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| Product | Description | |
|---|---|---|
| MC-Ala-Ala-PAB | MC-Ala-Ala-PAB is a cleavable ADC linker. Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1949793-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148464. |  |
| MCA-Lys-Leu-Lys(Dnp) | MCA-Lys-Leu-Lys(Dnp). Alternative Names: N6-(2,4-dinitrophenyl)-N2-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)-L-lysyl-L-leucyl-L-lysine. Molecular formula: C36H47N7O12. Mole weight: 769.81. |  |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-KPLGL-Dpa-AR-NH2 is an N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH2 with a Lys yields a fluorogenic peptide with improved substrate properties. Compared with Mca-PLGL-Dpa-AR-NH2, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH2 for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased by 2-9 times and 3 times, respectively, while those for gelatinases and matrilysin remain equally high. Alternative Names: L-Argininamide, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-L-argininamide; MMPs substrate Fluorogenic. Grades: ≥95%. CAS No. 720710-69-0. Molecular formula: C55H80N16O16. Mole weight: 1221.32. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 trifluoroacetate. CAS No. 1392300-20-7. | |
| Mca-PL | Mca-PL is a fluorogenic peptide that can be used in the synthesis of Mca-PLGL-Dpa-AR-NH2, a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. Alternative Names: Matrix Metalloproteinase-2 / Matrix Metalloproteinase-7 Fluorogenic Substrate Control; Mca-Pro-Leu-OH; MMP-2/MMP-7 Fluorogenic Substrate Control; N-[1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl]-L-leucine. Grades: ≥95%. CAS No. 140430-55-3. Molecular formula: C23H28N2O7. Mole weight: 444.48. | |
| Mca-PLAQAV-Dpa-RSSSR-NH2 | Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent substrate peptide that can be used to detect ADAM9, ADAM10, and tumor necrosis factor-α converting enzyme (TACE/ADAM17). Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescence resonance energy transfer-based substrate, and its activity can be determined by changes in fluorescence intensity upon cleavage (Ex = 320 nm; Em = 405 nm)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 192723-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3722. | |
| Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 TFA salt | Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 TFA salt. | |
| Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85·105 M-1s-1. It is a poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53·105 M-1s-1) and MMP-9 (kcat/Km = 0.33·105 M-1s-1). Alternative Names: L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-; 1-[(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-L-alaninamide. Grades: 95%. CAS No. 891198-38-2. Molecular formula: C53H70N12O20. Mole weight: 1195.19. | |
| Mca-Pro-Leu-OH | Mca-Pro-Leu is a fluorescently labeled dipeptide[1]. Uses: Scientific research. Category: Peptides. Alternative Names: Mca-Pro-Leu. CAS No. 140430-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4645. | |
| m-Carborane | m-Carborane. Group: Biochemicals. Alternative Names: 1, 7-Dicarbadodecaborane (12). Grades: Highly Purified. CAS No. 16986-24-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C2H12B10. US Biological Life Sciences. |  Worldwide |
| m-Carborane | m-Carborane. Alternative Names: 1,7-DICARBADODECARBORANE(12);M-CARBORANE;1,7-Dicarba-closo-dodecaboran;1,7-Dicarba-closo-dodecaborane(12);1,7-Dicarbadodecaboran;1,7-Dicarbadodecaboran(12);1,7-Dicarbadodecaborane;1,7-dicarbadodecaborane(12). CAS No. 16986-24-6. Molecular formula: C2H2B10. Mole weight: 134.2g/mol. Purity: N/A. SMILES: [B]1[B][B][B][B]C2[B]C([B]2)[B][B][B]1. InChI: InChI=1S/C2H2B10/c3-1-4-2(3)6-8-10-12-11-9-7-5-1/h1-2H. |  |
| m-Carborane-1-carboxylic Acid | m-Carborane-1-carboxylic Acid is used as a reactant or reagent in the synthetic preparation of ortho-carbaborane indomethacin pharmacophores as selective COX-2 enzyme inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 18581-81-2. Pack Sizes: 15mg, 30mg. Molecular Formula: C3H12B10O2, Molecular Weight: 188.24. US Biological Life Sciences. | Worldwide |
| m-Carboxybenzaldehyde | White powder, keep cold, 98%. Synonym: 3-Formylbenzoic Acid. CAS No. 619-21-6. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 150.13. MP/BP: M.P. 173-175. Order No: FR-2055. |  Frinton Laboratories |
| Mca-SEVNLDAEFK(Dnp)-NH2 | Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802078-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4920. | |
| MCA-SEVNLDAEFR-K(Dnp)-RR, amide | It is a FRET-based substrate. Alternative Names: Mca-(Asn670, Leu671)-APP770(667-676)-Lys(Dnp)-Arg-Arg amide; MCA-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2; Mca-(Asn670, Leu671)-Amyloid beta/A4 Protein Precursor770(667-676)-Lys(Dnp)-Arg-Arg amide. Grades: ≥95%. CAS No. 438625-61-7. Molecular formula: C86H125N27O29. Mole weight: 2001.08. | |
