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| Product | Description | |
|---|---|---|
| NS 11021 | NS 11021. Group: Biochemicals. Grades: Purified. CAS No. 956014-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NS 1619 | NS 1619. Group: Biochemicals. Grades: Purified. CAS No. 153587-01-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS-1619 | NS-1619 is an opener of large conductance Ca2+-activated K+ (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10?-?30?μM in several smooth muscles of blood vessels and other tissues[1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 153587-01-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12496. |  |
| NS1643 | NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K+ channels with an EC50 of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 448895-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16916. | |
| NS 1643 | NS 1643. Group: Biochemicals. Alternative Names: 1, 3-Bis (2-hydroxy-5-trifluoromethylphenyl) urea; N, N'-bis[2-hydroxy-5- (trifluoromethyl) phenyl]urea. Grades: Highly Purified. CAS No. 448895-37-2. Pack Sizes: 10mg. Molecular Formula: C15H10F6N2O2S, Molecular Weight: 396.31. US Biological Life Sciences. | Worldwide |
| NS 1738 | NS 1738. Group: Biochemicals. Grades: Purified. CAS No. 501684-93-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS1738 (1- (5-chloro-2-hydroxyphenyl) -3- (2-chloro-5- (trifluoromethyl) phenyl) urea, a7 nAChR Positive Allosteric Modulator, NS1738, NS 1738, NS-1738) | A biarylurea derivative that acts as a selective positive allosteric modulator selective for alpha7 nicotinic acetylcholine receptors (alpha7 nAChR) without substantial activity for alpha4beta2, alpha3beta3 and alpha1-containing receptors. Exhibits cognitive enhancing effects in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 501684-93-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 19504 | NS 19504. Group: Biochemicals. Grades: Purified. CAS No. 327062-46-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| N-[(S)-1-Carbethoxybutyl]-(S)-alanine | Perindopril intermediate. Group: Biochemicals. Alternative Names: (S)-N-(1-Carboxyethyl)-L-norvaline 1-Ethyl Ester; N-((S)-Ethoxycarbonyl-1-butyl)-(S)-alanine. Grades: Highly Purified. CAS No. 82834-12-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide | N-[(S)-(-)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (S)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 151252-80-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences. | Worldwide |
| NS 2028 | NS 2028. Group: Biochemicals. Grades: Purified. CAS No. 204326-43-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 257 HYDROCHLORIDE COMPETITIVE AMPA AN TA | NS 257 HYDROCHLORIDE COMPETITIVE AMPA AN TA. CAS No. 147750-87-6. Purity: 96%. Product ID: ACM147750876. Molecular formula: C13H16N4O4S. Mole weight: 324.35554;g/mol. IUPAC Name: 3-(hydroxyamino)-N,N,7-trimethyl-2-oxo-6,8-dihydropyrrolo[3,4-g]indole-5-sulfonamide. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| NS2B/NS3-IN-2 | NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3010940-08-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144612. | |
| NS2B/NS3-IN-3 hydrochloride | NS2B/NS3-IN-3 hydrochlorideis an inhibitor of Flavivirus NS2B-NS3 protease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832876-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144644A. | |
| NS2B/NS3-IN-8 | NS2B/NS3-IN-8 (compound SM7) is a Zika virus NS2B-NS3 protease inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1021221-94-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163318. | |
| N(S)-(2-(Diphenylphosphino)-6-methylphenyl)-N-methyladamantan-1-amine | N(S)-(2-(Diphenylphosphino)-6-methylphenyl)-N-methyladamantan-1-amine. CAS No. 1333903-45-9. Purity: 98%. Product ID: ACM1333903459-1. Molecular formula: C30H34NP. Mole weight: 439.57. Alfa Chemistry - ISO 9001:32057 Certified. | |
| N- [S- (2-Pyridylthio) cysteaminyl] ethylenediamine-N, N, N', N'-tetraacetic Acid, Monoamide, Technical grade 90% | A useful ligand for incorporation of EDTA-metal complexes into proteins particularly for investigating orientation of DNA binding proteins. Group: Biochemicals. Grades: Purified. CAS No. 143541-95-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide | N-[S-(2-Pyridylthioethyl)-t-boc-aminooxyacetamide. Group: Biochemicals. Alternative Names: Boc-aoa-NH-(CH2)2-S-S-pyr. Grades: Highly Purified. CAS No. 887407-46-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4S2. US Biological Life Sciences. | Worldwide |
