A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Primycin is a macrolide antibiotic produced by Str. primycini. It is active against gram-positive bacteria, mycobacteria and protozoa. Synonyms: Ebrimycin; Primycin A1. CAS No. 47917-41-9. Molecular formula: C55H103N3O17. Mole weight: 1078.4.
Prinomide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Prinomide, Prinomide [INN], UNII-6NHC09L02I, CGS 10787B, CID60352, LS-136994, C10958, 77639-66-8. Product Category: Heterocyclic Organic Compound. CAS No. 77639-66-8. Molecular formula: C15H13N3O2. Mole weight: 267.287. Purity: 0.96. IUPACName: 2-cyano-3-(1-methylpyrrol-2-yl)-3-oxo-N-phenylpropanamide. Canonical SMILES: CN1C=CC=C1C(=O)C(C#N)C(=O)NC2=CC=CC=C2. Density: 1.19g/cm³. Product ID: ACM77639668. Alfa Chemistry ISO 9001:2015 Certified.
Prinoxodan
Prinoxodan. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Prinoxodanum; RGW 2938; 3,4-Dihydro-3-methyl-6-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-2(1H)-quinazolinone; Prinoxodanum [INN-Latin]; Prinoxodano [INN-Spanish]; PRINOXODAN; 2(1H)-Quinazolinone,3,4-dihydro-3-methyl-6-(1,4,5,6-tetrahydro-6-oxo-3-pyridaziny. Product Category: Heterocyclic Organic Compound. CAS No. 111786-07-3. Molecular formula: C13H14N4O2. Mole weight: 258.275860 [g/mol]. Purity: 0.96. IUPACName: 3-methyl-6-(6-oxo-4,5-dihydro-1H-pyridazin-3-yl)-1,4-dihydroquinazolin-2-one. Canonical SMILES: CN1CC2=C(C=CC(=C2)C3=NNC(=O)CC3)NC1=O. Density: 1.47g/cm³. Product ID: ACM111786073. Alfa Chemistry ISO 9001:2015 Certified.
Prionidipene A
Prionidipene A, a promising chemical compound, exhibits therapeutic potential in treating neurological disorders including Alzheimer's disease. This inhibitor of the beta-site amyloid precursor protein cleaving enzyme curtails the production of amyloid beta peptides, an established hallmark of Alzheimer's disease. Interestingly, research proposes that Prionidipene A reduces amyloid beta levels in the brain, which in turn has therapeutic implications. Moreover, improved cognitive function was noted, suggesting that this compound could be a pivotal stepping stone in developing novel therapeutics for Alzheimer's disease. Grade: > 95%. CAS No. 2199455-72-4. Molecular formula: C21H26O3. Mole weight: 326.43.
Prion Protein (106-126) (human) (scrambled)
Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of human prion protein (106-126), which is an important control for studying the biological activity of prion protein peptides. According to circular dichroism analysis, the scrambled PrP 106-126 shows a random coil structure without aggregation, and is completely degraded after incubation with proteinase K and pronase for 30 minutes at 37°C. Synonyms: H-Asn-Gly-Ala-Lys-Ala-Leu-Met-Gly-Gly-His-Gly-Ala-Thr-Lys-Val-Met-Val-Gly-Ala-Ala-Ala-OH; L-asparagyl-glycyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-methionyl-glycyl-glycyl-L-histidyl-glycyl-L-alanyl-L-threonyl-L-lysyl-L-valyl-L-methionyl-L-valyl-glycyl-L-alanyl-L-alanyl-L-alanine; Prion Protein Fragment 106-126 Scrambled Human; PrP (106-126) (human) (scrambled). Grade: ≥90%. CAS No. 150469-23-1. Molecular formula: C80H138N26O24S2. Mole weight: 1912.24.
Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil [1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Norphytane. CAS No. 1921-70-6. Pack Sizes: 1 mL; 10 mM * 1 mL; 5 mL; 10 mL. Product ID: HY-N7819.
Pristane
Pristane is a natural product from shark liver oil and a non-antigenic adjuvant. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,6,10,14-Tetramethylpentadecane pristane. Product Category: Heterocyclic Organic Compound. Appearance: liquid. CAS No. 1921-70-6. Molecular formula: C19H40. Mole weight: 268.5. Purity: 95%+. IUPACName: 2,6,10,14-Tetramethylpentadecane. Canonical SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)C. Density: 0.783 g/mL at 20 °C (lit.). ECNumber: 217-650-8. Product ID: ACM1921706. Alfa Chemistry ISO 9001:2015 Certified.
Pristane
Pristane. CAS No: 1921-70-6
Sarchem Laboratories New Jersey NJ
Pristanic acid
Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1189-37-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113024.
Pristanic acid solution
mixture of isomers, ethanol solution, ?97% (GC). Group: Fluorescence/luminescence spectroscopy.
Pristimerin
Pristimerin is a potent and reversible monoacylglycerol lipase ( MGL ) inhibitor with an IC 50 of 93 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Celastrol methyl ester. CAS No. 1258-84-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1937.
25mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C73H89N11O17. CAS No. 270076-60-3. Prepack ID 31084931-25mg. Molecular Weight 1392.55. See USA prepack pricing.
Pristinamycin
Pristinamycin is a complex of antibiotics produced by streptomyces pristinaespiralis, containing two components Pristinamycin IA and Pristinamycin IIA. Pristinamycin IA is a macrolide, and Pristinamycin IIA (streptogramin A) is a depsipeptide. Pristinamycin has been indicated for the treatment of MRSA. Synonyms: Pyostacine; Stafac; Pristinamycine; Staphylomycin; Virginiamycin. CAS No. 270076-60-3. Molecular formula: C73H89N11O17. Mole weight: 1392.55.
Pristinamycin
Pristinamycin, produced by Streptomyces pristinaespiralis , is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycine. CAS No. 270076-60-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0279.
Pristinamycin IB
Pristinamycin IB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Ostreogrycin B2; Efepristin. CAS No. 57206-54-9. Molecular formula: C44H52N8O10. Mole weight: 852.93.
Pristinamycin IC
Pristinamycin IC is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Vernamycin B gamma. CAS No. 28979-74-0. Molecular formula: C44H52N8O10. Mole weight: 852.93.
Pristinamycin IIA
Pristinamycin IIA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: virginiamycin M1; Streptogramin A; Mikamycin A; Ostreogrycin a. Grade: ≥ 95%. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59.
Pristinamycin IIB
Pristinamycin IIB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Synonyms: Volpristin; Virginiamycin M2. CAS No. 21102-49-8. Molecular formula: C28H37N3O7. Mole weight: 527.61.
Pristine MWCNT
Pristine MWCNT. Group: Multi wall cnt. CAS No. 308068-56-6. >95% (MWCNT).
Pritelivir
Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex , exhibits antiviral activity in vitro and in animal models of herpes simplex virus ( HSV ) infection. Pritelivir is active against herpes simplex virus types 1 and 2 ( HSV-1 and HSV-2 ) with the IC 50 of 0.02 μM against HSV1-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC316; BAY 57-1293. CAS No. 348086-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15303.
Pritelivir mesylate
Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex , exhibits antiviral activity in vitro and in animal models of herpes simplex virus ( HSV ) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 ( HSV-1 and HSV-2 ) with the IC 50 of 0.02 μM against HSV1-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC316 mesylate; BAY 57-1293 mesylate. CAS No. 1428333-96-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15303A.
Pritelivir mesylate
Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhibitor. BAY 57-1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57-1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound shows profound antiviral activity in murine and rat lethal challenge models of disseminated herpes, in a murine zosteriform spread model of cutaneous disease, and in a murine ocular herpes model. It is active in parenteral, oral, and topical formulations. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pritelivir mesylate, BAY57-1293; BAY 57-1293; BAY-57-1293; BAY571293; BAY 571293; BAY-571293; AIC-316; AIC 316; AIC316. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1428333-96-3. Molecular formula: C19H22N4O6S3. Mole weight: 498.59. Purity: >98%. IUPACName: N-methyl-N-(4-methyl-5-sulfamoylthiazol-2-yl)-2-(4-(pyridin-2-yl)phenyl)acetamide mesylate. Canonical SMILES: O=C(N(C)C1=NC(C)=C(S(=O)(N)=O)S1)CC2=CC=C(C3=NC=CC=C3)C=C2.OS(=O)(C)=O. Product ID: ACM1428333963. Alfa Chemistry ISO 9001:2015 Certified.
Pritumumab
Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 499212-74-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99806.
Phosphatase of regenerating liver 3 (PRL-3, also known as PTP4A3) plays critical roles in cell proliferation, motility, and invasion, and thus contributes to cancer metastasis. PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits PRL-3 (IC50=900nM for human PRL-3 in vitro), with minimal activity against other phosphatases. It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. PRL-3 inhibitor has been used to elucidate the actions of this enzyme, demonstrating that it dephosphorylates Tyr783 on integrin beta1 and modulates VEGF-mediated endothelial cell migration. It dose-dependently inhibits the growth and triggers apoptosis in cancer cell lines. Group: Biochemicals. Alternative Names: 5-[[5-bromo-2-[(2-bromophenyl) methoxy] phenyl] methylene] -2- thioxo-4-thiazolidinone. Grades: Highly Purified. CAS No. 893449-38-2. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C17H11Br2NO2S2. US Biological Life Sciences.
PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated Ras pathway and can be used in the study of relapsed or refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1094210-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119264A.
PRMT5-IN-29 is a potent and orally active PRMT5 Inhibitor with an IC 50 of 1.5 μ&Mu. PRMT5-IN-29 has the potential for advanced cancers research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242788-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153422.
PRMT5-IN-35
PRMT5-IN-35 (Compound 87) is a potent, selective and orally active PRMT5 inhibitor with an IC 50 value of 1 nM. PRMT5-IN-35 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1989620-03-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160865.
PRMT6 active human
recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
PRMT6-IN-3 (compound 25) is a selective PRMT6 inhibitor with an IC 50 value of 192 nM. PRMT6-IN-3 can induce apoptosis in cancer cells and has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2890765-10-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152236.
