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| Product | Description | |
|---|---|---|
| MCOPPB trihydrochloride | MCOPPB trihydrochloride is a nociceptin receptor agonist with pKi of 10. Uses: Scientific research. Category: Signaling pathways. CAS No. 1108147-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13101. |  |
| MCOPPB triHydrochloride | The trihydrochloride salt form of MCOPPB, an effective full agonist of nociceptin receptor, could be a good antianxiety agent with few side-effects. pKi: 10.07. Uses: The trihydrochloride salt form of mcoppb could be a good antianxiety agent with few side-effects. Alternative Names: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole;trihydrochloride;MCOPPBtrihydrochloride;1028969-49-4;1108147-88-1;1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-Benzimidazoletrihydrochloride. Grades: 95%. CAS No. 1108147-88-1. Molecular formula: C26H40N4.3HCL. Mole weight: 518.01. |  |
| MCOPPB Trihydrochloride | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. Group: Biochemicals. Alternative Names: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059. Grades: Highly Purified. CAS No. 1108147-88-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| MCP110 | MCP110 is a Ras/Raf-1 interaction inhibitor. The Ras signaling pathway is activated either by direct mutation of Ras or its effector B-Raf. MCP110 was shown to inhibit proliferation of tumor cells. Alternative Names: MCP110; MCP-110; MCP 110; N-(4-(benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide. CAS No. 521310-51-0. Molecular formula: C33H36N2O3. Mole weight: 508.662. | |
| Mcpa-1-Butyl Ester | Mcpa-1-Butyl Ester. Alternative Names: ((4-chloro-o-tolyl)oxy)-aceticacibutylester;(4-chloro-2-methylphenoxy)-aceticacibutylester;2-methyl-4-chlorophenoxyaceticacidn-butylester;butyl2-methyl-4-chlorophenoxyacetate;butyl4-chloro-o-tolyloxyacetate;mcpa,butylester;mcpabutyl;mcpbutylester. CAS No. 1713-12-8. Product ID: ACM1713128. Molecular formula: C13H17ClO3. Mole weight: 256.72528. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| MCPA-d3 | MCPA-d3 is the deuterium labeled MCPA (HY-B0859). MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 352431-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0859S1. | |
| MCPA-[d6] | MCPA-[d6]. CAS No. 2733716-88-4. | |
| m-CPBG hydrochloride | m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(3-Chlorophenyl)biguanide hydrochloride. CAS No. 2113-5-5. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g. Product ID: HY-100938. | |
| MCP(Modified Citrus Pectin) | MCP(Modified Citrus Pectin). Categories: ore. |  CA, FL & NJ |
| Mc-Pro-PAB-MMAE | Mc-Pro-PAB-MMAE is a Drug-Linker Conjugate for ADC. Mc-Pro-PAB-MMAE consists of Monomethyl auristatin E (HY-15162) and a linker. Mc-Pro-PAB-MMAE can be used for synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766450-03-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171060. | |
| m-Cresol | m-Cresol. CAS No. 108-39-4. Purity: 0.995. Product ID: ALC-FP-108394. Alfa Chemistry - ISO 9001:32057 Certified. | |
| m-Cresol | 500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-500g. Molecular Weight 108.14. See USA prepack pricing. |  |
| m-Cresol | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C7H8O. CAS No. 108-39-4. Prepack ID 38451247-100g. Molecular Weight 108.14. See USA prepack pricing. | |
| M-Cresol | M-Cresol. Group: Biochemicals. Grades: Highly Purified. CAS No. 108-39-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H8O. US Biological Life Sciences. | Worldwide |
| m-Cresol sulfonic acid | m-Cresol sulfonic acid. CAS No. 69103-65-7. Molecular formula: C7H8O4S. Mole weight: 188.20. | |
