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| Product | Description | |
|---|---|---|
| ML 9 hydrochloride | ML 9 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 105637-50-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| M-LAURYL SULFATE BROTH | M-LAURYL SULFATE BROTH. Product ID: ACMA00006845. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| M-LAURYL SULFATE BROTH, VEGITONE | M-LAURYL SULFATE BROTH, VEGITONE. Product ID: ACMA00006846. Alfa Chemistry - ISO 9001:32057 Certified. | |
| MLCK inhibitor peptide | MLCK inhibitor peptide. Group: Biochemicals. Grades: Purified. CAS No. 198694-74-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MLCK inhibitor peptide 18 | MLCK inhibitor peptide 18. Group: Biochemicals. Grades: Purified. CAS No. 224579-74-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MLCK inhibitor peptide 18 | MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations. Uses: Scientific research. Category: Signaling pathways. CAS No. 224579-74-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1029. |  |
| MLCK inhibitor peptide 18 | A myosin light chain kinase (MLCK) inhibitor (IC50= 50 nM), and inhibits CaM kinase IIonly at 4000-fold higher concentrations. Alternative Names: Myosin Light Chain Kinase Inhibitor Peptide 18. Grades: ≥95%. CAS No. 224579-74-2. Molecular formula: C60H105N23O11. Mole weight: 1324.64. |  |
| MLCK inhibitor peptide 18 acetate | MLCK inhibitor peptide 18 acetate is a selective competitive myosin light chain kinase (MLCK) inhibitor (IC50 = 50 nM) that inhibits CaM kinase II only at 4000-fold higher concentrations. Alternative Names: H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2.CH3CO2H; L-arginyl-L-lysyl-L-lysyl-L-tyrosyl-L-lysyl-L-tyrosyl-L-arginyl-L-arginyl-L-lysinamide acetate. Grades: ≥95%. Molecular formula: C62H109N23O13. Mole weight: 1384.67. | |
| MLH3 protein, partial (135-151) | MLH3 protein, partial (135-151) is a 7-aa peptide. MLH3 is a DNA mismatch repair gene associated with mammalian microsatellite instability. | |
| MLi-2 | MLi-2, a chemical probe, is an orally active and highly selective LRRK2 inhibitor with an IC50 of 0.76 nM. MLi-2 has the potential for Parkinsons disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627091-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100411. | |
| MLi-2 | MLi-2 is a potent, orally available and brain penetrant inhibitor of LRRK2 (IC50 = 0.76 nM) with excellent selectivity that shows >295-fold selectivity for over 300 kinases and a diverse panel of receptors and ion channels. Alternative Names: Merck lrrk2 inhibitor-2; MLi 2; MLi2; rel-3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole. Grades: 98%. CAS No. 1627091-47-7. Molecular formula: C21H25N5O2. Mole weight: 379.46. | |
| MLKL-IN-6 | MLKL-IN-6 (compound P28) is a mixed lineage kinase inhibitor targeting Mixed Lineage Kinase domain-like (MLKL). MLKL-IN-6 inhibits cell necrosis. MLKL-IN-6 inhibits MLKL phosphorylation and oligomerization during cell necrosis, inhibits immune cell death, and reduces the expression of adhesion factors. MLKL-IN-6 has low cytotoxicity, and it inhibits hepatic stellate cell activation, reduces liver fibrosis marker levels, and has anti-fibrotic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3080148-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156119. | |
| mlmp3 (D81N) | mlmp3 (D81N). Alternative Names: Ala-Ala-Leu-Leu-Asn-Lys-Leu-Tyr-Ala. Molecular formula: C46H77N11O12. Mole weight: 976.23. | |
| MLN0128 | MLN0128, also known as INK128, is a TORC1/2 inhibitor, is also an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity. TORC1/2 inhibitor INK128 binds to and inhibits both TORC1 and TORC2 complexes of mTOR, which may result in tumor cell apoptosis and a decrease in tumor cell proliferation. TORC1 and 2 are upregulated in some tumors and play an important role in the PI3K/Akt / mTOR signaling pathway, which is frequently dysregulated in human cancers. Alternative Names: TAK-228; TAK 228; TAK228; INK128; INK-128; INK 128; MLN0128; MLN 0128; MLN-0128; Sapanisertib. Grades: >98%. CAS No. 1224844-38-5. Molecular formula: C15H15N7O. Mole weight: 309.333. | |
