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| Product | Description | |
|---|---|---|
| NSC 280449 | NSC 280449 is a derivative of Tromethamine (T892600); a compound that is widely used in biochemistry and molecular biology. In medicine, Tromethamine is used as an alternative to sodium bicarbonate in the treatment of metabolic acidosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60204-53-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H17NO3, Molecular Weight: 199.25. US Biological Life Sciences. |  Worldwide |
| NSC2805 | NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4371-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134417. |  |
| NSC305787 hydrochloride | NSC305787 hydrochloride is a small molecule inhibitor of PKC (IC50=8.3 μM) that directly inhibits ezrin protein as an approach to prevent tumor metastasis. Uses: A small molecule inhibitor of pkc. Alternative Names: NSC-305787 Hydrochloride; NSC 305787 Hydrochloride; NSC305787 Hydrochloride; NSC-305787 HCl; NSC 305787 HCl; NSC305787 HCl; [2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride;[2-(Adamantan-1-yl)-6,8-dichloro-4-quinolinyl](2-piperidinyl)methanol hydrochloride. Grades: ≥95%. CAS No. 53868-26-1. Molecular formula: C25H31Cl3N2O. Mole weight: 481.89. |  |
| NSC319726 | NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZMC1. CAS No. 71555-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18634. | |
| NSC 319726 | NSC 319726. Group: Biochemicals. Grades: Purified. CAS No. 71555-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 33994 | NSC 33994. Group: Biochemicals. Grades: Purified. CAS No. 82058-16-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC348884 | NSC348884 is a nucleophosmin (NPM) inhibitor, it disrupts oligomer formation and induces apoptosis, inhibits cell proliferation with IC50s of 1.7-4.0 μM in distinct cancer cell lines. NSC348884 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81624-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13915. | |
| NSC 3852 | NSC 3852. Group: Biochemicals. Grades: Purified. CAS No. 3565-26-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 405020 | NSC 405020. Group: Biochemicals. Grades: Purified. CAS No. 7497-7-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 405020 | NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7497-7-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-15827. | |
| NSC45586 sodium | NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the PP2C phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of ACAN/SOX9, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6300-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19820A. | |
| NSC47924 | NSC47924 is a laminin receptor (LR) inhibitor. NSC47924 affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. NSC47924 can be used for testing prion diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6638-24-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122066. | |
| NSC 521542 | NSC 521542 is an impurity in the synthesis of Dodecanedioic Acid-13C12 (D494532), labelled Dodecanedioic Acid. NSC 521542 is also used to prepare N- p- tosyl- tetrahydropyrrole. Alternative Names: 1,4-Butanediol Bis(4-methylbenzenesulfonate); 1,4-Butanediol Di-p-toluenesulfonate; 1,4-Bis(tosyloxy)butane; 1,4-Butanediol Ditosylate; 1,4-Di(4-methylphenylsulfonyloxy)butane; 1, 4- Butanediol 1,4-Bis(4-methylbenzenesulfona te). CAS No. 4724-56-5. Molecular formula: C18H22O6S2. Mole weight: 398.49. | |
| NSC61610 | NSC61610 disrupts hIL-18 binding to the ectromelia virus IL-18BP. NSC61610 inhibits hIL-18:ectvIL-18BP complex formation with an IC50 about 6?uM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500538-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-102019. | |
| NSC 617145 | NSC 617145. Group: Biochemicals. Grades: Purified. CAS No. 203115-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 617145 | NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 203115-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110185. | |
| NSC622608 | NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2593254-90-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147311. | |
| NSC624206 | NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13116-77-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103436. | |
