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| Product | Description | |
|---|---|---|
| MSTFA Reagent | MSTFA Reagent. Uses: For analytical and research use. CAS No. 24589-78-4. Mole weight: 199.25. EC Number: 246-331-6. Catalog: AP24589784-A. |  |
| MSU38225 | MSU38225 is an Nrf-2 inhibitor that increases levels of reactive oxygen species (ROS). MSU38225 inhibits the growth of human lung cancer cells and enhances the sensitivity of human lung cancer cells to chemotherapy in vitro and in vivo. MSU38225 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629160-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153873. |  |
| MSX-122 | MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ?10 nM. MSX-122 has anti-inflammatory and anti-metastatic activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 897657-95-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13696. | |
| MT1 | MT1 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0.789 nM for BRD4(1)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2060573-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111976. | |
| MT-110 | MT-110 (BPN-0027490) is a non-muscle myosin NMIIB-selective inhibitor with high brain penetration and favorable safety profile. MT-110 specifically disrupts NMIIB-dependent actin dynamics in dendritic spines, while it exerts no significant adverse effects on cardiac myosin II and cardiac functions (such as cardiac output and heart rate) at tested concentrations. A single administration of MT-110 produces long-lasting (sustained for several weeks) blockade of methamphetamine motivation associated with environmental cues. MT-110 exhibits extremely high specificity, with no interference with cocaine motivation, hippocampus-dependent memory, fear memory, or locomotor and anxiety-like behaviors. MT-110 serves as a valuable tool compound for investigating the mechanisms of methamphetamine use disorder[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPN-0027490. CAS No. 2404652-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175188. | |
| MT-125 free base | MT-125 free base is a specific and well-tolerated inhibitor of non-muscle myosin IIA (Ki,NMIIA = 2.7 μM) and IIB (EC50 = 1.7 μM). MT-125 free base can pass through the blood-brain barrier. MT-125 free base induces ferroptosis and DNA damage by increasing the levels of reactive oxygen species (ROS) within tumor cells. MT-125 free base can enhance the PDGFR signaling pathway. MT-125 free base can be used for research on glioblastoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2404652-80-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-174406A. | |
| MT1-MMP Inhibitor, NSC405020 (3,4-Dichloro-N-(1-methylbutyl)benzamide, 3,4-Dichloro-N-(pentan-2-yl)benzamide) | A cell-permeable pentanylbenzamide compound that acts as an allosteric, reversible, and selective inhibitor of the collgenolytic activity of MT1-MMP. Does not affect the catalytic activity of cellular MT-1-MMP thus allows it to retain its ability to activate MMP-2. Selectively targets the hemopexin (PEX) domain of MT1-MMP, thereby repressing its pro-tumorigenic activity. Its binding to the PEX domain is dependent on Met-328, Arg-330, Asp-376, Met-422, and Ser-470 in the druggable pocket of the enzyme. Shown to block 184B5-MT cell migration on collagen-1 and repress MCF7-b3/MT tumor growth in xenografted mice (0.5mg/kg, intratumoral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| MT-228 | MT-228 (BPN-0026709) is a selective and blood-brain barrier permeable non-muscle myosin II inhibitor. MT-228 markedly improves tolerability by selectively targeting NMIIB (KI = 1.5 μM) over CMII (KI = 17 μM), and the sequence of SmMll MD is 83.6% identical to that of NMllB. MT-228 shows long-lasting efficacy in animal models of stimulant use disorder[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPN-0026709. CAS No. 2404652-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175199. | |
