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Palonosetron Related Compound D. Uses: For analytical and research use. CAS No. 135755-51-0. Mole weight: 332.87. Catalog: AP135755510.
Palonosetron Related Compound E
Palonosetron Related Compound E. Uses: For analytical and research use. CAS No. 135729-55-4. Mole weight: 330.85. Catalog: AP135729554.
Palonosetron USP Impurity B
Palonosetron USP Impurity B. Uses: For analytical and research use. CAS No. 1021456-82-5. Molecular formula: C19H22N2O2. Mole weight: 310.4. Catalog: APB1021456825.
Palonosetron USP Impurity E
Palonosetron USP Impurity E. Uses: For analytical and research use. CAS No. 135729-55-4. Molecular formula: C19H23ClN2O. Mole weight: 330.86. Catalog: APB135729554.
Palosuran
Palosuran (ACT-058362) is a potent, selective, and orally active antagonist of urotensin II receptor, with an IC50 of 3.6 nM for CHO cell membranes expressing human recombinant receptors. Palosuran can improves pancreatic and renal function in diabetic rats[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACT-058362. CAS No. 540769-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10655.
Palosuran
Palosuran is a new Urotensin-II receptor antagonist (IC50=3.6±0.2 nM). Uses: Urotensin-ii receptor antagonist. Alternative Names: 1-[2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl]-3-(2-methylquinolin-4-yl)urea;ACT-058362; ACT058362; ACT 058362. Grades: ≥95%. CAS No. 540769-28-6. Molecular formula: C25H30N4O2. Mole weight: 418.54.
Palovarotene
Palovarotene is a nuclear retinoic acid receptor γ (RAR-γ) agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R 667; Ro 3300074. CAS No. 410528-02-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14799.
P-alpha
It is a synthetic peptide and cell-penetrating peptide. Alternative Names: H-Gly-Ala-Leu-Phe-Leu-Ala-Phe-Leu-Ala-Ala-Ala-Leu-Ser-Leu-Met-Gly-Leu-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Arg-Val-OH. Molecular formula: C140H230N38O31S. Mole weight: 2973.68.
PAL resin is useful for the synthesis of peptide amides using Fmoc strategy. Cleavage has been performed with 50% TFA in CH2Cl2 or 95% aqueous TFA. Scavengers may be required. Alternative Names: H2NCH2-Ph(OCH3)2-O-CH2-polymer; 4-Alkoxy-2,6-dimethoxybenzylamine resin.
Pal-RFK(tri-peptide)
Pal-RFK(tri-peptide). Product ID: ACMA00011776. Alfa Chemistry - ISO 9001:32057 Certified.
Pal-tetrapeptide-3/7
Pal-tetrapeptide-3/7. Alternative Names: Palmitoyl tetrapeptide-7. CAS No. 221227-05-0. Purity: 0.95. Product ID: CI-BP-0004. Molecular formula: C34H62N8O7. Mole weight: 694.91 g/mol. IUPAC Name: (2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Paltimatrectinib
Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PBI-200; PPI-5278. CAS No. 2353522-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145587.
Paludosic acid
Paludosic acid. Alternative Names: o-Anisic acid, 4-hydroxy-6-propyl-, 3-ester with 2,3,4-trihydroxy-6-pentylbenzoic acid (8CI); 2,4-Dihydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-6-pentylbenzoic acid; 4-O-Demethylmerochloropheic acid; Benzoic acid, 2,4-dihydroxy-3-[(4-hydroxy-2-methoxy-6-propylbenzoyl)oxy]-6-pentyl-. CAS No. 19833-81-9. Molecular formula: C23H28O8. Mole weight: 432.46.
Palupiprant
Palupiprant (E7046) is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM. Palupiprant exhibits anti-tumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7046. CAS No. 1369489-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103088.