| N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide (Boc-Aoa-NH-(CH2)2-S-S-Pyr) | A useful disulfide cleavable linking reagent. Group: Biochemicals. Alternative Names: Boc-Aoa-NH-(CH2)2-S-S-Pyr. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS309 | NS309 is a potent and selective activator of the Ca2+-activated SK/IK potassium channels, but displays no activity at BK channels[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18711-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15416. | |
| NS 309 | NS 309. Group: Biochemicals. Grades: Purified. CAS No. 18711-16-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS3623 | NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. NS3623 activates the IKr and Ito currents and has antiarrhythmic effect. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 343630-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108586. | |
| NS 3623 | NS 3623. Group: Biochemicals. Alternative Names: 1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea; N-[4-Bromo-2- (2H-tetrazol-5-yl) phenyl]-N'-[3- (trifluoromethyl) phenyl]-urea. Grades: Highly Purified. CAS No. 343630-41-1. Pack Sizes: 10mg. Molecular Formula: C15H10BrF3N6O, Molecular Weight: 427.18. US Biological Life Sciences. | Worldwide |
| NS3694 | NS3694, a diarylurea compound, is an apoptosome inhibitor. NS3694 inhibits apoptosome formation and caspase activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108356. | |
| NS 3763 | NS 3763. Group: Biochemicals. Grades: Purified. CAS No. 70553-45-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 398 | NS 398. Group: Biochemicals. Grades: Purified. CAS No. 123653-11-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS-398 | NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913. | |
| NS-398 (NS398, NS 398) | NS-398 (NS398, NS 398). Group: Biochemicals. Alternative Names: N- (2-cyclohexyloxy-4-nitrophenyl) methanesulfonamide. Grades: Highly Purified. CAS No. 123653-11-2. Pack Sizes: 50mg. Molecular Formula: C13 H18 N2O5, Molecular Weight: 314.4. US Biological Life Sciences. | Worldwide |
| NS-5 | NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32. |  |
| NS5806 | NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 426834-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-108588. | |
| NS 5806 | NS 5806. Group: Biochemicals. Grades: Purified. CAS No. 426834-69-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 6180 | NS 6180. Group: Biochemicals. Grades: Purified. CAS No. 353262-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS8593 hydrochloride | NS8593 hydrochloride is a potent and selective small conductance Ca2+-activated K+ channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3-mediated currents with a Kd value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca2+-dependently (Kds of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca2+), and does not affect the Ca2+-activated K+ channels of intermediate and large conductance (hIK and hBK channels, respectively)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110105. | |
| NS8593 ((R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine) | An aminobenzimidazole derivative that selectively and reversibly blocks small conductance Ca2+-activated K+ channels (SK1-3; =420nM, 600nM, and 730nM for SK1, SK2, SK3, respectively) in a Ca2+-dependent manner. It mediates channel gating by interacting with gating structures deep within the inner pore vestibule where Ser507 and Ala532 are deemed to be important for inhibition. Interacts at a site that is distinct from the apamin binding site in SK channels. Can access high-affinity binding sites from both the inside and outside of the cell membrane. Does not affect QT intervals, but prolongs the atrial effective refractive period and prevents acetylcholine-induced atrial fibrillations in ex vivo and in vivo models. Also shown to reversibly block TRPM7 channel (IC50=1.6mM) in smooth muscle cells, primary podocytes, HEK293 cells expressing TRPM7, and ventricular myocytes in a Mg2+-dependent manner and blocks the motility of cells in culture. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NS 9283 | NS 9283. Group: Biochemicals. Grades: Purified. CAS No. 913830-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| N-Salicylideneaniline | N-Salicylideneaniline. Group: Biochemicals. Alternative Names: N-Salicylalaniline. Grades: Highly Purified. CAS No. 779-84-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| N,S-Bis-Fmoc-Glutathione | N,S-Bis-Fmoc-Glutathione is a potent glyoxalase II inhibitor with a Ki value of 0.75 μM and an IC50 of 2.5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 149438-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-P4277. | |