| MT-4 | MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel. Uses: Scientific research. Category: Signaling pathways. CAS No. 2327925-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128595. | |
| MT 63-78 | MT 63-78 is a specific and potent direct AMPK activator with an EC50 of 25 μM. MT 63-78 also induces cell mitotic arrest and apoptosis. MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1179347-65-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W058849. | |
| MT-802 | MT-802 is a BTK PROTAC degrader. MT-802 degrades wild-type BTK (DC50 = 14.6 nM) and BTK mutants including E41K, C481S (DC50 = 14.9 nM), C481R, C481Y, C481T, C481F, L528W, and inhibits their Y223 phosphorylation. BI-4732 can be used for the study of Ibrutinib (HY-10997)-resistant chronic lymphocytic leukemia (CLL). (Pink: BTK ligand (HY-150885), Blue: CRBN Ligand (HY-14658), Black: Linker (HY-141371), E3 ligase ligand-linker conjugate (HY-176340))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2231744-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122562. | |
| MT 81 | MT 81 is a plant toxin that comes from Penicillum nigricans. It has anti-Gram-positive bacteria activity. Synonyms: Mycotoxin 81; Mycotoxin MT 81; MT81; BRN 4596898; 1,5-Dihydroxy-3-methyl-8-[(2,6,7,7a-tetrahydro-4H-furo[3,2-c]pyran-4-yl)oxy]-9,10-anthracenedione. CAS No. 93513-59-8. Molecular formula: C22H18O7. Mole weight: 394.37. |  |
| MTBE | MTBE. CAS No. 1634-04-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| MT-DADMe-ImmA | MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTDIA; Methylthio-DADMe-Immucillin A. CAS No. 653592-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101496. | |
| MTDH-SND1 blocker 1 | MTDH-SND1 blocker 1 (compound C26-A6) is an inhibitor of the MTDH-SND1 protein. MTDH-SND1 blocker 1 inhibits cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1341030-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155170. | |
| MTEP | Potent and selective antagonist for mGluR5. 5-fold higher anxiolytic activity than MPEP. Antidepressant. Neuroprotective. Produces anti-parkinsonian-like effects in rats. Group: Biochemicals. Alternative Names: 3-pyridine. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H8N2S. US Biological Life Sciences. | Worldwide |
| MTEP hydrochloride | MTEP hydrochloride is a potent, non-competitive and highly selective mGluR5 antagonist, with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. MTEP hydrochloride can be used for Parkinson's disease research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1186195-60-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13206. | |
| MTEP Hydrochloride | MTEP Hydrochloride. Group: Biochemicals. Alternative Names: 3-[ (2-Methyl-4-thiazolyl) ethynyl]pyridine; 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Hydrochloride. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 10mg. Molecular Formula: C11H9ClN2S, Molecular Weight: 236.72. US Biological Life Sciences. | Worldwide |
| MTEP Hydrochloride (3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine Hydrochloride) | A non-competitive, potent antagonist highly selective for mGlu5 receptors (IC50 = 5nM). Biologically active admitted orally or systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1186195-60-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| m-Terphenyl | White powder, 99%. Synonym: 1,3-Diphenylbenzene. CAS No. 92-06-8. Pack Sizes: Typically in stock: 50g, 250g. Mole weight: 230.31. MP/BP: M.P. 87. Order No: FR-3040. |  Frinton Laboratories |
