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pyruvate kinase UTP, GTP, CTP, ITP and dATP can also act as donors. Also phosphorylates hydroxylamine and fluoride in the presence of CO2. Group: Enzymes. Synonyms: phosphoenolpyruvate kinase; phosphoenol transphosphorylase. Enzyme Commission Number: EC 2.7.1.40. CAS No. 9001-59-6. Pyruvate Kinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3070; pyruvate kinase; EC 2.7.1.40; 9001-59-6; phosphoenolpyruvate kinase; phosphoenol transphosphorylase. Cat No: EXWM-3070. Creative Enzymes
Pyruvate Kinase Activator (N-(4-Chloro-3-fluorophenyl)-7-fluoro-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide, PKM2 Activator I) A cell-permeable and biologically stable (t1/2 = 277.2 and 117.5 min., respectively, in human and mouse liver microsome preparation) tetrahydroquinoline-sulfonamide that enhances the donor PEP, but not the acceptor ADP, substrate affinity toward pyruvate kinase isoform PKM2 (Km = 0.4 vs. 1.9 mM with or without 10uM activator) and acts as a potent PKM2-selective activator (AC50 = 90nM using rhPKM2; ACmax = 88%), displaying much reduced activity toward PKL (<25% at 57uM) and no effect toward PKM1 or PKR. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??ClF?N?O?S, Molecular Weight: 372.8. US Biological Life Sciences. USBiological 13
Worldwide
Pyruvate Kinase from Microorganism Pyruvate kinase is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP. Group: Enzymes. Synonyms: EC 2.7.1.40; 9001-59-6; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase. Enzyme Commission Number: EC 2.7.1.40. CAS No. 9001-59-6. Mole weight: 68 kDa (SDS-PAGE). Activity: >300U/mg. Storage: Store at -20°C. Form: White powder, lyophilized. Source: Microorganism. Pyruvate kinase; EC 2.7.1.40; 9001-59-6; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase; PK. Cat No: NATE-1720. Creative Enzymes
Pyruvate kinase M2 Active from Mouse, Recombinant Pyruvate kinase M2 (PKM2) is an isoform of pyruvate kinase that is expressed in certain differentiated cells and in proliferatively active cells. PKM2 is often overexpressed in cancer cells. Group: Enzymes. Synonyms: M2-PK tumor; OPA-interacting protein 3 (OIP-3); Pyruvate kinase 3 (PK3); Pyruvate kinase; muscle; Thyroid hormone-binding protein 1 (THBP1); Pyruvate kinase; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase. CAS No. 9001-59-6. Purity: Greater than 90% (SDS-PAGE). Pyruvate Kinase. Mole weight: 58 kDa. Storage: Store at -70°C. Avoid multiple freeze-thaw cycles. Form: Aqueous solution, Formulated in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol and 3 mM DTT. Source: E. coli. Species: Mouse. M2-PK tumor; OPA-interacting protein 3 (OIP-3); Pyruvate kinase 3 (PK3); Pyruvate kinase; muscle; Thyroid hormone-binding protein 1 (THBP1); Pyruvate kinase; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase. Cat No: NATE-0939. Creative Enzymes
Pyruvate Kinase M2 from Human, Recombinant Pyruvate kinase (PK) is an important glycolytic enzyme catalyzing the last step of glycolysis, transferring a phosphate group from phosphoenolpyruvate to ADP to yield one molecule of ATP and one molecule of pyruvate. Group: Enzymes. Synonyms: Cytosolic Thyroid hormone-binding protein (CTHBP); M2-PK; OPA-interacting protein 3 (OIP-3); PKM2; Pyruvate kinase 3 (PK3); Pyruvate kinase muscle isozyme; p58; Pyruvate kinase; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase. CAS No. 9001-59-6. Pyruvate Kinase. Mole weight: 58 kDa. Activity: > 100 unit/μg protein. Storage: Store at -20°C. Form: Lyophilized powder containing phosphate buffer at pH7.5, NaCl, DTT and a carbohydrate stabilizer. Source: E. coli. Species: Human. Cytosolic Thyroid hormone-binding protein (CTHBP); M2-PK; OPA-interacting protein 3 (OIP-3); PKM2; Pyruvate kinase 3 (PK3); Pyruvate kinase muscle isozyme; p58; Pyruvate kinase; phosphoenolpyruvate kinase; phosphoenol transphosphorylase; pyruvate kinase (phosphorylating); fluorokinase; fluorokinase (phosphorylating); pyruvic kinase; pyruvate phosphotransferase; ATP:pyruvate 2-O-phosphotransferase. Cat No: NATE-0938. Creative Enzymes
