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| Product | Description | |
|---|---|---|
| Prosta-8(12),13-dien-1-oicacid,15-hydroxy-9-oxo-,(13E,15S)- | Prosta-8(12),13-dien-1-oicacid,15-hydroxy-9-oxo-,(13E,15S)-. CAS No. 13345-51-2. Purity: >98%. Product ID: ACM13345512. Molecular formula: C20H32O4. Mole weight: 336.4657. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Prostacyclin sodium salt | Prostacyclin sodium salt. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-6,9-epoxy-11,15-dihydroxy-prosta-5,13-dien-1-oic acid sodium salt; Epoprostenol sodium; Flolan. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C20H32NaO5. US Biological Life Sciences. |  Worldwide |
| prostaglandin-A1 Δ-isomerase | Interconverts prostaglandin A1 and prostaglandin C1. Group: Enzymes. Synonyms: prostaglandin A isomerase. Enzyme Commission Number: EC 5.3.3.9. CAS No. 9055-01-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5506; prostaglandin-A1 Δ-isomerase; EC 5.3.3.9; 9055-01-0; prostaglandin A isomerase. Cat No: EXWM-5506. |  |
| Prostaglandin A2 | Prostaglandin A2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. Prostaglandin A2 is generally not present in mammals. Prostaglandin A2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. Prostaglandin A2 has also been shown to act as a vasodilator with natriuretic properties. Group: Biochemicals. Alternative Names: (5Z,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic Acid; 7-[2-(3-Hydroxy-1-octenyl)-5-oxo-3-cyclopenten-1-yl]-5-heptenoic Acid; (+)-Prostaglandin A2; (15S)-PGA2; 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostatrienoic Acid; 15(S)-Hydroxy-9-oxo-5-cis-10,13-trans-prostenoic Acid; 15(S)-Prostaglandin A2; 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienecarboxylic Acid; 15α-Hydroxy-9-oxo-cis-5,10,trans-13-prostatrienoic Acid; 5,6-cis-PGA2; Medullin; NSC 165561; PGA2. Grades: Highly Purified. CAS No. 13345-50-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin (Alprostadil) EP Impurity D | Prostaglandin (Alprostadil) EP Impurity D. Uses: For analytical and research use. CAS No. 20897-91-0. Molecular formula: C20H34O5. Mole weight: 354.49. Catalog: APB20897910. |  |
| Prostaglandin (Alprostadil) EP Impurity F | Prostaglandin (Alprostadil) EP Impurity F. Uses: For analytical and research use. CAS No. 21003-46-3. Molecular formula: C20H34O5. Mole weight: 354.49. Catalog: APB21003463. | |
| Prostaglandin d1 alcohol | Prostaglandin d1 alcohol. Alternative Names: Prostaglandin D1 Alcohol, CTK8G2617, 1176470-37-3. CAS No. 1176470-37-3. Purity: 96%. Product ID: ACM1176470373. Molecular formula: C20H36O4. Mole weight: 340.5. IUPAC Name: (2R,3R,4S)-4-hydroxy-3-(7-hydroxyheptyl)-2-[(3R)-3-hydroxyoct-1-enyl]cyclopentan-1-one. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Prostaglandin D2 | Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma. Prostaglandin D2 is the major postagrlandin produced by mast cells and is the primary prostaglandin in the brain. It causes vasodilation, induces inflammation, and its presence in hair follicles may be partially responsible for male pattern baldness. Prostaglandin D2 is released during asthmatic and allergic reactions. Group: Biochemicals. Alternative Names: (Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid; 11-Dehydroprostaglandin F2alpha, PGD2. Grades: Highly Purified. CAS No. 41598-07-6. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C20H32O5, Molecular Weight: 352.5. US Biological Life Sciences. | Worldwide |
| Prostaglandin D2 | Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGD2. CAS No. 41598-07-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101988. |  |
| Prostaglandin D2 Ethanolamide-d4 | Prostaglandin D2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: N-(2-Hydroxyethyl)-11-oxo-9α,15S-dihydroxyprosta-5Z,13E-dien-1-amide-d4. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences. | Worldwide |
