A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A metabolite of Mebeverine, an antispasmodic. Group: Biochemicals. Alternative Names: 4-[Ethyl[2-(4-hydroxyphenyl)-1-methylethyl]amino] Butanoic Acid. Grades: Highly Purified. CAS No. 586357-02-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
O-Desmethyl metoclopramide hydrochloride
O-Desmethyl metoclopramide hydrochloride. Group: Biochemicals. Alternative Names: 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy-benzamide hydrochloride. Grades: Highly Purified. CAS No. 38059-78-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C13H21Cl2N3O2. US Biological Life Sciences.
Worldwide
O-Desmethyl Metoclopramide, Hydrochloride
A metabolite of Metoclopramide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Metoprolol
A metabolite of Metoprolol. Group: Biochemicals. Alternative Names: 4-[2-Hydroxy-3-[ (1-methylethyl) amino]propoxy]-benzeneethanol; (+/-) -4-[2-Hydroxy-3- (isopropylamino) propoxy]phenylethyl Alcohol; (+/-)-O-Demethylmetoprolol; H 105/22; SL 80-0088. Grades: Highly Purified. CAS No. 62572-94-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Metoprolol-d5
A metabolite of Metoprolol. Group: Biochemicals. Alternative Names: 4-[2-Hydroxy-3-[ (1-methylethyl) amino]propoxy]-benzeneethanol-d5; (+/-) -4-[2-Hydroxy-3- (isopropylamino) propoxy]phenylethyl Alcohol-d5; (+/-)-O-Demethylmetoprolol-d5; H 105/22-d5; SL 80-0088-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Midostaurin
O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGP62221; O-Desmethyl PKC412. CAS No. 740816-86-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-129491.
O-Desmethyl mycophenolate mofetil(impurity A)
O-Desmethyl mycophenolate mofetil(impurity A). Group: Biochemicals. Alternative Names: Mycophenolate mofetyl impurity A. Grades: Highly Purified. CAS No. 1322681-36-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H29NO7. US Biological Life Sciences.
Worldwide
O-Desmethyl Mycophenolate Mofetil (Impurity A)
Mycophenolate mofetyl impurity A. Group: Biochemicals. Alternative Names: Mycophenolate Mofetyl Impurity A. Grades: Highly Purified. CAS No. 1322681-36-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Mycophenolic Acid
A metabolite of Mycophenolic acid (phase 1 metabolite). Group: Biochemicals. Alternative Names: (4E)-6-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid; Demethylmycophenolic Acid; Nor-O-methyl Mycophenolic Acid. Grades: Highly Purified. CAS No. 31858-65-8. Pack Sizes: 1mg. US Biological Life Sciences.
Protected, labeled metabolite of Mycophenolic Acid. Group: Biochemicals. Alternative Names: (4E)-6-(1,3-Dihydro-4,6-dihydroxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid Methyl Ester-d3; Demethylmycophenolic Acid Methyl Ester-d3; Nor-O-methyl Mycophenolic Acid Methyl Ester-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
O-Desmethyl-N-deschlorobenzoyl Indomethacin
A metabolite of Indomethacin. Group: Biochemicals. Alternative Names: 5-Hydroxy-2-methyl-1H-indole-3-acetic Acid; DMBI. Grades: Highly Purified. CAS No. 50995-53-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Pyrilamine
A metabolite of the antihistamine Pyrilamine. Group: Biochemicals. Alternative Names: 4- [ [ [2- (Dimethylamino) ethyl] -2-pyridinylamino] methyl] phenol. Grades: Highly Purified. CAS No. 57830-29-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Pyrilamine
O-Desmethyl Pyrilamine. Alternative Names: 4-[[[2-(Dimethylamino)ethyl]-2-pyridinylamino]methyl]phenol. CAS No. 57830-29-2. Purity: 98%. Product ID: ACM57830292. Molecular formula: C16H21N3O. Mole weight: 271.36. Alfa Chemistry - ISO 9001:32057 Certified.
