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| Product | Description | |
|---|---|---|
| GW768505A free base | GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501693-25-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125741. |  |
| GW779439X | GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway[1][2]. MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus. Uses: Scientific research. Category: Signaling pathways. CAS No. 551919-98-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103645. | |
| GW788388 | GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, and also inhibits TGF-β type II receptor and activin type II receptor activities, without inhibiting BMP type II receptor. Uses: Scientific research. Category: Signaling pathways. CAS No. 452342-67-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10326. | |
| GW 791343 dihydrochloride | The hydrochlorie salt form of GW791343 that is a non-competitive inhibitor of human P2X7 receptors amd it seems to show species-specific activity which is probably negative allosteric modulators of the human P2X7 receptor and the agonist of the same recep. Uses: The hydrochlorie salt form of gw791343 that is a non-competitive inhibitor of human p2x7 receptors. Alternative Names: GW791343 (dihydrochloride); 1019779-04-4; 2-((3,4-Difluorophenyl)amino)-N-(2-methyl-5-(piperazin-1-ylmethyl)phenyl)acetamide dihydrochloride; GW 791343; GW-791343; 3075AH. Grades: >99 %. CAS No. 1019779-04-4. Molecular formula: C20H26Cl2F2N4O. Mole weight: 447.3. |  |
| Gw 791343 hydrochloride | Gw 791343 hydrochloride. CAS No. 1019779-04-4. Purity: >99 %. Product ID: ACM1019779044. Molecular formula: C20H24F2N4O.3HCl. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| GW 791343 hydrochloride | GW 791343 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 309712-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GW 791343 trihydrochloride | GW791343 HCl is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7. Alternative Names: GW791343; GW 791343; GW-791343; 1019779-04-4. Grades: >98%. CAS No. 309712-55-8. Molecular formula: C20H24F2N4O.3HCl. Mole weight: 483.81. | |
| GW 791343 Trihydrochloride | GW 791343 Trihydrochloride. Group: Biochemicals. Alternative Names: 2-[ (3, 4-Difluorophenyl) amino]-N-[2-methyl-5- (1-piperazinylmethyl) phenyl]acetamide Trihydrochloride. Grades: Highly Purified. CAS No. 1019779-04-4. Pack Sizes: 10mg. Molecular Formula: C20H27Cl3F2N4O, Molecular Weight: 447.35. US Biological Life Sciences. | Worldwide |
| GW806742X | GW806742X, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 μM. GW806742X has activity against VEGFR2 (IC50=2 nM). GW806742X retards MLKL membrane translocation and inhibits necroptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 579515-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112292. | |
| GW 833972A | GW 833972A is a selective CB2 receptor agonist with pEC50 of the human CB2 receptor for GW 833972A of 7.3, and its selectivity for the CB2 receptor is approximately 1000 times higher than that for the CB1 receptor. GW 833972A inhibits induced neuronal depolarization and suppresses coughing caused by citric acid in guinea pig models. GW 833972A can be used for the study of chronic cough[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1092502-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-101765. | |
| GW842166X | GW842166X is a potent and selective cannabinoid receptor 2 (CB2) agonist with IC50 values of 63 and 91 nM for human and rat CB2, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 666260-75-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14167. | |
| GW8510 | GW8510 is a potent cyclin-dependent kinase-2 (CDK2) inhibitor. GW8510 is also a ribonucleotide reductase M2 (RRM2) inhibitor. GW8510 exhibits neuroprotective and anticancer activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 222036-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112358. | |
