A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Metyrosine is a selective tyrosine hydroxylase enzyme inhibitor. Metyrosine exerts anti-inflammatory and anti-ulcerative effects. Metyrosine significantly inhibits high COX-2 activity [1]. Metyrosine is a very effective agent for blood pressure control [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 672-87-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W015007.
Meucin-24
Meucin-24 was found in scorpion Mesobuthus eupeus. The synthetic meucin-24 inhibits the development of P. berghei ookinetes, kills intraerythrocytic P.falciparum, and is cytotoxic to the Drosophila S2 cell at micromolar concentrations.
Meucin-25
Meucin-25 was found in scorpion Mesobuthus eupeus. This synthetic cationic peptide inhibits the development of Plasmodium berghei ookinetes, kills intraerythrocytic P.falciparum, and is cytotoxic to the Drosophila S2 cell at micromolar concentrations. Synonyms: BeL-170; Non-disulfide-bridged peptide 5.2.
mevaldate reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD+ oxidoreductase. This enzyme is also called mevalonic dehydrogenase. Group: Enzymes. Synonyms: mevalonic dehydrogenase. Enzyme Commission Number: EC 1.1.1.32. CAS No. 9028-33-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0232; mevaldate reductase; EC 1.1.1.32; 9028-33-5; mevalonic dehydrogenase. Cat No: EXWM-0232.
mevaldate reductase (NADPH)
May be identical with EC 1.1.1.2 [alcohol dehydrogenase (NADP+)]. Group: Enzymes. Synonyms: mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase; mevaldate reductase (NADPH2). Enzyme Commission Number: EC 1.1.1.33. CAS No. 9028-34-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0243; mevaldate reductase (NADPH); EC 1.1.1.33; 9028-34-6; mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase; mevaldate reductase (NADPH2). Cat No: EXWM-0243.
Me-Val-OBn HCl
Me-Val-OBn HCl. Synonyms: Me Val OBn HCl. CAS No. 89536-89-0. Molecular formula: C13H20ClNO2. Mole weight: 257.75.
mevalonate 3-kinase
Mevalonate 3-kinase and mevalonate-3-phosphate-5-kinase (EC 2.7.1.186) act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum. Mevalonate 3-kinase is different from mevalonate kinase, EC 2.7.1.36, which transfers phosphate to position 5 of (R)-mevalonate and is part of the classical mevalonate pathway in eukaryotes and archaea. Group: Enzymes. Synonyms: ATP:(R)-MVA 3-phosphotransferase. Enzyme Commission Number: EC 2.7.1.185. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3017; mevalonate 3-kinase; EC 2.7.1.185; ATP:(R)-MVA 3-phosphotransferase. Cat No: EXWM-3017.
mevalonate-3-phosphate 5-kinase
Mevalonate 3-kinase (EC 2.7.1.185) and mevalonate-3-phosphate-5-kinase act sequentially in an alternate mevalonate pathway in the archaeon Thermoplasma acidophilum. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.186. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3018; mevalonate-3-phosphate 5-kinase; EC 2.7.1.186. Cat No: EXWM-3018.
mevalonate kinase
CTP, GTP and UTP can also act as donors. Group: Enzymes. Synonyms: mevalonate kinase (phosphorylating); mevalonate phosphokinase; mevalonic acid kinase; mevalonic kinase; mevalonate 5-phosphotransferase MVA kinase; ATP:mevalonate 5-phosphotransferase. Enzyme Commission Number: EC 2.7.1.36. CAS No. 9026-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3067; mevalonate kinase; EC 2.7.1.36; 9026-52-2; mevalonate kinase (phosphorylating); mevalonate phosphokinase; mevalonic acid kinase; mevalonic kinase; mevalonate 5-phosphotransferase MVA kinase; ATP:mevalonate 5-phosphotransferase. Cat No: EXWM-3067.
Mevalonic acid lithium salt
Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: MVA lithium salt. CAS No. 2618458-93-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-113071A.
Mevalonic Lactone Methacrylate, ≥98%,stabilized with MEHQ
Mevalonolactone-[1-13C] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-1-13C lactone; (+/-)-Mevalonolactone-1-13C. Grade: 98% by CP; 99% atom 13C. CAS No. 73834-54-5. Molecular formula: C5[13C]H10O3. Mole weight: 131.13.
