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| Product | Description | |
|---|---|---|
| Mannostatin B | Mannostatin B. Group: Biochemicals. Alternative Names: (1R,2R,3R,4S,5R)-4-Amino-5-[(R)-methylsulfinyl]-1,2,3-cyclopentanetriol. Grades: Highly Purified. CAS No. 102822-66-2. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C6H13NO4S. US Biological Life Sciences. |  Worldwide |
| mannosyl-3-phosphoglycerate phosphatase | Requires Mg2+. The enzyme from Pyrococcus horikoshii is specific for α-D-mannosyl-3-phosphoglycerate and forms part of the pathway for the synthesis of mannosylglycerate. Group: Enzymes. Enzyme Commission Number: EC 3.1.3.70. CAS No. 393512-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3675; mannosyl-3-phosphoglycerate phosphatase; EC 3.1.3.70; 393512-74-8. Cat No: EXWM-3675. |  |
| mannosyl-3-phosphoglycerate synthase | Requires Mg2+. The enzyme is absolutely specific for GDPmannose and 3-phosphoglycerate, and transfers the mannosyl group with retention of configuration. In the hyperthermophilic archaeon Pyrococcus horikoshii, the mannosyl-3-phosphoglycerate formed is subsequently dephosphorylated by a specific phosphatase, EC 3.1.3.70 (mannosyl-3-phosphoglycerate phosphatase), producing mannosylglycerate. Group: Enzymes. Synonyms: MPG synthase; GDP-mannose:3-phosphoglycerate 3-α-D-mannosyltransferase. Enzyme Commission Number: EC 2.4.1.217. CAS No. 393512-63-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2445; mannosyl-3-phosphoglycerate synthase; EC 2.4.1.217; 393512-63-5; MPG synthase; GDP-mannose:3-phosphoglycerate 3-α-D-mannosyltransferase. Cat No: EXWM-2445. | |
| Mannosylceramide, alpha | Natural killer T cells (NKT cells) are important regulators of the immune system. They share properties of both innate as well as adaptive immunity. They express T cell receptors (TCR) on their surface consisting of an invariable α-chain and a somewhat variable β-chain. The majority of NKT cells express the invariable α-chain Vα14-Jα18 (Vα14) in mouse or its homolog in humans Vα24-Jα18 (Vα24). Vα14 NKT cells recognize α-GalCer presented by CD1d. NKT cells expressing the invariant Vα19-Jα26 TCR α-chain (Vα19 NKT cells) have been found in peripheral blood lymphocytes and in the liver. They recognize α-ManCer presented by MR1 (Major histocompatibility complex, class I-related) and respond with production of large amounts of immunoregulatory cytokines. Group: Biochemicals. Alternative Names: α-ManCer; α-Mannosyl Ceramide; (2S,3S,4R)-2-Amino-N-hexacosanoyl-1-O-(α-D-mannopyranosyl)-1,3,4-octadecanetriol; α-D-Galactopyranoside. Grades: Highly Purified. CAS No. 320610-63-7. Pack Sizes: 250ug, 1mg. Molecular Formula: C50H99NO9. US Biological Life Sciences. | Worldwide |
| mannosylfructose-phosphate phosphatase | This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ for activity. Mannosylfructose is the major endogenous osmolyte produced by several α-proteobacteria in response to osmotic stress and is synthesized by the sequential action of EC 2.4.1.246 (mannosylfructose-phosphate synthase) followed by this enzyme. While mannosylfructose 6-phosphate is the physiological substrate, the enzyme can use sucrose 6-phosphate very efficiently. The F in mannosylfructose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent. Group: Enzymes. Synonyms: mannosylfructose-6-phosphate phosphatase; MFPP. Enzyme Commission Number: EC 3.1.3.79. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3684; mannosylfructose-phosphate phosphatase; EC 3.1.3.79; mannosylfructose-6-phosphate phosphatase; MFPP. Cat No: EXWM-3684. | |
| mannosylfructose-phosphate synthase | This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity. GDP-mannose can be replaced by ADP-mannose but with a concomitant decrease in activity. The product of this reaction is dephosphorylated by EC 3.1.3.79 (mannosylfructose-phosphate phosphatase) to form the non-reducing disaccharide mannosylfructose, which is the major endogenous osmolyte produced by several α-proteobacteria in response to osmotic stress. The F in the product name is used to indicate that the fructose residue of sucrose carries the substituent. Group: Enzymes. Synonyms: mannosylfructose-6-phosphate synthase; MFPS. Enzyme Commission Number: EC 2.4.1.246. CAS No. 92480-04-1 (not distinguished from EC 2.4.1.167). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2475; mannosylfructose-phosphate synthase; EC 2.4.1.246; 92480-04-1 (not distinguished from EC 2.4.1.167); mannosylfructose-6-phosphate synthase; MFPS. Cat No: EXWM-2475. | |
