A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Iloperidone impurity 32. Uses: For analytical and research use. Molecular formula: C12H12F2N2O2. Mole weight: 254.24. Catalog: APB11911.
Iloperidone impurity 33
Iloperidone impurity 33. Uses: For analytical and research use. Molecular formula: C12H13F2NO2. Mole weight: 241.24. Catalog: APB11913.
Iloperidone impurity 34
Iloperidone impurity 34. Uses: For analytical and research use. Molecular formula: C12H14F2N2O2. Mole weight: 256.25. Catalog: APB11914.
Iloperidone impurity 35
Iloperidone impurity 35. Uses: For analytical and research use. CAS No. 133455-04-6. Molecular formula: C25H29FN2O4. Mole weight: 440.52. Catalog: APB133455046.
Iloperidone impurity 36
Iloperidone impurity 36. Uses: For analytical and research use. CAS No. 792857-93-3. Molecular formula: C12H14ClNO. Mole weight: 223.7. Catalog: APB792857933.
Iloperidone impurity 37
Iloperidone impurity 37. Uses: For analytical and research use. Molecular formula: C24H28N2O5. Mole weight: 424.5. Catalog: APB11915.
Iloperidone impurity 38
Iloperidone impurity 38. Uses: For analytical and research use. CAS No. 64603-90-3. Molecular formula: C6H9NO2. Mole weight: 127.14. Catalog: APB64603903.
Iloperidone impurity 4
Iloperidone impurity 4. Uses: For analytical and research use. CAS No. 84163-68-8. Molecular formula: C12H14N2O. Mole weight: 202.26. Catalog: APB84163688.
Iloperidone impurity 5
Iloperidone impurity 5. Uses: For analytical and research use. CAS No. 84163-22-4. Molecular formula: C12H15ClN2O. Mole weight: 238.72. Catalog: APB84163224.
Iloperidone impurity 6
Iloperidone impurity 6. Uses: For analytical and research use. CAS No. 2379325-11-6. Molecular formula: C24H25F2N3O2. Mole weight: 425.48. Catalog: APB2379325116.
Iloperidone impurity 7
Iloperidone impurity 7. Uses: For analytical and research use. Molecular formula: C24H26F2N4O2. Mole weight: 440.49. Catalog: APB11907.
Iloperidone impurity 9
Iloperidone impurity 9. Uses: For analytical and research use. CAS No. 64671-29-0. Molecular formula: C12H15ClFNO. Mole weight: 243.71. Catalog: APB64671290.
Iloperidone metabolite Hydroxy Iloperidone
Iloperidone metabolite Hydroxy Iloperidone (P88; Hydroxy Iloperidone) is an active reduced metabolite of Iloperidone (HY-17410). Iloperidone metabolite Hydroxy Iloperidone can be used for the research of schizophrenia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: P88; Hydroxy Iloperidone. CAS No. 133454-55-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-G0003.
Iloperidone metabolite P95
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors with mean Ki values of 7.08, 21.38, 83.18, and 47.86 nM, respectively, but does not cross the blood-brain barrier. Category: Active pharmaceutical ingredients. CAS No. 475110-48-6. Product ID: API475110486. Molecular formula: C23H25FN2O5. Mole weight: 428.46.
Iloprost
A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension. It has a role as a platelet aggregation inhibitor and a vasodilator agent. Category: Active pharmaceutical ingredients. Synonyms: Ciloprost. Ventavis. Endoprost. Ilomedin. CAS No. 78919-13-8. Product ID: API78919138. Molecular formula: C22H32O4. Mole weight: 360.5. EINECS: 636-055-8. SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O. Appearance: Colourless to Pale Yellow Oil to Solid.
Iloprost
Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ciloprost; ZK 36374. CAS No. 78919-13-8. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0096.
Ilorasertib hydrochloride
Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-348 hydrochloride. CAS No. 1847485-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16018A.
