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| Product | Description | |
|---|---|---|
| MC-Gly-Gly-Phe-Gly-PAB-MMAE | MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055607-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132134. |  |
| MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan | MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-A1811 Drug-linker. CAS No. 2414254-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148668. | |
| MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan | MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414254-52-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148668A. | |
| MCH (human, mouse, rat) | MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Synonyms: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grade: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84. |  |
| MCH (human, mouse, rat) | MCH (human, mouse, rat). Group: Biochemicals. Grades: Purified. CAS No. 128315-56-0. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| m-Chloro Hippuric Acid | m-Chloro Hippuric Acid. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid; N-(3-Chlorobenzoyl)glycine; NSC 201882; m-Chlorohippuric Acid; N-(3-Chlorobenzoyl)glycine. Grades: Highly Purified. CAS No. 57728-59-3. Pack Sizes: 1g. Molecular Formula: C9H8ClNO3, Molecular Weight: 218.62. US Biological Life Sciences. | Worldwide |
| m-Chloro Hippuric Acid-d2,15N | m-Chloro Hippuric Acid-d2,15N. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid-d2,15N; N-(3-Chlorobenzoyl)glycine-d2,15N; NSC 201882-d2,15N; m-Chlorohippuric Acid-d2,15N; N-(3-Chlorobenzoyl)glycine-d2,15N. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C9H6D2Cl15NO3, Molecular Weight: 216.62. US Biological Life Sciences. | Worldwide |
| m-Chlorophenylbiguanide hydrochloride | m-Chlorophenylbiguanide hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2113-5-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| MCI-INI-3 | MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3 (with a Ki value of 0.55 μM for ALDH1A3 and a Ki value of 78.2 μM for ALDH1A1). MCIINI-3 inhibits the biosynthesis of retinoic acid and reduces the viability of GSC-83 and GSC-326 glioblastoma cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1011366-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-169884. | |
| MCL 0020 | MCL 0020. Group: Biochemicals. Grades: Purified. CAS No. 475498-26-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MCL 0020 | MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Synonyms: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grade: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73. | |
| MCL-1/BCL-2-IN-1 | MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 4.45 and 3.18 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493256-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129681. | |
| Mcl-1 inhibitor 6 | Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a Kd of 0.23 nM and a Ki of 0.02 μM. Mcl-1 inhibitor 6 possesses superior selectivity over other Bcl-2 family members (Bcl-2, Bcl2A1, Bcl-xL, and Bcl-w, Kd>10 μM). Mcl-1 inhibitor 6 is a potent antitumor agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2598978-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132307. | |
| Mcl-1 Inhibitor, MIM1 (4-((E)-((Z)-2-(cyclohexylimino)-4-methylthiazol-3(2H)-ylimino)methyl)benzene-1,2,3-triol, Mcl-1 Inhibitor Molecule 1) | A cell-permeable thiazolyl iminopyrogallol that selectively neutralizes Mcl-1, but not Bcl-XL, antiapoptotic activity by directly targeting Mcl-1 BH3-binding site, effectively competing against Bid BH3 sequence for Mcl-1 binding (IC50 = 4.8uM). Shown to induce caspase 3/7 activation and cell death in Mcl-1-, but not Bcl-XL-, dependent B-ALL cultures (6% vs. 82% survival, respectively; 10uM). In comparison, ABT-737 affects only Bcl-XL-, but not Mcl-1-, dependent B-ALL cells. Neither MIM1 nor ABT-737 significantly affects the survival of wild-type or Bax-/-Bak-/- MEF. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| MCM-22 | MCM-22. CAS No. 12173-28-3. |  |
| MCM-41 | MCM-41. | |
| MCM-41 | MCM-41. CAS No. 12173-28-3. | |
| Mc-MMAD | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. Uses: Adcs cytotoxin-linker. Synonyms: Mc MMAD; McMMAD. Grade: >98%. CAS No. 1401963-15-2. Molecular formula: C51H77N7O9S. Mole weight: 964.26. | |
| Mc-MMAE | Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Synonyms: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grade: ≥98%. CAS No. 863971-24-8. Molecular formula: C49H78N6O10. Mole weight: 911.18. | |
| Mc-MMAE | Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-monomethylauristatin E. CAS No. 863971-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15741. | |
| McMMAF | McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl monomethylauristatin F. CAS No. 863971-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15578. | |
| Mc-MMAF | Mc-MMAF is a protective group-conjugated MMAF, MMAF is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin and it has lower cytotoxic activity than MMAE. Uses: Sgd 1269 is a potent tubulin inhibitor and is a toxin payload in antibody drug conjugate. it is a useful agent for make antibody drug conjugate (adc) for targeted drug delivery. Synonyms: SGD-1269; SGD 1269; SGD1269; mc-MMAF; mcMMAF; L4-MMAF; Maleimidocaproyl-MMAF; Maleimidocaproyl monomethylauristatin F; Mafodotin.((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grade: ≥98%. CAS No. 863971-19-1. Molecular formula: C49H76N6O11. Mole weight: 925.18. | |