Palustric acid
Palustric acid is a bioactive substance found in nature. Extensive investigations have elucidated its remarkable anti-inflammatory attributes, rendering it an auspicious contender for studying the effects of inflammatory ailments like arthritis. Alternative Names: PALUSTRIC ACID; 1945-53-5; NSC 148945; PALUSTRICACID; A2QAG30V3T; Podocarpa-8,13-dien-15-oic acid, 13-isopropyl-; C12077; AC1L9EWT; UNII-A2QAG30V3T; Palustrinsaure; Palustric; NSC-148945; SureCN151741; PALUSTRIC ACID [MI]; SCHEMBL151741; CHEBI:29660; DTXSID90858759; MLBYBBUZURKHAW-MISYRCLQSA-N; AKOS040757142; (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,5,6,9,10,10a-octahydrophenanthrene-1-carboxylic acid; 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,5,6,9,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R-(1a, 4ab,10aa))-; HY-133593; CS-0128314; Q27110213; (1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-2,3,4,5,6,9,10,10a-octahydrophenanthrene-1-carboxylic acid; 1-PHENANTHRENECARBOXYLIC ACID, 1,2,3,4,4A,5,6,9,10,10A-DECAHYDRO-1,4A-DIMETHYL-7-(1-METHYLETHYL)-, (1R,4AS,10AR)-. Grades: 95%. CAS No. 1945-53-5. Molecular formula: C20H30O2. Mole weight: 302.45.
Palustric acid
Palustric acid. Alternative Names: Abieta-8,13-dien-18-oic acid. CAS No. 1945-53-5. Purity: >95.0%. Product ID: FFC-AR-1945535. Molecular formula: C20H30O2. Mole weight: 302.45. IUPAC Name: (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,5,6,9,10,10a-octahydrophenanthrene-1-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Palustrin-1a
Palustrin-1a is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli. Alternative Names: Recombinant Rana palustris Palustrin-1a. Grades: >85%. Molecular formula: C144H238N38O35S3. Mole weight: 3157.85.
Palustrin-1b
Palustrin-1b is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli (MIC=8 μM). Alternative Names: Recombinant Rana palustris Palustrin-1b; Ala-Leu-Phe-Ser-Ile-Leu-Arg-Gly-Leu-Lys-Lys-Leu-Gly-Asn-Met-Gly-Gln-Ala-Phe-Val-Asn-Cys-Lys-Ile-Tyr-Lys-Lys-Cys (Disulfide bridge: Cys22-Cys28). Grades: ≥97%. Molecular formula: C143H237N39O34S3. Mole weight: 3142.89.
Palustrin-1c
Palustrin-1c is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antimicrobial activity against gram-negative bacterium E.coli (MIC=28 μM). Alternative Names: Recombinant Rana palustris Palustrin-1c; Ala-Leu-Ser-Ile-Leu-Arg-Gly-Leu-Glu-Lys-Leu-Ala-Lys-Met-Gly-Ile-Ala-Leu-Thr-Asn-Cys-Lys-Ala-Thr-Lys-Lys-Cys (Disulfide bridge: Cys21-Cys27). Grades: ≥95%. Molecular formula: C125H226N36O34S3. Mole weight: 2873.58.
Palustrin-1d
Palustrin-1d is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli (MIC=28 μM). Alternative Names: Recombinant Rana palustris Palustrin-1d; Ala-Leu-Ser-Ile-Leu-Lys-Gly-Leu-Glu-Lys-Leu-Ala-Lys-Met-Gly-Ile-Ala-Leu-Thr-Asn-Cys-Lys-Ala-Thr-Lys-Lys-Cys (Disulfide bridge: Cys21-Cys27). Grades: ≥95%. Molecular formula: C125H226N34O34S3. Mole weight: 2845.57.
Palustrin-2a
Palustrin-2a is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli. Alternative Names: Recombinant Rana palustris Palustrin-2a. Grades: >85%. Molecular formula: C137H233N41O42S2. Mole weight: 3190.74.
Palustrin-2AJ1
Palustrin-2AJ1 is an antimicrobial peptide found in Amolops jingdongensis (Chinese torrent frog), and has broad-spectrum antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Alternative Names: PL2AJ1; Recombinant Amolops jingdongensis Palustrin-2AJ1; Gly-Phe-Met-Asp-Thr-Ala-Lys-Asn-Val-Ala-Lys-Asn-Val-Ala-Val-Thr-Leu-Ile-Asp-Lys-Leu-Arg-Cys-Lys-Val-Thr-Gly-Gly-Cys (Disulfide bridge: Cys23-Cys29). Grades: ≥98%. Molecular formula: C131H224N38O39S3. Mole weight: 3051.64.
