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| Product | Description | |
|---|---|---|
| Mivacurium Chloride Impurity 31 | Mivacurium Chloride Impurity 31. Uses: For analytical and research use. Alternative Names: 6,7-dimethoxy-1-(3,4,5-trimethoxybenzyl)-3,4-dihydroisoquinoline-2(1H)-carbaldehyde. Molecular formula: C22H27NO6. Mole weight: 401.18. Catalog: APB01477. |  |
| Mivacurium Chloride Impurity 31 | Mivacurium Chloride Impurity 31. Uses: For analytical and research use. CAS No. 117676-61-6. Molecular formula: C25H36ClNO6. Mole weight: 482.01. Catalog: APB117676616. | |
| Mivacurium Chloride Impurity 4 | Mivacurium Chloride Impurity 4. Uses: For analytical and research use. CAS No. 714192-43-5. Molecular formula: C33H46NO9+. Mole weight: 600.73. Catalog: APB714192435. | |
| Mivacurium Chloride Impurity 46 | Mivacurium Chloride Impurity 46. Uses: For analytical and research use. Alternative Names: (E)-di-tert-butyl oct-4-enedioate. Molecular formula: C16H28O4. Mole weight: 284.39. Catalog: APB01476. | |
| Mivacurium Chloride Impurity 47 | Mivacurium Chloride Impurity 47. Uses: For analytical and research use. Alternative Names: (E)-8-(tert-butoxy)-8-oxooct-4-enoic acid. Molecular formula: C12H20O4. Mole weight: 228.28. Catalog: APB01475. | |
| Mivacurium Chloride Impurity 5 | Mivacurium Chloride Impurity 5. Uses: For analytical and research use. CAS No. 7668-85-1. Molecular formula: C25H36NO6+. Mole weight: 446.56. Catalog: APB7668851. | |
| Mivacurium Chloride Impurity 6 | Mivacurium Chloride Impurity 6. Uses: For analytical and research use. Molecular formula: C25H36NO6+. Mole weight: 446.56. Catalog: APB10663. | |
| Mivacurium Chloride Impurity 7 | Mivacurium Chloride Impurity 7. Uses: For analytical and research use. Molecular formula: C33H46NO9+. Mole weight: 600.73. Catalog: APB10664. | |
| Mivacurium Chloride Impurity 8 | Mivacurium Chloride Impurity 8. Uses: For analytical and research use. Molecular formula: C33H46NO9+. Mole weight: 600.73. Catalog: APB10665. | |
| Mivacurium Chloride Impurity 9 | Mivacurium Chloride Impurity 9. Uses: For analytical and research use. Molecular formula: C36H51Cl2NO9. Mole weight: 712.7. Catalog: APB10666. | |
| Mivacurium Chloride Impurity A | Mivacurium Chloride Impurity A. Uses: For analytical and research use. Alternative Names: (1R,2S)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-66-9. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740669. | |
| Mivacurium Chloride Impurity B | Mivacurium Chloride Impurity B. Uses: For analytical and research use. Alternative Names: (1R,2R)-2-(3-hydroxypropyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. CAS No. 107740-64-7. Molecular formula: C25H36NO6·Cl. Mole weight: 482.01. Catalog: APB107740647. | |
| Mivacurium Chloride Impurity C | Mivacurium Chloride Impurity C. Uses: For analytical and research use. Alternative Names: (1R,2S)-2-(3-(((E)-7-carboxyhept-4-enoyl)oxy)propyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. Molecular formula: C33H46NO9·Cl. Mole weight: 636.17. Catalog: APB02030. | |
| Mivacurium Chloride Impurity D | Mivacurium Chloride Impurity D. Uses: For analytical and research use. Alternative Names: (1R,2R)-2-(3-(((E)-7-carboxyhept-4-enoyl)oxy)propyl)-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride. Molecular formula: C33H46NO9·Cl. Mole weight: 636.17. Catalog: APB02031. | |
| Mivacurium Chloride (mixture of isomers) | Non-depolarizing neuromuscular blocking agent. Muscle relaxant (skeletal). Group: Biochemicals. Alternative Names: (1R, 1'R) -2, 2'-[[ (4E) -1, 8-Dioxo-4-octene-1, 8-diyl]bis (oxy-3, 1-propanediyl) ]bis[1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-2-methyl-1-[ (3, 4, 5-trimethoxyphenyl) methyl]-isoquinolinium Chloride ; Mivacron; BW-B 1090U. Grades: Highly Purified. CAS No. 106861-44-3. Pack Sizes: 2.5mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??Cl?N?O??, Molecular Weight: 1100.17. US Biological Life Sciences. |  Worldwide |
| Mivavotinib monohydrochloride | TAK-659 hydrochloride is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 hydrochloride induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-659 monohydrochloride; CB-659 monohydrochloride. CAS No. 1952251-28-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100867A. |  |
| Mivebresib | Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-075. CAS No. 1445993-26-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100015. | |
| MIXED AMINOPHENETHYL ALCOHOL | MIXED AMINOPHENETHYL ALCOHOL. Product ID: ACMA00009049. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Mixed amino resin | Mixed amino resin. |  |
| MIXED ISOPROPANOLAMINES LAURYL SULFATE | MIXED ISOPROPANOLAMINES LAURYL SULFATE. CAS No. 68877-25-8. Product ID: ACM68877258. Alfa Chemistry - ISO 9001:32057 Certified. | |