| NSC 109555 | NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences. | Worldwide |
| NSC 109555 ditosylate | NSC 109555 ditosylate. Group: Biochemicals. Grades: Purified. CAS No. 66748-43-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC117079 | NSC117079 is a novel PHLPP inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 500363-63-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19819. | |
| NSC125066 | NSC125066 Inhibitor. Uses: Scientific use. Product Category: T6116. CAS No. 9041-93-4. |  |
| NSC 13138 (Standard) | NSC 13138 is an endogenous metabolite. Uses: Scientific research. Category: Signaling pathways. CAS No. 486-74-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-Y0057R. | |
| NSC139021 | NSC139021 (ERGi-USU) is a RIOK2 inhibitor with anticancer activity. RIOK2 can highly selectively inhibit the growth of ERG-positive cancer cells with IC50s of 30-400 nM against cell lines. RIOK2 also causes cell cycle arrest and apoptosis in glioblastoma via induction of Skp2 and Skp2-p27/p21-Cyclin E/CDK2-pRb signaling[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ERGi-USU. CAS No. 1147-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg. Product ID: HY-112158. | |
| NSC 146109 hydrochloride | NSC 146109 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 59474-01-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 15364 | NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4550-72-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108937. | |
| NSC15520 | NSC15520 is a small molecular inhibitor of Replication Protein A (RPA). NSC15520 specifically recognizes the RPA N-terminal DNA binding domain (DBD), and blocks the interaction of RPA with p53 or RAD9. NSC15520 also inhibtis helix destabilization of a duplex DNA (dsDNA) oligonucleotide, involves in DNA replication, DNA repair, DNA recombination, and DNA damage response signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 730960-98-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138155. | |
| NSC 177223 | NSC 177223. Group: Biochemicals. Alternative Names: 4-Amino-5,8-dihydro-5-oxo-8- β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; API-1. Grades: Highly Purified. CAS No. 36707-00-3. Pack Sizes: 5mg. Molecular Formula: C13H15N5O6, Molecular Weight: 337.29. US Biological Life Sciences. | Worldwide |
| NSC 185058 | NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. Inhibition of ATG4B using NSC 185058 markedly attenuates autophagic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39122-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125169. | |
| NSC 194308 | NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 90379-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153736. | |
| NSC194598 | NSC194598 is a p53 DNA-binding inhibitor with an IC50 value of 180 nM. NSC194598 inhibits p53 DNA binding and induction of target genesn when p53 is stabilized and activated by irradiation or chemotherapy. NSC194598 can interfere with transcriptional activation of mutated rearranged during transfection (RET) gene, induce apoptosis and G0/G1 phase arrest. NSC194598 can be used for the researches of acute radiation toxicity and medullary thyroid carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5358-76-9. Pack Sizes: 1 mg. Product ID: HY-156135. | |
| NSC 23005 Sodium Salt | NSC 23005 Sodium Salt is used to perpare sodium sodium cyclohexyl aminosulfonyl benzoate as p18 micromolecule inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1796596-46-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C13H16NNaO4S, Molecular Weight: 305.33. US Biological Life Sciences. | Worldwide |
| NSC232003 | NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. Uses: Scientific research. Category: Signaling pathways. CAS No. 1905453-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-103236. | |
| NSC 23766 | NSC 23766 is a cell-permeable, reversible and specific inhibitor of Rac GTPase, used for cancer treatment. Uses: Scientific research. Category: Signaling pathways. CAS No. 733767-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723. | |
| NSC 23766 trihydrochloride | NSC 23766 trihydrochloride is an inhibitor of Rac1 activation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177865-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15723A. | |
