A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Pseudomonas quinolone signal (PQS) is a quorum-sensing signaling molecule produced by Pseudomonas aeruginosa. The synthesis of Pseudomonas quinolone signal relies on the las quorum-sensing system, and its biological activity is associated with the rhl system. Pseudomonas quinolone signal regulates the expression of the virulence gene lasB. Additionally, Pseudomonas quinolone signal plays roles in iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, and host immune modulation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PQS. CAS No. 108985-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128200.
pseudomonic acid B
An impurity of Mupirocin, an antibiotic used for the treatment of certain skin infections. Alternative Names: (2E)-5,9-Anhydro-2,3,4-trideoxy-8-C-[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiranyl]methyl]-3-methyl-D-allo-non-2-enonic Acid 8-Carboxyoctyl Ester; [2E,8[2S,3S(1S,2S)]]-5,9-Anhydro-2,3,4-trideoxy-8-C-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-D-allo-non-2-enonic Acid 8-Carboxyoctyl Ester. Grades: > 95%. CAS No. 40980-51-6. Molecular formula: C26H44O10. Mole weight: 516.63.
Pseudomonic Acid C
Pseudomonic Acid C. Group: Biochemicals. Alternative Names: (2E)-5,9-Anhydro-2,3,4,8-tetradeoxy-8-(5-hydroxy-4-methyl-2-hexen-1-yl)-3-methyl-L-talo-Non-2-enonic Acid 8-Carboxyoctyl Ester; [2E,8(2E,4R,5S)]-5,9-Anhydro-2,3,4,8-tetradeoxy-8-(5-hydroxy-4-methyl-2-hexenyl)-3-methyl-L-talo-non-2-enonic Acid 8-Carboxyoctyl Ester; (+)-Pseudomonic acid C. Grades: Highly Purified. CAS No. 71980-98-8. Pack Sizes: 10mg. Molecular Formula: C26H44O8, Molecular Weight: 484.62. US Biological Life Sciences.
Worldwide
Pseudomonic acid D sodium
Pseudomonic acid D sodium. Group: Biochemicals. Alternative Names: [1 (E) , 2E, 8[2S, 3S (1S, 2S) ]]-5, 9-Anhydro-2, 3, 4, 8-tetradeoxy-8-[[3- (2-hydroxy-1-methylpropyl) oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic acid 8-carboxy-5-octenyl ester monosodium salt; Sodium pseudomonate D; Mupirocin Impurity C. Grades: Highly Purified. CAS No. 85178-60-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C26H41NaO9. US Biological Life Sciences.
Worldwide
Pseudomonic acid F
An impurity of Mupirocin, which is a carboxylic acid bacteriostatic / bactericidal antibiotic. Alternative Names: Mupirocin EP Impurity F; Mupirocin Calcium EP Impurity F; Pseudomonic acid N; Pseudomonic acid F; [2E,8[2S,3S(1S,2S)]]-5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-L-talo-non-2-enonic Acid 6-Carboxyhexyl Ester. Grades: > 95%. CAS No. 167842-64-0. Molecular formula: C24H40O9. Mole weight: 472.58.
pseudooxynicotine oxidase
Contains one non-covalently bound FAD molecule per dimer. This enzyme, characterized from the soil bacterium Pseudomonas sp. HZN6, is involved the nicotine degradation. Group: Enzymes. Enzyme Commission Number: EC 1.4.3.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1479; pseudooxynicotine oxidase; EC 1.4.3.24. Cat No: EXWM-1479.
Pseudopalmatine
Pseudopalmatine isolated from the herbs of Tinospora sinensis. Uses: Antiplasmodial activity; anti-ache ic50 values. Alternative Names: 5,6-Dihydro-2,3,10,11-tetramethoxydibenzo[a,g]quinolizinium;5,6-Dihydro-8-desmethylcoralyne; 2,3,10,11-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium. Grades: > 95%. CAS No. 19716-66-6. Molecular formula: C21H22NO4. Mole weight: 352.4.