| Mca-YVADAP-Lys(Dnp)-OH | Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). It is cleaved by caspase-1 or ACE2 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify enzyme activity. Alternative Names: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH; Caspase-1 Fluorogenic Substrate V; N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine; L-Lysine, N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-. Grades: ≥95%. CAS No. 189696-01-3. Molecular formula: C53H64N10O19. Mole weight: 1145.15. | |
| MCB-36 | MCB-36 is a VHL-recruiting pan-KRAS PROTAC degrader without affecting KRAS transcription. MCB-36 exhibits minimal effects on HRAS and NRAS protein levels. MCB-36 binds to the GDP-loaded state of G12D, G12C, G12V, and wild-type KRAS with high affinities Kd ? 1 pM). MCB-36 decreases p-ERK levels, leading to cell apoptosis. MCB-36 effectively suppress KRASG12C inhibitor-resistant cancer cells and remodel the tumor immune microenvironment. MCB-36 can be used for the study of colorectal cancer and lung cancer (Pink: Target protein ligand; Blue: E3 ligand (HY-112078); Black: Linker (HY-W091879))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104382-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176786. | |
| MCB-613 | MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator (SMS), super-stimulates SRCs transcriptional activity.MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS).MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1162656-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19625. | |
| MCB-613 | MCB-613 is a potent steroid receptor coactivator (SRC) stimulator. Alternative Names: MCB 613; MCB613. Grades: 98%. CAS No. 1162656-22-5. Molecular formula: C20H20N2O. Mole weight: 304.39. | |
| MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 | MC-(β-Ala)-PABC-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 (Compound Ie) is a neodegrader conjugate, can be used in the synthesis of antibody neoDegrader conjugate (AnDC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722697-86-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-160497. | |
| MC-betaglucuronide-MMAE-1 | MC-betaglucuronide-MMAE-1 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide. Uses: Scientific research. Category: Signaling pathways. CAS No. 1703778-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136317. | |
| m-CBP | Phosphorescent host material and TADF emitter in OLEDs. Alternative Names: 3,3'-Di(9H-carbazol-9-yl)-1,1'-biphenyl. CAS No. 342638-54-4. Molecular formula: C36H24N2. Mole weight: 484.59. IUPAC Name: 9-[3-(3-carbazol-9-ylphenyl)phenyl]carbazole. SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC=CC(=C4)C5=CC(=CC=C5)N6C7=CC=CC=C7C8=CC=CC=C86. InChI: InChI=1S/C36H24N2/c1-5-19-33-29(15-1)30-16-2-6-20-34(30)37(33)27-13-9-11-25(23-27)26-12-10-14-28(24-26)38-35-21-7-3-17-31(35)32-18-4-8-22-36(32)38/h1-24H. | |
| MCC-555 | MCC-555, a thiazolidinedion derivative, has been found to be a PPAR agonist that was once studied as hyperglycaemic and hyperlipidaemic. The Phase II trial against Type-2 diabetes mellitus has been already discontinued. Alternative Names: Netoglitazone; MCC-555; MCC 555; MCC555; RWJ-241947; RWJ 241947; RWJ241947; isaglitazone; Netoglitazone; UNII-QOV2JZ647A; 5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 161600-01-7. Molecular formula: C21H16FNO3S. Mole weight: 381.42. | |
| MCC950 | MCC950 Inhibitor. Uses: Scientific use. Product Category: T6887. CAS No. 256373-96-3. |  |
| MCC950 | MCC950, also called as CP-456773 or CRID3, is a small molecule that selectively inhibits activation of NLRP3 but does not inhibit NLRC4, AIM2, TLR2 signaling, or priming of NLRP3. MCC950 can be used to treat inflammatory diseases. Alternative Names: MCC-950; MCC 950; CP-456773. CAS No. 210826-40-7. Molecular formula: C20H24N2O5S. Mole weight: 404.48. | |
| MCC950 | MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12815. | |
| MCC950 | MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. Group: Inhibitors. Alternative Names: CP-456773, CRID3. CAS No. 210826-40-7. Pack Sizes: 5mg. Product ID: S8930. Formula: C20H24N2O5S. Smiles: CC(C)(C1=COC(=C1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4)O. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| MCC950 sodium | MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12815A. | |
| MCC950 Sodium | MCC950 Sodium is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes. Group: Inhibitors. Alternative Names: CP-456773 Sodium, CRID3 Sodium. CAS No. 256373-96-3. Pack Sizes: 10mg. Product ID: S7809. Formula: C20H23N2O5S.Na. Smiles: CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+]. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| MCC-AAQ-Exa | MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3052836-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174279. | |
| MCdef | MCdef is a defensin-like peptide detected in hemocytes of Manila clams (Ruditapes philippinarum). MCdef showed highest activity against Streptococcus iniae and Staphylococcus aureus. | |