| m-CRESOXYACETIC ACID | m-CRESOXYACETIC ACID. Alternative Names: m-Methylphenoxyacetic acid, m-Toloxyacetic acid, (3-Methylphenoxy)acetic acid, 3-Methylphenoxyacetic acid, Acetic acid, (m-tolyloxy)-, m-CRESOXYACETIC ACID, Acetic acid, (3-methylphenoxy)-, ARONIS015558, EINECS 216-698-7, NSC 35913, AIDS017836, BB_SC-3069, AIDS-017836, ALBB-000801, CID74235, NSC35913, BRN 2047572, STK411995, LS-12511, 4-06-00-02051 (Beilstein Handbook Reference). CAS No. 1643-15-8. Purity: 96%. Product ID: ACM1643158. Molecular formula: C9H10O3. Mole weight: 166.18. IUPAC Name: 2-(3-methylphenoxy)acetic acid. ECNumber: 216-698-7. Alfa Chemistry - ISO 9001:32057 Certified. | |
| MC-SN38 | MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1473403-87-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136170. | |
| MCT1-IN-2 | MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 227321-12-2. Pack Sizes: 5 mg. Product ID: HY-18974. | |
| MCT-IN-1 | MCT-IN-1 (Compound 2) is a potent MCT inhibitor, with IC50 values of 9 nM and 14 nM against MCT1 and MCT4, respectively. MCT-IN-1 can be used in research related to solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1685273-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150314. | |
| MCT - Medium Chain Triglyceride | MCT - Medium Chain Triglyceride (Caprylic / Capric Triglyceride). CAS No. 73398-61-5. Kosher: Y. VIGON Item # 507177. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essetial Oils. |  America & Internationally |
| MCT-ND6 | MCT-ND6 showed complete agonism compared with FPR1 agonist and FPR2 agonist. Grades: ≥95%. CAS No. 863418-59-1. Molecular formula: C38H54N6O9S2. Mole weight: 802.98. | |
| m-C-tri(CH2-PEG1-NHS ester) | m-C-tri(CH2-PEG1-NHS ester) signifies a multifaceted and utilitarian agent extensively employed within the realm of biomedicine. Its profound versatility lies in its adeptness as a reactive entity, facilitating the intricate conjugation of pharmaceuticals or biomolecular entities to meticulously designated targets. Alternative Names: bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(2-((3-(2,5-dioxopyrrolidin-1-yloxy)-3-oxopropoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy)dipropanoate; 3,3',3''-[Ethylidynetris(methyleneoxy)]tris(propionic acid succinimidyl) ester. Grades: 98%. CAS No. 173414-89-6. Molecular formula: C26H33N3O15. Mole weight: 627.55. | |
| MCU-i11 | MCU-i11 is a negative regulator of the mitochondrial calcium uniporter (MCU) complex. MCU-i11 can reduce mitochondrial Ca2+ uptake. MCU-i11 impairs muscle cell growth. MCU-i11 can be used to study breast cancer, cervical cancer and neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902903-59-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-W194810. | |
| MCU-i4 | MCU-i4 is a negative modulator of the mitochondrial calcium uniporter (MCU) complex, which directly binds a specific cleft in MICU1 and decreases mitochondrial Ca2+ influx. Alternative Names: Ethyl 4-((4-(diethylamino)phenyl)amino)-6-methylquinoline-3-carboxylate. CAS No. 371924-24-2. Molecular formula: C23H27N3O2. Mole weight: 377.48. | |
| MCU-i4 | MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 371924-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138620. | |
| MC-Val-Ala-OH | MC-Val-Ala-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1342211-31-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-101153. | |
| Mc-?Val-?Ala-?PAB | Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. CAS No. 1870916-87-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126364. | |
| MC-Val-Ala-PAB-PNP | MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639939-40-4. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-135975. | |
| MC-Val-Ala-PBD | MC-Val-Ala-PBD is a protective group conjugated PBD, PBD bind in the minor groove of DNA. Alternative Names: L-Alaninamide, N-(6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl)-L-valyl-N-(4-((11aS)-8-(3-(((11aS)-5,11a-dihydro-7-methoxy-2-(4-methoxyphenyl)-5-oxo-1H-pyrrolo(2,1-C)(1,4)benzodiazepin-8-yl)oxy)propoxy)-5,11a-dihydro-7-methoxy-5-oxo-1H-pyrrolo. Grades: ≥98%. CAS No. 1342820-51-2. Molecular formula: C60H64N8O12. Mole weight: 1089.20. | |
