A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Ground Calcium Carbonate for Industry | Ground Calcium Carbonate for Industry. Grade: 95%. CAS No. 72608-12-9. Molecular formula: CaCO3||||CaCO3||||CaCO3||||CaCO3||||CCaO3. Mole weight: 100.09. |  |
| Growth arrest-specific protein 7 (281-290) | Growth arrest-specific protein 7 (281-290) is a peptide derived from Growth arrest-specific protein 7. Growth arrest-specific protein 7 plays a role in promoting maturation and morphological differentiation of cerebellar neurons. Synonyms: GAS-7 (281-290). | |
| Growth Hormone | Growth hormone (GH, somatotropin) is a peptide hormone produced by the anterior pituitary gland. It is a single-chain polypeptide which consists of 191 amino acids. It is crucial in the regulation of growth, metabolism, and cell repair in humans. The secretion of growth hormone is stimulated by growth hormone-releasing hormone (GHRH) and inhibited by somatostatin. Growth hormone is released in a pulsatile manner with highest secretory peaks occurring during sleep and exercise. Applications: Gh is indicated for the treatment of gh deficiency in children and adults, to increase height, muscle mass and bone density. it is also indicated for treatment of turner syndrome, growth failure due to chronic kidney disease and prader-willi syndrome. gh is also used to treat muscle wasting that can follow severe burns and hiv infection. Category: Hormones. Synonyms: GH1; GH; GHN; GH-N; hGH-N; Pituitary Growth Hormone; Growth Hormone 1; Somatotropin. Product ID: 92801ES. Mole weight: Approximately 22 kDa. InChIKey: LEHSKCILCGLHIK-DLRMDCPISA-N. Appearance: Sterile filtered white lyophilized (freeze-dried) powder. |  |
| Growth Hormone, Human | Human growth hormone is a single-chain polypeptide hormone required for the growth of tissues. Synonyms: cb311; crecormon; humatrope; ly137998; norditropin; sj0011; OVINE SOMATOTROPIN; SOMATOTROPIN. Grade: 95%. CAS No. 12629-01-5. Molecular formula: C990H1529N263O299S7. Mole weight: 22124.12. | |
| GRP (14-27) (human, porcine, canine) | GRP (14-27) (human, porcine, canine). Synonyms: C-Terminal peptide bombesin; Gastrin releasing peptide (14-27); H-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2. CAS No. 81608-29-9. Molecular formula: C75H110N24O16S2. Mole weight: 1667.98. | |
| Grp75 Antibody [N3C14] | GRP 75,Grp75,Grp75/MOT. Group: Antibodies. Alternative Names: GRP 75,MOT, HSPA9. Pack Sizes: 20ul. Product ID: F0782. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| GRP78/BIP Antibody [J10G21] | BiP,BiP/GRP78,GRP78 BiP,GRP78/HSPA5,HSPA5,HSPA5/BiP/GRP78. Group: Antibodies. Alternative Names: BiP,BiP/GRP78,GRP78/HSPA5,HSPA5. Pack Sizes: 20ul. Product ID: F0221. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| GRP78/BIP Antibody [N15D19] | BiP,BiP/GRP78,GRP78 BiP,GRP78/HSPA5,HSPA5,HSPA5/BiP/GRP78. Group: Antibodies. Alternative Names: BiP,BiP/GRP78,GRP78/HSPA5,HSPA5. Pack Sizes: 20uL. Product ID: F2702. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Grp94 Inhibitor-1 | Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2234897-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112910. |  |
| Grp94 Inhibitor-1 | Grp94 Inhibitor-1 is a potent and selective inhibitor of Grp94 (IC50 = 2 nM), and over 1000-fold selectivity to Grp94 against Hsp90α. Synonyms: [1,1'-Biphenyl]-3-carboxamide, 4-[(trans-4-hydroxycyclohexyl)amino]-4'-(1-methylethyl)-; 4-[(trans-4-Hydroxycyclohexyl)amino]-4'-isopropyl-3-biphenylcarboxamide; rel-4-(((1R,4R)-4-hydroxycyclohexyl)amino)-4'-isopropyl-[1,1'-biphenyl]-3-carboxamide. Grade: ≥98%. CAS No. 2234897-35-7. Molecular formula: C22H28N2O2. Mole weight: 352.47. | |
| GRPP (human) | GRPP (human) is a synthetic analogue of a cleavage product resulting from proglucagon processing in pancreatic α- and intestinal L-cells. Synonyms: Preproglucagon (21-50) (human); H-Arg-Ser-Leu-Gln-Asp-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Ser-Ala-Ser-Gln-Ala-Asp-Pro-Leu-Ser-Asp-Pro-Asp-Gln-Met-Asn-Glu-Asp-OH; glicentin-related polypeptide (human); L-arginyl-L-seryl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-seryl-L-arginyl-L-seryl-L-phenylalanyl-L-seryl-L-alanyl-L-seryl-L-glutaminyl-L-alanyl-L-alpha-aspartyl-L-prolyl-L-leucyl-L-seryl-L-alpha-aspartyl-L-prolyl-L-alpha-aspartyl-L-glutaminyl-L-methionyl-L-asparagyl-L-alpha-glutamyl-L-aspartic acid. Grade: ≥95%. CAS No. 1132745-52-8. Molecular formula: C136H215N41O58S. Mole weight: 3384.47. | |
