A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAX69; Anti-Human MIF Recombinant Antibody. CAS No. 1430205-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99262.
Imaradenant
AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist. AZD4635 binds to human A2AR with a Ki of 1.7 nM and shows >30-fold selectivity over other adenosine receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HTL1071; AZD4635. CAS No. 1321514-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101980.
Imatinib
Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15463.
Imatinib
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Synonyms: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. Grade: >98%. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.60.
Imatinib-[d3]
Imatinib-[d3] is the labelled analogue of Imatinib. Imatinib can be used for the treatment of chronic myelogenous leukemia and acute lymphocytic leukemia. Synonyms: Imatinib D3; Genfatinib-d3; 4-[[4-(methyl-d3)-1-piperazinyl]methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grade: 95% by HPLC; 99% atom D. CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.62.
Imatinib-d4
Imatinib-d4 (STI571-d4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571 d4; CGP-57148B d4. CAS No. 1134803-16-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15463S1.
Imatinib-[d4]
Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Synonyms: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4; Imatinib D4. Grade: ≥98% (HPLC). CAS No. 1134803-16-9. Molecular formula: C29H27D4N7O. Mole weight: 497.64.
Imatinib-d8
Imatinib-d8 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571-d8; CGP-57148B-d8. CAS No. 1092942-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-15463S.
Imatinib-d8
Imatinib-d8 is a deuterated tyrosine kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092942-82-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C29H23D8N7O. US Biological Life Sciences.
Worldwide
Imatinib-[d8]
Imatinib-[d8] is the labelled analogue of Imatinib, a treatment of chronic myeloid leukemia. Synonyms: Imatinib D8; 4-[(4-Methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; Genfatinib-d8. Grade: 95% by HPLC; 95% atom D. CAS No. 1092942-82-9. Molecular formula: C29H23D8N7O. Mole weight: 501.65.
A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Biochemicals. Alternative Names: Imatinib-d8 Methanesulfonate, STI-571-d8, CGP-57148B-d8, Glivec-d8. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Imatinib Dimer Impurity
Imatinib Dimer Impurity. Uses: For analytical and research use. CAS No. 1365802-18-1. Molecular formula: C52H48N12O2. Mole weight: 873.04. Catalog: APB1365802181.
Imatinib EP Impurity B HCl
Imatinib EP Impurity B HCl. Uses: For analytical and research use. CAS No. 581076-67-7. Molecular formula: C21H29ClN6O. Mole weight: 416.95. Catalog: APB581076677.
Imatinib EP Impurity C-D8
Imatinib EP Impurity C-D8. Uses: For analytical and research use. CAS No. 1185103-28-9. Molecular formula: C28H21D8N7O. Mole weight: 487.64. Catalog: APB1185103289.
Imatinib EP Impurity D
Imatinib EP Impurity D. Uses: For analytical and research use. CAS No. 1821122-73-9. Molecular formula: C53H51N12O2. Mole weight: 888.07. Catalog: APB1821122739.
Imatinib EP Impurity H
Imatinib EP Impurity H. Uses: For analytical and research use. CAS No. 350-03-8. Molecular formula: C7H7NO. Mole weight: 121.14. Catalog: APB350038.
Imatinib, Free base
An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100ug, 1g. US Biological Life Sciences.
Worldwide
Imatinib Imidazole Impurity
Imatinib Imidazole Impurity. Uses: For analytical and research use. CAS No. 1256080-10-0. Molecular formula: C32H31N9O2. Mole weight: 573.66. Catalog: APB1256080100.
Imatinib Impurity 11
Imatinib Impurity 11. Uses: For analytical and research use. CAS No. 796738-71-1. Molecular formula: C16H13N5O2. Mole weight: 307.31. Catalog: APB796738711.
Imatinib Impurity 12
Imatinib Impurity 12. Uses: For analytical and research use. CAS No. 112696-91-0. Molecular formula: C16H15N5. Mole weight: 277.33. Catalog: APB112696910.
Imatinib Impurity 16
Imatinib Impurity 16. Uses: For analytical and research use. CAS No. 152460-09-8. Molecular formula: C16H13N5O2. Mole weight: 307.31. Catalog: APB152460098.
