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Mastoparan B (MPB) is a venom peptide isolated from Vespa basalis (black-bellied hornet), one of the dangerous vespine wasps found in Taiwan. Mastopran-B is the major active component of the venom of the hornet Vespa basalis and causes degranulation of mast cells as well as hemolysis on chicken, human and sheep erythrocytes. It also exhibits antimicrobial activity against both Gram-positive and -negative bacteria. Synonyms: MP-B; Mast cell degranulating peptide (vespa basalis). Grades: >96% by HPLC. CAS No. 137354-65-5. Molecular formula: C78H138N20O16. Mole weight: 1612.05.
Mastoparan-like peptide 12a
Mastoparan-like peptide 12a is a mast cell degranulating peptide with little hemolytic activity. It shows antimicrobial activity against the Gram-negative bacteria E.coli, the Gram-positive bacteria S.aureus and the fungus C.albicans.
Mastoparan-like peptide 12b
Mastoparan-like peptide 12b is a mast cell degranulating peptide with little hemolytic activity. It shows antimicrobial activity against the Gram-negative bacteria E.coli, the Gram-positive bacteria S.aureus and the fungus C.albicans.
Mastoparan-like peptide 12c precursor
Mastoparan-like peptide 12c precursor shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E.coli, the Gram-positive bacteria S.aureus and the fungus C.albicans).
Mastoparan-like peptide 12d
Mastoparan-like peptide 12d shows mast cell degranulation and antimicrobial activities against the Gram-negative bacteria E.coli, the Gram-positive bacteria S.aureus and the fungus C.albicans.
Mastoparan M
Mastoparan M exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes. It has a role as an antibacterial agent. Synonyms: L-Leucinamide, L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-; H-Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-NH2; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide; Mastoparan 12c (Vespa magnifica venom). Grades: ≥95%. CAS No. 79396-77-3. Molecular formula: C70H131N19O15. Mole weight: 1478.90.
Mastoparan M tetraacetate
Mastoparan M exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as hemolytic activity on chicken, human, and sheep erythrocytes. It has a role as an antibacterial agent. Synonyms: L-Leucinamide, L-isoleucyl-L-asparaginyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-, acetate (1:4); H-Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Ala-Lys-Lys-Leu-Leu-NH2.4CH3CO2H; L-isoleucyl-L-asparagyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide acetic acid. Grades: ≥95%. CAS No. 79396-78-4. Molecular formula: C70H131N19O15.4C2H4O2. Mole weight: 1719.12.
Mastoparan-T
Mastoparan-T is a chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to erythrocytes and no mast cell degranulation activity at physiological concentrations. Mastoparan-T is also a potent antimicrobial peptide against Gram-positive and Gram-negative bacteria.
Mastoparan-V1
Mastoparan-V1 is a chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to erythrocytes and no mast cell degranulation activity at physiological concentrations. Mastoparan-V1 is also a potent antimicrobial peptide against Gram-positive and Gram-negative bacteria. Synonyms: MP-V1. Grades: >96% by HPLC. Molecular formula: C81H140N22O19S. Mole weight: 1758.17.
Mastoparan-V2
Mastoparan-V2 is a chemotactic peptide for polymorphonucleated leukocytes (PMNL), but causing no hemolysis to erythrocytes and no mast cell degranulation activity at physiological concentrations. Mastoparan-V2 is also a potent antimicrobial peptide against Gram-positive and Gram-negative bacteria. Synonyms: MP-V2.
Mastoparan X
Mastoparan X is a GTP-binding regulatory protein ( G protein )-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 72093-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2705.
Mastoparan X
It is a G protein activator peptide that binds to Gi and Go. It also binds with high affinity to calmodulin (Kd~0.9 nM) and inhibits sarcoplasmic reticulum Ca2+-ATPase (Ki=4.4 mM). Synonyms: H-Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2; L-isoleucyl-L-asparagyl-L-tryptophyl-L-lysyl-glycyl-L-isoleucyl-L-alanyl-L-alanyl-L-methionyl-L-alanyl-L-lysyl-L-lysyl-L-leucyl-L-leucinamide; mastoparan-V; MP-V; Mas X. Grades: ≥95% by HPLC. CAS No. 72093-22-2. Molecular formula: C73H126N20O15S. Mole weight: 1555.97.