| GW-870086 | GW-870086 is a glucocorticoid receptor agonist with a pIC50 of 10.1 in A549 cells expressing NF-κB. It can be used as an anti-inflammatory agent. Alternative Names: GW-870086; GW-870086X; 870086; GW870086; GW870086X; GW 870086; GW 870086X. CAS No. 827319-43-7. Molecular formula: C31H39F2NO6. Mole weight: 559.651. | |
| GW9508 | GW9508. Group: Biochemicals. Alternative Names: 4- [ [ (3-Phenoxyphenyl) methyl] amino] benzenepropanoic Acid. Grades: Highly Purified. CAS No. 885101-89-3. Pack Sizes: 5mg. Molecular Formula: C22H21NO3, Molecular Weight: 347.41. US Biological Life Sciences. | Worldwide |
| GW9508 | GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 885101-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15589. | |
| GW9508 | GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, and stimulates insulin secretion in a glucose-sensitive manner. GW9508 is commonly used in the treatment of type 2 diabetes. Alternative Names: GW9508; GW-9508; GW 9508; 3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid. Grades: > 98%. CAS No. 885101-89-3. Molecular formula: C22H21NO3. Mole weight: 347.414. | |
| GW9508 (Standard) | GW9508 (Standard) is the analytical standard of GW9508. This product is intended for research and analytical applications. GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 885101-89-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15589R. | |
| GW9662 | GW9662 is a potent and selective PPARγ antagonist with an IC50 of 3.3 nM, showing 10 and 1000-fold selectivity over PPARα and PPARδ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 22978-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-16578. | |
| GW9662 | GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM in a cell-free assay, with at least 10- to 600-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ. Group: Inhibitors. CAS No. 22978-25-2. Pack Sizes: 10mg. Product ID: S2915. Formula: C13H9ClN2O3. Smiles: C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| GW 9662 | GW 9662. Group: Biochemicals. Grades: Purified. CAS No. 22978-25-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GX-201 | GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1788071-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131870. | |
| GX-674 | GX-674 is a potent, state-dependent, isoform-selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 of 0.1 nM at -40 mV[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432913-36-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123825. | |
| GX-674 | GX-674 is a Nav1.7 antagonist in the aryl sulfonamide class with higher selectivity for Nav1.7 (IC50= 0.1nM) over other Nav subtypes. Nav1.7 is commonly expressed in olfactory epithelium, sympathetic ganglion, and dorsal root ganglion sensory neurons. GX-674 has the potential to alleviate extreme pains. Alternative Names: GX-674; GX674;GX 674; 4-(2-(2-Amino-1H-benzo[d]imidazol-5-yl)-4-chlorophenoxy)-2,5-difluoro-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide. CAS No. 1432913-36-4. Molecular formula: C21H13ClF2N6O3S2. Mole weight: 534.94. | |
| GX-936 | GX-936 (PF-05196233), a potent and Nav1.7-subtype selective inhibitor, binds to the activated state of voltage-sensor domain IV (VSD4)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-05196233. CAS No. 1235406-09-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-123414. | |
| Gyki 47261 dihydrochloride | Gyki 47261 dihydrochloride. Alternative Names: GYKI 47261 DIHYDROCHLORIDE, GYKI 47261, CTK8E9492, (Z)-4-(8-chloro-2-methyl-11H-benzo[e]imidazo[1,2-b][1,2]diazepin-6-yl)aniline dihydrochloride, 220445-20-5. CAS No. 1217049-32-5. Purity: >99 %. Product ID: ACM1217049325. Molecular formula: C18H15ClN4.2HCl. Mole weight: 395.71. IUPAC Name: 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)aniline;dihydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| GYKI 47261 dihydrochloride | GYKI 47261 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1217049-32-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 102771-26-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYKI 52466 dihydrochloride | GYKI 52466 dihydrochloride is an orally active, highly selective and noncompetitive AMPA/kainate receptor antagonist with the IC50 values of 7.5 and 11μM, respectively. GYKI 52466 dihydrochloride has good blood brain barrier permeability and anticonvulsant effect. GYKI 52466 dihydrochloride can be used in Parkinson's disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2319722-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103234A. | |
