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Mavacamten impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-02-8. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289028.
Mavacamten impurity 17
Mavacamten impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-68-3. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB1642288683.
Mavacamten impurity 18
Mavacamten impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-16-4. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB1642289164.
Mavacamten impurity 19
Mavacamten impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-97-8. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB1642288978.
Mavacamten impurity 2
Mavacamten impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C9H15N3O3. Mole Weight: 213.24. Catalog: APB12383.
Mavacamten impurity 20
Mavacamten impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-54-0. Molecular Formula: C15H19N3O4. Mole Weight: 305.33. Catalog: APB1642289540.
Mavacamten impurity 21
Mavacamten impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-43-7. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB1642289437.
Mavacamten impurity 22
Mavacamten impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-38-0. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289380.
Mavacamten impurity 23
Mavacamten impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-11-9. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289119.
Mavacamten impurity 24
Mavacamten impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-74-4. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289744.
Mavacamten impurity 25
Mavacamten impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-56-2. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB1642289562.
Mavacamten impurity 26
Mavacamten impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-29-9. Molecular Formula: C17H23N3O2. Mole Weight: 301.39. Catalog: APB1642289299.
Mavacamten impurity 27
Mavacamten impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-26-6. Molecular Formula: C17H23N3O2. Mole Weight: 301.39. Catalog: APB1642289266.
Mavacamten impurity 28
Mavacamten impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-62-0. Molecular Formula: C16H21N3O3. Mole Weight: 303.36. Catalog: APB1642289620.
Mavacamten impurity 29
Mavacamten impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-04-0. Molecular Formula: C16H18N4O2. Mole Weight: 298.35. Catalog: APB1642289040.
Mavacamten impurity 3
Mavacamten impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 66400-12-2. Molecular Formula: C10H16N2O3. Mole Weight: 212.25. Catalog: APB66400122.
Mavacamten impurity 30
Mavacamten impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-69-4. Molecular Formula: C16H21N3O2. Mole Weight: 287.36. Catalog: APB1642288694.
Mavacamten impurity 31
Mavacamten impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-74-1. Molecular Formula: C15H18FN3O2. Mole Weight: 291.33. Catalog: APB1642288741.
Mavacamten impurity 32
Mavacamten impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-66-1. Molecular Formula: C16H21N3O3. Mole Weight: 303.36. Catalog: APB1642288661.
Mavacamten impurity 33
Mavacamten impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-65-0. Molecular Formula: C16H21N3O3. Mole Weight: 303.36. Catalog: APB1642288650.
Mavacamten impurity 34
Mavacamten impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-60-5. Molecular Formula: C17H23N3O3. Mole Weight: 317.39. Catalog: APB1642288605.
Mavacamten impurity 35
Mavacamten impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-94-8. Molecular Formula: C15H18BrN3O2. Mole Weight: 352.23. Catalog: APB1642289948.
Mavacamten impurity 36
Mavacamten impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642289-61-9. Molecular Formula: C15H18ClN3O2. Mole Weight: 307.78. Catalog: APB1642289619.
Mavacamten impurity 37
Mavacamten impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-79-6. Molecular Formula: C15H18BrN3O2. Mole Weight: 352.23. Catalog: APB1642288796.
Mavacamten impurity 38
Mavacamten impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1642288-72-9. Molecular Formula: C15H18ClN3O2. Mole Weight: 307.78. Catalog: APB1642288729.
Mavacamten impurity 4
Mavacamten impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67463-81-4. Molecular Formula: C12H21N3O3. Mole Weight: 255.32. Catalog: APB67463814.
Mavacamten impurity 5
Mavacamten impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H17ClN4O4. Mole Weight: 340.76. Catalog: APB12377.
Mavacamten impurity 6
Mavacamten impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H18N4O5. Mole Weight: 322.32. Catalog: APB12378.
Mavacamten impurity 7
Mavacamten impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C10H16N2O3. Mole Weight: 212.25. Catalog: APB12379.
Mavacamten impurity 8
Mavacamten impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H19N3O3. Mole Weight: 289.34. Catalog: APB12381.
Mavacamten impurity 9
Mavacamten impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C22H27N5O4. Mole Weight: 425.49. Catalog: APB12380.