O-Desmethyl Quinidine
A metabolite of Quinidine. Group: Biochemicals. Alternative Names: (9S)-9-Diol Cinchonan-6; 6-Hydroxycinchonine; Cupreidine; O-Demethylquinidine. Grades: Highly Purified. CAS No. 70877-75-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Quinidine
O-Desmethyl Quinidine. Alternative Names: 6'-Hydroxycinchonine. CAS No. 70877-75-7. Purity: 95%. Product ID: ACM70877757. Molecular formula: C19H22N2O2. Mole weight: 310.39. Alfa Chemistry - ISO 9001:32057 Certified.
O-Desmethyl Quinine
A metabolite of Quinine. Group: Biochemicals. Alternative Names: (8,9R)-9-Diol Cinchonan-6; Cupreine; O-Demethylquinidine; Ultraquinine. Grades: Highly Purified. CAS No. 524-63-0. Pack Sizes: 5mg, 50mg, 500mg. Molecular Formula: C??H??N?O?, Form: Supplied as a off-white to pale yellow. US Biological Life Sciences.
Worldwide
O-Desmethyl Thebainone
O-Desmethyl Thebainone is an analogue of Thebainone (T342500). Thebainone is a metabolite of Thebaine (T342450) which is an opiate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C17H20BrNO3. US Biological Life Sciences.
Worldwide
O-Desmethyl Venlafaxine Cyclic Impurity
O-Desmethyl Venlafaxine Cyclic Impurity is a cyclic impurity of O-Desmethylvenlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Alternative Names: 5-(4-Hydroxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane; 4-(3-Methyl-1-oxa-3-azaspiro[5.5]undecanyl)phenol. CAS No. 1346601-55-5. Molecular formula: C16H23NO2. Mole weight: 261.37.
O-Desmethyl venlafaxine dimer
O-Desmethyl venlafaxine dimer. Group: Biochemicals. Alternative Names: 2, 2'-methylenebis[4-[2- (dimethylamino) -1- (1-hydroxycyclohexyl) ethyl]phenol. Grades: Highly Purified. CAS No. 1187545-62-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C33H50N2O4. US Biological Life Sciences.
Worldwide
O-Desmorpholinopropyl Gefitinib
A metabolite of Gefitinib. Group: Biochemicals. Alternative Names: 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol;4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline. Grades: Highly Purified. CAS No. 184475-71-6. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
O-Desulfo Micafungin
O-Desulfo Micafungin is an impurity of caspofungin or micafungin. Micafungin is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. Alternative Names: Micafungin (m1); Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)-; 1-((4R,5R)-4,5-Dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)pneumocandin A0. CAS No. 539823-80-8. Molecular formula: C56H71N9O20. Mole weight: 1190.23.
Odevixibat
Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A4250. CAS No. 501692-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109120.
OdG1
OdG1 is an antimicrobial peptide found in Odorrana grahami (Rana grahami, Yunnanfu frog), and has antibacterial and antifungal activity. Alternative Names: Odorranain-G1; Odorranain-G1 antimicrobial peptide; Phe-Met-Pro-Ile-Leu-Ser-Cys-Ser-Arg-Phe-Lys-Arg-Cys (Disulfide bridge: Cys7-Cys13). Grades: ≥97%. Molecular formula: C70H112N20O16S3. Mole weight: 1585.97.
O-(D-Glucopyranosylidene)amino N-phenylcarbamate
O-(D-Glucopyranosylidene)amino N-phenylcarbamate is a potential compound aiding in the research of various diseases such as cancers, infectious diseases and autoimmune disorders. Alternative Names: Gluconophylurethane; Gluconohydroximo-1,5-lactone-N-phenylurethane; GHLPU. CAS No. 104012-84-2. Molecular formula: C13H16N2O7. Mole weight: 312.28.