| Mannosylglucosaminide | It is produced by the strain of Str. virginiae var. 4243-MTt1. It's an aminoglycoside antibiotic. It has anti-bacterium, mycobacterium and beer yeast effects. Trehalose does not counteract its antibacterial effect against Mycobacterium 607. Synonyms: Mannosyl glucosaminide; Antibiotic 4243; 1-O-(2-Amino-2-deoxy-α-D-gluco-hexopyranosyl)-α-D-manno-hexopyranose; Mannotrehalosamine. CAS No. 14510-04-4. Molecular formula: C12H23NO10. Mole weight: 341.31. |  |
| mannosylglucosyl-3-phosphoglycerate synthase | The enzyme is involved in synthesis of 2-[2-O-(α-D-mannopranosyl)-α-D-glucopyranosyl]-D-glycerate. Petrotoga miotherma and Petrotoga mobilis accumulate this compound in response to water stress imposed by salt. Group: Enzymes. Synonyms: MggA. Enzyme Commission Number: EC 2.4.1.270. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2502; mannosylglucosyl-3-phosphoglycerate synthase; EC 2.4.1.270; MggA. Cat No: EXWM-2502. | |
| mannosylglycerate hydrolase | The enzyme participates in the mannosylglycerate degradation pathway of some bacteria. Mannosylglycerate is phosphorylated during transport into the cell, and the phosphorylated form is hydrolysed by this enzyme. Group: Enzymes. Synonyms: 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase; α-mannosidase (ambiguous); mngB (gene name). Enzyme Commission Number: EC 3.2.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3853; mannosylglycerate hydrolase; EC 3.2.1.170; 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase; α-mannosidase (ambiguous); mngB (gene name). Cat No: EXWM-3853. | |
| mannosylglycerate synthase | Rhodothermus marinus can also form mannosylglycerate via a two-step pathway catalysed by EC 2.4.1.217 (mannosyl-3-phosphoglycerate synthase) and EC 3.1.3.70 (mannosyl-3-phosphoglycerate phosphatase). Depending on experimental conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate. Group: Enzymes. Enzyme Commission Number: EC 2.4.1.269. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2500; mannosylglycerate synthase; EC 2.4.1.269. Cat No: EXWM-2500. | |
| Mannosylglycerate synthase from Rhodothermus marinus, Recombinant | Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with system name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase. This enzyme catalyses the following chemical reaction: GDP-mannose + D-glycerate <-> GDP + 2-O-(alpha-D-mannopyranosyl) -D-glycerate. Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate. Group: Enzymes. Synonyms: GDP-Man:mannosylglycerate synthase; α-mannosyltransferase; GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase. Enzyme Commission Number: EC 2.4.1.-. Purity: > 95 % as judged by SDS-PAGE. Mannosylglycerate synthase. Mole weight: 47190.6 Da. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Rhodothermus marinus DSM 4252. GDP-Man:mannosylglycerate synthase; α-mannosyltransferase; GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase; Mannosylglycerate synthase; EC 2.4.1.-. Cat No: NATE-1216. | |
| mannosylglycoprotein endo-β-mannosidase | The substrate group is a substituent on N-4 of an asparagine residue in the glycoprotein. The mannose residue at the non-reducing end of the sequence may carry further α-D-mannosyl groups on O-3 or O-6, but such a substituent on O-3 of the β-D-mannosyl group prevents the action of the enzyme. The enzyme was obtained from the lily, Lilium longiflorum. Group: Enzymes. Synonyms: endo-β-mannosidase. Enzyme Commission Number: EC 3.2.1.152. CAS No. 141176-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3835; mannosylglycoprotein endo-β-mannosidase; EC 3.2.1.152; 141176-95-6; endo-β-mannosidase. Cat No: EXWM-3835. | |
