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Mannosylglycerate synthase from Rhodothermus marinus, Recombinant
Mannosylglycerate synthase (EC 2.4.1.269) is an enzyme with system name GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase. This enzyme catalyses the following chemical reaction: GDP-mannose + D-glycerate <-> GDP + 2-O-(alpha-D-mannopyranosyl) -D-glycerate. Depending on conditions mannosylglycerate synthase is more or less specific for the GDP-mannose and D-glycerate. Group: Enzymes. Synonyms: GDP-Man:mannosylglycerate synthase; α-mannosyltransferase; GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase. Enzyme Commission Number: EC 2.4.1.-. Purity: > 95 % as judged by SDS-PAGE. Mannosylglycerate synthase. Mole weight: 47190.6 Da. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Rhodothermus marinus DSM 4252. GDP-Man:mannosylglycerate synthase; α-mannosyltransferase; GDP-mannose:D-glycerate 2-alpha-D-mannosyltransferase; Mannosylglycerate synthase; EC 2.4.1.-. Cat No: NATE-1216.
mannosylglycoprotein endo-β-mannosidase
The substrate group is a substituent on N-4 of an asparagine residue in the glycoprotein. The mannose residue at the non-reducing end of the sequence may carry further α-D-mannosyl groups on O-3 or O-6, but such a substituent on O-3 of the β-D-mannosyl group prevents the action of the enzyme. The enzyme was obtained from the lily, Lilium longiflorum. Group: Enzymes. Synonyms: endo-β-mannosidase. Enzyme Commission Number: EC 3.2.1.152. CAS No. 141176-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3835; mannosylglycoprotein endo-β-mannosidase; EC 3.2.1.152; 141176-95-6; endo-β-mannosidase. Cat No: EXWM-3835.
A group of related enzymes. Group: Enzymes. Synonyms: N,N'-diacetylchitobiosyl β-N-acetylglucosaminidase; endo-β-N-acetylglucosaminidase; mannosyl-glycoprotein endo-β-N-acetylglucosamidase; di-N-acetylchitobiosyl β-N-acetylglucosaminidase; endo-β. Enzyme Commission Number: EC 3.2.1.96. CAS No. 37278-88-9. Endo-β-N-acetylglucosaminidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3959; mannosyl-glycoprotein endo-β-N-acetylglucosaminidase; EC 3.2.1.96; 37278-88-9; N,N'-diacetylchitobiosyl β-N-acetylglucosaminidase; endo-β-N-acetylglucosaminidase; mannosyl-glycoprotein endo-β-N-acetylglucosamidase; di-N-acetylchitobiosyl β-N-acetylglucosaminidase; endo-β-acetylglucosaminidase; endo-β-(1?4)-N-acetylglucosaminidase; mannosyl-glycoprotein 1,4-N-acetamidodeoxy-β-D-glycohydrolase; endoglycosidase S; endo-N-acetyl-β-D-glucosaminidase; endo-N-acetyl-β-glucosaminidase; endo-β-N-acetylglucosaminidase D; endo-β-N-acetylglucosaminidase F; endo-β-N-acetylglucosaminidase H; endo-β-N-acetylglucosaminidase L; glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-β-glucosaminohydrolase; endoglycosidase H. Cat No: EXWM-3959.
mannosyl-oligosaccharide 1,2-α-mannosidase
Involved in the synthesis of glycoproteins. Group: Enzymes. Synonyms: mannosidase 1A; mannosidase 1B; 1,2-α-mannosidase; exo-α-1,2-mannanase; mannose-9 processing α-mannosidase; glycoprotein processing mannosidase I; mannosidase I; Man9-mannosidase; ManI; 1,2-α-mannosyl-oligosaccharide α-D-mannohydrolase. Enzyme Commission Number: EC 3.2.1.113. CAS No. 9068-25-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3796; mannosyl-oligosaccharide 1,2-α-mannosidase; EC 3.2.1.113; 9068-25-1; mannosidase 1A; mannosidase 1B; 1,2-α-mannosidase; exo-α-1,2-mannanase; mannose-9 processing α-mannosidase; glycoprotein processing mannosidase I; mannosidase I; Man9-mannosidase; ManI; 1,2-α-mannosyl-oligosaccharide α-D-mannohydrolase. Cat No: EXWM-3796.