pyruvate oxidase A flavoprotein (FAD) requiring thiamine diphosphate. Two reducing equivalents are transferred from the resonant carbanion/enamine forms of 2-hydroxyethyl-thiamine-diphosphate to the adjacent flavin cofactor, yielding 2-acetyl-thiamine diphosphate (AcThDP) and reduced flavin. FADH2 is reoxidized by O2 to yield H2O2 and FAD and AcThDP is cleaved phosphorolytically to acetyl phosphate and thiamine diphosphate. Group: Enzymes. Synonyms: pyruvic oxidase; phosphate-dependent pyruvate oxidase. Enzyme Commission Number: EC 1.2.3.3. CAS No. 9001-96-1. Pyruvate oxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1210; pyruvate oxidase; EC 1.2.3.3; 9001-96-1; pyruvic oxidase; phosphate-dependent pyruvate oxidase. Cat No: EXWM-1210. Creative Enzymes
pyruvate oxidase (CoA-acetylating) A flavoprotein (FAD). May be identical with EC 1.2.7.1 pyruvate synthase. Group: Enzymes. Enzyme Commission Number: EC 1.2.3.6. CAS No. 62213-57-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1213; pyruvate oxidase (CoA-acetylating); EC 1.2.3.6; 62213-57-4. Cat No: EXWM-1213. Creative Enzymes
Pyruvate Oxidase from E.coli, Recombinant Recombinant oxidoreductase that catalyzes the interconversion of pyruvate to acetyl phosphate. Rely in the proven diagnostic quality of this product. Applications: Use pyruvate oxidase in a variety of diagnostic tests, such as for the determination of pyruvate, lactate or aminotransferases. Group: Enzymes. Synonyms: pyruvic oxidase; phosphate-dependent pyruvate oxidase; Pyruvate:oxygen oxidoreductase (phosphorylating); PoxB. CAS No. 9001-96-1. Pyruvate oxidase. Activity: >1.5 U/mg lyophilizate; >3 U/mg protein. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Appearance: Yellow lyophilizate. Source: E. coli. pyruvate oxidase; EC 1.2.3.3; pyruvic oxidase; phosphate-dependent pyruvate oxidase; 9001-96-1; Pyruvate:oxygen oxidoreductase (phosphorylating); PoxB. Cat No: DIA-289. Creative Enzymes
Pyruvate Oxidase, Microorganisms Pyruvate Oxidase, Microorganisms (PoxB) is a peripheral membrane enzyme, isolated from microorganisms. Pyruvate oxidase catalyzes the oxidative decarboxylation of pyruvate to acetyl phosphate, carbon dioxide and water. Pyruvate oxidase is an important enzyme in bacterial metabolism and is often used in biochemical research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PoxB. CAS No. 9001-96-1. Pack Sizes: 100 U. Product ID: HY-P2891. MedChemExpress MCE
pyruvate, phosphate dikinase It is a key enzyme in gluconeogenesis and photosynthesis that is responsible for reversing the reaction performed by pyruvate kinase in Embden-Meyerhof-Parnas glycolysis. Group: Enzymes. Synonyms: pyruvate, orthophosphate dikinase; pyruvate-phosphate dikinase (phosphorylating); pyruvate, phosphate dikinase; pyruvate-inorganic phosphate dikinase; pyruvate-phosphate dikinase; pyruvate-phosphate ligase; pyruvic-phosphate dikinase; pyruvic-phosphate ligase; pyruvate, Pi dikinase; PPDK. Enzyme Commission Number: EC 2.7.9.1. CAS No. 9027-40-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3348; pyruvate, phosphate dikinase; EC 2.7.9.1; 9027-40-1; pyruvate, orthophosphate dikinase; pyruvate-phosphate dikinase (phosphorylating); pyruvate, phosphate dikinase; pyruvate-inorganic phosphate dikinase; pyruvate-phosphate dikinase; pyruvate-phosphate ligase; pyruvic-phosphate dikinase; pyruvic-phosphate ligase; pyruvate, Pi dikinase; PPDK. Cat No: EXWM-3348. Creative Enzymes