ILP
ILP is an analog of insulin, a pancreatic hormone that regulates glucose metabolism, cellular uptake, as well as the storage of glucose, amino acids and fatty acids. Synonyms: Insulin-like peptide; Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Asp-Leu-Ala-Asp-Asn-Ile-Glu-Arg-Leu-Lys-Ala-Asn-Asp-Gly-Leu-Lys-Phe-Ser-Gln-Glu-Tyr-Glu-Ser-Ile-NH2. Molecular formula: C178H303N65O54S. Mole weight: 4250.00.
ILS-920
ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin FKBP52 and to the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for FKBP52 versus FKBP12[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 892494-07-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106345.
Ilunocitinib
Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3411067. CAS No. 1187594-14-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132819.
Ilutinib impurity 10
Ilutinib impurity 10. Uses: For analytical and research use. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. Catalog: APB1022150113.
Ilutinib impurity 11
Ilutinib impurity 11. Uses: For analytical and research use. CAS No. 1642630-12-3. Molecular formula: C22H22N6O. Mole weight: 386.46. Catalog: APB1642630123.
Ilutinib impurity 12
Ilutinib impurity 12. Uses: For analytical and research use. CAS No. 2213398-75-3. Molecular formula: C18H15N5O. Mole weight: 317.35. Catalog: APB2213398753.
Ilutinib impurity 13
Ilutinib impurity 13. Uses: For analytical and research use. CAS No. 1899859-31-4. Molecular formula: C20H25NO5. Mole weight: 359.42. Catalog: APB1899859314.
Ilutinib impurity 14
Ilutinib impurity 14. Uses: For analytical and research use. CAS No. 2244619-11-0. Molecular formula: C28H28N6O4. Mole weight: 512.57. Catalog: APB2244619110.
Ilutinib impurity 15
Ilutinib impurity 15. Uses: For analytical and research use. Molecular formula: C50H48N12O4. Mole weight: 881.01. Catalog: APB11051.
Ilutinib impurity 16
Ilutinib impurity 16. Uses: For analytical and research use. Molecular formula: C50H48N12O4. Mole weight: 881.01. Catalog: APB11050.
Ilutinib impurity 17
Ilutinib impurity 17. Uses: For analytical and research use. CAS No. 2417548-83-3. Molecular formula: C50H48N12O4. Mole weight: 881.01. Catalog: APB2417548833.
Ilutinib impurity 18
Ilutinib impurity 18. Uses: For analytical and research use. Molecular formula: C50H48N12O4. Mole weight: 881.01. Catalog: APB11052.
Ilutinib impurity 19
Ilutinib impurity 19. Uses: For analytical and research use. Molecular formula: C23H24N6O3S. Mole weight: 464.54. Catalog: APB11053.
Ilutinib impurity 3
Ilutinib impurity 3. Uses: For analytical and research use. CAS No. 1839099-22-7. Molecular formula: C25H26N6O2. Mole weight: 442.52. Catalog: APB1839099227.
Ilutinib impurity 4
Ilutinib impurity 4. Uses: For analytical and research use. Molecular formula: C50H50N12O4. Mole weight: 883.03. Catalog: APB11044.
Ilutinib impurity 5
Ilutinib impurity 5. Uses: For analytical and research use. Molecular formula: C25H26N6O3. Mole weight: 458.52. Catalog: APB11045.
Ilutinib impurity 6
Ilutinib impurity 6. Uses: For analytical and research use. Molecular formula: C28H28N6O4. Mole weight: 512.57. Catalog: APB11046.
Ilutinib impurity 7
Ilutinib impurity 7. Uses: For analytical and research use. Molecular formula: C37H47N7O5. Mole weight: 669.83. Catalog: APB11047.
Ilutinib impurity 8
Ilutinib impurity 8. Uses: For analytical and research use. Molecular formula: C33H24N8O3. Mole weight: 580.61. Catalog: APB11048.
Ilutinib impurity 9
Ilutinib impurity 9. Uses: For analytical and research use. Molecular formula: C32H22N8O2. Mole weight: 550.58. Catalog: APB11049.