Palustrin-2AJ2
Palustrin-2AJ2 is an antimicrobial peptide found in Amolops jingdongensis (Chinese torrent frog), and has broad-spectrum antibacterial activity against a range of Gram-positive and Gram-negative bacteria. Alternative Names: PL2AJ2; Recombinant Amolops jingdongensis Palustrin-2AJ2; Gly-Phe-Met-Asp-Thr-Ala-Lys-Gln-Val-Ala-Lys-Asn-Val-Ala-Val-Thr-Leu-Ile-Asp-Lys-Leu-Arg-Cys-Lys-Val-Thr-Gly-Gly-Cys (Disulfide bridge: Cys23-Cys29). Grades: ≥97%. Molecular formula: C132H226N38O39S3. Mole weight: 3065.67.
Palustrin-2b
Palustrin-2b is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli (MIC=78 μM). Alternative Names: Gly-Phe-Phe-Ser-Thr-Val-Lys-Asn-Leu-Ala-Thr-Asn-Val-Ala-Gly-Thr-Val-Ile-Asp-Thr-Leu-Lys-Cys-Lys-Val-Thr-Gly-Gly-Cys-Arg-Ser (Disulfide bridge: Cys23-Cys29); Recombinant Rana palustris Palustrin-2b. Grades: ≥97%. Molecular formula: C138H229N39O43S2. Mole weight: 3186.70.
Palustrin-2c
Palustrin-2c is an antimicrobial peptide found in Rana palustris (Pickerel frog, Lithobates palustris), and has antibacterial activity against gram-negative bacterium E.coli (MIC=120 μM). Alternative Names: Recombinant Rana palustris Palustrin-2c; Gly-Phe-Leu-Ser-Thr-Val-Lys-Asn-Leu-Ala-Thr-Asn-Val-Ala-Gly-Thr-Val-Ile-Asp-Thr-Leu-Lys-Cys-Lys-Val-Thr-Gly-Gly-Cys-Arg-Ser (Disulfide bridge: Cys23-Cys29). Grades: ≥96%. Molecular formula: C135H231N39O43S2. Mole weight: 3152.68.
Palustrin-2CE
Palustrin-2CE is an antimicrobial peptide found in Rana chensinensis (Chinese brown frog), and has antimicrobial activity against B.subtilis, P.aeruginosa, E.coli (MIC=5-30 μM) and S.aureus (MIC=90-100 μM), including resistant E.coli and S.aureus strains. Alternative Names: Gly-Leu-Trp-Asp-Ser-Ile-Lys-Asn-Phe-Gly-Lys-Thr-Ile-Ala-Leu-Asn-Val-Met-Asp-Lys-Ile-Lys-Cys-Lys-Ile-Gly-Gly-Gly-Cys-Pro-Pro (Disulfide bridge: Cys23-Cys29). Grades: ≥97%. Molecular formula: C148H241N39O40S3. Mole weight: 3302.97.
Palustrin-2CG1
Palustrin-2CG1 is an antimicrobial peptide found in Amolops chunganensis (Chungan torrent frog, Hylorana chunganensis), and has antimicrobial activity against a variety of Gram-positive and some Gram-negative bacterial strains. It has antifungal activity against slime mold isolate. It has hemolytic activity against human erythrocytes. Alternative Names: Gly-Leu-Trp-Asn-Thr-Ile-Lys-Glu-Ala-Gly-Lys-Lys-Phe-Ala-Ile-Asn-Val-Leu-Asp-Lys-Ile-Arg-Cys-Gly-Ile-Ala-Gly-Gly-Cys-Lys-Thr (Disulfide bridge: Cys23-Cys29). Grades: ≥97%. Molecular formula: C147H244N42O40S2. Mole weight: 3303.94.
Palustrin-2ISb precursor protein
Palustrin-2ISb precursor protein is an antimicrobial peptide found in Odorrana ishikawae (Ishikawa frog), and has antibacterial and antifungal activity. Alternative Names: Leu-Trp-Asn-Ser-Ile-Lys-Ile-Ala-Gly-Lys-Lys-Leu-Phe-Val-Asn-Val-Leu-Asp-Lys-Ile-Arg-Cys-Lys-Val-Ala-Gly-Gly-Cys-Lys-Thr-Ser-Pro-Asp-Val-Glu. Grades: ≥97%. Molecular formula: C172H287N47O47S2. Mole weight: 3829.59.
