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| Product | Description | |
|---|---|---|
| Misitatug | HY-P990929 is an MSLN-targeting IgG1κ type chimeric antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC-88 Antibody. CAS No. 2767203-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990929. |  |
| Misoprostol | A cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Alternative Names: (11α,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Cytotec; Misogon; Misoprostil; SC 29333. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Misoprostol, 1% in Cellulose | Misoprostol, 1% in Cellulose. Group: Biochemicals. Alternative Names: (11a,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester; Cytotec; Misogon. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C22H38O5, Molecular Weight: 382.53. US Biological Life Sciences. | Worldwide |
| Misoprostol acid | Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112137-89-0. Pack Sizes: 1 mg (27.14 mM * 100 μL in Methyl acetate). Product ID: HY-118189. | |
| Misoprostol acid (10 mg in 1 mL methyl acetate) | Misoprostol acid (10 mg in 1 mL methyl acetate). Group: Biochemicals. Alternative Names: (11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic acid; Misoprostol free acid; (+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1. Grades: Highly Purified. CAS No. 112137-89-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H36O5. US Biological Life Sciences. | Worldwide |
| Misoprostol-d4 | Labelled Misoprostol, a cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Misoprostol EP Impurity A | Misoprostol EP Impurity A. Uses: For analytical and research use. CAS No. 1788085-78-8. Molecular formula: C22H38O5. Mole weight: 382.54. Catalog: APB1788085788. |  |
| Misoprostol Impurity 1 | Misoprostol Impurity 1. Uses: For analytical and research use. Molecular formula: C22H38O5. Mole weight: 382.54. Catalog: APB12291. | |
| Misoprostol Impurity 2 | Misoprostol Impurity 2. Uses: For analytical and research use. CAS No. 58682-86-3. Molecular formula: C22H36O4. Mole weight: 364.53. Catalog: APB58682863. | |
| Mitapivat | Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-348. CAS No. 1260075-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-12689. | |
| Mitazalimab | Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADC-1013; JNJ-64457107; Vanalimab. CAS No. 2055640-86-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99742. | |
| Mithramycin | Mithramycin was the first of the aureolic acid class of antitumor antibiotics isolated from Streptomyces. Mithramycin inhibits transcription and protein synthesis by non-covalent binding with G-C-rich duplex DNA in the presence of magnesium and zinc ions. Mithramycin has also been shown to induce differentiation of leukemic cells accompanied by an early decrease in c-myc expression and selectively inhibit collagen-1 gene expression in human fibroblasts. Group: Biochemicals. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Mithramycin A | Mithramycin A. Group: Biochemicals. Alternative Names: Aureolic acid. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C52H76O24. US Biological Life Sciences. | Worldwide |
| Mithramycin A | Mithramycin A is an antineoplastic antibiotic produced by Streptomyces plicatus. Mithramycin A is a polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA. Uses: Antibiotics, antineoplastic, fluorescent dyes, nucleic acid synthesis inhibitors, protein synthesis inhibitors. Synonyms: D-threo-2-Pentulose, 5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-, (1S)-; [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose; A 2371; Antibiotic LA 7017; Aureolic acid; Mithracin; Mithramycin A; Mitramycin; NSC 24559; PA 144; Plicamycin; Plicatomycin. Grade: ≥95% by HPLC. CAS No. 18378-89-7. Molecular formula: C52H76O24. Mole weight: 1085.14. |  |
| Mithramycin A | 5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H76O24. CAS No. 18378-89-7. Prepack ID 50053396-5mg. Molecular Weight 1085.15. See USA prepack pricing. |  |
| Mitiglinide Acyl- β-D-glucuronide | Mitiglinide Acyl- β-D-glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H33NO9, Molecular Weight: 491.53. US Biological Life Sciences. | Worldwide |
| Mitiglinide calcium | Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Synonyms: KAD-1229; KAD 1229; KAD1229. Grade: >98%. CAS No. 145525-41-3. Molecular formula: (C19H24NO3)2.Ca. Mole weight: 668.88. | |
| Mitiglinide calcium | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H24NO3 ·0.5Ca. CAS No. 145525-41-3. Prepack ID 23856829-100mg. Molecular Weight 334.44. See USA prepack pricing. | |