| NSC 23766 Trihydrochloride | NSC 23766 trihydrochloride is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of ~50 μM in a cell-free assay; does not inhibit the closely related targets, Cdc42 or RhoA. Group: Inhibitors. CAS No. 1177865-17-6. Pack Sizes: 10mg. Product ID: S8031. Formula: C24H35N7.3ClH. Smiles: CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| NSC243928 mesylate | NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59988-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123885. | |
| NSC 245214 | NSC 245214 is a thienyl cycloalkanone that is part of the US National Cancer Institute small molecule repository. The biological activity of this compound has not been reported. Group: Biochemicals. Alternative Names: 2-(3,5-dinitro-2-thienyl)-cyclohexanone. Grades: Highly Purified. CAS No. 31554-45-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C10H10N2O5S, Form: Supplied as a crystalline. US Biological Life Sciences. | Worldwide |
| NSC260594 | NSC260594 induces Apoptosis. NSC260594 binds the shallow groove of the Mcl-1 protein, and inhibits Mcl-1 expression through down-regulation of Wnt signaling proteins. NSC260594 can also recognize G9-G10-A11-G12 RNA tetraloop of HIV and prevent the binding of the Gag protein within the 5-UTR. NSC260594 inhibits tumor growth, and can be used for research of Triple-negative breast cancers (TNBCs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMH95. CAS No. 906718-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-112591. | |
| NSC-26326 | NSC-26326 Inhibitor. Uses: Scientific use. Product Category: T6407. CAS No. 4707-32-8. | |
| NSC 280449 | NSC 280449 is a derivative of Tromethamine (T892600); a compound that is widely used in biochemistry and molecular biology. In medicine, Tromethamine is used as an alternative to sodium bicarbonate in the treatment of metabolic acidosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60204-53-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H17NO3, Molecular Weight: 199.25. US Biological Life Sciences. | Worldwide |
| NSC2805 | NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4371-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134417. | |
| NSC319726 | NSC319726 (ZMC1) is a mutant p53R175 reactivator; inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM); shows no inhibition for p53 wild-type cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZMC1. CAS No. 71555-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18634. | |
| NSC 319726 | NSC 319726. Group: Biochemicals. Grades: Purified. CAS No. 71555-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 33994 | NSC 33994. Group: Biochemicals. Grades: Purified. CAS No. 82058-16-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC-33994 | NSC-33994 is novel inhibitor of JAK2 tyrosine kinase (Janus kinase 2 ). Janus kinase 2 (JAK2) plays a crucial role in the pathomechanism of myeloproliferative disorders and hematological malignancies. Group: Biochemicals. Alternative Names: 4, 4'-[ (1E) -1, 2-Diethyl-1, 2-ethenediyl]bis[2-[ (diethylamino) methyl]phenol; (E) -4, 4'- (1, 2-Diethyl-1, 2-ethenediyl) bis[2-[ (diethylamino) methyl]phenol. Grades: Highly Purified. CAS No. 82058-16-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| NSC348884 | NSC348884 is a nucleophosmin (NPM) inhibitor, it disrupts oligomer formation and induces apoptosis, inhibits cell proliferation with IC50s of 1.7-4.0 μM in distinct cancer cell lines. NSC348884 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81624-55-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13915. | |
| NSC 3852 | NSC 3852. Group: Biochemicals. Grades: Purified. CAS No. 3565-26-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 405020 | NSC 405020. Group: Biochemicals. Grades: Purified. CAS No. 7497-7-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NSC 405020 | NSC 405020 is a specific MMP14 inhibitor. NSC 405020 can directly interact with the hemopexin domain of MMP14. NSC 405020 reduces the expression of full length and active cleaved Notch3 (NICD3). NSC 405020 can be used to research vestibular schwannoma, hemostasis and thrombosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7497-7-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-15827. | |
| NSC45586 sodium | NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the PP2C phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of ACAN/SOX9, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6300-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19820A. | |
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