A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1473403-87-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136170.
MCT1-IN-2
MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 227321-12-2. Pack Sizes: 5 mg. Product ID: HY-18974.
MCT-IN-1
MCT-IN-1 (Compound 2) is a potent MCT inhibitor, with IC50 values of 9 nM and 14 nM against MCT1 and MCT4, respectively. MCT-IN-1 can be used in research related to solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1685273-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150314.
MCT - Medium Chain Triglyceride
MCT - Medium Chain Triglyceride (Caprylic / Capric Triglyceride). CAS No. 73398-61-5. Kosher: Y. VIGON Item # 507177. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essetial Oils.
America & Internationally
MCT-ND6
MCT-ND6 showed complete agonism compared with FPR1 agonist and FPR2 agonist. Grade: ≥95%. CAS No. 863418-59-1. Molecular formula: C38H54N6O9S2. Mole weight: 802.98.
m-C-tri(CH2-PEG1-NHS ester)
m-C-tri(CH2-PEG1-NHS ester) signifies a multifaceted and utilitarian agent extensively employed within the realm of biomedicine. Its profound versatility lies in its adeptness as a reactive entity, facilitating the intricate conjugation of pharmaceuticals or biomolecular entities to meticulously designated targets. Synonyms: bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(2-((3-(2,5-dioxopyrrolidin-1-yloxy)-3-oxopropoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy)dipropanoate; 3,3',3''-[Ethylidynetris(methyleneoxy)]tris(propionic acid succinimidyl) ester. Grade: 98%. CAS No. 173414-89-6. Molecular formula: C26H33N3O15. Mole weight: 627.55.
MCU-i11
MCU-i11 is a negative regulator of the mitochondrial calcium uniporter (MCU) complex. MCU-i11 can reduce mitochondrial Ca2+ uptake. MCU-i11 impairs muscle cell growth. MCU-i11 can be used to study breast cancer, cervical cancer and neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902903-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W194810.
MCU-i4
MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 371924-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138620.
MC-Val-Ala-OH
MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1342211-31-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-101153.
Mc-?Val-?Ala-?PAB
Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1870916-87-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126364.
MC-Val-Ala-PAB-PNP
MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639939-40-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-135975.
MC-Val-Cit-PAB
MC-Val-Cit-PAB is a cleavable ADC Linker that forms part of VcMMAE (HY-15575). VcMMAE is Drug-Linker Conjugates for ADCs. The ADC Cytotoxin in VcMMAE is MMAE, a tubulin polymerization inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 159857-80-4. Pack Sizes: 5 mg; 10 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-78738.
Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1639351-92-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112099.
Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate. CAS No. 159857-81-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-20336.
MC-Val-Cit-PAB-duocarmycin chloride is a agent-linker conjugate for ADC with potent antitumor activity by using Duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128904.
MC-Val-Cit-PAB-Exatecan
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-Val-Cit-PAB-DX8951. CAS No. 2504068-28-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145929.
MC-Val-Cit-PAB-Indibulin
MC-Val-Cit-PAB-Indibulin is a agent-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-95-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128908.
MC-Val-Cit-PAB-Ispinesib
MC-Val-Cit-PAB-Ispinesib (Compound 509) is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker and Eg5 inhibitor. MC-Val-Cit-PAB-Ispinesib can be used for the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629737-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160441.
MC-Val-Cit-PAB-MMAE
MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Synonyms: VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Vedotin. Grade: 95%. CAS No. 646502-53-6. Molecular formula: C68H105N11O15. Mole weight: 1316.63.
MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF is a potent tubulin inhibitor (MMAF), Val-Cit-PAB-MMAF is an antibody drug conjugate. Synonyms: MC-VC-PAB-MMAF. Grade: ≥98%. CAS No. 863971-17-9. Molecular formula: C68H103N11O16. Mole weight: 1330.6.
MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB-MMAF shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vc-MMAF. CAS No. 863971-17-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112786.
MC-Val-Cit-PAB-vinblastine
MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128902.