Pseudopelletierine
Pseudopelletierine. Group: Biochemicals. Alternative Names: 9-Methyl-9-azabicyclo[3.3.1]nonan-3-one. Grades: Highly Purified. CAS No. 552-70-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C9H15NO. US Biological Life Sciences.
Worldwide
Pseudoprotodioscin
Pseudoprotodioscin. Group: Biochemicals. Grades: Plant Grade. CAS No. 102115-79-7. Pack Sizes: 10mg. Molecular Formula: C51H82O21, Molecular Weight: 1031.18. US Biological Life Sciences.
Worldwide
Pseudoprotogracillin
Pseudoprotogracillin. Group: Biochemicals. Grades: Plant Grade. CAS No. 637349-03-2. Pack Sizes: 20mg. Molecular Formula: C51H82O22, Molecular Weight: 1047.2. US Biological Life Sciences.
Worldwide
Pseudopyronines B
Pseudopyronines B is an alpha-pyrone antibiotic produced by Pseudomonas fluorescens. It exhibits activity against Staphylococcus aureus and Escherichia coli with IC50 of 2.5 and >64 μg/mL, respectively. Alternative Names: Sch 419560; Sch-419560. CAS No. 420782-01-0. Molecular formula: C18H30O3. Mole weight: 294.4.
Pseudo RACK1
Pseudo RACK1. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Pseudotaraxasterol isolated from the herbs of Taraxacum mongolicum Hand. Mazz. Alternative Names: (18α,19α)-Urs-20-en-3β-ol; Taraxaster-20-en-3β-ol;Taraxasterane-20-ene-3β-ol;(3beta,18alpha,19alpha)-Urs-20-en-3-ol. Grades: 0.95. CAS No. 464-98-2. Molecular formula: C30H50O. Mole weight: 426.7.
Pseudothymidine
Pseudothymidine is a C-nucleoside analog of thymidine. Grades: ≥ 97%. CAS No. 65358-15-8. Molecular formula: C10H14N2O5. Mole weight: 242.23.
Pseudothymidine
Pseudothymidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 65358-15-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H14N2O5. US Biological Life Sciences.
Worldwide
pseudotropine acyltransferase
This enzyme exhibits absolute specificity for the exo/3β configuration found in pseudotropine as tropine (tropan-3α-ol;see EC 2.3.1.185, tropine acyltransferase) and nortropine are not substrates. Acts on a wide range of aliphatic acyl-CoA derivatives, including acetyl-CoA, β-methylcrotonyl-CoA andtigloyl-CoA. Group: Enzymes. Synonyms: pseudotropine:acyl-CoA transferase; tigloyl-CoA:pseudotropine acyltransferase; acetyl-CoA:pseudotropine acyltransferase; pseudotropine acetyltransferase; pseudotropine tigloyltransferase; PAT. Enzyme Commission Number: EC 2.3.1.186. CAS No. 138440-78-5, 162535-26-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2128; pseudotropine acyltransferase; EC 2.3.1.186; 138440-78-5, 162535-26-4; pseudotropine:acyl-CoA transferase; tigloyl-CoA:pseudotropine acyltransferase; acetyl-CoA:pseudotropine acyltransferase; pseudotropine acetyltransferase; pseudotropine tigloyltransferase; PAT. Cat No: EXWM-2128.
Pseudouridimycin
Pseudouridimycin is a C-nucleoside analogue that selectively inhibits bacterial RNA polymerase. Pseudouridimycin is an antibiotic found in Streptomyces albus that has activity against Gram-positive and Gram-negative bacteria. Alternative Names: PUM; 2,4(1H,3H)-Pyrimidinedione, 5-(5-((N-(aminoiminomethyl)glycyl-N2-hydroxy-L-glutaminyl)amino)-5-deoxy-beta-D-ribofuranosyl)-; (1S)-1,4-Anhydro-5-[(N-carbamimidoylglycyl-N2-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-ribitol; D-Ribitol, 5-[[N-(aminoiminomethyl)glycyl-N2-hydroxy-L-glutaminyl]amino]-1,4-anhydro-5-deoxy-1-C-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)-, (1S)-. Grades: ≥95%. CAS No. 1566586-52-4. Molecular formula: C17H26N8O9. Mole weight: 486.44.