| Mc-Dexamethasone | Mc-Dexamethasone is a drug-linker conjugate for ADC. Mc-Dexamethasone is made toxin Dexamethasoneconjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist. Category: Active pharmaceutical ingredients. CAS No. 1618096-56-2. Product ID: API1618096562. Molecular formula: C29H38FN3O6. Mole weight: 543.636. |  |
| MC-DM1 | MC-DM1 is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker MC to make antibody agent conjugate (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1375089-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136286. | |
| MCD Peptide | 22-amino acid peptide with a strongly basic character and 2 disulfide bridges, , from Apis mellifera bee venom, a blocker of voltage-sensitive K+ channels with potent convulsant activity. Alternative Names: Peptide 401; Mast Cell Degranulating (MCD) Peptide; Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bridge: Cys3-Cys15, Cys5-Cys19); L-isoleucyl-L-lysyl-L-cysteinyl-L-asparagyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinyl-glycyl-L-lysyl-L-asparaginamide (3->15),(5->19)-bis(disulfide). Grades: ≥95%. CAS No. 32908-73-9. Molecular formula: C110H192N40O24S4. Mole weight: 2587.22. | |
| Mc-d-Val-d-Cit-PAB-PNP | Mc-d-Val-d-Cit-PAB-PNP is a cleavable ADC linker that can be used for synthesizing antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1350456-68-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173161. | |
| MC-EVCit-PAB-MMAE | MC-EVCit-PAB-MMAE (Linker-Payload 11) is a drug-linker conjugates for ADC. MC-EVCit-PAB-MMAE contains the ADCs linker (MC-EVCit-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873452-49-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-154915. | |
| MCF-7 Transfection Reagent | Transfection Reagent for MCF7 Breast Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1766. |  Nevada, Texas, USA |
| MC-GGFG-AM-(10Me-11F-Camptothecin) | MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873460-70-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153360. | |
| MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 | MC-GGFG-AM-(10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM-(10Me-11F-Camptothecin) (HY-153360). Modifying groups can be added group. MC-GGFG-AM-(10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-(2-Amino-4-fluoro-5-methylphenyl)-2-chloroethanone. CAS No. 1241391-14-9. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-400770. | |
| MC-GGFG-Exatecan | MC-GGFG-Exatecan (MC-GGFG-DX8951) is a agent-linker conjugate for ADC. MC-GGFG-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-Exatecan shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MC-GGFG-DX8951. CAS No. 1600418-29-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114233. | |
| MC-GGFG-PAB-Exatecan | MC-GGFG-PAB-Exatecan (Compound 94) is a drug-linker conjugate for ADC, and can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2928560-25-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160967. | |
| MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH | MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: (R)-10-Benzyl-23-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-6,9,12,15,18-pentaoxo-3-oxa-5,8,11,14,17-pentaazatricosanoic acid. CAS No. 1802520-40-6. Molecular formula: C28H36N6O10. Mole weight: 616.62. | |
| MC-Gly-Gly-Gly-PAB-MMAE | MC-Gly-Gly-Gly-PAB-MMAE has a cleavable ADC linker (MC-Gly-Gly-Gly-PAB) and a potent tubulin inhibitor (MMAE). Grades: ≥95%. Molecular formula: C63H94N10O15. Mole weight: 1231.50. | |
| MC-Gly-Gly-Phe | MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC). Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-15-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-44235. | |
| MC-Gly-Gly-Phe-Gly | MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mc-GGFG-OH. CAS No. 2413428-36-9. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-44246. | |
| MC-Gly-Gly-Phe-Gly | MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs). Alternative Names: (S)-5-Benzyl-18-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecan-1-oic acid. Grades: >98.0%. CAS No. 2413428-36-9. Molecular formula: C25H31N5O8. Mole weight: 529.54. | |
| MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Alternative Names: Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-. Grades: >98.0%. CAS No. 1599440-25-1. Molecular formula: C28H36N6O10. Mole weight: 616.62. | |
| MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599440-25-1. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-131990. | |
| MC-Gly-Gly-Phe-Gly-PAB-MMAE | MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055607-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132134. | |
| MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan | MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHR-A1811 Drug-linker. CAS No. 2414254-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148668. | |
| MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan | MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414254-52-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148668A. | |