Iluzanebart
Iluzanebart is a human monoclonal IgG1 antibody and is the agonist antibody for human TREM2 (hTREM2). Iluzanebart improves the survival and function of microglia by activating the TREM2 signaling pathway to compensate for the loss of CSF1R function. Iluzanebart can be used for research of adult-onset leukoencephalopathy associated with CSF1R (colony stimulating factor 1 receptor) (CSF1R-ALSP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VGL101. CAS No. 2733621-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990043.
Im-1
Im-1 is an antibacterial peptide isolated from Isometrus maculatus (Lesser brown scorpion). It has activity against gram-positive bacteria, gram-negative bacteria and Parasites. Synonyms: Phe-Ser-Phe-Lys-Arg-Leu-Lys-Gly-Phe-Ala-Lys-Lys-Leu-Trp-Asn-Ser-Lys-Leu-Ala-Arg-Lys-Ile-Arg-Thr-Lys-Gly-Leu-Lys-Tyr-Val-Lys-Asn-Phe-Ala-Lys-Asp-Met-Leu-Ser-Glu-Gly-Glu-Glu-Ala-Pro-Pro-Ala-Ala-Glu-Pro-Pro-Val-Glu-Ala-Pro-Gln. Molecular formula: C292H467N79O77S. Mole weight: 6348.46.
IM-12
IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling. Uses: Scientific research. Category: Signaling pathways. CAS No. 1129669-05-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12292.
IM-54
IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 861891-50-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108351.
IMAB027
IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP1650. CAS No. 1650599-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99413.
iMAC2
iMAC2. Group: Biochemicals. Grades: Purified. CAS No. 335166-00-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
iMAC2 hydrochloride
iMAC2 hydrochloride is a potent MAC (mitochondrial apoptosis-induced channel) inhibitor, with an IC50 of 28 nM and a LD50 of 15000 nM. iMAC2 hydrochloride shows anti-apoptotic effect. iMAC2 hydrochloride blocks cytochrome c release[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 335166-00-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110073.
Imalumab
Imalumab (BAX69) is a recombinant, human IgG1 monoclonal antibody that targets macrophage inhibitory factor (MIF). Imalumab can be used for the research of ovarian carcinoma, recurrent malignant ascites and cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAX69; Anti-Human MIF Recombinant Antibody. CAS No. 1430205-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99262.
Imaradenant
AZD4635 (HTL1071) is a potent, selective and orally active adenosine A2A receptor (A2AR) antagonist. AZD4635 binds to human A2AR with a Ki of 1.7 nM and shows >30-fold selectivity over other adenosine receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HTL1071; AZD4635. CAS No. 1321514-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101980.
Imatinib
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Synonyms: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. Grade: >98%. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.60.
Imatinib
Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571; CGP-57148B. CAS No. 152459-95-5. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15463.
Imatinib-[d3]
Imatinib-[d3] is the labelled analogue of Imatinib. Imatinib can be used for the treatment of chronic myelogenous leukemia and acute lymphocytic leukemia. Synonyms: Imatinib D3; Genfatinib-d3; 4-[[4-(methyl-d3)-1-piperazinyl]methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. Grade: 95% by HPLC; 99% atom D. CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.62.
Imatinib-d4
Imatinib-d4 (STI571-d4) is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571 d4; CGP-57148B d4. CAS No. 1134803-16-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15463S1.
Imatinib-[d4]
Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Synonyms: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4; Imatinib D4. Grade: ≥98% (HPLC). CAS No. 1134803-16-9. Molecular formula: C29H27D4N7O. Mole weight: 497.64.
Imatinib-d8
Imatinib-d8 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: STI571-d8; CGP-57148B-d8. CAS No. 1092942-82-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-15463S.
Imatinib-d8
Imatinib-d8 is a deuterated tyrosine kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092942-82-9. Pack Sizes: 1mg, 10mg. Molecular Formula: C29H23D8N7O. US Biological Life Sciences.