| Prostaglandin derivative | Prostaglandin derivative. CAS No. 87007-31-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| prostaglandin-D synthase | Brings about the opening of the epidioxy bridge. Some enzymes require glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 Δ-isomerase; prostaglandin-R-prostaglandin D isomerase; PGH-PGD isomerase(5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate Δ-isomerase (incorrect); (5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase; prostaglandin endoperoxide Δ-isomerase; prostaglandin D synthetase. Enzyme Commission Number: EC 5.3.99.2. CAS No. 65802-85-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5510; prostaglandin-D synthase; EC 5.3.99.2; 65802-85-9; prostaglandin-H2 Δ-isomerase; prostaglandin-R-prostaglandin D isomerase; PGH-PGD isomerase(5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate Δ-isomerase (incorrect); (5,13)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase; prostaglandin endoperoxide Δ-isomerase; prostaglandin D synthetase. Cat No: EXWM-5510. | |
| Prostaglandin E1 | Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Alprostadil; PGE1. CAS No. 745-65-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0131. | |
| Prostaglandin E1 | 1mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H34O5. CAS No. 745-65-3. Prepack ID 13337083-1mg. Molecular Weight 354.48. See USA prepack pricing. |  |
| Prostaglandin E1 | A primary Prostaglandin; easily crystallized from purified biological extracts. Vasodilator (peripheral). Group: Biochemicals. Alternative Names: (11α,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic Acid; 3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-cyclopentaneheptanoic Acid; Alprostadil; Alprox TD; Caveject; Liprostin; ONO 1608; PGE1; Palux. Grades: Highly Purified. CAS No. 745-65-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin E2 | Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Category: Induced disease models products. Alternative Names: PGE2; Dinoprostone. CAS No. 363-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952. | |
| Prostaglandin E2-[3,3,4,4-d4] | Labelled Prostaglandin E2. Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Synonyms: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid-d4; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid-d4; (-)-Prostaglandin E2-d4; (15S)-Prostaglandin E2-d4; Cervidil-d4; Cerviprime-d4; Cerviprost-d4; Dinoprostone-d4; Minprostin E2-d4; PGE2-d4; Prepidil-d4; Primiprost-d4; Prostin E2-d4; l-PGE2-d4. CAS No. 34210-10-1. Molecular formula: C20H28D4O5. Mole weight: 356.50. |  |
| prostaglandin-E2 9-reductase | Reduces prostaglandin E2 to prostaglandin F2&alpha. A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds. May be identical with EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Enzyme Commission Number: EC 1.1.1.189. CAS No. 42613-35-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0091; prostaglandin-E2 9-reductase; EC 1.1.1.189; 42613-35-4; PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Cat No: EXWM-0091. | |
| Prostaglandin E2-d4 | Prostaglandin E2-d4 is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGE2-d4; Dinoprostone-d4. CAS No. 34210-10-1. Pack Sizes: 10 μg (1.40 mM * 20 μL in Methyl acetate); 50 μg (1.40 mM * 100 μL in Methyl acetate). Product ID: HY-101952S. | |
| Prostaglandin E2 (Dinoprostone) | The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. Inhibits NLRP3 by acting through receptor EP4 activation that increases cAMP and phosphorylates NLRP3 at serine 295 through PKA. PKA phosphorylation of NLRP3 inhibits the NLRP3 ATPase activity, which is required for assembly of NLRP3-ASC complexes. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid; (-)-Prostaglandin E2; (15S)-Prostaglandin E2; Cervidil; Cerviprime; Cerviprost; Dinoprostone; Minprostin E2; PGE2; Prepidil. Grades: Highly Purified. CAS No. 363-24-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Prostaglandin E2 Ethanolamide-d4 | Prostaglandin E2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; Prostamide E2; PGE2 ethanolamide. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences. | Worldwide |
