A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin. Group: Biochemicals. Alternative Names: Elisor, Kopostat, Mevalotin, Pravachol, Pravaselect. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Pravastatin Sodium Impurity ?
Pravastatin Sodium Impurity ?. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151006-14-3. Molecular formula: C31H55NO7. Mole weight: 553.78. Catalog: APB151006143.
Pravastatin sodium salt
Pravastatin sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pravastatin sodium; Pravastatin Sodium. Appearance: White Crystalline Powder. CAS No. 81131-70-6. Molecular formula: C23H35O7Na. Mole weight: 446.51. Purity: 95%+. IUPACName: pravastatin sodium. Product ID: ACM81131706. Alfa Chemistry ISO 9001:2015 Certified.
Pravastatin Sodium Salt
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H35NaO7. CAS No. 81131-70-6. Prepack ID 32064288-1g. Molecular Weight 446.51. See USA prepack pricing.
Pravastatin Sodium Salt
Pravastatin sodium is the sodium salt of pravastatin, a ring- opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of micro-organisms, notablyAbsidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a b-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges. Pravastatin is used therapeutically to reduce LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. CAS No. 81131-70-6. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Pravastatin Sodium Salt
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C23H35NaO7. CAS No. 81131-70-6. Prepack ID 32064288-250mg. Molecular Weight 446.51. See USA prepack pricing.
Pravastatin (sodium) (Standard) is the analytical standard of Pravastatin (sodium). This product is intended for research and analytical applications. Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC 50 of 5.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: CS-514 (sodium) (Standard). CAS No. 81131-70-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0165AR.
Pravibismane
Pravibismane, also known as BisEDT, MBN 101, is an antibacterial agent against a broad range of gram-positive and gram-negative pathogens.liposomal bismuth-ethanedithiol-loaded tobramycin (LipoBiEDT-TOB reduced the production of quorum-sensing molecules and virulence factors and could highly improve the management of chronic pulmonary infection in cystic fibrosis patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pravibismane; BisEDT; MBN 101; MBN-101; MBN101; Bismuth ethanedithiol. Product Category: Others. Appearance: Solid powder. CAS No. 175880-68-9. Molecular formula: C6H12Bi2S6. Mole weight: 694.48. Purity: >98%. IUPACName: 2,2'-[ethane-1,2-diylbis(sulfanediyl)]bis(1,3,2-dithiabismolane). Canonical SMILES: [Bi]1(SCCS[Bi]2SCCS2)SCCS1. Product ID: ACM175880689. Alfa Chemistry ISO 9001:2015 Certified.
Praziquantel
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standardseuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: Praziquantel.
Praziquantel
Praziquantel - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Praziquantel
Anthelmintic, effective against flatworms. Group: Biochemicals. Alternative Names: 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; (+/-)-Praziquantel; Azinox; Biltricide; Cesol; Cysticide; Distocide; Droncit; Embay 8440; Prazinon; Pyquiton; Warmnil. Grades: Highly Purified. CAS No. 55268-74-1. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Praziquantel
Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55268-74-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B0244.
Praziquantel
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H24N2O2. CAS No. 55268-74-1. Prepack ID 27541701-5g. Molecular Weight 312.41. See USA prepack pricing.
Praziquantel
Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. Specifically, it is effective against schistosoma, Clonorchis sinensis the fish tapeworm Diphyllobothrium latum. Uses: Anthelmintics. Synonyms: 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; (+/-)-Praziquantel; Azinox; Biltricide; Cesol; Cysticide; Distocide; Droncit; Embay 8440; Prazinon; Pyquiton; Warmnil. Grade: >98%. CAS No. 55268-74-1. Molecular formula: C19H24N2O2. Mole weight: 312.41.
Praziquantel
analytical standard. Group: Application areas.
Praziquantel-(cyclohexyl-d11)
analytical standard. Group: Drugs & metabolites.