mannosyl-oligosaccharide 1,3-1,6-α-mannosidase
Involved in the synthesis of glycoproteins. Group: Enzymes. Synonyms: mannosidase II; exo-1,3-1,6-α-mannosidase; α-D-mannosidase II; α-mannosidase II; α1-3,6-mannosidase; GlcNAc transferase I-dependent α1,3[α1,6]mannosidase; Golgi α-mannosidase II; ManII; 1,3(1,6)-α-D-mannosidase; 1,3-(1,6-)mannosyl-oligosaccharide α-D-mannohydrolase. Enzyme Commission Number: EC 3.2.1.114. CAS No. 82047-77-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3797; mannosyl-oligosaccharide 1,3-1,6-α-mannosidase; EC 3.2.1.114; 82047-77-6; mannosidase II; exo-1,3-1,6-α-mannosidase; α-D-mannosidase II; α-mannosidase II; α1-3,6-mannosidase; GlcNAc transferase I-dependent α1,3[α1,6]mannosidase; Golgi α-mannosidase II; ManII; 1,3(1,6)-α-D-mannosidase; 1,3-(1,6-)mannosyl-oligosaccharide α-D-mannohydrolase. Cat No: EXWM-3797.
mannosyl-oligosaccharide glucosidase
Also acts, more slowly, on the corresponding glycolipids and glycopeptides. Involved in the formation of high-mannose and complex glycoproteins. Group: Enzymes. Synonyms: Glc3Man9NAc2 oligosaccharide glucosidase; trimming glucosidase I. Enzyme Commission Number: EC 3.2.1.106. CAS No. 78413-07-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3789; mannosyl-oligosaccharide glucosidase; EC 3.2.1.106; 78413-07-7; Glc3Man9NAc2 oligosaccharide glucosidase; trimming glucosidase I. Cat No: EXWM-3789.
mannosyl-queuosine
Mannosyl-queuosine (manQ) is a non-canonical RNA nucleoside present in the anticodon loop of certain tRNAs. Synonyms: manQ; 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-3,7-dihydro-5-[[[(1S,4S,5R)-4-hydroxy-5-(β-D-mannopyranosyloxy)-2-cyclopenten-1-yl]amino]methyl]-7-β-D-ribofuranosyl-; O-5''-β-D-mannosylqueuosine; man Q nucleoside; beta-D-mannosylqueuosine; (1R,2S,5S)-2-({[2-Amino-4-oxo-7-(β-D-ribofuranosyl)-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]methyl}amino)-5-hydroxy-3-cyclopenten-1-yl β-D-mannopyranoside. Grades: ≥95%. CAS No. 60398-20-1. Molecular formula: C23H33N5O12. Mole weight: 571.54.
Mannotetraose
Mannotetraose is a versatile carbohydrate compound, renowned for its potent immunostimulator and immunomodulator attributes. Furthermore, Mannotetraose exhibits promising prospects in revolutionizing drug delivery systems and facilitating the development of superior formulation. Synonyms: 1,3-α-1,6-α-D-Mannotetraose; α-D-Mannopyranosyl-(1->3)-[α-D-mannopyranosyl-(1->6)]-α-D-mannopyranosyl-(1->6)-D-mannopyranose; Manalpha1-3(Manalpha1-6)Manalpha1-6Man; alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-D-Man; alpha-D-mannopyranosyl-(1->3)-[alpha-D-mannopyranosyl-(1->6)]-alpha-D-mannopyranosyl-(1->6)-D-mannopyranose. Grades: ≥98%. Molecular formula: C24H42O21. Mole weight: 666.58.
mannotetraose 2-α-N-acetylglucosaminyltransferase
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.138. CAS No. 81032-47-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2363; mannotetraose 2-α-N-acetylglucosaminyltransferase; EC 2.4.1.138; 81032-47-5; α-N-acetylglucosaminyltransferase; uridine diphosphoacetylglucosamine mannoside α1?2-αcetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:mannotetraose α-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2363.