o-Dianisidine
3,3'-dimethoxybenzidine appears as colorless crystals or a light brown powder. Turns violet on standing. Carcinogen.;COLOURLESS CRYSTALS.;Colorless crystals that turn a violet color on standing.;Colorless crystals that turn a violet color on standing. [Note: Used as a basis for many dyes.]. CAS No. 119-90-4. Molecular formula: C14H16N2O2;C14H16N2O2. Mole weight: 244.29g/mol. IUPAC Name: 4-(4-amino-3-methoxyphenyl)-2-methoxyaniline. SMILES: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)OC)N. InChI: InChI=1S/C14H16N2O2/c1-17-13-7-9(3-5-11(13)15)10-4-6-12(16)14(8-10)18-2/h3-8H,15-16H2,1-2H3.
o-Dianisidine Dihydrochloride
3,3'-dimethoxybenzidine dihydrochloride is an off-white powder. (NTP, 1992);DryPowder; Liquid. CAS No. 20325-40-0. Molecular formula: C14H18Cl2N2O2. Mole weight: 317.2g/mol. IUPAC Name: 4-(4-amino-3-methoxyphenyl)-2-methoxyaniline;dihydrochloride. SMILES: COC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)OC)N.Cl.Cl. InChI: InChI=1S/C14H16N2O2.2ClH/c1-17-13-7-9(3-5-11(13)15)10-4-6-12(16)14(8-10)18-2;;/h3-8H,15-16H2,1-2H3;2*1H.
o-Dianisidine (Fast Blue B)
o-Dianisidine has been used for neutrophil myeloperoxidase activity (MPO) assay; used for staining erythrocytes; constituent in neutral benzidine staining of dried blood smears. Group: Biochemicals. Alternative Names: 3,3'-Dimethoxybenzidine; Fast Blue B; 4,4'-Diamino-3,3'-dimethoxybiphenyl. Grades: Highly Purified. CAS No. 119-90-4. Pack Sizes: 25g, 100g. Molecular Formula: C14H16N2O2, Molecular Weight: 244.3. US Biological Life Sciences.
Worldwide
O-Dichlorobenzene
O-Dichlorobenzene. Group: Biochemicals. Alternative Names: 1,2-DICHLOROBENZENE. Grades: Highly Purified. CAS No. 95-50-1. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H4Cl2. US Biological Life Sciences.
Worldwide
o-dihydroxycoumarin 7-O-glucosyltransferase
Converts the aglycone daphetin into daphnin and, more slowly, esculetin into cichoriin, umbelliferone into skimmin, hydrangetin into hydrangin and scopoletin into scopolin. Group: Enzymes. Synonyms: uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase; UDP-glucose:o-dihydroxycoumarin glucosyltransferase. Enzyme Commission Number: EC 2.4.1.104. CAS No. 74114-37-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2332; o-dihydroxycoumarin 7-O-glucosyltransferase; EC 2.4.1.104; 74114-37-7; uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase; UDP-glucose:o-dihydroxycoumarin glucosyltransferase. Cat No: EXWM-2332.
O-(Diphenylphosphinyl)hydroxylamine
O-(Diphenylphosphinyl)hydroxylamine (CAS# 72804-96-7) is a versatile reactant used in the synthetic preparation of various products such as trans-acylaziridines and aldohydrazones. Alternative Names: O-diphenylphosphorylhydroxylamine; O-diphenylphosphorylhydroxylamine. CAS No. 72804-96-7. Molecular formula: C12H12NO2P. Mole weight: 233.20.
O-Diphenylphosphinyl hydroxylamine
O-Diphenylphosphinyl hydroxylamine. Group: Biochemicals. Alternative Names: O- (Diphenylphosphinyl) hydroxylamine. Grades: Highly Purified. CAS No. 72804-96-7. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H12NO2P. US Biological Life Sciences.
Worldwide
Oditrasertib
Oditrasertib (SAR443820) is an orally active, BBB-penetrable and selective reversible inhibitor of RIPK1. Oditrasertib can be used in the research of chronic inflammatory central nervous system diseases, such as amyotrophic lateral sclerosis and multiple sclerosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR443820; DNL788. CAS No. 2252271-93-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148787.