| MIXED ISOPROPANOLAMINES MYRISTATE | MIXED ISOPROPANOLAMINES MYRISTATE. Product ID: ACMA00005783. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Mixed Tocopherol 70% | Mixed Tocopherol 70%. CAS No. 1406-66-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Mixed tocopherol microencapsulated powder | Mixed tocopherol microencapsulated powder. Product ID: CDF4-0195. Molecular formula: NA. Category: Antioxidant; nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0195; Mixed tocopherol microencapsulated powder; Antioxidant; nutrient supplements. Appearance: light yellow powder. Color: light yellow. Physical State: powder. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| Mixed Tocopherols | Mixed Tocopherols. CAS No: 1406-18-4 |  Sarchem Laboratories New Jersey NJ |
| Mixture of d-propylamine-c disubstituted impurity + disubstituted ring closing impurity | Mixture of d-propylamine-c disubstituted impurity + disubstituted ring closing impurity. Uses: For analytical and research use. Molecular formula: C14H26N4O7. Mole weight: 362.38. Catalog: APB07514. | |
| Miyakamide A1 | Miyakamide A1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A1 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 10.5 μg/mL. CAS No. 497252-38-7. Molecular formula: C31H32N4O3. Mole weight: 508.61. |  |
| Miyakamide A2 | Miyakamide A2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide A2 inhibits the growth of Artemia salina at a minimum concentration of 5 μg/mL. Miyakamide A1 has weak antixanthomonas activity. It inhibits P388 cells with an IC50 of 12.2 μg/mL. CAS No. 497252-39-8. Molecular formula: C31H32N4O3. Mole weight: 508.61. | |
| Miyakamide B1 | Miyakamide B1 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B1 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 8.8 μg/mL. CAS No. 497182-82-8. Molecular formula: C31H32N4O4. Mole weight: 524.61. | |
| Miyakamide B2 | Miyakamide B2 is an antibiotic produced by Aspergillus flavus var. columnaris FKI-0739. It has insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina at a minimum concentration of 20 μg/mL. It inhibits P388 cells with an IC50 of 7.6 μg/mL. CAS No. 497182-83-9. Molecular formula: C31H32N4O4. Mole weight: 524.61. | |
| Mizacorat | Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD9567. CAS No. 1893415-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-120012. | |
| Mizagliflozin | Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DSP-3235 free base; KGA-3235 free base; GSK-1614235 free base. CAS No. 666843-10-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17638. | |
| Mizolastine | A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticaria. Group: Biochemicals. Alternative Names: 2- [ [1- [1- [ (4-Fluorophenyl) methyl] -1H-benzimidazol-2-yl] -4-piperidinyl] methylamino] - 4(1H)-pyrimidinone; MKC 431; Mistamine; Mizollen; SL 850324; Zolistan. Grades: Highly Purified. CAS No. 108612-45-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Mizolastine | Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. Category: Active pharmaceutical ingredients. CAS No. 108612-45-9. Product ID: API108612459. Molecular formula: C24H25FN6O. Mole weight: 432.49. |  |
| Mizolastine | Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. Uses: Histamine h1 antagonists, non-sedating. Synonyms: Mizollen; SL 850324; SL850324; SL-850324; Mistalin; Mistamine; Mizolastina; Mizolastine. Grade: >98%. CAS No. 108612-45-9. Molecular formula: C24H25FN6O. Mole weight: 432.49. | |
| Mizolastine dihydrochloride | Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM). It also used in the treatment of hay fever, hives, and other allergic reactions. Category: Active pharmaceutical ingredients. CAS No. 1056596-82-7. Product ID: API1056596827. Molecular formula: C24H27Cl2FN6O. Mole weight: 505.42. | |
| Mizoribine | Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC50 of approximately 100 μM for anti-HCV activity. Immunosuppressant[1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC50s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 289637; HE 69. CAS No. 50924-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17470. | |
| Mizoribine | Mizoribine. Group: Biochemicals. Alternative Names: 1-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide. Grades: Highly Purified. CAS No. 50924-49-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C9H13N3O6. US Biological Life Sciences. | Worldwide |