| NSC 624206 | NSC 624206. Group: Biochemicals. Grades: Purified. CAS No. 13116-77-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 625987 | NSC 625987. Group: Biochemicals. Grades: Purified. CAS No. 141992-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 625987 | NSC625987 is a cyclin-dependent kinase 4 inhibitor with IC50 of 0.2 μM at cdk4 / cyclin D1. Alternative Names: NSC 625987; NSC-625987; NSC625987; Cdk4 Inhibitor II. 1,4-Dimethoxy-9(10H)-acridinethione. Grades: ≥98% by HPLC. CAS No. 141992-47-4. Molecular formula: C15H13NO2S. Mole weight: 271.33. | |
| NSC 625987 | NSC 625987 is a specific and high-affinity CDK4 inhibitor with an IC50 of 0.2 μM for CDK4:cyclin D1. NSC 625987 shows >500-fold selectivity for CDK4 over CDK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 141992-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103380. | |
| Nsc 632839 hydrochloride | Nsc 632839 hydrochloride. Alternative Names: NSC632839, NSC-632839, MLS002701647, AC1NS0DO, S4922,NSC632839,157654-67-6, 4-Piperidinone,5-bis[(4-methylphenyl)methylene]-, hydrochloride, (3E,5E)-3,5-bis[(4-methylphenyl)methylidene]piperidin-4-one hydrochloride, 3,5-BIS[(4-METHYLPHENYL)METHYLENE]-4-PIPERIDONE HYDROCHLORIDE, 157654-67-6. CAS No. 157654-67-6. Purity: >99 %. Product ID: ACM157654676. Molecular formula: C21H21NO.HCl. Mole weight: 339.86. IUPAC Name: (3E,5E)-3,5-bis[(4-methylphenyl)methylidene]piperidin-4-one;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| NSC 632839 hydrochloride | NSC 632839 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 157654-67-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC636819 | NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1618672-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-110154. | |
| NSC647889 | NSC647889 is an apoptosis and autophagy inducer. NSC647889 induces apoptosis, inhibits mTOR pathway and abrogates DNA synthesis. NSC647889 triggers LC3-positive vesicle formation, modulates AKT and 4EBP1 phosphorylation and shows heightened caspase-3 activation in multicellular spheroids. NSC647889 can be used for the research of solid cancer tumour, head-neck carcinoma, and colorectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1033931-92-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176761. | |
| NSC 663284 | NSC 663284. Group: Biochemicals. Grades: Purified. CAS No. 383907-43-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NSC 663284 | NSC 663284 (DA-3003-1) is a potent, cell-permeable, and irreversible Cdc25 dual specificity phosphatase inhibitor, has an IC50 for Cdc25B2 of 0.21 μM. NSC 663284 exhibits mixed competitive kinetics against Cdc25A, Cdc25B(2), and Cdc25C with Ki values of 29, 95, and 89 nM, respectively[1]. NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM)[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DA-3003-1. CAS No. 383907-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100034. | |
| NSC668036 | NSC668036 is a Dishevelled (Dvl) PDZ domain inhibitor with a Kd of 237 μM. NSC668036 blocks Wnt signaling by interrupting the Frizzled-Dvl interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 144678-63-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117666. | |
| NSC 66811 | NSC 66811. Group: Biochemicals. Grades: Purified. CAS No. 6964-62-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC668394 | NSC668394 is a potent ezrin (Thr567) phosphorylation inhibitor, with a Kd of 12.59 μM. NSC668394 inhibit ezrin T567 phosphorylation caused by PKC&Lota; primarily via their binding to ezrin. NSC668394 can be used to prevent tumor metastasis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 382605-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115492. | |
| NSC 687852 | NSC 687852. Group: Biochemicals. Grades: Purified. CAS No. 1009817-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC689857 | NSC689857 is a potent EGFR and SCFSKP2 inhibitor with an IC50 value of 36 μM for Skp2-Cks1. NSC689857 can inhibit p27 ubiquitylation (IC50=30 μM). NSC689857 has varied activity across cancer types, with more activity against leukemia cell lines than others[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 241127-79-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123578. | |
| NSC 693868 | NSC 693868. Group: Biochemicals. Grades: Purified. CAS No. 40254-90-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC697923 | Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate. NF-kB activation inhibitor. Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (Diffuse large B cell lymphoma) cells. Group: Biochemicals. Alternative Names: 2-[(4-Methylphenyl)sulfonyl]-5-nitro-Furan, 2-Nitro-5-tosylfuran. Grades: Highly Purified. CAS No. 343351-67-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H?NO?S. US Biological Life Sciences. | Worldwide |