OdM1
OdM1 is an antimicrobial peptide found in Odorrana grahami (Rana grahami, Yunnanfu frog), and has antibacterial and antifungal activity. Alternative Names: Odorranain-M1; Odorranain-M1 antimicrobial peptide; Ala-Thr-Ala-Trp-Asp-Phe-Gly-Pro-His-Gly-Leu-Leu-Pro-Ile-Arg-Pro-Ile-Arg-Ile-Arg-Pro-Leu-Cys-Gly-Lys-Asp-Lys-Ser. Grades: ≥96%. Molecular formula: C142H228N42O35S. Mole weight: 3115.69.
ODM-201
ODM-201 is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR. Alternative Names: ODM-201; ODM 201; ODM201. Grades: 98%. CAS No. 1297538-32-9. Molecular formula: C19H19ClN6O2. Mole weight: 389.85.
ODM-201 (Darolutamide)
Darolutamide (ODM-201, BAY-1841788) is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. Phase 3. Group: Inhibitors. Alternative Names: BAY-1841788. CAS No. 1297538-32-9. Pack Sizes: 5mg. Product ID: S7559. Formula: C19H19ClN6O2. Smiles: CC(CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=NNC(=C3)C(C)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol
O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 171285-25-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W784557.
ODN 1018
ODN 1018, a Th1-biasing synthetic toll-like receptor 9 (TLR9) agonist, is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ODN 1018 signals via Toll-like receptor 9 (TLR9) to induce immunoglobulin production by B cells and interferon (IFN-α), IFN-β, interleukin-12 (IL-12), and tumor necrosis factor-α (TNF-α) by plasmacytoid dendritic cells (pDC). ISS ODN 1018 promotes antigen presentation and co-stimulatory molecular expression. It can be used as a vaccine adjuvant. Alternative Names: 1018 ISS; CpG 1018; CpG1018; CpG-1018; ODN-1018; ODN1018; DNA, d(P-thio)(T-G-A-C-T-G-T-G-A-A-C-G-T-T-C-G-A-G-A-T-G-A); CpG B class ODN 1018; CpG ODN 1018; ISS 1018; 1018ISS. Grades: ≥95%. CAS No. 937402-51-2. Mole weight: 8272.3.
ODN 1018
ODN 1018 (1018 ISS) is a TLR9 agonist and immune modulator. ODN 1018 exhibits adjuvant activity and augments CD8+ T cell responses with LNP-encapsulated OVA peptides. ODN 1018 triggers sustained suppression of allergic airway inflammation. ODN 1018 can be used for the research of allergic asthma and systemic lupus erythematosus[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1018 ISS. CAS No. 937402-51-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150724.
ODN 1018 sodium
ODN 1018 sodium.
ODN 1585
ODN 1585 is a class A CpG ODN specific to mouse Toll-like receptor 9 (TLR9). ODN 1585 is a potent inducer of IFN and TNFα production, a potent stimulator of NK (natural killer), and can be used as a vaccine adjuvant.ODN 1585 enhances the function of CD8+ T cells, including CD8+ T cell-mediated IFN-γ production. ODN 1585 induces regression of established melanomas in mice and has been shown to inhibit malaria in mice. ODN 1585 can be used to study acute myelogenous leukemia (AML) and malaria. Alternative Names: DNA, d(G-sp-G-G-G-T-C-A-A-C-G-T-T-G-A-G-G-sp-G-sp-G-sp-G-sp-G); ODN1585; ODN-1585; CpG ODN 1585; CpG 1585; ODN 1585-Murine TLR9 Agonist Controls and Conjugates (Antigen Grade). Grades: ≥95%. CAS No. 386832-46-8. Mole weight: 6430.
ODN 1585
ODN 1585 is a potent inducer of IFN and TNFα production. ODN 1585 is a potent stimulator of NK (natural killer) function. ODN 1585 increases CD8+ T-cell function, including the CD8+ T cell-mediated production of IFN-γ. ODN 1585 induces regression of established melanomas in mice. ODN 1585 can confer complete protection against malaria in mice. ODN 1585 can be used for acute myelogenous leukemia (AML) and malaria research. ODN 1585 can be used as a vaccine adjuvant[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 386832-46-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150725.