| GYKI 53655 Hydrochloride | A potent negative allosteric modulator selective for AMPA glutamate receptors (IC50 = 6 and 5uM for GluA1 and GluA4, respectively) over kainate receptors (IC50 = 63 and 32uM for GluK3 and GluK2b/GluK3 receptors. Used as neuroprotectant and anticonvulsant, and a valuable tool for the study of AMPA receptor-mediated processes in vivo. Group: Biochemicals. Alternative Names: LY 300168, GYKI-53655 Hydrochloride, AMPA Glutamate Receptor Antagonist, GYKI 53655 Hydrochloride, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepine Hydrochloride. Grades: Highly Purified. CAS No. 143692-48-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gymnema Extract (Ratio) | Gymnema Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gymnema Extract (Ratio). Cat No: EXTW-070. |  |
| Gymnema Extract (Standard) | Gymnema (Gymnema sylvestre) is an herb native to the tropical forests of southern and central India and Sri Lanka. Applications: Gymnema extract is one of the major botanicals being administered for those suffering from diabetes, in boosting insulin levels and controlling healthy blood sugar levels. it has unique property to directly mask the tongue's ability to taste sweet foods, at the same time suppresses glucose absorption from the intestine. Group: Others. CAS No. 122168-40-5. Purity: 25.0% 75.0% Gymnemic acid HPLC. Mole weight: 806.445257 g/mol. Gymnema Extract (Standard); 122168-40-5; C43H66O14. Cat No: EXTW-004. | |
| Gymnemagenin | Gymnemagenin is a triterpenoid isolated from Gymnema sylvestre, showing antihyperglycemic activity. Alternative Names: Olean-12-ene-3β,16β,21β,22α,23,28-hexol; (3β,4α,16β,21β,22α)-Olean-12-ene-3,16,21,22,23,28-hexol. Grades: 98%. CAS No. 22467-07-8. Molecular formula: C30H50O6. Mole weight: 506.71. | |
| Gymnemagenin | Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 22467-07-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2268. | |
| Gymnemagenin | Gymnemagenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 22467-07-8. Pack Sizes: 10mg. Molecular Formula: C30H50O6, Molecular Weight: 506.72. US Biological Life Sciences. | Worldwide |
| Gymnema sylvestre extract | Gymnema sylvestre extract, derived from the leaves of the Gymnema sylvestre plant, is renowned for its anti-diabetic and blood sugar-regulating properties. The key active compounds in the extract are gymnemic acids, which are responsible for its ability to block the taste of sweetness and reduce sugar absorption in the intestines. Gymnema sylvestre is widely used in traditional medicine to help manage type 2 diabetes, as it can help lower blood sugar levels by increasing insulin secretion and improving insulin sensitivity. Additionally, the extract has anti-inflammatory, antioxidant, and lipid-lowering effects, which contribute to its overall benefits for metabolic health. Gymnema sylvestre is also used to support weight loss by reducing sugar cravings and helping to control appetite. It has been shown to help improve cholesterol levels and support heart health as well. Gymnema sylvestre is commonly used in supplements for blood sugar management, weight loss, and overall metabolic support. Uses: Anti-diabetic agents, kidney care agents. Alternative Names: Gudmar extract; Gymnema silvestre, ext. Grades: 95%. CAS No. 90045-47-9. | |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. CAS No. 90045-47-9. Purity: 25% gymnemic acid. Product ID: CI-NAT-90045479. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gymnema Sylvestre Extract | Gymnema Sylvestre Extract. Applications: Used for health care products, dietary supplements, reduce hypoglycemic activity. Group: Others. Synonyms: Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult. CAS No. 1399-64-0. Purity: 25%, 75% Gymnemic Acid By UV. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Gymnema sylvestre ?Retz.? Schult. Gymnema Sylvestre Extract; 1399-64-0; Gymnema sylvestre ?Retz.? Schult.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-098. | |
