A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
N-Undecanoylglycine is an ester product. Uses: Scientific research. Category: Signaling pathways. CAS No. 83871-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-166240.
N-undecylamine
N-undecylamine. Alternative Names: 1-Undecylamine. CAS No. 7307-55-3. Molecular formula: C11H25N. Mole weight: 171.32. Purity: 98%. SMILES: CCCCCCCCCCCN. InChI: InChI=1S/C11H25N/c1-2-3-4-5-6-7-8-9-10-11-12/h2-12H2,1H3.
Nuovo-Proline-16 is a C16, C16 carboxyl derivative of the amino acid hydroxypro-line. Dipalmitoyl hydroxyproline promotes collagen synthesis and enhances skin tone. Uses: Anti-wrinkle, Skin tightening, Lip plumping. Group: Skin Care Active Ingredients. INCI Name: Dipalmitoyl hydroxyproline. CAS Number: 41672-81-5.
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Nurr1 agonist 2
Nurr1 agonist 2 (Compound 7) is a Nurr1 agonist (EC50: 0.07 μM). Nurr1 agonist 2 binds to the recombinant Nurr1 ligand binding domain (LBD) with a Kd value of 0.14 μM. Nurr1 agonist 2 increases the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) mRNA expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 742058-34-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W677684.
Nurr1 agonist 4
Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 87645-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-149867.
Nurr1 agonist 7
Nurr1 agonist 7 (compound 110) is a Nurr1 agonist with an EC50 value of 0.12 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 228707-95-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-157026.
Nurr1 inverse agonist-1
Nurr1 inverse agonist-1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1. Uses: Scientific research. Category: Signaling pathways. CAS No. 2758673-07-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132909.
Nusinersen
Nusinersen is a modified antisense oligonucleotide, where the 2'-hydroxy groups of the ribofuranosyl rings are replaced with 2'-O-2-methoxyethyl groups and the phosphate linkages are replaced with phosphorothioate linkages. Nusinersen binds to a specific sequence in the intron downstream of exon 7 of the SMN2 transcript. Nusinersen is a drug used for the treatment of spinal muscular atrophy (SMA), which is related to the mutation in the SMN1 gene. It was approved by FDA in Dec. 2016 for the treatment of SMA in adults and children. Uses: The treatment of sma. Alternative Names: RNA [2'-O-(2-methoxyethyl)](P-thio)(m5U-m5C-A-m5C-m5U-m5U-m5U-m5C-A-m5U-A-A-m5U-G-m5C-m5U-G-G); Spinraza; ISIS 396443; 1: PN: WO2010148249 SEQID: 1 claimed DNA. Grades: ≥95%. CAS No. 1258984-36-9. Molecular formula: C234H340N61O128P17S17. Mole weight: 7127.30.
Nusinersen
Nusinersen is an antisense oligonucleotide active molecule. Nusinersen modifies the pre-messenger RNA splicing of the SMN2 gene, thereby promoting the production of full-length SMN protein. Nusinersen improves spinal muscular atrophy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1258984-36-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112980.
Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 μM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches. Alternative Names: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one. Grades: >98%. CAS No. 548472-68-0. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49.
Nutlin-3
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells. Group: Inhibitors. CAS No. 890090-75-2. Pack Sizes: 5mg. Product ID: S1061. Formula: C30H30Cl2N4O4. Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Nutlin-3
Nutlin-3 is a commercial available p53-MDM2 inhibitor, with Ki of 90 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 548472-68-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50696.
Nutlin-3a
Nutlin-3a is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin-3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Alternative Names: rebemadlin; (-)-Nutlin-3; Nutlin-3a chiral. Grades: 95%. CAS No. 675576-98-4. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.5.
Nutlin-3a
Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rebemadlin. CAS No. 675576-98-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10029.
Nutlin-3a
Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner. Group: Inhibitors. Alternative Names: (-)-Nutlin-3. CAS No. 675576-98-4. Pack Sizes: 5mg. Product ID: S8059. Formula: C30H30Cl2N4O4. Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Nutlin-3b
Nutlin-3b, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. Alternative Names: Nutlin-3; nutlin 3; Nutlin 3b; FJA1772CVW; (+)-Nutlin-3; CHEMBL2152332; CHEBI:46742; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one; 2-Piperazinone, 4-(((4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1H-imidazol-1-yl)carbonyl)-; 4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one; 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone; cis-4-{[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl}piperazin-2-one. Grades: >98%. CAS No. 675576-97-3. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49.