| NSC697923 | NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 343351-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13811. | |
| NSC 697923 | NSC 697923. Group: Biochemicals. Grades: Purified. CAS No. 343351-67-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 74859 | NSC 74859 (S3I-201) is a selective Stat3 inhibitor with an IC50 of 86 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S3I-201. CAS No. 501919-59-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15146. | |
| NSC 74859 | NSC 74859. Group: Biochemicals. Grades: Purified. CAS No. 501919-59-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 74859 (S3I-201) | NSC 74859 (S3I-201) shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM in cell-free assays, and low activity towards STAT1 and STAT5. Group: Inhibitors. CAS No. 501919-59-1. Pack Sizes: 5mg. Product ID: S1155. Formula: C16H15NO7S. Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| NSC781406 | NSC781406 is a highly potent PI3K and mTOR inhibitor with an IC50 of 2 nM for PI3Kα. Uses: Scientific research. Category: Signaling pathways. CAS No. 1676893-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100470. | |
| NSC 87877 | NSC 87877. Group: Biochemicals. Alternative Names: 8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonic Acid. Grades: Highly Purified. CAS No. 56990-57-9. Pack Sizes: 100mg. Molecular Formula: C20H14N2O7S2, Molecular Weight: 458.46. US Biological Life Sciences. | Worldwide |
| NSC-87877 | NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56990-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18756. | |
| NSC 87877 sodium | NSC 87877 is a potent cell-permeable inhibitor of SHP-1/2 PTPs. It dose-dependently inhibits dual-specificity protein phosphatase 26 (DUSP26) which is involved in survival of anaplastic thyroid cancer (ATC) cells, suggesting that it has the potential for treating thyroid cancer. Alternative Names: Disodium 8-hydroxy-7-[(6-sulphonato-2-naphthyl)azo]quinoline-5-sulphonate. CAS No. 56932-43-5. Molecular formula: C19H13N3O7S2ยท2Na. Mole weight: 503.42. | |
| NSC 90469 | NSC 90469 (3,5-Diiodo-L-thyronine) is an orally active thyroid hormone derivative. NSC 90469 inhibits JNK phosphorylation and NF-κB acetylation, blocks SIRT1 protein expression, induces elevated PGC-1α levels, and stimulates COX activity. NSC 90469 enhances UCP1-mediated thermogenesis, increases hepatic Dio1 activity, inhibits TSH levels and hypothalamic-pituitary-thyroid axis function, enhances lipid metabolism, and regulates energy metabolism via the mitochondrial pathway. NSC 90469 prevents blood glucose reduction, reduces urinary albumin excretion, inhibits renal matrix expansion, decreases TGF-β1 expression, and reduces renal fibronectin and type ? collagen deposition. NSC 90469 also increases energy expenditure and prevents diet-induced overweight. NSC 90469 can be used in studies related to diabetic nephropathy, hypothyroidism, non-alcoholic fatty liver disease, and diet-induced obesity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3,5-Diiodo-L-thyronine. CAS No. 1041-01-6. Pack Sizes: 250 mg; 500 mg. Product ID: HY-114557. | |
| NSC 91800 | NSC 91800. Group: Biochemicals. Alternative Names: 1, 2, 3, 4, 5, 6, 7, 8, 10, 10, 11, 11-Dodecachloro-4, 4a, 4b, 5, 8, 8a, 9, 9a-octahydro-1, 4:5, 8-dimethano-1H-fluorene. Grades: Highly Purified. CAS No. 13560-91-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C15H6Cl12. US Biological Life Sciences. | Worldwide |
| NSC 95397 | NSC 95397. Group: Biochemicals. Grades: Purified. CAS No. 93718-83-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 95397 | NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B))[1]. NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 93718-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108543. | |
| Ns-D1 | Ns-D1 is an antimicrobial peptide found in seeds, Nigella sativa L. (Ranunculaceae). It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. It is a plant defensin containing four disulfide bridges. Alternative Names: Defensin D1. Grades: >85%. Molecular formula: C232H347N69O70S8. Mole weight: 5479.26. | |