MC-Val-D-Cit-PAB-PNP
MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 1350456-66-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-147021.
MC-VA-PABC-MMAE
MC-VA-PABC-MMAE is a agent-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1818864-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147239.
MC-VA-PAB-Exatecan
MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2680543-57-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147270.
MC-VC-PABC-amide-PEG1-CH2-CC-885
MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722697-82-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145448.
MC-VC-PABC-Aur0101
MC-VC-PABC-Aur0101 is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC. Uses: Scientific research. Category: Signaling pathways. CAS No. 1438849-92-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128955.
MC-VC-PAB-NH2 TFA
MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1616727-21-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136132A.
MC-VC-PAB-O-Gemcitabine
MC-VC-PAB-O-Gemcitabine is a linker-antibiotic intermediate, which is part of the antibody-antibiotic conjugate (AAC) molecule. MC-VC-PAB-O-Gemcitabine is conjugated with the linker and the antibiotic Gemcitabine (HY-17026). MC-VC-PAB-O-Gemcitabine can be used to study the immunotherapy of bacterial infections and the development of new antibacterial drugs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639430-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171414.
Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801838-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131057.
MC-VC-PAB-Tubulysin M
MC-vc-PAB-Tubulysin M is a Drug-Linker Conjugates for ADC, consisting of a microtubule polymerization inhibitor Tubulysin M (an ADC cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639939-56-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136313.
m-Cyanobenzyl chloride
m-Cyanobenzyl chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 64407-07-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
MD-222
MD-222 is the first-in-class highly potent PROTAC degrader of MDM2. MD-222 consists of ligands for Cereblon and MDM2. MD-222 induces rapid degradation of the MDM2 protein and activation of wild-type p53 in cells. MD-222 has anticancer effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2136246-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-134823.
MD-224
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 consists of ligands for Cereblon and MDM2. MD-224 induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells, and achieves an IC50 value of 1.5 nM in inhibition of growth of RS4;11 cells. MD-224 has the potential to be a new class of anticancer agent[1]. MD-224 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2136247-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-114312.
MD2-TLR4-IN-1
MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex antagonist. MD2-TLR4-IN-1 inhibits Lipopolysaccharides (HY-D1056) (LPS)-induced expression of TNF-α and IL-6 in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. MD2-TLR4-IN-1 can be used for the study of acute lung injury (ALI)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2249801-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128598.
MDA-MB Transfection Reagent
Transfection Reagent for MDA-MB Breast Adenocarcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1794.
Cell-permeable. An irreversible inhibitor of p97 (IC50 <10uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1485-00-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Transfection Reagent for MDCK Kidney Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6846.
Nevada, Texas, USA
MDEPAP
MDEPAP. Uses: For analytical and research use. Alternative Names: 1-Methyl-4-(4-diethylaminophenylazo)pyridinium Iodide. CAS No. 74920-80-2. Molecular formula: C16H21IN4. Mole weight: 396.28. Purity: >95.0%(HPLC)(N). Catalog: APB74920802.
MDH1/2-IN-1
MDH1/2-IN-1 is a MDH1/2 inhibitor (IC50: 1.07 μM and 1.06 μM respectively). MDH1/2-IN-1 inhibits mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 demonstrates significant anti-tumor potential. MDH1/2-IN-1 provides a new direction for the development of drugs targeting cancer metabolism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143473-95-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W613220.
MDH1-IN-1
MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143463-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147790.
MDH1-IN-2
MDH1-IN-2 (Compound 7c) is a selective MDH1 inhibitor, with IC50 values of 2.27 and 27.47 μM for MDH1 and MDH2, respectively. MDH1-IN-2 can reduce the generation of ROS by inhibiting the conversion of 2-Ketoglutaric acid (HY-W013636) to α-Hydroxyglutaric acid (HY-113038B) mediated by MDH1, thereby suppressing 2-Ketoglutaric acid (HY-W013636)-induced ferroptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143463-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147791.
MDI-2268
MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1609176-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124577.
