A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Mca-PL is a fluorogenic peptide that can be used in the synthesis of Mca-PLGL-Dpa-AR-NH2, a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-7 Fluorogenic Substrate Control; Mca-Pro-Leu-OH; MMP-2/MMP-7 Fluorogenic Substrate Control; N-[1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl]-L-leucine. Grade: ≥95%. CAS No. 140430-55-3. Molecular formula: C23H28N2O7. Mole weight: 444.48.
Mca-PLAQAV-Dpa-RSSSR-NH2
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent substrate peptide that can be used to detect ADAM9, ADAM10, and tumor necrosis factor-α converting enzyme (TACE/ADAM17). Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescence resonance energy transfer-based substrate, and its activity can be determined by changes in fluorescence intensity upon cleavage (Ex = 320 nm; Em = 405 nm)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 192723-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3722.
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85·105 M-1s-1. It is a poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53·105 M-1s-1) and MMP-9 (kcat/Km = 0.33·105 M-1s-1). Synonyms: L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-; 1-[(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-L-alaninamide. Grade: 95%. CAS No. 891198-38-2. Molecular formula: C53H70N12O20. Mole weight: 1195.19.
Mca-Pro-Leu-OH
Mca-Pro-Leu is a fluorescently labeled dipeptide[1]. Uses: Scientific research. Category: Peptides. Alternative Names: Mca-Pro-Leu. CAS No. 140430-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4645.
m-Carborane
m-Carborane. Alternative Names: 1,7-DICARBADODECARBORANE(12);M-CARBORANE;1,7-Dicarba-closo-dodecaboran;1,7-Dicarba-closo-dodecaborane(12);1,7-Dicarbadodecaboran;1,7-Dicarbadodecaboran(12);1,7-Dicarbadodecaborane;1,7-dicarbadodecaborane(12). CAS No. 16986-24-6. Molecular formula: C2H2B10. Mole weight: 134.2g/mol. Purity: N/A. SMILES: [B]1[B][B][B][B]C2[B]C([B]2)[B][B][B]1. InChI: InChI=1S/C2H2B10/c3-1-4-2(3)6-8-10-12-11-9-7-5-1/h1-2H.
m-Carborane
m-Carborane. Group: Biochemicals. Alternative Names: 1, 7-Dicarbadodecaborane (12). Grades: Highly Purified. CAS No. 16986-24-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C2H12B10. US Biological Life Sciences.
Worldwide
m-Carborane-1-carboxylic Acid
m-Carborane-1-carboxylic Acid is used as a reactant or reagent in the synthetic preparation of ortho-carbaborane indomethacin pharmacophores as selective COX-2 enzyme inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 18581-81-2. Pack Sizes: 15mg, 30mg. Molecular Formula: C3H12B10O2, Molecular Weight: 188.24. US Biological Life Sciences.
Worldwide
m-Carboxybenzaldehyde
White powder, keep cold, 98%. Synonym: 3-Formylbenzoic Acid. CAS No. 619-21-6. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 150.13. MP/BP: M.P. 173-175. Order No: FR-2055.
Frinton Laboratories
Mca-SEVNLDAEFK(Dnp)-NH2
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802078-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4920.
MCA-SEVNLDAEFR-K(Dnp)-RR, amide
It is a FRET-based substrate. Synonyms: Mca-(Asn670, Leu671)-APP770(667-676)-Lys(Dnp)-Arg-Arg amide; MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-(Asn670, Leu671)-Amyloid beta/A4 Protein Precursor770(667-676)-Lys(Dnp)-Arg-Arg amide. Grade: ≥95%. CAS No. 438625-61-7. Molecular formula: C86H125N27O29. Mole weight: 2001.08.
Mca-YVADAP-Lys(Dnp)-OH
Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). It is cleaved by caspase-1 or ACE2 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify enzyme activity. Synonyms: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH; Caspase-1 Fluorogenic Substrate V; N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-. Grade: ≥95%. CAS No. 189696-01-3. Molecular formula: C53H64N10O19. Mole weight: 1145.15.
MCB-36
MCB-36 is a VHL-recruiting pan-KRAS PROTAC degrader without affecting KRAS transcription. MCB-36 exhibits minimal effects on HRAS and NRAS protein levels. MCB-36 binds to the GDP-loaded state of G12D, G12C, G12V, and wild-type KRAS with high affinities Kd ? 1 pM). MCB-36 decreases p-ERK levels, leading to cell apoptosis. MCB-36 effectively suppress KRASG12C inhibitor-resistant cancer cells and remodel the tumor immune microenvironment. MCB-36 can be used for the study of colorectal cancer and lung cancer (Pink: Target protein ligand; Blue: E3 ligand (HY-112078); Black: Linker (HY-W091879))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104382-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176786.
MCB-613
MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator (SMS), super-stimulates SRCs transcriptional activity.MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS).MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1162656-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19625.
MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885
MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Compound Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722697-86-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-160497.