pyruvate synthase Contains thiamine diphosphate and [4Fe-4S] clusters. The enzyme also decarboxylates 2-oxobutyrate with lower efficiency, but shows no activity with 2-oxoglutarate. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.3, 2-oxoglutarate synthase and EC 1.2.7.7, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). Group: Enzymes. Synonyms: pyruvate oxidoreductase; pyruvate synthetase; pyruvate:ferredoxin oxidoreductase; pyruvic-ferredoxin oxidoreductase; 2-oxobutyrate synthase; &. Enzyme Commission Number: EC 1.2.7.1. CAS No. 9082-51-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1223; pyruvate synthase; EC 1.2.7.1; 9082-51-3; pyruvate oxidoreductase; pyruvate synthetase; pyruvate:ferredoxin oxidoreductase; pyruvic-ferredoxin oxidoreductase; 2-oxobutyrate synthase; α-ketobutyrate-ferredoxin oxidoreductase; 2-ketobutyrate synthase; α-ketobutyrate synthase; 2-oxobutyrate-ferredoxin oxidoreductase; 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating); 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating). Cat No: EXWM-1223. Creative Enzymes
pyruvate, water dikinase A manganese protein. Group: Enzymes. Synonyms: phosphoenolpyruvate synthase; pyruvate-water dikinase (phosphorylating); PEP synthetase; phosphoenolpyruvate synthase; phoephoenolpyruvate synthetase; phosphoenolpyruvic synthase; phosphopyruvate synthetase. Enzyme Commission Number: EC 2.7.9.2. CAS No. 9013-9-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3349; pyruvate, water dikinase; EC 2.7.9.2; 9013-09-6; phosphoenolpyruvate synthase; pyruvate-water dikinase (phosphorylating); PEP synthetase; phosphoenolpyruvate synthase; phoephoenolpyruvate synthetase; phosphoenolpyruvic synthase; phosphopyruvate synthetase. Cat No: EXWM-3349. Creative Enzymes
Pyruvic-1-13C acid (free acid) Pyruvic-1-13C acid (free acid). Alternative Names: Pyruvic acid-1-13C, 13C Labeled pyruvic acid, 2-Oxopropionic acid-1-13C, |A-Ketopropionic acid-1-13C, Pyruvic-1-13C acid (free acid), 99124-30-8. CAS No. 99124-30-8. Purity: 99%+. Product ID: ACM99124308. Molecular formula: CH3CO13CO2H. Mole weight: 89.05. IUPAC Name: 2-oxopropanoic acid. Canonical SMILES: CC(=O)C(=O)O. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry.
Pyruvic-3-13c acid sodium salt Pyruvic-3-13c acid sodium salt. CAS No. 124052-04-6. Product ID: ACM124052046. Molecular formula: C3H3NaO3. Mole weight: 111.05. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 3
Pyruvic acid Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acetylformic acid. CAS No. 127-17-3. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-Y0781. MedChemExpress MCE
Pyruvic acid 500g Pack Size. Group: Analytical Reagents, Aroma Chemicals, Biochemicals, Carbohydrates. Formula: CH3COCOOH. CAS No. 127-17-3. Prepack ID 28177601-500g. Molecular Weight 88.06. See USA prepack pricing. Molekula Americas
Pyruvic Acid Pyruvic Acid. Group: Biochemicals. Alternative Names: 2-Oxopropanoic Acid; Pyruvate; α-Ketopropionate. Grades: Highly Purified. CAS No. 127-17-3. Pack Sizes: 50g. Molecular Formula: C3H4O3, Molecular Weight: 88.06. US Biological Life Sciences. USBiological 13
Worldwide
Pyruvic Acid Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH3COCOO-, is an intermediate in several metabolic pathways throughout the cell. Alternative Names: α-Ketopropionic acid. CAS No. 127-17-3. Purity: 99%. Product ID: FFC127173. Molecular formula: C3H4O3. Mole weight: 88.06. IUPAC Name: 2-Oxopropanoic acid. Canonical SMILES: CC(=O)C(=O)O. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry.