Mavacoxib
Mavacoxib. Group: Biochemicals. Alternative Names: 4-[5-(4-Fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-Fluorophenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide; Mavacoxib; PHA 739521; Trocoxil. Grades: Highly Purified. CAS No. 170569-88-7. Pack Sizes: 100mg. Molecular Formula: C16H11F4N3O2S, Molecular Weight: 385.34. US Biological Life Sciences.
Worldwide
Mavacoxib
Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170569-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119447.
Mavacoxib
Mavacoxib, a pyrazol derivative, has been found to be a COX-2 Inhibitor that could be used in pain and inflammation therapy for dogs. Synonyms: Mavacoxib; PHA-739521; PHA739521; PHA 739521; PHA 739,521; PHA739,521; PHA-739,521; Mavacoxib. trade name Trocoxil; UNII-YFT7X7SR77; 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide. Grades: 98%. CAS No. 170569-88-7. Molecular formula: C16H11F4N3O2S. Mole weight: 385.34.
Mavacoxib-d4
Mavacoxib-d4. Group: Biochemicals. Alternative Names: 4-[5-(4-Fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide-d4; 4-[5-(4-Fluorophenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide-d4; Mavacoxib-d4; PHA 739521-d4; Trocoxil-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C16H7D4F4N3O2S, Molecular Weight: 389.36. US Biological Life Sciences.
Worldwide
Mavatrep
Mavatrep is an orally bioavailable, potent and selective TRPV1 antagonist with Ki value of 6.5 nM, which exhibits minimal effect on the enzymatic activity of CYP isoforms 3A4, 1A2, and 2D6. It antagonizes capsaicin-induced Ca2+ influx, with an IC50 value of 4.6 nM in a TRPV1 functional assay, using cells expressing recombinant human TRPV1 channels. It blocks the activation of hTRPV1 channels by Capsaicin and pH in a concentration-dependent fashion, with IC50 values of 23 and 6.8 nM respectively. It exhibits superior pharmacodynamic properties in the CFA model of inflammatory pain in vivo. It was selected for clinical development for the treatment of pain. It was developed by Johnson & Johnson and now in clinic phase 1 with no progress. Uses: Mavatrep was selected for clinical development for the treatment of pain. Synonyms: JNJ-39439335; JNJ 39439335; JNJ39439335; 2-[2-[2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-3H-benzimidazol-5-yl]phenyl]propan-2-ol. Grades: >98 %. CAS No. 956274-94-5. Molecular formula: C25H21F3N2O. Mole weight: 422.44.
Mavoglurant
Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist (IC50=30 nM), as a selective non-competitive antagonist. Synonyms: AFQ056; AFQ-056; AFQ 056; (3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester; methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-3,3a,5,6,7,7a-hexahydro-2H-indole-1-carboxylate. Grades: ≥95%. CAS No. 543906-09-8. Molecular formula: C19H23NO3. Mole weight: 313.39.
Mavoglurant
Mavoglurant (AFQ056) is a potent, selective, non-competitive and orally active mGluR5 antagonist, with an IC 50 of 30 nM. Mavoglurant shows a >300 fold selectivity for the mGluR5 over all targets (238) tested. Mavoglurant can be used for the research of Fragile X syndrome (FXS), and L-dopa induced dyskinesias in Parkinson's disease [1] [1] [2]. Mavoglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ056. CAS No. 543906-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15257.
Mavoglurant racemate
Mavoglurant racemate (AFQ-056 racemate) is the racemate of Mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist [1]. Mavoglurant (racemate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ-056 racemate. CAS No. 1636881-61-2. Pack Sizes: 2 mg; 5 mg. Product ID: HY-15257A.
