A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a K i = 4-8 nM and an IC 50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 903580-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14559.
PRX-07034 hydrochloride
PRX-07034 is a potent and selective 5-HT6 receptor antagonist. It was shown to improve cognition and memory in rats. Synonyms: PRX-07034; PRX07034; PRX 07034; PRX-07034 HCl; N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloride. Grades: ≥98% by HPLC. CAS No. 903580-39-2. Molecular formula: C21H28ClN3O4S·HCl. Mole weight: 490.44.
PRX 08066
PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It can potentially inhibit the pathologic 5-HT-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (PAH). It reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. It shows effects on the vascular muscularization induced by 5-HT in the in vitro studies. It inhibits 5-HT-induced mitogen-activated protein kinase activation and markedly reduces thymidine incorporation in Chinese hamster ovary cells expressing the human 5-HT2BR in vitro. It decrea...ts and mice without affecting the systemic mean arterial pressure in the animals. It is also found to have anti-proliferative and anti-fibrotic effects. It was developed by Allergan company and is in clinical phase 2 with no progression. Uses: Prx 08066 can potentially inhibit the pathologic 5-ht-induced vascular muscularization and is developed to treat for pulmonary arterial hypertension (pah). it is also found to have anti-proliferative and anti-fibrotic effects. Synonyms: PRX-08066; PRX 08066; PRX08066. 5-[[4-[(6-chlorothieno[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]methyl]-2-fluorobenzonitrile. Grades: >98%. CAS No. 866206-54-4. Molecular formula: C19H17ClFN5S. Mole weight: 401.89.
PRX-08066
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3. Uses: Scientific research. Group: Signaling pathways. CAS No. 866206-54-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15472.
PRX-08066 maleic acid
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 value of 3.4 nM. Synonyms: PRX-08066 maleate; 5-[[4-[(6-Chlorothieno[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl]methyl]-2-fluoro-benzonitrile (2Z)-2-Butenedioate. CAS No. 866206-55-5. Molecular formula: C19H17ClFN5S·C4H4O4. Mole weight: 517.96.
Przewalskinic acid A. Group: Biochemicals. CAS No. 136112-75-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Przewalskinic acid A
Przewalskinic acid A is found in the Salvia przewalskii Maxim herb. Synonyms: Przewalskinic acid A; 136112-75-9; (2R,3R)-4-[(E)-2-carboxyethenyl]-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-3-carboxylic acid; 7-Epiblechnic acid; HY-N5057. Grades: >98%. CAS No. 136112-75-9. Molecular formula: C18H14O8. Mole weight: 358.3.
PS10
PS10 is a novel, potent and ATP-competitive pan- PDK inhibitor, inhibits all PDK isoforms with IC 50 of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively. PS10 shows high affinity for PDK2 ( K d = 239 nM) than for Hsp90 (K d = 47 μM) [1]. PS10 improves glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity. PS10 has the potential for the investigation of diabetic cardiomyopathy [2].PDK: pyruvate dehydrogenase kinase. Uses: Scientific research. Group: Signaling pathways. CAS No. 1564265-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121744.
PS-1145
PS-1145 is a selective IκB kinase (IKK) inhibitor (IC50 = 100 nM). PS1145 efficiently inhibited both basal and induced NF-kappaB activity in PC cells. Synonyms: N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide; PS-1145; PS 1145; PS1145. Grades: 98%. CAS No. 431898-65-6. Molecular formula: C17H11ClN4O. Mole weight: 322.75.
PS 1145 dihydrochloride
PS 1145 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1049743-58-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PS 1145 dihydrochloride
PS 1145 is a highly specific small-molecule IKK inhibitor (IC50 = 100 nM). Through this action, it is used to elucidate roles for NF-κB both in cells and in vivo. Effects of PS 1145 on proliferation and apoptosis correlated with inhibition of interleukin (IL)-6, cyclin D1, D2, inhibitor of apoptosis (IAP)-1 and IAP-2 gene expression and decreased IL-6 protein level. Synonyms: N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide; PS 1145 dihydrochloride; PS-1145 dihydrochloride; PS1145 dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1049743-58-9. Molecular formula: C17H11ClN4O.2HCl. Mole weight: 395.67.