| MLN0905 | MLN0905 is a potent, orally active Polo-like kinase 1 (PLK1) inhibitor. MLN0905 has inhibitory potency against PLK1 with an IC50 value of 2 nM. MLN0905 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228960-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15155. | |
| MLN120B | MLN120B (ML120B) is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM. MLN120B inhibits multiple myeloma cell growth in vitro and in vivo and also can be used for the research of rheumatoid arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML120B. CAS No. 783348-36-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15473. | |
| MLN120B dihydrochloride | MLN120B dihydrochloride (ML120B dihydrochloride) is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM. MLN120B inhibits multiple myeloma cell growth in vitro and in vivo and also can be used for the research of rheumatoid arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML120B dihydrochloride. CAS No. 1782573-78-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15473A. | |
| MLN2238 (Ixazomib) | Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3. Group: Inhibitors. CAS No. 1072833-77-2. Pack Sizes: 5mg. Product ID: S2180. Formula: C14H19BCl2N2O4. Smiles: B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| MLN-4760 | MLN-4760 is a potent and selective human ACE2 inhibitor (IC50, 0.44 nM), with excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypeptidase A (CPDA; IC50, 27 μM). Uses: Scientific research. Category: Signaling pathways. CAS No. 305335-31-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19414. | |
| MLN 4924 | A potent and selective inhibitor of NAE. Group: Biochemicals. Alternative Names: Sulfamic Acid [ (1S, 2S, 4R) -4- [4- [ [ (1S) -2, 3-dihydro-1H-inden-1-yl] amino] -7H-pyrrolo [2, 3-d] pyrimidin-7-yl] -2-hydroxycyclopentyl] methyl Ester. Grades: Highly Purified. CAS No. 905579-51-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| MLN4924 (Pevonedistat) | MLN4924 is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with IC50 of 4 nM. Group: Inhibitors. CAS No. 905579-51-3. Pack Sizes: 2mg. Product ID: S7109. Formula: C21H25N5O4S. Smiles: C1CC2=CC=CC=C2C1NC3=C4C=CN(C4=NC=N3)C5CC(C(C5)O)COS(=O)(=O)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| MLN8054 | MLN8054 is a potent, selective and orally available aurora A kinase inhibitor with an IC50 of 4 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 869363-13-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10180. | |
| MLN8054 | MLN8054 is an aurora kinase inhibitor MLN8054, which is an orally bioavailable, highly selective small molecule inhibitor of the serine / threonine protein kinase Aurora A kinase with potential antineoplastic activity. Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation. Aurora A localizes in mitosis to the spindle poles and to spindle microtubules and is thought to regulate spindle assembly. Aberrant expression of Aurora kinases occurs in a wide variety of cancers, including colon and breast cancers. Alternative Names: MLN8054; MLN 8054; MLN-8054. CAS No. 869363-13-3. Molecular formula: C25H15ClF2N4O2. Mole weight: 476.86. | |
| MLN 8237 | Antagonist of Aurora A serine/threonine protein kinase; antineoplastic. Group: Biochemicals. Alternative Names: 4-[[9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-benzoic acid; Alisertib. Grades: Highly Purified. CAS No. 1028486-01-2. Pack Sizes: 10mg. Molecular Formula: C27H20ClFN4O4, Molecular Weight: 518.92. US Biological Life Sciences. | Worldwide |
| MLN-9708 | ixazomib is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated. Alternative Names: Ixazomib; MLN-9708; MLN 9708; MLN9708. CAS No. 1201902-80-8. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. | |
| MLR 1023 | MLR 1023. Group: Biochemicals. Grades: Purified. CAS No. 41964-07-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| mLR12 | mLR12 is a Trem1 inhibitory peptide. mLR12 decreases aortic rupture rate in BAPN-induced Thoracic aortic aneurysm and dissection (TAAD) mice model[1]. Uses: Scientific research. Category: Peptides. CAS No. 3033299-76-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P5521. | |
