A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
o-Nitrophenyl 2,3,4-Tri-O-acetyl-β-D-galactopyranoside is a chemical compound used in biomedicine for the detection of β-galactosidase activity. It acts as a substrate for this enzyme and produces a yellow-colored product upon hydrolysis. This compound is particularly useful in studying gene expression and protein function, as well as in the diagnosis. Molecular formula: C18H21NO11. Mole weight: 427.36.
O-Nitrophenyl b-D-cellobioside
O-Nitrophenyl b-D-cellobioside. Group: Biochemicals. Grades: Reagent Grade. CAS No. 70867-33-3. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
o-Nitrophenyl Benzyl Ether
o-Nitrophenyl Benzyl Ether. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
o-Nitro Toluene
o-Nitro Toluene.
Onjisaponin B
Onjisaponin B is extracted from the roots of Polygala tenuifolia. It was able to induce autophagy and accelerate both the removal of mutant huntingtin and A53T α-synuclein, which are highly associated with Huntington disease and Parkinson disease, respectively. It induces autophagy via the AMPK-mTOR signaling pathway. It increased the NGF level and may have potential therapeutic effects for the treatment of Alzheimer disease patients. Alternative Names: Senegin III; Sinegin 3. Grades: >98%. CAS No. 35906-36-6. Molecular formula: C75H112O35. Mole weight: 1573.7.
Onjisaponin B
Onjisaponin B. Group: Biochemicals. CAS No. 35906-36-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Onjisaponin Z
Onjisaponin Z. Group: Biochemicals. Grades: Plant Grade. CAS No. 1078708-72-1. Pack Sizes: 5mg. Molecular Formula: C71H106O32, Molecular Weight: 1471.6. US Biological Life Sciences.
Worldwide
Onjisaponin Z
Onjisaponin Z is a triterpenoid isolated from Polygalae radix. Grades: 0.98. CAS No. 1078708-72-1. Molecular formula: C71H106O32. Mole weight: 1471.59.
Onjisaponin Z
Onjisaponin Z is a natural product isolated from Radix Polygalae. Uses: Scientific research. Category: Natural products. CAS No. 1078708-72-1. Pack Sizes: 5 mg. Product ID: HY-N4325.
O,N,N'-Triisopropylisourea
O,N,N'-Triisopropylisourea. Group: Biochemicals. Alternative Names: N, N'-Diisopropyl carbamimidic Acid Isopropyl Ester; Isopropyl N, N'-Diisopropyl carbamimidate. Grades: Highly Purified. CAS No. 63460-32-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
ONO-0740556
ONO-0740556 is a potent Gi-coupled human lysophosphatidic acid receptor 1 (LPA1) agonist with an EC50 value of 0.26 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250210-69-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150204.
ONO 1301
ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO-AP 500-02. CAS No. 176391-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106961.
ONO 2506
ONO 2506. Group: Biochemicals. Grades: Purified. CAS No. 185517-21-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ono-4007(free acid)
Ono-4007(free acid). CAS No. 111250-67-0. Product ID: ACM111250670. Molecular formula: C50H79NO12S. Mole weight: 918.23. Alfa Chemistry - ISO 9001:32057 Certified.
ONO-4059
ONO-4059, a BTK inhibitor, has been found to have potential effect against sorts of malignancies by influencing the B-cell development. It is currently under Phase II trail to study its effect against Chronic lymphocytic leukaemia. IC50: 2.2 nM. Alternative Names: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one; ONO-4059; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. Grades: 98%. CAS No. 1351636-18-4. Molecular formula: C25H22N6O3. Mole weight: 454.48.
ONO-4059 (hydrochloride)
ONO-4059 (hydrochloride) is the hydrochloride salt form of Tirabrutinib. ONO-4059 is a highly selective, orally bioavailable BTK inhibitor (IC50= 2.2 nM) and demonstrated therapeutic efficacy in a mouse arthritis model. Alternative Names: (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one hydrochloride; ONO-4059 HCl; ONO4059; ONO 4059; ONO-4059; GS 4059; GS-4059; GS4059; ONO-WG-307; Tirabrutinib. CAS No. 1439901-97-9. Molecular formula: C25H23ClN6O3. Mole weight: 490.95.
ONO 4817
ONO 4817. Group: Biochemicals. Grades: Purified. CAS No. 223472-31-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ONO-7300243
ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 638132-34-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100882.
ONO-7475
ONO-7475 is an Axl/Mer inhibitor that has been shown to inhibit the phosphorylation of AXL and Mer, and to suppress the growth of acute myeloid leukemia with FLT3 mutations (26, 27) and solid tumors. Alternative Names: ONO 7475; ONO7475. Grades: >98%. CAS No. 1646839-59-9. Molecular formula: C32H26N4O6. Mole weight: 562.6.
ONO-8430506
ONO-8430506 is an orally bioavailable and potent autotaxin (ATX)/ENPP2 inhibitor with the IC90 of 100 nM for ATX activity in mouse plasma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354805-08-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145344.
ONO-8713
ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 459411-08-6. Pack Sizes: 1 mg. Product ID: HY-142868.
ONO-9780307
ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 856691-44-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117444.
ONO-AE 248
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 211230-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12184.
