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| Product | Description | |
|---|---|---|
| N-Propylurea | White crystalline. CAS No. 627-06-5. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 102.14. MP/BP: M.P. 106-108. Order No: FR-1259. |  Frinton Laboratories |
| NPS-2143 | NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-262470A. CAS No. 284035-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10007. |  |
| NPS 2143 hydrochloride | NPS 2143 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 324523-20-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NPS-2143 hydrochloride | NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-262470A hydrochloride. CAS No. 324523-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10171. | |
| NPS 2390 | NPS 2390. Group: Biochemicals. Grades: Purified. CAS No. 226878-01-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NPS ALX Compound 4a dihydrochloride | NPS ALX Compound 4a dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 299433-10-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NpThio1 | NpThio1 is an antimicrobial peptide found in Nicotiana paniculata, and has antifungal activity. Synonyms: NpThio1 (Plant defensin). Molecular formula: C229H376N66O65S8. Mole weight: 5350.44. |  |
| N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride | N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride. Group: Biochemicals. Alternative Names: Tosyl-L-phenylalanyl Chloride. Grades: Highly Purified. CAS No. 29739-88-6. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| N-(p-Toluenesulfonyl)urea | N-(p-Toluenesulfonyl)urea. Group: Biochemicals. Alternative Names: N-(p-Tolylsulfonyl)urea; Tosylurea; (p-Toluenesulfonyl)urea; (p-Tolylsulfonyl)urea; H 16650; (p-Tolylsulfonyl)urea; N- (Aminocarbonyl) -4-methyl Benzene sulfonamide. Grades: Highly Purified. CAS No. 1694-06-0. Pack Sizes: 5g. Molecular Formula: C8H10N2O3S, Molecular Weight: 214.24. US Biological Life Sciences. | Worldwide |
| N-(p-Tolyl)-1-naphthylamine | N-(p-Tolyl)-1-naphthylamine. CAS No. 634-43-5. Molecular formula: C17H15N. Mole weight: 233.31g/mol. IUPAC Name: N-(4-methylphenyl)naphthalen-1-amine. SMILES: CC1=CC=C(C=C1)NC2=CC=CC3=CC=CC=C32. InChI: InChI=1S/C17H15N/c1-13-9-11-15(12-10-13)18-17-8-4-6-14-5-2-3-7-16(14)17/h2-12,18H,1H3. |  |
| N-(p-Tolyl)-2-naphthylamine | N-(p-Tolyl)-2-naphthylamine. Alternative Names: 2-(P-TOLUIDINO)NAPHTHALENE;N-(P-TOLYL)-2-NAPHTHYLAMINE;(4-methylphenyl)-(2-naphthyl)amine;N-(4-methylphenyl)naphthalen-2-amine. CAS No. 644-16-6. Molecular formula: C17H15N. Mole weight: 233.31g/mol. IUPAC Name: N-(4-methylphenyl)naphthalen-2-amine. SMILES: CC1=CC=C(C=C1)NC2=CC3=CC=CC=C3C=C2. InChI: InChI=1S/C17H15N/c1-13-6-9-16(10-7-13)18-17-11-8-14-4-2-3-5-15(14)12-17/h2-12,18H,1H3. | |
| N-p-Tolyl-guanidine | N-p-Tolyl-guanidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 54015-04-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N-p-Tolyl-guanidine 99+% | N-p-Tolyl-guanidine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| N-(p-Tolyl)thiourea ≥97% (HPLC) | N-(p-Tolyl)thiourea ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 622-52-6. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| N-(p-Tosyl)carbamic Acid Methyl Ester | N-(p-Tosyl)carbamic Acid Methyl Ester is a degradation product of Gliclazide. Group: Biochemicals. Alternative Names: (p-Tolylsulfonyl)carbamic Acid Methyl Ester; [ (4-Methylphenyl) sulfonyl]carbamic Acid Methyl Ester; Methyl N- (p-toluenesulfonyl) carbamate; Methyl N-(p-Tosyl)carbamate. Grades: Highly Purified. CAS No. 14437-03-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride | N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride. Uses: For analytical and research use. CAS No. 117961-27-0. Mole weight: 676.18. Catalog: AP117961270. |  |