| Prostaglandin E2 (GMP) | Prostaglandin E2 (GMP) is Prostaglandin E2 (HY-101952) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Prostaglandin E2, an inflammatory mediator, is a endogenous hormone-like substance that participate in a wide range of body functions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGE2 (GMP); Dinoprostone (GMP). CAS No. 363-24-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-101952G. | |
| Prostaglandin E2 (PGE2) | Prostaglandin E2 (PGE2, Dinoprostone) plays important effects in labour (softens cervix and causes uterine contraction) and also stimulates osteoblasts to release factors that stimulate bone resorption by osteoclasts. It is easy to discolor when stored in liquid environment for a long time. It is recommended to store it in powder form and try to use it as soon as possible! Group: Inhibitors. Alternative Names: Dinoprostone. CAS No. 363-24-6. Pack Sizes: 5mg. Product ID: S3003. Formula: C20H32O5. Smiles: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Prostaglandin E2 (Standard) | Prostaglandin E2 (Standard) is the analytical standard of Prostaglandin E2. This product is intended for research and analytical applications. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGE2(Standard); Dinoprostone (Standard). CAS No. 363-24-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952R. | |
| Prostaglandin E3 | Prostaglandin E3 is an eicosanoid derived from eicosapentaenoic acid. Prostaglandin E3 inhibits polarization towards M1 but promotes polarization of M2a macrophages. Prostaglandin E3 shows anti-inflammatory and anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 802-31-3. Pack Sizes: 50 μg (1.43 mM * 100 μL in Methyl acetate); 100 μg (1.43 mM * 200 μL in Methyl acetate). Product ID: HY-113481. | |
| prostaglandin-endoperoxide synthase | This enzyme acts both as a dioxygenase and as a peroxidase. Group: Enzymes. Synonyms: prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Enzyme Commission Number: EC 1.14.99.1. CAS No. 39391-18-9. COX-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1031; prostaglandin-endoperoxide synthase; EC 1.14.99.1; 39391-18-9; prostaglandin synthase; prostaglandin G/H synthase; (PG)H synthase; PG synthetase; prostaglandin synthetase; fatty acid cyclooxygenase; prostaglandin endoperoxide synthetase. Cat No: EXWM-1031. | |
| prostaglandin-E synthase | Brings about the opening of the epidioxy bridge. Requires glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Enzyme Commission Number: EC 5.3.99.3. CAS No. 52227-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5511; prostaglandin-E synthase; EC 5.3.99.3; 52227-79-9; prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Cat No: EXWM-5511. | |
| Prostaglandin F2a | Prostaglandin F2a. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic acid; (+)-Prostaglandin F2a. Grades: Highly Purified. CAS No. 551-11-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H34O5. US Biological Life Sciences. | Worldwide |
| Prostaglandin F2α-[d4] | Prostaglandin F2α-[d4] is a PGF2αR activator. Synonyms: Prostaglandin F2α D4. Grade: 95% atom D. CAS No. 34210-11-2. Molecular formula: C20H30D4O5. Mole weight: 358.51. | |
| Prostaglandin F2α Tromethamine Salt | One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both. Group: Biochemicals. Alternative Names: (5Z, 9α, 11α, 13E, 15S)-9, 11, 15-Trihydroxyprosta-5, 13-dien-1-oic Acid 2-Amino-2-(hydroxymethyl)-1,3-propanediol; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid Tromethamine; (+)-Prostaglandin F2α Tromethamine; 9α, 11α, 15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid Tromethamine; 9α,11α-PGF2 Tromethamine; 9α,11α-PGF2α Tromethamine; Prostaglandin F2α-tham; THAM PGF2α; Tromethamine Prostaglandin F2α; U 14583E; U 14585. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Prostaglandin F(2)(a) tris salt | Prostaglandin F(2)(a) tris salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 25mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| prostaglandin-F synthase | Reduces prostaglandin D2 and prostaglandin H2 to prostaglandin F2; prostaglandin D2 is not an intermediate in the reduction of prostaglandin H2. Also catalyses the reduction of a number of carbonyl compounds, such as 9,10-phenanthroquinone and 4-nitroacetophenone. Group: Enzymes. Synonyms: prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. PGF synthetase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0090; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9; prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase. Cat No: EXWM-0090. | |