Mdivi 1
Mdivi 1. Group: Biochemicals. Grades: Purified. CAS No. 338967-87-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Mdivi-1
Mdivi-1 is a selective dynamin-related protein 1 (Drp1) inhibitor. Mdivi-1 is a mitochondrial division/mitophagy inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15886.
Mdivi-1
Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis. Group: Inhibitors. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 20mg. Product ID: S7162. Formula: C15H10Cl2N2O2S. Smiles: COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl. Storage Conditions: 2 years -80 in solvent.
MDL 100907. Group: Biochemicals. Grades: Purified. CAS No. 139290-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MDL 105519
MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor. Uses: Scientific research. Category: Signaling pathways. CAS No. 161230-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15085.
MDL 11,939
MDL 11,939. Group: Biochemicals. Grades: Purified. CAS No. 107703-78-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MDL12330A
MDL12330A (RMI12330A) is an adenylyl cyclases inhibitor. MDL12330A can inhibit KV channels, increases insulin secretion and Ca2+ levels. MDL12330A accentuates contractions in uterine rings and inhibits cardiac functions. MDL12330A can be used for the research of endocrinology, metabolic and cardiovascular disease [1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RMI12330A. CAS No. 40297-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103192.
MDL 12330A hydrochloride
MDL 12330A hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 40297-09-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MDL 28170
MDL 28170. Group: Biochemicals. Alternative Names: [ (1S) -1-[[ (1-Formyl-2-phenylethyl) amino]carbonyl]-2-methylpropyl]carbamic Acid Phenylmethyl Ester; Calp III; Calpain Inhibitor III. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 25mg. Molecular Formula: C22H26N2O4, Molecular Weight: 382.45. US Biological Life Sciences.
Worldwide
MDL 28170
MDL 28170 is a calpain and cathepsin B inhibitor with Ki values of 10 and 25 nM respectively. It shows neuroprotective effects in vivo. MDL 28170 can attenuate depression in myocardial contractile performance which occurs during reperfusion following cardiac ischemia. Synonyms: benzyl N-[(2S)-3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate. Grade: ≥ 95 % by HPLC. CAS No. 88191-84-8. Molecular formula: C22H26N2O4. Mole weight: 382.45.
MDL-28170
MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration[1][2]. MDL-28170 also block γ-secretase[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calpain Inhibitor III. CAS No. 88191-84-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18236.
A potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25nm respectively). MDL 28170 does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Modulates the formation of Ab formation by inhibiting the formation of intermediate Ab46 and protecting Ab from degradation. Group: Biochemicals. Grades: Highly Purified. CAS No. 88191-84-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MDL 29913
MDL 29913 is a selective NK2 tachykinin receptor antagonist which can be used in the treatment of IBS. Synonyms: MDL 29913; MDL29913; MDL-29913; 1,4,7,10,13,16-Hexaazacyclooctadecane, Cyclic Peptide Deriv.; N-(2-Amino-4-methylpentyl)?-N-methyl-L-leucyl-L-glutaminyl-L-tryptophyl-L-phenylalanylglycine (5→1)?-Lactam. Grade: >97%. CAS No. 135721-56-1. Molecular formula: C40H56N8O6. Mole weight: 744.92.
MDL 29951
MDL 29951. Group: Biochemicals. Alternative Names: 2-Carboxy-4,6-dichloro-1H-Indole-3-propanoic Acid. Grades: Highly Purified. CAS No. 130798-51-5. Pack Sizes: 250mg. Molecular Formula: C12H9Cl2NO4, Molecular Weight: 302.11. US Biological Life Sciences.
Worldwide
MDL-29951
MDL-29951 is a novel glycine antagonist of NMDA receptor activation, with Ki of 0.14 μM for [3H]glycine binding in vitro and in vivo. Uses: Scientific research. Category: Signaling pathways. CAS No. 130798-51-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16312.
MDL 72222
MDL 72222. Group: Biochemicals. Grades: Purified. CAS No. 40796-97-2. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
MDL 72527
MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 93565-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100621.