| N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride | N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride. Synonyms: Tos-Gly-Pro-Arg-AMC HCl; N-[(4-methylphenyl)sulfonyl]glycyl-N-{(2S)-5-[(diaminomethylidene)amino]-2-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]pentanoyl}-L-prolinamide. CAS No. 117961-27-0. Molecular formula: C30H38ClN7O7S. Mole weight: 676.18. | |
| N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt | N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Synonyms: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. Grade: ≥98% by TLC. CAS No. 88793-79-7. Molecular formula: C28H38N6O9S. Mole weight: 634.70. | |
| N-p-trans-Coumaroyltyramine | N-p-Coumaroyltyramine comes from the herbs of Exochorda racemosa. Synonyms: (2E)-3-(4-Hydroxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide. Grade: 0.98. CAS No. 36417-86-4. Molecular formula: C17H17NO3. Mole weight: 283.3. | |
| NPY 5RA972 | NPY 5RA972. Group: Biochemicals. Grades: Purified. CAS No. 439861-56-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| N-Pyrazinylcarbonyl-L-phenylalanine | N-Pyrazinylcarbonyl-L-phenylalanine. Group: Biochemicals. Alternative Names: N-(2-pyrazinylcarbonyl)-L-phenylalanine. Grades: Highly Purified. CAS No. 114457-94-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C14H13N3O3. US Biological Life Sciences. | Worldwide |
| N-Pyrazinylcarbonyl-L-phenylalanine methyl ester | Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates. Group: Biochemicals. Alternative Names: N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester; 3-Phenyl-2-[ (pyrazine-2-carbonyl) amino]propionic Acid Methyl Ester. Grades: Highly Purified. CAS No. 73058-37-4. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??N?O?, Molecular Weight: 285.3. US Biological Life Sciences. | Worldwide |
| N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester | N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester. Alternative Names: Bortezomib Impurity R. CAS No. 73058-37-4. Purity: 95%. Product ID: ACM73058374. Molecular formula: C15H15N3O3. Mole weight: 285.29. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| N-Pyrazinyl carbonyl phenyl alanine (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid) | N-Pyrazinyl carbonyl phenyl alanine (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid). Group: Biochemicals. Alternative Names: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-Pyrazinyl carbonyl phenyl alanine-d8 | N-Pyrazinyl carbonyl phenyl alanine-d8. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Pyrazinyl carbonyl phenyl alanine Methyl Ester (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester) | N-Pyrazinyl carbonyl phenyl alanine Methyl Ester (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester). Group: Biochemicals. Alternative Names: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-(pyridin-3-ylmethyl)cyclopropanamine | N-(pyridin-3-ylmethyl)cyclopropanamine. Alternative Names: Cyclopropyl-pyridin-3-ylmethyl-amine, N-(pyridin-3-ylmethyl)cyclopropanamine, 183609-18-9, cyclopropyl(3-pyridylmethyl)amine, AC1LMMOT, BAS 05541966, ACMC-209ekt, SureCN664734, CTK5J6680, MolPort-000-938-918, BB_SC-4265, HMS1704C04, Cyclopropyl-pyridin-3-ylmethylamine, AC1Q2910, ANW-23163, BBL007852, SBB085360, STK511388, AKOS000264143, AG-B-20157. CAS No. 183609-18-9. Purity: 96%. Product ID: ACM183609189. Molecular formula: C9H12N2. Mole weight: 148.20. IUPAC Name: N-(pyridin-3-ylmethyl)cyclopropanamine. Alfa Chemistry - ISO 9001:32057 Certified. | |
| N- (Pyridin-4-Ylmethyl) Methanesulfonamide | N- (Pyridin-4-Ylmethyl) Methanesulfonamide. Group: Biochemicals. Grades: Reagent Grade. CAS No. 349404-63-3. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| N-Pyrrolo-2'-deoxycytidine | N-Pyrrolo-2'-deoxycytidine. Group: Biochemicals. Alternative Names: 6-Methyl-3- (b-D-2-deoxyribofuranosyl) pyrrolo[2, 3-d]pyrimidin-2-one. Grades: Highly Purified. CAS No. 382137-74-8. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C12H15N3O4. US Biological Life Sciences. | Worldwide |