| mannosyl-glycoprotein endo-β-N-acetylglucosaminidase | A group of related enzymes. Group: Enzymes. Synonyms: N,N'-diacetylchitobiosyl β-N-acetylglucosaminidase; endo-β-N-acetylglucosaminidase; mannosyl-glycoprotein endo-β-N-acetylglucosamidase; di-N-acetylchitobiosyl β-N-acetylglucosaminidase; endo-&beta. Enzyme Commission Number: EC 3.2.1.96. CAS No. 37278-88-9. Endo-β-N-acetylglucosaminidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3959; mannosyl-glycoprotein endo-β-N-acetylglucosaminidase; EC 3.2.1.96; 37278-88-9; N,N'-diacetylchitobiosyl β-N-acetylglucosaminidase; endo-β-N-acetylglucosaminidase; mannosyl-glycoprotein endo-β-N-acetylglucosamidase; di-N-acetylchitobiosyl β-N-acetylglucosaminidase; endo-β-acetylglucosaminidase; endo-β-(1?4)-N-acetylglucosaminidase; mannosyl-glycoprotein 1,4-N-acetamidodeoxy-β-D-glycohydrolase; endoglycosidase S; endo-N-acetyl-β-D-glucosaminidase; endo-N-acetyl-β-glucosaminidase; endo-β-N-acetylglucosaminidase D; endo-β-N-acetylglucosaminidase F; endo-β-N-acetylglucosaminidase H; endo-β-N-acetylglucosaminidase L; glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-β-glucosaminohydrolase; endoglycosidase H. Cat No: EXWM-3959. | |
| mannosyl-oligosaccharide 1,2-α-mannosidase | Involved in the synthesis of glycoproteins. Group: Enzymes. Synonyms: mannosidase 1A; mannosidase 1B; 1,2-α-mannosidase; exo-α-1,2-mannanase; mannose-9 processing α-mannosidase; glycoprotein processing mannosidase I; mannosidase I; Man9-mannosidase; ManI; 1,2-α-mannosyl-oligosaccharide α-D-mannohydrolase. Enzyme Commission Number: EC 3.2.1.113. CAS No. 9068-25-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3796; mannosyl-oligosaccharide 1,2-α-mannosidase; EC 3.2.1.113; 9068-25-1; mannosidase 1A; mannosidase 1B; 1,2-α-mannosidase; exo-α-1,2-mannanase; mannose-9 processing α-mannosidase; glycoprotein processing mannosidase I; mannosidase I; Man9-mannosidase; ManI; 1,2-α-mannosyl-oligosaccharide α-D-mannohydrolase. Cat No: EXWM-3796. | |
| mannosyl-oligosaccharide 1,2-α-mannosidase | Involved in the synthesis of glycoproteins. | |
| mannosyl-oligosaccharide 1,3-1,6-α-mannosidase | Involved in the synthesis of glycoproteins. | |
| mannosyl-oligosaccharide 1,3-1,6-α-mannosidase | Involved in the synthesis of glycoproteins. Group: Enzymes. Synonyms: mannosidase II; exo-1,3-1,6-α-mannosidase; α-D-mannosidase II; α-mannosidase II; α1-3,6-mannosidase; GlcNAc transferase I-dependent α1,3[α1,6]mannosidase; Golgi α-mannosidase II; ManII; 1,3(1,6)-α-D-mannosidase; 1,3-(1,6-)mannosyl-oligosaccharide α-D-mannohydrolase. Enzyme Commission Number: EC 3.2.1.114. CAS No. 82047-77-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3797; mannosyl-oligosaccharide 1,3-1,6-α-mannosidase; EC 3.2.1.114; 82047-77-6; mannosidase II; exo-1,3-1,6-α-mannosidase; α-D-mannosidase II; α-mannosidase II; α1-3,6-mannosidase; GlcNAc transferase I-dependent α1,3[α1,6]mannosidase; Golgi α-mannosidase II; ManII; 1,3(1,6)-α-D-mannosidase; 1,3-(1,6-)mannosyl-oligosaccharide α-D-mannohydrolase. Cat No: EXWM-3797. | |
| mannosyl-oligosaccharide glucosidase | Also acts, more slowly, on the corresponding glycolipids and glycopeptides. Involved in the formation of high-mannose and complex glycoproteins. Group: Enzymes. Synonyms: Glc3Man9NAc2 oligosaccharide glucosidase; trimming glucosidase I. Enzyme Commission Number: EC 3.2.1.106. CAS No. 78413-07-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3789; mannosyl-oligosaccharide glucosidase; EC 3.2.1.106; 78413-07-7; Glc3Man9NAc2 oligosaccharide glucosidase; trimming glucosidase I. Cat No: EXWM-3789. | |
| mannotetraose 2-α-N-acetylglucosaminyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.138. CAS No. 81032-47-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2363; mannotetraose 2-α-N-acetylglucosaminyltransferase; EC 2.4.1.138; 81032-47-5; α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2363. | |
| mannuronan 5-epimerase | The enzyme epimerizes the C-5 bond in some β-D-mannuronate residues in mannuronan, converting them to α-L-guluronate residues, and thus modifying the mannuronan into alginate. It is found in brown algae and alginate-producing bacterial species from the Pseudomonas and Azotobacter genera. Group: Enzymes. Synonyms: algG (gene name); alginate epimerase; C5-mannuronan epimerase; mannuronan C-5-epimerase. Enzyme Commission Number: EC 5.1.3.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5424; mannuronan 5-epimerase; EC 5.1.3.37; algG (gene name); alginate epimerase; C5-mannuronan epimerase; mannuronan C-5-epimerase. Cat No: EXWM-5424. | |