Palustrin-2ISc
Palustrin-2ISc is an antimicrobial peptide found in Odorrana ishikawae (Ishikawa's frog, Rana ishikawae), and has antimicrobial activity against gram-negative bacterium Escherichia coli (MIC=100 μM) and gram-positive bacterium Staphylococcus aureus (MIC=25 μM), Bacillus subtilis (MIC=12.5 μM). Alternative Names: Gly-Phe-Met-Asp-Thr-Ala-Lys-Asn-Val-Ala-Lys-Asn-Val-Ala-Ala-Thr-Leu-Leu-Asp-Lys-Leu-Lys-Cys-Lys-Ile-Thr-Gly-Gly-Cys (Disulfide bridge: Cys23-Cys29). Grades: ≥97%. Molecular formula: C130H222N36O39S3. Mole weight: 3009.60.
Palustrin-2LTa
Palustrin-2LTa is an antimicrobial peptide found in the broad-folded frog, Hylarana latouchii, China, Asia, and has anti-gram-positive bacteria (Staphylococcus aureus ATCC2592 (MIC=1.7 μM), Bacillus licheniformis X39 (MIC=14 μM), Psychrobacter faecalis X29 (MIC=1.7 μM)) and gram-negative bacteria activity. Alternative Names: palustrin-2; Ser-Leu-Trp-Glu-Asn-Phe-Lys-Asn-Ala-Gly-Lys-Gln-Phe-Ile-Leu-Asn-Ile-Leu-Asp-Lys-Ile-Arg-Cys-Arg-Val-Ala-Gly-Gly-Cys-Arg-Thr (Disulfide bridge: Cys23-Cys29). Grades: ≥95%. Molecular formula: C157H254N48O42S2. Mole weight: 3550.17.
Palustrin-2SIb
Palustrin-2SIb is an antimicrobial peptide found in Odorrana ishikawae, and has antibacterial and antifungal activity. Alternative Names: Gly-Leu-Trp-Asn-Ser-Ile-Lys-Ile-Ala-Gly-Lys-Lys-Leu-Phe-Val-Asn-Val-Leu-Asp-Lys-Ile-Arg-Cys-Lys-Val-Ala-Gly-Gly-Cys-Lys-Thr-Ser-Pro-Asp-Val-Glu (Disulfide bridge: Cys23-Cys29). Grades: ≥96%. Molecular formula: C174H290N48O48S2. Mole weight: 3886.64.
Palustrin-3a
Palustrin-3a is an antimicrobial peptide found in North America, Rana palustris (Pickerel frog, Lithobates palustris), and has activity against gram-negative bacteria Escherichia coli (MIC=1 μM). Alternative Names: Recombinant Rana palustris Palustrin-3a; L-Cysteine, glycyl-L-isoleucyl-L-phenylalanyl-L-prolyl-L-lysyl-L-isoleucyl-L-isoleucylglycyl-L-lysylglycyl-L-isoleucyl-L-lysyl-L-threonylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-isoleucyl-L-lysyl-L-seryl-L-leucyl-L-valyl-L-lysylglycyl-L-valylglycyl-L-methionyl-L-lysyl-L-valyl-L-phenylalanyl-L-lysyl-L-alanylglycyl-L-leucyl-L-asparaginyl-L-asparaginyl-L-isoleucylglycyl-L-asparaginyl-L-threonylglycyl-L-cysteinyl-L-asparaginyl-L-α-glutamyl-L-α-aspartyl-L-α-glutamyl-, cyclic(43→48)-disulfide. Grades: >85%. CAS No. 326603-06-9. Molecular formula: C218H366N60O63S3. Mole weight: 4931.86.
Palustrin-3AR
Palustrin-3AR is an antimicrobial peptide found in Rana areolata (North American crawfish frog), and has antibacterial activity. Alternative Names: H-Gly-Ile-Phe-Pro-Lys-Ile-Ile-Gly-Lys-Gly-Ile-Val-Asn-Gly-Ile-Lys-Ser-Leu-Ala-Lys-Gly-Val-Gly-Met-Lys-Val-Phe-Lys-Ala-Gly-Leu-Asn-Asn-Ile-Gly-Asn-Thr-Gly-Cys-Asn-Asn-Arg-Asp-Glu-Cys-OH (Disulfide bridge: Cys39-Cys45); glycyl-L-isoleucyl-L-phenylalanyl-L-prolyl-L-lysyl-L-isoleucyl-L-isoleucyl-glycyl-L-lysyl-glycyl-L-isoleucyl-L-valyl-L-asparagyl-glycyl-L-isoleucyl-L-lysyl-L-seryl-L-leucyl-L-alanyl-L-lysyl-glycyl-L-valyl-glycyl-L-methionyl-L-lysyl-L-valyl-L-phenylalanyl-L-lysyl-L-alanyl-glycyl-L-leucyl-L-asparagyl-L-asparagyl-L-isoleucyl-glycyl-L-asparagyl-L-threonyl-glycyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-arginyl-L-alpha-aspartyl-L-alpha-glutamyl-L-cysteine cyclic(39→45)-disulfide. Grades: >98%. Molecular formula: C203H340N60O58S3. Mole weight: 4645.49.
