-72-9. Mole weight: 618.67. Product ID: ACM900152729. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis [1]. Uses: Scientific research. Group: Peptides. Alternative Names: 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH. CAS No. 71989-14-5. Pack Sizes: 100 g; 500 g. Product ID: HY-Y1169.
Fmoc-Asp(OtBu)-OH
High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of aspartic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-OH, N-α-Fmoc-L-aspartic acid β-t.-butyl ester. Product Category: Amino Acids. CAS No. 71989-14-5. Molecular formula: C23H25NO6. Mole weight: 411.45. Product ID: ACM71989145-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Fmoc-L-Asp(OtBu)-OH.
Fmoc-Asp(OtBu)-OH
Fmoc-Asp(OtBu)-OH. Group: Biochemicals. Alternative Names: Fmoc-L-aspartic acid b-tert-butyl ester. Grades: Highly Purified. CAS No. 71989-14-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C23H25NO6. US Biological Life Sciences.
Worldwide
Fmoc-Asp(OtBu)-OH
Fmoc-Asp(OtBu)-OH. CAS No: 71989-14-5
Sarchem Laboratories New Jersey NJ
Fmoc-Asp(OtBu)-OH-[13C4,15N]
Fmoc-Asp(OtBu)-OH-[13C4,15N] is the labelled analogue of Fmoc-L-aspartic acid β-tert-butyl ester. Fmoc-L-aspartic Acid β-tert-butyl Ester is Fmoc protected L-Aspartic Acid 4-tert-Butyl Ester which is a protected form of L-Aspartic acid. L-Aspartic acid is a nonessential amino acid that is used to biosynthesize other amino acids within the human body. Synonyms: DTXSID70745815; Fmoc-Asp(OtBu)-OH-13C4,15N; (2R)-4-tert-Butoxy-2-[{[(9H-fluoren-9-yl)methoxy]carbonyl}(15N)amino]-4-oxo(13C4)butanoic acid. Grade: 97% (CP); 98% atom 15N; 98% atom 13C. CAS No. 1217468-27-3. Molecular formula: C19[13C]4H25[15N]O6. Mole weight: 416.41.
Fmoc-Asp(OtBu)-OH-15N. Uses: Peptide synthesis. Additional or Alternative Names: L-Aspartic-15N acid, N-Fmoc, 4-tert-butyl ester. Product Category: Amino Acids. CAS No. 1217457-38-9. Molecular formula: t-Bu-O2CCCH2CH(15NH-Fmoc)CO2H. Mole weight: 412.44. Canonical SMILES: CC(C)(C)OC(=O)C[C@H]([15NH]C(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O. Product ID: ACM1217457389. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-OH (U-13 C4, 15N)
Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine-protecting group Fmoc. Uses: Fmoc-asp(otbu)-oh can be used for peptide synthesis. Product Category: Amino Acids. CAS No. 1160760-08-6. Molecular formula: (CH3)3COO13C13CH213CH(15NH-Fmoc)13COOH. Mole weight: 416.4. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC(C)(C)O[13C](=O)[13CH2][13C@@H]([13C](=O)O)[15NH]C(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Product ID: ACM1160760086. Alfa Chemistry ISO 9001:2015 Certified.
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asp-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-Ser(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 955048-92-7. Mole weight: 538.59. Product ID: ACM955048927. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asp(OtBu)-Ser[Psi(Me,Me)Pro]-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 955048-92-7. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-Asp(OtBu)-Tcp Resin
Fmoc-Asp(OtBu)-Tcp Resin.