Pseudouridimycin
Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC50 of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PUM. CAS No. 1566586-52-4. Pack Sizes: 1 mg. Product ID: HY-125650.
Pseudouridine
An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called ? synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. Group: Biochemicals. Alternative Names: 5- β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-( β-D-Ribofuranosyl)uracil; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; Pseudouridine; ?-Uridine. Grades: Highly Purified. CAS No. 1445-07-4. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C9H12N2O6, Molecular Weight: 244.2. US Biological Life Sciences.
Worldwide
Pseudouridine
Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation.Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia.[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1445-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113061.
PseudoUridine 5'-monophosphate
A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Alternative Names: Pseudouridylic acid; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol; pseudouridine 5'-phosphate; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione; 5-b-D-Ribofuranosyluracil 5'-phosphate; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate. Grades: ≥95%. CAS No. 1157-60-4. Molecular formula: C9H13N2O9P. Mole weight: 324.18.
PseudoUridine 5'-monophosphate Sodium salt
A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Alternative Names: Pseudouridylic acid sodium salt; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol sodium salt; pseudouridine 5'-phosphate sodium salt; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione sodium salt; 5-b-D-Ribofuranosyluracil 5'-phosphate sodium salt; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate, sodium salt; pUMP Sodium Salt. Grades: >95%. Molecular formula: C9H13N2O9P.xNa. Mole weight: 324.18 (free acid).
pseudouridine 5'-phosphatase
Requires Mg2+ for activity. Group: Enzymes. Synonyms: pseudouridine 5'-monophosphatase; 5'-PsiMPase; HDHD1. Enzyme Commission Number: EC 3.1.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3703; pseudouridine 5'-phosphatase; EC 3.1.3.96; pseudouridine 5'-monophosphatase; 5'-PsiMPase; HDHD1. Cat No: EXWM-3703.
PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Alternative Names: Ψ; Pseudo-UTP; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione; 5-β-D-Ribofuranosyluracil 5'-Triphosphate; Pseudouridine Triphosphate; Pseudo UTP; pUTP. Grades: ≥95% by HPLC. CAS No. 1175-34-4. Molecular formula: C9H15N2O15P3. Mole weight: 484.14.
Pseudouridine 5'-triphosphate lithium salt
PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Alternative Names: Pseudo-UTP.4Li; pUTP tetralithium salt; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione tetralithium salt; Pseudo UTP tetralithium salt; 5-Ribosyl Uraci tetralithium salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate tetralithium Salt; Pseudouridine Triphosphate tetralithium Salt; Pseudo-UTP tetralithium salt. Grades: ≥98%. Molecular formula: C9H11Li4N2O15P3. Mole weight: 507.87.
PseudoUridine 5'-Triphosphate Sodium
PseudoUridine 5'-Triphosphate Sodium is a compound, finding extensive employment in the exploration of RNA modifications and nucleotide analogs. Alternative Names: pUTP Sodium; Sodium ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione Sodium salt; Pseudo UTP Sodium salt; 5-Ribosyl Uraci Sodium salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate Sodium Salt; Pseudouridine Triphosphate Sodium Salt; PseudoUridine 5'-Triphosphate; Pseudo UTP; Pseudo-UTP. Grades: ≥95%. Molecular formula: C9H15N2O15P3.xNa. Mole weight: 484.14 (free acid).