Pyruvic acid-[1-13C] Pyruvic acid-[1-13C] is a labelled analogue of Pyruvic Acid which can be reduced to lactic acid during exertion, reoxidized at rest and partially converted to glycogen in muscles. Pyruvic Acid is also used as a diagnostic agent for Parkinson's disease. Synonyms: α-Ketopropionic acid-1-13C; 2-Oxopropionic acid-1-13C; 13C-Pyruvic acid. Grade: ≥99% by CP; ≥99% atom 13C. CAS No. 99124-30-8. Molecular formula: C2[13C]H4O3. Mole weight: 89.05. BOC Sciences 2
Pyruvic acid-13C3 sodium Sodium 2-oxopropanoate-13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium 2-oxopropanoate-13C3; Acetylformic acid-13C3 sodium. CAS No. 142014-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W015913S. MedChemExpress MCE
Pyruvic acid-13c,d3 sodium salt Pyruvic acid-13c,d3 sodium salt. Alternative Names: 2-Oxopropanoic Acid-13C,d3 Sodium Salt; Sodium Pyruvate-13C,d3; Sodium α-Ketopropionate-13C,d3. CAS No. 1215831-74-5. Purity: 96%. Product ID: ACM1215831745. Molecular formula: C213CD3NaO3. Mole weight: 114.06. IUPAC Name: sodium;3,3,3-trideuterio-2-oxopropanoate. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 3
Pyruvic Acid-[13C,d3] Sodium Salt Pyruvic Acid-[13C,d3] Sodium Salt. Uses: Labelled pyruvic acid. a diagnostic agent for parkinson disease. Synonyms: Pyruvic Acid 13C,d3 Sodium Salt; Sodium 2-oxo(3-13C,2H3)propanoate. Grade: 95% atom D; 95% atom 13C. CAS No. 1215831-74-5. Molecular formula: C2[13C]D3NaO3. Mole weight: 114.06. BOC Sciences 2
Pyruvic Acid Calcium Salt Pyruvic Acid Calcium Salt. Alternative Names: Propanoic acid, 2-oxo-, calcium salt, hydrate (2:5). CAS No. 17070-07-4. Product ID: ACM17070074. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 4
Pyruvic acid ethyl ester Pyruvic acid ethyl ester. Group: Biochemicals. Alternative Names: 2-Oxopropanoic acid ethyl ester; 2-Oxopropionic acid ethyl ester; Ethyl 2-oxopropanoate. Grades: Highly Purified. CAS No. 617-35-6. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C5H8O3. US Biological Life Sciences. USBiological 13
Worldwide
Pyruvic acid sodium Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sodium 2-oxopropanoate; Acetylformic acid sodium. CAS No. 113-24-6. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W015913. MedChemExpress MCE
Pyruvic aldehyde (40%w/w in water) Pyruvic aldehyde (40%w/w in water) is a cell stabilizer. Pyruvic aldehyde (40%w/w in water) can be used for stabilization of cells, such as erythrocytes. Pyruvic aldehyde (40%w/w in water) can be efficiently catalyzed to Lactic acid (HY-B2227) by a Lewis acid catalyst[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 78-98-8. Pack Sizes: 1 mL; 5 mL. Product ID: HY-W020014. MedChemExpress MCE
Pyruvic aldehyde dimethyl acetal Pyruvic aldehyde dimethyl acetal. Alternative Names: 1,1-Dimethoxyacetone. CAS No. 6342-56-9. Purity: >97.0%. Product ID: FFC-AR-6342569. Molecular formula: C5H10O3. Mole weight: 118.13. IUPAC Name: 1,1-dimethoxypropan-2-one. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry.
