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Mevalonolactone-[1-13C] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-1-13C lactone; (+/-)-Mevalonolactone-1-13C. Grade: 98% by CP; 99% atom 13C. CAS No. 73834-54-5. Molecular formula: C5[13C]H10O3. Mole weight: 131.13.
Mevalonolactone-[1,2-13C2]
Mevalonolactone-[1,2-13C2] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-1,2-13C2 lactone. Grade: 98% by CP; 99% atom 13C. CAS No. 287111-36-8. Molecular formula: C4[13C]2H10O3. Mole weight: 132.13.
Mevalonolactone-[2-13C]
Mevalonolactone-[2-13C] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-2-13C lactone. Grade: 98% by CP; 99% atom 13C. CAS No. 53771-22-5. Molecular formula: C5[13C]H10O3. Mole weight: 131.13.
Mevalonolactone-[d3]
Mevalonolactone-(methyl-[d3]) is the isotope form of D,L-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Uses: A labelled metabolite from endophytes of the medicinal plant erythrina crista-galli. Synonyms: D,L-Mevalonic Acid Lactone D3; Tetrahydro-4-hydroxy-4-(methyl-d3)-2H-pyran-2-one; D,L-β-Hydroxy-β-(methyl-d3)-?-valerolactone; DL-Mevalonolactone-d3; Mevalonic Lactone-d3; Mevalonolactone-d3; NSC 90804-d3; Mevalonolactone-(methyl-d3). Grade: ≥97% by CP; 99% atom D. CAS No. 61219-76-9. Molecular formula: C6H7D3O3. Mole weight: 133.16.
Mevastatin
Mevastatin. Group: Biochemicals. Grades: Purified. CAS No. 73573-88-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Mevastatin
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Compactin; ML236B. CAS No. 73573-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg. Product ID: HY-17408.
Mevastatin
It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B. Grade: >98%. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51.
Mevastatin (Compactin)
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H34O5. CAS No. 73573-88-3. Prepack ID 58483586-5g. Molecular Weight 390.51. See USA prepack pricing.
Mevastatin (Compactin, Antibiotic ML 236B, ML 236B, SIPI 8915, Antibiotic SIpI 8915)
A fungal metabolite which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: Compactin, 6-Demethylvevinolin, CS-500, ML-236 B. Grades: Highly Purified. CAS No. 73573-88-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mevastatin Hydroxy Acid Sodium Salt
An active carboxylate of Mevastatin. It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt;[1S-[1α( βS*, δS*), 2α, 8 β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt; ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Monosodium Salt; ML 236B Sodium Salt. Grades: Highly Purified. CAS No. 99782-89-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Mevastatin Hydroxy Acid t-Butylamine Salt
A HMG-CoA reductase inhibitor. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoate 2-Methyl-2-propanamine. Grades: Highly Purified. CAS No. 262285-80-3. Pack Sizes: 50mg. US Biological Life Sciences.
Mevociclib (SY-1365) is a potent and first-in-class selective CDK7 inhibitor, with a Ki of 17.4 nM. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SY-1365. CAS No. 1816989-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128587.
Mexenone
Mexenone. CAS No. 1641-17-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Mexiletine
Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KOE-1173. CAS No. 31828-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g. Product ID: HY-119521.
Mexiletine-[d6] Hydrochloride
Mexiletine-[d6] Hydrochloride is the labelled analogue of Mexiletine. Mexiletine is a non-selective voltage-gated sodium channel blocker used for the treatment of arrhythmias. Synonyms: Mexiletine-D6 Hydrochloride; 1-(2,6-Dimethylphenoxy)-2-propanamine-d6 Hydrochloride; 1-Methyl-2-(2,6-xylyloxy)ethylamine-d6 Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1329835-60-0. Molecular formula: C11H12D6ClNO. Mole weight: 221.75.
Mexiletine Dimer
Mexiletine Dimer is an impurity compound of Mexiletine (M340800), an antiarrhythmic (class IB). Group: Biochemicals. Grades: Highly Purified. CAS No. 2059988-38-2. Pack Sizes: 25mg, 100mg. Molecular Formula: C22H32N2O2, Molecular Weight: 356.5. US Biological Life Sciences.
Worldwide
Mexiletine EP Impurity B
Mexiletine EP Impurity B. Uses: For analytical and research use. CAS No. 53012-41-2. Molecular formula: C11H14O2. Mole weight: 178.23. Catalog: APB53012412.
Mexiletine EP Impurity C
Mexiletine EP Impurity C. Uses: For analytical and research use. CAS No. 2059988-38-2. Molecular formula: C22H32N2O2. Mole weight: 356.51. Catalog: APB2059988382.