Mastoparan X
Mastoparan X. Group: Biochemicals. Grades: Purified. CAS No. 72093-22-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MASTP_PROSY Mastoparan
MASTP_PROSY Mastoparan has antibacterial activity. MASTP_PROSY Mastoparan was found in Protonectarina sylveirae [Brazilian wasp]. Grades: >96% by HPLC. Molecular formula: C75H128N20O17. Mole weight: 1581.94.
Masupirdine mesylate
Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist ( K i of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-502 mesylate. CAS No. 1791396-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109118A.
MAT2A-IN-9
MAT2A-IN-9 is a potent inhibitor of MAT2A (methionine adenosyltransferase 2A) and exhibits anti-tumor activity in MTAP-deleted PDX models. Synonyms: 4-amino-1-(2-chlorophenyl)-7-(trifluoro-methyl)pyrido[2,3-d]pyrimidin-2(1H)-one; GSK-4362676; IDE397. CAS No. 2439277-80-0. Molecular formula: C14H8ClF3N4O. Mole weight: 340.69.
MAT2A inhibitor 2
MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A ( MAT2A ) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13299-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112569.
MAT2A Inhibitor II, FIDAS-5
A cell-permeable fluorinated N,N-dialkylaminostilbene (FIDAS) analogue of FIDAS-3 that competes against SAM for MAT2A binding and is >2-fold more potent than FIDAS-3 in inhibiting MAT2A-catalyzed SAM synthesis both in cell-free assays (IC50 = 2.1uM) and in LS174T colorectal cancer (CRC) cultures (3uM). FIDAS-5 at 3uM is shown to completely inhibit the proliferation of LS174T for up to 7 d in vitro and effectively suppress HT29 CRC tumor expansion in mice in vivo (20mg/kg/day p.o.). Group: Biochemicals. Alternative Names: FIDAS5; Methionine S-Adenosyltransferase 2A Inhibitor II; (E)-4-(2-Chloro-6-fluorostyryl)-N-methylaniline. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C15H13CIFN, Molecular Weight: 261.73. US Biological Life Sciences.
Worldwide
Matairesinol
Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application [1]. Uses: Scientific research. Group: Natural products. CAS No. 580-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3312.
Matairesinol 4'-O- β-gentiobioside
Matairesinol 4'-O- β-gentiobioside. Group: Biochemicals. Grades: Plant Grade. CAS No. 106647-14-7. Pack Sizes: 5mg. Molecular Formula: C32H42O16, Molecular Weight: 682.67. US Biological Life Sciences.
Worldwide
Matairesinol 4'-O-β-gentiobioside
Matairesinol 4'-O-β-gentiobioside is a lignan found in the herbs of Trachelospermum jasminoides. Synonyms: (3R,4R)-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-[[3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyphenyl]methyl]oxolan-2-one. Grades: >98%. CAS No. 106647-14-7. Molecular formula: C32H42O16. Mole weight: 682.672.
Matairesionol
Matairesionol. Uses: For analytical and research use. Group: Impurity standards. CAS No. 580-72-3. Molecular Formula: C20H22O6. Mole Weight: 358.39. Catalog: APB580723.
Matcha Powder
Matcha Powder is made from finely milled or fine powder of fresh tender green tea leaf (Camellia sinensis (L.) O.Kuntze). Matcha originates from China Tang Dynasty (618-907), and then Spread to Japan and other countries. Nowadays matcha powder are very popular for its freshness, nutrition and the green conception. Group: Others. Matcha Powder; Camellia sinensis (L.) O.Kuntze. Cat No: EXTC-111.
Mathemycin A
It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C71H132N2O24. Mole weight: 1397.80.
Mathemycin B
It is produced by the strain of Act. sp. HIL Y-862O. It has an inhibitory effect on pathogenic fungi. It inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6). Molecular formula: C77H142N2O29. Mole weight: 1559.94.
mating pheromone Er-1
Pheromone Ingredients. Alternative Names: mating pheromone Er-1. CAS No. 118337-10-3. Catalog: ACM118337103.
mating pheromone Er-10
Pheromone Ingredients. Alternative Names: mating pheromone Er-10. CAS No. 120852-74-6. Catalog: ACM120852746.
Matlystatin A
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: N-Acetyl-S-(4-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-5-methyl-3-oxoheptyl)-L-cysteine; N-acetyl-S- (4- (2- (2- (2- (hydroxyamino) -2-oxoethyl) heptanoyl) hexahydropyridazine-3-carboxamido) -5-methyl-3-oxoheptyl) -L-cysteine. CAS No. 140626-94-4. Molecular formula: C27H47N5O8S. Mole weight: 601.76.