Palustrin-3b
Palustrin-3b is an antimicrobial peptide found in North America, Rana palustris (Pickerel frog, Lithobates palustris), and has activity against gram-negative bacteria Escherichia coli (MIC=1 μM). Alternative Names: Recombinant Rana palustris Palustrin-3b; L-Cysteine, glycyl-L-isoleucyl-L-phenylalanyl-L-prolyl-L-lysyl-L-isoleucyl-L-isoleucylglycyl-L-lysylglycyl-L-isoleucyl-L-lysyl-L-threonylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-isoleucyl-L-lysyl-L-seryl-L-leucyl-L-valyl-L-lysylglycyl-L-valylglycyl-L-methionyl-L-lysyl-L-valyl-L-phenylalanyl-L-lysyl-L-alanylglycyl-L-leucyl-L-seryl-L-asparaginyl-L-isoleucylglycyl-L-asparaginyl-L-threonylglycyl-L-cysteinyl-L-asparaginyl-L-α-glutamyl-L-α-aspartyl-L-α-glutamyl-, cyclic(43→48)-disulfide. Grades: >85%. CAS No. 326603-07-0. Molecular formula: C217H365N59O63S3. Mole weight: 4904.84.
Palustrin-Ca
Palustrin-Ca is an antimicrobial peptide found in Lithobates catesbeiana (American bullfrog, Rana catesbeiana), and has antimicrobial activity. Alternative Names: Gly-Phe-Leu-Asp-Ile-Ile-Lys-Asp-Thr-Gly-Lys-Glu-Phe-Ala-Val-Lys-Ile-Leu-Asn-Asn-Leu-Lys-Cys-Lys-Leu-Ala-Gly-Gly-Cys-Pro-Pro (Disulfide bridge: Cys23-Cys29). Grades: ≥95%. Molecular formula: C150H246N38O41S2. Mole weight: 3301.96.
Palustrin-GN1 antimicrobial peptide precursor
Palustrin-GN1 antimicrobial peptide precursor is an antimicrobial peptide found in Amolops granulosus (Granular torrent frog), and has antimicrobial activity. Alternative Names: Thr-Leu-Lys-Lys-Ser-Met-Leu-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys-Glu-Gln-Glu-Arg-Asn-Ala-Asp-Glu-Asp-Asp-Gly-Glu-Met-Thr-Glu-Glu. Grades: ≥97%. Molecular formula: C176H285N43O63S3. Mole weight: 4107.63.
Palustrin-OG1 antimicrobial peptide
Palustrin-OG1 antimicrobial peptide is an antimicrobial peptide found in Odorrana grahami (Yunnanfu frog), and has antimicrobial activity. Alternative Names: Palustrin-OG1; Gly-Leu-Trp-Asp-Thr-Ile-Lys-Gln-Ala-Gly-Lys-Lys-Phe-Phe-Leu-Asn-Val-Leu-Asp-Lys-Ile-Arg-Cys-Lys-Val-Ala-Gly-Gly-Cys-Arg-Thr (Disulfide bridge: Cys23-Cys29). Grades: ≥98%. Molecular formula: C156H255N45O40S2. Mole weight: 3465.15.
Palustrin-RA2 antimicrobial peptide
Palustrin-RA2 antimicrobial peptide is an antimicrobial peptide found in Rana andersonii (golden crossband frog), and has antimicrobial activity. Alternative Names: Ile-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys-Glu-Gln-Glu-Arg-Asp-Ala-Asp-Glu-Asp-Glu-Gly-Glu-Thr-Leu-Glu-Glu. Grades: ≥96%. Molecular formula: C112H181N29O51S. Mole weight: 2781.89.