| Ns-D2 | Ns-D2 is an antimicrobial peptide found in seeds, Nigella sativa L. (Ranunculaceae). It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. It is a plant defensin containing four disulfide bridges. Alternative Names: Defensin D2. Grades: >85%. Molecular formula: C233H351N69O70S8. Mole weight: 5495.31. | |
| NSD2-IN-1 | NSD2-IN-1 (compound 38) is a potent and high selective NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1) inhibitor, with an IC50 of 0.11 μM. NSD2-IN-1 can bind to NSD2-PWWP1 and then affect the expression of genes regulated by NSD2. NSD2-IN-1 induces apoptosis and cell cycle arrest[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2797183-37-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147914. | |
| N,S-Diacetyl-L-cysteine | A double-prodrugs of L-cysteine. Group: Biochemicals. Alternative Names: N-Acetylcysteine. Grades: Highly Purified. CAS No. 18725-37-6. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| NSD-IN-2 | NSD-IN-2 is a potent and irreversible NSD inhibitor with inhibitory activity towards members of the NSD family (NSD1/2/3). NSD-IN-2 can be used in research of acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2351225-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134086. | |
| N,S-dioctyl-(D)-penicillamine | N,S-dioctyl-(D)-penicillamine. Alternative Names: D-Valine, N-octyl-3-(octylthio)-; N-Octyl-3-(octylsulfanyl)-D-valine. CAS No. 140939-18-0. Molecular formula: C21H43NO2S. Mole weight: 373.63. | |
| N,S-di-Z-L-cysteine | N,S-di-Z-L-cysteine. Group: Biochemicals. Alternative Names: Z-L-Cys(Z)-OH. Grades: Highly Purified. CAS No. 57912-35-3. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| N,S-di-Z-L-cysteine | N,S-di-Z-L-cysteine. Alternative Names: Z-L-Cys(Z)-OH; N,S-DI-Z-L-CYSTEINE; Cbz-Cys(Cbz)-OH; N,S-Bis-benzyloxycarbonyl-L-cystein; N-[(phenylmethoxy)carbonyl]-L-cysteine; N-(Phenylmethoxycarbonyl)-S-(phenylmethyloxycarbonyl)-L-cysteine. Grades: ≥ 98% (HPLC). CAS No. 57912-35-3. Molecular formula: C19H19NO6S. Mole weight: 389.40. | |
| N,S-di-Z-L-cysteine 98+% (HPLC) | N,S-di-Z-L-cysteine 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| N-sec-Butyl(trimethylsilyl)amine | N-sec-Butyl(trimethylsilyl)amine. Uses: For analytical and research use. CAS No. 17425-82-0. Mole weight: 145.32. Catalog: AP17425820. |  |
| NSI-189 | NSI-189 is an experimental drug being studied by Neuralstem, Inc. Research into NSI-189 has been funded by the Defense Advanced Research Projects Agency (DARPA) and the National Institutes of Health (NIH) for the treatment of major depressive disorder. NSI-189 successfully completed a phase 1 clinical trial in 2011 where it was administered to 41 healthy volunteers. A phase 1b clinical trial for treating major depressive disorder in 24 patients started in 2012 and completed in July 2014. The study suggests that there were improvements in the patients' condition when the doses were 40/80 mg per day, but no significant improvements were seen for a higher dosage of 120 mg/day. Neuralstem intends to pursue further clinical trials for a variety of neurological conditions, including major depressive disorder, traumatic brain injury, Alzheimer's disease, post-traumatic stress disorder, stroke, and natural cognitive and memory decline in aging. Uses: For research used only. Alternative Names: NSI-189; NSI 189; NSI189. Grades: 98%. CAS No. 1270138-40-3. Molecular formula: C22H30N4O. Mole weight: 366.5. | |
| N-SMP | N-SMP is a potent synthetic compound known for its efficacy against various neurological disorders. As a powerful inhibitor, this compound specifically targets key enzymes involved in the progression of these debilitating diseases. In addition, N-SMP is also widely used as a linker for antibody-drug conjugation. Alternative Names: 1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione; N-(α-Maleimidoacetoxy)succimide; AMAS; N-Succinimidyl maleimidoacetate; Maleimidoacetic Acid N-Succinimidyl Ester; N-(alpha-Maleimidoacetoxy)succinimide; a-Maleimidoacetic acid-NHS. Grades: 95%. CAS No. 55750-61-3. Molecular formula: C10H8N2O6. Mole weight: 252.18. | |
| Ns-NH-Et-OtBu | Ns-NH-Et-OtBu. Alternative Names: N-[2-[(2-Methylpropan-2-yl)oxy]ethyl]-2-nitrobenzenesulfonamide. CAS No. 887210-49-3. Molecular formula: C12H18N2O5S. Mole weight: 302.35. | |