| M-Terphenyl | M-terphenyl is a yellow solid. mp: 86-87° C, bp: 365°C. Density: 1.195 g/cm³. Insoluble in water. Usually shipped as a solid mixture with its isomers o-terphenyl and p-terphenyl that is used as a heat-transfer fluid.;Colorless or light-yellow solid.;Yellow solid (needles). Alternative Names: m-Diphenylbenzene. CAS No. 92-06-8. Molecular formula: C18H14. Mole weight: 230.3. Purity: 99%. IUPAC Name: 1,3-Diphenylbenzene. SMILES: C1=CC=C(C=C1)C2=CC(=CC=C2)C3=CC=CC=C3. InChI: InChI=1S/C18H14/c1-3-8-15(9-4-1)17-12-7-13-18(14-17)16-10-5-2-6-11-16/h1-14H. |  |
| m-Terphenyl-2'-ol | m-Terphenyl-2'-ol. CAS No. 2432-11-3. Molecular formula: C18H14O. Mole weight: 246.3g/mol. IUPAC Name: 2,6-diphenylphenol. SMILES: C1=CC=C(C=C1)C2=C(C(=CC=C2)C3=CC=CC=C3)O. InChI: InChI=1S/C18H14O/c19-18-16(14-8-3-1-4-9-14)12-7-13-17(18)15-10-5-2-6-11-15/h1-13,19H. | |
| mTERT (572-580) | A peptide fragment of mTERT. Mouse telomerase reverse transcriptase (mTERT) is a gene that is expressed by cells that need to continually divide without the characteristic shortening of telomeres that accompanies DNA replication. Synonyms: hTERT R572Y peptide; Mouse telomerase reverse transcriptase (572-580). | |
| Mth-dl-glutamic acid | Mth-dl-glutamic acid. CAS No. 1801-64-5. Purity: 96%. Product ID: ACM1801645. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| M-theraphotoxin-Gr1a | This cationic hydrophobic peptide inhibits a lot of different channels and has an antimicrobial activity. It also exhibits antimicrobial activities against the Gram-positive bacteria B.subtilis (MIC=0.5 μM), S.aureus (MIC=2-4 μM), and S.epidermidis (MIC=4-8 μM), and Gram-negative bacteria S.typhimurium (MIC=32.64 μM), P.aeruginosa (MIC=8-16 μM), and E.coli (MIC=8-16 μM). Synonyms: M-TRTX-Gr1a; GsMTx-4. | |
| MTHPA (Methyl Tetrahydrophthalic Anhydride) | MTHPA (Methyl Tetrahydrophthalic Anhydride). | |
| m-threo-chloramphenicol | m-threo-chloramphenicol. Group: Biochemicals. Alternative Names: Dichloro-N-[2-hydroxy-1- (hydroxymethyl) -2- (3-nitrophenyl) ethyl]acetamide. Grades: Highly Purified. CAS No. 7411-65-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C11H12Cl2N2O5. US Biological Life Sciences. | Worldwide |
| MTI-31 | MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding assays. MTI-31 shows an IC50 of 39 nM for mTOR in LANCE assay of mTOR substrate phosphorylation with 100 μM ATP. MTI-31 can be used for the research of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LXI-15029. CAS No. 1567915-38-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126077. | |
| MTIC-d3 (Monomethyl-d3 Triaizeno Imidazole Carboxamide, 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide, 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide, NSC 407347-d3) | A labeled metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl-d3 Triaizeno Imidazole Carboxamide; 3-Methyl-d3-(triazenyl)imidazole-4-carboxamide; 5-(3-Methyl-d3-triazen-1-yl)imidazole-4-carboxamide; NSC 407347-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MTIC (Monomethyl Triaizeno Imidazole Carboxamide) | A metabolite of Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: Monomethyl Triaizeno Imidazole Carboxamide; 3-Methyl (triazenyl)imidazole-4-carboxamide; 5- (3-Methyltriazen-1-yl)imidazole-4-carboxamide, NSC 407347. Grades: Highly Purified. CAS No. 3413-72-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| MTK458 | MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EP-0035985. CAS No. 2499962-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152943. | |
| MTOB sodium | MTOB sodium is a potent C-terminal binding protein (CtBP) inhibitor. MTOB sodium attenuates repetitive head injury-elicited neurologic dysfunction and neuroinflammation via inhibition of the transactivation activity of CtBP1 and CtBP2. MTOB sodium antagonizes the transcriptional regulatory activity of CtBP1 and CtBP2 by eviction from their target promoters in breast cancer cell lines[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 51828-97-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-135046. | |