| Prostaglandin F Synthase from human, Recombinant | PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways. Applications: Prostaglandin f synthase (pgf synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. prostaglandin f synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. pgf synthase is also used to study kidney and renal cell carcinoma. Group: Enzymes. Synonyms: prostaglandin-D2 11-reduc. Enzyme Commission Number: EC 1.1.1.188. CAS No. 55976-95-9. Purity: > 90% (SDS-PAGE). PGF synthetase. Mole weight: mol wt ~37 kDa. Storage: -70°C. Source: E. coli. Species: Human. prostaglandin-D2 11-reductase; reductase, 15-hydroxy-11-oxoprostaglandin; PGD2 11-ketoreductase; PGF2α synthetase; prostaglandin 11-ketoreductase; prostaglandin D2-ketoreductase; prostaglandin F synthase; prostaglandin F synthetase; synthetase, prostaglandin F2α; prostaglandin-D2 11-reductase; PGF synthetase; NADPH-dependent prostaglandin D2 11-keto reductase; prostaglandin 11-keto reductase; prostaglandin-F synthase; EC 1.1.1.188; 55976-95-9. Cat No: NATE-0552. | |
| Prostaglandin I2, Sodium Salt (PGI2, Prostacyclin) | Potent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Exhibits cytoprotective and fibrinolytic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| prostaglandin-I synthase | A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2 into prostaglandin I2 (prostacyclin). Group: Enzymes. Synonyms: prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Enzyme Commission Number: EC 5.3.99.4. CAS No. 65802-86-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5512; prostaglandin-I synthase; EC 5.3.99.4; 65802-86-0; prostacyclin synthase; prostacycline synthetase; prostagladin I2 synthetase; PGI2 synthase; PGI2 synthetase; (5Z,13E)-(15S)-9α,11α-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase. Cat No: EXWM-5512. | |
| Prostaglandin J2 | Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with Kis of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PGJ2. CAS No. 60203-57-8. Pack Sizes: 500 μg (14.95 mM * 100 μL in Methyl acetate). Product ID: HY-113366. | |
| prostamide/prostaglandin F2α synthase | The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2α. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. | |
| prostamide/prostaglandin F2α synthase | The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2&alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. Group: Enzymes. Synonyms: prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Enzyme Commission Number: EC 1.11.1.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0502; prostamide/prostaglandin F2α synthase; EC 1.11.1.20; prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Cat No: EXWM-0502. | |
| Prostate Specific Antigen-1 (153-161) | Prostate Specific Antigen-1 (153-161) is a bioactive peptide of Prostate Specific Antigen-1. Prostate-specific antigen is a protein made by cells in the prostate gland (both normal cells and cancer cells). PSA is mostly found in semen, but a small amount is also found in blood. Synonyms: PSA-1 (153-161). | |
| Prostate Specific Antigen (146-154) | Prostate Specific Antigen (146-154) is a truncated fragment of Prostate Specific Antigen. Prostate-specific antigen is a protein made by cells in the prostate gland (both normal cells and cancer cells). PSA is mostly found in semen, but a small amount is also found in blood. Synonyms: PSA (146-154); gamma-seminoprotein (146-154); kallikrein-3 (146-154); P-30 antigen (146-154). | |
| Prostate-specific antigen (165-174) | Prostate-specific antigen (165-174) is a peptide corresponding to residues 165-174 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (165-174); prostatic specific acid phosphatase (165-174). | |
| Prostate-specific antigen (178-187) | Prostate-specific antigen (178-187) is a peptide corresponding to residues 178-187 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (178-187); prostatic specific acid phosphatase (178-187). | |