Imatinib Impurity 17
Imatinib Impurity 17. Uses: For analytical and research use. CAS No. 1802325-93-4. Molecular formula: C20H22N2O4. Mole weight: 354.41. Catalog: APB1802325934.
Imatinib Impurity 18
Imatinib Impurity 18. Uses: For analytical and research use. CAS No. 404844-11-7. Molecular formula: C24H20ClN5O. Mole weight: 429.91. Catalog: APB404844117.
Imatinib Impurity 2
Imatinib Impurity 2. Uses: For analytical and research use. CAS No. 1384131-91-2. Molecular formula: C7H11NO. Mole weight: 125.17. Catalog: APB1384131912.
Imatinib Impurity 26
Imatinib Impurity 26. Uses: For analytical and research use. CAS No. 74231-65-5. Molecular formula: C8H5Cl2N. Mole weight: 186.04. Catalog: APB74231655.
Imatinib Impurity 27
Imatinib Impurity 27. Uses: For analytical and research use. CAS No. 67013-55-2. Molecular formula: C8H5Br2N. Mole weight: 274.94. Catalog: APB67013552.
Imatinib Impurity 29
Imatinib Impurity 29. Uses: For analytical and research use. CAS No. 21900-30-1. Molecular formula: C8H6Cl2O. Mole weight: 189.04. Catalog: APB21900301.
Imatinib Impurity 3
Imatinib Impurity 3. Uses: For analytical and research use. CAS No. 152459-96-6. Molecular formula: C24H21N5O. Mole weight: 395.47. Catalog: APB152459966.
Imatinib Impurity 30
Imatinib Impurity 30. Uses: For analytical and research use. CAS No. 36747-64-5. Molecular formula: C8H5Cl3O. Mole weight: 223.48. Catalog: APB36747645.
Imatinib Impurity 31
Imatinib Impurity 31. Uses: For analytical and research use. CAS No. 1356565-47-3. Molecular formula: C17H17N7. Mole weight: 319.37. Catalog: APB1356565473.
Imatinib Impurity 32
Imatinib Impurity 32. Uses: For analytical and research use. CAS No. 16156-50-6. Molecular formula: C7H16O3S. Mole weight: 180.26. Catalog: APB16156506.
Imatinib impurity 35 (Hydrochloride)
Imatinib impurity 35 (Hydrochloride). Uses: For analytical and research use. Alternative Names: 4-((4-methylpiperazin-1-yl)methyl)benzoic acid hydrochloride. Molecular formula: C13H18N2O2·HCl. Mole weight: 361.31. Catalog: APB01554.
Imatinib impurity 36
Imatinib impurity 36. Uses: For analytical and research use. Alternative Names: 1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1,4-dioxide. CAS No. 571186-93-1. Molecular formula: C29H31N7O3. Mole weight: 525.6. Catalog: APB571186931.
Imatinib Impurity 36
Imatinib Impurity 36. Uses: For analytical and research use. CAS No. 106261-48-7. Molecular formula: C13H18N2O2. Mole weight: 234.3. Catalog: APB106261487.
Imatinib Impurity 37
Imatinib Impurity 37. Uses: For analytical and research use. CAS No. 1912-32-9. Molecular formula: C5H12O3S. Mole weight: 152.21. Catalog: APB1912329.
Imatinib Impurity 38
Imatinib Impurity 38. Uses: For analytical and research use. CAS No. 5973-83-1. Molecular formula: C7H8N2O. Mole weight: 136.15. Catalog: APB5973831.
Imatinib Impurity 4
Imatinib Impurity 4. Uses: For analytical and research use. CAS No. 942514-62-7. Molecular formula: C30H33N7O. Mole weight: 507.64. Catalog: APB942514627.
Imatinib Impurity 40
Imatinib Impurity 40. Uses: For analytical and research use. CAS No. 581076-66-6. Molecular formula: C24H19Cl2N5O. Mole weight: 464.35. Catalog: APB581076666.
Imatinib Impurity 41
Imatinib Impurity 41. Uses: For analytical and research use. CAS No. 870459-88-4. Molecular formula: C8H10N4O2. Mole weight: 194.19. Catalog: APB870459884.