| GRP (porcine) | GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to activate GABAergic interneurons in the amygdala resulting in an increase in GABA release and fear suppression in mice in vivo. Synonyms: Gastrin Releasing Peptide porcine. CAS No. 74815-57-9. Molecular formula: C126H198N38O31S2. Mole weight: 2805.31. | |
| GRPSp | GRPSp was found in the mud crab Scylla paramamosain. It is active against Gram-positive A. viridans, M. Luteus, (MIC=6-25 μg/ml). Grade: >97% by HPLC. | |
| Grubbs Catalyst, 2nd gen | 100mg Pack Size. Group: Catalysts. Formula: C46H65Cl2N2PRu. CAS No. 246047-72-3. Prepack ID 60505776-100mg. Molecular Weight 848.97. See USA prepack pricing. |  |
| Grubbs Catalyst, 2nd Generation | Grubbs Catalyst, 2nd Generation is a ruthenium-based olefin metathesis catalyst. Group: Biochemicals. Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 250mg, 500 mg. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. |  Worldwide |
| Grubbs catalyst I | Grubbs catalyst I. Group: Biochemicals. Alternative Names: Bis- (tri cyclohexylphosphino) -benzylide ne ruthenium dichloride. Grades: Highly Purified. CAS No. 172222-30-9. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C44H74Cl2P2Ru. US Biological Life Sciences. | Worldwide |
| Grubbs catalyst II | Grubbs catalyst II. Group: Biochemicals. Alternative Names: [1, 3-Bis- (2, 4, 6-tri methyl phenyl) -2-imidazolidinylide ne ] -dichloro- (phenyl methyl ene ) (tri cyclohexylphosphine) -ruthenium. Grades: Highly Purified. CAS No. 246047-72-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C46H65Cl2N2PRu. US Biological Life Sciences. | Worldwide |
| Gruticibart | Gruticibart is an anti-F11 human IgG4 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: AB023; Xisomab 3G3; MAB 14E11. CAS No. 2704554-77-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990743. | |
| GS143 | GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup-presses NF-κB acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 916232-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110261. | |
| GS 143 | GS 143 is a β-TrCP1 ligase inhibitor. GS 143 exhibits inhibitory effects on IκBα ubiquitination (IC50 = 5.2 μM), LPS-induced expression of inflammatory cytokines in human myelomonocytic cells, antigen-induced NFκB expression, inflammation and mucus production in airways of OVA-sensitized mice. Synonyms: GS-143; GS 143; GS143; 4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid. Grade: ≥98% by HPLC. CAS No. 916232-21-8. Molecular formula: C28H19FN2O4. Mole weight: 466.46. | |
| GS-2278 | GS-2278 is an LPAR1 (lysophosphatidic acid receptor 1) antagonist with potential for research in idiopathic pulmonary fibrosis (IPF)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750508-72-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159983. | |
| GS-283 | GS-283, an isoquinolin derivative, has been found to be histamine receptor and muscarinic receptor blocker. Synonyms: GS 283; GS-283; GS283; 6,7-Isoquinolinediol, 3,4-dihydro-1-((4-methoxyphenyl)methyl)-; 7-hydroxy-1-[(4-methoxyphenyl)methyl]-3,4-dihydro-2H-isoquinolin-6-one. Grade: 98%. CAS No. 149440-36-8. Molecular formula: C17H17NO3. Mole weight: 283.33. | |
| GS 389 | GS 389 is a novel tetrahydroisoquinoline analog which significantly increased cGMP levels in the rat aorta and inhibited cGMP phosphodiesterase from the rabbit brain. Uses: A novel tetrahydroisoquinoline analog. Synonyms: GS 389; GS-389; GS389. 6,7-dimethoxy-1-[(4-methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline. Grade: ≥98%. CAS No. 41498-37-7. Molecular formula: C19H23NO3. Mole weight: 313.39. | |
| GS 39783 | GS 39783. Group: Biochemicals. Alternative Names: N4,N6-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine. Grades: Highly Purified. CAS No. 39069-52-8. Pack Sizes: 10mg. Molecular Formula: C15H23N5O2S, Molecular Weight: 337.44. US Biological Life Sciences. | Worldwide |