Matlystatin B
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.43 and 1.2, respectively. It has anti-gram-positive bacteria effect. Synonyms: 1(2H)-Pyridazinebutanamide, tetrahydro-N-hydroxy-6-[[[2-methyl-1-(1-oxopropyl)butyl]amino]carbonyl]-g-oxo-b-pentyl-, [6S-[1(S*),6R*(1R*,2R*)]]-; Matlystatin B1. CAS No. 140923-32-6. Molecular formula: C22H40N4O5. Mole weight: 440.58.
Matlystatin D
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively. Synonyms: Matlystatin D1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140638-25-1. Molecular formula: C27H44N6O6. Mole weight: 548.68.
Matlystatin E
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 19.3 and 59, respectively. Synonyms: Matlystatin E1; Pyrazolo(1,2-a)pyridazin-4-ium,8-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroxyamino)-2-oxoethyl)-1-oxohexyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(8-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyheptylidene)amino]oxidanide. CAS No. 140638-26-2. Molecular formula: C26H42N6O6. Mole weight: 534.65.
Matlystatin F
It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively. Synonyms: Matlystatin F1; Pyrazolo(1,2-a)pyridazin-4-ium,5-carboxy-1-(1-(((hexahydro-2-(2-(2-(hydroyamino)-2-oxoethyl)-1-oxoheptyl)-3-pyridazinyl)carbonyl)amino)-2-methylbutyl)-5,6,7,8-tetrahydro-,hydroxide,inner salt; [(3-{6-[{[1-(5-Carboxy-5,6,7,8-tetrahydropyrazolo[1,2-a]pyridazin-9-ium-1-yl)-2-methylbutyl]imino}(hydroxy)methyl]-1,2-diazinane-1-carbonyl}-1-hydroxyoctylidene)amino]oxidanide. CAS No. 140667-42-1. Molecular formula: C27H44N6O6. Mole weight: 548.68.
Matrigel
Heterocyclic Organic Compound. CAS No. 119978-18-6. Catalog: ACM119978186.
matrilysin
Found in rat uterus; at 19 kDa, the smallest member of peptidase family M10 (interstitial collagenase family). Similar in specificity to stromelysin, but more active on azocoll. Group: Enzymes. Synonyms: matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Enzyme Commission Number: EC 3.4.24.23. CAS No. 141256-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4304; matrilysin; EC 3.4.24.23; 141256-52-2; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Cat No: EXWM-4304.
Matrilysin (96-107)
Matrilysin (MAT) is a member of the matrix metalloproteinase (MMP) family which is believed to degrade components of the extracellular matrix (ECM) during processes of tissue remodeling. Synonyms: MMP7 (96-107).
Matrine
Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Matridin-15-one; Vegard; α-Matrine. CAS No. 519-02-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0164.
Matrine
Matrine is an alkaloid found in plants of the Sophora genus. The compound is an antioxidant with anti-tumoral properties and has neuroprotective effects in rodent models for Parkinson's disease. It inhibits inflammatory responses and was shown to attenuates collagen-induced arthritis in mice. Moreover, matrine can attenuate cardiac fibrosis and hepatitis B-induced liver damage. The compound can also agonise opioid receptors and has anti-nociceptive properties. Group: Other alkaloids. Alternative Names: Ex Sophporae Radix. CAS No. 519-02-8. Molecular formula: C15H24N2O. Mole weight: 248.36 g/mol. Appearance: White powder. Purity: 0.98. IUPACName: (1R, 2R, 9S, 17S)-7, 13-diazatetracyclo[7.7.1.02, 7.013, 17]heptadecan-6-one. Canonical SMILES: C1C[C@@H]2[C@H]3CCCN4[C@H]3[C@@H] (CCC4)CN2C (=O)C1. Density: 1.19 g/ml. Catalog: ACM519028-2.
Matrine
Matrine. Group: Biochemicals. Alternative Names: Sophoridine. Grades: Plant Grade. CAS No. 519-02-8. Pack Sizes: 20mg. Molecular Formula: C15H24N2O, Molecular Weight: 248.364. US Biological Life Sciences.