| m-Tolidine | m-Tolidine. CAS No. 84-67-3. Molecular formula: C14H16N2. Mole weight: 212.29g/mol. IUPAC Name: 4-(4-amino-2-methylphenyl)-3-methylaniline. SMILES: CC1=C(C=CC(=C1)N)C2=C(C=C(C=C2)N)C. InChI: InChI=1S/C14H16N2/c1-9-7-11(15)3-5-13(9)14-6-4-12(16)8-10(14)2/h3-8H,15-16H2,1-2H3. | |
| m-Tolualdehyde | m-Tolualdehyde. Alternative Names: 3-Methylbenzaldehyde. CAS No. 620-23-5. Purity: >97.0%. Product ID: FFC-AR-620235. Molecular formula: C8H8O. Mole weight: 120.15. IUPAC Name: 3-methylbenzaldehyde. Alfa Chemistry - ISO 9001:32057 Certified. | |
| M-toluene sulfonic acid impurity 3 | M-toluene sulfonic acid impurity 3. Uses: For analytical and research use. CAS No. 617-97-0. Molecular formula: C7H8O3S. Mole weight: 172.2. Catalog: APB617970. | |
| m-Toluic acid | 500g Pack Size. Group: Building Blocks, Organics. Formula: C8H8O2. CAS No. 99-04-7. Prepack ID 90029790-500g. Molecular Weight 136.15. See USA prepack pricing. |  |
| m-Toluic acid | 1kg Pack Size. Group: Building Blocks, Organics. Formula: C8H8O2. CAS No. 99-04-7. Prepack ID 90029790-1kg. Molecular Weight 136.15. See USA prepack pricing. | |
| m-Toluic Acid | M-toluic acid appears as white to yellowish crystals or mostly yellow flaky solid (with some white flakes). Has a floral-honey odor. (NTP, 1992);DryPowder; PelletsLargeCrystals. Molecular formula: C8H8O2. Mole weight: 136.15g/mol. IUPAC Name: 3-methylbenzoic acid. SMILES: CC1=CC(=CC=C1)C(=O)O. InChI: InChI=1S/C8H8O2/c1-6-3-2-4-7(5-6)8(9)10/h2-5H,1H3,(H,9,10). | |
| M-Toluic acid | M-Toluic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 99-04-7. Pack Sizes: 500g, 1kg, 2kg, 5kg. Molecular Formula: C8H8O2. US Biological Life Sciences. | Worldwide |
| m-Toluic Acid-[d7] | m-Toluic Acid-[d7]. Synonyms: m-Toluic-d7 Acid; 3-(2H3)Methyl(2H4)benzoic acid. Grade: 98% atom D. CAS No. 733046-94-1. Molecular formula: C8HD7O2. Mole weight: 143.19. | |
| m-Toluidine | m-Toluidine. Group: Biochemicals. Alternative Names: 3-Methylaniline. Grades: Highly Purified. CAS No. 108-44-1. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: CH3C6H4NH2. US Biological Life Sciences. | Worldwide |
| m-Toluquinoline | m-Toluquinoline. Group: Biochemicals. Alternative Names: 7-Methyl-quinoline; 7-Methylquinoline; NSC 65665. Grades: Highly Purified. CAS No. 612-60-2. Pack Sizes: 2.5g. Molecular Formula: C9H10N, Molecular Weight: 143.19. US Biological Life Sciences. | Worldwide |
| m-Tolyl acetate | m-Tolyl acetate. Group: Biochemicals. Alternative Names: Acetic acid 3-methylphenyl ester. Grades: Highly Purified. CAS No. 122-46-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H10O2. US Biological Life Sciences. | Worldwide |
| m-Tolylacetic acid | m-Tolylacetic acid. Alternative Names: 3-Methylphenylacetic acid. CAS No. 621-36-3. Purity: >98.0%. Product ID: FFC-AR-621363. Molecular formula: C9H10O2. Mole weight: 150.17. IUPAC Name: 2-(3-methylphenyl)acetic acid. Alfa Chemistry - ISO 9001:32057 Certified. | |
| m-Tolylacetyl chloride | m-Tolylacetyl chloride. Alternative Names: M-TOLYL-ACETYL CHLORIDE. CAS No. 13910-79-7. Product ID: ACM13910797. Molecular formula: C9H9ClO. Mole weight: 168.62. Alfa Chemistry - ISO 9001:32057 Certified. | |
| m-tolyl adamantane-1-carboxylate | m-tolyl adamantane-1-carboxylate. Category: Active pharmaceutical ingredients. CAS No. 73599-99-2. Product ID: API73599992. Molecular formula: C18H22O2. Mole weight: 270.366. |  |
| m-Tolylboronic acid MIDA ester | m-Tolylboronic acid MIDA ester. | |
| m-Tolylurea | m-Tolylurea. Group: Biochemicals. Grades: Highly Purified. CAS No. 63-99-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| m-Topolin | m-Topolin. Group: Biochemicals. Alternative Names: 6- (3-Hydroxybenzylamino) purine. Grades: Highly Purified. CAS No. 75737-38-1. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C12H11N5O. US Biological Life Sciences. | Worldwide |