ODN 1668
ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 is an immunostimulatory sequence and can be used as an vaccine adjuvant. Alternative Names: DNA, d(P-thio)(T-C-C-A-T-G-A-C-G-T-T-C-C-T-G-A-T-G-C-T); ODN1668; ODN-1668; CpG ODN 1668; CpG 1668; ODN 1668-Type B (murine). Grades: ≥95%. CAS No. 1186063-66-0. Mole weight: 6364.1.
ODN 1668
ODN 1668, a class B CpG ODN (oligodeoxynucleotide), is a TLR-9 agonist. ODN 1668 has strong immune regulatory properties, can enhance the level of antibody IgG2 subtype, promote the immune response of T cells and B cells, and can be used in the study of vaccine adjuvants. In addition, CpG ODN 1668 induces an antimicrobial immune response via a CaTLR9 dependent pathway in groupers. Sequence: 5'-tccatgacgttcctgatgct-3[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1186063-66-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150726.
ODN 1826
ODN 1826, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist that ameliorates cardiac dysfunction after trauma-hemorrhage. ODN 1826 is an excellent immunostimulator that induces NO and iNOS production in the murine model. It enhances cell apoptosis. Alternative Names: CpG ODN 1826; ODN 1826; CpG 1826; CpG1826; INX-1826; DNA, d(P-thio)(T-C-C-A-T-G-A-C-G-T-T-C-C-T-G-A-C-G-T-T). Grades: ≥90%. CAS No. 202668-42-6. Mole weight: 6364.10.
ODN 1826
ODN 1826 is a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist. ODN 1826 induces NO and iNOS production and enhances Apoptosis. ODN 1826 enhances immune surveillance. ODN 1826 increases aortic atherosclerotic plaque size. ODN 1826 has antitumor activity against lung cancer, glioma and melanoma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CpG 1826. CAS No. 202668-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146245.
ODN 1826 sodium (CpG 1826 sodium)
ODN 1826 sodium (CpG 1826 sodium) is a synthetic CpG oligodeoxynucleotide and agonist of TLR9 signaling pathway, that induces G1-phase arrest and apoptosis in A20 lymphoma cells while stimulating NO and iNOS production in mouse models, as part of its immunostimulatory activity. Group: Peptides. Alternative Names: CpG 1826 sodium. Pack Sizes: 1mg. Product ID: P1246.
United States; Europe
ODN 2006
ODN 2006, a ligand of choice for human TLR9, is a class B CpG ODN with a full phosphorothioate (PS) backbone. It strongly activates B cells, induces Il-6 secretion, activates the NF-kB signaling pathways, but weakly stimulates IFN-α secretion in pDCs. It is a vaccine adjuvant that can be used in breast cancer research. Alternative Names: Agatolimod; PF-3512676 free acid; CpG 7909 free acid; DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T); CpG ODN 2006; INX-2006; Type B CpG ODN 2006; CpG 2006; ODN2006; ODN-2006; ODN 2006-Type B (human). Grades: 90%. CAS No. 525625-52-9.
ODN 2007
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3'[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 455348-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150734.
ODN 2007
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 ligand that can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. Alternative Names: DNA, d(P-thio)(T-C-G-T-C-G-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T); ODN2007; ODN-2007; CpG 2007; CpG ODN 2007; ODN 2007-Type B (Bovine / Porcine). Grades: ≥95%. CAS No. 455348-63-7. Mole weight: 6852.5.
ODN 20844
ODN 20844, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a TLR7 and TLR9 (Toll-like receptor) inhibitor, and its parent is INH-ODN 2088. ODN 20844 disrupts TLR7- and TLR9-mediated immune cell immune responses. ODN 20844 sequence: 5'-TCCTGGCGc7GGGAAGT-3'[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1964506-29-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150736.
ODN 2088
ODN 2088 is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1146541-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150738.
ODN 21158
ODN 21158, a guanine-modified inhibitory oligonucleotide (INH-ODN), is a potent, non-cytotoxic inhibitor of TLR3 and TLR9, with dose-dependent inhibition of IFN-α secretion. Alternative Names: DNA, d(P-thio)(C-C-T-G-G-C-G-G-G-G); ODN-21158; ODN21158; INH-ODN 21158. CAS No. 1964506-31-7.