| mannuronan synthase | The enzyme catalyses the polymerization of β-D-mannuronate residues into a mannuronan polymer, an intermediate in the biosynthesis of alginate. It is found in brown algae and in alginate-producing bacterial species from the Pseudomonas and Azotobacter genera. Group: Enzymes. Synonyms: mannuronosyl transferase; alginate synthase (incorrect); alg8 (gene name); alg44 (gene name); GDP-D-mannuronate:alginate D-mannuronyltransferase. Enzyme Commission Number: EC 2.4.1.33. CAS No. 37257-31-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2567; mannuronan synthase; EC 2.4.1.33; 37257-31-1; mannuronosyl transferase; alginate synthase (incorrect); alg8 (gene name); alg44 (gene name); GDP-D-mannuronate:alginate D-mannuronyltransferase. Cat No: EXWM-2567. | |
| mannuronate reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannonate:NAD(P)+ 6-oxidoreductase. Other names in common use include mannonate dehydrogenase, mannonate (nicotinamide adenine dinucleotide, (phosphate))dehydrogenase, mannonate dehydrogenase, mannuronate reductase, mannonate dehydrogenase (NAD(P)+), D-mannonate:nicotinamide adenine dinucleotide (phosphate, and oxidoreductase (D-mannuronate-forming)). Group: Enzymes. Synonyms: mannonate dehydrogenase; mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase; mannonate dehydrogenase; mannuronate reductase; mannonate dehydrogenase (NAD(P)+); D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate. Enzyme Commission Number: EC 1.1.1.131. CAS No. 37250-62-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0035; mannuronate reductase; EC 1.1.1.131; 37250-62-7; mannonate dehydrogenase; mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase; mannonate dehydrogenase; mannuronate reductase; mannonate dehydrogenase (NAD(P)+); D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming)). Cat No: EXWM-0035. | |
| mannuronate-specific alginate lyase | The enzyme catalyses the degradation of alginate by a β-elimination reaction. It cleaves the (1?4) bond between β-D-mannuronate and either α-L-guluronate or β-D-mannuronate, generating oligosaccharides with 4-deoxy-α-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and β-D-mannuronate at the reducing end. Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to four residues, with preference for shorter products. cf. EC 4.2.2.11, guluronate-specific alginate lyase. Group: Enzymes. Synonyms: alginate lyase I; alginate lyase; alginase I; alginase II; alginase; poly(β-D-1,4-mannuronide) lyase; poly(β-D-mannuronate) lyase; aly (gene name) (ambiguous); poly[(1?4)-β-D-mannuronide] lyase. Enzyme Commission Number: EC 4.2.2.3. CAS No. 9024-15-1. Alginate lyase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5103; mannuronate-specific alginate lyase; EC 4.2.2.3; 9024-15-1; alginate lyase I; alginate lyase; alginase I; alginase II; alginase; poly(β-D-1,4-mannuronide) lyase; poly(β-D-mannuronate) lyase; aly (gene name) (ambiguous); poly[(1?4)-β-D-mannuronide] lyase. Cat No: EXWM-5103. | |
| Manogepix | Manogepix (E1210) is a first-in-class, broad-spectrum and orally active antifungal. Manogepix has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E1210; APX001A. CAS No. 936339-60-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18233. |  |
| Manool | Manool is a diterpene from Salvia officinalis. Manool induces selective cytotoxicity in cancer cells. Manool arrests the cancer cells at the G(2)/M phase of the cell cycle[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 596-85-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N1039A. | |
| MANS peptide | MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 479482-23-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10218. | |