PseudoUridine 5'-Triphosphate Triethylamine Salt
PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Alternative Names: ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate Triethylamine Salt; 5-[5-O-[Hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-2,4(1H,3H)pyrimidinedione Triethylamine Salt; Pseudo UTP Triethylamine Salt; 5-Ribosyl Uraci Triethylamine Salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate Triethylamine Salt; Pseudouridine Triphosphate Triethylamine Salt. Grades: ≥95%. Molecular formula: C9H15N2O15P3.xC6H15N. Mole weight: 484.14 (free base).
Pseudouridine-5'-triphosphate trisodium salt
Pseudouridine-5'-triphosphate trisodium salt, an indispensable compound in the biomedical realm, serves as a synthetically modified nucleoside triphosphate integral to RNA studies. Exhibiting remarkable efficacy in combatting diverse human afflictions - anti-tumor, antiviral, and anticancer among many others - this compound has also been shown to mediate transcriptional regulation in bacterial populations and has been investigated in the context of metabolic syndromes like obesity. Alternative Names: Pseudo-UTP sodium salt; Pseudo-UTP trisodium salt; 5-Ribosyl Uracil trisodium salt; sodium ((2R,3S,4R,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 5'-triphospho-pseudouridine sodium salt; Pseudouridine 5'-triphosphate (trisodium). Grades: ≥97% by AX-HPLC. Molecular formula: C9H12N2Na3O15P3. Mole weight: 550.09.
Pseudouridine-5'-triphosphate trisodium salt, 100mM aqueous solution.Uridine analog as ribonucleate nucleotidyltransferase substrate. Group: Biochemicals. Alternative Names: Pseudo-UTP. Grades: Highly Purified. CAS No. 1175-34-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H12N2O15P3Na3, Molecular Weight: 550.09. US Biological Life Sciences.
Worldwide
PseudoUridine B
Pseudouridine B is an isomer of Pseudouridine from wheat bran. Alternative Names: α-pseudouridine; 5-α-D-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; Alpha-Pseudouridine; Uracil, 5-a-D-ribofuranosyl-. Grades: 99%. CAS No. 10017-66-0. Molecular formula: C9H12N2O6. Mole weight: 244.2.
Pseudouridine-Diphosphate
Pseudouridine-Diphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. Alternative Names: ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate. CAS No. 1168-39-4. Molecular formula: C9H14N2O12P2. Mole weight: 404.16.
pseudouridine kinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:pseudouridine 5'-phosphotransferase. This enzyme is also called pseudouridine kinase (phosphorylating). This enzyme participates in pyrimidine metabolism. Group: Enzymes. Synonyms: pseudouridine kinase (phosphorylating). Enzyme Commission Number: EC 2.7.1.83. CAS No. 62213-40-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3113; pseudouridine kinase; EC 2.7.1.83; 62213-40-5; pseudouridine kinase (phosphorylating). Cat No: EXWM-3113.
pseudouridylate synthase
The reaction it readily reversible. While the enzymes from Tetrahymena pyriformis and Agrobacterium tumefaciens produce pseudouridine 5'-phosphate the enzyme from Escherichia coli functions as a pseudouridine-5'-phosphate glycosidase in vivo. Group: Enzymes. Synonyms: pseudouridylic acid synthetase; pseudouridine monophosphate synthetase; 5-ribosyluracil 5-phosphate synthetase; pseudouridylate synthetase; upsilonUMP synthetase; uracil hydro-lyase (adding D-ribose 5-phosphate); YeiN; pseudouridine-5'-phosphate glycosidase. Enzyme Commission Number: EC 4.2.1.70. CAS No. 9023-35-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5056; pseudouridylate synthase; EC 4.2.1.70; 9023-35-2; pseudouridylic acid synthetase; pseudouridine monophosphate synthetase; 5-ribosyluracil 5-phosphate synthetase; pseudouridylate synthetase; upsilonUMP synthetase; uracil hydro-lyase (adding D-ribose 5-phosphate); YeiN; pseudouridine-5'-phosphate glycosidase. Cat No: EXWM-5056.