| MLR-52 | MLR-52, extracted from Streptomyces sp. AB 1869R-359, is an immunosuppressive protein kinase C inhibitor. And the IC50 (nmol/L) of the mixed lymphocyte response test was 1.9±0.2. Alternative Names: 4'-Demethylamino-4',5'-dihydroxystaurosporine; (+)-MLR-52. CAS No. 155416-34-5. Molecular formula: C27H23N3O5. Mole weight: 469.49. | |
| MLS000532223 | MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16616-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117149. | |
| MLS000536924 | MLS000536924 is a potent and selective inhibitor of human epithelial 15-lipoxygenase-2 with competitive activity. MLS000536924 exhibits more than 50-fold selectivity in inhibiting h15-LOX-2 and can be effectively applied to study its role in atherosclerosis, cystic fibrosis, and ferroptosis. The binding mode of MLS000536924 shows stronger restriction of protein movement than other inhibitors, further verifying its higher biological activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 511306-37-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116919. | |
| MLS001006105 | MLS001006105 (ZINC13684400) is a GPR65 allosteric agonist. MLS001006105 displays GPR65 allosteric agonist activity at pH 8.40 but not at lower pH[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZINC13684400. CAS No. 455310-36-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W193844. | |
| MLS0315771 | MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 727664-91-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112945. | |
| MLS-0437605 | MLS-0437605 is a selective dual-specificity phosphatase 3 (DUSP3) inhibitor with an IC50 of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862975-18-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123846. | |
| MLS 1547 | MLS 1547 is a dopamine D2 receptor agonist. It may be used in the combination with antipsychotic drugs. Alternative Names: MLS 1547; MLS1547; MLS-1547; 5-Chloro-7-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-8-quinolinol. Grades: ≥98% by HPLC. CAS No. 315698-36-3. Molecular formula: C19H19ClN4O. Mole weight: 354.83. | |
| ML SA1 | ML SA1. Group: Biochemicals. Grades: Purified. CAS No. 332382-54-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| ML-SA1 | ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 332382-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108462. | |
| ML-SA1 | ML SA1 is an activator of TRPML channels. It can induce TRPML-mediated Ca2+ release from lysosomes and reduce cholesterol accumulation in Niemann-Pick type C macrophages. Alternative Names: ML SA1; ML-SA1; 2-[2-oxo-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl]-1H-isoindole-1,3(2H)-dione; 2-(2-oxo-2-(2,2,4-Trimethyl-3,4-dihydroquinolin-1(2H)-yl)ethyl)isoindoline-1,3-dione; 2-[2-Oxo-2-(2,2,4-trimethyl-3,4-dihydro-2H-quinolin-1-yl)-ethyl]-isoindole-1,3-dione; 2-[2-keto-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindoline-1,3-quinone;2-[2-oxidanylidene-2-(2,2,4-trimethyl-3,4-dihydroquinolin-1-yl)ethyl]isoindole-1,3-dione; 1-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-1,2,3,4-tetrahydro-2,2,4-trimethyl-quinoline;2-[2-oxo-2-(2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-1-yl)ethyl]-2,3-dihydro-1H-isoindole-1,3-dione; 2-{2-oxo-2-[2,2,4-trimethyl-3,4-dihydro-1(2H)-quinolinyl]ethyl}-1H-isoindole-1,3(2H)-dione;quinoline, 1-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-1,2,3,4-tetrahydro-2,2,4-trimethyl-. Grades: 95%. CAS No. 332382-54-4. Molecular formula: C22H22N2O3. Mole weight: 362.43. | |
| ML-SA5 | ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2418670-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152182. | |
| ML-SI3 | ML-SI3 is a mixture of cis/trans ML-SI3 (HY-139426A), which is a TRPML1/2 channel inhibitor with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 also inhibits lysosomal calcium efflux and blocks downstream TRPML1-mediated autophagy. The cis/trans ML-SI3 (HY-139426A) components of ML-SI3 are TRPML2 activators with EC50s of 3.3 μM and 9.4 μM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML-SI3 (cis/trans mix). CAS No. 891016-02-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139426. | |