| Manumycin | It is produced by the strain of Str. parvullus ETH 25000. It has anti-gram-positive bacterial effect, and has weak antibacterial effect on some mycobacteria and candida. Synonyms: Manumycin A; NSC 622141; Antibiotic UCF 1C; 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-; (-)-Manumycin A; Antibiotic TMC 1F. Grade: ≥98%. CAS No. 52665-74-4. Molecular formula: C31H38N2O7. Mole weight: 550.64. | |
| Manumycin A | Antibiotic. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50= 30nM). Does not affect geranyl geranyl transferase (IC50=180uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Neutral sphingomyelinase inhibitor. Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Manumycin A | Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF α, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion[1][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52665-74-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6796. | |
| Manumycin A (NSC-622141, UFC 1C) | An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50 = 30nM). Does not affect geranyl geranyl transferase (GGTase) (IC50 = 180uM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM).uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Manumycin B | Antibiotic and antibacterial. Active against Gram-positive bacteria. Rasfarnesyltransferase and apoptosis (Caspase-1) inhibitor. AChE inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 139023-58-8. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| Manumycin E | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin E; 2,4,6-Undecatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-10-methyl-, (2E,4E,6E)-. CAS No. 156250-43-0. Molecular formula: C30H34N2O7. Mole weight: 534.61. | |
| Manumycin F | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin; asukamycin A1; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-. CAS No. 156317-47-4. Molecular formula: C31H34N2O7. Mole weight: 546.62. | |
| Manumycin G | It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: 2,4,6-Nonatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, (2E,4E,6E)-; 2,4,6-Nonatrienamide, N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, [1S-[1a,3(2E,4E,6E),5b,5(1E,3E,5E),6a]]-. Grade: ≥95%. CAS No. 156250-44-1. Molecular formula: C28H30N2O7. Mole weight: 506.55. | |
| Manzamine a | Manzamine a. Alternative Names: Keramamine A. CAS No. 104196-68-1. Purity: 95%+. Product ID: ACM104196681. Molecular formula: C36H44N4O. Mole weight: 548.8. IUPAC Name: (1R,2R,4R,5Z,12R,13S,16Z)-25-(9H-Pyrido[3,4-b]indol-1-yl)-11,22-diazapentacyclo[11.11.2.12,22.02,12.04,11]heptacosa-5,16,25-trien-13-ol. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Manzamine A hydrochloride | Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Keramamine A hydrochloride. CAS No. 104264-80-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117025A. | |
| Manzanate | Manzanate (Ethyl 2-Methyl Pentanoate). CAS No. 39255-32-8. FEMA No. 3488. VIGON Item # 503237. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| MAO-B-IN-55 | MAO-B-IN-55 (Compound 5c) is a reversible competitive MAO-B inhibitor with an IC50 of 2.9 nM, and it exhibits approximately 2750-fold higher selectivity for MAO-B over MAO-A. MAO-B-IN-55 can be used for the research of Parkinson's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1458219-02-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114620. | |
| Maoecrystal A | Maoecrystal A. Group: Biochemicals. Grades: Plant Grade. CAS No. 96850-30-5. Pack Sizes: 10mg. Molecular Formula: C22H28O6, Molecular Weight: 388.45. US Biological Life Sciences. | Worldwide |
| MAO-IN-M30 dihydrochloride | MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC50=37 nM) and MAO-B (IC50=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease[1][2][3]. MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 64821-19-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131036. | |