| mTOR Activator, MHY1485 (4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine, Autophagy Inhibitor III) | A cell-permeable triazine derivative that is shown to increase cellular mTOR Ser2448 and downstream substrate 4E-BP Thr37/46 phosphorylation level in rat liver Ac2F cells (1 to 2uM for 1h), affecting culture viability only at much higher concentrations (by 20% after 24h 20uM treatment). MHY1485 induced cellular LC3-II accumulation in Ac2F is reported to be a result of autophagy inhibition due to reduced fusion between autophagosomes and lysosomes. The mechanism of mTOR activation by MHY1485 is currently unknown. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| mTOR Antibody [C15M14] | mTOR Antibody [C15M14]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0169. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| mTOR inhibitor-3 | mTOR inhibitor-3 is a remarkably selective mTOR inhibitor with a Ki of 1.5 nM. mTOR inhibitor-3 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK)/pharmacodynamic (PD) experiments. Uses: Scientific research. Category: Signaling pathways. CAS No. 1207358-59-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18353. | |
| mTOR Inhibitor, Ku-0063794 (rel-5- [2- [ (2R, 6S) -2, 6-Dimethyl-4-morpholinyl] -4- (4-morpholinyl) pyrido [2, 3-d] pyrimidin-7-yl] -2-methoxy Benzene methanol) | A potent mTOR (mammalian target of rapamycin) inhibitor (IC?? =~10nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested. Group: Biochemicals. Grades: Highly Purified. CAS No. 938440-64-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| mTOR Inhibitor XII, Torin2 (9- (6-aminopyridin-3-yl) -1- (3- (trifluoromethyl) phenyl) benzo[h][1, 6]naphthyridin-2 (1H) -one, DNA-PK Inhibitor VII, PI 3-K Inhibitor XIX, PI 4-K Inhibitor) | A Torin1 structural analog that acts as a cell-permeable, potent, ATP-competitive inhibitor against DNA-PK and mTOR (IC50 = 0.5 and 2.81nM, respectively). Comparing to Torin1, Torin2 displays enhanced inhibitory potency against PI 4-Kbeta (IC50 = 18.3nM) and PI 3-K (IC50 =4.68, 5.67, 8.58, 17.5, 24.5, and 28.1nM, respectively, against P110alpha/P85alpha, P110-gamma, hVPS34, P110delta/P85alpha, C2beta, C2alpha, respectively), while being more effective in inhibiting S6K1 Thr389 phosphorylation in MEF cultures (IC50 = 0.25nM vs 2nM, respectively, for Torin2 and Torin1) in vitro and displaying much improved oral bioavailability in mice (Cmax (ng/mL) /T1/2 (h) = 3968/0.72 and 223/0.79, respectively, for Torin2 and Torin1; 10/mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O, Primary Target: MTOR. US Biological Life Sciences. | Worldwide |
| mTOR Inhibitor XI, Torin1 (1- (4- (4-propionylpiperazin-1-yl) -3- (trifluoromethyl) phenyl) -9- (quinolin-3-yl) benzo[h][1, 6]naphthyridin-2 (1H) -one, DNA-PK Inhibitor VI, PI 3-K Inhibitor XVIII) | A cell-permeable pyridinonequinoline derivative that acts as a highly potent, ATP-competitive inhibibitor against mTOR and DNA-PK (IC50 = 4.32 and 6.34nM, respectively), while inhibiting PI 3-K only at much higher concentrations (IC50 =171 to 533nM). Effectively inhibits mTORC1-mediated S6K1 phosphorylation in MEF (IC50 = 2nM) in vitro, as well as mTORC2-mediated Akt and mTORC1-dependent S6 phosphorylations in murine lung and liver in vivo (up to 6h post single 20mg/kg i.p. dose). Despite its poor in vivo stability (T1/2 = 4.52h in mice; 10mg/kg i.p.), Torin1 is reported to completely suppress U87MG-derived tumor expansion in mice when administered via daily i.p. at a high dosage of 200mg/kg. Also reported to effectively inhibit cellular mTORC1 functionalities known to be rapamycin-resistant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MT(PEG)4 Methyl-PEG-Thiol Compound | MT(PEG)4 Methyl-PEG-Thiol Compound. | |