| GS 39783 | GS 39783 is an allosteric positive modulator of GABAB receptors, decreases cocaine self-administration, blocks the rewarding properties of nicotine and produces anxiolytic-like activity without the side effects associated with baclofen or benzodiazepines. Uses: Positive allosteric modulator of gabab receptor function. Synonyms: GS39783; GS-39783; GS 39783; N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine; 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine. Grade: ≥98%. CAS No. 39069-52-8. Molecular formula: C15H23N5O2S. Mole weight: 337.44. | |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Synonyms: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile; Remdesivir metabolite GS-441524; GS 441524; GS441524; (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. Grade: 97%. CAS No. 1191237-69-0. Molecular formula: C12H13N5O4. Mole weight: 291.26. | |
| GS-441524 | GS-441524 is a pyrrolotriazine, a nitrile, a C-nucleoside, and an aromatic amine. It is a (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile which is 2-substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group. It is an active metabolite of remdesivir. It is a broad-spectrum inhibitor of replication of RNA viruses, with inhibitory activity being confirmed for HCV, parainfluenza and SARS-CoV. It has the drug targets of a drug metabolite, an antiviral agent and an anticoronaviral agent. Applications: Gs-441524 is a potent antiviral nucleoside analogue that has transformed the treatment of previously fatal viral diseases, most notably in feline medicine. it is the parent molecule and primary metabolite of the well-known human antiviral remdesivir. Category: Intermediates. CAS No. 1191237-69-0. Product ID: INT1191237690. Molecular formula: C12H13N5O4. Mole weight: 291.26. EINECS: 857-885-9. InChIKey: BRDWIEOJOWJCLU-LTGWCKQJSA-N. Appearance: White to off-white solid. | |
| GS-441524 | GS-441524 is a potent, orally active and CNS-penetrant viral RNA-dependent RNA polymerase inhibitor. GS-441524 competes with natural nucleosides to block viral RNA transcription as an alternative substrate and RNA chain terminator. GS-441524 inhibits the replication of feline infectious peritonitis virus, African swine fever virus, and severe acute respiratory syndrome coronavirus 2. GS-441524 reduces viral RNA levels in cats. GS-441524 can be used in research related to feline infectious peritonitis, African swine fever, and coronavirus disease 2019 (COVID-19)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1191237-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-103586. | |
| GS-443902 | GS-443902 is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Uses: Antiviral agents. Synonyms: GS-441524 triphosphate; Remdesivir metabolite; RDV-TP. Grade: 99.87%. CAS No. 1355149-45-9. Molecular formula: C12H16N5O13P3. Mole weight: 531.20. | |
| GS-443902 trisodium | GS-443902 trisodium is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Synonyms: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. Grade: 99%. CAS No. 1355050-21-3. Molecular formula: C12H12N5Na4O13P3. Mole weight: 619.13. | |
| GS-443902 trisodium | GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. CAS No. 1355050-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126303C. | |
| GS-444217 | GS-444217 is an orally available and ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with IC50 of 2.87 nM. Synonyms: ASK1-IN-1. CAS No. 1262041-49-5. Molecular formula: C23H21N7O. Mole weight: 411.46. | |
| GS-444217 | GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1262041-49-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100844. | |
| GS-566500 | GS-566500 is a compound of Sofosbuvir metabolite. Category: Active pharmaceutical ingredients. CAS No. 1233335-78-8. Product ID: API1233335788. Molecular formula: C13H19FN3O9P. Mole weight: 411.27. | |
| GS 6201 | GS 6201. Group: Biochemicals. Grades: Purified. CAS No. 752222-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GS 6201 | GS 6201 is a selective A2B antagonist. Synonyms: CVT6883; CVT 6883; CVT-6883; GS6201; GS-6201; GS 6201; 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione. CAS No. 752222-83-6. Molecular formula: C21H21F3N6O2. Mole weight: 446.43. | |