MC-betaglucuronide-MMAE-1
MC-betaglucuronide-MMAE-1 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide. Uses: Scientific research. Category: Signaling pathways. CAS No. 1703778-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136317.
m-CBP
Phosphorescent host material and TADF emitter in OLEDs. Alternative Names: 3,3'-Di(9H-carbazol-9-yl)-1,1'-biphenyl. CAS No. 342638-54-4. Molecular formula: C36H24N2. Mole weight: 484.59. IUPAC Name: 9-[3-(3-carbazol-9-ylphenyl)phenyl]carbazole. SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC=CC(=C4)C5=CC(=CC=C5)N6C7=CC=CC=C7C8=CC=CC=C86. InChI: InChI=1S/C36H24N2/c1-5-19-33-29(15-1)30-16-2-6-20-34(30)37(33)27-13-9-11-25(23-27)26-12-10-14-28(24-26)38-35-21-7-3-17-31(35)32-18-4-8-22-36(32)38/h1-24H.
MCC950
MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12815.
MCC950
MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. Group: Inhibitors. Alternative Names: CP-456773, CRID3. CAS No. 210826-40-7. Pack Sizes: 5mg. Product ID: S8930. Formula: C20H24N2O5S. Smiles: CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O. Storage Conditions: 3 years -20°C powder.
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12815A.
MCC950 Sodium
MCC950 Sodium is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes. Group: Inhibitors. Alternative Names: CP-456773 Sodium, CRID3 Sodium. CAS No. 256373-96-3. Pack Sizes: 10mg. Product ID: S7809. Formula: C20H23N2O5S.Na. Smiles: CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+]. Storage Conditions: 2 years -80 in solvent.
United States; Europe
MCC-AAQ-Exa
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3052836-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174279.
MCdef
MCdef is a defensin-like peptide detected in hemocytes of Manila clams (Ruditapes philippinarum). MCdef showed highest activity against Streptococcus iniae and Staphylococcus aureus.
Mc-Dexamethasone
Mc-Dexamethasone is a drug-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasoneconjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. Category: Active pharmaceutical ingredients. CAS No. 1618096-56-2. Product ID: API1618096562. Molecular formula: C29H38FN3O6. Mole weight: 543.636.
MC-DM1
MC-DM1 is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody agent conjugate (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375089-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136286.
MCD Peptide
22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with potent convulsant activity. Synonyms: Peptide 401; Mast Cell Degranulating (MCD) Peptide; Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bridge: Cys3-Cys15, Cys5-Cys19); L-isoleucyl-L-lysyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinyl-glycyl-L-lysyl-L-asparaginamide (3->15),(5->19)-bis(disulfide). Grade: ≥95%. CAS No. 32908-73-9. Molecular formula: C110H192N40O24S4. Mole weight: 2587.22.
Mc-d-Val-d-Cit-PAB-PNP
Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1350456-68-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173161.
MC-EVCit-PAB-MMAE
MC-EVCit-PAB-MMAE (Linker-Payload 11) is a drug-linker conjugates for ADC. MC-EVCit-PAB-MMAE contains the ADCs linker (MC-EVCit-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873452-49-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-154915.
MCF-7 Transfection Reagent
Transfection Reagent for MCF7 Breast Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1766.
Nevada, Texas, USA
MC-GGFG-AM-(10Me-11F-Camptothecin)
MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873460-70-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153360.
MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1
MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360). Modifying groups can be added group. MC-GGFG-AM-(10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(2-Amino-4-fluoro-5-methylphenyl)-2-chloroethanone. CAS No. 1241391-14-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-400770.
MC-GGFG-Exatecan
MC-GGFG-Exatecan (MC-GGFG-DX8951) is a agent-linker conjugate for ADC. MC-GGFG-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-Exatecan shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-GGFG-DX8951. CAS No. 1600418-29-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114233.
MC-GGFG-PAB-Exatecan
MC-GGFG-PAB-Exatecan (Compound 94) is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2928560-25-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160967.
MC-Gly-Gly-Phe
MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC). Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-15-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-44235.
MC-Gly-Gly-Phe-Gly
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mc-GGFG-OH. CAS No. 2413428-36-9. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-44246.
MC-Gly-Gly-Phe-Gly
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs). Synonyms: (S)-5-Benzyl-18-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecan-1-oic acid. Grade: >98.0%. CAS No. 2413428-36-9. Molecular formula: C25H31N5O8. Mole weight: 529.54.
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-. Grade: >98.0%. CAS No. 1599440-25-1. Molecular formula: C28H36N6O10. Mole weight: 616.62.
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-25-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-131990.
MC-Gly-Gly-Phe-Gly-PAB-MMAE
MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055607-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132134.
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-A1811 Drug-linker. CAS No. 2414254-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148668.
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414254-52-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148668A.