| Mitiglinide Calcium | Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Category: Hypoglycemic apis. Synonyms: Mitiglinide calcium hydrate. Mitiglinide calcium dihydrate. Glufast. UNII-9651C21W3Z. CAS No. 207844-01-7. Product ID: API207844017. Molecular formula: C38H52CaN2O8. Mole weight: 704.9. EINECS: 691-325-2. SMILES: C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].O.O.[Ca+2]. Appearance: White or off-white crystalline powder. Standard: In-house. |  |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KAD-1229; S-21403. CAS No. 207844-01-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0682A. | |
| Mitiglinide impurity 1 | Mitiglinide impurity 1. Uses: For analytical and research use. Molecular formula: C19H25NO3. Mole weight: 315.41. Catalog: APB11817. | |
| Mitiglinide Impurity 2 | Mitiglinide Impurity 2. Uses: For analytical and research use. Alternative Names: (1R,2S)-cyclohexane-1,2-dicarboxylic acid. CAS No. 610-09-3. Molecular formula: C8H12O4. Mole weight: 172.18. Catalog: APB610093. | |
| Mitiperstat | Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat inhibits MPO and thyroid peroxidase (TPO) with IC50s of 1.5 nM and 0.69 μM. Mitiperstat exhibits a weak inhibitory activity against CYP3A4 with an IC50 of 6 μM. Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD4831. CAS No. 1933460-19-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145581. | |
| Mitiromycin A2 | Mitiromycin A2 is a quinone antibiotic produced by Streptorverticilliim verticillatus AA-849, AB-286. It has weak anti-Gram-positive bacteria activity. Synonyms: Mitiromycin; 2-Hydroxy-6-methoxy-7,11-dimethyl-4,4a,10,10a,11,11a-hexahydroazireno[2',3':3,4]pyrrolo[1,2-a][1,3]oxazino[4,5-b]indole-5,8-dione. CAS No. 27164-43-8. Molecular formula: C16H17N3O5. Mole weight: 331.32. | |
| MitMAB | MitMAB. Group: Biochemicals. Grades: Purified. CAS No. 1119-97-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MitoBADY | MitoBADY is a mitochondria-selective Raman probe that successfully visualizes mitochondria in live HeLa cells at a concentration of 200-400 nM for 10 minutes. MitoBADY can be utilized for the study of mitochondrial dynamics[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1644119-76-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-123583. | |
| MitoBloCK-1 | MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MB-1. CAS No. 373370-73-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122658. | |
| MitoBloCK-10 | MitoBloCK-10 (MB-10) is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity. MitoBloCK-10 (MB-10) inhibits Tim44 (C-terminal domain) binding to the precursor and to Hsp70[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 394694-98-5. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115467. | |
| MitoBloCK-6 | MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce Apoptosis via cytochrome c release. MitoBloCK-6 inhibits growth of developing zebrafish motor neurons. MitoBloCK-6 has anticancer activity against liver cancer and leukemia[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303215-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-122652. | |
| Mitochondrial fusion promoter M1 | Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 219315-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111475. | |
| mitochondrial intermediate peptidase | A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: mitochondrial intermediate precursor-processing proteinase; MIP. Enzyme Commission Number: EC 3.4.24.59. CAS No. 136447-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4341; mitochondrial intermediate peptidase; EC 3.4.24.59; 136447-30-8; mitochondrial intermediate precursor-processing proteinase; MIP. Cat No: EXWM-4341. |  |
| mitochondrial processing peptidase | Known from the mitochondrial matrix of fungi and mammals. Formed from two subunits, both homologous with pitrilysin, and the products of the MAS1 and MAS2 genes in yeast. In peptidase family M16 (pitrilysin family). Group: Enzymes. Synonyms: processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Enzyme Commission Number: EC 3.4.24.64. CAS No. 86280-61-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4347; mitochondrial processing peptidase; EC 3.4.24.64; 86280-61-7; processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Cat No: EXWM-4347. | |
| mitochondrial protein-transporting ATPase | A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved in the transport of proteins or preproteins into mitochondria using the TIM protein complex. (TIM is the protein transport machinery of the inner mitochondrial membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.). Group: Enzymes. Enzyme Commission Number: EC 7.4.2.3 (Formerly EC 3.6.3.51). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4690; mitochondrial protein-transporting ATPase; EC 3.6.3.51. Cat No: EXWM-4690. | |
| mitochondrial tRNA pseudouridine27/28 synthase | The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA. Group: Enzymes. Synonyms: Pus2; Pus2p; RNA:pseudouridine synthases 2. Enzyme Commission Number: EC 5.4.99.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5586; mitochondrial tRNA pseudouridine27/28 synthase; EC 5.4.99.44; Pus2; Pus2p; RNA:pseudouridine synthases 2. Cat No: EXWM-5586. | |