Mevalonolactone-[1,2-13C2]
Mevalonolactone-[1,2-13C2] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-1,2-13C2 lactone. Grade: 98% by CP; 99% atom 13C. CAS No. 287111-36-8. Molecular formula: C4[13C]2H10O3. Mole weight: 132.13.
Mevalonolactone-[2-13C]
Mevalonolactone-[2-13C] is the isotope form of DL-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Synonyms: DL-Mevalonic-2-13C lactone. Grade: 98% by CP; 99% atom 13C. CAS No. 53771-22-5. Molecular formula: C5[13C]H10O3. Mole weight: 131.13.
Mevalonolactone-2-13C
99 atom % 13C, 98% (CP). Group: Fluorescence/luminescence spectroscopy.
Mevalonolactone-[d3]
Mevalonolactone-(methyl-[d3]) is the isotope form of D,L-Mevalonic Acid Lactone, which is a metabolite from endophytes of the medicinal plant Erythrina crista-galli. Uses: A labelled metabolite from endophytes of the medicinal plant erythrina crista-galli. Synonyms: D,L-Mevalonic Acid Lactone D3; Tetrahydro-4-hydroxy-4-(methyl-d3)-2H-pyran-2-one; D,L-β-Hydroxy-β-(methyl-d3)-?-valerolactone; DL-Mevalonolactone-d3; Mevalonic Lactone-d3; Mevalonolactone-d3; NSC 90804-d3; Mevalonolactone-(methyl-d3). Grade: ≥97% by CP; 99% atom D. CAS No. 61219-76-9. Molecular formula: C6H7D3O3. Mole weight: 133.16.
Mevastatin
It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B. Grade: >98%. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51.
Mevastatin
?98% (HPLC), powder or crystals. Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsimpurity standardspharmaceutical toxicology. Alternative Names: Antibiotic ML 236B, L 637312, ML 236B lactone, Lovastatin Imp. A (EP), (2S)-2-Methylbutanoic acid (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, Compactin, Compactin (Penicillium), (1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate, (+)-Compactin, ML 236B, Statin I, 2-Methylbutanoic acid [1S-[1alpha(R*),7beta,8beta(2S*,4S*),8abeta]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester,Mevastatin, CS 500 (antibiotic), NSC 281245, CS 500.
Mevastatin
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51. Purity: 0.98. IUPACName: [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate. Canonical SMILES: CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O. Product ID: ACM73573883. Alfa Chemistry ISO 9001:2015 Certified.
Mevastatin
Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis , arrests cancer cells in G 0 /G 1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Compactin; ML236B. CAS No. 73573-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17408.
Mevastatin
Mevastatin. Group: Biochemicals. Grades: Purified. CAS No. 73573-88-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Mevastatin (Compactin)
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H34O5. CAS No. 73573-88-3. Prepack ID 58483586-5g. Molecular Weight 390.51. See USA prepack pricing.
Mevastatin (Compactin, Antibiotic ML 236B, ML 236B, SIPI 8915, Antibiotic SIpI 8915)
A fungal metabolite which is a potent inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: Compactin, 6-Demethylvevinolin, CS-500, ML-236 B. Grades: Highly Purified. CAS No. 73573-88-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Mevastatin Hydroxy Acid Sodium Salt
An active carboxylate of Mevastatin. It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Sodium Salt;[1S-[1α( βS*, δS*), 2α, 8 β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt; ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid Monosodium Salt; ML 236B Sodium Salt. Grades: Highly Purified. CAS No. 99782-89-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Mevastatin Hydroxy Acid t-Butylamine Salt
A HMG-CoA reductase inhibitor. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 8S, 8aR)-1, 2, 6, 7, 8, 8a-Hexahydro- β,δ-dihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoate 2-Methyl-2-propanamine. Grades: Highly Purified. CAS No. 262285-80-3. Pack Sizes: 50mg. US Biological Life Sciences.