| Mizoribine | Bredinin is a nucleoside antibiotic produced by Eupenicillum brefeldianum M-2166. It has anti-L-5178Y cell and anti-pox virus activity, not against bacteria and fungi. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: N'-(b-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide; Bredinin; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxy-1H-imidazole-4-carboxamide; 5-Hydroxy-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide. Grade: ≥95%. CAS No. 50924-49-7. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| MJ347-81F4-B | MJ347-81F4-B is originally isolated from Amycolatopsis sp. MJ347-81F4. It has good anti-gram-positive bacteria activity, including clinically isolated methicillin-resistant Staphylococcus aureus (MIC 0.05-0.2 μg/mL). Molecular formula: C60H58N14O18S5. Mole weight: 1423.51. | |
| MJN110 | MJN110 is an orally active and selective monoacylglycerol lipase (MAGL) inhibitor with IC50s of 9.1 nM and 2.1 nM for hMAGL and 2-arachidonoylglycerol (2-AG), respectively[1]. MJN110 produces opioid-sparing effects and displays strong antihyperalgesic activity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1438416-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117474. | |
| MK-0159 | MK-0159 is an orally active, potent and selective CD38 inhibitor, with IC50 values of 22, 3, and 70 nM for human, mouse and rat CD38, respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD+ (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2641484-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150508. | |
| MK 0343 | MK 0343. Group: Biochemicals. Grades: Purified. CAS No. 233275-76-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-0343 | MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MRK-409. CAS No. 233275-76-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101869. | |
| MK-0354 | MK-0354 is a specific GPR109a receptor agonist with EC50 values of 1.65 μM and 1.08 μM for hGPR109a and mGPR109a, respectively. MK-0354 can be used in liver cancer research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851776-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13008. | |
| MK-0429 | MK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide pan-integrin antagonist with IC50 values of 1.6 nM, 2.8 nM, 0.1 nM, 0.7 nM, 0.5 nM and 12.2 nM for αvβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-000845704. CAS No. 227963-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15102. | |
| MK-0493 | MK-0493 is an orally active melanocortin-4 receptor (MC4R) agonist. MK-0493 reduces food intake, suppresses weight gain, elevates blood pressure at high doses, and exhibits preclinical erectile regulatory activity. MK-0493 can be used in research related to obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 455956-93-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118930. | |
| MK-0557 | MK-0557 is a highly selective, orally available neuropeptide Y5 receptor antagonist with a Ki of 1.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 328232-95-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15411. | |
| MK-0608 | MK-0608 is a potent and orally bioavailable inhibitor of HCV replication in vitro with an EC50 of 0.3 μM (EC90=1.3 μM) in the subgenomic-replicon assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 443642-29-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10244. | |
| MK 0677 | MK 0677. Group: Biochemicals. Grades: Purified. CAS No. 159752-10-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-0731 | MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845256-65-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-50672. | |
| MK-0752 | MK-0752 is a gamma secretase inhibitor in clinical development. Group: Biochemicals. Alternative Names: cis-4-[ (4-Chlorophenyl) sulfonyl]-4- (2, 5-difluorophenyl) cyclohexanepropanoic Acid. Grades: Highly Purified. CAS No. 471905-41-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MK-0752 | MK-0752 is a potent, orally active and specific γ-secretase inhibitor, showing dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells. MK-0752 crosses the blood-brain barrier. MK-0752 reduces newly generated CNS Aβ in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 471905-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10974. | |
| MK-0773 | MK-0773 is a selective androgen receptor modulators (SARMs) that binds to AR with an IC50 of 6.6 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-05314882. CAS No. 606101-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11027. | |
| MK 0812 | MK 0812. Group: Biochemicals. Grades: Highly Purified. CAS No. 624733-88-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| MK-0812 | MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2. Uses: Scientific research. Category: Signaling pathways. CAS No. 624733-88-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-50669. | |
| MK-0812 Succinate | MK-0812 Succinate is a potent and selective CCR2 antagonist with high affinity at CCR2. Uses: Scientific research. Category: Signaling pathways. CAS No. 851916-42-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-50669A. | |