| Mitochondria-Targeted Compound Library | A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries. |  |
| Mitochonic acid 5 | Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MA-5. CAS No. 1354707-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111536. | |
| Mitochonic Acid 5 | Mitochonic Acid 5. Alternative Names: Mitochonic Acid 5; MA-5; MA 5; MA5. CAS No. 1354707-41-7. Purity: >98%. Product ID: ACM1354707417. Molecular formula: C18H13F2NO3. Mole weight: 329.30. IUPAC Name: 4-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| MitoEbselen-2 chloride | MitoEbselen-2 chloride (MitoPeroxidase 2), a mitochondria-targeted mimic of glutathione peroxidase, is a radiation mitigator. MitoEbselen-2 chloride is effective in reducing lipid hydroperoxides, preventing apoptotic cell death[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoPeroxidase 2. CAS No. 1638973-78-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-139381. | |
| Mitofusin 2 Antibody [J12N7] | MFN2,Mfn2 / Mitofusin 2,Mitofusin 2,Mitofusin-2. Group: Antibodies. Alternative Names: MFN2,Mitofusin-2. Pack Sizes: 20uL. Product ID: F0566. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| mitogen-activated protein kinase | Phosphorylation of specific tyrosineand threonine residues in the activation loop of this enzyme by EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) is necessary for enzyme activation. Once activated, the enzyme phosphorylates target substrates on serine or threonine residues followed by a proline. A distinguishing feature of all MAPKs is the conserved sequence Thr-Xaa-Tyr (TXY). Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth.pk; PMK-1; PMK-2; PMK-3; pp42; pp44mapk; p44mpk; SAPK; STK26; stress-activated protein kinase. Enzyme Commission Number: EC 2.7.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3144; mitogen-activated protein kinase; EC 2.7.11.24; c-Jun N-terminal kinase; Dp38; ERK; ERK1; ERK2; extracellular signal-regulated kinase; JNK; JNK3α1; LeMPK3; MAP kinase; MAP-2 kinase; MAPK; MBP kinase I; MBP kinase II; microtubule-associated protein 2 kinase; microtubule-associated protein kinase; myelin basic protein kinase; p38Δ; p38-2; p42 mitogen-activated protein kinase; p42mapk; PMK-1; PMK-. | |
| Mitogen activated protein kinase from rat, Recombinant | Mitogen-activated protein kinases (MAPK) are protein kinases that are specific to the amino acids serine, threonine, and tyrosine. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. > 95% (sds-page), buffered aqueous glycerol solution, recombinant, expressed in e. coli (n-terminal histidine tagged). Group: Enzymes. Synonyms: ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Purity: > 95% (SDS-PAGE). MAP kinase. Mole weight: mol wt 42 kDa. Activity: > 500 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Rat. ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Pack: vial of 100 ng. Cat No: NATE-0443. | |
| mitogen-activated protein kinase kinase | This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK. Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162. | |
| mitogen-activated protein kinase kinase kinase | This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.mes. Synonyms: cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Enzyme Commission Number: EC 2.7.11.25. CAS No. 146702-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3145; mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; 146702-84-3; cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Cat No: EXWM-3145. | |
| Mitogenic Pentapeptide | Mitogenic Pentapeptide represents a potent activator for monocytes/macrophages and B lymphocytes. Synonyms: Tripalmitoyl pentapeptide; Bppp-cssaa; P3C-Ssna; Pam3Cys-ser-ser-asn-ala; 2,3-Bis(palmitoyloxy)propyl-N-palmitoylpentapeptide. CAS No. 87173-03-3. Molecular formula: C67H124N6O14S. Mole weight: 1269.80. | |
| Mitoglitazone | Mitoglitazone. Uses: For analytical and research use. CAS No. 146062-49-9. Mole weight: 370.42. Catalog: AP146062499. | |
| Mitoguazone | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106634. | |
| Mito-LND | Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mito-Lonidamine. CAS No. 2361564-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134832. | |
| mitomycin 6-O-methyltransferase | The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. Group: Enzymes. Synonyms: MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Enzyme Commission Number: EC 2.1.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1924; mitomycin 6-O-methyltransferase; EC 2.1.1.316; MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Cat No: EXWM-1924. | |