| N-(S-Nitroso-N-acetyl-D,L-penicillamine)-2-amino-2-deoxy-1,3,4,6-tetra-O-acetyl-b-D-glucopyranose | N-(S-Nitroso-N-acetyl-D,L-penicillamine)-2-amino-2-deoxy-1,3,4,6-tetra-O-acetyl-b-D-glucopyranose, commonly referred to as NAPD, represents a remarkable and influential compound extensively employed in the field of biomedicine for investigating and addressing a myriad of diseases. Prominently, this extraordinary product has proven immensely advantageous in scientific exploration concerning cancer, inflammation, and cardiovascular disorders, demonstrating its vital role in the advancement of innovative and cutting-edge therapeutic interventions. Alternative Names: 2-[[(2S)-2-(Acetylamino)-3-methyl-3-(nitrosothio)-1-oxobutyl]amino]-2-deoxy-b-D-glucopyranose 1,3,4,6-tetraacetate; RIG200. CAS No. 202656-49-3. Molecular formula: C21H31N3O12S. Mole weight: 549.55. | |
| NSP-DMAE-ADH | The terminal of its molecular structure contains acylhydrazide group, which is easy to label proteins, antibodies or nucleic acids containing aldehyde, carbonyl or ketone groups. Alternative Names: 3-(9-((4-(2-(6-hydrazineyl-6-oxohexanoyl)hydrazine-1-carbonyl)-2,6-dimethylphenoxy)carbonyl)acridin-10-ium-10-yl)propane-1-sulfonate. Grades: ≥95%. Molecular formula: C32H35N5O8S. Mole weight: 649.71. | |
| NSP-DMAE-HEG-Glu-NHS | It belongs to the group of acridine chemiluminescent markers. Alternative Names: Acridinium, 9-[[4-[[[1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,5-dioxo-9,12,15,18,21-pentaoxa-6-azatricos-23-yl]amino]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)-, inner salt. Grades: ≥90%. CAS No. 1253933-74-2. Molecular formula: C47H58N4O16S. Mole weight: 967.05. | |
| NSP-DMAE-NHS | NSP-DMAE-NHS is an acridinium ester chemiluminescent reagent containing N-sulfopropyl groups. It is useful in the clinical diagnostic industry especially in automated immunochemical analyzers such as Siemens Healthcare Diagnostics' ADVIA Centaur systems. Alternative Names: 2',6'-Dimethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS Ester; 2',6'-Dimethyl-4'-(N-succinimidyloxycarbonyl) phenyl-10-sulfopropylacridinium-9-carboxylate; 9-[[4-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)acridinium Inner Salt. Grades: 95%. CAS No. 194357-64-7. Molecular formula: C30H26N2O9S. Mole weight: 590.60. | |
| NSP-DMAE-NHS | NSP-DMAE-NHS is an acridinium ester-based signal amplifier that can act as a luminescent probe to effectively improve the detection performance of biosensors. NSP-DMAE-NHS preserves the biochemical activity of biomolecules during the conjugation process. NSP-DMAE-NHS has been successfully applied to label mouse anti-human PI3 monoclonal antibodies for chemiluminescent immunoassays, as well as for pre-competitive chemiluminescent immunochromatographic detection of TP53 fusion proteins. NSP-DMAE-NHS can be used in detection studies of cancer and related biomarkers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 194357-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D0892. | |
| NSP-SA-NHS | It is a direct chemiluminescent reagent, used to mark proteins, antigens, antibodies, nucleic acids (DNA, RNA), etc. Alternative Names: 3-[9-(((3-(N-succinimidyloxycarboxypropyl)[4-methxylphenyl]sulfonyl)amine)carboxyl]-10-acridiniumyl)-1-propanesulfonate; 3-(9-((4-((2,5-Dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)(tosyl)carbamoyl)acridin-10-ium-10-yl)propane-1-sulfonate; 9-[[[4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl][(4-methylphenyl)sulfonyl]amino]carbonyl]-10-(3-sulfopropyl)-acridinium inner salt. Grades: ≥95%. CAS No. 199293-83-9. Molecular formula: C32H31N3O10S2. Mole weight: 681.73. | |
| NSP-SA-NHS | NSP-SA-NHS is an acridinium ester that can be used for chemiluminescent immunoassay. A rapid and sensitive chemiluminescent immunoassay of Bisphenol A (BPA) with NSP-SA-NHS-labeled has been developed[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199293-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0893. | |
| NSP-SA-N-Mal | The terminal of acridine NSP-SA-Nen-Mal has maleimide functional group, which can label proteins, antibodies or nucleic acids containing sulfhydryl group. Alternative Names: 3-(9-((4-((2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)amino)-4-oxobutyl)(tosyl)carbamoyl)acridin-10-ium-10-yl)propane-1-sulfonate. Grades: 97%. Molecular formula: C34H34N4O9S2. Mole weight: 706.78. | |
| NST-628 | NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3002056-30-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-158115. | |
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