A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Petitgrain Oil. CAS No. 8016-44-2. Kosher: Y. VIGON Item # 504227. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Petitgrain Oil Terpeneless
Petitgrain Oil Terpeneless. CAS No. 68915-85-5. Kosher: Y. VIGON Item # 504054. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics.
America & Internationally
PET Media Bottles
PET Media Bottles. Product ID: PM-048. Product Keywords: Packaging Materials; Plastic Packaging; PM-048; PET Media Bottles.
Petosemtamab
Petosemtamab (MCLA 158) is an anti- EGFR (Kd: 0.22 nM) and anti-LGR5 (Kd: 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCLA 158. CAS No. 2213450-26-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99406.
PE travel plastic packaging bottle
This package is suitable for shampoo, body wash, conditioner, body lotion, facial mask, hair wax, etc. Product ID: PM-080. Category: PE bottle. Product Keywords: Cosmetic Plastic Packaging; PE travel plastic packaging bottle; PM-080; PE bottle;. Administration route: The color and size can be customized according to the customer's needs.
PET Ready to Use Vials
PET Ready to Use Vials. Product ID: PM-050. Product Keywords: Packaging Materials; Plastic Packaging; PM-050; PET Ready to Use Vials.
Petrelintide
Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZP8396. CAS No. 2766385-23-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10745.
Petri dishes, polystyrene
Petri dishes, polystyrene.
Petroleum Ether
Petroleum Ethers are used in the analysis of varnishes. Group: Biochemicals. Grades: Highly Purified. CAS No. 8032-32-4. Pack Sizes: 50ml, 100ml. Molecular Formula: N/A, Molecular Weight: US Biological Life Sciences.
Worldwide
Petroleum Ether
Petroleum Ether. CAS No. 8032-32-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Petroleum ether 40-60
1lt Pack Size. Group: Building Blocks, Organics, Solvents. Formula: N/A. CAS No. 8032-32-4. Prepack ID 89992871-1lt. See USA prepack pricing.
Petroleum Hydrocarbon Resin C9
Petroleum Hydrocarbon Resin C9. CAS No. 64742-16-1.
Petroleum jelly
Petroleum jelly is a semi-solid mixture of hydrocarbons. CAS No. 8009-3-8. Product ID: CDC10-0488. Category: Moisturizers. Product Keywords: Cosmetic Ingredients; Moisturizers; Petroleum jelly; CDC10-0488; 8009-03-8; 232-373-2; MFCD00147839; 8009-03-8. EC Number: 232-373-2. Solubility: water: insoluble. Quality Level: 200.
Petroleum Jelly
Petroleum Jelly. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
US and Canada
Petroleum Jelly
Petroleum Jelly. Market: Food Additives / Preservatives, Cosmetics & Personal Care. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
Petroleum Jelly 3/8/09
Petroleum Jelly 3/8/09. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Petroleum Jelly 8003-03-8
Petroleum Jelly - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Petroleum resin C9 64742-16-1
Petroleum resin C9 - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Petroleum resins
Petroleum resins. Alternative Names: Petrolium Resin;Resins, petroleum;Petroleum resins;hydrocarbon resin, postpolymerised with maleic anhydride. CAS No. 64742-16-1.
Petromurin C
Petromurin C is a metabolite isolated as a component of bis-indolyl benzenoid complex from Aspergillus muricatus. It exhibits antitumor activity. Synonyms: 1H-Indol-5-ol, 3-[4-(1H-indol-3-yl)-2,3,5,6-tetramethoxyphenyl]-. Grade: ≥95%. CAS No. 194608-29-2. Molecular formula: C26H24N2O5. Mole weight: 444.48.
Petromyzonol
Petromyzonol. Group: Biochemicals. Alternative Names: 5-a-Cholane-3-a,7-a,12-a,24-tetrol; (3a,5a,7a,12a)Cholane-3,7,12,24-tetrol. Grades: Highly Purified. CAS No. 28979-29-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H42O4. US Biological Life Sciences.
Worldwide
Petromyzonol 24 Hemisuccinate
Petromyzonol 24 Hemisuccinate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Petromyzonol-24-Sulfate, Sodium Salt (PZS)
Petromyzonol sulfate (PZS) is a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). PZS appears to be a spawning chemoattractant for the sea lamprey. Group: Biochemicals. Alternative Names: PZS. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
petromyzonol sulfotransferase
The enzyme from the lamprey Petromyzon marinus can also use the corresponding 3-ketone as a substrate. It is stereoselective (5α-cholane) and regioselective, exhibiting a preference for an hydroxy group at C-24. The enzyme is inactive when allocholic acid, which has a carboxy group at C-24, is used as a substrate. Group: Enzymes. Synonyms: PZ-SULT. Enzyme Commission Number: EC 2.8.2.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3391; petromyzonol sulfotransferase; EC 2.8.2.31; PZ-SULT. Cat No: EXWM-3391.