| ML-SI3 | ML-SI3 is an antagonist of the TRPML family of calcium channels. ML-SI3 can prevent lysosomal calcium efflux and has been reported to block downstream TRPML1-mediated induction of autophagy. Alternative Names: N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]benzenesulfonamide. Grades: 98%. CAS No. 891016-02-7. Molecular formula: C23H31N3O3S. Mole weight: 429.58. | |
| ML-T7 | ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 459789-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163028. | |
| MLT-943 | MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar IC50 across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood). MLT-943 has anti-inflammatory activities and can be used for FcgR-mediated inflammation research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832576-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134820. | |
| MLT-985 | MLT-985 is a selective allosteric and orally active MALT1 inhibitor with an IC50 value of 3 nM. MLT-985 can suppress cell growth and aberrant CARD11/BCL10/MALT1 complex signaling. MLT-985 can be used for the research of cancer, such as B cell malignancies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832576-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142648. | |
| Mlu I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. A↑CGCGT TGCGC↓A. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Micrococcus luteus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1133RE. |  |
| Mly113 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 80% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GG↑CGCC CCGC↓GG. Activity: 2000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Micrococcus lylae 113. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1134RE. | |
| MM0299 | MM0299 is a selective lanosterol synthase (LSS) inhibitor with an IC50 value of 2.22 μM. MM0299 depletes intracellular cholesterol and acts as a growth inhibitor for glioma stem-like cells. MM0299 exhibits anti-glioblastoma activity. MM0299 is applicable to research related to glioblastoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 474255-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160972. | |
| MM 07 | MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart. Uses: Scientific research. Category: Signaling pathways. CAS No. 1876450-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108003. | |
| MM 102 | MM 102. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MM-102 | MM-102 Inhibitor. Uses: Scientific use. Product Category: T8768. CAS No. 1883545-52-5. |  |
| MM-102 | MM-102 (HMTase Inhibitor IX) is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction (IC50=2.4 nM). MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer (SCNT) embryos[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMTase Inhibitor IX. CAS No. 1417329-24-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12220. | |
| MM-102 | MM-102, as a MLL1 mimetic, shows high binding affinities to WDR5 with IC50 of 2.9 nM and Ki of < 1 nM. Alternative Names: MM-102; MM102; MM 102; HMTase Inhibitor IX. Grades:>98%. CAS No. 1417329-24-8. Molecular formula: C35H49F2N7O4. Mole weight: 669.8. | |
| MM-102 TFA | MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is>200 times more potent than the ARA peptide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMTase Inhibitor IX TFA. CAS No. 1883545-52-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12220A. | |
| MM11253 | MM11253 is a potent and selective RARγ antagonist with an IC50 of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 345952-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108530. | |
| MM 11253 | MM 11253. Group: Biochemicals. Grades: Purified. CAS No. 345952-44-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MM 14201 | It is produced by the strain of Streptomyces sp. NCIB 11813. MM 14201 has a broad spectrum of antibacterial activity, especially against the bacteria of Serratia and Pseudomonas. Alternative Names: MM-14201; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 3-amino-5-hydroxy-, (1S-(1alpha,5beta,6alpha))-. CAS No. 89020-30-4. Molecular formula: C6H7NO3. Mole weight: 141.12. | |