Mevociclib (SY-1365) is a potent and first-in-class selective CDK7 inhibitor, with a Ki of 17.4 nM. Mevociclib exhibits anti-proliferative and apoptotic effects in solid tumor cell lines. Mevociclib possesses anti-tumor activity in hematological and multiple aggressive solid tumors[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SY-1365. CAS No. 1816989-16-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128587.
Mexiletine-[d6] Hydrochloride
Mexiletine-[d6] Hydrochloride is the labelled analogue of Mexiletine. Mexiletine is a non-selective voltage-gated sodium channel blocker used for the treatment of arrhythmias. Synonyms: Mexiletine-D6 Hydrochloride; 1-(2,6-Dimethylphenoxy)-2-propanamine-d6 Hydrochloride; 1-Methyl-2-(2,6-xylyloxy)ethylamine-d6 Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1329835-60-0. Molecular formula: C11H12D6ClNO. Mole weight: 221.75.
Mexiletine Dimer
Mexiletine Dimer is an impurity compound of Mexiletine (M340800), an antiarrhythmic (class IB). Group: Biochemicals. Grades: Highly Purified. CAS No. 2059988-38-2. Pack Sizes: 25mg, 100mg. Molecular Formula: C22H32N2O2, Molecular Weight: 356.5. US Biological Life Sciences.
Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels ( IC 50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KOE-1173 hydrochloride. CAS No. 5370-1-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-A0093.
Mexiletine hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Mexiletine Hydrochloride
Antiarrhythmic (class IB). Group: Biochemicals. Alternative Names: 1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride; 1-Methyl-2-(2,6-xylyloxy)ethylamine Hydrochloride; Katen; Ko 1173; Ko 1173Cl; Mexilitene; Mexitil; Ritalmex. Grades: Highly Purified. CAS No. 5370-1-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Mexiletine Hydrochloride
Antiarrhythmic drug, inhibits Na+ inward flow and promotes K+ outward flow in cardiomyocytes, shortens the action potential duration of Purdue fibers and the effective period of inactivity, delays intraventricular conduction, and raises the threshold of ventricular fibrillation. It is used for ventricular arrhythmia caused by various reasons. Alternative Names: Mexiletine HCL. Mexitil. Katen. CAS No. 5370-1-4. Product ID: API5370014. Molecular formula: C11H18ClNO. Mole weight: 215.72. EINECS: 226-362-1. SMILES: CC1=C(C(=CC=C1)C)OCC(C)N.Cl. Standard: USP/BP/EP. Category: Antiarrhythmic APIs.
Mexiletine Impurity 10
Mexiletine Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123363-66-6. Molecular formula: C11H18ClNO2. Mole weight: 231.72. Catalog: APB123363666.
Mexiletine Impurity 21
Mexiletine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329835-60-0. Molecular formula: C11H12D6ClNO. Mole weight: 221.76. Catalog: APB1329835600.
Mexobamol impurity 1
Mexobamol impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10488-39-8. Molecular formula: C11H15NO5. Mole weight: 241.24. Catalog: APB10488398.
Mexobamol impurity 3
Mexobamol impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329610-40-3. Molecular formula: C11H15NO8S. Mole weight: 321.3. Catalog: APB1329610403.
Mezagitamab
Mezagitamab (TAK-079) is a IgG1λ anti- CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TAK-079. CAS No. 2227490-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99730.
Mezigdomide
Mezigdomide (CC-92480), a cereblon E3 ubiquitin ligase modulating agent (CELMoD), acts as a molecular glue. Mezigdomide shows high affinity to cereblon, resulting in potent antimyeloma activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-92480. CAS No. 2259648-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129395.
Mezlocillin
Mezlocillin. Group: Biochemicals. Grades: Highly Purified. CAS No. 51481-65-3. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Mezlocillin sodium
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Mezlocillin sodium
100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C21H24N5NaO8S2. CAS No. 59798-30-0. Prepack ID 77075760-100mg. Molecular Weight 561.56. See USA prepack pricing.
Mezlocillin sodium
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-f 1353 sodium. CAS No. 42057-22-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1466.
Mezlocillin Sodium
Mezlocillin Sodium. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
MF-094
MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241025-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112438.