Mannotetraose squarate
Mannotetraose squarate is an innovative biomedical compound, aiding in studying multifarious bacterial afflictions encompassing urinary tract ailments, respiratory pathologies and dermal maladies. Synonyms: 4-[[2-[[3- ([O-b-D-Mannopyranosyl- (1?2) -O-b-Dmannopyranosyl- (1?2) -O-b-D-mannopyranosyl- (1?2) -b-D-mannopyranosyl]oxy) propyl]thio]ethyl]amino]-3-ethoxy-3-cyclobutene-1, 2-dione. CAS No. 385842-90-0. Molecular formula: C35H57NO24S. Mole weight: 907.89.
mannuronan 5-epimerase
The enzyme epimerizes the C-5 bond in some β-D-mannuronate residues in mannuronan, converting them to α-L-guluronate residues, and thus modifying the mannuronan into alginate. It is found in brown algae and alginate-producing bacterial species from the Pseudomonas and Azotobacter genera. Group: Enzymes. Synonyms: algG (gene name); alginate epimerase; C5-mannuronan epimerase; mannuronan C-5-epimerase. Enzyme Commission Number: EC 5.1.3.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5424; mannuronan 5-epimerase; EC 5.1.3.37; algG (gene name); alginate epimerase; C5-mannuronan epimerase; mannuronan C-5-epimerase. Cat No: EXWM-5424.
mannuronan synthase
The enzyme catalyses the polymerization of β-D-mannuronate residues into a mannuronan polymer, an intermediate in the biosynthesis of alginate. It is found in brown algae and in alginate-producing bacterial species from the Pseudomonas and Azotobacter genera. Group: Enzymes. Synonyms: mannuronosyl transferase; alginate synthase (incorrect); alg8 (gene name); alg44 (gene name); GDP-D-mannuronate:alginate D-mannuronyltransferase. Enzyme Commission Number: EC 2.4.1.33. CAS No. 37257-31-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2567; mannuronan synthase; EC 2.4.1.33; 37257-31-1; mannuronosyl transferase; alginate synthase (incorrect); alg8 (gene name); alg44 (gene name); GDP-D-mannuronate:alginate D-mannuronyltransferase. Cat No: EXWM-2567.
mannuronate reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannonate:NAD(P)+ 6-oxidoreductase. Other names in common use include mannonate dehydrogenase, mannonate (nicotinamide adenine dinucleotide, (phosphate))dehydrogenase, mannonate dehydrogenase, mannuronate reductase, mannonate dehydrogenase (NAD(P)+), D-mannonate:nicotinamide adenine dinucleotide (phosphate, and oxidoreductase (D-mannuronate-forming)). Group: Enzymes. Synonyms: mannonate dehydrogenase; mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase; mannonate dehydrogenase; mannuronate reductase; mannonate dehydrogenase (NAD(P)+); D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate. Enzyme Commission Number: EC 1.1.1.131. CAS No. 37250-62-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0035; mannuronate reductase; EC 1.1.1.131; 37250-62-7; mannonate dehydrogenase; mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase; mannonate dehydrogenase; mannuronate reductase; mannonate dehydrogenase (NAD(P)+); D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming)). Cat No: EXWM-0035.
mannuronate-specific alginate lyase
The enzyme catalyses the degradation of alginate by a β-elimination reaction. It cleaves the (1?4) bond between β-D-mannuronate and either α-L-guluronate or β-D-mannuronate, generating oligosaccharides with 4-deoxy-α-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and β-D-mannuronate at the reducing end. Depending on the composition of the substrate, the enzyme produces oligosaccharides ranging from two to four residues, with preference for shorter products. cf. EC 4.2.2.11, guluronate-specific alginate lyase. Group: Enzymes. Synonyms: alginate lyase I; alginate lyase; alginase I; alginase II; alginase; poly(β-D-1,4-mannuronide) lyase; poly(β-D-mannuronate) lyase; aly (gene name) (ambiguous); poly[(1?4)-β-D-mannuronide] lyase. Enzyme Commission Number: EC 4.2.2.3. CAS No. 9024-15-1. Alginate lyase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5103; mannuronate-specific alginate lyase; EC 4.2.2.3; 9024-15-1; alginate lyase I; alginate lyase; alginase I; alginase II; alginase; poly(β-D-1,4-mannuronide) lyase; poly(β-D-mannuronate) lyase; aly (gene name) (ambiguous); poly[(1?4)-β-D-mannuronide] lyase. Cat No: EXWM-5103.
Manoalide
Heterocyclic Organic Compound. CAS No. 075088-80-1. Purity: N/A. Catalog: ACM075088801.
Manogepix
Manogepix (E1210) is a first-in-class, broad-spectrum and orally active antifungal. Manogepix has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E1210; APX001A. CAS No. 936339-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18233.