| MM-17880 | MM-17880 is originally isolated from Streptomyces olivaceus. It has anti-gram-positive and anti-gram-negative bacteria activities. Combined with amoxycillin, it has a synergistic antibacterial effect on Staphylococcus aureus and Klebsiella pneumoniae. Alternative Names: (5R)-3-[[2-(Acetylamino)ethyl]thio]-6α-[(S)-1-(sulfooxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid disodium salt. CAS No. 61036-81-5. Molecular formula: C13H16N2Na2O8S2. Mole weight: 438.38. | |
| MM-206 | MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809581-87-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121725. | |
| MM3122 | MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2574390-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-148072. | |
| MM-401 TFA | MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1442106-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-19554A. | |
| MM 42842 | MM 42842 is originally isolated from Pseudomonas cocovenenans and has weak activity against gram-positive bacteria. Alternative Names: MM-42842. Grades: >98%. CAS No. 113784-28-4. Molecular formula: C13H22N4O9S. Mole weight: 410.40. | |
| MM 46115 | MM 46115 is produced by the strain of Actinomadura pelletieri. It has anti-parainfluenza virus 1 and 2 and anti-gram-positive bacteria activities. Alternative Names: MM-46115; 17-O-(4-((3-Chloro-6-hydroxy-2-methylbenzoyl)amino)-2,3,4,6-tetradeoxy-3-(dimethylamino)-beta-D-lyxo-hexopyranosyl)-22-de(hydroxymethyl)-8,14,23-tridemethyl-12-ethyl-8-hydroxy-23-propylkijanolide. CAS No. 132054-37-6. Molecular formula: C50H67ClN2O10. Mole weight: 891.52. | |
| MM 47755 | MM 47755 is produced by the strain of greysporing streptomycete. It has anti-Gram-negative bacteria and fungi activity (100μg/ mL). Alternative Names: 6-Deoxy-8-O-methylrabelomycin; (-)-3,4-Dihydro-3-hydroxy-8-methoxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione; MM-47755; Benz(a)anthracene-1,7,12(2H)-trione, 3,4-dihydro-3-hydroxy-8-methoxy-3-methyl-, (-)-. Grades: 95%. CAS No. 117620-87-8. Molecular formula: C20H16O5. Mole weight: 336.34. | |
| MM 49721 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria. Alternative Names: MM-49721; Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-10,19-didechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)-. CAS No. 126985-52-2. Molecular formula: C72H87N9O28. Mole weight: 1526.50. | |
| MM 54 | MM 54 (compound 5) is a competitive antagonist at APJ, with an IC50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1313027-43-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2271. | |
| MM 54 | MM 54 is an apelin receptor antagonist with IC50 value of 93 nM. It can antagonize the inhibitory effect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Alternative Names: MM-54; MM54; H-Cys(1)-Arg-Pro-Arg-Leu-Cys(1)-Lys-His-Cys(2)-Arg-Pro-Arg-Leu-Cys(2)-OH; L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteinyl-L-lysyl-L-histidyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteine (1->6),(9->14)-bis(disulfide). Grades: ≥95%. CAS No. 1313027-43-8. Molecular formula: C70H121N29O15S4. Mole weight: 1737.15. | |
| MM 55266 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Alternative Names: MM-55266; Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-(2-deoxy-2-((7-methyl-1-oxooctyl)amino)-alpha-D-glucopyranuronosyl)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-20-4. Molecular formula: C86H89Cl5N8O35. Mole weight: 1971.92. | |
| MM-55268 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Alternative Names: Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-((2-deoxy-2-((1-oxodecyl)amino)-alpha-D-glucopyranuronosyl)amino)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-19-1. Molecular formula: C87H91Cl5N8O35. Mole weight: 1985.95. | |
| MM 77 dihydrochloride | MM 77 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 159187-70-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MMAD | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. Uses: Adcs cytotoxin. Alternative Names: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. Grades: ≥98.0% (HPLC). CAS No. 203849-91-6. Molecular formula: C41H66N6O6S. Mole weight: 771.06. | |
| MMAD | MMAD is a potent tubulin inhibitor, is a toxin payload in antibody agent conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. CAS No. 203849-91-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15581. | |
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