| Mitomycin A | Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity B; Mitiromycin B. Grade: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin B | Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grade: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| Mitomycin C | Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Synonyms: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grade: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Mitomycin C | An antitumor antibiotic. It is used as antineoplastic. Group: Biochemicals. Alternative Names: [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; MMC; Ametycine; Mutamycin; Mitonco; Mitoplus. Grades: Highly Purified. CAS No. 50-07-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mitomycin C | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-25mg. Molecular Weight 334.33. See USA prepack pricing. | |
| Mitomycin C | Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner.This product is a hazardous chemical (acute toxicity / flammable / skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing. Group: Inhibitors. Alternative Names: Ametycine. CAS No. 50-07-7. Pack Sizes: 10mg. Product ID: S8146. Formula: C15H18N4O5. Smiles: CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Mitomycin C | 2mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-2mg. Molecular Weight 334.33. See USA prepack pricing. | |
| Mitomycin C-[13C,d3] | An isotope labelled Mitomycin C, which is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Synonyms: Mitomycin C-13C,d3; ((1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-(methyl-13C-d3)-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate. Grade: > 95%. Molecular formula: C14[13C]H15D3N4O5. Mole weight: 338.34. | |
| Mitomycin C Pure (NaCl-Free) | Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 4mg, 12mg, 24mg, 40mg. US Biological Life Sciences. | Worldwide |
| Mitomycin C w/NaCl | Supplied as a preparation of Mitomycin C with sodium chloride in a ratio of 2mg Mitomycin C and 48mg sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, 3: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| Mitomycin D | Mitomycin D is a mito-mycin antibiotic produced by Streptomyces caespitosus with anti-tumor activity. It is also a semi-synthetic antibiotic with anti-leukemic properties. Uses: An antitumor antibiotic. it is used as antineoplastic. Synonyms: 7-Demethoxy-7-aminomitomycin B; (1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [(1aS,8S,8aR,8bS)-6-Amino-8a-hydroxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methylcarbamate; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-, (1aS-(1a-α,8-β,8a-α,8b-α))-; BRN 4720574; NSC 123106. Grade: 95%. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33. | |
| Mitomycin D | Mitomycin D. Group: Biochemicals. Alternative Names: (1aS, 8R, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 10169-34-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H18N4O5. US Biological Life Sciences. | Worldwide |
| Mitomycin EP Impurity A | Mitomycin EP Impurity A. Uses: For analytical and research use. CAS No. 621-79-4. Molecular formula: C9H9NO. Mole weight: 147.17. Catalog: APB621794. | |
| Mitomycin EP Impurity B | Mitomycin EP Impurity B. Uses: For analytical and research use. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055394. | |
| Mitomycin EP Impurity C | Mitomycin EP Impurity C. Uses: For analytical and research use. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055407. | |
| Mitomycin EP Impurity D | Mitomycin EP Impurity D. Uses: For analytical and research use. CAS No. 111750-67-5. Molecular formula: C15H18N4O5. Mole weight: 334.33. Catalog: APB111750675. | |
| Mitonafide | A Naphthalimides with potent anticancer activity. Group: Biochemicals. Alternative Names: 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione. Grades: Highly Purified. CAS No. 54824-17-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Mitonafide | Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 300288. CAS No. 54824-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119182. | |
| MitoPerOx | MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1392820-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125623. | |
| MitoPQ | MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoParaquat. CAS No. 1821370-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130278. | |
| MitoQ (Mitoquinone) Mesylate | MitoQ (Mitoquinone) mesylate is a TPP-based, mitochondria-targeted antioxidant that blocks H2O2-induced intracellular ROS responses and protects against oxidative damage. This product is a waxy solid. Group: Inhibitors. Alternative Names: MitoQ10 mesylate, Mitoubiquinone mesylate. CAS No. 845959-50-4. Pack Sizes: 5mg. Product ID: S8978. Formula: C38H47O7PS. Smiles: CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.CS(=O)(=O)[O-]. Storage Conditions: 2 years -20°C liquid. | United States; Europe |
| Mitoquinol | Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845959-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124410. | |
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