PS210
PS210 is a potent and selective PDK1 activator with a K d of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221962-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121629.
PS423
PS423 is a prodrug of PS210, acting as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K. PS210 is a potent and selective PDK1 activator targeting the PIF binding pocket of PDK1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221964-37-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124060.
PS47
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13851.
PS 47
PS 47 is an inactive E-isomer of the PDK1 activator PS 48. In combination with PS 48, PS 47 can be used as a negative control. Synonyms: PS-47; PS 47; PS47; (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid. Grades: 99%. CAS No. 1180676-33-8. Molecular formula: C17H15ClO2. Mole weight: 286.75.
PS48
PS48 is an activator of PDK1 with an AC 50 of 8 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15967.
PS 48
PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1, PDK1) activator (Kd = 10.3 μM). Studies have indicated that this compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1). This is a distinct region separate from the ATP binding site. Applications: A phosphoinositide-dependent protein kinase-1 (pdk1) activator. Group: Coenzymes. Synonyms: (Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid. CAS No. 1180676-32-7. Mole weight: 286.76. Form: Solid. (Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid; PS 48; 1180676-32-7. Cat No: COEC-117.
PS 48
PS 48 is an allosteric activator of phosphoinositide-dependent protein kinase 1 (PDPK1; PDK1) binding to the PIF-binding pocket of PDK1. Synonyms: PS-48; PS 48; PS48; (Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid; (2z)-5-(4-Chlorophenyl)-3-Phenylpent-2-Enoic Acid. Grades: 99%. CAS No. 1180676-32-7. Molecular formula: C17H15ClO2. Mole weight: 286.75.
PS 48
PS 48. Group: Biochemicals. Grades: Purified. CAS No. 1180676-32-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PS-5
PS-5 is a beta-lactam antibiotic isolated from Streptomyces sp. A271. It is effective against gram-positive and gram-negative bacteria. Synonyms: PS 5; PS5; Antibiotic PS 5. CAS No. 67007-79-8. Molecular formula: C13H18N2O4S. Mole weight: 298.36.
PS-6
PS-6 is a beta-lactam antibiotic that can be isolated from Streptomyces cremeus subsp. auratilis, Str. fulvoviridis A-933, Str. olivaceus and Str. flavo-griseus NRRL 8139. It is effective against gram-positive and gram-negative bacteria. Synonyms: PS 6; PS6; Antibiotic PS 6. CAS No. 72615-19-1. Molecular formula: C14H20N2O4S. Mole weight: 312.39.
PS-7
PS-7 is a beta-lactam antibiotic that can be isolated from Streptomyces cremeus subsp. auratilis, Str. fulvoviridis A-933, Str. olivaceus and Str. flavo-griseus NRRL 8139. It is effective against gram-positive and gram-negative bacteria. Synonyms: PS 7; PS7; Antibiotic PS 7. CAS No. 72615-18-0. Molecular formula: C13H16N2O4S. Mole weight: 296.34.
PS-8
PS-8 is a beta-lactam antibiotic isolated from Streptomyces cremeus subsp. auratilis A 272. It is effective against gram-positive and gram-negative bacteria. Synonyms: PS 8; PS8; Antibiotic PS 8. Molecular formula: C14H18N2O4S. Mole weight: 310.37.
PS-990
PS-990 is a metabolite produced by Acremonium sp. KY12702. It induced neurite formation in a murine neuroblastoma cell line, Neuro2A. Synonyms: PS 990; PS990. CAS No. 158792-23-5. Molecular formula: C32H36O10. Mole weight: 580.6.