| Prostate Specific Antigen Substrate | Prostate Specific Antigen Substrate is a highly specific fluorescent peptide substrate can be used for measuring prostate-specific antigen (PSA) enzymatic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380225-52-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5990. | |
| Prostatic acid phosphatase (112-120) | Prostatic acid phosphatase (112-120) is a peptide corresponding to residues 112-120 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (112-120); prostatic specific acid phosphatase (112-120). | |
| Prostatic acid phosphatase (18-26) | Prostatic acid phosphatase (18-26) is a peptide corresponding to residues 18-26 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (18-26); prostatic specific acid phosphatase (18-26). | |
| Prostatic acid phosphatase (299-307) | Prostatic acid phosphatase (299-307) is a peptide corresponding to residues 299-307 of Prostatic acid phosphatase. Prostatic acid phosphatase, an enzyme produced by the prostate, may be found in increased amounts in men who have prostate cancer or other diseases. Synonyms: PAP (299-307); prostatic specific acid phosphatase (299-307). | |
| Prostatic acid phosphatase from Human, recombinant | ACPP, also known as prostatic acid phosphatase isoform PAP, is a type I integral membrane protein of the plasma membrane and lysosomes, and a secreted form also exists. The concentration of ACPP is elevated in the circulation of prostate cancer patients, making the enzyme a marker for the progression of prostate cancer. Recombinant human ACPP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. Group: Enzymes. Synonyms: Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Enzyme Commission Number: EC 3.1.3.2. CAS No. 9001-77-8. Purity: > 95% by SDS-PAGE. Apase. Mole weight: 41.8 kDa. Activity: >100,000 units/mg. Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -70°C. Avoid repeated freezing and thawing cycles. Form: Liquid. Source: Baculovirus. Species: Human. Prostatic acid phosphatase; PAP; prostatic specific acid phosphatase; PSAP; EC 3.1.3.2; ACP; Acid Phos; 5'-nucleotidase; 5'-NT; Ecto-5'-nucleotidase; Thiamine monophosphatase; TMPase; PAPf39; ACPP; ACP-3, ACP3. Cat No: NATE-1673. | |
| Prostratin | Prostratin. Group: Biochemicals. Alternative Names: (1aR, 1bS, 4aR, 7aS, 7bR, 8R, 9aS)-9a-(Acetyloxy)-1, 1a, 1b, 4, 4a, 7a, 7b, 8, 9, 9a-decahydro-4a, 7b-dihydroxy-3-(hydroxymethyl)-1, 1, 6, 8-tetramethyl-5H-cyclopropa[3, 4]benz[1, 2-e]azulen-5-one. Grades: Highly Purified. CAS No. 60857-08-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H30O6. US Biological Life Sciences. | Worldwide |
| Prostratin | Prostratin, a natural terpenoid compound, is a PKC activator, with a Ki of 12.5 nM and shows inhibitory effect on HIV-1. Uses: Scientific research. Category: Signaling pathways. CAS No. 60857-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107421. | |
| PROTAC α-synuclein degrader 5 | PROTAC α-synuclein degrader 5 is a highly selective small-molecule degrader (PROTAC) of α-synuclein aggregates, with a DC50 of 7.51 μM and the highest degradation rate Dmax of 89%. PROTAC α-synuclein degrader 5 contains probe molecule sery308 and E3 ligase ligands. PROTAC α-synuclein degrader 5 can be used for neurological disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2781922-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-155021. | |
| PROTAC α-Synuclein/Tau degrader 1 | PROTAC α-Synuclein/Tau degrader 1 is a blood-brain barrier-penetrant dual PROTAC degrader of α-synuclein (α-Syn) and tau, with DC50 of 1.57 μM and 4.09 μM, respectively. PROTAC α-Synuclein/Tau degrader 1 binds to α-Syn and tau PFF, with KDs of 0.47 and 2.78 μM, respectively. PROTAC α-Synuclein/Tau degrader 1 exhibits degradation effect mediated by the ubiquitin-proteasome system (UPS). PROTAC α-Synuclein/Tau degrader 6 can be used for the study of Parkinsons disease (PD) (Pink: α-Synuclein/Tau ligand (HY-151035); Blue: CRBN ligase ligand (HY-14658); Black: Linker (HY-128803))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032208-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157839. | |