Praziquantel-d11
Labeled Praziquantel. Anthelmintic, effective against flatworms. Group: Biochemicals. Alternative Names: 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one; (+/-)-Praziquantel-d11; Azinox-d11; Biltricide-d11; Cesol-d11; Cysticide-d11; Distocide-d11; Droncit-d11; Embay 8440-d11; Prazinon-d11; Pyquiton-d11; Warmnil-d11. Grades: Highly Purified. CAS No. 1246343-36-1. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Praziquantel-[d11]
Praziquantel-[d11] is the labelled analogue of Praziquantel. Praziquantel can be used for the treatment of a number of types of parasitic worm infections. Specifically it is used for schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. Uses: The d11 isotope labelled praziquantel. Synonyms: Praziquantel-d11; 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-(pyrazino-d11)[2,1-a]isoquinolin-4-one. Grade: 95% by HPLC; 95% atom D. CAS No. 1246343-36-1. Molecular formula: C19H13D11N2O2. Mole weight: 323.47.
Praziquantel-D11
Praziquantel-D11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246343-36-1. Molecular formula: C19H13D11N2O2. Mole weight: 323.48. Catalog: APB1246343361.
Praziquantel EP Impurity B
Praziquantel EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125273-86-1. Molecular formula: C19H22N2O2. Mole weight: 310.4. Catalog: APB125273861.
Praziquantel EP Impurity C
Praziquantel EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125273-88-3. Molecular formula: C19H22N2O4. Mole weight: 342.4. Catalog: APB125273883.
Praziquantel Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Praziquantel Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Praziquantel Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Prazobind
Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC 50 =1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SZL 49. CAS No. 107021-36-3. Pack Sizes: 1 mg. Product ID: HY-118335.
Prazobind
Prazobind. Group: Biochemicals. Alternative Names: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-piperazine; SZL-49. Grades: Highly Purified. CAS No. 107021-36-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C23H27N5O3. US Biological Life Sciences.
a1-Adrenoceptor alkylating reagent. Group: Biochemicals. Alternative Names: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-piperazine; SZL-49. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Prazobind-d8
α1-Adrenoceptor alkylating reagent. A labeled Prazosin analog. Group: Biochemicals. Alternative Names: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-(piperazine-d8); SZL-49-d8. Grades: Highly Purified. CAS No. 1189701-23-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Prazobind-[d8]
Prazobind-[d8] is the labelled analogue of Prazobind. Prazobind is an α1-adrenergic receptor (AR) antagonist. Uses: Α1-adrenoceptor alkylating reagent. a labelled prazosin analog. Synonyms: Prazobind D8; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-(piperazine-d8). Grade: 95% by HPLC; 95% atom D. CAS No. 1189701-23-2. Molecular formula: C23H19D8N5O3. Mole weight: 429.54.
Prazosin
Prazosin is an α-adrenergic receptor antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimers disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 19216-56-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B0193.
Prazosin-d8
Labeled Prazosin. An antihypertensive. α1-Adrenergic blocker. Group: Biochemicals. Alternative Names: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8. Grades: Highly Purified. CAS No. 1006717-55-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Prazosin-d8
Prazosin-d 8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1006717-55-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193S.
Prazosin-[d8]
An isotope labelled Prazosin. Prazosin is an inverse agonist at alpha-1 adrenergic receptor. Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD). Synonyms: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8; Furazosin-d8; Lentopres-d8; NSC 292810-d8; Peripress-d8. Grade: >95%. CAS No. 1006717-55-0. Molecular formula: C19H13D8N5O4. Mole weight: 391.46.
Prazosin-d8 hydrochloride
Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189508-34-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193AS.
Prazosin hydrochloride
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders [1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC 50 of 0.15 nM [2].Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC 50 s of 1.8, and 13 μM, respectively [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19237-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0193A.
Prazosin hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Prazosin Hydrochloride
Prazosin Hydrochloride (Terazosin EP Impurity K) is an antihypertensive. α1-Adrenergic blocker. Prazosin hydrochloride, a quinazole derivative, is a very potent and highly selective antagonist for apha-1-adrenoceptors (affinity for alpha-1 is about 1000-fold greater than for alpha-2 receptors). Mainly used as a clinic vasodilator for blood pressure control without increasing the heart rate or significantly impairing sympathetic functions. Has also been used clinically to treat anxiety, PTSD, and panic disorder. An excellent candidate for research studying brain functions mediated through alpha-1-adrenergic receptors, such as reward, pleasure, aggression, fear, anxiety, and addiction. Group: Biochemicals. Alternative Names: [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone Hydrochloride; 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine Hydrochloride; Adversuten; Adverszuten; Alpress LP; Furazosin; Lentopres; NSC 292810; Peripress; Terazosin EP Impurity K. Grades: Highly Purified. CAS No. 19237-84-4. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 419.86r. US Biological Life Sciences.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
PR-bombesin
PR-bombesin is an antimicrobial peptide found in Bombina maxima (Chinese red belly toad), and has antimicrobial activity as some neuropeptides. Synonyms: Glu-Lys-Lys-Pro-Pro-Arg-Pro-Pro-Gln-Trp-Ala-Val-Gly-His-Phe-Met; proline rich bombesin-related peptide (PR-bombesin). Grade: ≥97%. Molecular formula: C89H133N25O20S. Mole weight: 1905.26.