| NQDI 1 | NQDI 1. Group: Biochemicals. Grades: Purified. CAS No. 175026-96-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NQDI-1 | NQDI-1 inhibits apoptosis signal-regulating kinase 1 (ASK1) with a Ki of 500 nM and an IC50 of 3 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 175026-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19566. | |
| N-(Quinolin-4-yl)acetamide | N-(Quinolin-4-yl)acetamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 32433-28-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| NR12S | NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1221739-85-0. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-162160. | |
| NR162 | NR162 is a selective CASK (Ca2+/calmodulin-dependent Ser/Thr kinase) inhibitor with an IC50 of 80 nM and a Kd of 22 nM. NR162 shows about 50-fold selectivity for CASK than TYRO3. NR162 targets the unique GFG motif of CASK and has excellent shape complementarity to the CASK ATP binding pocket. NR162 can be used for the research of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755241-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-115719. | |
| N-[(R)-1-Phenylethyl]acetamide | N-[(R)-1-Phenylethyl]acetamide. Group: Biochemicals. Alternative Names: (+)-N-(1-Phenylethyl)acetamide; (R)-1-Acetamido-1-phenylethane; (R)-N-Acetyl-1-phenylethylamine; (α R) -N- (α -Methylphenyl) acetamide. Grades: Highly Purified. CAS No. 36283-44-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide | N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (R)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 1217846-28-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences. | Worldwide |
| N(R)-(2-(Diphenylphosphino)-6-methylphenyl)-N-methyladamantan-1-amine | N(R)-(2-(Diphenylphosphino)-6-methylphenyl)-N-methyladamantan-1-amine. CAS No. 1333903-48-2. Purity: 98%. Product ID: ACM1333903482-1. Molecular formula: C30H34NP. Mole weight: 439.58. Alfa Chemistry - ISO 9001:32057 Certified. | |
| NR2F1 agonist 1 | NR2F1 agonist 1, a nuclear receptor NR2F1 agonist, specifically activates dormancy programs in malignant cells. NR2F1 agonist 1 up-regulates NR2F1 and downstream target genes that regulate dormancy. NR2F1 agonist 1 induces neural crest-like and growth suppression in head and neck squamous cell carcinoma (HNSCC) via NR2F1 activation. NR2F1 agonist 1 inhibits tumor growth in a mouse primary tumor model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 374101-64-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149913. | |
| NR2F2-IN-1 free base | NR2F2-IN-1 (free base) is a potent and selective orphan nuclear receptor COUP-TFII (NR2F2) inhibitor. NR2F2-IN-1 (free base) substantially inhibits COUP-TFII-driven NGFIA reporter expression. NR2F2-IN-1 (free base) directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators, including FOXA1, thus repressing COUP-TFII activity on target gene regulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 452087-38-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156190A. | |
| NRC-11 | NRC-11 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP1), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Ser-Val-Phe-Arg-Lys-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Leu-Asp-His-Tyr-Leu-NH2. Grade: ≥96%. Molecular formula: C129H209N37O30. Mole weight: 2758.32. | |
| NRC-12 | NRC-12 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP2), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Lys-Trp-Phe-Asn-Arg-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Val-Asp-His-Tyr-Leu-NH2. Grade: ≥97%. Molecular formula: C135H209N39O30. Mole weight: 2858.40. | |