| MCH (human, mouse, rat) | MCH is an endogenous melanin-concentration hormone receptor agonist with IC50 values of 0.3 and 1.5 nM at MCH1 and MCH2 receptors respectively. It can increase food intake in vivo. Alternative Names: Melanin concentrating hormone, human, mouse, rat; Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Gln-Val. Grades: ≥95% by HPLC. CAS No. 128315-56-0. Molecular formula: C105H160N30O26S4. Mole weight: 2386.84. | |
| m-Chloro Hippuric Acid | m-Chloro Hippuric Acid. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid; N-(3-Chlorobenzoyl)glycine; NSC 201882; m-Chlorohippuric Acid; N-(3-Chlorobenzoyl)glycine. Grades: Highly Purified. CAS No. 57728-59-3. Pack Sizes: 1g. Molecular Formula: C9H8ClNO3, Molecular Weight: 218.62. US Biological Life Sciences. | Worldwide |
| m-Chloro Hippuric Acid-d2,15N | m-Chloro Hippuric Acid-d2,15N. Group: Biochemicals. Alternative Names: (3-Chlorobenzoylamino) acetic Acid-d2,15N; N-(3-Chlorobenzoyl)glycine-d2,15N; NSC 201882-d2,15N; m-Chlorohippuric Acid-d2,15N; N-(3-Chlorobenzoyl)glycine-d2,15N. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C9H6D2Cl15NO3, Molecular Weight: 216.62. US Biological Life Sciences. | Worldwide |
| m-Chlorophenylbiguanide hydrochloride | m-Chlorophenylbiguanide hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2113-5-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| MCI-INI-3 | MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3 (with a Ki value of 0.55 μM for ALDH1A3 and a Ki value of 78.2 μM for ALDH1A1). MCIINI-3 inhibits the biosynthesis of retinoic acid and reduces the viability of GSC-83 and GSC-326 glioblastoma cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1011366-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-169884. | |
| MCL 0020 | MCL 0020. Group: Biochemicals. Grades: Purified. CAS No. 475498-26-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MCL 0020 | MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Alternative Names: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grades: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73. | |
| MCL-1/BCL-2-IN-1 | MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 4.45 and 3.18 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493256-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129681. | |
| Mcl-1 inhibitor 6 | Mcl-1 inhibitor 6 is an orally active, selective myeloid cell leukemia 1 (Mcl-1) protein inhibitor with a Kd of 0.23 nM and a Ki of 0.02 μM. Mcl-1 inhibitor 6 possesses superior selectivity over other Bcl-2 family members (Bcl-2, Bcl2A1, Bcl-xL, and Bcl-w, Kd>10 μM). Mcl-1 inhibitor 6 is a potent antitumor agent[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2598978-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132307. | |
| MCM-22 | MCM-22. CAS No. 12173-28-3. | |
| MCM-41 | MCM-41. | |
| MCM-41 | MCM-41. CAS No. 12173-28-3. | |
| Mc-MMAE | Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Alternative Names: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. Grades: ≥98%. CAS No. 863971-24-8. Molecular formula: C49H78N6O10. Mole weight: 911.18. | |
| Mc-MMAE | Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl-monomethylauristatin E. CAS No. 863971-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15741. | |
| McMMAF | McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimidocaproyl monomethylauristatin F. CAS No. 863971-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15578. | |
| Mc-MMAF | Mc-MMAF is a protective group-conjugated MMAF, MMAF is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin and it has lower cytotoxic activity than MMAE. Uses: Sgd 1269 is a potent tubulin inhibitor and is a toxin payload in antibody drug conjugate. it is a useful agent for make antibody drug conjugate (adc) for targeted drug delivery. Alternative Names: SGD-1269; SGD 1269; SGD1269; mc-MMAF; mcMMAF; L4-MMAF; Maleimidocaproyl-MMAF; Maleimidocaproyl monomethylauristatin F; Mafodotin.((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-methylhexanamido)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grades: ≥98%. CAS No. 863971-19-1. Molecular formula: C49H76N6O11. Mole weight: 925.18. | |
| McN3716 | McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methyl palmoxirate; NSC359682. CAS No. 69207-52-9. Pack Sizes: 1 mg. Product ID: HY-U00159. | |
| McN-A 343 | McN-A 343. Group: Biochemicals. Grades: Purified. CAS No. 55-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MCOPPB | MCOPPB is a drug which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07 and much weaker activity at other opioid receptors. MCOPPB exhibited potent anxiolytic effects in mouse models, and inhibited signaling through nociceptin receptor in the mouse brain. Alternative Names: 1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole. Grades: >98%. CAS No. 1028969-49-4. Molecular formula: C26H40N4. Mole weight: 408.634. | |
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