PSA1 141-150 acetate
PSA1 (141-150) is a prostate-specific antigen 1 peptide used for immunotherapy in cancer trials. Molecular formula: C57H97N13O15S. Mole weight: 1236.52.
Psacotheasin
Psacotheasin is a 34-mer knottin-type antimicrobial peptide found in Psacothea hilaris larvae. It has antifungal properties but has no hemolytic activity against human erythrocytes. It has antibacterial activity against both gram-positive and gram-negative bacterial strains. Grades: >98%. Molecular formula: C143H220N46O44S6. Mole weight: 3479.96.
p-Salicylic Acid
Acetylsalicylic Acid Impurity A. Group: Biochemicals. Grades: Highly Purified. CAS No. 99-96-7. Pack Sizes: 1g, 10g, 50g, 100g, 500g. Molecular Formula: C?H?O?. US Biological Life Sciences.
Worldwide
p-Salicylic Acid 4-Glucuronide Potassium Salt
p-Salicylic Acid 4-Glucuronide Potassium Salt. Group: Biochemicals. Alternative Names: 4-Carboxyphenyl β-D-Glucopyranosiduronic Acid Potassium Salt; p-Carboxyphenyl glucosiduronic Acid Potassium Salt. Grades: Highly Purified. CAS No. 1376574-47-8. Pack Sizes: 5mg. Molecular Formula: C13H12K2O9, Molecular Weight: 390.43. US Biological Life Sciences.
Psalmopeotoxin-1 is an antimicrobial peptide found in Psalmopoeus cambridgei (Trinidad chevron tarantula), and has antiparasitic activity against Plasmodium falciparum (IC50=1.59 μM). Synonyms: U1-theraphotoxin-Pc1a; U1-TRTX-Pc1a; PcFK1. Grades: >98%. Molecular formula: C153H247N47O43S6. Mole weight: 3625.29.
Psalmopeotoxin-2
Psalmopeotoxin-2 is an antimicrobial peptide found in Psalmopoeus cambridgei (Trinidad chevron tarantula), and has antiparasitic activity against Plasmodium falciparum (IC50=1.15 μM). Synonyms: U2-theraphotoxin-Pc1a; U2-TRTX-Pc1a; PcFK2. Grades: >98%. Molecular formula: C116H203N41O35S7. Mole weight: 2956.56.
Psalmotoxin 1
Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). Psalmotoxin 1 is a potent and slective ASIC1a inhibitor (IC 50 : 0.9 nM) by increasing the apparent affinity for H + of ASIC1a. Psalmotoxin 1 can induce cell apoptosis , also inhibits cell migration, proferliration and invasion of cancer cells. Psalmotoxin 1 can be used in the research of cancers, or neurological disease [1] [3] [4] [6]. Uses: Scientific research. Group: Peptides. Alternative Names: PcTx1; Psalmopoeus cambridgei toxin-1. CAS No. 880107-52-8. Pack Sizes: 100 μg. Product ID: HY-P1411.
Psalmotoxin 1
Psalmotoxin 1 (PcTx1) is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker (IC50 = 0.9 nM) and not other members of the family. The blockade is rapidly reversible. PcTx1 has been successfully expressed to produce a spider toxin of the drosophila melanogaster S2 cell for the first time. It displays potent analgesic properties against thermal, mechanical, chemical, inflammatory and neuropathic pain in rodents. Synonyms: PcTx1; Psalmopoeus cambridgei toxin-1; Glu-Asp-Cys-Ile-Pro-Lys-Trp-Lys-Gly-Cys-Val-Asn-Arg-His-Gly-Asp-Cys-Cys-Glu-Gly-Leu-Glu-Cys-Trp-Lys-Arg-Arg-Arg-Ser-Phe-Glu-Val-Cys-Val-Pro-Lys-Thr-Pro-Lys-Thr (Disulfide bridge: Cys3-Cys18, Cys10-Cys23, Arg17-Cys33); L-alpha-glutamyl-L-alpha-aspartyl-L-cysteinyl-L-isoleucyl-L-prolyl-L-lysyl-L-tryptophyl-L-lysyl-glycyl-L-cysteinyl-L-valyl-L-asparagyl-L-arginyl-L-histidyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-glycyl-L-leucyl-L-alpha-glutamyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-arginyl-L-arginyl-L-arginyl-L-seryl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-cysteinyl-L-valyl-L-prolyl-L-lysyl-L-threonyl-L-prolyl-L-lysyl-L-threonine (3->18),(10->23),(17->33)-tris(disulfide). Grades: >98%. Molecular formula: C200H312N62O57S6. Mole weight: 4689.41.