ODN 21595
ODN 21595, a guanine-modified inhibitory oligonucleotide (INH-ODN), is equally or significantly more potent than its parent INH-ODN 2088 to impair TLR7- and TLR9-induced responses by murine immune cells. ODN 21595 inhibits the release of IFN-α and IL-6 without cytotoxicity, and has potential for systemic lupus erythematosus (SLE) research. Alternative Names: ODN21595; ODN-21595; DNA, d(P-thio)(T-C-C-T-G-G-C-c7G-G-G-G-A-A-G-T); INH-ODN 21595. CAS No. 1964506-28-2.
ODN 2216
ODN 2216 is a type A CpG oligodeoxynucleotide vaccine adjuvant and a TLR9 agonist. ODN 2216 interacts with TLR9 in the lysosomes of CD4+ T cells and activates feedback-dependent signaling pathways. ODN 2216 induces the production of type I interferons, IL-6 and TGF-β via the IRAK4/IRF7 axis, while increasing intracellular ATP levels. ODN 2216 not only induces the differentiation of CD4+ T cells into anti-inflammatory Th3-like regulatory phenotypes to inhibit autologous proliferation, but also enhances the specific CD8+ T cell-mediated cytotoxicity against Mammaglobin-A in breast cancer cells. ODN 2216 is widely used in studies related to breast cancer and systemic lupus erythematosus[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 332437-00-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150741.
ODN 2395
ODN 2395 is a C class oligodeoxynucleotide and can be used as vaccine adjuvant. ODN 2395 is also a TLR9 agonist. ODN 2395 can be used in the research of immunological vaccines. Sequence: 5'-tcgtcgttttcggcgc:gcgccg-3' (Note: The bases are phosphorothioate; ODN 2395 contains the partial palindromic sequence cggcgc:gcgccg)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1254617-22-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150743.
ODN 24987
ODN 24987, a G-modified derivative of INH 21158, is a guanine-modified inhibitory oligonucleotide (ODN) with significantly improved inhibitory efficiency against TLR9. It impairs TLR7-mediated IL-6-release by human PBMCs. Alternative Names: DNA, d(P-thio)(C-C-T-G-G-C-c7G-G-G-G); ODN24987; ODN-24987; INH-ODN 24987. Grades: ≥95%. CAS No. 1682661-48-8. Mole weight: 3229.6.
ODN 24991
ODN 24991 is a guanine-modified inhibitory oligonucleotide (INH-ODN) used as a TLR3, TLR7, and TLR9 inhibitor. ODN 24991, a derivative of INH 21158, is significantly more efficient to impair TLR9-, TLR7-, and TLR3-mediated immune responses. Alternative Names: ODN-24991; ODN24991; DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G); INH-ODN 24991. Grades: ≥95%. CAS No. 1682661-49-9.
ODN BW006
ODN BW006 is a class B CpG ODN (oligodeoxynucleotide) that is recognized by TLR9 and has a strong immunostimulating effect. ODN BW006 can induce the proliferation of human peripheral blood mononuclear cells (PBMCs) and mouse splenocytes, as vigorously as ODN 2006, a class B prototype ODN. ODN BW006 promotes strong Th1 response. Alternative Names: ODN 684. Mole weight: 7341.
ODN D-SL01
ODN D-SL01, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist in diverse vertebrate species, namely humans, mice, rats, rabbits, pigs, and dogs. It has strong immunostimulatory activity in a variety of vertebrate species and has anticancer activity in mice with established breast cancer. Alternative Names: DNA, d(P-thio)(T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A); CpG-ODN D-SL01; D-SL01 (oligonucleotide); CpG D-SL01. Grades: ≥95%. CAS No. 1198621-84-9. Mole weight: 8340.7.