Nutlin-3b
Nutlin-3b, the inactive form of Nutlin-3 (HY-50696), is a p53/MDM2 inhibitor with an IC50 of 13.6 μM. Nutlin-3b is 150 times less potent in binding to MDM2 than Nutlin-3a (HY-10029). Nutlin-3b is promising for research of cancers[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 675576-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15335.
Nutmeg Neolignan
Nutmeg Neolignan is a stereomixture of erythro-Δ8'-7-Ethoxy-4-hydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan and threo-Δ8'-7-Ethoxy-4-hydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan. The mixture is novel TRPM8 agonist from nutmeg as promising cooling compound. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C46H60O12, Molecular Weight: 804.96. US Biological Life Sciences.
Worldwide
Nutmeg oil
Nutmeg oil. Alternative Names: Nutmegoil,terpeneless. CAS No. 8008-45-5. Purity: 0.98. Product ID: CI-EO-0054. Molecular formula: C32H56. Mole weight: 440.8 g/mol. IUPAC Name: 2,2-dimethyl-3-methylidenebicyclo[2.2.1]heptane;(4R,6R)-1,6-dimethyl-4-propan-2-ylcyclohexene;(2R,4R)-2-methyl-1-methylidene-4-propan-2-ylcyclohexane. Alfa Chemistry - ISO 9001:32057 Certified.
"""Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages""". Uses: Oral care and pharmaceutical, Aromatherapy, Personal Care, Perfumery. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-005. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia.
New Jersey
Nutmeg Oil (Java | Bogor 9% Myristicin)
Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages. Uses: Flavor, Oral Care, Fragrance Products, Personal Care. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-001. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia.
New Jersey
Nutmeg Oil Safrole Free
"Indonesia is currently the largest producer of Nutmeg Oil in the world, providing 75% to 80% of the global supply. It is also one the top three largest producers of Mace Oil. The three areas where Nutmeg is mainly grown in Indonesia are Java, Aceh in North Sumatra and the spice island in around Sulawesi. 80 - 90% of the Nutmeg Oil processed is used for flavouring in beverages". Uses: Fragrance, Personal Care. Group: Plant Extracts. INCI Names: Myristica Fragrans (Nutmeg) Kernel Oil. Grades: FOOD GRADE. CAS No. 84082-68-8 ; 8008-45-5. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: NM-004. Olfactive Profile: Spicy, terpenic, sweet, warm, woody. EC No: 282-013-3. FEMA No: 2793. Origin: Indonesia.
NV03 is a potent and selective antagonist of Ubiquitin-like with PHD and RING finger domains 1 (UHRF1)-H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a Kd of 2.4 μM. NV03 is also a ligand for E3 ligase. NV03 can be studied in anticancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2448341-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125292.
NV-354
NV-354 (Mitochondria modulator-1) (compound 1) is a mitochondrial regulator that stimulates mitochondrial ATP production. NV-354 has good oral bioavailability, blood-brain barrier permeability, and good plasma stability. NV-354 has the potential to study mitochondrial diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitochondria modulator-1. CAS No. 866465-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-153715.
NV-5138
NV-5138, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 possesses rapid antidepressant effects. Alternative Names: 4-(difluoromethyl)-L-leucine; ((S)-2-Amino-5,5-difluoro-4,4-dimethylpentanoic acid. Grades: ≥98%. CAS No. 2095886-80-7. Molecular formula: C7H13F2NO2. Mole weight: 181.18.
NV914
NV914 is an inhibitor of FTSJ1 (tryptophan tRNA-specific 2'-O-methyltransferase) that inhibits the methyltransferase activity of FTSJ1, induces translational readthrough of premature termination codons, and enables genes carrying nonsense mutations to synthesize full-length proteins. NV914 belongs to translational readthrough-inducing compounds (TRIDs). NV914 exhibits translational readthrough activity against nonsense mutations in in vitro systems, does not induce readthrough of natural termination codons, and restores CFTR protein expression. NV914 shows favorable acute oral tolerance in mice, with low health risks and good safety profiles. NV914 is applicable to research related to cystic fibrosis and Shwachman-Diamond syndrome[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2341941-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-177963.
