A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
NRX-1532 is a small molecule enhancer of β-catenin:β-TrCP interaction. Uses: Scientific research. Category: Signaling pathways. CAS No. 3083833-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144982.
NRX-252114
NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763260-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111836.
NRX-252262
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2438637-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111760.
NRX-2663
NRX-2663 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC50 of 22.9 μM and a Kd of 54.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763260-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141448.
NS
NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase.
NS 11021
NS 11021 is a potent and specific Ca2+-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 956014-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13103.
NS 11021
NS 11021. Group: Biochemicals. Grades: Purified. CAS No. 956014-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 1619
NS 1619. Group: Biochemicals. Grades: Purified. CAS No. 153587-01-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NS-1619
NS-1619 is an opener of large conductance Ca2+-activated K+ (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10?-?30?μM in several smooth muscles of blood vessels and other tissues[1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 153587-01-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12496.
NS1643
NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K+ channels with an EC50 of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 448895-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16916.
NS 1643
NS 1643. Group: Biochemicals. Alternative Names: 1, 3-Bis (2-hydroxy-5-trifluoromethylphenyl) urea; N, N'-bis[2-hydroxy-5- (trifluoromethyl) phenyl]urea. Grades: Highly Purified. CAS No. 448895-37-2. Pack Sizes: 10mg. Molecular Formula: C15H10F6N2O2S, Molecular Weight: 396.31. US Biological Life Sciences.
Worldwide
NS 1738
NS 1738. Group: Biochemicals. Grades: Purified. CAS No. 501684-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 19504
NS 19504. Group: Biochemicals. Grades: Purified. CAS No. 327062-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide
N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (S)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 151252-80-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences.
Worldwide
NS 2028
NS 2028. Group: Biochemicals. Grades: Purified. CAS No. 204326-43-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 257 HYDROCHLORIDE COMPETITIVE AMPA AN TA
NS 257 HYDROCHLORIDE COMPETITIVE AMPA AN TA. CAS No. 147750-87-6. Purity: 96%. Product ID: ACM147750876. Molecular formula: C13H16N4O4S. Mole weight: 324.35554;g/mol. IUPAC Name: 3-(hydroxyamino)-N,N,7-trimethyl-2-oxo-6,8-dihydropyrrolo[3,4-g]indole-5-sulfonamide. Alfa Chemistry - ISO 9001:32057 Certified.
NS2B/NS3-IN-2
NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3010940-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144612.
NS2B/NS3-IN-3 hydrochloride
NS2B/NS3-IN-3 hydrochlorideis an inhibitor of Flavivirus NS2B-NS3 protease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832876-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144644A.
NS2B/NS3-IN-4
NS2B/NS3-IN-4. Alternative Names: NS2B/NS3-IN-4;CHEMBL4865575;2910757-30-9;BDBM50572185;HY-144736;CS-0434400. CAS No. 2910757-30-9. Molecular formula: C15H11NO4. Mole weight: 269.25.
NS2B/NS3-IN-5
NS2B/NS3-IN-5. Alternative Names: NS2B/NS3-IN-5;CHEMBL4878316;BDBM50572174;HY-144740;CS-0434402;2910757-21-8. CAS No. 2910757-21-8. Molecular formula: C16H20ClN3S. Mole weight: 321.9.
NS2B/NS3-IN-8
NS2B/NS3-IN-8. Alternative Names: NS2B/NS3-IN-8;1021221-94-2;N-(5,7-dimethylthiazolo[4,5-b]pyridin-2-yl)benzofuran-2-carboxamide;N-{5,7-dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-yl}-1-benzofuran-2-carboxamide;N-(5,7-dimethyl-[1,3]thiazolo[4,5-b]pyridin-2-yl)-1-benzofuran-2-carboxamide;AKOS024476344;CCG-342126;HY-163318;CS-0999505;VU0505916-1;SR-01000917296;SR-01000917296-1;F2929-0095. CAS No. 1021221-94-2. Molecular formula: C17H13N3O2S. Mole weight: 323.37.
A useful disulfide cleavable linking reagent. Group: Biochemicals. Alternative Names: Boc-Aoa-NH-(CH2)2-S-S-Pyr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NS-304
NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Alternative Names: Selexipag; NS304; NS 304; ACT-293987; ACT293987; ACT 293987; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide. Grades: ≥95%. CAS No. 475086-01-2. Molecular formula: C26H32N4O4S. Mole weight: 496.6.
NS309
NS309 is a potent and selective activator of the Ca2+-activated SK/IK potassium channels, but displays no activity at BK channels[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18711-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15416.
NS 309
NS 309. Group: Biochemicals. Grades: Purified. CAS No. 18711-16-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS3623
NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 343630-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108586.
NS 3623
NS 3623. Group: Biochemicals. Alternative Names: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2- (2H-tetrazol-5-yl) phenyl]-N'-[3- (trifluoromethyl) phenyl]-urea. Grades: Highly Purified. CAS No. 343630-41-1. Pack Sizes: 10mg. Molecular Formula: C15H10BrF3N6O, Molecular Weight: 427.18. US Biological Life Sciences.
Worldwide
NS3694
NS3694, a diarylurea compound, is an apoptosome inhibitor. NS3694 inhibits apoptosome formation and caspase activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108356.
NS 3763
NS 3763. Group: Biochemicals. Grades: Purified. CAS No. 70553-45-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 398
NS 398. Group: Biochemicals. Grades: Purified. CAS No. 123653-11-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS-398
NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913.
NS-398 (NS398, NS 398)
NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences.
Worldwide
NS-5
NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32.
NS5806
NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-108588.