MANS peptide
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate ( MARCKS ), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis [1]. Uses: Scientific research. Group: Peptides. CAS No. 479482-23-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10218.
MANT-5'-dAMP
MANT-5'-dAMP is a fluorescent analogue of 2'-deoxyadenosine-5'-monophosphate (λexc350 nm, λem446 nm), which is used for research into 5'-dAMP-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- Deoxy- 3'- O- (N'- Methylanthraniloyl)adenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. Molecular formula: C18H21N6O7P (free acid). Mole weight: 464.4 (free acid).
MANT-5'-dGMP
MANT-5'-dGMP is a fluorescent analogue of 2'-deoxyguanosine-5'-monophosphate (λexc350 nm, λem442 nm), which is used for research into 5'-dGMP-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- monophosphate. Grades: ≥ 97 % by HPLC. Molecular formula: C18H21N6O8P (free acid). Mole weight: 480.4 (free acid).
MANT-5'-IMP
MANT-5'-IMP is a fluorescent analogue of inosine-5'-monophosphate (λexc355 nm, λem448 nm). The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'- / 3'- O- (N'- Methylanthraniloyl)inosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C18H20N5O9P (free acid). Mole weight: 481.4 (free acid).
Mant-ADP
Mant-ADP is an extensively employed biochemical compound within the biomedical industry, serving as a pivotal substrate for an array of enzymes implicated in nucleotide metabolism. Its significance lies in its profound contribution to the exploration of enzyme kinetics and regulation associated with energy metabolism, encompassing afflictions like mitochondrial disorders and metabolic syndromes. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 151481-85-5. Molecular formula: C18H22N6O11P2(free acid). Mole weight: 560.35 (free acid).
Mant-AMP
Mant-AMP is a vital tool in the biomedical industry used for adenosine monophosphate (AMP) analysis. This product allows for the identification and quantification of AMP is a key nucleotide involved in numerous cellular processes. Its applications range from studying energy metabolism and signal transduction pathways to investigating diseases associated with AMP dysregulation, such as metabolic disorders and cancer. Synonyms: 2'/3'-(N-Methyl-anthraniloyl)-adenosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N6O8P (free acid). Mole weight: 480.37 (free acid).
MANT-Ap4A
MANT-Ap4A is a fluorescent analogue of P1,P4-Di-(adenosine-5')-tetraphosphate (λexc357 nm; λem446 nm), which can be used for research into polyphosphate-dependent receptor proteins. The MANT fluorophore is sensitive for its environment and can change its spectral properties while binding. Synonyms: P1- (5'- [2'- / 3'- O- (N'- Methylanthraniloyl)adenosyl])- P4- (5'- adenosyl)- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 877666-36-9. Molecular formula: C28H35N11O20P4 (free acid). Mole weight: 969.5 (free acid).
MANT-Ap4-MANT-A
MANT-Ap4-MANT-A is a fluorescent analogue of P1,P4-Di-(adenosine-5')-tetraphosphate (λexc~357 nm; λem~446 nm), which is used in studies related to polyphosphate-dependent receptor proteins. For the sensitivity of the MANT fluorophore to its environment, it is often used in spectrum to study interactions of proteins. Synonyms: P1- (5'- [2'- / 3'- O- (N'- Methylanthraniloyl)adenosyl])- P4- (5'- [2'- / 3'- O- (N'- methylanthraniloyl)adenosyl])- tetraphosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H42N12O21P4 (free acid). Mole weight: 1102.7 (free acid).
Mant-AppNHp
Mant-AppNHp, a remarkable biomedical compound, used in expediting investigations concerning enzyme kinetics while unraveling the complexities encompassing guanine nucleotide-binding proteins. Synonyms: (Mant-AMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-[(β,γ )-imido] triphosphate,Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 85287-56-6. Molecular formula: C18H24N7O13P3(free acid). Mole weight: 639.34 (free acid).
Mant-ATP
Mant-ATP is a key compound widely used in biochemical research and drug discovery acting as a fluorescent probe for investigating enzymatic activities and ATP-dependent cellular processes. Mant-ATP is used in the study of various diseases like cancer, diabetes and neurodegenerative disorders. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 151481-86-6. Molecular formula: C18H23N6O14P3(free acid). Mole weight: 640.33 (free acid).