pRc/CMV HBS Liposome
This liposome contains pRc/CMV HBS, which increases the level of secretory immunoglobulin IgA. It is only for research purposes. Group: Liposomal vaccine or adjuvant.
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
PrDPhAc
PrDPhAc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,6-Bis(9,9-diphenylacridin-10(9H)-yl)pyrazine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1982316-90-4. Molecular formula: C54H38N4. Mole weight: 742.91 g/mol. Product ID: ACM1982316904. Alfa Chemistry ISO 9001:2015 Certified.
PRDX1-IN-1
PRDX1-IN-1 is a selective inhibtor of PRDX1 with an IC50 value of 0.164 ?M. PRDX1-IN-1 can be used in researches related to cancer.PRDX1-IN-1 promots intracellular ROS accumulation, and inhibits the proliferation, invasion and migration of cancer cells besides inducing apoptosis. PRDX1-IN-1 could be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149394.
PRE-084 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 138847-85-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PRE-084 hydrochloride
PRE-084 hydrochloride is a highly selective σ1 receptor ( S1R ) agonist, with an IC 50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75136-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18100A.
for electrophoresis. Group: Fluorescence/luminescence spectroscopy.
Preclamol hydrochloride
Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-3-PPP hydrochloride. CAS No. 88768-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108698.
Preclamolum
Preclamolum. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-[(3R)-1-propylpiperidin-3-yl]phenol; Phenol, 3-(1-propyl-3-piperidinyl)-, (S)-; (-)-3-PPP; (-)-3-(3-Hydroxyphenyl)-N-n-propylpiperidine; (S)-(-)-3-PPP; (-)-3-(3-Hydroxyphenyl)-N-propylpiperidine. Product Category: Heterocyclic Organic Compound. CAS No. 85966-89-8. Molecular formula: C14H21NO. Mole weight: 219.322640 [g/mol]. Purity: 0.96. IUPACName: 3-(1-propylpiperidin-3-yl)phenol. Canonical SMILES: CCCN1CCCC(C1)C2=CC(=CC=C2)O. Product ID: ACM85966898. Alfa Chemistry ISO 9001:2015 Certified.
Preclinical Compound Library
A unique collection of 709 preclinical compounds for high throughput screening (HTS) and high content screening (HCS); - Hot lead compounds for new drug discovery and development; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3410. Categories: Preclinical Compounds Libraries.
Precocene I
99%. Group: Pesticides & metabolites standards.
Precocene II
Anti-juvenile hormones found in plants that induce reversible precocious metamorphosis and sterilization in insects by suppressing the function of the corpora allata gland. Group: Biochemicals. Alternative Names: 6,7-Dimethoxy-2,2-dimethyl-2H-1-benzopyran; 6, 7-Dimethoxy-2, 2-dimethylchromene; Ageratochromene. Grades: Highly Purified. CAS No. 644-06-4. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C13H16O3, Molecular Weight: 220.26. US Biological Life Sciences.
Worldwide
precorrin-2 C20-methyltransferase
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase. This enzyme participates in porphyrin and chlorophyll metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.130. CAS No. 131554-12-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1728; precorrin-2 C20-methyltransferase; EC 2.1.1.130; 131554-12-6. Cat No: EXWM-1728.