ODN D-SL03
ODN D-SL03 is a class C CpG ODN (oligodeoxynucleotide) that can induce and stimulate PBMCs to produce high levels of IFN-α. ODN D-SL03 can activate human B cells, NK cells, and mononuclear cells and up-regulate the expression of CD80, CD86, and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. It is a TLR-9 agonist used as a vaccine adjuvant. Alternative Names: DNA, d(P-thio)(T-C-G-C-G-A-A-C-G-T-T-C-G-C-C-G-C-G-T-T-C-G-A-A-C-G-C-G-G); D-SL03; CpG D-SL03; CpG-ODN D-SL03; D-SL 03. Grades: ≥95%. CAS No. 1198621-85-0. Mole weight: 9345.
ODN M362
ODN M362, a class C oligodeoxynucleotide, is a TLR-9 agonist and can be used as a vaccine adjuvant. ODN M362 induces cancer cell apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 934655-87-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150750.
ODN TTAGGG
ODN TTAGGG (ODN A151), an inhibitory oligonucleotide (ODN), is a TLR9, AIM2, and cGAS antagonist. ODN TTAGGG inhibits AIM2 inflammasome activation and cGAS activation through competition with DNA. ODN TTAGGG blocks AIM2-mediated Pyroptosis and inhibits IL-18 production. ODN TTAGGG has immunosuppressive effects and can be used in research on related autoimmune diseases such as lupus erythematosus[1][2][3]. ODN TTAGGG sequence: 5'-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-3'. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ODN A151. CAS No. 1801724-76-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150751.
Odoratisol A
Odoratisol A is a lignan isolated from the aril of Myristica fragrans Houtt. Alternative Names: 2,6-dimethoxy-4-[(2S,3S)-7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol. Grades: >98%. CAS No. 891182-93-7. Molecular formula: C21H24O5. Mole weight: 356.418.
Odoratisol A
Odoratisol A. Group: Biochemicals. Grades: Plant Grade. CAS No. 891182-93-7. Pack Sizes: 5mg. Molecular Formula: C21H24O5, Molecular Weight: 356.42. US Biological Life Sciences.
Worldwide
ODORINE
Odorine isolated from the herbs of Aglaia odorata. It inhibits the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine. Uses: Anti-carcinogenic effect. Alternative Names: (S)-2-Methyl-N-[(2R)-1-[(E)-1-oxo-3-phenyl-2-propenyl]pyrrolidin-2-yl]butanamide. Grades: 0.95. CAS No. 72755-20-5. Molecular formula: C18H24N2O2. Mole weight: 300.4.
Odorinol
Odorinol is isolated from the herbs of Aglaia odorata. It inhibits both the initiation and promotion stages of two-stage skin carcinogenesis. Alternative Names: Butanamide, 2-hydroxy-2-methyl-N-(1-(1-oxo-3-phenyl-2-propenyl)-2-pyrrolidinyl)-, (S-(R*,S*-(E)))-; (+)-Odorinol. Grades: 95.5%. CAS No. 72755-22-7. Molecular formula: C18H24N2O3. Mole weight: 316.4.
Odoroside A
Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn. Odoroside A has anti-cancer activity. Odoroside A could induce apoptosis and cell cycle arrest through ROS/p53 signaling pathway, leading to the tumor cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 12738-19-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7496.
Odorranain-A-OA1
Odorranain-A-OA1 is an antimicrobial peptide found in Odorrana andersonii (Odorrana grahami, Yunnanfu frog), and has antibacterial and antifungal activity. Alternative Names: Val-Val-Lys-Cys-Ser-Tyr-Arg-Leu-Gly-Ser-Pro-Asp-Ser-Gln-Cys-Asn (Disulfide bridge: Cys4-Cys15); OA1. Grades: ≥96%. Molecular formula: C72H116N22O25S2. Mole weight: 1753.97.
Odorranain-A-RA1 peptide precursor
Odorranain-A-RA1 peptide precursor is an antimicrobial peptide found in Odorrana andersonii (golden crossband frog), and has antimicrobial activity. Alternative Names: Pro-Met-Lys-Lys-Ser-Leu-Leu-Leu-Leu-Phe-Phe-Phe-Gly-Thr-Ile-Ser-Leu-Ser-Phe-Cys-Glu-Gln-Lys-Arg-Asp. Grades: ≥97%.