Pseudo Vardenafil
Vardenafil. Group: Biochemicals. Alternative Names: 2-[2-Ethoxy-5- (1-piperidinylsulfonyl) phenyl]-5-methyl-7-propylimidazo[5, 1-f][1, 2, 4]triazin-4 (1H) -one. Grades: Highly Purified. CAS No. 224788-34-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Pseurotin
Pseurotin A is a secondary metabolite of Aspergillus. It has effective neurogenesis activity in PC12 pheochromocytoma cells, induces multipolar and branched neurites equivalent to β-NGF (an endogenous neurotrophic factor), and also exhibits chitinase inhibition. And it has a synergistic effect with azole antifungal agents. Alternative Names: Pseurotin. Grades: >99% by HPLC. CAS No. 58523-30-1. Molecular formula: C22H25NO8. Mole weight: 431.43.
Pseurotin A
Pseurotin A is a fungal metabolite with an unusual hetero-spirocyclic ring system. It has been shown to have potent neuritogenic activity in PC12 phaechromocytoma cells, a useful model for adrenergic neuronal differentiation. Pseurotin A induced multipolar and branching neurites comparable to beta-NGF, an endogenous neurotrophic factor. Pseurotin A is also reported to exhibit chitinase inhibition and displays synergistic activity with azole antifungal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 58523-30-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pseurotin D
Isomeric to pseurotin A. Anticancer and antiparasitic compound. Apomorphine antagonist. Neuroleptic agent. Inhibitor of IgE production. Group: Biochemicals. Grades: Highly Purified. CAS No. 77409-68-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
As a metabolite of PSI-7977, PSI 352707 Ammonium Salt is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Alternative Names: (2S)-2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic Acid Ammonium Salt; O-Desisopropyl O-Desphenyl Sofosbuvir Ammonium Salt. Grades: 90%. Molecular formula: C13H19FN3O9P.xNH3. Mole weight: 411.28.
PSI-6206 13C
PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1256490-42-2. Product ID: API1256490422. Molecular formula: C10H13FN2O5. Mole weight: 264.23.
PSI-697
PSI-697 is an oral P-selectin inhibitor with an IC50 of 125 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: P-Selectin Inhibitor. CAS No. 851546-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15526.
PSI-7409
PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Category: Active pharmaceutical ingredients. CAS No. 1015073-42-3. Product ID: API1015073423. Molecular formula: C10H16FN2O14P3. Mole weight: 500.16.
PSI-7409 tetrasodium
PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1621884-22-7. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15745A.
PSI-7409 tetrasodium
PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively. Category: Active pharmaceutical ingredients. CAS No. 1621884-22-7. Product ID: API1621884227. Molecular formula: C10H16FN2Na4O14P3. Mole weight: 592.117.
PSI 7411
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Alternative Names: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI-7411; PSI7411; 2'-Fluoro-2'-methyl(up)-uridine-5'-monophosphate; 2'-F-2'-Me(up)-UMP; Sofosbuvir Impurity 34 (GS-606965). Grades: ≥95%. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.20.
PSI 7411 Ammonium Salt
PSI 7411 is used in biological studies as nucleotide analog polymerase inhibitor for hepatitis C virus QS-9851. Alternative Names: 2'-F-2'-Me(up)-UMP.NH4; 2'-Fluoro-2'-methyl(up)-uridine-5'-monophosphate, ammonium salt; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Ammonium Salt; Sofosbuvir Impurity 34 ammonium salt. Grades: ≥95% by HPLC. Molecular formula: C10H14FN2O8P.xNH3. Mole weight: 340.20 (free acid).