| MAP | Multiple Antigenic peptides (MAPs) are artificially branched peptides with lysine residues as the scaffold core, supporting the formation ≤8 branches with varying or the same peptide sequences. MAPs have been used to produce antibodies for immunological research. MAPs have a high molar ratio of peptide antigen to core molecule and does not require carrier protein to elicit antibody response. Synonyms: H-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-His-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Leu-Ala-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-Lys-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Leu-Ala-OH. Grade: >98%. Molecular formula: C180H331N47O37. Mole weight: 3745.92. | |
| MAP2 Antibody [G20G3] | MAP2,MAP-2,Microtubule-Associated Protein 2 (MAP2). Group: Antibodies. Alternative Names: MAP2,Microtubule-Associated Protein 2. Pack Sizes: 20ul. Product ID: F0548. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| MAP4 | MAP4. Group: Biochemicals. Grades: Purified. CAS No. 157381-42-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MAP4343 | MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 511-26-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107116. | |
| Mapatumumab | Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody. CAS No. 658052-09-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99265. | |
| MA-PEG4-vc-PAB-DMEA-duocarmycin DM | MA-PEG4-vc-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Synonyms: Mal-PEG4-vc-PAB-DMEA-duocarmycin DM. Grade: 95%. Molecular formula: C68H89ClN12O17. Mole weight: 1381.98. | |
| MA-PEG4-vc-PAB-DMEA-duocarmycin SA | MA-PEG4-vc-PAB-DMEA-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MA-PEG4-vc-PAB-DMEA. Synonyms: Mal-PEG4-vc-PAB-DMEA-duocarmycin SA. Grade: 95%. Molecular formula: C67H87ClN12O21. Mole weight: 1431.94. | |
| Mapenterol-[d11] hydrochloride | Mapenterol-[d11] hydrochloride is the labelled analogue of Mapenterol hydrochloride, which is a related drug of Clenbuterol. Synonyms: 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-(1,1-dimethyl-D6-propyl-D5-amino)-ethanol hydrochloride; Mapenterol-D11 hydrochloride; 4-Amino-3-chloro-α-[[(1,1-dimethylpropyl-d11)amino]methyl]-5-(trifluoromethyl)benzenemethanol Hydrochloride; Mapenterol-(dimethyl-d6, propyl-d5) hydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1325559-18-9. Molecular formula: C14H9D11ClF3N2O.HCl. Mole weight: 372.30. | |
| Mapenterol hydrochloride | Mapenterol hydrochloride. Group: Biochemicals. Alternative Names: 4-Amino-3-chloro-a-[[ (1, 1-dimethylpropyl) amino]methyl]-5- (trifluoromethyl) benzenemethanol. Grades: Highly Purified. CAS No. 54238-51-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C14H21Cl2F3N2O. US Biological Life Sciences. | Worldwide |
| MAPK13-IN-1 | MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 229002-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18850. | |
| MAP Kinase Kinase 3,6 (MKK3,6) Control Cell Extracts | MAP Kinase Kinase 3,6 (MKK3,6) Control Cell Extracts. Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences. | Worldwide |
| MAP Kinase Kinase 3,6 (MKK3,6) Nonphosphorylated Control Cell Extract | Nonphosphorylated Control Cell Extract for M2363-15A. Total cell extracts from NIH/3T3 cells, prepared without treatment, serve as a negative control. Group: Molecular Biology. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| MAP Kinase Kinase 3,6 (MKK3,6) Phosphorylated Control Cell Extract | MAP Kinase Kinase 3,6 (MKK3,6) Phosphorylated Control Cell Extract. Group: Molecular Biology. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| MAP Kinase Kinase 3,6 (MKK3,6) (Ser189/207) BioAssay Phosphorylation Detection Kit, Biotin (HRP) | MAP Kinase Kinase 3,6 (MKK3,6) (Ser189/207) BioAssay Phosphorylation Detection Kit, Biotin (HRP). Group: Molecular Biology. Grades: Affinity Purified. Pack Sizes: 100ul. US Biological Life Sciences. | Worldwide |
| MAP Kinase Kinase 3,6 (MKK3,6) (Ser189/207) BioAssay Phosphorylation Detection Kit, MAP Kinase Kinase 3,6 (MKK3,6) Nonphosphorylated Control Cell Extract | Nonphosphorylated Control Cell Extract for M2363-15A. Total cell extracts from NIH/3T3 cells, prepared without treatment, serve as a negative control. Group: Molecular Biology. Pack Sizes: 80ul. US Biological Life Sciences. | Worldwide |