Psalmotoxin 1
Psalmotoxin 1. Group: Biochemicals. Grades: Purified. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Psammaplin A
Antibiotic. Caffeine-like Ca2+ releaser in heavy sarcoplasmic reticulum (HSR). Antifungal. Chitinase inhibitor. DNA methyltransferase inhibitor. Histone deacetylase (HDAC) inhibitor. Anticancer compound. Angiogenesis suppressor. Group: Biochemicals. Alternative Names: (α E, α 'E) -N, N'- (Dithiodi-2, 1-ethanediyl) bis[3-bromo-4-hydroxy-α - (hydroxyimino) benzenepropanamide]; (E,E)-Psammaplin A; Bisprasin; Psammaplin A; UVI 5000; (E,E)-N,N'-(Dithiodi-2,1-ethanediyl)bis[3-bromo-4-hydroxy-α-(hydroxyimino)-benzenepropanamide]. Grades: Highly Purified. CAS No. 110659-91-1. Pack Sizes: 100ug, 500ug. Molecular Formula: C??H??Br?N?O?S?. US Biological Life Sciences.
Worldwide
Psammaplin A
Psammaplin A, a marine metabolite, is a potent inhibitor of HDAC and DNA methyltransferases. Group: Inhibitors. Alternative Names: Bisprasin. CAS No. 110659-91-1. Molecular formula: C22H24Br2N4O6S2. Mole weight: 664.4. Appearance: Solid. Purity: 95%+. IUPACName: (2E) -3- (3-Bromo-4-hydroxyphenyl) -N- [2- [2- [ [ (2E) -3- (3-bromo-4-hydroxyphenyl) -2-hydroxyiminopropanoyl] amino] ethyldisulfanyl] ethyl] -2-hydroxyiminopropanamide. Canonical SMILES: O=C (NCCSSCCNC (/C (CC1=CC (Br)=C (O)C=C1)=N/O)=O)/C (CC2=CC (Br)=C (O)C=C2)=N/O. Density: 1.72±0.1 g/cm³. Catalog: ACM110659911.
pSAS10
pSAS10 is an antimicrobial peptide found in seeds, cowpea, Vigna unguiculata, and has antifungal activity. Synonyms: Defensin-like protein (Clone PSAS10; Plant defensin). Grades: >98%. Molecular formula: C220H349N73O73S8. Mole weight: 5441.12.
PS-ATP Liposome
This product is a negatively charged ATP liposome. Adenosine triphosphate (ATP) is the direct energy source required for all cellular life activities. Encapsulating it within liposomes prevents enzymatic hydrolysis, prolongs circulation time, and significantly enhances its therapeutic efficacy. Due to the instability of ATP, this product is in the form of lyophilized powder. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
PSB 0474
PSB 0474. Group: Biochemicals. Grades: Purified. CAS No. 917567-60-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PSB 06126
PSB 06126. Group: Biochemicals. Grades: Purified. CAS No. 1052089-16-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PSB 06126
PSB 06126, an anthraquinone derivative, is a nucleoside triphosphate diphosphohydrolase 3 (NTPDase 3) inhibitor. It was reported to inhibit rat NTPDase 3 at low micromolar concentrations and display selectivity over NTPDase 1 and NTPDase 2. Synonyms: PSB 06126; PSB06126; PSB-06126;1-Amino-4-(1-naphthyl)aminoanthraquinone-2-sulfonic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 1052089-16-3. Molecular formula: C24H15N2NaO5S. Mole weight: 466.44.