Mant-ATPγS
Mant-ATPγS is a valuable research tool used in the biomedical industry. It is a nucleotide analog and non-hydrolyzable mimic of ATP, often employed in studies related to G protein-coupled receptor signaling pathways. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-adenosine-5'-( γ -thio)-triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H23N6O13P3S (free acid). Mole weight: 656.39 (free acid).
Mant-cAMP
Mant-cAMP is a biochemical compound commonly used in biomedicine for research purposes. It is a stable analog of cyclic adenosine monophosphate (cAMP). Researchers utilize Mant-cAMP to study cellular signaling pathways, particularly those involving cAMP-dependent processes. Its applications range from investigating drug targets and receptor interactions to examining the effects of cAMP on various diseases, such as cancer and cardiovascular disorders. Synonyms: 2'-O-(N-Methyl-anthraniloyl)-adenosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 83707-14-6. Molecular formula: C18H19N6O7P (free acid). Mole weight: 462.35 (free acid).
MANT-cCMP
MANT-cCMP is a fluorescent cCMP analogue with λexc350 nm and λem441 nm, which is potentially used for phosphodiesterase studies. Synonyms: 2'-O-(N'-Methylanthraniloyl)cytidine-3',5'-cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 1477570-24-3. Molecular formula: C17H18N4NaO8P. Mole weight: 460.3.
MANT-c-diAMP
MANT-c-diAMP is a fluorescent analogue of c-diAMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-O-(N'-Methylanthraniloyl)-cyclic diadenosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C28H31N11O13P2 (free acid). Mole weight: 791.6 (free acid).
MANT-c-diGMP
MANT-c-diGMP is a fluorescent analogue of c-diGMP, the bacterial second messenger. The MANT fluorophore (λexc355 nm; λem448 nm) is sensitive for its environment and can change its spectral properties while binding. Synonyms: 2'-O-(N'-Methylanthraniloyl)-cyclic diguanosine monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1384529-33-2. Molecular formula: C28H31N11O15P2 (free acid). Mole weight: 823.6 (free acid).
Mant-cGMP
Mant-cGMP is a crucial tool extensively utilized in biomedical research. It serves as a fluorescent probe for studying guanine nucleotide exchange reactions and has a wide range of applications. Mant-cGMP enables the investigation of cyclic guanosine monophosphate (cGMP)-dependent physiological and pathological processes, including drug discovery and the treatment of cardiovascular diseases and pulmonary hypertension. Synonyms: 2'-O-(N-Methyl-anthraniloyl)-guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 98 % by HPLC. CAS No. 83707-15-7. Molecular formula: C18H19N6O8P (free acid). Mole weight: 478.35 (free acid).
Mant-dADP
Mant-dADP is a fluorescent analog of adenosine 5'-diphosphate (ADP) commonly used in biomedical research. It is utilized to study ATP-binding proteins and their interactions, including G-proteins and kinases. Mant-dADP enables visualization and analysis of ADP-mediated signaling pathways, contributing to the understanding and research of various diseases associated with dysregulation of these pathways. Synonyms: 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyadenosine-5'-diphosphate, Triethylammonium salt; 2'-deoxy-3'-mant-ADP. Grades: ≥ 95 % by HPLC. CAS No. 91828-83-0. Molecular formula: C18H22N6O10P2(free acid). Mole weight: 544.35 (free acid).
Mant-dATP
Mant-dATP is a vital tool acting as a modified form of deoxyadenosine triphosphate (dATP) labeled with the mant fluorophore. Mant-dATP is beneficial for studying various enzymatic activities, including DNA polymerases, DNA ligases and helicases, due to its ability to monitor nucleotide incorporation during DNA synthesis. Additionally, it plays a crucial role in investigating diseases related to DNA replication and repair mechanisms. Synonyms: 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyadenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 128113-53-1. Molecular formula: C18H23N6O13P3(free acid). Mole weight: 624.33 (free acid).
Mant-dGDP
Mant-dGDP is a vital tool extensively used in biomedicine for studying G protein signaling pathways. It enables researchers to analyze the role and mechanism of G proteins in various biological processes. This product plays an indispensable role in investigating the impact of G protein dysregulation on diseases like cancer, cardiovascular disorders, and neurological abnormalities. Synonyms: 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 127383-33-9. Molecular formula: C18H22N6O11P2(free acid). Mole weight: 560.35 (free acid).