Mavorixafor free base
Mavorixafor, also known as AMD11070, AMD070, X4P-001, is an orally bioavailable and potent CXCR4 inhibitor. AMD11070 is an antagonist of SDF-1α ligand binding (IC50 = 12.5 ± 1.3 nM), inhibits SDF-1 mediated calcium flux (IC50 = 9.0 ± 2.0 nM) and SDF-1α mediated activation of the CXCR4 receptor as measured by a Eu-GTP binding assay (IC50 =39.8 ± 2.5 nM) or a [(35)S]-GTPγS binding assay (IC50 =19.0 ± 4.1 nM), and inhibits SDF-1α stimulated chemotaxis (IC50 =19.0 ± 4.0 nM). AMD11070 abrogates melanoma cell migration and is significantly more effective than AMD3100. AMD11070 represents a novel therapeutic strategy for both B-RAF wild-type and mutated melanomas. Group: Antagonists. Alternative Names: AMD11070, AMD 11070, AMD-11070, AMD070, AMD 070, AMD-070, X4P-001, X49001, X4P 001, Mavorixafor. CAS No. 558447-26-0. Molecular formula: C21H27N5. Mole weight: 349.48. Appearance: Solid powder. Purity: >95%. IUPACName: (S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine. Canonical SMILES: NCCCCN ([C@@H]1C2=NC=CC=C2CCC1)CC3=NC4=C (N3)C=CC=C4. Catalog: ACM558447260.
Mavorixafor hydrochloride
Mavorixafor (AMD-070) hydrochloride is a potent, selective and orally available CXCR4 antagonist, with an IC 50 value of 13 nM against CXCR4 125 I-SDF binding. Mavorixafor hydrochloride also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC 50 of 1 nM and 9 nM, respectively. Mavorixafor hydrochloride can be used for the study of WHIM syndrome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD-070 hydrochloride; AMD-11070 hydrochloride. CAS No. 880549-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50101C.
Mavrilimumab
Mavrilimumab is a humanized monoclonal antibody targeting granulocyte macrophage colony-stimulating factor receptor (GM-CSF-R). Mavrilimumab has been investigated for the treatment of rheumatoid arthritis. Synonyms: CAM 3001; CAM-3001; CAM3001. CAS No. 1085337-57-0.
Mavrilimumab
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor ( GM-CSF ) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CAM 3001. CAS No. 1085337-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99031.
MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070931-57-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145723.
Maxacalcitol
Maxacalcitol is non-calcemic vitamin D3 analog and ligand of VDR-like receptors. Uses: Dermatologic agents. Synonyms: 22-Oxacalcitriol. Grades: >98%. CAS No. 103909-75-7. Molecular formula: C26H42O4. Mole weight: 418.61.
Maxacalcitol
Maxacalcitol (22-Oxacalcitriol), a vitamin D3 (HY-15398) analog, is an orally active VDR agonist. Maxacalcitol has a limited calcemic effect. Maxacalcitol has the potential for psoriasis and hyperparathyroidism research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 22-Oxacalcitriol. CAS No. 103909-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32339.
Synonyms: MC 1292. Grades: > 95%. CAS No. 132071-85-3. Molecular formula: C26H42O4. Mole weight: 418.6.
Maxacalcitol Intermediate
An intermediate of maxacalcitol, which is a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Molecular formula: C38H68O5Si2. Mole weight: 661.127.
Maxadilan, a potent vasodilator isolated from the salivary glands of the sand fly Lutzomyia longipalpis, specifically and effectively activates the mammalian PAC1 receptor, one of the three receptors of PACAP. Synonyms: H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Leu-Gln-Thr-Ser-Val-Gln-Thr-Thr-Ala-Thr-Phe-Thr-Ser-Met-Asp-Thr-Ser-Gln-Leu-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys51); Maxadilan (Lutzomyialongipalpis); L-cysteinyl-L-alpha-aspartyl-L-alanyl-L-threonyl-L-cysteinyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-alanyl-L-isoleucyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-glutaminyl-L-lysyl-L-glutaminyl-L-alanyl-L-histidyl-L-histidyl-L-seryl-L-asparagyl-L-valyl-L-leucyl-L-glutaminyl-L-threonyl-L-seryl-L-valyl-L-glutaminyl-L-threonyl-L-threonyl-L-alanyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-methionyl-L-alpha-aspartyl-L-threonyl-L-seryl-L-glutaminyl-L-leucyl-L-prolyl-glycyl-L-asparagyl-L-seryl-L-valyl-L-phenylalanyl-L-lysyl-L-alpha-glutamyl-L-cysteinyl-L-methionyl-L-lysyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-alaninamide (1->5),(14->51)-bis(disulfide). Grades: 95%. CAS No. 135374-80-0. Molecular formula: C291H466N86O94S6. Mole weight: 6865.82.