PSB 069
PSB 069. Group: Biochemicals. Grades: Purified. CAS No. 78510-31-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 069
PSB 069 is a non-selective inhibitor of nucleoside triphosphate diphosphohydrolases 1,2,3 (NTPDases 1,2,3) (Ki = 15.7, 18.0, 16.4 μM, respectively). It was reported to inhibit rat NTPDases 1, 2 and 3 with similar potencies. Synonyms: PSB 069; PSB069; PSB-069; 1-Amino-4-(4-chlorophenyl)aminoanthraquinone-2-sulfonic acid sodium salt. Grades: ≥98% by HPLC. CAS No. 78510-31-3. Molecular formula: C20H12N2O5ClSNa. Mole weight: 450.83.
PSB 0739
PSB 0739 is a highly potent, direct-acting and reversible P2Y12 receptor antagonist (Ki = 24.9 nM). Unlike clopidogrel, it does not require bioactivation. P2Y12 receptors regulate CFA-induced hyperalgesia and the local inflammatory response, and platelet P2Y12 receptors contribute to these effects in the chronic inflammation phase. Synonyms: 1-Amino-9,10-dihydro-9,10-dioxo-4-[[4-(phenylamino)-3-sulfophenyl]amino]-2-anthracenesulfonic acid sodium salt; PSB-0739; PSB 0739; PSB0739 sodium. Grades: ≥95% by HPLC. CAS No. 1052087-90-7. Molecular formula: C26H17N3Na2O8S2. Mole weight: 609.54.
PSB 0777 ammonium salt
PSB 0777 ammonium salt. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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PSB 0777 ammonium salt
PSB 0777 is a potent adenosine A2A receptor full agonist (Ki = 44.4 nM for rat brain striatal A2A receptors), with subtype selectivity for A2A receptors over A1, A2B and A3 receptors (Ki ≥ 10 000 nM for rat A1, human A2B and human A3 receptors). The beneficial effects of PSB-0777 on inflammatory parameters were prevented by the pharmacological blockade of A2A receptors. No adverse cardiovascular events were observed upon PSB-0777 administration. The novel A2A receptor agonist PSB-0777 could represent the base for the development of innovative pharmacological entities able to act in an event-specific and site-specific manner. Synonyms: PSB 0777 ammonium salt; PSB0777 ammonium salt; PSB-0777 ammonium salt; 4-[2-[(6-Amino-9-b-D-ribofuranosyl-9H-purin-2-yl)thio]ethyl]benzenesulfonic acid ammonium salt. Grades: ≥98% by HPLC. CAS No. 2122196-16-9. Molecular formula: C18H20N5O7S2.NH4. Mole weight: 500.55.
PSB 0788
PSB 0788. Group: Biochemicals. Grades: Purified. CAS No. 1027513-54-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 0788
PSB 0788 is a selective A2B antagonist. Synonyms: PSB-0788; PSB 0788; PSB0788. 8-[4-[4-(4-Chlorobenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine. CAS No. 1027513-54-7. Molecular formula: C25H27ClN6O4S. Mole weight: 543.04.
PSB 10 hydrochloride
PSB 10 is a potent and highly selective antagonist for the human adenosine A3 receptor that displays > 17000-fold selectivity over other adenosine receptors (Ki values are 0.553, > 10000, > 10000 and > 10000 nM for A2B, A1, A2A and A3 receptors respectively). It produces thermal hyperalgesia in mice in vivo. Synonyms: PSB 10 hydrochloride; PSB10 hydrochloride; PSB-10 hydrochloride; 8-Ethyl-1,4,7,8-tetrahydro-4-methyl-2-(2,3,5-trichlorophenyl)-5H-imidazo[2,1-i]purin-5-one monohydrochloride. Grades: ≥98% by HPLC. CAS No. 591771-91-4. Molecular formula: C16H14Cl3N5O.HCl. Mole weight: 435.14.