precorrin-2 dehydrogenase
This enzyme catalyses the second of three steps leading to the formation of siroheme from uroporphyrinogen III. The first step involves the donation of two S-adenosyl-L-methionine-derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to form precorrin-2 (EC 2.1.1.107, uroporphyrin-III C-methyltransferase) and the third step involves the chelation of ferrous iron to sirohydrochlorin to form siroheme (EC 4.99.1.4, sirohydrochlorin ferrochelatase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single multifunctional protein called CysG, whereas in Bacillus megaterium, three separate enzymes carry out each of the steps, with SirC being responsible for the above reaction. Group: Enzymes. Synonyms: Met8p; SirC; CysG. Enzyme Commission Number: EC 1.3.1.76. CAS No. 227184-47-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1345; precorrin-2 dehydrogenase; EC 1.3.1.76; 227184-47-6; Met8p; SirC; CysG. Cat No: EXWM-1345.
precorrin-3B C17-methyltransferase
In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. Group: Enzymes. Synonyms: precorrin-3 methyltransferase; CobJ. Enzyme Commission Number: EC 2.1.1.131. CAS No. 152787-64-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1729; precorrin-3B C17-methyltransferase; EC 2.1.1.131; 152787-64-9; precorrin-3 methyltransferase; CobJ. Cat No: EXWM-1729.
precorrin-3B synthase
An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. Group: Enzymes. Synonyms: precorrin-3X synthase; CobG. Enzyme Commission Number: EC 1.14.13.83. CAS No. 152787-63-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0891; precorrin-3B synthase; EC 1.14.13.83; 152787-63-8; precorrin-3X synthase; CobG. Cat No: EXWM-0891.
precorrin-4 C11-methyltransferase
In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. Group: Enzymes. Synonyms: precorrin-3 methylase; CobM. Enzyme Commission Number: EC 2.1.1.133. CAS No. 152787-65-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1731; precorrin-4 C11-methyltransferase; EC 2.1.1.133; 152787-65-0; precorrin-3 methylase; CobM. Cat No: EXWM-1731.
precorrin-6A reductase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is precorrin-6B:NADP+ oxidoreductase. Other names in common use include precorrin-6X reductase, and precorrin-6Y:NADP+ oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism. Group: Enzymes. Synonyms: precorrin-6X reductase; precorrin-6Y:NADP+ oxidoreductase. Enzyme Commission Number: EC 1.3.1.54. CAS No. 137573-72-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1325; precorrin-6A reductase; EC 1.3.1.54; 137573-72-9; precorrin-6X reductase; precorrin-6Y:NADP+ oxidoreductase. Cat No: EXWM-1325.
precorrin-6A synthase (deacetylating)
In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. Group: Enzymes. Synonyms: precorrin-6X synthase (deacetylating); CobF. Enzyme Commission Number: EC 2.1.1.152. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1748; precorrin-6A synthase (deacetylating); EC 2.1.1.152; precorrin-6X synthase (deacetylating); CobF. Cat No: EXWM-1748.
The enzyme, which participates in the aerobic adenosylcobalamin biosynthesis pathway, has S-adenosyl-L-methionine-dependent methyltransferase and decarboxylase activities. The enzyme is a fusion protein with two active sites; one catalyses the methylation at C15 and the decarboxylation, while the other catalyses the methylation at C5. Group: Enzymes. Synonyms: precorrin-6 methyltransferase; precorrin-6Y methylase; precorrin-6Y C5,15-methyltransferase (decarboxylating); cobL (gene name). Enzyme Commission Number: EC 2.1.1.132. CAS No. 162995-22-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1730; precorrin-6B C5,15-methyltransferase (decarboxylating); EC 2.1.1.132; 162995-22-4; precorrin-6 methyltransferase; precorrin-6Y methylase; precorrin-6Y C5,15-methyltransferase (decarboxylating); cobL (gene name). Cat No: EXWM-1730.
precorrin-8X methylmutase
The enzyme catalyses the the conversion of precorrin-8X to hydrogenobyrinate by methyl rearrangement, a step in the aerobic (late cobalt insertion) pathway of adenosylcobalamin biosynthesis. The equivalent enzyme in the anaerobic pathway is EC 5.4.99.60, precorrin-8 methylmutase. Group: Enzymes. Synonyms: precorrin isomerase; hydrogenobyrinic acid-binding protein; cobH (gene name). Enzyme Commission Number: EC 5.4.99.61. CAS No. 138238-71-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5604; precorrin-8X methylmutase; EC 5.4.99.61; 138238-71-8; precorrin isomerase; hydrogenobyrinic acid-binding protein; cobH (gene name). Cat No: EXWM-5604.