| MC-Val-Cit-PAB | MC-Val-Cit-PAB. Alternative Names: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-; N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide; 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino]-1-oxo-5-ureidopentan-2-yl)amino]-3-methyl-1-oxobutan-2-yl)hexanamide; N-[(1S)-1-[[(1S)-4-(carbamoylamino)-1-[[4-(hydroxymethyl)phenyl]carbamoyl]butyl]carbamoyl]-2-methylpropyl]-6-(2,5-dioxopyrrol-1-yl)hexanamide. Grades: ≥95%. CAS No. 159857-80-4. Molecular formula: C28H40N6O7. Mole weight: 572.65. | |
| MC-Val-Cit-PAB | MC-Val-Cit-PAB is a cleavable ADC Linker that forms part of VcMMAE (HY-15575). VcMMAE is Drug-Linker Conjugates for ADCs. The ADC Cytotoxin in VcMMAE is MMAE, a tubulin polymerization inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 159857-80-4. Pack Sizes: 5 mg; 10 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-78738. | |
| Mc-Val-Cit-PAB-Cl | Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1639351-92-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112099. | |
| Mc-Val-Cit-PAB-Cl | Mc-Val-Cit-PAB-Cl. Alternative Names: N-[(2S)-1-[[(2S)-5-(carbamoylamino)-1-[4-(chloromethyl)anilino]-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-6-(2,5-dioxopyrrol-1-yl)hexanamide. CAS No. 1639351-92-0. Molecular formula: C28H39ClN6O6. Mole weight: 591.1. | |
| Mc-Val-Cit-PABC-PNP | Mc-Val-Cit-PABC-PNP. Uses: Adcs linker. Alternative Names: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonateMc-Val-Cit-PABC-PNP159857-81-5MC-Val-Cit-PAB-PNPSCHEMBL3205376HYSPJPGXSALJRR-DHIFEGFHSA-NC3. Grades: >98%. CAS No. 159857-81-5. Molecular formula: C35H43N7O11. Mole weight: 737.76. | |
| Mc-Val-Cit-PABC-PNP | Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate. CAS No. 159857-81-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-20336. | |
| MC-Val-Cit-PAB-duocarmycin | MC-Val-Cit-PAB-duocarmycin is a drug-linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. Alternative Names: MC Val Cit PAB duocarmycin. CAS No. 2055896-98-3. Molecular formula: C54H65ClN9O9. Mole weight: 1019.6. | |
| MC-Val-Cit-PAB-duocarmycin chloride | MC-Val-Cit-PAB-duocarmycin chloride is a agent-linker conjugate for ADC with potent antitumor activity by using Duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128904. | |
| MC-Val-Cit-PAB-Exatecan | MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-Val-Cit-PAB-DX8951. CAS No. 2504068-28-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145929. | |
| MC-Val-Cit-PAB-Indibulin | MC-Val-Cit-PAB-Indibulin is a agent-linker conjugate for ADC with potent antitumor activity by using Indibulin (an orally applicable inhibitor of tubulin assembly), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-95-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128908. | |
| MC-Val-Cit-PAB-Ispinesib | MC-Val-Cit-PAB-Ispinesib (Compound 509) is a drug-linker conjugate for ADC, consisting of a cleavable ADC linker and Eg5 inhibitor. MC-Val-Cit-PAB-Ispinesib can be used for the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629737-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160441. | |
| MC-Val-Cit-PAB-MMAE | MC-Val-Cit-PAB-MMAE is a potent tubulin inhibitor (MMAE), Val-Cit-PAB-MMAE is an antibody drug conjugate. Alternative Names: VcMMAE; Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E; Vedotin. Grades: 95%. CAS No. 646502-53-6. Molecular formula: C68H105N11O15. Mole weight: 1316.63. | |
| MC-Val-Cit-PAB-MMAF | MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB-MMAF shows antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Vc-MMAF. CAS No. 863971-17-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112786. | |