| McN3716 | McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl palmoxirate; NSC359682. CAS No. 69207-52-9. Pack Sizes: 1 mg. Product ID: HY-U00159. | |
| McN-A 343 | McN-A 343. Group: Biochemicals. Grades: Purified. CAS No. 55-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MCOPPB trihydrochloride | MCOPPB trihydrochloride is a nociceptin receptor agonist with pKi of 10. Uses: Scientific research. Category: Signaling pathways. CAS No. 1108147-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13101. | |
| MCOPPB Trihydrochloride | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. Group: Biochemicals. Alternative Names: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059. Grades: Highly Purified. CAS No. 1108147-88-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mcpa-1-Butyl Ester | Mcpa-1-Butyl Ester. Alternative Names: ((4-chloro-o-tolyl)oxy)-aceticacibutylester;(4-chloro-2-methylphenoxy)-aceticacibutylester;2-methyl-4-chlorophenoxyaceticacidn-butylester;butyl2-methyl-4-chlorophenoxyacetate;butyl4-chloro-o-tolyloxyacetate;mcpa,butylester;mcpabutyl;mcpbutylester. CAS No. 1713-12-8. Product ID: ACM1713128. Molecular formula: C13H17ClO3. Mole weight: 256.72528. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| MCPA-d3 | MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352431-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0859S1. | |
| MCPA-[d3] | MCPA-[d3]. Synonyms: MCPA D3; (4-Chloro-2-methylphenoxy-2,?3,?5-d3)?acetic Acid. Grade: 98% atom D. CAS No. 352431-14-2. Molecular formula: C9H6D3ClO3. Mole weight: 203.64. | |
| m-CPBG hydrochloride | m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(3-Chlorophenyl)biguanide hydrochloride. CAS No. 2113-5-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-100938. | |
| MCP(Modified Citrus Pectin) | MCP(Modified Citrus Pectin). Categories: ore. |  CA, FL & NJ |
| Mc-Pro-PAB-MMAE | Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766450-03-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171060. | |
| m-Cresol | 500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-500g. Molecular Weight 108.14. See USA prepack pricing. |  |
| m-Cresol | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-100g. Molecular Weight 108.14. See USA prepack pricing. | |
| m-Cresol | m-Cresol. CAS No. 108-39-4. Purity: 0.995. Product ID: ALC-FP-108394. Alfa Chemistry - ISO 9001:32057 Certified. | |
| M-Cresol | M-Cresol. Group: Biochemicals. Grades: Highly Purified. CAS No. 108-39-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H8O. US Biological Life Sciences. | Worldwide |
| m-Cresol-[d7] | m-Cresol-[d7]. Synonyms: m-Cresol D7; 3-Methylphenol-d7; 1-Hydroxy-3-methylbenzene-d7; 3-Hydroxytoluene-d7. Grade: 95% atom D. CAS No. 202325-51-7. Molecular formula: C7HD7O. Mole weight: 115.18. | |
| m-Cresol-[d8] | m-Cresol-[d8]. Synonyms: 3-Methylphenol-d8. Grade: 98% by CP; 98% atom D. CAS No. 302911-90-6. Molecular formula: C7D8O. Mole weight: 116.19. | |
| m-Cresol-[methyl-d3] | m-Cresol-[methyl-d3]. Synonyms: m-Cresol-d3 (methyl-d3); 3-(Methyl-d3)-phenol. Grade: 98% atom D. CAS No. 25026-32-8. Molecular formula: C7H5D3O. Mole weight: 111.16. | |
| m-CRESOXYACETIC ACID | m-CRESOXYACETIC ACID. Alternative Names: m-Methylphenoxyacetic acid, m-Toloxyacetic acid, (3-Methylphenoxy)acetic acid, 3-Methylphenoxyacetic acid, Acetic acid, (m-tolyloxy)-, m-CRESOXYACETIC ACID, Acetic acid, (3-methylphenoxy)-, ARONIS015558, EINECS 216-698-7, NSC 35913, AIDS017836, BB_SC-3069, AIDS-017836, ALBB-000801, CID74235, NSC35913, BRN 2047572, STK411995, LS-12511, 4-06-00-02051 (Beilstein Handbook Reference). CAS No. 1643-15-8. Purity: 96%. Product ID: ACM1643158. Molecular formula: C9H10O3. Mole weight: 166.18. IUPAC Name: 2-(3-methylphenoxy)acetic acid. ECNumber: 216-698-7. Alfa Chemistry - ISO 9001:32057 Certified. | |
| MC-SN38 | MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1473403-87-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136170. | |
| MCT1-IN-2 | MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 227321-12-2. Pack Sizes: 5 mg. Product ID: HY-18974. | |
| MCT-IN-1 | MCT-IN-1 (Compound 2) is a potent MCT inhibitor, with IC50 values of 9 nM and 14 nM against MCT1 and MCT4, respectively. MCT-IN-1 can be used in research related to solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1685273-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150314. | |
| MCT - Medium Chain Triglyceride | MCT - Medium Chain Triglyceride (Caprylic / Capric Triglyceride). CAS No. 73398-61-5. Kosher: Y. VIGON Item # 507177. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essetial Oils. |  America & Internationally |
| MCT-ND6 | MCT-ND6 showed complete agonism compared with FPR1 agonist and FPR2 agonist. Grade: ≥95%. CAS No. 863418-59-1. Molecular formula: C38H54N6O9S2. Mole weight: 802.98. | |