Imatinib Impurity 5
Imatinib Impurity 5. Uses: For analytical and research use. CAS No. 1032314-73-0. Molecular formula: C17H17N5. Mole weight: 291.36. Catalog: APB1032314730.
Imatinib Impurity 53
Imatinib Impurity 53. Uses: For analytical and research use. CAS No. 1356565-46-2. Molecular formula: C42H47N9O2. Mole weight: 709.9. Catalog: APB1356565462.
Imatinib Impurity 59
Imatinib Impurity 59. Uses: For analytical and research use. CAS No. 796738-72-2. Molecular formula: C8H10N4O2. Mole weight: 194.19. Catalog: APB796738722.
Imatinib Impurity 6
Imatinib Impurity 6. Uses: For analytical and research use. CAS No. 1349250-06-1. Molecular formula: C29H31N7O. Mole weight: 493.61. Catalog: APB1349250061.
Imatinib Impurity 62
Imatinib Impurity 62. Uses: For analytical and research use. CAS No. 314268-40-1. Molecular formula: C14H20N2O2. Mole weight: 248.33. Catalog: APB314268401.
Imatinib Impurity 67
Imatinib Impurity 67. Uses: For analytical and research use. CAS No. 7115-89-1. Molecular formula: C8H7BrO2. Mole weight: 215.05. Catalog: APB7115891.
Imatinib Impurity 7
Imatinib Impurity 7. Uses: For analytical and research use. CAS No. 581076-64-4. Molecular formula: C8H12N4. Mole weight: 164.21. Catalog: APB581076644.
Imatinib Impurity 8
Imatinib Impurity 8. Uses: For analytical and research use. CAS No. 1407229-73-5. Molecular formula: C21H25N2O4+. Mole weight: 369.44. Catalog: APB1407229735.
Imatinib impurity A
Imatinib impurity A. Uses: For analytical and research use. Alternative Names: N-(3-guanidino-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. CAS No. 581076-65-5. Molecular formula: C21H28N6O. Mole weight: 380.49. Catalog: APB581076655.
Imatinib impurity B
Imatinib impurity B. Uses: For analytical and research use. Alternative Names: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide. CAS No. 404844-02-6. Molecular formula: C28H29N7O. Mole weight: 479.58. Catalog: APB404844026.
Imatinib impurity C
Imatinib impurity C. Uses: For analytical and research use. Alternative Names: 1-methyl-1,4-bis(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium. Molecular formula: C53H51N12O2+. Mole weight: 888.05. Catalog: APB02181.
Imatinib impurity D
Imatinib impurity D. Uses: For analytical and research use. Alternative Names: 6-methyl-N1-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine. CAS No. 152460-10-1. Molecular formula: C16H15N5. Mole weight: 277.32. Catalog: APB152460101.
Imatinib impurity I
Imatinib impurity I. Uses: For analytical and research use. Alternative Names: 1-methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1-oxide. CAS No. 571186-91-9. Molecular formula: C29H31N7O2. Mole weight: 509.6. Catalog: APB571186919.
Imatinib impurity J
Imatinib impurity J. Uses: For analytical and research use. Alternative Names: (E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one. CAS No. 123367-26-0. Molecular formula: C10H12N2O. Mole weight: 176.22. Catalog: APB123367260.
Imatinib Impurity K
Imatinib Impurity K. Uses: For analytical and research use. CAS No. 2410195-20-7. Molecular formula: C17H15N5O. Mole weight: 305.34. Catalog: APB2410195207.
Imatinib Impurity X
Imatinib Impurity X. Uses: For analytical and research use. CAS No. 75415-01-9. Molecular formula: C10H12N2O. Mole weight: 176.22. Catalog: APB75415019.
Imatinib mesylate
Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Synonyms: CGP-57148B; CGP 57148B; CGP57148B; Gleevec, Imatinib. Grade: >98%. CAS No. 220127-57-1. Molecular formula: C29H31N7O.CH4SO3. Mole weight: 589.71.
Imatinib mesylate
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H31N7O · CH4O3S. CAS No. 220127-57-1. Prepack ID 60579435-100mg. Molecular Weight 589.71. See USA prepack pricing.