| MTPG | MTPG. Group: Biochemicals. Grades: Purified. CAS No. 169209-66-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| m-Trifluoromethoxybenzoic acid | m-Trifluoromethoxybenzoic acid. CAS No. 1014-81-9. Purity: 98%. Product ID: ACM1014819. Molecular formula: C8H5F3O3. Mole weight: 206.12. Alfa Chemistry - ISO 9001:32057 Certified. | |
| m-Trifluoromethylacetanilide | White crystals. Synonym: 3-Acetamidobenzotrifluoride. CAS No. 351-36-0. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 203.16. MP/BP: M.P. 101-102. Order No: FR-0903. | Frinton Laboratories |
| m-Trifluoromethylaniline | Liquid darkens in air, d20 1.29. Synonym: m-Aminobenzotrifluoride. CAS No. 98-16-8. Pack Sizes: Typically in stock: 250g. Mole weight: 161.13. MP/BP: B.P. 186-187. Order No: FR-0371. | Frinton Laboratories |
| m-Trifluoromethylphenol | Clear liquid, d20 1.33. Synonym: m-Hydroxybenzotrifluoride. CAS No. 98-17-9. Pack Sizes: Typically in stock: 50g. Mole weight: 162.11. MP/BP: B.P. 178-179. Order No: FR-1237. | Frinton Laboratories |
| mTRP-2 (180-188) | mTRP-2 (180-188) is a murine tyrosinase-related protein 2 (TRP-2) -derived peptide, corresponding to residues 180-188. TRP-2 (180-188) is identified as the major reactive epitope within TRP-2 recognized by anti-B16 CTLs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 219312-69-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1827. | |
| mTRP-2 (180-188) | mTRP-2 (180-188) is a murine tyrosinase-related protein 2 (TRP-2)-derived peptide, corresponding to residues 180-188. CAS No. 219312-69-3. Molecular formula: C61H78N10O14. Mole weight: 1175.33. | |
| MTSSL | Highly reactive, thiol-specific spin-label. Specific conformational probe of thiol site structure by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study. Used to label cysteine residues in proteins (site-directed labeling, SDS-labeling). Allows protein structure and protein dynamics determination as well as the study of protein-protein and protein-oligonucleotide interactions. Group: Biochemicals. Grades: Highly Purified. CAS No. 81213-52-7. Pack Sizes: 10mg, 50mg. Molecular Formula: C10H18NO3S2. US Biological Life Sciences. | Worldwide |
| MTT | MTT. Uses: For analytical and research use. Alternative Names: 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium Bromide; Thiazolyl Blue Tetrazolium Bromide. CAS No. 298-93-1. Molecular formula: C18H16BrN5S. Mole weight: 414.33. Purity: >97.0%(HPLC). Catalog: APB298931. | |
| Mtt-Lys(Fmoc)-OH | Mtt-Lys(Fmoc)-OH. Molecular formula: C41H40N2O4. Mole weight: 624.79. | |
| MTT (Thiazolyl blue tetrazolium bromide) | 5g Pack Size. Group: Stains & Indicators. Formula: C18H16BrN5S. CAS No. 298-93-1. Prepack ID 14706101-5g. Molecular Weight 414.32. See USA prepack pricing. | |
| MTT (Thiazolyl blue tetrazolium bromide) | 1g Pack Size. Group: Stains & Indicators. Formula: C18H16BrN5S. CAS No. 298-93-1. Prepack ID 14706101-1g. Molecular Weight 414.32. See USA prepack pricing. | |
| MTX115325 | MTX115325 (Example 1) is an orally active, brain-penetrating USP30 inhibitor (IC50=12 nM) with neuroprotective activity. MTX115325 increases ubiquitination (EC50=32 nM) of the mitochondrial outer membrane protein TOM20 (a USP30 substrate), increasing mitophagy. MTX115325 prevents dopaminergic neuron loss and preserves striatal dopamine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750895-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-160019. | |
| MTX-23 | MTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PROTAC AR-V7 degrader-2. CAS No. 2488296-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148771. | |
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