Fmoc-Asp(OtBu)-Thr(psiMe,Mepro)-OH
This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asp-Thr dipeptide motif. It consists of a dipeptide in which the threonine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The threonine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Asp(OtBu)-Thr(psiMe,Mepro)-OH. Product Category: Amino Acids. CAS No. 920519-32-0. Mole weight: 552.62. Product ID: ACM920519320-1. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-Asu(OtBu)-OH. Group: Biochemicals. Alternative Names: N-a- (9-Fluorenyl methoxycarbonyl ) -L-a-aminosuberic acid ω-?-butyl ester. Grades: Highly Purified. CAS No. 276869-41-1. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Fmoc-Asu(OtBu)-OH ≥97% (HPLC)
Fmoc-Asu(OtBu)-OH ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 276869-41-1. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
Fmoc-Aund(11)-Alko Resin
Wang resins are the standard supports for the preparation of peptide acids by the Fmoc batch solid phase synthesis strategy. Fmoc amino acids are pre-loaded to Wang resins so that that epimerization and dipeptide formation are minimized. Synonyms: Fmoc-Aund(11)-Wang Resin; 11-[(9-Fluorenylmethoxycarbonyl)amino]undecanoic acid p-methoxybenzyl alcohol resin.
Fmoc-azetidine-3-carboxylic acid
Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker and also an alkyl chain-based PROTAC linker. Synonyms: Fmoc-3-azetidine carboxylic acid. Grade: ≥ 99% (HPLC). CAS No. 193693-64-0. Molecular formula: C19H17NO4. Mole weight: 323.35.
Fmoc-azetidine-3-carboxylic acid
Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 193693-64-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011277.
Fmoc-azetidine-3-carboxylic acid
Fmoc-azetidine-3-carboxylic acid. Group: Biochemicals. Alternative Names: Fmoc-3-azetidine carboxylic acid. Grades: Highly Purified. CAS No. 193693-64-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-azetidine-3-carboxylic acid, 98.0 +%
Fmoc-azetidine-3-carboxylic acid, 98.0 +%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-azidolysine
A useful tool for the synthesis of branched, side-chain modified and cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-azidolysine. Product Category: Amino Acids. CAS No. 159610-89-6. Molecular formula: C21H22N4O4. Mole weight: 394.42. Product ID: ACM159610896. Alfa Chemistry ISO 9001:2015 Certified.
Fmoc-b-(2-furyl)-D-alanine 99+%
Fmoc-b-(2-furyl)-D-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Fmoc-b-(2-furyl)-L-alanine 99+%
Fmoc-b-(2-furyl)-L-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-b-(2-thienyl)-D-alanine 98+% (HPLC)
Fmoc-b-(2-thienyl)-D-alanine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-b-(2-thienyl)-L-alanine
Fmoc-b-(2-thienyl)-L-alanine. Group: Biochemicals. Alternative Names: Fmoc-3-L-Ala(2-thienyl)-OH. Grades: Highly Purified. CAS No. 130309-35-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C22H19NO4S. US Biological Life Sciences.
Worldwide
Fmoc-b-(2-thienyl)-L-alanine 98+%.
Fmoc-b-(2-thienyl)-L-alanine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-b-(3-thienyl)-D-alanine 99+%
Fmoc-b-(3-thienyl)-D-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
Fmoc-b-(3-thienyl)-L-alanine 98+%
Fmoc-b-(3-thienyl)-L-alanine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-b-alanine 4-alkoxybenzyl alcohol resin
Fmoc-b-alanine 4-alkoxybenzyl alcohol resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Fmoc-b-alanine 99+% (HPLC)
Fmoc-b-alanine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Fmoc-?-(2-pyridyl)-Ala-OH is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group. Uses: Fmoc-β-(2-pyridyl)-ala-oh is an fmoc protected alanine derivative. Additional or Alternative Names: Fmoc-3-(2-pyridyl)-L-alanine. Product Category: Amino Acids. CAS No. 185379-40-2. Molecular formula: C23H20N2O4. Mole weight: 388.4. Canonical SMILES: OC(=O)[C@H](Cc1ccccn1)NC(=O)OCC2c3ccccc3-c4ccccc24. Density: 1.3±0.1 g/cm3. Product ID: ACM185379402. Alfa Chemistry ISO 9001:2015 Certified.