| NRC-13 | NRC-13 is an antimicrobial peptide found in American plaice AP3, Hippoglossoides platessoides Fabricius. It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. Synonyms: H-Gly-Trp-Arg-Thr-Leu-Leu-Lys-Lys-Ala-Glu-Val-Lys-Thr-Val-Gly-Lys-Leu-Ala-Leu-Lys-His-Tyr-Leu-NH2; glycyl-L-tryptophyl-L-arginyl-L-threonyl-L-leucyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-alpha-glutamyl-L-valyl-L-lysyl-L-threonyl-L-valyl-glycyl-L-lysyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-histidyl-L-tyrosyl-L-leucinamide; (4S,7S,10S,13S,16S,19S,22S,25S,31S,34S,37S,40S,43S)-10-((1H-imidazol-5-yl)methyl)-43-((2S,5S,8S,11S,14S,17S,20S,23S)-23-((1H-indol-3-yl)methyl)-26-amino-5,8-bis(4-aminobutyl)-20-(3-guanidinopropyl)-17-((R)-1-hydroxyethyl)-11,14-diisobutyl-2-methyl-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazahexacosanamido)-13,25,37-tris(4-aminobutyl)-4-carbamoyl-7-(4-hydroxybenzyl)-34-((R)-1-hydroxyethyl)-16,22-diisobutyl-31,40-diisopropyl-2,19-dimethyl-6,9,12,15,18,21,24,27,30,33,36,39,42-tridecaoxo-5,8,11,14,17,20,23,26,29,32,35,38,41-tridecaazahexatetracontan-46-oic acid. Grade: ≥97%. Molecular formula: C125H211N35O28. Mole weight: 2652.28. | |
| NRC-17 | NRC-17 is an antimicrobial peptide found in Glyptocephalus cynoglossus L. (Witch flounder GC3.8), and has antibacterial and antifungal activity. Synonyms: H-Gly-Trp-Lys-Lys-Trp-Leu-Arg-Lys-Gly-Ala-Lys-His-Leu-Gly-Gln-Ala-Ala-Ile-Lys-Gly-Leu-Ala-Ser-OH. Grade: ≥98%. Molecular formula: C116H190N36O26. Mole weight: 2505.02. | |
| NR-CL | Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. Synonyms: Nicotinamideribosidechloride; NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl; Nicotimideribosidechloride; Pyridinium, 3-(aminocarbonyl)-1-β -D-ribofuranosyl-, chloride(1:1); 3-carbamoyChemicalbookl-1-((2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-iumchloride; 3-Carbamoyl-1-(β -D-ribofuranosyl)pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride. CAS No. 23111-00-4. Product ID: PAP-0088. Molecular formula: C11H15ClN2O5. Product Keywords: Other Active Pharmaceutical Ingredients; NR-CL; PAP-0088; ; C11H15ClN2O5; 23111-00-4. Appearance: White Powder. Chemical Name: Pyridinium,3-(aminocarbonyl)-1-β-D-ribofuranosyl-,chloride(1:1). Grade: Pharmaceutical Grade. Color: White. Solubility: Soluble to 100 mM in DMSO and to 100 mM in water. Storage: under inert gas (nitrogen or Argon) at 2-8°C. Product Description: Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. |  |
| Nrf2 activator-4 | Nrf2 activator-4 (Compound 20a) is a highly potent, orally active Nrf2 activator with an EC50 of 0.63 μM. Nrf2 activator-4 suppresses reactive oxygen species against oxidative stress in microglia. Nrf2 activator-4 effectively recovers the learning and memory impairment in a scopolamine-induced mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2383016-68-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146086. | |
| Nrf2 Activator II, AI-1 (Ethyl-4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate) | A cell-permeable chloro-quinolinone compound that selectively and covalently modifies Kelch-like ECH-associated protein 1 (Keap1)-Cys151 and represses Keap1 function and reduces Nrf2 (Nuclear factor E2-related factor 2)-Keap1 interaction. Shown to stabilize Nrf2 by inhibiting the Keap1-driven ubiquitination of Nrf2 and thereby activating the Nrf2-ARE (antioxidant response element) pathway (EC50 = 2.7uM in neuroblastoma IMR-32 cells). Offers protection against H2O2 induced oxidative stress, but unlike tert-butylhydroquinone AI-1 does not act as a free radical scavenger. Its anti-oxidant effects are mediated via Nrf2 induced antioxidant response. Does not affect mutant ARE where GC are substituted with AT within the core ARE sequence. Group: Biochemicals. Grades: Highly Purified. CAS No. 75483-04-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Nrf2 Activator III, TAT-14 Peptide, H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH | A 14-mer peptide (LQLDEETGEFLPIQ) conjugated to cell-penetrating trans-activating transcriptional activator (TAT) sequence (YGRKKRRQRRRLQ) that targets the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) binding site on Kelch-like ECH-associated protein 1 (Keap1). Competitively disrupts Nrf2-Keap1 interaction and stabilizes cytosolic Nrf2, and promotes its nuclear translocation and binding to the antioxidant response element (ARE). Exhibits anti-inflammatory properties and increases heme-oxygenase-1 gene expression (~75uM). Also shown to suppress LPS-induced TNF-a secretion in THP-1 monocytes (~ 37.5uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1362661-34-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| NRF2 Antibody [J1K11] | NRF2 Antibody [J1K11]. Group: Antibodies. Alternative Names: Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2 ; Nrf-2; Nuclear factor, erythroid derived 2, like 2 ; NFE2L2; NRF2. Pack Sizes: 20uL. Product ID: F4141. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| Nrf2 degrader 1 | Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with a DC50 of 0.1-1 μM in huH1 cells. Nrf2 degrader 1 inhibits cancer cells growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively. Nrf2 degrader 1 can be used for the study of liver cancer, non-small cell lung cancer (NSCLC) and squamous cell carcinoma of lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3025286-00-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162307. | |
| Nrf2-IN-1 | Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1610022-76-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101025. | |
| Nrf2-IN-3 | Nrf2-IN-3 (Compound R16) is a small-molecule NRF2 inhibitor and increases reactive oxygen species (ROS) production. Nrf2-IN-3 selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions, leading to proteasome-dependent NRF2 degradation in cells. Nrf2-IN-3 sensitizes KEAP1-mutated tumor cells to Cisplatin (HY-17394), Gefitinib (HY-50895), and KEAP1 G333C-mutated xenograft to Cisplatin [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6325-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-149508. | |
| NRG1271 | NRG1271 is an orally active mitochondrial permeability transition pore (mPTP) inhibitor with blood-brain barrier penetration. NRG1271 can be used for the study of Neurological Disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077720-24-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175715. | |
| N-(R)-Glycidyl Phthalimide | Reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants. Group: Biochemicals. Alternative Names: 2-[(2R)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione; (R)-2-(Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione; (R)-N-(2,3-Epoxypropan-1-yl)phthalimide; N-((2R)-Oxiran-2-ylmethyl)phthalimide. Grades: Highly Purified. CAS No. 181140-34-1. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| NRL-1049 | NRL-1049 (BA-1049 (free base)) is an orally available and selective ROCK2 inhibitor with IC50 values of 0.59?μM for ROCK2 and 26?μM for ROCK1, respectively. NRL-1049 modulates ROCK signaling, preserves blood-brain barrier integrity, reduces edema, seizures and hemorrhage, and alleviates cerebral cavernous malformation lesion burden. NRL-1049 can be used for the study of acute brain injury, ischemic stroke, and cerebral cavernous malformations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BA-1049 free base. CAS No. 1973494-16-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162596. | |
| NRL-1049 dihydrochloride | NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 (ROCK2) inhibitor with an IC50 of 0.59 μM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 (IC50 = 26 μM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BA-1049. CAS No. 1973494-17-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126432. | |
| NRPE | NRPE. Group: Biochemicals. Alternative Names: (all-E)-1,2-di-2-palmitin. Grades: Highly Purified. CAS No. 30576-47-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C57H100NO8P. US Biological Life Sciences. | Worldwide |