| PROTAC AR/AR-V7 degrader-1 | PROTAC AR/AR-V7 degrader-1 (27c) is a PROTAC-based and dual AR, AR-V7 degrader, with DC50 values of 2.67 and 2.64 μM for AR and AR-V7, respectively. PROTAC AR/AR-V7 degrader-1 (27c) induces apoptosis (Red: AR antagonist; Blue: E3 ligase ligand; Black: linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2841308-96-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162412. | |
| PROTAC AR Degrader-8 | PROTAC AR Degrader-8 is the PROTAC degrader for androgen receptor (AR) that degrades AR-FL with DC50s of 0.018 μM and 0.14 μM in 22Rv1 cell and LNCaP cell, degrades AR-V7 with DC50 of 0.026 μM in 22Rv1 cell. PROTAC AR Degrader-8 inhibits the proliferation of cancer cell 22Rv1 and LNCaP with IC50 values of 0.038 μM and 1.11 μM. PROTAC AR Degrader-8 arrests cell cycle at G2/M phase, induces apoptosis in 22Rv1 cell. PROTAC AR Degrader-8 exhibits anticancer efficacy in mouse and zebrafish model. PROTAC AR Degrader-8 can be used for the research of prostate cancer, castration-resistant prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3044108-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170329. | |
| PROTAC AR-V7 degrader-1 | PROTAC AR-V7 degrader-1 is an orally active and selective AR-V7 PROTAC degrader with a DC50 of 0.32 μM (in 22Rv1 cells). PROTAC AR-V7 degrader-1 can inhibit the proliferation of tumor cells and exhibit anti-tumor activity. PROTAC AR-V7 degrader-1 can be used for the research of cancers such as prostate cancer[1].(Pink: VPC-14228 (HY-117669); Black: linker (HY-W041652); Blue: VHL Ligand (HY-112078)). Uses: Scientific research. Category: Signaling pathways. CAS No. 2767440-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145479. | |
| PROTAC ATR degrader-1 | PROTAC ATR degrader-1 (compound ZS-7) is a potent PROTAC degrader of ataxia telangiectasia and Rad3-related (ATR), with DC50 of 0.53 μM. PROTAC ATR degrader-1 plays an importnt role in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2925916-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-157764. | |
| PROTAC ATR degrader-2 | PROTAC ATR degrader-2 is a selective ATR PROTAC degrader. PROTAC ATR degrader-2 degrades ATR in acute myeloid leukemia (AML) cells MV-4-11 and MOLM-13, with DC50 values of 22.9 nM and 34.5 nM, respectively. PROTAC ATR degrader-2 has an IC50 of 29.6 nM against ATR, and its IC50 values against ATM and PI3K are both greater than 2000 nM. PROTAC ATR degrader-2 induces apoptosis, DNA damage, and upregulates p53 expression. PROTAC ATR degrader-2 inhibits cancer cell proliferation through the kinase-independent function of ATR protein. PROTAC ATR degrader-2 is applicable to research related to acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3010273-12-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161615. | |
| PROTAC AURKA degrader 2 | PROTAC AURKA degrader 2 (compound D) is a potent and selective PROTAC AURKA degrader with an IC50 of 3.58 nM. PROTAC AURKA degrader 2 exhibits 21.6-fold selectivity for AURKA over AURKB (IC50 = 77.2 nM). PROTAC AURKA degrader 2 specifically depletes AURKA on the mitotic spindle[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3093582-13-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-180132. | |
| PROTAC Bcl2 degrader-1 | PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1[1] (Blue: CRBN ligand, Black: linker?Pink: Mcl-1/Bcl-2 inhibitor, Nap-1). Uses: Scientific research. Category: Signaling pathways. CAS No. 2378801-85-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125876. | |
| PROTAC BCL6 Degrader-3 | PROTAC BCL6 Degrader-3 (compound 92) is a BCL6 PROTAC degrader. PROTAC BCL6 Degrader-3 can be used for the study of cancer or an autoimmune disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3005272-58-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-186067. | |
| PROTAC BCR-ABL Degrader-1 | PROTAC BCR-ABL Degrader-1 (compound PROTAC 1) is a PROTAC with a 2-oxoethyl linker. PROTAC BCR-ABL Degrader-1 induces Bcr-Abl degradation in a ubiquitinproteasom-dependent manner. PROTAC BCR-ABL Degrader-1 exhibits antiproliferative activity against K562 cells, and has the potential to study cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3079412-59-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153415. | |