NS 5806
NS5806 is a KV4.3 channel activator. It can mediate the transient outward K+ current (Ito). Alternative Names: NS-5806; NS 5806; NS5806; N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea. Grades: ≥99% by HPLC. CAS No. 426834-69-7. Molecular formula: C16H8Br2F6N6O. Mole weight: 574.07.
NS 5806
NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS 6180
NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NS8593 hydrochloride
NS8593 hydrochloride is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca2+-dependently (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), and does not affect the Ca2+-activated K+ channels of intermediate and large conductance (hIK and hBK channels, respectively)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110105.
An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
NS 9283
NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
N-Salicylideneaniline
N-Salicylideneaniline. Group: Biochemicals. Alternative Names: N-Salicylalaniline. Grades: Highly Purified. CAS No. 779-84-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
N,S-Bis-Fmoc-Glutathione
N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149438-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-P4277.
NSC 109555
NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences.
Worldwide
NSC 109555 ditosylate
NSC 109555 ditosylate. Group: Biochemicals. Grades: Purified. CAS No. 66748-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC117079
NSC117079 is a novel PHLPP inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 500363-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19819.
NSC139021 (ERGi-USU) is a RIOK2 inhibitor with anticancer activity. RIOK2 can highly selectively inhibit the growth of ERG-positive cancer cells with IC50s of 30-400 nM against cell lines. RIOK2 also causes cell cycle arrest and apoptosis in glioblastoma via induction of Skp2 and Skp2-p27/p21-Cyclin E/CDK2-pRb signaling[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ERGi-USU. CAS No. 1147-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-112158.
NSC 146109 hydrochloride
NSC 146109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 59474-01-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NSC 15364
NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4550-72-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108937.
NSC15520
NSC15520 is a small molecular inhibitor of Replication Protein A (RPA). NSC15520 specifically recognizes the RPA N-terminal DNA binding domain (DBD), and blocks the interaction of RPA with p53 or RAD9. NSC15520 also inhibtis helix destabilization of a duplex DNA (dsDNA) oligonucleotide, involves in DNA replication, DNA repair, DNA recombination, and DNA damage response signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 730960-98-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138155.
NSC 185058
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39122-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125169.
NSC 185058
NSC 185058 is an inhibitor of ATG4B that inhibits ATG4B activity in vitro and in cells with no effect against MTOR and PtdIns3K. It inhibited autophagy and exhibited a negative impact on the development of Saos-2 osteosarcoma tumors in vivo. Alternative Names: N-(pyridin-2-yl)pyridine-2-carbothioamide. Grades: ≥98%. CAS No. 39122-38-8. Molecular formula: C11H9N3S. Mole weight: 215.3.
NSC 194308
NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90379-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153736.
NSC194598
NSC194598 is a p53 DNA-binding inhibitor with an IC50 value of 180 nM. NSC194598 inhibits p53 DNA binding and induction of target genesn when p53 is stabilized and activated by irradiation or chemotherapy. NSC194598 can interfere with transcriptional activation of mutated rearranged during transfection (RET) gene, induce apoptosis and G0/G1 phase arrest. NSC194598 can be used for the researches of acute radiation toxicity and medullary thyroid carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5358-76-9. Pack Sizes: 1 mg. Product ID: HY-156135.
NSC 23005 sodium
NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Alternative Names: NSC 23005 sodium; NSC23005 sodium; NSC-23005 sodium; 4-[(Cyclohexylamino)sulfonyl]benzoic acid sodium salt. Grades: ≥99% by HPLC. CAS No. 1796596-46-7. Molecular formula: C13H16NNaO4S. Mole weight: 305.33.
NSC 23005 Sodium Salt
NSC 23005 Sodium Salt is used to perpare sodium sodium cyclohexyl aminosulfonyl benzoate as p18 micromolecule inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1796596-46-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H16NNaO4S, Molecular Weight: 305.33. US Biological Life Sciences.
Worldwide
NSC232003
NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. Uses: Scientific research. Category: Signaling pathways. CAS No. 1905453-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-103236.
NSC 23766
NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment. Uses: Scientific research. Category: Signaling pathways. CAS No. 733767-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723.
NSC 23766 trihydrochloride
NSC 23766 is a Rac GTPase inhibitor that suppresses Rac GTPase activation by the Rac-specific GEFs. It shows an inhibitory activity in the influenza virus, as well as the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells. Alternative Names: NSC 23766 (trihydrochloride); NSC23766 (trihydrochloride); NSC-23766 (trihydrochloride); N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride. Grades: ≥98%. CAS No. 1177865-17-6. Molecular formula: C24H38Cl3N7. Mole weight: 530.967.
NSC 23766 trihydrochloride
NSC 23766 trihydrochloride is an inhibitor of Rac1 activation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177865-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723A.
NSC 23766 Trihydrochloride
NSC 23766 trihydrochloride is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA. Group: Inhibitors. CAS No. 1177865-17-6. Pack Sizes: 10mg. Product ID: S8031. Formula: C24H35N7.3ClH. Smiles: CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
NSC243928 mesylate
NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59988-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123885.
NSC 245214
NSC 245214 is a thienyl cycloalkanone that is part of the US National Cancer Institute small molecule repository. The biological activity of this compound has not been reported. Group: Biochemicals. Alternative Names: 2-(3,5-dinitro-2-thienyl)-cyclohexanone. Grades: Highly Purified. CAS No. 31554-45-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C10H10N2O5S, Form: Supplied as a crystalline. US Biological Life Sciences.
Worldwide
NSC260594
NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMH95. CAS No. 906718-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-112591.