Pyruvic aldehyde dimethyl Acetal, 97+% Pyruvic aldehyde dimethyl Acetal, 97+%. CAS No: 6342-59-9 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
Pyruvonitrile Pyruvonitrile. CAS No: 631-57-2 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
Pyrvinium Pyrvinium. Group: Biochemicals. Alternative Names: 4-[(3-carboxylato-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylate. Grades: Highly Purified. CAS No. 7187-62-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C75H70N6O6. US Biological Life Sciences. USBiological 13
Worldwide
Pyrvinium pamoate Pyrvinium pamoate is an FDA-approved antihelmintic agent that inhibits WNT pathway signaling. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pyrvinium embonate. CAS No. 3546-41-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0293. MedChemExpress MCE
Pyrvinium Pamoate Pyrvinium Pamoate is a potent noncompetitive inhibitor of the androgen receptor, with the application towards prostate cancer treatment. Antihelmintic. Group: Biochemicals. Alternative Names: Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4 -Methylenebis[3-hydroxy-2-naphthoate]]; 6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-Quinolinium, Salt with 4,4 -Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid] (2:1); 6-(dimM6thylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methyl-Quinoliniussalt with 4,4 -Methylenebis[3-hydroxy-2-naphthoic Acid] (2:1); bis[6-(Dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylquinolinium] 4,4 -Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid on(2-); Bis[6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium] 4,4 -Methylenebis[3-hydroxy-2-naphthoic Acid ion(2-); 6-Dimethylamino-2-[2-(2,5-dimethyl-1-p. CAS No. 3546-41-6. Pack Sizes: 500mg. Molecular Formula: C23H14O6 2[C26H28N3], Molecular Weight: 1151.39. US Biological Life Sciences. USBiological 13
Worldwide
Pyxinol Pyxinol is the main metabolite of 20S-protopanaxadiol in the human liver. Synonyms: Pixinol; Dammarane-3β,12β,25-triol, 20,24-epoxy-, (20R,24S)- (8CI); (3β,12β,20R,24S)-20,24-Epoxydammarane-3,12,25-triol. CAS No. 25330-18-1. Molecular formula: C30H52O4. Mole weight: 476.73. BOC Sciences 12
PYZD 4409 PYZD 4409. Group: Biochemicals. Grades: Purified. CAS No. 423148-78-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
PYZD-4409 PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 423148-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13297. MedChemExpress MCE
PZ-128 PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: P1pal-7. CAS No. 371131-16-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107146. MedChemExpress MCE
PZ-2891 PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170608-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124634. MedChemExpress MCE
PZ703b PZ703b is a Bcl-xl PROTAC degrader that induces apoptosis and inhibits cancer cell proliferation. PZ703b can be used for the research of bladder cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2471970-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-115718. MedChemExpress MCE
PZL-A PZL-A is a activator of mitochondrial DNA (mtDNA) synthesis. PZL-A restores wild-type-like activity to mutant forms of polymerase γ (POLγ) with AC50 s of 160 and 20 nM for A467T and G848S. PZL-A activates mtDNA synthesis in cells, enhancing biogenesis of the oxidative phosphorylation machinery and cellular respiration. PZL-A is promising for relieving POLG disease and other severe conditions linked to depletion of mtDNA[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3068830-89-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174216. MedChemExpress MCE
PZM21 PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1997387-43-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101386. MedChemExpress MCE
PZ-Peptide PZ-Peptide is a chromogenic substrate for the assay of collagenase and thimet oligopeptidase (Pz-peptidase, metalloendopeptidase 24.15, collagenase-like peptidase). Synonyms: 4-Phenylazobenzyloxycarbonyl-L-pro-leu-gly-pro-D-arg dihydrate; Pz-Cpz-Pro-Leu-Gly-Pro-Arg. CAS No. 17011-78-8. Molecular formula: C38H52N10O8. Mole weight: 776.88. BOC Sciences 11

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