| PROTAC BET-binding moiety 1 | PROTAC BET-binding moiety 1 is a key intermediate for the synthesis of high-affinity BET inhibitors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093387-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-107451. | |
| PROTAC BET Degrader-1 | PROTAC BET Degrader-1 is a PROTAC connected by ligands for Cereblon and BET, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093386-22-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103633. | |
| PROTAC B-Raf degrader 1 | PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2364367-27-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111758. | |
| PROTAC BRAF-V600E degrader-1 | PROTAC BRAF-V600E degrader-1 (compound 23) is a potent PROTAC BRAF-V600E degrader whlie no degradation activity against BRAF-WT. PROTAC BRAF-V600E degrader-1 exhibits Kd values of 2.4 nM and 2 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-1 degrades BRAF-V600E via the ubiquitin-proteasome system (UPS) and inhibits the growth of melanoma cells[1]. (In the molecular structure, target protein ligand: BI-882370 (HY-107779), red part; E3 ubiquitin enzyme ligand: Pomalidomide (HY-10984), blue part; PROTAC linker: G007-LK (HY-12438), black part. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417296-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-137487. | |
| PROTAC BRD4 Degrader-10 | PROTAC BRD4 Degrader-10, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 1.3 and 18 nM, respectively. Synonyms: S-(3-(((((3R,5S)-1-((S)-15-(tert-butyl)-1-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulen-9-yl)-1,13-dioxo-5,8,11-trioxa-2,14-diazahexadecan-16-oyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)butan-2-yl) methanesulfonothioate. Grade: 98%. CAS No. 2417370-49-9. Molecular formula: C59H71F2N9O15S4. Mole weight: 1312.50. | |
| PROTAC BRD4 Degrader-11 | PROTAC BRD4 Degrader-11 is a PROTAC linked by ligands for von Hippel-Lindau and BRD4. It is conjugated with STEAP1 and CLL1 antibodies to degrade BRD4 protein in PC3 prostate cancer cells with DC50s of 0.23 nM and 0.38 nM, respectively. Synonyms: S-((R)-1-(((((3R,5S)-1-((S)-2-(11-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamido)undecanamido)-3,3-dimethylbutanoyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)propan-2-yl) methanesulfonothioate. Grade: 98%. Molecular formula: C61H75F2N9O12S4. Mole weight: 1292.56. | |
| PROTAC BRD4 Degrader-12 | PROTAC BRD4 Degrader-12, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.39 and 0.24 nM, respectively. Synonyms: S-(3-(((((3R,5S)-1-((S)-2-(11-(7-(3,5-difluoropyridin-2-yl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamido)undecanamido)-3,3-dimethylbutanoyl)-5-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-3-yl)oxy)carbonyl)oxy)butan-2-yl) methanesulfonothioate. Grade: 98%. CAS No. 2417370-90-0. Molecular formula: C62H77F2N9O12S4. Mole weight: 1306.58. | |
| PROTAC BRD4 Degrader-13 | PROTAC BRD4 Degrader-13, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with DC50s of 0.025 and 6.0 nM, respectively. CAS No. 2417370-71-7. Molecular formula: C68H85F2N11O17P2S2. Mole weight: 1492.54. | |
| PROTAC BRD4 Degrader-2 | PROTAC BRD4 Degrader-2 is a PROTAC connected by ligands for Cereblon and BRD4 with an IC50 of 14.2 nM against BRD4 BD1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2185795-53-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133136. | |
| PROTAC BRD4 Degrader-5-CO-PEG3-N3 | PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a PROTAC-linker Conjugate for PAC, comprises the BRD4 degrader (MZ 1 (HY-107425) analog) and PEG-based linker. PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTAC BRD4 Degrader-5-CO-PEG3-N3 can be used for the research of HER2-positive breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2704602-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133736. | |
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