Worldwide
matriptase
This trypsin-like integral-membrane serine peptidase has been implicated in breast cancer invasion and metastasis. The enzyme can activate hepatocyte growth factor/scattering factor (HGF/SF) by cleavage of the two-chain form at an Arg residue to give active α- and β-HGF, but It does not activate plasminogen, which shares high homology with HGF.The enzyme can also activate urokinase plasminogen activator (uPA), which initiates the matrix-degrading peptidase cascade. Belongs in peptidase family S1A. Group: Enzymes. Synonyms: serine protease 14; membrane-type serine protease 1; MT-SP1; prostamin; serine protease TADG-15; tumor-associated differentially-expressed gene 15 protein; ST14; breast cancer 80 kDa protease; epithin; serine endopeptidase SNC19. Enzyme Commission Number: EC 3.4.21.109. CAS No. 241475-96-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4104; matriptase; EC 3.4.21.109; 241475-96-7; serine protease 14; membrane-type serine protease 1; MT-SP1; prostamin; serine protease TADG-15; tumor-associated differentially-expressed gene 15 protein; ST14; breast cancer 80 kDa protease; epithin; serine endopeptidase SNC19. Cat No: EXWM-4104.
Matriptase-2 from Human, Recombinant
Matriptase-2 (TMPRSS6) is a type II transmembrane serine protease mainly produced by the liver. It acts as a potent negative regulator of hepcidin, a hepatic peptide hormone and integral player in regulating iron homeostasis. Group: Enzymes. Synonyms: Transmembrane protease serine 6; TMPRSS6; Matriptase-2. Enzyme Commission Number: EC 3.4.21.-. Purity: Purified by multi-step chromatography. Matriptase-2. Mole weight: ~84 kDa; a-subunit: ~56kDa; b-subunit: ~28kDa. Activity: ~2.5U/ul. Stability: Stable for at least 6 months when stored at -20°C. Recommended Assay Buffer: 100mM TRIS, pH 9.0, containing 0.5mg/ml BSA. Do not store diluted solutions. Storage: Short Term Storage: -20°C; Long Term Storage: -80°C. Form: Liquid. In 100mM TRIS-HCl, pH 9.0, containing 150 mM sodium chloride and 20% glycerol. Source: Drosophila Schneider 2 (S2) cells. Species: Human. Transmembrane protease serine 6; TMPRSS6; Matriptase-2. Cat No: NATE-0857.
Matriptase-IN-2
Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268874-09-4. Pack Sizes: 5 mg. Product ID: HY-W783268A.
Matrix Metalloproteinase-13 (HisoTag) from Human, Recombinant
Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular pr..., a ca2+- and zn2+- binding catalytic domain, a hinge region, and a c-terminal hemopexin domain. hydrolyzes collagen type ii 5-6 times faster than collagens type i and iii. exhibits high activity towards gelatin and degrades α1-antichymotrypsin and plasminogen activator inhibitor-2. Group: Enzymes. Synonyms: Collagenase-3; Matrix metallopeptidase 13; MMP13; CLG3; MANDP1; MMP-13. Purity: >90% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 60 kDa. Activity: >50 mU/mg protein. Storage: < -70°C; Avoid freeze/thaw. Form: Liquid. Source: S. frugiperda. Species: Human. Collagenase-3; Matrix metallopeptidase 13; MMP13; CLG3; MANDP1; MMP-13. Cat No: NATE-0859.
Matrix Metalloproteinase-1 from Human, Recombinant
Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular processe...may also undergo autocatalysis to yield a 27 kda/22 kda active enzyme. expressed by a large number of cell types. cleaves fibrillar type i collagen. must be activated just prior to use. Group: Enzymes. Synonyms: Matrix Metalloproteinase 1; Human Interstitial Collagenase; Collagenase-1; EC 3.4.24.7; vertebrate collagenase. Enzyme Commission Number: EC 3.4.24.7. CAS No. 9001-12-1. Purity: >90% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 56 kDa/52 kDa. Activity: >15 mU/mg protein. Storage: < -70°C; Avoid freeze/thaw. Form: Liquid. Source: Human Rheumatoid Synovial Fibroblast. Species: Human. Matrix Metalloproteinase 1; Human Interstitial Collagenase; Collagenase
Matrix Metalloproteinase-2 from Human, Recombinant
Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular processe... does not interfere with activation. may contain up to 10% timp proteins. during storage, a small portion (less than 10%) of the enzyme may also become activated. Group: Enzymes. Synonyms: 72 kDa Gelatinase; Matrix Metalloproteinase 2; Gelatinase A; EC 3.4.24.24; type IV collagenase; 3/4 collagenase; matrix metalloproteinase 5; 72 kDa gelatinase type A; collagenase IV; collagenase type IV; MMP 2; type IV collagen metalloproteinase; type IV collagenase/gelatinase. Enzyme Commission Number: EC 3.4.24.24. CAS No. 146480-35-5. Purity: >90% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 72 kDa. Storage: < -70°C; Avoid freeze/thaw. Form: Liquid. Source: CHO Cells. Spe