PSB 10 hydrochloride
PSB 10 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 591771-91-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 1114
PSB 1114. Group: Biochemicals. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PSB 1114
PSB 1114, a β,γ-difluoromethylene derivative of 4-thio-UTP, is a potent, selective P2Y2 agonist (EC50 = 0.134 μM),with >60-fold selectivity versus P2Y4 and P2Y6 receptors. PSB 1114 activated P2Y2, P2Y4 and P2Y6 with EC50 values of 0.134, 9.3 and 7.0 μM respectively. Synonyms: 4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt; PSB1114; PSB 1114; PSB-1114. Grades: ≥98% by HPLC. CAS No. 1657025-60-9. Molecular formula: C10H11F2N2Na4O13P3S. Mole weight: 622.14.
PSB 1115
PSB 1115. Group: Biochemicals. Grades: Purified. CAS No. 152529-79-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 1115
PSB 1115 is a selective human A2B receptor antagonist. Synonyms: PSB1115; PSB-1115; Benzenesulfonic acid, 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-; 4-(2,3,6,9-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)benzenesulfonic acid; Benzenesulfonic acid, 4-(2,3,6,7-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-. Grades: ≥95%. CAS No. 152529-79-8. Molecular formula: C14H14N4O5S. Mole weight: 350.35.
PSB-1115 potassium salt
PSB-1115 is a highly selective antagonist of the adenosine A2B receptor with Ki value of 53.4 nM. Uses: Psb 1115 is an adenosine a2b-r antagonist. Synonyms: potassium;4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonate;trihydrate; potassium;4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonate;trihydrate. Grades: ≥ 98 %. CAS No. 409344-71-4. Molecular formula: C14H13N4O5SK. Mole weight: 388.44.
PSB 11 hydrochloride
PSB 11 hydrochloride, an anti-inflammatory imidazopurinone, has displayed potent and highly selective antagonist characteristics towards human Adenosine A3-R, with low affinity for the rat A3 receptor (Ki values are 2.3 and > 10000 nM respectively). It displays > 1000-fold selectivity over human A1 and A2A receptors (Ki values are 4.1 and 3.3 μM respectively) and > 180-fold selectivity over rat A1, rat A2A and mouse A2B receptors. Synonyms: 5H-Imidazo[2,1-i]purin-5-one, 8-ethyl-3,4,7,8-tetrahydro-4-methyl-2-phenyl-, hydrochloride (1:1), (8R)-; PSB11 hydrochloride; PSB-11 hydrochloride; (8R)-8-Ethyl-3,4,7,8-tetrahydro-4-methyl-2-phenyl-5H-imidazo[2,1-i]purin-5-one hydrochloride (1:1); 5H-Imidazo[2,1-i]purin-5-one, 8-ethyl-1,4,7,8-tetrahydro-4-methyl-2-phenyl-, monohydrochloride, (8R)-; (R)-8-ethyl-4-methyl-2-phenyl-7,8-dihydro-3H-imidazo[2,1-i]purin-5(4H)-one Hydrochloride. Grades: ≥98% by HPLC. CAS No. 453591-58-7. Molecular formula: C16H17N5O.HCl. Mole weight: 331.80.
PSB 11 hydrochloride
PSB 11 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 453591-58-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB-12062
PSB-12062 is a potent and selective P2X4 antagonist (IC50 = 1.38 μM for human P2X4) which has potential to be used as a therapeutic target for neutopathic pain, and treatment of traumatic brain injury, cerebral ischemia, and spinal cord injury. Synonyms: 10-(4-methylphenyl)sulfonylphenoxazine; N-(p-methylphenylsulfonyl)phenoxazine; PSB-12062; PSB 12062; PSB12062; 10-tosyl-10H-phenoxazine. CAS No. 55476-47-6. Molecular formula: C19H15NO3S. Mole weight: 337.39.
