A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 209266-80-8. Pack Sizes: 25 μg. Product ID: HY-N6785A.
Okadaic Acid, a marine toxin, polyether derivative produced by dinoflagellates, is a potent, cell-permeable, specific inhibitor of PP-1 and PP-2 serine/threonine-speci?c protein phosphatases in a variety of cell types. Salt form of okadaic acid, with somewhat greater stability than the free acid when stored in organic solvents. Group: Biochemicals. Alternative Names: 9, 10-Deepithio-9, 10-dide hydroacanthifolicin, Halochondrine A. Grades: Highly Purified. CAS No. 209266-80-8. Pack Sizes: 100ug, 300ug. US Biological Life Sciences.
Worldwide
Okadaic acid, Sodium Salt (OA, Halochondrine A, Sodium Salt)
Sodium salt form of the protein phosphatase inhibitor Okadaic acid with somewhat greater stability than the free acid when stored in organic solvents. Group: Biochemicals. Grades: Highly Purified. CAS No. 209266-80-8. Pack Sizes: 100ug. US Biological Life Sciences.
Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 484-76-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6673.
Okicenone
Okicenone is originally isolated from Str. sp. KO-3599 and it has the effect of killing tumor cells. Alternative Names: 3,4-Dihydro-4,6,9-trihydroxy-8-methyl-1(2H)-anthracenone; 1(2H)-Anthracenone, 3,4-dihydro-4,6,9-trihydroxy-8-methyl-. Grades: >98 %. CAS No. 137018-54-3. Molecular formula: C15H14O4. Mole weight: 258.27.
Okilactomycin
It is originally isolated from Str. griseoflavus subsp. zamamiensis. It can resist gram-positive bacteria and inhibit leukemic cells. Alternative Names: (3R,3aR,5R,6R,8R,11aS,14S,15aS)-3,3a,5,6,7,8,9,10,11,11a,14,15-Dodecahydro-3,6,8,14-tetramethyl-16-methylene-2,17-dioxo-3,5-ethano-2H-furo[2,3-o][2]benzoxacycloundecin-13-carboxylic acid; YP-02908L-A. Grades: >98%. CAS No. 111367-04-5. Molecular formula: C24H32O6. Mole weight: 416.51.
Okra extract. Group: Others. Purity: 0.41736111. Source: Okra or Okro, is a flowering plant in the mallow family. It is valued for its edible green seed pods. The plant is cultivated in tropical, subtropical and warm temperate regions around the world. Okra extract. Cat No: EXTC-157.
Olacaftor (VX-440) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator extracted from patent US9782408. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-440. CAS No. 1897384-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112267.
Olaflur
Olaflur is used for reduction of tooth staining derived from oral care compositions comprising cationic antimicrobials. Alternative Names: luoride; Ethanol, 2,2'-((3-((2-hydroxyethyl)octadecylamino)propyl)imino)bis-, dihydrofluoride; 2,2'-((3-((2-Hydroxyethyl)octadecylamino)propyl)imino)diethanol dihydrofluoride. Grades: Active agent (Amine fluoride): 33-35%. CAS No. 6818-37-7. Molecular formula: C27H60F2N2O3. Mole weight: 498.77.
Olanexidine hydrochloride
Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 146509-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125654A.
Olanexidine Impurity1
Olanexidine Impurity1. Uses: For analytical and research use. CAS No. 109435-08-7. Molecular formula: C13H17Cl3N4. Mole weight: 335.66. Catalog: APB109435087.
Olanexidine Impurity2
Olanexidine Impurity2. Uses: For analytical and research use. Molecular formula: C13H17Cl3N4. Mole weight: 335.66. Catalog: APB12011.
Olanexidine Impurity3
Olanexidine Impurity3. Uses: For analytical and research use. CAS No. 73728-66-2. Molecular formula: C7H8Cl3N. Mole weight: 212.5. Catalog: APB73728662.
Olanexidine Impurity4
Olanexidine Impurity4. Uses: For analytical and research use. CAS No. 39226-95-4. Molecular formula: C7H8Cl4N. Mole weight: 212.5. Catalog: APB39226954.