PSI-7976 is an inhibitor of HCV RNA replication with EC50 value of 1.07μM. PSI-7851 is a phosphoramidate prodrug of PSI-7411 and has potent anti-hepatitis C virus (HCV) activity. It is a mixture of two diastereoisomers. PSI-7976 is one of them. Another one is PSI-7977. PSI-7851 is firstly activated through being hydrolyzed by CatA and CES1in the liver cells. It is found that CatA prefers PSI-7977 as a substrate over PSI-7976 while CES1 preferentially hydrolyzes PSI-7976 over PSI-7977. Since CES1 does not express in clone A replicon cells, the ability of PSI-7976 and PSI-7977 to inhibit HCV RNA replication is different in these cells. PSI-7977 is more potent than PSI-7976 with EC50 value of 92nM. Alternative Names: Sofosbuvir (R)-Phosphate; (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. Grades: >98%. CAS No. 1190308-01-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.45.
Psicofuranine
Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. Antimetabolite of the purine biosynthesis. Group: Biochemicals. Alternative Names: 1'-C- (Hydroxymethyl) adenosine; 1'- (Hydroxymethyl) adenosine; 9- β-D-Psicofuranosyl-6-aminopurine; 9- β-D-Psicofuranosyladenine; Angustmycin C; NSC 53104; Psicofuranine; 9- β-D-psicofuranosyl-adenine; 9- β-D-Psicofuranosyl-9H-purin-6-amine. Grades: Highly Purified. CAS No. 1874-54-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
Worldwide
Psicose diacetonide
Psicose diacetonide is a chemical compound revered in the realms of the biomedical industry for its profound capabilities in studying a myriad of diseases, including the ominous cancer. Alternative Names: 2,3:4,5-Di-O-isopropylidene-a-D-psicopyranose. CAS No. 205582-81-6. Molecular formula: C12H20O6. Mole weight: 260.28.
Psidial A
Psidial A, a natural triterpenoid isolated from the leaves of Psidium guajava L, exhibits the activity to enzyme PTP1B and also reduces tumor growth and stimulates uterus proliferation. Uses: Anti-tumour. Alternative Names: (1S,4S,7R,11R,12R)-14,16-dihydroxy-1,5,5-trimethyl-8-methylidene-12-phenyl-19-oxatetracyclo[9.8.0.04,7.013,18]nonadeca-13,15,17-triene-15,17-dicarbaldehyde; 7,9-dihydroxy-2,2,4a- trimethyl-13-methylene-10-phenyl-1,2,2a,3,4,4a,10, 10a,11,12,13,13a-dodecahydrocyclobuta[6,7] cyclonona[b]chromene-6,8-dicarbaldehyde. Grades: >98%. CAS No. 1207181-35-8. Molecular formula: C30H34O5. Mole weight: 474.6.
PSiF-DBT
PSiF-DBT is a conductive polymer that can be used as an active layer with thermal stability and high degree of π-electron delocalization. It has a high mobility of charge carrier around 1×10-3cm2 /(V s) which can be useful in organic electronics. Alternative Names: Poly[2,7-(9,9-dioctyl-dibenzosilole)-alt-4,7-bis(thiophen-2-yl)benzo-2,1,3-thiadiazole], Poly[2,1,3-benzothiadiazole-4,7-diyl-2,5-thiophenediyl(9,9-dioctyl-9H-9-silafluorene-2,7-diyl)-2,5-thiophenediyl]. CAS No. 1004272-92-7. Molecular formula: (C42H46N2S3Si)n. Mole weight: average Mn 10000-80000.
Psi I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 50% of the dna fragments can be ligated and of these 95% can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. TTA↑TAA AAT↓ATT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Pseudomonas species-SE-G49. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1150RE.
PSI Reagent
PSI Reagent. CAS No. 2245335-71-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
PSMA-11
PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HBED-CC-PSMA. CAS No. 1366302-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125399.
PSMA (27-38)
Prostate-specific membrane antigen (PSMA) is considered an ideal target for antigen-redirected immunotherapy because it is expressed at the surface of prostate cancer cells, present in all tumor stages, and shows an increased expression in androgen-independent and metastatic stages of the disease. Alternative Names: Prostate-specific membrane antigen (27-38).