PSB 12379
PSB 12379, an α,β-Methylene-ADP (AOPCP) derivative, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). PSB-12379 displayed high selectivity versus other ecto-nucleotidases (NTPDase 1-3 and NPP 1-3) and ADP-activated P2Y (P2Y1 and P2Y12) receptors. PBS-12379 represents the most potent eN inhibitor known to date, showing high selectivity and metabolic stability. Synonyms: PSB12379; PSB-12379; N6-Benzyl-α,β-methyleneadenosine 5'-diphosphate; N6-benzyl-(alpha,beta)-methylene-ADP; (1-Deoxy-1-(6-benzylamino-9H-purine-9-yl)-beta-D-ribofuranose-5-O-yl)phosphonylmethylphosphonic acid; N-Benzyl-5'-O-[hydroxy (phosphonomethyl) phosphoryl]adenosine; N-(phenylmethyl)-adenosine, 5'-[hydrogen P-(phosphonomethyl)phosphonate]. Grades: ≥98% by HPLC. CAS No. 1802226-78-3. Molecular formula: C18H23N5O9P2. Mole weight: 515.35.
PSB 36
PSB 36. Group: Biochemicals. Grades: Purified. CAS No. 524944-72-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 36
PSB 36 is a potent and selective A1 adenosine receptor antagonist with binding affinities of 0.12, 187, 552, 6500 and 2300 nM for rA1, hA2B, rA2A, rA3 and hA3 receptors respectively. Synonyms: PSB 36; PSB36; PSB-36; 1-Butyl-8-(hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-3-(3-hydroxypropyl)-1H-purine-2,6-dione. Grades: ≥99% by HPLC. CAS No. 524944-72-7. Molecular formula: C21H30N4O3. Mole weight: 386.49.
PSB 603
PSB 603. Group: Biochemicals. Grades: Purified. CAS No. 1092351-10-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PSB 603
PSB 603 is a highly selective A2B antagonis. Synonyms: PSB603; PSB 603; PSB-603. 8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine. CAS No. 1092351-10-4. Molecular formula: C24H25ClN6O4S. Mole weight: 529.01.
PSB-603
PSB-603 is a potent and highly selective A 2B adenosine receptor antagonist exhibiting a K i value of 0.553 nM and virtually no affinity for the human and rat A 1 and A 2A and the human A 3 receptors up to a concentration of 10 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092351-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103166.
PSB-CB5
PSB-CB5 is a potent and selective antagonist of GRP18. PSB-CB5 has the potential for the research of metabolic disease and obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627710-30-8. Pack Sizes: 1 mg. Product ID: HY-44154.
PSB-SB1202
PSB-SB1202 is a benzylcoumarin compound that acts as an agonist of CB1 and CB2 receptors with EC50 values of 56 and 14 nM, respectively. Synonyms: 5-Methoxy-3-[(2-methoxyphenyl)methyl]-7-pentylchromen-2-one. Grades: ≥98%. CAS No. 1399049-60-5. Molecular formula: C23H26O4. Mole weight: 366.5.
PSBTBT
Flexible Printed Electronics. CAS No. 1089687-02-4. Purity: 0.96. Catalog: ACM1089687024.
PSC 833
PSC 833. Group: Biochemicals. Grades: Purified. CAS No. 121584-18-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PSCA (14-22)
PSCA (14-22) is amino acids 14 to 22 fragment of PSCA. Prostate Stem Cell Antigen is involved in the regulation of cell proliferation and has a cell-proliferation inhibition activity in vitro. Synonyms: Prostate Stem Cell Antigen (14-22).