Mfa-hst5
Mfa-hst5 is from Macaca fascicularis and has antifungal, Candida spp. and Criptococcus spp. activities.
MF-EA-705alpha
It is originally isolated from Streptomyces sp. MF-EA-705. And the MIC of MF-EA-705alpha against Candida albicans was 1 g/mL. Molecular formula: C20H22O2. Mole weight: 294.39.
MF-EA-705beta
MF-EA-705beta is an antifungal antibiotic isolated from Streptomyces sp. MF-EA-705. Synonyms: (3E,5E,7Z)-8-{2-[(1Z)-but-1-en-1-yl]-4-methylphenyl}nona-3,5,7-trienoic acid. Molecular formula: C20H24O2. Mole weight: 294.39.
Mfe I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑AATTG GTTAA↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Mfe I from Mycoplasma fermentans. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1131RE.
MFI8
MFI8 is a small molecule inhibitor of mitochondrial[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 694488-83-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150031.
m-Fluoro-DL-phenylalanine
m-Fluoro-DL-phenylalanine. Uses: Cell analysis peptide synthesis. Additional or Alternative Names: 3-Fluoro-DL-phenylalanine. Product Category: Amino Acids. CAS No. 456-88-2. Molecular formula: FC6H4CH2CH(NH2)COOH. Mole weight: 183.18. Canonical SMILES: NC(Cc1cccc(F)c1)C(O)=O. ECNumber: 220-104-1. Product ID: ACM456882-1. Alfa Chemistry ISO 9001:2015 Certified.
m-Fluoro Prasugrel Thiolactone. (Mixture of Diastereomers)
Intermediate in the synthesis of m-Fluoro Prasugrel (F595870). Group: Biochemicals. Alternative Names: 5-[2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7. Group: Biochemicals. Grades: Purified. CAS No. 1224431-15-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MFZ 10-7
MFZ 10-7 is a highly potent and selective mGluR5 NAM (negative allosteric modulator), with a K i of 0.67 nM for rat mGluR5 [1]. MFZ 10-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1224431-15-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103575.
MG 101
MG 101. Group: Biochemicals. Grades: Purified. CAS No. 110044-82-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
MG-101
MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with K i s of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor I; Ac-LLnL-CHO; ALLN. CAS No. 110044-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18964.
MG-115 - CAS 133407-86-0
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Group: Fluorescence/luminescence spectroscopy.
A potent, reversible proteasome inhibitor with Ki of 21nM for 20S proteasome and 35nM for 26S proteasome. The inhibition of proteasome was through specific inhibition of chymotrypsin-like activity of the proteasome. Also shown to induce apoptosis in Rat-1 and PC12 cells via a p3-independent pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
MG-132
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC 50 s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Leu-Leu-Leu-al; MG132. CAS No. 133407-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13259.
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). Group: Fluorescence/luminescence spectroscopy.
MG-132 - CAS 133407-82-6
A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM). Group: Fluorescence/luminescence spectroscopy.
MG-132 (negative control)
MG-132 negative control is the negative control form of MG-132 (HY-13259). MG-132 is a potent proteasome and calpain inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13259D.
MG-132 (Z-Leu-Leu-Leu-CHO)
Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kB activation inhibitor through IκB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin inhibitor. Has anticancer properties by inducing cell cycle arrest and activating apoptosis in various cancer cell lines. Has adjuvant / chemosensitizer potential. Neurite outgrowth stimulator in PC12 cells. Prevents beta-secretase cleavage. Autophagy activator. Group: Biochemicals. Alternative Names: Z-Leu-Leu-Leu-al; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal; Proteasome Inhibitor XI). Grades: Highly Purified. CAS No. 133407-82-6. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H41N3O5, Sequence: Z-Leu-Leu-Leu-aldeyhde. US Biological Life Sciences.
Worldwide
MG 149
MG 149. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1243583-85-8. Molecular formula: C22H28O3. Mole weight: 340.46. Catalog: APB1243583858.
MG 149
MG149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF (IC50= 47 uM); little potent for PCAF and p300 (IC50 >200 uM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tip60 HAT inhibitor. CAS No. 1243583-85-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15887.