Maximin 1
Maximin 1 has antibacterial, antifungal, antiviral activity. The source of Maximin 1 is Chinese red belly toad, Bombina maxima, Yunnan, China, Asia. It is active against E. coli ATCC25922, S. aureus ATCC2592, B. pyocyaneus CMCCB10104, B. megatherium, B. dysenterium, K. pneumoniae, and C. albicans ATCC2002 (MIC 3-20 μM). It also has spermicidal effect. Grades: >95% by HPLC. Molecular formula: C120H209N33O35. Mole weight: 2674.14.
Maximin-11
Maximin-11 is from Bombina maxima and it shows antimicrobial activity against bacteria and against the fungus C.albicans. It has little hemolytic activity. Synonyms: Maximin-11 antimicrobial peptide.
Maximin 15
Maximin 15 has antibacterial and antifungal activities. The source of Maximin 15 is Bombina maxima [Giant fire-bellied toad].
Maximin 2
Maximin 2 has antibacterial and antifungal activities. The source of Maximin 2 is Bombina maxima [Giant fire-bellied toad].
Maximin 28
Maximin 28 has antibacterial and antifungal activities. The source of Maximin 28 is Bombina maxima [Giant fire-bellied toad].
Maximin 3
Maximin 3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. It also shows antimicrobial activity against the fungus C.albicans, but not against A.flavus nor P.uticale. It has little hemolytic activity. Maximin 3 possesses a significant cytotoxicity against tumor cell lines and possesses a significant anti-HIV activity. It also shows high spermicidal activity.
Maximin 31
Maximin 31 has antibacterial and antifungal activities. The source of Maximin 31 is Bombina maxima [Giant fire-bellied toad].
Maximin 32
Maximin 32 has antibacterial and antifungal activities. The source of Maximin 32 is Bombina maxima [Giant fire-bellied toad].
Maximin 39
Maximin 39 has antibacterial and antifungal activities. The source of Maximin 39 is Bombina maxima [Giant fire-bellied toad].
Maximin 4
Maximin 4 has antibacterial, antifungal and antiviral activities. The source of Maximin 4 is Chinese red belly toad, Bombina maxima, Yunnan, China, Asia. It is active against E. coli ATCC25922, S. aureus ATCC2592, B. pyocyaneus CMCCB10104, B. megatherium, B. dysenterium, K. pneumoniae, and C. albicans ATCC2002 (MIC 1.5-15 μM). Synonyms: H-Gly-Ile-Gly-Gly-Val-Leu-Leu-Ser-Ala-Gly-Lys-Ala-Ala-Leu-Lys-Gly-Leu-Ala-Lys-Val-Leu-Ala-Glu-Lys-Tyr-Ala-Asn-OH. Grades: >96% by HPLC. Molecular formula: C119H206N32O33. Mole weight: 2613.09.
Maximin 41
Maximin 41 has antibacterial and antifungal activities. The source of Maximin 41 is Bombina maxima [Giant fire-bellied toad].
Maximin 42
Maximin 42 has antibacterial and antifungal activities. The source of Maximin 42 is Bombina maxima [Giant fire-bellied toad]. Grades: >95% by HPLC.
Maximin 45
Maximin 45 has antibacterial and antifungal activities. The source of Maximin 45 is Bombina maxima [Giant fire-bellied toad].
Maximin 49
Maximin 49 has Antibacterial, Antifungal activity. Maximin 49 was found in brain, Bombina maxima, China, Asia.
Maximin 5
Maximin 5 shows antibacterial activity against both Gram-positive and Gram-negative bacteria. The only exception is the resistance of E.coli. It also shows antimicrobial activity against fungi C.albicans, A.flavus and P.uticale. It has little hemolytic activity.
Maximin 63
Maximin 63 has antibacterial and antifungal activities. The source of Maximin 63 is Bombina maxima [Giant fire-bellied toad].
Maximin 68
Maximin 68 has antibacterial and antifungal activities. The source of Maximin 68 is Bombina maxima [Giant fire-bellied toad].
Maximin-7
The source of Maximin 7 is Chinese red belly toad, Bombina maxima, Yunnan, China, Asia. Maximin 7 shows antimicrobial activity against bacteria and against the fungus C.albicans. It has little hemolytic activity. Molecular formula: C89H155N23O25. Mole weight: 1947.32.