PSMA-ALB-56
PSMA-ALB-56 is a PSMA-targeting radioligand designed by combining the glutamate-urea PSMA-binding entity and an albumin binder[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2306049-48-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141536.
PSMA-azide
PSMA-azide is a prostate-specific membrane antigen (PSMA) ligand. PSMA-azide inhibits PSMA-dependent NAAG (N-acetylaspartylglutamic acid) hydrolysis, with an IC50 of 9 nM and a Ki of 1 nM. PSMA-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2374814-84-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-160893.
PSMA-BCH
PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NOTA-PSMA. CAS No. 1703768-73-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-155483.
PSMA binder-1
PSMA binder-1 is a ligand for PSMA and can be used to synthesize PSMA targeting molecule, such as Ac-PSMA-trillium[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170653-14-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158123.
PSMA I&S
PSMA I&S is a precursor of the 99mTc-labeled PSMA-targeting ligand[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2639475-07-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148152.
PSMα2
PSMα2 is a potent PSM (phenol-soluble modulin) peptide toward mouse neutrophils, led to strong influx of leukocytes[1]. Uses: Scientific research. Category: Peptides. CAS No. 1092844-32-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10629.
PSMα3
PSMα3 is an inhibitor of NF-κB p65 and p38 MAPK. PSMα3 forms membrane pores and binds to residues of human insulin B chain to inhibit insulin aggregation. PSMα3 forms α-type amyloid-like fibrils to exert cytotoxic effects, and acts as a functional amyloid virulence determinant of Staphylococcus aureus. PSMα3 is applicable to research related to spondyloarthritis, rheumatoid arthritis, insulin-derived amyloidosis, and Staphylococcus aureus infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1001405-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2358.
PSMA-PEG4
PSMA-PEG4. Alternative Names: (21S,25S)-1-Amino-15,23-dioxo-3,6,9,12-tetraoxa-16,22,24-triazaheptacosane-21,25,27-tricarboxylic acid. CAS No. 2256069-92-6. Molecular formula: C23H42N4O12. Mole weight: 566.60.
PSMA/PSM-P1 (4-12)
This peptide is a tetramer of biotinylated peptide with streptavidin mainly composed of PSMA-derived peptide of LLHETDSAV sequence covering 4-12 and A*0201 molecule.
PSMA-Val-Cit-PAB-MMAE
PSMA-Val-Cit-PAB-MMAE is a small-molecule conjugate targeting PSMA, with Monomethyl auristatin E (MMAE) (HY-15162) as its cytotoxic payload. PSMA-Val-Cit-PAB-MMAE binds to PSMA, thereby being delivered into PSMA-expressing prostate cancer cells. Subsequently, the Val-Cit linker is cleaved under the mediation of cathepsin B, releasing active MMAE. PSMA-Val-Cit-PAB-MMAE inhibits CYP3A4 activity (IC50 = 11.2 μM), induces intracellular ROS production and oxidative stress, disrupts the cytoskeleton through microtubule destabilization, and induces prostate cancer cell death. PSMA-Val-Cit-PAB-MMAE can be used in research related to prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748039-79-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141860.
PSM P2 (711-719)
PSM P2 (711-719) is a 9-aa peptide. PSM P2 is a zinc metalloenzyme that resides in membranes. It is mainly expressed in four tissues of the body, including prostate epithelium, the proximal tubules of the kidney, the jejunal brush border of the small intestine and ganglia of the nervous system. Alternative Names: Glutamate carboxypeptidase 2 (711-719); N-acetyl-L-aspartyl-L-glutamate peptidase I (711-719); NAAG peptidase (711-719); prostate-specific membrane antigen (PSMA) (711-719).
PSN 375963
PSN 375963 is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 388575-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108258.