| MC-Val-Cit-PAB-MMAF | MC-Val-Cit-PAB-MMAF is a potent tubulin inhibitor (MMAF), Val-Cit-PAB-MMAF is an antibody drug conjugate. Alternative Names: MC-VC-PAB-MMAF. Grades: ≥98%. CAS No. 863971-17-9. Molecular formula: C68H103N11O16. Mole weight: 1330.6. | |
| MC-Val-Cit-PAB-vinblastine | MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055896-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128902. | |
| MC-Val-D-Cit-PAB-PNP | MC-Val-D-Cit-PAB-PNP is a cleavable peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). MC-Val-D-Cit-PAB-PNP contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to antitumor compounds. Uses: Scientific research. Category: Signaling pathways. CAS No. 1350456-66-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-147021. | |
| MC-VA-PABC-MMAE | MC-VA-PABC-MMAE is a agent-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1818864-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147239. | |
| MC-VA-PAB-Exatecan | MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2680543-57-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147270. | |
| MC-VC-PAB-Azide | MC-VC-PAB-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Grades: 98.0%. Molecular formula: C33H48N10O9. Mole weight: 728.80. | |
| MC-vc-PAB-C6-a-amanitin | MC-vc-PAB-C6-a-amanitin is a drug-linker conjugate for ADC by using a-amanitin (a potent bicyclic octapeptide cytotoxin), linked via MC-vc-PAB-C6. Molecular formula: C74H105N17O22S. Mole weight: 1616.81. | |
| MC-VC-PABC-amide-PEG1-CH2-CC-885 | MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722697-82-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145448. | |
| MC-VC-PABC-Aur0101 | MC-VC-PABC-Aur0101 is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC. Uses: Scientific research. Category: Signaling pathways. CAS No. 1438849-92-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128955. | |
| MC-VC-PABC-MMAE | MC-VC-PABC-MMAE is a potent and selective antibody-drug conjugate (ADC) used in the treatment of various cancers, including breast cancer, ovarian cancer, and non-small cell lung cancer. It combines the efficacy of a monoclonal antibody with the cytotoxicity of a potent chemotherapeutic agent, delivering targeted therapy directly to cancer cells while minimizing systemic side effects. MC-VC-PABC-MMAE specifically targets cancer cells overexpressing certain antigens, making it a promising option for personalized cancer treatment. Alternative Names: MC-Val-Cit-PABC-MMAE; N-[[[4-[[N-[6-(2,5-Dioxo-1-pyrrolidinyl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide. CAS No. 1703779-06-9. Molecular formula: C68H107N11O15. Mole weight: 1318.64. | |
| MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA | MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA is a drug-linker conjugate for ADC by using Duocarmycin SA (a potent antitumor antibiotic), linked via MC-vc-PAB-DMEA-(PEG2). Molecular formula: C62H78ClN11O18. Mole weight: 1300.82. | |
| MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1616727-21-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136132A. | |
| MC-VC-PAB-NH2 TFA | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[[(2-aminoethyl)amino]carbonyl]oxy]methyl]phenyl]-, 2,2,2-trifluoroacetate (1:1). CAS No. 1616727-21-9. Molecular formula: C33H47F3N8O10. Mole weight: 772.77. | |
| MC-VC-PAB-O-Gemcitabine | MC-VC-PAB-O-Gemcitabine is a linker-antibiotic intermediate, which is part of the antibody-antibiotic conjugate (AAC) molecule. MC-VC-PAB-O-Gemcitabine is conjugated with the linker and the antibiotic Gemcitabine (HY-17026). MC-VC-PAB-O-Gemcitabine can be used to study the immunotherapy of bacterial infections and the development of new antibacterial drugs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639430-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171414. | |