| N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH | N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH is a specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) with a Ki of 0.027±0.003 μM. Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts it into a potent inhibitor of angiotensin-converting enzyme (ACE). Synonyms: Cpp-AAF-pAb; Cfp-aaf-pab; N-(1-Carboxy-3-phenylpropyl)-ala-ala-phe-p-aminobenzoate; N-(1-Carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate; L-Phenylalaninamide, N-(1-carboxy-3-phenylpropyl)-L-alanyl-L-alanyl-N-(4-carboxyphenyl)-; N-(1-Carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide. Grade: ≥95%. CAS No. 116560-97-5. Molecular formula: C32H36N4O7. Mole weight: 588.66. | |
| N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide | N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide. Synonyms: N-((RS)-2-Hydroxy-propyl)-VL-anilide; L-Leucinamide, N-(2-hydroxypropyl)-L-valyl-N-phenyl- (9CI). CAS No. 282726-24-3. Molecular formula: C20H33N3O3. Mole weight: 363.49. | |
| N-rt-Butyloxycarbonyl Gabapentin | Protected Gabapentin. Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-[[[ (1, 1-Dimethylethoxy) carbonyl]amino]methyl]-cyclohexaneacetic Acid; 2- [1- [ (tert-Butoxycarbonylamino) methyl] cyclohexyl] acetic Acid; [1- (tert-Butoxycarbonylamino methyl ) cyclohexyl] acetic Acid. Grades: Highly Purified. CAS No. 227626-60-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| NRTN (Neurturin), Human | It is a cell-penetrating peptide (CPP) derived from human neurturin protein. NRTN can permeate cell membrane at low micromolar concentration and has no obvious effect on cell membrane. NRTN has high activity as a siRNA transfection reagent. Synonyms: H-Gly-Ala-Ala-Glu-Ala-Ala-Ala-Arg-Val-Tyr-Asp-Leu-Gly-Leu-Arg-Arg-Leu-Arg-Gln-Arg-Arg-Arg-Leu-Arg-Arg-Glu-Arg-Val-Arg-Ala-OH. Grade: >98%. Molecular formula: C150H268N64O39. Mole weight: 3592.20. | |
| Nru I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 50% of the dna fragments can be ligated and 90% of them can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 500 U; 2500U. TCG↑CGA AGC↓GCT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Nocardia rubra. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1142RE. |  |
| NR-V04 | NR-V04 is a selective NR4A1 PROTAC degrader. NR-V04 forms a ternary complex with NR4A1 and the VHL E3 ligase, mediates proteasome-dependent degradation of NR4A1. NR-V04 induces tumor-infiltrating B cells and effector memory CD8+ T cells and reduces monocytic myeloid-derived suppressor cells in tumor microenvironments. NR-V04 can be used for the research of melanoma and colon cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766608-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159779. | |
| NRWC | NRWC is an antimicrobial peptide found in Bacillus subtilis, and has antibacterial activity. Synonyms: Asn-Arg-Trp-Cys-Phe-Ala-Gly-Asp-Asp; NRWC (Bacteriocin). Grade: >98%. Molecular formula: C46H62N14O15S. Mole weight: 1083.14. | |
| NRX-103094 | NRX-103094 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763260-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141449. | |
| NRX-1532 | NRX-1532 is a small molecule enhancer of β-catenin:β-TrCP interaction. Uses: Scientific research. Category: Signaling pathways. CAS No. 3083833-54-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144982. | |
| NRX-252114 | NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763260-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111836. | |
| NRX-252262 | NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2438637-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111760. | |
| NRX-2663 | NRX-2663 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC50 of 22.9 μM and a Kd of 54.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763260-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141448. | |
| NS | NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase. | |
| NS 11021 | NS 11021 is a potent and specific Ca2+-activated big-conductance K+ Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 956014-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13103. | |
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