Mant-dGppNHp
Mant-dGppNHp is a nucleotide derivative used to scrutinize the intricate mechanisms underpinning G protein signaling cascades and their profound bearing on an extensive gamut of ailments ranging from malignancies to cardiovascular anomalies and neurological aberrations. Synonyms: (Mant-dGMPPNP); 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'- [(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 170032-90-3. Molecular formula: C18H24N7O13P3(free acid). Mole weight: 639.34 (free acid).
Mant-dGTP
Mant-dGTP is a modified nucleotide, emerging as an indispensable substrate for DNA polymerase reactions, particularly used in the realm of real-time PCR and DNA sequencing. Its unparalleled efficacy in facilitating the detection of DNA synthesis surpasses conventional nucleotides, lending itself to paramount importance in research encompassing genetic disorders, infectious diseases and cancer diagnostics. Synonyms: 3'-O-(N-Methyl-anthraniloyl)-2'-deoxyguanosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 124615-99-2. Molecular formula: C18H23N6O14P3(free acid). Mole weight: 640.33 (free acid).
Mant-GDP
Mant-GDP, a fluorescent analogue of 5'-GDP (λexc 350 nm; λem 442 nm), is useful for research into GDP-dependent receptor proteins. MANT fluorescence is sensitive to the environment of the fluorophore. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 148821-02-7. Molecular formula: C18H22N6O12P2(free acid). Mole weight: 576.35 (free acid).
Mant-GMP
Mant-GMP, a fluorescent nucleotide analog, is extensively utilized in the biochemical and biomedical realms for several purposes, such as labeling, sequencing, and detection, owing to its proficiency in integrating within DNA and RNA. In tandem with its efficacy in studying enzymes involved in DNA and RNA metabolism, it has also been employed in the development of novel cancer and viral infection therapeutics. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-monophosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N6O9P (free acid). Mole weight: 496.37 (free acid).
Mant-GppCp
Mant-GppCp is an illustrious fluorescent nucleotide analog used in the profound examination of G protein-coupled receptor signaling pathways and protein interactions. By aptly studying the hydrolysis of guanosine triphosphate (GTP) by GTPases, Mant-GppCp embodies a pivotal role in comprehending and studying ailments intrinsically linked to the disruption of G protein signaling. Synonyms: (Mant-GMPPCP); 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-[(β,γ)-methyleno]triphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C19H25N6O14P3(free acid). Mole weight: 654.35 (free acid).
Mant-GppNHp
MANT-GppNHp bind to G alpha(I)-proteins with low affinity and are ineffective at activating G alpha. Besides, MANT-GppNHp constitutes a novel class of potent competitive AC inhibitors. Synonyms: (Mant-GMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 148821-01-6. Molecular formula: C18H24N7O14P3(free acid). Mole weight: 655.34 (free acid).
Mant-GTP
Mant-GTP, a fluorescent analogue of guanosine- 5'- triphosphate with Ex/Em = 355/448 nm, is useful for research into GTP-dependent receptor proteins. This highly environmental sensitive fluorescence of Mant makes Mant-GTP useful for directly detecting the nucleotide-protein interactions. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. CAS No. 148821-03-8. Molecular formula: C18H23N6O15P3(free acid). Mole weight: 656.33 (free acid).
Mant-GTPγS
Mant-GTPγS had lower affinities for Gαs and Gαi than GTPγS/GppNHp as assessed by inhibition of GTP hydrolysis of receptor-Gα fusion proteins. MANT-GTPγS was much less effective than GTPγS at disrupting the ternary complex between the formyl peptide receptor and Gαi2. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-(γ-thio)-triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 136749-24-1. Molecular formula: C18H23N6O14P3S (free acid). Mole weight: 672.39 (free acid).
Mant-ITPγS
Mant-ITPγS is a crucial fluorescent nucleotide analog used in biomedical research. With its ability to bind specifically to G-protein-coupled receptors, Mant-ITPγS helps in investigating receptor-ligand interactions. This product aids in studying various cellular responses related to drug discovery, cancer research and neurobiology. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-inosine-5'-(γ-thio)-triphosphate, Sodium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H22N5O14P3S (free acid). Mole weight: 657.37 (free acid).