Olanexidine Impurity5
Olanexidine Impurity5. Uses: For analytical and research use. CAS No. 5635-67-6. Molecular formula: C8H9Cl2N. Mole weight: 190.07. Catalog: APB5635676.
Olanexidine Impurity6
Olanexidine Impurity6. Uses: For analytical and research use. CAS No. 49552-34-3. Molecular formula: C7H8Cl3N. Mole weight: 212.5. Catalog: APB49552343.
Olanexidine Impurity7
Olanexidine Impurity7. Uses: For analytical and research use. CAS No. 60852-95-1. Molecular formula: C10H20N4. Mole weight: 193.3. Catalog: APB60852951.
Olanexidine Impurity9
Olanexidine Impurity9. Uses: For analytical and research use. CAS No. 218282-71-4. Molecular formula: C17H30Cl3N5O. Mole weight: 426.81. Catalog: APB218282714.
Olanzapine
Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY170053. CAS No. 132539-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14541.
Olanzapine
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H20N4S. CAS No. 132539-06-1. Prepack ID 60106881-1g. Molecular Weight 312.43. See USA prepack pricing.
Olanzapine-d3
Olanzapine-d3 (LY170053-d3) is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY170053-d3. CAS No. 786686-79-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14541S.
Olanzapine EP impurity L
Olanzapine EP impurity L. Uses: For analytical and research use. CAS No. 138564-61-1. Molecular formula: C17H22N4OS. Mole weight: 330.45. Catalog: APB138564611.
Olanzapine impurity 10
Olanzapine impurity 10. Uses: For analytical and research use. Molecular formula: C17H19N5OS. Mole weight: 341.43. Catalog: APB11361.
Olanzapine impurity 11
Olanzapine impurity 11. Uses: For analytical and research use. Molecular formula: C17H20N4O2S. Mole weight: 344.43. Catalog: APB11362.
Olanzapine impurity 5
Olanzapine impurity 5. Uses: For analytical and research use. CAS No. 2586222-75-2. Molecular formula: C12H10N2O2S. Mole weight: 246.28. Catalog: APB2586222752.
Olanzapine impurity 6
Olanzapine impurity 6. Uses: For analytical and research use. CAS No. 1313411-74-3. Molecular formula: C24H18N4O2S2. Mole weight: 458.55. Catalog: APB1313411743.
Olanzapine impurity 7
Olanzapine impurity 7. Uses: For analytical and research use. CAS No. 2518067-58-6. Molecular formula: C17H20N4OS. Mole weight: 328.43. Catalog: APB2518067586.
Olanzapine impurity SA
Olanzapine impurity SA. Uses: For analytical and research use. Alternative Names: 2-amino-5-methylthiophene-3-carbonitrile. CAS No. 138564-58-6. Molecular formula: C6H6N2S. Mole weight: 138.19. Catalog: APB138564586.
Olanzapine Related Compound A
Olanzapine Related Compound A. Uses: For analytical and research use. CAS No. 138564-59-7. Mole weight: 259.28. Catalog: AP138564597.
Olanzapine thiolactam
Olanzapine thiolactam (compound 2) is an impurity of Olanzapine[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1017241-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z4467.
Olaparib
500mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H23FN4O3. CAS No. 763113-22-0. Prepack ID 90027882-500mg. Molecular Weight 434.46. See USA prepack pricing.
Olaparib
Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.PARP1 acts as a critical molecule in the repair of DNA single-strand breaks (SSBs) and plays an important role in maintaining DNA integrity. de Murcia, J., et al. "Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells." Proc. Natl. Acad. Sci. USA 94: 7303-7307 (1997).PARP inhibitors inhibit PARP1 during S-phase and.num drugs." Proc. Natl. Acad. Sci. USA 105: 17079-17084 (2008).Long-term treatment with olaparib caused the development of drug resistance, which was induced by up-regulation of Abcb1a/b genes encoding P-glycoprotein efflux pumps. The resistance to. Group: Biochemicals. Alternative Names: 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; AZD-2281; KU 0059436; KU-59436; 1- (Cyclopropylcarbonyl) -4- [5- [ (3, 4-dihydro-4-oxo-1-phthalazinyl) methyl] -2-fluorobenzoyl] piperazine. Grades: Highly Purified. CAS No. 763113-22-0. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 434.46. US Biological Life Sciences.