Palustrin-RA peptide precursor
Palustrin-RA peptide precursor is an antimicrobial peptide found in Odorrana andersonii (golden crossband frog), and has antimicrobial activity. Alternative Names: Pro-Met-Lys-Lys-Ser-Leu-Leu-Leu-Leu-Phe-Phe-Ile-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys. Grades: ≥96%.
Palverafusp alfa
Palverafusp alfa (IMM-2510; SYN-2510) is a PD-L1/VEGF-targeting IgG1κ type humanized antibody. Palverafusp alfa blocks PD-1/PD-L1 binding, relieves immune suppression, mediates PD-L1-directed antibody-dependent cellular cytotoxicity (ADCC). Palverafusp alfa blocks VEGF/VEGFR binding, inhibits angiogenic signaling, relieves VEGF-induced immune suppression. Palverafusp alfa reduces endothelial cell proliferation, enhances ADCC and antibody-dependent cellular phagocytosis (ADCP), inhibits tumor growth, reverses T cell immune suppression. Palverafusp alfa exhibits immune stimulatory, antiangiogenic, and anti-tumor activity in the tumor microenvironment. Palverafusp alfa can be used for the research of cancer, such as solid tumors, non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMM-2510; SYN-2510. CAS No. 2850355-87-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990961.
PALYTOXIN
PALYTOXIN. Alternative Names: PTX; PALYTOXIN; (C52-55-HEMIACETAL) PALYTOXIN; PALYTOXIN (PTX) >97% (C52-55-HEMIACETAL) PA. Grades: 95%. CAS No. 77734-92-0. Molecular formula: C129H223N3O54.
PAM1
PAM1 is an antimicrobial peptide found in Ornithorhynchus anatinus, and has antibacterial and antifungal activity. Alternative Names: Arg-Thr-Lys-Arg-Arg-Ile-Lys-Leu-Ile-Lys-Asn-Gly-Val-Lys-Lys-Val-Lys-Asp-Ile-Leu-Lys-Asn-Asn-Asn-Ile-Ile-Ile-Leu-Pro-Gly-Ser-Asn-Glu-Lys; Platypus antimicrobial 1. Grades: ≥97%. Molecular formula: C175H318N56O46. Mole weight: 3942.82.
PAM2
PAM2 is an antimicrobial peptide found in Ornithorhynchus anatinus, and has antibacterial and antifungal activity. Alternative Names: Platypus antimicrobial 2; Arg-Pro-Trp-Ala-Gly-Asn-Gly-Ser-Val-His-Arg-Tyr-Thr-Val-Leu-Ser-Pro-Arg-Leu-Lys-Thr-Gln. Grades: ≥98%. Molecular formula: C112H179N37O30. Mole weight: 2523.89.
Pam2CSK4
Pam2CSK4. Group: Biochemicals. Grades: Purified. CAS No. 868247-72-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pam2CSK4 (Biotin)
Pam2CSK4 (Biotin). Group: Biochemicals. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Pam2Cys
Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection[1][2][3][4]. Use
Pam3CSK4
Pam3CSK4 is a TLR 1/2 agonist and a cell-permeable, water-soluble synthetic tripalmitoylated lipopeptide that mimics the acylated amino terminus of bacterial LPs. Bacterial LPs are a family of pro-inflammatory cell wall components found in both Gram-positive and Gram-negative bacteria. Pam3CSK4 is a potent activator of the pro-inflammatory transcription factor NF-κB. It induces production of TNF-α, superoxide, NO, and IL-6, stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells, promotes differentiation of naive CD4+ T cells into Th17 cells, and enhances tyrosine protein phosphorylation and activation of ERK1/2 and MEK1/2. It is used in prevention of inflammation caused by certain bacterial infection. Alternative Names: Pam3-Cys-Ser-Lys-Lys-Lys-Lys; (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH; P3CSK4; Pam3Cys-SK4; TLR1/TLR2 Agonist I; Pam3Cys-Ser-(Lys)4; Synthetic Triacylated Lipopeptide; L-Lysine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-N-(1-oxohexadecyl)-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-; L-Lysine, N2-[N2-[N2-[N2-[N-[S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-N-(1-oxohexadecyl)-L-cysteinyl]-L-seryl]-L-lysyl]-L-lysyl]-L-lysyl]-; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-N-(1-oxohexadecyl)-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine; P 3C; Pam3Cys-SKKKK; Pam3CysSK4. Grades: ≥95%. CAS No. 112208-00-1. Molecular formula: C81H156N10
Pam3CSK4 TFA