| MK 0893 | MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 870823-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50663. | |
| MK-1064 | MK-1064 is a selective and orally active OX2R antagonist (Ki: 0.5 nM, IC50: 18 nM). MK-1064 promotes sleep in vivo. MK-1064 can be used in the research of insomnia[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1207253-08-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19914. | |
| MK 1903 | MK 1903. Group: Biochemicals. Grades: Purified. CAS No. 1268882-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-1903 | MK-1903 is an orally active full agonist of GPR109a/HCAR2, with an EC50 of 12.9 nM. MK-1903 activates antilipolytic and vasodilatory pathways, reduces plasma free fatty acid levels, and induces skin flushing. MK-1903 stimulates the expression of HCAR2 protein and regulates the inflammatory response of microglia. MK-1903 prevents the enhanced firing activity of spinal nociceptive neurons. MK-1903 triggers the release of MMP-9 and the formation of NET. MK-1903 can be used in the research of dyslipidemia and neuroinflammation-based central nervous system diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1268882-43-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107581. | |
| MK-2048 | MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir. MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir. Group: Biochemicals. Alternative Names: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-1, 2, 6, 7, 8, 9-hexahydropyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide. Grades: Highly Purified. CAS No. 869901-69-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MK 212 hydrochloride | MK 212 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 61655-58-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MK-2206 | MK-2206 is an orally active pan-AKT inhibitor, with IC50 values of 8 nM, 12 nM and 65 nM against AKT1, AKT2 and AKT3, respectively. MK-2206 inhibits the Akt/mTOR signaling pathway and reduces the levels of downstream GSK3β and Mcl-1 via proteasomal degradation. MK-2206 induces G1-phase cell cycle arrest, apoptosis, epithelial-mesenchymal transition, fibroblast activation and extracellular matrix deposition. MK-2206 causes transient hyperglycemia and hyperinsulinemia in animals. MK-2206 can be used in research related to solid tumors, renal fibrosis and hypercholesterolemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1032349-77-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-108232. | |
| MK-2206 | MK-2206 Inhibitor. Uses: Scientific use. Product Category: T1952. CAS No. 1032350-13-2. |  |
| MK-2206 dihydrochloride | MK-2206 dihydrochloride (MK-2206 2HCl) is an orally active pan-AKT inhibitor, with IC50 values of 8 nM, 12 nM and 65 nM against AKT1, AKT2 and AKT3, respectively. MK-2206 dihydrochloride inhibits the Akt/mTOR signaling pathway and reduces the levels of downstream GSK3β and Mcl-1 via proteasomal degradation. MK-2206 dihydrochloride induces G1-phase cell cycle arrest, apoptosis, epithelial-mesenchymal transition, fibroblast activation and extracellular matrix deposition. MK-2206 dihydrochloride causes transient hyperglycemia and hyperinsulinemia in animals. MK-2206 dihydrochloride can be used in research related to solid tumors, renal fibrosis and hypercholesterolemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-2206 (2HCl). CAS No. 1032350-13-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10358. | |
| MK-2206 dihydrochloride | MK-2206 dihydrochloride. Group: Biochemicals. Alternative Names: 8-[4- (1-Aminocyclobutyl) phenyl]-9-phenyl-1, 2, 4-triazolo[3, 4-f][1, 6]naphthyridin-3 (2H) -one hydrochloride. Grades: Highly Purified. CAS No. 1032350-13-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C25H23Cl2N5O. US Biological Life Sciences. | Worldwide |
| MK-2206 Dihydrochloride | MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2. Group: Inhibitors. CAS No. 1032350-13-2. Pack Sizes: 5mg. Product ID: S1078. Formula: C25H21N5O.2HCl. Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| MK-2461 | MK-2461 is an ATP-competitive, selective and orally active wild-type and mutant c-Met inhibitor (IC50s: 0.4-2.5 nM). MK-2461 also inhibits Ron (IC50 of 7 nM) and Flt1 (IC50 of 10 nM), MK-2461 shows selective for c-MET over other kinases (lC50s = 22-7800 nM). MK-2461 can be used for the study of cancer, such as gastric cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 917879-39-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50703. | |
| MK-28 | MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864388-65-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-137207. | |
| MK-2894 | MK-2894 is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1006036-87-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10413. | |
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