Worldwide
Olaparib
Olaparib, also known as AZD-2281 or KU-59436, is a small-molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Alternative Names: AZD2281; AZD-2281; AZD 2281; KU59436; KU-59436; KU 59436; KU0059436; KU-0059436; KU 0059436; Olaparib. trade name Lynparza; 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one. Grades: >98%. CAS No. 763113-22-0. Molecular formula: C24H23FN4O3. Mole weight: 434.471.
Olaparib
Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator. Olaparib cannot cross the intact blood-brain barrier (BBB)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD2281; KU0059436. CAS No. 763113-22-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-10162.
Olaparib-d4-1
Olaparib-d4-1 (AZD2281-d4-1) is the deuterium labeled Olaparib (HY-10162). Olaparib is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD2281-d4-1; KU0059436-d4-1. CAS No. 2143107-55-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-10162S3.
Olaparib-d5
Olaparib D5 is a deuterium labeled Olaparib. Olaparib is a potent and oral inhibitor of PARP. Category: Active pharmaceutical ingredients. CAS No. 2143107-56-4. Product ID: API2143107564. Molecular formula: C24H23FN4O3. Mole weight: 439.49.
Olaparib Impurity 1
Olaparib Impurity 1. Uses: For analytical and research use. CAS No. 763113-06-0. Molecular formula: C24H24N4O3. Mole weight: 416.48. Catalog: APB763113060.
Olaparib Impurity 1
Olaparib Impurity 1. Uses: For analytical and research use. Alternative Names: 3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile. Molecular formula: C16H11N3O. Mole weight: 261.28. Catalog: APB02135.
Olaparib Impurity 10
Olaparib Impurity 10. Uses: For analytical and research use. CAS No. 2415448-60-9. Molecular formula: C18H16FN3O2. Mole weight: 325.34. Catalog: APB2415448609.
Olaparib Impurity 11
Olaparib Impurity 11. Uses: For analytical and research use. CAS No. 2630919-53-6. Molecular formula: C16H10FNO3. Mole weight: 283.26. Catalog: APB2630919536.
Olaparib Impurity 12
Olaparib Impurity 12. Uses: For analytical and research use. CAS No. 2250242-62-5. Molecular formula: C36H28F2N6O4. Mole weight: 646.65. Catalog: APB2250242625.
Olaparib Impurity 13
Olaparib Impurity 13. Uses: For analytical and research use. CAS No. 2250243-17-3. Molecular formula: C24H25FN4O3. Mole weight: 436.49. Catalog: APB2250243173.
Olaparib Impurity 14
Olaparib Impurity 14. Uses: For analytical and research use. CAS No. 420846-72-6. Molecular formula: C16H12N2O3. Mole weight: 280.28. Catalog: APB420846726.
Olaparib Impurity 15
Olaparib Impurity 15. Uses: For analytical and research use. CAS No. 763111-47-3. Molecular formula: C20H19FN4O2. Mole weight: 366.39. Catalog: APB763111473.
Olaparib Impurity 17
Olaparib Impurity 17. Uses: For analytical and research use. Molecular formula: C16H12FNO4. Mole weight: 301.27. Catalog: APB08849.
Olaparib Impurity 18
Olaparib Impurity 18. Uses: For analytical and research use. CAS No. 164149-28-4. Molecular formula: C8H4FNO2. Mole weight: 165.12. Catalog: APB164149284.
Olaparib Impurity 2
Olaparib Impurity 2. Uses: For analytical and research use. CAS No. 2409514-28-7. Molecular formula: C16H11FO5. Mole weight: 302.26. Catalog: APB2409514287.
Olaparib Impurity 25
Olaparib Impurity 25. Uses: For analytical and research use. CAS No. 1423030-11-8. Molecular formula: C16H9FO4. Mole weight: 284.24. Catalog: APB1423030118.