PRMT Inhibitor VI (1- (Benzo[d][1, 2, 3]thiadiazol-6-yl) -3- (2-cyclohexenylethyl) urea, 1-(1,2,3-Benzothiadiazol-6-yl)-3-[2-(1-cyclohexen-1-yl)ethyl]urea, Protein Arginine Methyltransferase Inhibitor VI)
A benzothiadiazolyl-cyclohexenylethylurea compound that binds to protein arginine methyltransferase 3 at the dimer interface and selectively inhibits PRMT3 activity in an allosteric manner (IC50 = 1.6uM), while being non-competitive with respect to AdoMet (S-adenosyl-L-methionine; SAM) or peptide substrates (Ki = 2.9 and 4.2 mM, respectively). Exhibits little or no inhibitory activity against PRMT1/4/5/8 or protein lysine methyltransferases, EHMT1, SUV39H2, SETD7, and SETD8, even at concentrations above 100uM. Although cell-permeable, it is metabolically unstable and therefore not recommended for cell cultures or in vivo applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?OS, Primary Target: PRMT3. US Biological Life Sciences.
Worldwide
PRN1371
PRN1371 is a highly selective and potent FGFR1-4 and CSF1R inhibitor with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802929-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101768.
PRN694
PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1575818-46-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12680.
PRO-6E
PRO-6E is an oral active PROTAC based on Cereblon ligand, and induces the degradation of MET with maximum degradation of 81.9% at 1 μM in MKN-45 cells. PRO-6E inhibits tumor growth in vivo and in vitro. PRO-6E induces cell apoptosis and induces cell arrest (Sturcture Note:(Blue: Cereblon ligand (HY-103596), Black: linker?Pink: ALK/c-Met inhibitor Crizotinib (HY-50878)) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2353493-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160506.
Proadifen hydrochloride
Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC 50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A ( MAO-A ) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine ( DMT ) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-525A; U-5446; RP-5171. CAS No. 62-68-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1311.
Proadrenomedullin (45-92), human is an intermediate region fragment of proadrenomedullin (MR-proADM) containing 45-92 amino acids. Synonyms: Glu-Leu-Arg-Met-Ser-Ser-Ser-Tyr-Pro-Thr-Gly-Leu-Ala-Asp-Val-Lys-Ala-Gly-Pro-Ala-Gln-Thr-Leu-Ile-Arg-Pro-Gln-Asp-Met-Lys-Gly-Ala-Ser-Arg-Ser-Pro-Glu-Asp-Ser-Ser-Pro-Asp-Ala-Ala-Arg-Ile-Arg-Val. Grade: ≥95%. CAS No. 166798-69-2. Molecular formula: C215H359N67O73S2. Mole weight: 5114.76.
Pro-Ala-Trp-Phe-Arg
Pro-Ala-Trp-Phe-Arg. Synonyms: mut3-FITC.
Proanthocyanidins
Proanthocyanidin (Procyanidin) are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy. [1]. Uses: Scientific research. Group: Natural products. CAS No. 20347-71-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0794.
Proapoptotic Peptide, D-(KLAKLAK)2
Proapoptotic Peptide, D-(KLAKLAK)2 is a pro-apoptotic peptide that is effective against tumor growth and bacteria. Synonyms: H-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-NH2; D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysinamide. CAS No. 721397-24-6. Molecular formula: C72H139N21O14. Mole weight: 1523.11.
Pro-Asp TFA can down-regulate skin inflammation in mouse skin. Synonyms: H-Pro-Asp-OH.TFA; L-Prolyl-L-aspartic acid trifluoroacetic acid; PD TFA. Grade: ≥95%. CAS No. 2260917-56-2. Molecular formula: C9H14N2O5.C2HF3O2. Mole weight: 344.24.
Probable Antimicrobial peptide Con10
Probable Antimicrobial peptide Con10 is an antimicrobial peptide found in Opisthacanthus cayaporum (South American scorpion), and has antimicrobial activity. Synonyms: Phe-Trp-Ser-Phe-Leu-Val-Lys-Ala-Ala-Ser-Lys-Ile-Leu-Pro-Ser-Leu-Ile-Gly-Gly-Gly-Asp-Asp-Asn-Lys-Ser-Ser-Ser. Grade: ≥95%. Molecular formula: C129H202N32O39. Mole weight: 2825.22.
Probable antimicrobial peptide Con13
Probable antimicrobial peptide Con13 is an antimicrobial peptide found in Opisthacanthus cayaporum (South American scorpion), and has antibacterial and antifungal activity. Synonyms: Ser-Lys-Ile-Lys-Asp-Phe-Ala-Lys-Lys-Ala-Trp-Asn-Ser-Pro-Leu-Ala-Asn-Glu-Leu-Lys-Ser-Lys-Ala-Leu-Asn-Ala-Ala-Lys-Asn-Phe-Val-Ser-Glu-Lys-Ile-Gly-Ala-Thr-Pro. Grade: ≥97%. Molecular formula: C191H312N52O55. Mole weight: 4216.91.