MCH (human, mouse, rat)
MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Synonyms: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grade: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84.
m-Chloro Hippuric Acid
m-Chloro Hippuric Acid. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid; N-(3-Chlorobenzoyl)glycine; NSC 201882; m-Chlorohippuric Acid; N-(3-Chlorobenzoyl)glycine. Grades: Highly Purified. CAS No. 57728-59-3. Pack Sizes: 1g. Molecular Formula: C9H8ClNO3, Molecular Weight: 218.62. US Biological Life Sciences.
m-Chlorophenylbiguanide hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2113-5-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
MCI-INI-3
MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3 (with a Ki value of 0.55 μM for ALDH1A3 and a Ki value of 78.2 μM for ALDH1A1). MCIINI-3 inhibits the biosynthesis of retinoic acid and reduces the viability of GSC-83 and GSC-326 glioblastoma cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1011366-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-169884.
MCL 0020
MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Synonyms: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grade: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73.
MCL 0020
MCL 0020. Group: Biochemicals. Grades: Purified. CAS No. 475498-26-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MCL-1/BCL-2-IN-1
MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 4.45 and 3.18 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493256-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129681.
Mcl-1 inhibitor 6
Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a Kd of 0.23 nM and a Ki of 0.02 μM. Mcl-1 inhibitor 6 possesses superior selectivity over other Bcl-2 family members (Bcl-2, Bcl2A1, Bcl-xL, and Bcl-w, Kd>10 μM). Mcl-1 inhibitor 6 is a potent antitumor agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2598978-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132307.
MCM-22
MCM-22. CAS No. 12173-28-3.
MCM-41
MCM-41. CAS No. 12173-28-3.
MCM-41
MCM-41.
Mc-MMAD
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. Uses: Adcs cytotoxin-linker. Synonyms: Mc MMAD; McMMAD. Grade: >98%. CAS No. 1401963-15-2. Molecular formula: C51H77N7O9S. Mole weight: 964.26.
Mc-MMAE
Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-monomethylauristatin E. CAS No. 863971-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15741.
Mc-MMAE
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Synonyms: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grade: ≥98%. CAS No. 863971-24-8. Molecular formula: C49H78N6O10. Mole weight: 911.18.
McMMAF
McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl monomethylauristatin F. CAS No. 863971-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15578.
Mc-MMAF
Mc-MMAF is a protective group-conjugated MMAF, MMAF is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin and it has lower cytotoxic activity than MMAE. Uses: Sgd 1269 is a potent tubulin inhibitor and is a toxin payload in antibody drug conjugate. it is a useful agent for make antibody drug conjugate (adc) for targeted drug delivery. Synonyms: SGD-1269; SGD 1269; SGD1269; mc-MMAF; mcMMAF; L4-MMAF; Maleimidocaproyl-MMAF; Maleimidocaproyl monomethylauristatin F; Mafodotin.((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grade: ≥98%. CAS No. 863971-19-1. Molecular formula: C49H76N6O11. Mole weight: 925.18.
McN3716
McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl palmoxirate; NSC359682. CAS No. 69207-52-9. Pack Sizes: 1 mg. Product ID: HY-U00159.
McN-A 343
McN-A 343. Group: Biochemicals. Grades: Purified. CAS No. 55-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MCOPPB trihydrochloride
MCOPPB trihydrochloride is a nociceptin receptor agonist with pKi of 10. Uses: Scientific research. Category: Signaling pathways. CAS No. 1108147-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13101.
MCOPPB Trihydrochloride
A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. Group: Biochemicals. Alternative Names: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059. Grades: Highly Purified. CAS No. 1108147-88-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Mcpa-1-Butyl Ester
Mcpa-1-Butyl Ester. Alternative Names: ((4-chloro-o-tolyl)oxy)-aceticacibutylester;(4-chloro-2-methylphenoxy)-aceticacibutylester;2-methyl-4-chlorophenoxyaceticacidn-butylester;butyl2-methyl-4-chlorophenoxyacetate;butyl4-chloro-o-tolyloxyacetate;mcpa,butylester;mcpabutyl;mcpbutylester. CAS No. 1713-12-8. Product ID: ACM1713128. Molecular formula: C13H17ClO3. Mole weight: 256.72528. Alfa Chemistry - ISO 9001:32057 Certified.
MCPA-d3
MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352431-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0859S1.
MCPA-[d3]
MCPA-[d3]. Synonyms: MCPA D3; (4-Chloro-2-methylphenoxy-2,?3,?5-d3)?acetic Acid. Grade: 98% atom D. CAS No. 352431-14-2. Molecular formula: C9H6D3ClO3. Mole weight: 203.64.
m-CPBG hydrochloride
m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(3-Chlorophenyl)biguanide hydrochloride. CAS No. 2113-5-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-100938.
MCP(Modified Citrus Pectin)
MCP(Modified Citrus Pectin). Categories: ore.
CA, FL & NJ
Mc-Pro-PAB-MMAE
Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766450-03-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171060.
m-Cresol
500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-500g. Molecular Weight 108.14. See USA prepack pricing.
m-Cresol
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-100g. Molecular Weight 108.14. See USA prepack pricing.