Mant-N6-Methyl-ATP
Mant-N6-Methyl-ATP is a modified form of ATP that contains a mant (2'(3')-O-(N-Methylanthraniloyl)) group. This product is widely utilized in various biochemical and cellular studies, particularly in investigating the role and regulation of purinergic receptors and signaling pathways. With its unique properties, Mant-N6-Methyl-ATP aids in understanding diseases related to purinergic receptors, including inflammation, cardiovascular disorders and neurological conditions. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-N; -methyl-adenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C19H25N6O14P3(free acid). Mole weight: 654.36 (free acid).
Mant-XDP
Mant-XDP, a fluorescent probe, is a tool of promise utilized for monitoring MMPs' activity, enzymes that instigate tissue degradation underlying several diseases claiming countless lives. As a diagnostic tool, it shows sufficient prospects for use in conditions, ranging from cancer to rheumatoid arthritis, while simultaneously illuminating its potential therapeutic applications. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-diphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H21N5O13P2(free acid). Mole weight: 577.33 (free acid).
Mant-XppNHp
Mant-XppNHp is a crucial compound for studying G protein-coupled receptor (GPCR) signaling pathways. It is used to activate G proteins and mimic the action of GTP in order to investigate signal transduction mechanisms and drug discovery processes related to several diseases, such as cancer, cardiovascular disorders and neurological conditions. Synonyms: (Mant-XMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C18H23N6O15P3(free acid). Mole weight: 656.33 (free acid).
Mant-XTP
Mant-XTP is an interdisciplinary compound, used for studying an array of afflictions, encompassing cancerous anomalies and insidious viral invasions. This formidable inhibitor selectively engages pivotal molecular protagonists governing intricate cell proliferation dynamics and viral duplicative processes. Synonyms: 2'/3'-O-(N-Methyl-anthraniloyl)-xanthosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C18H22N5O16P3(free acid). Mole weight: 657.31 (free acid).
Manumycin
It is produced by the strain of Str. parvullus ETH 25000. It has anti-gram-positive bacterial effect, and has weak antibacterial effect on some mycobacteria and candida. Synonyms: Manumycin A; NSC 622141; Antibiotic UCF 1C; 2,4-Decadienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-2,4,6-trimethyl-, (2E,4E,6R)-; (-)-Manumycin A; Antibiotic TMC 1F. Grades: ≥98%. CAS No. 52665-74-4. Molecular formula: C31H38N2O7. Mole weight: 550.64.
Manumycin A
Antibiotic. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50= 30nM). Does not affect geranyl geranyl transferase (IC50=180uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Neutral sphingomyelinase inhibitor. Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Manumycin A (NSC-622141, UFC 1C)
An antibiotic Isolated from Streptomyces parvulus. A Potent, selective and competitive cell permeable rasfarnesyltransferase (FTase) inhibitor (IC50 = 30nM). Does not affect geranyl geranyl transferase (GGTase) (IC50 = 180uM). Blocks insulin-induced MAP kinase activation in rat cardiac myocytes (19uM).uM). Inhibition is competitive with respect to farnesyl pyrophosphate and non-competitive with respect to Ras. Group: Biochemicals. Grades: Highly Purified. CAS No. 52665-74-4. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Manumycin B
Antibiotic and antibacterial. Active against Gram-positive bacteria. Rasfarnesyltransferase and apoptosis (Caspase-1) inhibitor. AChE inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 139023-58-8. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
Worldwide
Manumycin E
It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin E; 2,4,6-Undecatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-10-methyl-, (2E,4E,6E)-. CAS No. 156250-43-0. Molecular formula: C30H34N2O7. Mole weight: 534.61.
Manumycin F
It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: Asukamycin; asukamycin A1; 2,4,6-Heptatrienamide, 7-cyclohexyl-N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-. CAS No. 156317-47-4. Molecular formula: C31H34N2O7. Mole weight: 546.62.
Manumycin G
It is produced by the strain of Str. sp. WB-83. It has anti-gram-positive bacteria and Escherichia coli effects, but the effect is very weak against other anti-gram-negative bacteria, and has no effect on fungi. It inhibits RAS Faraday base transfer with IC50 of 5 μmol/L. It has weak cytotoxic activity against human cloned cancer cell lines HCT-116 (IC50 is 15.6 μg/mL). Synonyms: 2,4,6-Nonatrienamide, N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, (2E,4E,6E)-; 2,4,6-Nonatrienamide, N-[5-hydroxy-5-[7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyl-, [1S-[1a,3(2E,4E,6E),5b,5(1E,3E,5E),6a]]-. Grades: ≥95%. CAS No. 156250-44-1. Molecular formula: C28H30N2O7. Mole weight: 506.55.