ONO AE3 208
ONO AE3 208. Group: Biochemicals. Grades: Purified. CAS No. 402473-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ONO-AE3-208
ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM. ONO-AE3-208 shows less potently affects EP3, FP, and TP receptors (Ki of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AE 3-208. CAS No. 402473-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50901.
ONO-AE3-208
ONO-AE3-208 is an EP4 antagonist (Ki values are 1.3, 30, 790 and 2400 nM for EP4, EP3, FP and TP receptors respectively), which less potently affects EP3, FP, and TP receptors. Uses: An ep4 antagonist. Alternative Names: ONO-AE3-208; ONO-AE-3-208; ONO-AE 3-208; AE 3-208; AE-3-208; AE3-208; ONO AE3 208 4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid; 4-[4-cyano-2-[2-(4-fluoronaphthalen-1-yl)propanoylamino]phenyl]butanoic acid. Grades: ≥98%. CAS No. 402473-54-5. Molecular formula: C24H21FN2O3. Mole weight: 404.43.
Ononetin, a natural deoxybenzoin, is a potent and selective TRPM3 channel blocker with an IC50 of 0.3 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 487-49-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108451.
Ononin
Ononin is an isoflavonoid, is an additional growth inhibitor in soils associated with the weed, Pluchea lanceolata. It may act by inducing erythropoietin expression. It can inhibit the growth of pathogen. It play an important role in human nutrition as health promoting natural chemicals and are established to be the beneficial components. Uses: Inhibit the growth of pathogen. Alternative Names: Fomononetin; Formononetin 7-O-β-D-glucopyranoside; Ononoside. Grades: >98%. CAS No. 486-62-4. Molecular formula: C22H22O9. Mole weight: 430.4.
Ononin
Ononin. Group: Biochemicals. CAS No. 486-62-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ONO-TR-772
ONO-TR-772 (VU6018042) is a selective TREK inhibitor (IC50: 15 nM). ONO-TR-772 enhances recognition memory in the MK-801-stimulated NOR mouse model. ONO-TR-772 can be used in the study of diseases related to cognitive impairment[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU6018042. CAS No. 2640847-32-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176411.
ONPG
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Nitrophenyl β-D-galactopyranoside. CAS No. 369-07-3. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-15926.
Onradivir
Onradivir (ZSP1273) is an orally active antiviral agent targeting influenza A virus RNA polymerase PB2 subunit with an IC50 of 0.562 nM. Onradivir inhibits cap binding to influenza A virus RNA polymerase PB2 subunit, suppresses viral replication, reduces viral titres and RNA loads, and inhibits influenza A virus infection. Onradivir maintains high survival rates in influenza A virus-infected mice, and reduces influenza A virus titers in a murine model. Onradivir can be used for the research of influenza A virus infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZSP1273. CAS No. 2200336-20-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145586.
Coupling reagent for synthesis of peptide and the formation of other amides. Alternative Names: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate; HSTU; O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium hexafluorophosphate; AmbotzRL-1039; hexafluorophosphate. Grades: ≥ 99.5% (HPLC). CAS No. 265651-18-1. Molecular formula: C9H16F6N3O3P. Mole weight: 359.21.
O-[(N-Succinimidyl)succinyl-aminoethyl]-O'-methylpolyethylene glycol 2'000. CAS No. 92451-00-8.
ONT-993
ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 μM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AR 00440993. CAS No. 937263-81-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-151239.
Ontamalimab
Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SHP647. CAS No. 2098790-40-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99411.
Ontorpacept
Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TTI-621. CAS No. 2131089-46-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99777.
Ontunisertib
Ontunisertib (AGMB-129) is an orally active and selective gastrointestinal-restricted ALK5 (TGFβR1) inhibitor. Ontunisertib blocks signalling of the pro-fibrotic TGFβ pathway. Ontunisertib can be used for the research of fibrostenotic Crohns disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AGMB-129. CAS No. 2647949-48-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168990.
Ontuxizumab
Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MORAb-004. CAS No. 946415-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99778.
Onvansertib
NMS-1286937 is a potent, selective and orally available PLK1 inhibitor, with an IC50 of 2 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NMS-1286937; NMS-P937. CAS No. 1034616-18-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15828.
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-61610588; CI-8993; VSTB112. CAS No. 1969313-51-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99040.
ONX-0914
ONX-0914 (PR-957) is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 μM). ONX-0914 reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PR-957. CAS No. 960374-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13207.
O,O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol. CAS No. 186020-53-1.
O, O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]Polyethylene glycol
O,O'-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is a cross-linking reagent. Alternative Names: α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate). CAS No. 186020-53-1. Mole weight: average Mn 10,000.
O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid
O,O-Di-2-Naphthalenyl Ester Carbonothioic Acid (Tolnaftate EP Impurity B) is a Tolnaftate impurity. Tolnaftate (T535400) functions as an antifungal agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 127084-74-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C21H14O2S. US Biological Life Sciences.
Worldwide
O,O'-Di-2-pyridyl Thiocarbonate
O,O'-Di-2-pyridyl Thiocarbonate. Group: Biochemicals. Alternative Names: Di-2-Pyridyl Thionocarbonate; Thiocarbonic Acid O,O'-Di-2-pyridyl Ester. Grades: Highly Purified. CAS No. 96989-50-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.