Olaparib Impurity 3
Olaparib Impurity 3. Uses: For analytical and research use. CAS No. 61260-15-9. Molecular formula: C10H11O5P. Mole weight: 242.17. Catalog: APB61260159.
Olaparib Impurity 30
Olaparib Impurity 30. Uses: For analytical and research use. CAS No. 1460272-52-9. Molecular formula: C24H21FN4O4. Mole weight: 448.45. Catalog: APB1460272529.
Olaparib Impurity 31
Olaparib Impurity 31. Uses: For analytical and research use. CAS No. 458535-34-7. Molecular formula: C12H18N2O2. Mole weight: 222.29. Catalog: APB458535347.
Olaparib Impurity 33
Olaparib Impurity 33. Uses: For analytical and research use. CAS No. 550363-85-4. Molecular formula: C8H5FO3. Mole weight: 168.12. Catalog: APB550363854.
Olaparib Impurity 38
Olaparib Impurity 38. Uses: For analytical and research use. CAS No. 632-22-4. Molecular formula: C5H12N2O. Mole weight: 116.16. Catalog: APB632224.
Olaparib Impurity 39
Olaparib Impurity 39. Uses: For analytical and research use. CAS No. 59878-57-8. Molecular formula: C8H14N2O. Mole weight: 154.21. Catalog: APB59878578.
Olaparib Impurity 4
Olaparib Impurity 4. Uses: For analytical and research use. CAS No. 1021298-68-9. Molecular formula: C16H10FN3O. Mole weight: 279.27. Catalog: APB1021298689.
Olaparib Impurity 43
Olaparib Impurity 43. Uses: For analytical and research use. CAS No. 64579-56-2. Molecular formula: C10H18N2O. Mole weight: 182.27. Catalog: APB64579562.
Olaparib Impurity 45
Olaparib Impurity 45. Uses: For analytical and research use. Alternative Names: 2-methoxy-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile. Molecular formula: C17H13N3O2. Mole weight: 291.30. Catalog: APB02136.
Olaparib Impurity 46
Olaparib Impurity 46. Uses: For analytical and research use. Alternative Names: 4-((3-amino-1H-indazol-5-yl)methyl)phthalazin-1(2H)-one. Molecular formula: C16H13N5O. Mole weight: 291.31. Catalog: APB02133.
Olaparib Impurity 5
Olaparib Impurity 5. Uses: For analytical and research use. CAS No. 16859-59-9. Molecular formula: C8H6O3. Mole weight: 150.13. Catalog: APB16859599.
Olaparib Impurity 55
Olaparib Impurity 55. Uses: For analytical and research use. CAS No. 763113-20-8. Molecular formula: C23H23FN4O3. Mole weight: 422.46. Catalog: APB763113208.
Olaparib Impurity 56
Olaparib Impurity 56. Uses: For analytical and research use. CAS No. 1956324-57-4. Molecular formula: C17H14N2O4. Mole weight: 310.31. Catalog: APB1956324574.
Olaparib Impurity 58
Olaparib Impurity 58. Uses: For analytical and research use. CAS No. 848136-41-4. Molecular formula: C22H21FN4O3. Mole weight: 408.43. Catalog: APB848136414.
Olaparib Impurity 6
Olaparib Impurity 6. Uses: For analytical and research use. CAS No. 179897-89-3. Molecular formula: C7H3BrFN. Mole weight: 200.01. Catalog: APB179897893.
Olaparib Impurity 62
Olaparib Impurity 62. Uses: For analytical and research use. CAS No. 76816-54-1. Molecular formula: C7H14N2O. Mole weight: 142.2. Catalog: APB76816541.
Olaparib Impurity 63
Olaparib Impurity 63. Uses: For analytical and research use. CAS No. 71260-16-7. Molecular formula: C8H16N2O. Mole weight: 156.23. Catalog: APB71260167.
Olaparib Impurity 64
Olaparib Impurity 64. Uses: For analytical and research use. CAS No. 155295-47-9. Molecular formula: C9H18N2O. Mole weight: 170.26. Catalog: APB155295479.