Matrix Metalloproteinase-3 from Human, Recombinant
Matrix metalloproteinase-3 (MMP-3) also known as stromelysin-1 and transin (EC 3.4.24.17) cleaves a number of substrates including cartilage proteoglycan, collagen types II, III, IV, V and IX, fibronectin, laminin, and can activate MMP 1. MMP-3 is secreted as 57 and 59 kDa proenzymes and can be activated in vitro by organomercurials (e.g., 4 aminophenylmercuric acetate, APMA) and in vivo by proteases via intermediate forms to a 45 kDa active MMP 3 enzyme. Further autolysis to a 28 kDa form can also occur. MMP-3 is thought to play an important role in pathophysiological degradation processes associated with conditions such as rheumatoid arthritis and cancer cell invas...C 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Enzyme Commission Number: EC 3.4.24.17. CAS No. 79955-99-0. Purity: >95% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 57 kDa. Storage: < -70°C; Avoid freeze/thaw. Form: Lyophilized from 100 mM NaCl, 50 mM HEPES, pH 7.3. Species: Human. Stromelysin 1; EC 3.4.24.17; matrix metalloproteinase 3; proteoglycanase; collagenase activating protein; procollagenase activator; transin; MMP-3; neutral proteoglycanase; stromelysin; collagen-activating protein. Cat No: NATE-0861.
Matrix Metalloproteinase-7 from human, Recombinant
MMP-7 degrades general matrix components and may have a role in processes such as host defense, cell proliferation, and protein turnover as well as tissue remodeling. Group: Enzymes. Synonyms: MMP7; matrix metallopeptidase 7; MMP-7; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. CAS No. 141256-52-2. Matrix Metalloproteinase. Storage: -70°C. Form: buffered aqueous solution, Supplied in a buffer containing the active enzyme in 10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 5 mM calcium chloride. Source: E. coli. Species: Human. MMP7; matrix metallopeptidase 7; MMP-7; matrin; uterine metalloendopeptidase; matrix metalloproteinase 7; putative (or punctuated) metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative metalloproteinase; MMP. Cat No: NATE-0451.
Matrix Metalloproteinase-8 from Human, Recombinant
Full-length recombinant human neutrophil pro-collagenase (MMP-8), latent form. Matrix metalloproteinase 8 (MMP-8), or neutrophil collagenase, degrades interstitial collagens, acting preferentially on collagen type I. Increased full-length MMP-8 protein was associated with infiltration into the skin of neutrophils, which are the major cell type that expresses MMP-8. MMP-8 is synthesized and stored in specific granules in neutrophil leukocytes. MMP-8 activity is therefore regulated by factors such as surface-bound ligands (IgG or complement components) that release it through degranulation.Once released and activated through proteolytic or oxidative mechanisms, MMP-8 p...ollagenase activity. Group: Enzymes. Synonyms: Neutrophil collagenase; EC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL; HNC; CLG1. Enzyme Commission Number: EC 3.4.24.34. CAS No. 9001-12-1. Purity: Greater than 90% as determined by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 75 kDa. Activity: 100 units/ml. Stability: MMP-8 although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. Neutrophil collagenase; EC 3.4.24.34; Matrix metalloproteinase-8; MMP-8; PMNL collagenase; PMNL-CL; HNC; CLG1. Cat No: NATE-0862.
Matrix Metalloproteinase-9 from Human, Recombinant
Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular processe...(less than 10%) of the enzyme may also become activated. requires activation prior to use. a simple activation protocol is included. Applications: Immunoblotting (1 ug protein/lane) substrate cleavage assay (1 ug protein/lane) zymography (1 ug protein/lane). Group: Enzymes. Synonyms: Gelatinase B; EC 3.4.24.35; 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV; collagenase type IV; gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase. Enzyme Commission Number: EC 3.4.24.35. CAS No. 146480-36-6. Purity: >90% by SDS-PAGE. Matrix Metalloprotei
Matrix protein 1 (229-237)
Matrix protein 1 (229-237) is a peptide derived from M1, a matrix protein of the influenza virus. And it is associated with Human respiratory syncytial virus and lung carcinoma. Synonyms: M1 (229-237).
Matrix protein 1 (27-35)
Matrix protein 1 (27-35) is a peptide derived from M1, a matrix protein of the influenza virus. And it is associated with Influenza A virus and lung carcinoma. Synonyms: M1 (27-35).