Pam3CSK4 TFA is a TLR 1/2 agonist and a cell-permeable, water-soluble synthetic tripalmitoylated lipopeptide that mimics the acylated amino terminus of bacterial LPs. Bacterial LPs are a family of pro-inflammatory cell wall components found in both Gram-positive and Gram-negative bacteria. Pam3CSK4 is a potent activator of the pro-inflammatory transcription factor NF-κB. It induces production of TNF-α, superoxide, NO, and IL-6, stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells, promotes differentiation of naive CD4+ T cells into Th17 cells, and enhances tyrosine protein phosphorylation and activation of ERK1/2 and MEK1/2. It is used in prevention of inflammation caused by certain bacterial infection. Alternative Names: Synthetic Triacylated Lipopeptide; Pam3Cys-Ser-(Lys)4 TFA; Pam3-Cys-Ser-Lys-Lys-Lys-Lys TFA salt; (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH TFA salt; P3CSK4 TFA; Pam3Cys-SK4 TFA; L-Lysine, N2-[N2-[N2-[N2-[N-[S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-N-(1-oxohexadecyl)-L-cysteinyl]-L-seryl]-L-lysyl]-L-lysyl]-L-lysyl]-, tris(trifluoroacetate) (salt). Grades: ≥95%. CAS No. 112208-01-2. Molecular formula: C87H159F9N10O19S. Mole weight: 1852.30.
Pam3CSK4 TFA
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pam3Cys-Ser-(Lys)4 TFA. CAS No. 112208-01-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1180A.
Pam3-Cys-OH
Pam3-Cys-OH. Alternative Names: Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine; N-Palmitoyl-2,3-bis(palmitoyloxy)-2-propylcysteine; Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-OH. CAS No. 87420-41-5. Molecular formula: C54H103NO7S. Mole weight: 910.46.
Pamabrom
A diuretic used to reduce menstrual pains. Group: Biochemicals. Alternative Names: 8-Bromo-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione 2-Amino-2-methyl-1-propanol; 2-Amino-2-methyl-1-propanol 8-bromotheophyllinate; Predema; Premsyn PMS; Sunril; Diurex. Grades: Highly Purified. CAS No. 606-04-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
PAMAM-25% C12 dendrimer, generation 2 solution
We offer a diverse selection of dendrimers containing a large number of peripheral groups. CAS No. 204401-84-3. Mole weight: 4730.72.
PAMAM-25% C12 dendrimer, generation 3 solution
We offer a diverse selection of dendrimers containing a large number of peripheral groups. CAS No. 204401-84-3. Mole weight: 9857.93.
PAMAM-25% C12 dendrimer, generation 4 solution
We offer a diverse selection of dendrimers containing a large number of peripheral groups. CAS No. 204401-84-3. Mole weight: 20112.35.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Molecular formula: [NH2(CH2)4NH2]:(G=1);dendri PAMAM(NH2)8. Mole weight: 1457.90.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Molecular formula: [NH2(CH2)4NH2]:(G=6);dendri PAMAM(NH2)256. Mole weight: 58074.17.
This product is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent. Molecular formula: [NH2CH2CH2SSCH2CH2NH2]:(G=2);dendri PAMAM(NH2)16. Mole weight: 3348.36.
We offer a diverse selection of dendrimers containing a large number of peripheral groups. Alternative Names: PAMAM dendrimer, cystamine core, generation 5.0 solution. Molecular formula: [NH2CH2CH2SSCH2CH2NH2]:(G=5);dendri PAMAM(NH2)128. Mole weight: 28917.00.
This product is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent. Molecular formula: [NH2(CH2)2NH2]:(G=0.5);dendri PAMAM(NHCH2CH2COONa)8. Mole weight: 1269.04. SMILES: [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CCN(CCNC(=O)CCN(CCN(CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC([O-])=O. InChI: 1S/C46H80N10O20.8Na/c57-35(47-13-29-51(21-5-39(61)62)22-6-40(63)64)1-17-55(18-2-36(58)48-14-30-52(23-7-41(65)66)24-8-42(67)68)33-34-56(19-3-37(59)49-15-31-53(25-9-43(69)70)26-10-44(71)72)20-4-38(60)50-16-32-54(27-11-45(73)74)28-12-46(75)76;;;;;;;;/h1-34H2,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,71,72)(H,73,74)(H,75,76);;;;;;;;/q;8*+1/p-8.