| GS-621763 | GS-621763 is an orally bioavailable prodrug of GS-441524. The nucleoside metabolite of remdesivir, GS-441524 displays potent anti-SARS-CoV-2 efficacy, and is being evaluated in clinical as an oral antiviral therapeutic for COVID-19. Synonyms: GS-441524 prodrug. Grade: 98%. CAS No. 2647442-13-3. Molecular formula: C24H31N5O7. Mole weight: 501.53. | |
| GS-621763 | GS-621763 is an orally available precursor to GS-441524 that exhibits anti-SARS-CoV-2 viral activity in mice. GS-621763 reduces viral load to undetectable levels in ferrets infected with SARS-CoV-2[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2647442-13-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145119. | |
| GS-704277 | GS-704277 is an alanine metabolite of Remdesivir (HY-104077). GS-704277 is further hydrolyzed to GA-441524 (HY-103586) with antiviral activity. Remdesivir, a nucleoside analogue with effective antiviral activity, is highly effective in the control of SARS-CoV-2 (COVID-19) infection[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1911579-04-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-136303. | |
| GS-7340 fumarate | Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grade: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 59 | |
| GS-9219 | GS-9219 is a prodrug of the acyclic nucleoside phosphonate analogue 9-(2-phosphonylmethoxyethyl)guanine (PMEG) with potential antineoplastic activity. Formulated to selectively accumulate in lymphocytes, nucleotide analogue GS 9219 is converted to its active metabolite, PMEG diphosphate (PMEGpp), via enzymatic hydrolysis, deamination, and phosphorylation; subsequently, PMEGpp is incorporated into nascent DNA chains by DNA polymerases, which may result in the termination of DNA synthesis, S-phase cell cycle arrest, and the induction of apoptosis in susceptible lymphoma cell populations. Synonyms: GS 9219; GS9219. CAS No. 859209-74-8. Molecular formula: C21H35N8O6P. Mole weight: 526.53. | |
| GS 9620 | GS 9620 is a potent and oral agonist of TLR7. Uses: Antiviral agents. Synonyms: 4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one; GS-9620; GS9620; Vesatolimod. Grade: 99.90%. CAS No. 1228585-88-3. Molecular formula: C22H30N6O2. Mole weight: 410.51. | |
| GS9667 | GS9667 is a new selective, partial agonist of the A(1) adenosine receptor (AR). It may be an effective therapy for Type 2 diabetes and dyslipidemia via lowering of free fatty acids (FFA). It was developed by Gilead and was in clinic phase 1 trials without progress. Uses: Gs966 may be an effective therapy for type 2 diabetes and dyslipidemia via lowering of free fatty acids (ffa). Synonyms: GS-9667; GS 9667; CVT-3619; CVT 3619; CVT3619. Grade: 98%. CAS No. 618380-90-8. Molecular formula: C21H24FN5O4S. Mole weight: 461.51. | |
| GS967 | GS967, also known as GS-458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD- and DAD-mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Synonyms: GS967; GS-967; GS 967; GS458967; GS 458967; GS-458967. Grade: 95%. CAS No. 1262618-39-2. Molecular formula: C14H7F6N3O. Mole weight: 347.22. | |
| GS967 | GS967 (GS-458967) is a potent, and selective inhibitor of cardiac late sodium current (late INa ) with IC50 values of 0.13 and 0.21 μM for ventricular myocytes and isolated hearts, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1262618-39-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 250 mg; 500 mg. Product ID: HY-12593. | |
| GS-9822 | GS-9822 is one of novel non-catalytic site integrase inhibitors (NCINIs), which is a potential class of antiretroviral (ARV) agents. GS-9822 exhibits a potent effect against the T174I mutant (EC50: 3.0 ± 0.9 nM) and IN polymorphic variants (fold shift: 0.4 to 1.3). Studies showed that it has excellent pharmacokinetic properties and metabolic stability. Uses: Antiretroviral (arv) agent. Synonyms: 2219362-41-9; GS-9822; (S)-2-(tert-Butoxy)-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-3-(1-(oxetan-3-yl)piperidin-4-yl)-1H-indazol-5-yl)benzo[d]thiazol-6-yl)acetic acid; SCHEMBL20030699; DA-63908; HY-122229; CS-0082907; (2S)-2-tert-butoxy-2-[7-(4-chlorophenyl)-5-methyl-2-[1-methyl-3-[1-(oxetan-3-yl)-4-piperidyl]indazol-5-yl]-1,3-benzothiazol-6-yl]acetic acid. CAS No. 2219362-41-9. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| GSA 10 | GSA 10. Group: Biochemicals. Grades: Purified. CAS No. 300833-95-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GSA 10 | GSA 10 is a quinolinecarboxamide derivative that acts as a Smoothened/Smo receptor agonist (EC50 = 1.2 μM). GSA 10 can promote differentiation of multipotent mesenchymal progenitor cells into osteoblasts. Uses: Smoothened (smo) receptor agonist. Synonyms: GSA-10; propyl 4-[(1-hexyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]benzoate. Grade: >98%. CAS No. 300833-95-8. Molecular formula: C26H30N2O5. Mole weight: 450.53. | |
| GSA-10 | GSA-10 is a potent smooth (Smo) receptor agonist. GSA-10 is a potent osteogenic molecule. GSA-10 can mediate Hedgehog (Hh) signaling. GSA-10 can be used in regenerative medicine for cancer disease and in the study of fat development[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 300833-95-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12317. | |
| Gsa I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 70°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CCCAG↑C G↓GGTCG. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Geobacillus stearothermophilus Y. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1115RE. |  |
| GS-CA-1 | GS-CA-1 is a novel HIV capsid inhibitor developed by Gilead, which is a promisingly long-acting antiretroviral (ARV) agent. The preclinical study showed that GS-CA-1 could inhibit HIV-1 replication in human peripheral blood mononuclear cells (PBMCs) (EC50 = 140 pM). Uses: Long-acting antiretroviral (arv) agent. Synonyms: GS CA 1. Grade: 99.94%. CAS No. 2189684-45-3. Molecular formula: C41H36ClF8N7O5S2. Mole weight: 958.34. | |
| GSDMD Antibody [B5P20] | Gasdermin D,GSDMD,GSDMDC1. Group: Antibodies. Alternative Names: DF 5L; DF5L; DFNA 5L; DFNA5L; FKSG 10; FKSG10; FLJ12150; GSDMDC1; GSDMD. Pack Sizes: 20uL. Product ID: F1568. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| GSH-CdTe, | GSH-CdTe. |  |
| GSH (Glutathione) | GSH (Glutathione). CAS No. 70-18-8. Product ID: CI-HC-0352. Molecular formula: C10H17N3O6S. Mole weight: 307.33 g/mol. ECNumber: 200-725-4. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| GSH (L-Glutathione reduced) | GSH (Glutathione) acts as an antioxidant, a free radical scavenger and a detoxifying agent. It is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue. Group: Inhibitors. Alternative Names: Isethion, Glutathion, Tathion, L-Glutathione reduced, γ-L-Glutamyl-L-cysteinyl-glycine. CAS No. 70-18-8. Pack Sizes: 100mg. Product ID: S4606. Formula: C10H17N3O6S. Smiles: C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| GSHtracer | GSHtracer is a ratiometric probe for measuring of GSH levels. GSHtracer exhibits Ex/Em from 520/580 nm to 430/510 nm (upon GSH binding) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1479071-34-5. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131013. | |
| GSI-136 | GSI-136 is an amyloid precursor protein secretase inhibitor. Uses: Γ-secretase inhibitor. Synonyms: GSI-136; GSI 136; GSI136. (S)-5-chloro-N-(3-ethyl-1-hydroxypentan-2-yl)thiophene-2-sulfonamide. Grade: ≥98%. CAS No. 443989-01-3. Molecular formula: C11H18ClNO3S2. Mole weight: 311.83. | |
| GSK046 | GSK046 is a potent, selective and orally active inhibitor of BET with immunomodulatory activity. GSK046 reduces the recruitment of BET proteins to interferon (IFN) target genes following IFN-γ stimulation. Synonyms: iBET-BD2; GSK 046; GSK-046. CAS No. 2474876-09-8. Molecular formula: C23H27FN2O4. Mole weight: 414.47. | |
| GSK046 | GSK046 (iBET-BD2), a chemical probe, is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. GSK046 has immunomodulatory activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: iBET-BD2. CAS No. 2474876-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136571. | |
| GSK0660 | GSK0660 is a potent PPARβ antagonist with an IC50 of 155 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1014691-61-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12377. | |