Mexiletine EP Impurity C (2HCl)
Mexiletine EP Impurity C (2HCl). Uses: For analytical and research use. CAS No. 2059988-39-3. Molecular formula: C22H34Cl2N2O2. Mole weight: 429.43. Catalog: APB2059988393.
Mexiletine EP Impurity D
Mexiletine EP Impurity D. Uses: For analytical and research use. CAS No. 26583-71-1. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB26583711.
Mexiletine hydrochloride
Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KOE-1173 hydrochloride. CAS No. 5370-1-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-A0093.
Mexiletine Hydrochloride
Antiarrhythmic (class IB). Group: Biochemicals. Alternative Names: 1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride; 1-Methyl-2-(2,6-xylyloxy)ethylamine Hydrochloride; Katen; Ko 1173; Ko 1173Cl; Mexilitene; Mexitil; Ritalmex. Grades: Highly Purified. CAS No. 5370-1-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Mexiletine Impurity 1
Mexiletine Impurity 1. Uses: For analytical and research use. CAS No. 55304-17-1. Molecular formula: C11H17NO2. Mole weight: 195.26. Catalog: APB55304171.
Mexiletine Impurity 10
Mexiletine Impurity 10. Uses: For analytical and research use. CAS No. 123363-66-6. Molecular formula: C11H18ClNO2. Mole weight: 231.72. Catalog: APB123363666.
Mexiletine Impurity 11
Mexiletine Impurity 11. Uses: For analytical and research use. CAS No. 61102-09-8. Molecular formula: C11H16O2. Mole weight: 180.25. Catalog: APB61102098.
Mexiletine Impurity 15
Mexiletine Impurity 15. Uses: For analytical and research use. CAS No. 61920-61-4. Molecular formula: C12H19NO. Mole weight: 193.29. Catalog: APB61920614.
Mexiletine Impurity 16
Mexiletine Impurity 16. Uses: For analytical and research use. CAS No. 149961-12-6. Molecular formula: C11H18ClNO2. Mole weight: 231.72. Catalog: APB149961126.
Mexiletine Impurity 17
Mexiletine Impurity 17. Uses: For analytical and research use. CAS No. 175660-80-7. Molecular formula: C11H17NO2. Mole weight: 195.26. Catalog: APB175660807.
Mexiletine Impurity 18
Mexiletine Impurity 18. Uses: For analytical and research use. CAS No. 26583-69-7. Molecular formula: C11H16O2. Mole weight: 180.25. Catalog: APB26583697.
Mexiletine Impurity 19
Mexiletine Impurity 19. Uses: For analytical and research use. CAS No. 68164-73-8. Molecular formula: C18H24O4S. Mole weight: 334.43. Catalog: APB68164738.
Mexiletine Impurity 2
Mexiletine Impurity 2. Uses: For analytical and research use. CAS No. 29238-40-2. Molecular formula: C11H18ClNO. Mole weight: 215.72. Catalog: APB29238402.
Mexiletine Impurity 20
Mexiletine Impurity 20. Uses: For analytical and research use. Molecular formula: C18H22O4S. Mole weight: 334.43. Catalog: APB08627.
Mexiletine Impurity 21
Mexiletine Impurity 21. Uses: For analytical and research use. CAS No. 1329835-60-0. Molecular formula: C11H12D6ClNO. Mole weight: 221.76. Catalog: APB1329835600.
Mexiletine Impurity 3
Mexiletine Impurity 3. Uses: For analytical and research use. CAS No. 55304-19-3. Molecular formula: C11H15NO2. Mole weight: 193.25. Catalog: APB55304193.
Mexiletine Impurity 4
Mexiletine Impurity 4. Uses: For analytical and research use. CAS No. 2415-09-0. Molecular formula: C8H10O2. Mole weight: 138.17. Catalog: APB2415090.
Mexiletine Impurity 5
Mexiletine Impurity 5. Uses: For analytical and research use. CAS No. 117322-90-4. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB117322904.
Mexiletine Impurity 6
Mexiletine Impurity 6. Uses: For analytical and research use. CAS No. 180966-61-4. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB180966614.
Mexiletine Impurity 7
Mexiletine Impurity 7. Uses: For analytical and research use. CAS No. 117322-92-6. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB117322926.
Mexobamol impurity 1
Mexobamol impurity 1. Uses: For analytical and research use. CAS No. 10488-39-8. Molecular formula: C11H15NO5. Mole weight: 241.24. Catalog: APB10488398.
Mexobamol impurity 2
Mexobamol impurity 2. Uses: For analytical and research use. CAS No. 2049-21-0. Molecular formula: C11H12O5. Mole weight: 224.21. Catalog: APB2049210.