| Gymnema Sylvestre Extract 75% | Gymnema Sylvestre Extract 75%. |  CA, FL & NJ |
| gymnemic acid | gymnemic acid. Grades: 95%. CAS No. 1399-64-0. | |
| Gymnemic acid | Gymnemic acid Inhibitor. Uses: Scientific use. Product Category: TN1718. CAS No. 122168-40-5. |  |
| Gymnemic acid I | Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122168-40-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2541. | |
| Gymnemic acid I | Gymnemic acid I. Alternative Names: (+)-Gymnemic Acid I. CAS No. 122168-40-5. Purity: >95.0%. Product ID: FFC-AR-122168405. Molecular formula: C43H66O14. Mole weight: 806.98. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gymnemic Acid I | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 122168-40-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Gymnestrogenin | Gymnestrogenin is a triterpenoid compound found in the Gymnema sylvestre. with dual LXRα/β antagonistic property. Alternative Names: (3S,4aS,5S,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-4a,9-bis(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-3,5,10-triol. Grades: >98%. CAS No. 19942-02-0. Molecular formula: C30H50O5. Mole weight: 490.725. | |
| Gymnestrogenin | Gymnestrogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19942-02-0. Pack Sizes: 5mg. Molecular Formula: C30H50O5, Molecular Weight: 490.73. US Biological Life Sciences. | Worldwide |
| Gymnin | Gymnin is a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill). Gymnin exerts antifungal activity against F.oxysporum and M.arachidicola, with an IC50 of 2 μM for the former fungus and 10 μM, respectively. It inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase. | |
| Gymnoside I | Gymnoside I (compound 1) is a glycosidoxybenzyl 2-isobutylmalic acid. Gymnoside I shows antiallergic activity in passive cutaneous allergic reaction (PCA) in mice. Gymnoside I can be used in research to research asthma, neurasthenia and chronic hepatitis[1]. Uses: Scientific research. Category: Natural products. CAS No. 899430-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N12127. | |
| Gym Rubber | Gym rubber is a high-density closed-cell foam with a medium feel and good resistance to oils and fuels. It is technically known as polyvinyl chloride/nitrile rubber/neoprene (PVC/NBR/CR) and is formally known as Ensolite IG2 by Armacell. |  |
| Gynostemma Extract | Gynostemma extract is prepared from the leaf of Gynostemma, a cucurbitaceous plant belongs to perennial grass nature lianas grows in the southeastern regions of China. Gynostemma pentaphyllum extract contains more than 80 different saponins, so is also known as southern ginseng. Gynostemma extract gypenoside is widely used as an anti aging supplement, or a tonic to treat bronchitis, strengthen the body, reduce fatigue, and reinforce overall health. Group: Others. Gynostemma Extract; Gynostemma Pentaphyllum Thunb. Cat No: EXTC-023. | |
| Gynostemma Pentaphyllum Extract (Ratio) | Gynostemma Pentaphyllum Extract (Ratio). Group: Others. Purity: 4:1~20:1. Gynostemma Pentaphyllum Extract (Ratio). Cat No: EXTW-037. | |
| Gypenoside I | Gypenoside I is an intricate phytochemical abundantly occurring in the plant known as Gynostemma Pentaphyllum. The multifaceted potential of Gypenoside I resides in its astonishingly promising capacity to potentially study a diverse array of maladies, which encompass the realms of cancer, diabetes, inflammation, as well as cardiovascular disorders. Alternative Names: (3β,12β)-20-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→6)-O-[β-D-glucopyranosyl-(1→2)]-β-D-glucopyranoside. CAS No. 85889-20-9. Molecular formula: C60H102O27. Mole weight: 1255.44. | |
| Gypenoside L | Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94987-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N8211. | |