| GSK0660 | GSK0660 is a selective PPARδ antagonist. GSK0660 blocks the effect of TNFα on the expressions of cytokines involved in leukocyte recruitment, including CCL8, CCL17, and CXCL10, and it may block TNFα-induced retinal leukostasis. Synonyms: GSK0660; GSK-0660; GSK 0660. Grade: 96%. CAS No. 1014691-61-2. Molecular formula: C19H18N2O5S2. Mole weight: 418.48. | |
| GSK 0660 | GSK 0660. Group: Biochemicals. Grades: Purified. CAS No. 1014691-61-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GSK097 | GSK097, a potent and selective inhibitor of the second bromodomain (BD2) of the bromodomain and extra-terminal domain (BET) proteins, shows 2000-fold selectivity for BD2 over BD1 (BRD4 data) with >1 mg/mL solubility in FaSSIF media. Synonyms: 2,4-Pyridinedicarboxamide, 6-[(S)-hydroxyphenylmethyl]-N2-methyl-N4-[(1S,2S)-2-methylcyclopropyl]-. CAS No. 2159137-02-5. Molecular formula: C19H21N3O3. Mole weight: 339.39. | |
| GSK-1014802 hydrochloride | GSK-1014802 hydrochloride is the hydrochloride form of GSK-1014802, which is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. It acts as a selective, small-molecule, state-dependent Nav1.7 voltage-gated sodium channel blocker. It received orphan-drug designation from the US Food and Drug Administration in July 2013. It was developed by Convergence Pharmaceuticals. It is currently in phase II studies in bipolar depression. Uses: Gsk-1014802 hydrochloride is a novel analgesic for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia. it received orphan-drug designation from the us food and drug administration in july 2013. Synonyms: GSK-1014802 hydrochloride; GSK 1014802 hydrochloride; GSK1014802 hydrochloride; (2S,5R)-5-(4-((2-Fluorobenzyl)oxy)phenyl)pyrrolidine-2-carboxamide hydrochloride; (5R)-5-(4-{[(2-fluorophenyl)methyl]oxy}phenyl)-L-prolinamide hydrochlorideCNV1014802 hydrochloride; CNV-1014802 hydrochloride; Raxatrigine hydrochloride. Grade: >98%. CAS No. 934240-31-0. Molecular formula: C18H20ClFN2O2. Mole weight: 350.82. | |
| GSK1016790A | GSK1016790A is a novel and potent transient receptor potential vanilloid 4 (TRPV4) agonist. It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone. It elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells with EC50 values of 18 and 2.1 nM, respectively. It also evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM, which is 300 fold more potent than 4a-PDD. It was developed by GlaxoSmithKline. Uses: Gsk1016790a regulats urinary bladder activity and endothelial control of vascular tone. Synonyms: GSK1016790A; GSK-1016790A; GSK 1016790A. N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide. Grade: >98 %. CAS No. 942206-85-1. Molecular formula: C28H32Cl2N4O6S2. Mole weight: 655.61. | |
| GSK1016790A | GSK1016790A is a novel and potent TRPV4 channel agonist. The TRPV4 (transient receptor potential vanilloid 4) member of the TRP superfamily has been implicated in numerous physiological processes. GSK1016790A elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300 fold more potent than 4a-PDD. Applications: A novel and potent trpv4 channel agonist. Group: Coenzymes. Synonyms: (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide. CAS No. 942206-85-1. Purity: ≥98%. Mole weight: 655.61. Form: Solid. (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide; GSK1016790A; 942206-85-1. Cat No: COEC-115. | |
| GSK1016790A | GSK1016790A is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel agonist. GSK1016790A can elicit Ca2+ influx and elevate intracellular Ca2+ in HEK cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 942206-85-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19608. | |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 958852-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12036. | |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Synonyms: GSK-1059615; GSK 1059615; GSK1059615. Grade: >98%. CAS No. 958852-01-2. Molecular formula: C18H11N3O2S. Mole weight: 333.36. | |
| GSK1059865 | GSK1059865 is a potent orexin 1 receptor antagonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 1191044-58-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101534. | |
Our database is helping our users find suppliers everyday.