N-Valeryl-D-glucosamine
N-Valeryl-D-glucosamine, an imperative compound widely employed in the biomedical sector, is esteemed for its tremendous prospects in the pharmaceutical arena. Its significance lies in the development of therapeutic agents targeting diverse ailments encompassing inflammation and autoimmune disorders. Alternative Names: 2-Deoxy-2-valeramido-D-glucopyranose; 2-Deoxy-2-pentanamido-D-glucopyranose; N-((3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)pentanamide. CAS No. 63223-57-4. Molecular formula: C11H21NO6. Mole weight: 263.29.
N-valeryl-D,L-penicillamine
N-valeryl-D,L-penicillamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
N-Valinyl-1-deoxy-D-glucitol
N-Valinyl-1-deoxy-D-glucitol is an exceptional biomedical compound, demonstrating remarkable potential in the research for diabetes. It serves as a potent α-glucosidase inhibitor. Alternative Names: N-Glucosyl-L-valine. Molecular formula: C11H23NO7. Mole weight: 281.30.
N-Vanillyldecanamide
N-Vanillyldecanamide is found in the fruits of Capsicum annuum L. var. annuum. Alternative Names: Decylic acid vanillylamide. Grades: > 95%. CAS No. 31078-36-1. Molecular formula: C18H29NO3. Mole weight: 307.43.
N-Vanillylnonanamide
1g Pack Size. Group: Biochemicals, Organics, Research Organics & Inorganics. Formula: C17H27NO3. CAS No. 2444-46-4. Prepack ID 28253688-1g. Molecular Weight 293.4. See USA prepack pricing.
N-vinyl-2-pyrrolidinone copolymer
N-vinyl-2-pyrrolidinone copolymer. CAS No. 25086-89-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
N-Vinyl-2-pyrrolidone
N-Vinyl-2-pyrrolidone. Group: Biochemicals. Alternative Names: 1-Vinyl-2-pyrrolidinone; 1-Vinylpyrrolidin-2-one. Grades: Highly Purified. CAS No. 88-12-0. Pack Sizes: 1kg, 2kg, 5kg. US Biological Life Sciences.
Worldwide
N-Vinyl-2-pyrrolidone 99+% (GC)
N-Vinyl-2-pyrrolidone 99+% (GC). Group: Biochemicals. Grades: GC. CAS No. 88-12-0. Pack Sizes: 100g, 250g, 1Kg, 4Kg, 5Kg. US Biological Life Sciences.
Worldwide
N-Vinyl-2-pyrrolidone, NVP
N-Vinyl-2-pyrrolidone, NVP. Applications: N-vinyl-2-pyrrolidone (nvp) is commonly used as a reactive diluent for radiation curing in uv-coating, uv-inks, and uv adhesives. it is used as a monomer to produce water soluble polyvinylpyrrolidone (pvp) with uses in pharmaceuticals, oil field, cosmetics, food additives & adhesives. it is used in the manufacture of copolymers with, for example, acrylic acid, acrylates, vinyl acetate and acrylonitrile and in the synthesis of phenolic resins. Category: Pharmaceutical excipients. Synonyms: 1-VINYL-2-PYRROLIDINONE, 99+%;N-Vinyl-2-pyrrolidone, stabilized with Kerobit;N-Vinyl-2-pyrrolidone, stabilized, 98%;N-VINYL-2-PYRROLIDINONE;N-VINYL-2-PYRROLIDONE;N-VINYLPYRROLIDONE;N-VINYLBUTYROLACTAM;1-ethenyl-2-pyrrolidinon. Grades: DMF. CAS No. 88-12-0. Product ID: PIE-0030. Molecular formula: C6H9NO. Mole weight: 111.14. Appearance: Colorless to yellow liquid.