Mexobamol impurity 3
Mexobamol impurity 3. Uses: For analytical and research use. CAS No. 1329610-40-3. Molecular formula: C11H15NO8S. Mole weight: 321.3. Catalog: APB1329610403.
Mexobamol impurity 4
Mexobamol impurity 4. Uses: For analytical and research use. Molecular formula: C13H18O6. Mole weight: 270.28. Catalog: APB11326.
Mezagitamab
Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-079. CAS No. 2227490-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99730.
Mezigdomide
Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-92480. CAS No. 2259648-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129395.
Mezlocillin
Mezlocillin. Group: Biochemicals. Grades: Highly Purified. CAS No. 51481-65-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Mezlocillin sodium
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H24N5NaO8S2. CAS No. 59798-30-0. Prepack ID 77075760-100mg. Molecular Weight 561.56. See USA prepack pricing.
Mezlocillin Sodium
Mezlocillin Sodium. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
MF-094
MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241025-68-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112438.
MF-438
MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an IC50 of 2.3 nM for rSCD1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 921605-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15822.
MF498
MF498 is a selective and orally active E prostanoid Receptor 4 (EP4) antagonist with a Ki value of 0.7 nM. MF498 can be used in the research of inflammation, such as rheumatoid and osteoarthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 915191-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10794.
MF63
MF63 is a selective and orally active inhibitor of mPGES-1. MF63 reduces the accumulation of PGE2, relieves pyresis, hyperalgesia, and inflammatory pain by inhibiting mPGES-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 892549-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13283.
MF-766
MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. MF-766 behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. MF-766 can be used for cancer and inflammation diseases research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1050656-06-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115487.
Mfa-hst5
Mfa-hst5 is from Macaca fascicularis and has antifungal, Candida spp. and Criptococcus spp. activities.
MF-DH-300
MF-DH-300 is a 15-PGDH inhibitor that can be applicable to the research of muscle disorders such as spinal muscular atrophy (SMA). Uses: Scientific research. Category: Signaling pathways. CAS No. 2673403-86-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176803.
MF-EA-705alpha
It is originally isolated from Streptomyces sp. MF-EA-705. And the MIC of MF-EA-705alpha against Candida albicans was 1 g/mL. Molecular formula: C20H22O2. Mole weight: 294.39.
MF-EA-705beta
MF-EA-705beta is an antifungal antibiotic isolated from Streptomyces sp. MF-EA-705. Synonyms: (3E,5E,7Z)-8-{2-[(1Z)-but-1-en-1-yl]-4-methylphenyl}nona-3,5,7-trienoic acid. Molecular formula: C20H24O2. Mole weight: 294.39.
Mfe I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑AATTG GTTAA↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mfe I from Mycoplasma fermentans. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1131RE.
MFH290
MFH290 is a potent and highly selective cyclin-dependent kinase 12/13 (CDK12/13) covalent inhibitor. MFH290 forms a covalent bond with Cys-1039 of CDK12 and exhibits excellent kinome selectivity and inhibits the phosphorylation of serine-2 in the C-terminal domain (CTD) of RNA-polymerase II (Pol II). MFH290 is used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2088715-91-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153244.
MFI8
MFI8 is a small molecule inhibitor of mitochondrial[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 694488-83-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150031.
m-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers)
Intermediate in the synthesis of m-Fluoro Prasugrel (F595870). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
MFN2 agonist-1
MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial clumping (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230047-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123985.
MF-PGDH-008
MF-PGDH-008 serves as an inhibitor of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 452077-89-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117723.
MFZ 10-7
MFZ 10-7. Group: Biochemicals. Grades: Purified. CAS No. 1224431-15-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MG 101
MG 101. Group: Biochemicals. Grades: Purified. CAS No. 110044-82-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MG-101
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Calpain inhibitor I; Ac-LLnL-CHO; ALLN. CAS No. 110044-82-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18964.
A potent, reversible proteasome inhibitor with Ki of 21nM for 20S proteasome and 35nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome. Also shown to induce apoptosis in Rat-1 and PC12 cells via a p3-independent pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MG132
MG132 ((S,R,S)-(-)-MG132, Z-Leu-D-Leu-Leu-al) is a potent proteasome (ChTL, TL, and PGPH) inhibitor. MG132 also inhibits calpain (IC50=1.2 μM). MG132 can be used to induce animal models of Parkinsons disease. Group: Inhibitors. Alternative Names: (S,R,S)-(-)-MG-132, Z-Leu-D-Leu-Leu-al. CAS No. 1211877-36-9. Pack Sizes: 5mg. Product ID: S2619. Formula: C26H41N3O5. Smiles: CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1. Storage Conditions: 2 years -80 in solvent.
United States; Europe
MG-132
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Z-Leu-Leu-Leu-al; MG132. CAS No. 133407-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13259.