Worldwide
Imatinib-[d8]
Imatinib-[d8] is the labelled analogue of Imatinib, a treatment of chronic myeloid leukemia. Synonyms: Imatinib D8; 4-[(4-Methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; Genfatinib-d8. Grade: 95% by HPLC; 95% atom D. CAS No. 1092942-82-9. Molecular formula: C29H23D8N7O. Mole weight: 501.65.
A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). Group: Biochemicals. Alternative Names: Imatinib-d8 Methanesulfonate, STI-571-d8, CGP-57148B-d8, Glivec-d8. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Imatinib Dimer Impurity
Imatinib Dimer Impurity. Uses: For analytical and research use. CAS No. 1365802-18-1. Molecular formula: C52H48N12O2. Mole weight: 873.04. Catalog: APB1365802181.
Imatinib EP Impurity B HCl
Imatinib EP Impurity B HCl. Uses: For analytical and research use. CAS No. 581076-67-7. Molecular formula: C21H29ClN6O. Mole weight: 416.95. Catalog: APB581076677.
Imatinib EP Impurity C-D8
Imatinib EP Impurity C-D8. Uses: For analytical and research use. CAS No. 1185103-28-9. Molecular formula: C28H21D8N7O. Mole weight: 487.64. Catalog: APB1185103289.
Imatinib EP Impurity D
Imatinib EP Impurity D. Uses: For analytical and research use. CAS No. 1821122-73-9. Molecular formula: C53H51N12O2. Mole weight: 888.07. Catalog: APB1821122739.
Imatinib EP Impurity H
Imatinib EP Impurity H. Uses: For analytical and research use. CAS No. 350-03-8. Molecular formula: C7H7NO. Mole weight: 121.14. Catalog: APB350038.
Imatinib, Free base
An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC50=0.5nm), phosphorylation of a fusion protein (IC50=30nm), and viability of BaF3 cells expressing Rhe-PDGFRa in the absence of IL-3 (IC50 =0.17nm). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100ug, 1g. US Biological Life Sciences.
Worldwide
Imatinib Imidazole Impurity
Imatinib Imidazole Impurity. Uses: For analytical and research use. CAS No. 1256080-10-0. Molecular formula: C32H31N9O2. Mole weight: 573.66. Catalog: APB1256080100.
Imatinib Impurity 11
Imatinib Impurity 11. Uses: For analytical and research use. CAS No. 796738-71-1. Molecular formula: C16H13N5O2. Mole weight: 307.31. Catalog: APB796738711.
Imatinib Impurity 12
Imatinib Impurity 12. Uses: For analytical and research use. CAS No. 112696-91-0. Molecular formula: C16H15N5. Mole weight: 277.33. Catalog: APB112696910.
Imatinib Impurity 16
Imatinib Impurity 16. Uses: For analytical and research use. CAS No. 152460-09-8. Molecular formula: C16H13N5O2. Mole weight: 307.31. Catalog: APB152460098.
Imatinib Impurity 17
Imatinib Impurity 17. Uses: For analytical and research use. CAS No. 1802325-93-4. Molecular formula: C20H22N2O4. Mole weight: 354.41. Catalog: APB1802325934.
Imatinib Impurity 18
Imatinib Impurity 18. Uses: For analytical and research use. CAS No. 404844-11-7. Molecular formula: C24H20ClN5O. Mole weight: 429.91. Catalog: APB404844117.
Imatinib Impurity 2
Imatinib Impurity 2. Uses: For analytical and research use. CAS No. 1384131-91-2. Molecular formula: C7H11NO. Mole weight: 125.17. Catalog: APB1384131912.
Imatinib Impurity 26
Imatinib Impurity 26. Uses: For analytical and research use. CAS No. 74231-65-5. Molecular formula: C8H5Cl2N. Mole weight: 186.04. Catalog: APB74231655.
Imatinib Impurity 27
Imatinib Impurity 27. Uses: For analytical and research use. CAS No. 67013-55-2. Molecular formula: C8H5Br2N. Mole weight: 274.94. Catalog: APB67013552.