| Gypenoside XLIX | Gypenoside XLIX. Group: Biochemicals. Grades: Plant Grade. CAS No. 94987-08-3. Pack Sizes: 20mg. Molecular Formula: C52H86O21, Molecular Weight: 1047.23. US Biological Life Sciences. | Worldwide |
| Gypenoside XLIX | Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation[1][2][3][4][5][6][7]. Uses: Scientific research. Category: SignalÂ… | |
| Gypenoside XLVI | Gypenosides are triterpenoid saponins isolated from Gynostemma pentaphyllum. Alternative Names: Gypenoside-XLVI; GypenosideXLVI. Grades: >98%. CAS No. 94705-70-1. Molecular formula: C48H82O19. Mole weight: 963.15. | |
| Gypenoside XLVI | Gypenoside XLVI. Group: Biochemicals. Grades: Plant Grade. CAS No. 94705-70-1. Pack Sizes: 10mg. Molecular Formula: C48H82O19, Molecular Weight: 963.16. US Biological Life Sciences. | Worldwide |
| Gypenoside XVII | Gypenoside XVII. Group: Biochemicals. Alternative Names: Gynosaponin S. Grades: Plant Grade. CAS No. 80321-69-3. Pack Sizes: 20mg. Molecular Formula: C48H82O18, Molecular Weight: 947.154. US Biological Life Sciences. | Worldwide |
| Gypsetin | It is produced by the strain of Nannizzia gypsea var. incurvata IFO 9228. It can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with IC50 of 18 μmol/L, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μmol/L. It also inhibits [14C] oleic acid from forming cholesterol esters with IC50 of 0.65 μmol/L. Alternative Names: Gypsetine; (-)-Gypsetin; 8a,16a-Dihydroxy-5a,13a-bis(1,1-dimethylallyl)-(1)-benzazolidine-(3''',2''':4'',5'')azolidino-(1'',2'':4',5')(1,4)perhydrodiazin-(1',2':1,5)azolidino-(2,3-b)-(1)-benzazolidine-7,15-dione; Pyrazino(1'',2'':1,5;4'',5'':1',5')dipyrrolo(2,3-b:2',3'-b')diindole-7,15(5H,7aH)-dione,5a,13a-bis(1,1-dimethyl-2-propenyl)-5a,8,8a,13,13a,15a,16,16a-octahydro-8a,16a-dihydroxy-, (5aalpha,7aalpha,8abeta,13abeta,15aalpha,16aalpha)-. CAS No. 155114-38-8. Molecular formula: C32H36N4O4. Mole weight: 540.66. | |
| Gypsogenic acid | Gypsogenic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 5143-5-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Gypsum Submicron | Gypsum Submicron. Molecular formula: CaSO4 2H2O. Purity: 99.9%. | |
| Gyrane | Gyrane. CAS No. 24237-00-1. VIGON Item # 503223. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Gyrophoric acid | Gyrophoric acid isolated from the herbs of Parmelia tinctorum Despr. Uses: Anti-tumor; anti-cancer; antibacterial; antimicrobial; anti-proliferative / cytotoxic effect. Alternative Names: triorsellinic acid; 4-[4-(2,4-dihydroxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoic acid. Grades: 0.98. CAS No. 548-89-0. Molecular formula: C24H20O10. Mole weight: 468.4. | |
| GYY4137 | GY4137 is a sustained-release H2S donor possessing vasodilatory, antihypertensive, and anti-inflammatory activities. GY4137 can inhibit cell growth, induce apoptosis, and cause cell cycle arrest by blocking the STAT3 pathway, demonstrating potent anticancer activity[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106740-09-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107632. | |
| GYY 4137 | Water-soluble, slow-releasing hydrogen sulfide (H2S) donor. Exhibits vasodilator and antihypertensive activity. Anti-inflammatory. Inhibits LPS-induced release of proinflammatory mediators (IL-1beta, IL-6, TNF-alpha, nitric oxide (NO) and PGE2) and increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-kappaB, ATF-2 and HSP27 dependent pathways. Causes stomatal opening and reduces nitric oxide accumulation in plants. Oxidative stress-induced cell death inhibitor. Shows novel anti-cancer effects in vitro and in vivo. Anti-thrombotic via p-selectin dependent mechanism. Group: Biochemicals. Grades: Highly Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H16NO2PS2 C4H9NO. US Biological Life Sciences. | Worldwide |
| GYY 4137 morpholine salt | GYY 4137 morpholine salt. Group: Biochemicals. Grades: Purified. CAS No. 106740-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Alternative Names: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt. Grades: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47. | |
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