Matrix Protein M1 (58-66) (Influenza A virus)
It is the epitope of influenza A virus matrix protein. Synonyms: Matrix protein 1 (58-66); FLUM1 A2 peptide (58-66); CEF1, Influenza Matrix Protein M1 58-66; Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu; glycyl-L-isoleucyl-L-leucyl-glycyl-L-phenylalanyl-L-valyl-L-phenylalanyl-L-threonyl-L-leucine. Grades: ≥95%. CAS No. 141368-69-6. Molecular formula: C49H75N9O11. Mole weight: 966.17.
Matrixyl 3000
Matrixyl 3000 is an anti-aging ingredient developed by Sederma. Matrixyl 3000 is a combination of palmitoyl oligopeptide and palmitoyl tetrapeptide-7. Grades: 98%.
Matrixyl / Palmitoyl Pentapeptide-3/4 (Pal-KTTKS)
Matrixyl / Palmitoyl Pentapeptide-3/4 (Pal-KTTKS). CAS No. 214047-00-4. Product ID: CDC10-0665. Category: Cosmetic Active Peptide. Product Keywords: Cosmetic Ingredients; Active Ingredients; Cosmetic Active Peptide; ; CDC10-0665; Matrixyl / Palmitoyl Pentapeptide-3/4 (Pal-KTTKS); Cosmetic Active Peptide; ; 214047-00-4. Purity: 98%/99%. Applications: For collagen synthesis, repair the damaged skin and anti-aging.
Matuzumab is a humanized monoclonal antibody that binds to the epidermal growth factor receptor (EGFR). EGFR existing on the surface of normal and tumor cells binds to EGF (epidermal growth factor) and other EGF family growth factors, which leads to the activation of EGFR. Matuzumab is used as an anti-cancer drug. Uses: Anti-cancer drug. Synonyms: Matuzumab; Emd 72000; Emd-72000; Kgaa; Merck kgaa. Grades: 95%. CAS No. 339186-68-4.
Matuzumab
Matuzumab (EMD 72000) is a humanized anti- EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMD 72000. CAS No. 339186-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9969.
Mauritianin
Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Group: Inhibitors. CAS No. 109008-28-8. Molecular formula: C33H40O19. Mole weight: 740.66. Appearance: Solid. Purity: 0.9953. Canonical SMILES: O=C1C (O[C@H]2[C@@H] ([C@H] ([C@@H] (O)[C@@H] (CO[C@H]3[C@@H] ([C@@H] ([C@@H] (O)[C@H] (C)O3)O)O)O2)O)O[C@@]4 ([H])[C@@H] ([C@@H] ([C@@H] (O)[C@H] (C)O4)O)O)=C (C5=CC=C (O)C=C5)OC6=CC (O)=CC (O)=C61. Catalog: ACM109008288.
Mauritianin
Mauritianin. Group: Biochemicals. CAS No. 109008-28-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Maurocalcine
Maurocalcine is a highly potent cell-penetrating peptide isolated from the Tunisian scorpion Maurus palmatus. It is an activator of Ca2+ release channel and a Ryanodine receptors agonist. It is a 33-mer basic peptide cross-linked by three disulfide bridges. Synonyms: MCa. Grades: >97%.
Mavacamten
Mavacamten (MYK461) is an orally active modulator of cardiac myosin , with IC 50 s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MYK461; SAR439152. CAS No. 1642288-47-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109037.
Mavacamten impurity 1
Mavacamten impurity 1. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H14O7. Mole Weight: 270.24. Catalog: APB12386.
Mavacamten impurity 10
Mavacamten impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C9H14N2O3. Mole Weight: 198.22. Catalog: APB12382.
Mavacamten impurity 11
Mavacamten impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5759-79-5. Molecular Formula: C12H13N3O2. Mole Weight: 231.26. Catalog: APB5759795.
Mavacamten impurity 12
Mavacamten impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2704235-12-9. Molecular Formula: C15H19N3O2. Mole Weight: 273.34. Catalog: APB2704235129.
Mavacamten impurity 13
Mavacamten impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-64-9. Molecular Formula: C15H19N3O2. Mole Weight: 273.34. Catalog: APB1642288649.
Mavacamten impurity 14
Mavacamten impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-37-9. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289379.
Mavacamten impurity 15
Mavacamten impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-31-3. Molecular Formula: C17H23N3O2. Mole Weight: 301.39. Catalog: APB1642289313.