N-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine)
N-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine). Alternative Names: 1-Ethenyl-2-pyrrolidinone. CAS No. 88-12-0. Purity: >99.0%. Product ID: FFC-AR-88120. Molecular formula: C6H9NO. Mole weight: 111.14. IUPAC Name: 1-ethenylpyrrolidin-2-one. Alfa Chemistry - ISO 9001:32057 Certified.
100g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H13NO. CAS No. 2235-00-9. Prepack ID 90026843-100g. Molecular Weight 139.19. See USA prepack pricing.
1g Pack Size. Group: Building Blocks, Organics. Formula: C10H7NO2. CAS No. 3485-84-5. Prepack ID 89997051-1g. Molecular Weight 173.17. See USA prepack pricing.
N-Vinylphthalimide
Off-white powder, 97%. Synonym: 2-Ethenylisoindoile-1,3-dione. CAS No. 3485-84-5. Pack Sizes: Typically in stock: 25g, 100g. Mole weight: 173.17. MP/BP: M.P. 85-87. Order No: FR-2735.
Polyvinylpyrrolidone is a white powder. Compatible with a wide range of hydrophilic and hydrophobic resins. (NTP, 1992);Liquid;White or nearly white powder;YELLOW-TO-BROWN HYGROSCOPIC POWDER.;COLOURLESS-TO-YELLOW LIQUID.;White powder. Molecular formula: (C6H9NO)n;C6H9NO;C6H9NO. Mole weight: 111.14g/mol. IUPAC Name: 1-ethenylpyrrolidin-2-one. SMILES: C=CN1CCCC1=O. InChI: InChI=1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2.
n-vinylpyrrolidone/styrene copolymer
n-vinylpyrrolidone/styrene copolymer. CAS No. 25086-29-7. Molecular formula: C14H17NO.
N-Vinylpyrrolidone Technical 95%min
N-Vinylpyrrolidone Technical 95%min.
NVP-2
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces cell apoptosis.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263373-43-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12214A.
NVP 231
NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 362003-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13945.
NVP 231
NVP 231. Group: Biochemicals. Grades: Purified. CAS No. 362003-83-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NVP-231
NVP-231. Group: Biochemicals. Alternative Names: N-[2-(Benzoylamino)-6-benzothiazolyl]-tricyclo[3.3.1.13, 7]decane-1-carboxamide; NVP 231. Grades: Highly Purified. CAS No. 362003-83-6. Pack Sizes: 10mg. Molecular Formula: C25H25N3O2S, Molecular Weight: 431.55. US Biological Life Sciences.
Worldwide
NVP ADW 742
NVP ADW 742. Group: Biochemicals. Grades: Purified. CAS No. 475488-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
NVP-ADW742
NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADW742; GSK 552602A; ADW. CAS No. 475488-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10252.
NVP-AEW541
NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEW541. CAS No. 475489-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50866.
NVP-BAG956
NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50s of 34, 56, 112 and 444 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAG 956. CAS No. 853910-02-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13333.
Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Alternative Names: Infigratinib phosphate; BGJ-398 phosphate; NVP-BGJ398 phosphate; NVPBGJ398 phosphate. Grades: >98%. CAS No. 1310746-10-1. Molecular formula: C26H34Cl2N7O7P. Mole weight: 658.47.
NVP BHG 712
NVP BHG 712. Group: Biochemicals. Grades: Purified. CAS No. 940310-85-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
NVP-BHG712
NVP-BHG712 is an oral active EphB4 kinase autophosphorylation inhibitor, with IC50 values of 3.3 nM and 3.0 nM for EphA2 and EphB4, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BHG712. CAS No. 940310-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13258A.
NVP-BSK805
NVP-BSK805, a quinoxaline derivative, is a selective ATP-competitive JAK2 inhibitor which could induce apoptosis (GI50 < 100 nM) and restrain the growth of JAK2V617F cells (Ba/F3). Alternative Names: 4-(2,6-difluoro-4-(3-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)quinoxalin-5-yl)benzyl)morpholine; BSK 805; 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1H-pyrazol-4-yl)quinoxaline. Grades: 98%. CAS No. 1092499-93-8. Molecular formula: C27H28F2N6O. Mole weight: 490.55.