Imatinib Mesylate
Imatinib Mesylate (STI571 Mesylate) is an orally active tyrosine kinases inhibitor that inhibits c-Kit, Bcr-Abl, and PDGFR (IC50=100 nM) tyrosine kinases. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571 Mesylate; CGP-57148B Mesylate. CAS No. 220127-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-50946.
Imatinib Mesylate
Imatinib mesylate is a c-Abl, PDGFR, and c-kit inhibitor that halts chronic myelogenous leukemia related growth. Category: Active pharmaceutical ingredients. CAS No. 220127-57-1. Product ID: API220127571. Molecular formula: C29H31N7O CH3SO3H. Mole weight: 589.71. Appearance: Crystalline powder.
Imatinib Meta-methyl-piperazine Impurity
Imatinib impurity. Group: Biochemicals. Alternative Names: 3- [ (4-Methyl-1-piperazinyl) methyl] -N- [4-methyl-3- [ (4-pyridinyl) -2-pyrimidinylamino] phenyl] benzamide. Grades: Highly Purified. CAS No. 1246819-59-9. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Imatinib, Methanesulfonate Salt (STI-571, CGP-57148B)
A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Imatinib inhibits bcr-abl tyrosine kinase activity, upon which some types of tumor cells depend for growth. Imatinib acts by binding to the ATP binding site of bcr-abl and competitively inhibiting its tyrosine kinase activity. Imatinib is selective for bcr-abl, but it also targets several other kinases (c-kit and PDGF-R). (1). Group: Biochemicals. Alternative Names: 4- [ (4-Methyl-1-piperazinyl) methyl] -N- [4-methyl-3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] phenyl] benzamide Methanesulfonate; CGP 57148B; Imatinib Mesilate; Imatinib Methanesulfonate; Imatinib Mesylate; STI 571; Bcr-abl Inhibitor IV; Abl Inhibitor V, PDGFR Tyrosine Kinase Inhibitor XXIV, c-Kit Inhibitor IV. Grades: Highly Purified. CAS No. 220127-57-1. Pack Sizes: 25mg, 1g, 5g, 10g. US Biological Life Sciences.
Imatinib (Piperidine)-4-oxide is an impurity of Imatinib (Gleevec). Imatinib impurity D. Group: Biochemicals. Alternative Names: 4- [ (4-Methyl-4-oxido-1-piperazinyl) methyl] -N- [4-methyl-3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] phenyl] benzamide; CGP 71422. Grades: Highly Purified. CAS No. 571186-91-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Imatinib (piperidine)-N-oxide
Imatinib (piperidine)-N-oxide. Group: Biochemicals. Alternative Names: 4- [ (4-Methyl-4-oxido-1-piperazinyl) methyl] -N- [4-methyl-3- [ [4- (3-pyridinyl) -2-pyrimidinyl] amino] phenyl] benzamide; CGP 71422. Grades: Highly Purified. CAS No. 571186-91-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C29H31N7O2. US Biological Life Sciences.
Worldwide
Imatinib (Pyridine)-N-oxide
matinib (Pyridine)-N-oxide is an impurity of Imatinib (Gleevec). Imatinib impurity A. Group: Biochemicals. Alternative Names: N- [4-Methyl-3- [ [4- (1-oxido-3-pyridinyl) -2-pyrimidinyl] amino] phenyl] -4- [ (4-methyl-1-piperazinyl) methyl] benzamide; CGP 72383. Grades: Highly Purified. CAS No. 571186-92-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Imatinib (STI571)
Imatinib is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy. Group: Inhibitors. Alternative Names: STI571, CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 250mg. Product ID: S2475. Formula: C29H31N7O. Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Imatinib (STI571) Mesylate
Imatinib Mesylate is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy. Group: Inhibitors. Alternative Names: CGP-57148B,STI571. CAS No. 220127-57-1. Pack Sizes: 250mg. Product ID: S1026. Formula: C29H31N7O.CH4SO3. Smiles: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Imatinib USP Impurity A
Imatinib USP Impurity A. Uses: For analytical and research use. CAS No. 55314-16-4. Molecular formula: C10H12N2O. Mole weight: 176.22. Catalog: APB55314164.