| MAP Kinase Kinase 3,6 (MKK3,6) (Ser189/207) BioAssay Phosphorylation Detection Kit, MAP Kinase Kinase 3,6 (MKK3,6) Phosphorylated Control Cell Extract | Phosphorylated Control Cell Extract for M2363-15A. Total cell extracts from NIH/3T3 cells, prepared with UV light treatment, serve as a positive control. Group: Molecular Biology. Pack Sizes: 80ul. US Biological Life Sciences. | Worldwide |
| MAP Kinase, N-terminal histidine-tagged non-activated protein from rat | MAP Kinase, N-terminal histidine-tagged non-activated protein from rat. Uses: For analytical and research use. CAS No. 137632-08-7. Catalog: AP137632087. |  |
| MAP Kinase p38, Control Cell Extracts (Mitogen Activated Protein Kinase p38, MAPK p38) | P38 MAP kinase (MAPK), also called RK (3) or CSBP (2), is the mammalian homologue of the yeast HOG kinase and participates in a signaling cascade controlling cellular responses to cytokines and stress (1-4). Four isoforms of p38 MAP kinase, alpha, beta, gamma and delta, have been identified so far. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-5). MKK3 and SEK activate p38 MAP kinase by phosphorylation at threonine 180 and tyrosine 182. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase 2 (3) and to phosphorylate the transcription factors ATF-2 (5), Max (6) and MEF2 (5-8). Nonphosphorylated p38 MAP Kinase Control Cell. Group: Biologicals. Alternative Names: EC=2.7.11.24. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences. | Worldwide |
| MAPK Inhibitor Library | A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include ERK, JNK, MEK, p38, MAPK, Raf, RSK, MNK, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1400. Categories: MAPK Inhibitor Libraries. |  |
| MAP (KLAL) | MAP (KLAL) is an amphipathic α-helical cell-penetrating peptide (CPP). CPP can bind macromolecules and be used as a drug delivery vehicle. Synonyms: H-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-Lys-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Leu-Ala-OH; L-lysyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-L-leucyl-L-lysyl-L-leucyl-L-alanine. Grade: ≥95%. Molecular formula: C90H169N23O19. Mole weight: 1877.48. | |
| MAPK/MAK/MRK overlapping kinase (11-20) | MAPK/MAK/MRK overlapping kinase (11-20) is a 10-aa peptide. MAPK/MAK/MRK overlapping kinase is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. | |
| MAPK/MAK/MRK overlapping kinase (32-40) | MAPK/MAK/MRK overlapping kinase (32-40) is a 9-aa peptide. MAPK/MAK/MRK overlapping kinase is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. | |
| MAPK/MAK/MRK overlapping kinase (352-360) | MAPK/MAK/MRK overlapping kinase (352-360) is a 9-aa peptide. MAPK/MAK/MRK overlapping kinase is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. | |
| Maple Furanone | Maple Furanone (5-Ethyl 3-Hydroxy 4-Methyl Furanone). CAS No. 698-10-2. FEMA No. 3153. Kosher: Y. VIGON Item # 501331. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Maple Furanone 50% in Triethyl Citrate | Maple Furanone 50% in Triethyl Citrate. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508175. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Maple Furanone Natural | Maple Furanone Natural. CAS No. 698-10-2. FEMA No. 3153. Kosher: Y. VIGON Item # 507999. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Maple Furanone Natural 10% in Triacetin | Maple Furanone Natural 10% in Triacetin. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508378. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. | America & Internationally |
| Maple Furanone Natural 1% in PG | Maple Furanone Natural 1% in PG. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508000. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Maple Lactone | Maple Lactone (Methyl Cyclopentenolone). CAS No. 765-70-8. FEMA No. 2700. Kosher: Y. VIGON Item # 500242. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Maplirpacept | Maplirpacept (TTI-622; PF-07901801) is a fusion protein consisting of the CD47-binding domain of human SIRPα linked to the Fc region of human IgG4. Maplirpacept enhances phagocytosis by blocking CD47[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TTI-622; PF-07901801. CAS No. 2631667-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990707. | |
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