| MC-vc-PAB-(PEG2)-duocarmycin DM | MC-vc-PAB-(PEG2)-duocarmycin DM is a drug-linker conjugate for ADC by using Duocarmycin DM (a potent antitumor antibiotic), linked via MA-MC-vc-PAB-(PEG2). Molecular formula: C63H80ClN11O14. Mole weight: 1250.85. | |
| MC-vc-PAB-(PEG2)-duocarmycin TM | MC-vc-PAB-(PEG2)-duocarmycin TM is a drug-linker conjugate for ADC by using Duocarmycin TM (a potent antitumor antibiotic), linked via MA-MC-vc-PAB-(PEG2). Molecular formula: C62H77ClN10O16. Mole weight: 1253.80. | |
| Mc-VC-PAB-SN38 | Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801838-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131057. | |
| Mc-VC-PAB-SN38 | Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl [(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl] carbonate. Grades: >98.0%. CAS No. 1801838-28-7. Molecular formula: C51H58N8O13. Mole weight: 991.05. | |
| MC-VC-PAB-Tubulysin M | MC-vc-PAB-Tubulysin M is a Drug-Linker Conjugates for ADC, consisting of a microtubule polymerization inhibitor Tubulysin M (an ADC cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639939-56-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136313. | |
| m-Cyanobenzyl chloride | m-Cyanobenzyl chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 64407-07-4. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| m-Cymene | m-Cymene (CAS# 535-77-3) is a miscellaneous reagent used in organic synthesis for oxygenation of alkylbenzenes with methylacridinium ion via photoinduced electron transfer. Alternative Names: 1-methyl-3-propan-2-ylbenzene. Grades: > 99.0 % (GC). CAS No. 535-77-3. Molecular formula: C10H14. Mole weight: 134.22. | |
| MD-222 | MD-222 is the first-in-class highly potent PROTAC degrader of MDM2. MD-222 consists of ligands for Cereblon and MDM2. MD-222 induces rapid degradation of the MDM2 protein and activation of wild-type p53 in cells. MD-222 has anticancer effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2136246-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-134823. | |
| MD-224 | MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 consists of ligands for Cereblon and MDM2. MD-224 induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells, and achieves an IC50 value of 1.5 nM in inhibition of growth of RS4;11 cells. MD-224 has the potential to be a new class of anticancer agent[1]. MD-224 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2136247-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-114312. | |
| MD2-TLR4-IN-1 | MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex antagonist. MD2-TLR4-IN-1 inhibits Lipopolysaccharides (HY-D1056) (LPS)-induced expression of TNF-α and IL-6 in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. MD2-TLR4-IN-1 can be used for the study of acute lung injury (ALI)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2249801-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128598. | |
| MDA-MB Transfection Reagent | Transfection Reagent for MDA-MB Breast Adenocarcinoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1794. |  Nevada, Texas, USA |
| MDBN, p97 Inhibitor (3,4-Methylenedioxy-b-nitrostyrene) | Cell-permeable. An irreversible inhibitor of p97 (IC50 <10uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1485-00-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| mDCBPy | mDCBPy. CAS No. 1867199-59-4. Molecular formula: C36H23N3O. Mole weight: 513.6g/mol. IUPAC Name: [3,5-di(carbazol-9-yl)phenyl]-pyridin-4-ylmethanone. SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC(=CC(=C4)C(=O)C5=CC=NC=C5)N6C7=CC=CC=C7C8=CC=CC=C86. InChI: InChI=1S/C36H23N3O/c40-36(24-17-19-37-20-18-24)25-21-26(38-32-13-5-1-9-28(32)29-10-2-6-14-33(29)38)23-27(22-25)39-34-15-7-3-11-30(34)31-12-4-8-16-35(31)39/h1-23H. |  |
| MDCK Transfection Reagent | Transfection Reagent for MDCK Kidney Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6846. | Nevada, Texas, USA |
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