Manzamine a
Manzamine A is an orally active beta-carboline alkaloid. Group: Inhibitors. Alternative Names: Keramamine A. CAS No. 104196-68-1. Molecular formula: C36H44N4O. Mole weight: 548.8. Appearance: Yellow oil. Purity: 95%+. IUPACName: (1R, 2R, 4R, 5Z, 12R, 13S, 16Z)-25-(9H-Pyrido[3, 4-b]indol-1-yl)-11, 22-diazapentacyclo[11.11.2.12, 22.02, 12.04, 11]heptacosa-5, 16, 25-trien-13-ol. Canonical SMILES: C1CCN2CCC3C (=CC (CCC=CC1) (C4C3 (C2) CC5N4CCCCC=C5) O) C6=NC=CC7=C6NC8=CC=CC=C78. Density: 1.26±0.1 g/cm³. Catalog: ACM104196681.
Manzamine A
Manzamine A is an alkaloid in the class of β-carboline isolated from the marine sponges. It acts as an inhibitor of glycogen synthase kinase 3β (GSK3β). It exhibits inhibitory effects against growth of the rodent malaria parasite Plasmodium berghei in vivo. Synonyms: Keramamine A. Grades: ≥98%. CAS No. 104196-68-1. Molecular formula: C36H44N4O. Mole weight: 548.8.
Manzamine A
Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC 50 s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Keramamine A. CAS No. 104196-68-1. Pack Sizes: 1 mg. Product ID: HY-117025.
Manzamine A HCl
Other Alkaloids. Alternative Names: Manzamine A hydrochloride. CAS No. 104264-80-4. Mole weight: 585.2. Purity: 95%+. Catalog: ACM104264804.
Manzamine A hydrochloride
Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC 50 s of 10.2 μM and 1.5 μM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Keramamine A hydrochloride. CAS No. 104264-80-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117025A.
An inhibitor of monoamine oxidase B (MAO B) (IC50= 20 nM). Synonyms: (2S)-1-[4-[(3-chlorophenyl)methoxy]phenoxy]-3-methoxypropan-2-ol. CAS No. 124991-40-8. Molecular formula: C17H19ClO4. Mole weight: 322.78.
MAOS
MAOS is a modified Trinders reagent that can be used as a chromogenic probe for the determination of H 2 O 2. MAOS is strongly dependent on the pH of the reaction medium [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 82692-97-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-15923.
MAOS
MAOS is a modified Trinder's reagent used in hydrogen peroxide determination. Synonyms: 3-[(3,5-Dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt; Sodium 3-[(3,5-dimethylphenyl)ethylamino]-2-hydroxy-1-propanesulfonate; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethylaniline Sodium Salt. Grades: ≥95%. CAS No. 82692-97-5. Molecular formula: C13H20NNaO4S. Mole weight: 309.36.
mAP
Organic Light Emitting Diode (OLED). Alternative Names: 1,3-Bis(9,9-dimethylacridin-10(9H)-yl)benzene. CAS No. 1233947-20-0. Molecular formula: C36H32N2. Mole weight: 492.65 g/mol. Catalog: ACM1233947200.
MAP
Multiple Antigenic peptides (MAPs) are artificially branched peptides with lysine residues as the scaffold core, supporting the formation ≤8 branches with varying or the same peptide sequences. MAPs have been used to produce antibodies for immunological research. MAPs have a high molar ratio of peptide antigen to core molecule and does not require carrier protein to elicit antibody response. Synonyms: H-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-His-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Leu-Ala-Lys-Leu-Ala-Leu-Lys-Leu-Ala-Leu-Lys-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Leu-Ala-OH. Grades: >98%. Molecular formula: C180H331N47O37. Mole weight: 3745.92.
MAP4
MAP4 is a selective group III metabotropic glutamate receptor (mGluR) antagonist in some electrophysiological systems. It acts as a group II/group III agonist in certain neurochemical systems. It modulates transmission of gustatory inputs in the brain system. It has displayed its potency in the perforant path of rat hippocampal slices. Synonyms: (S)-2-Amino-2-methyl-4-phosphonobutyric acid; α-Methyl-AP4; MAP-4; MAP 4. Grades: ≥96% by HPLC. CAS No. 157381-42-5. Molecular formula: C5H12NO5P. Mole weight: 197.13.