| m-C-tri(CH2-PEG1-NHS ester) | m-C-tri(CH2-PEG1-NHS ester) signifies a multifaceted and utilitarian agent extensively employed within the realm of biomedicine. Its profound versatility lies in its adeptness as a reactive entity, facilitating the intricate conjugation of pharmaceuticals or biomolecular entities to meticulously designated targets. Synonyms: bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(2-((3-(2,5-dioxopyrrolidin-1-yloxy)-3-oxopropoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy)dipropanoate; 3,3',3''-[Ethylidynetris(methyleneoxy)]tris(propionic acid succinimidyl) ester. Grade: 98%. CAS No. 173414-89-6. Molecular formula: C26H33N3O15. Mole weight: 627.55. | |
| MCU-i11 | MCU-i11 is a negative regulator of the mitochondrial calcium uniporter (MCU) complex. MCU-i11 can reduce mitochondrial Ca2+ uptake. MCU-i11 impairs muscle cell growth. MCU-i11 can be used to study breast cancer, cervical cancer and neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902903-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W194810. | |
| MCU-i4 | MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 371924-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138620. | |
| MC-Val-Ala-OH | MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1342211-31-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-101153. | |
| Mc-?Val-?Ala-?PAB | Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1870916-87-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126364. | |
| MC-Val-Ala-PAB-PNP | MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639939-40-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-135975. | |
| MC-Val-Cit-PAB | MC-Val-Cit-PAB is a cleavable ADC Linker that forms part of VcMMAE (HY-15575). VcMMAE is Drug-Linker Conjugates for ADCs. The ADC Cytotoxin in VcMMAE is MMAE, a tubulin polymerization inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 159857-80-4. Pack Sizes: 5 mg; 10 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-78738. | |
| Mc-Val-Cit-PAB-Cl | Mc-Val-Cit-PAB-Cl. Synonyms: N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(chloromethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide. CAS No. 1639351-92-0. Molecular formula: C28H39ClN6O6. Mole weight: 591.1. | |
| Mc-Val-Cit-PAB-Cl | Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1639351-92-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112099. | |
| Mc-Val-Cit-PABC-PNP | Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate. CAS No. 159857-81-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-20336. | |
| Mc-Val-Cit-PABC-PNP | Mc-Val-Cit-PABC-PNP. Uses: Adcs linker. Synonyms: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonateMc-Val-Cit-PABC-PNP159857-81-5MC-Val-Cit-PAB-PNPSCHEMBL3205376HYSPJPGXSALJRR-DHIFEGFHSA-NC3. Grade: >98%. CAS No. 159857-81-5. Molecular formula: C35H43N7O11. Mole weight: 737.76. | |
| MC-Val-Cit-PAB-duocarmycin chloride | MC-Val-Cit-PAB-duocarmycin chloride is a agent-linker conjugate for ADC with potent antitumor activity by using Duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128904. | |
| MC-Val-Cit-PAB-Exatecan | MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-Val-Cit-PAB-DX8951. CAS No. 2504068-28-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145929. | |
| MC-Val-Cit-PAB-Indibulin | MC-Val-Cit-PAB-Indibulin is a agent-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-95-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128908. | |
| MC-Val-Cit-PAB-Ispinesib | MC-Val-Cit-PAB-Ispinesib (Compound 509) is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker and Eg5 inhibitor. MC-Val-Cit-PAB-Ispinesib can be used for the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629737-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160441. | |
| MC-Val-Cit-PAB-MMAE | MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Synonyms: VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Vedotin. Grade: 95%. CAS No. 646502-53-6. Molecular formula: C68H105N11O15. Mole weight: 1316.63. | |
| MC-Val-Cit-PAB-MMAF | MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB-MMAF shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vc-MMAF. CAS No. 863971-17-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112786. | |
| MC-Val-Cit-PAB-MMAF | MC-Val-Cit-PAB-MMAF is a potent tubulin inhibitor (MMAF), Val-Cit-PAB-MMAF is an antibody drug conjugate. Synonyms: MC-VC-PAB-MMAF. Grade: ≥98%. CAS No. 863971-17-9. Molecular formula: C68H103N11O16. Mole weight: 1330.6. | |
| MC-Val-Cit-PAB-vinblastine | MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128902. | |
| MC-Val-D-Cit-PAB-PNP | MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 1350456-66-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-147021. | |
| MC-VA-PABC-MMAE | MC-VA-PABC-MMAE is a agent-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1818864-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147239. | |
| MC-VA-PAB-Exatecan | MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2680543-57-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147270. | |
| MC-VC-PABC-amide-PEG1-CH2-CC-885 | MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722697-82-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145448. | |
| MC-VC-PABC-Aur0101 | MC-VC-PABC-Aur0101 is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC. Uses: Scientific research. Category: Signaling pathways. CAS No. 1438849-92-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128955. | |
| MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1616727-21-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136132A. | |
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