Petro Resin
Petro Resin.
Petroselinic acid
Petroselinic acid. Alternative Names: (Z)-Octadec-6-enoate. CAS No. 593-39-5. Molecular formula: C18H34O2. Mole weight: 282.46. Purity: 99%. SMILES: CCCCCCCCCCC/C=C\CCCCC(=O)O. InChI: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h12-13H,2-11,14-17H2,1H3,(H,19,20)/b13-12-.
PET Sirop Bottles
PET Sirop Bottles. Product ID: PM-043. Product Keywords: Packaging Materials; Plastic Packaging; PM-043; PET Sirop Bottles.
PET Tablet Bottles
PET Tablet Bottles. Product ID: PM-042. Product Keywords: Packaging Materials; Plastic Packaging; PM-042; PET Tablet Bottles.
PET Therapy Bottles-Clear, Amber White or Black
PET Therapy Bottles-Clear, Amber White or Black. Product ID: PM-049. Product Keywords: Packaging Materials; Plastic Packaging; PM-049; PET Therapy Bottles-Clear, Amber White or Black.
Petunidin-3-O-arabinoside chloride
Petunidin-3-O-arabinoside chloride is an anthocyanin with antioxidant activity that can be isolated from blueberry (Vaccinium Spp.) puree[1]. Uses: Scientific research. Category: Natural products. CAS No. 28500-03-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126409.
Petunidin-3-O-glucoside chloride
Petunidin-3-O-glucoside chloride is a flavonoid isolated from Phaseolus vulgaris L. seed, has antioxidant activity[1]. Uses: Scientific research. Category: Natural products. CAS No. 6988-81-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7832.
Petunidin-3-(p-coumaroyl-rutinoside)-5-glucoside
Petunidin-3-(p-coumaroyl-rutinoside)-5-glucoside is an anthocyanin that can be isolated from potatoes (Solanum tuberosum L.)[1]. Uses: Scientific research. Category: Natural products. CAS No. 30678-24-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12574.
Petunidin chloride
Petunidin chloride is an O-methylated anthocyanidin derived from delphinidin. Petunidin chloride binds with and suppresses the activity of focal adhesion kinase and to inhibit platelet-derived growth factor-induced aortic smooth muscle cell migration, which may confer a protective effect against atherosclerosis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1429-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126410.
Petunidin (chloride)
Petunidin (chloride). Alternative Names: Petunidol. CAS No. 1429-30-7. Purity: >98.0%. Product ID: FFC-AR-1429307. Molecular formula: C16H13O7Cl. Mole weight: 352.72. IUPAC Name: 2-(3,4-dihydroxy-5-methoxyphenyl)chromenylium-3,5,7-triol chloride. Alfa Chemistry - ISO 9001:32057 Certified.
Peturadol
NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HTS 09836; NB001. CAS No. 686301-48-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14425.
Peucedanol
Peucedanol is an intriguing biologically active constituent originating from the diverse Peucedanum plants, aiding in studying inflammation encompassing rheumatoid arthritand asthma. Synonyms: 6-[(2R)-2,3-dihydroxy-3-methylbutyl]-7-hydroxychromen-2-one. Grade: 98.5%. CAS No. 20516-23-8. Molecular formula: C14H16O5. Mole weight: 264.277.
Peucedanol
Peucedanol. Group: Biochemicals. Alternative Names: Ohter Cas No, 20126-72-1. Grades: Plant Grade. CAS No. 20516-23-8. Pack Sizes: 10mg. Molecular Formula: C14H16O5, Molecular Weight: 264.274. US Biological Life Sciences.
Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Pevonedistat induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat suppresses the growth of human tumour xenografts in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MLN4924. CAS No. 905579-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-70062.
Pevonedistat hydrochloride
Pevonedistat (MLN4924) hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. Pevonedistat hydrochloride induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat hydrochloride suppresses the growth of human tumour xenografts in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MLN4924 hydrochloride. CAS No. 1160295-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10484.
Pevonedistat (Standard)
Pevonedistat (Standard) is the analytical standard of Pevonedistat. This product is intended for research and analytical applications. Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Pevonedistat induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat suppresses the growth of human tumour xenografts in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MLN4924 (Standard). CAS No. 905579-51-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-70062R.
PE wax
PE wax.
Pexacerfont
Pexacerfont is a selective corticotropin-releasing factor (CRF1) receptor antagonist with IC50 of 6.1±0.6 nM for human CRF1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-562086. CAS No. 459856-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12127.
Pexidartinib
Pexidartinib (PLX-3397) is a capsule containing a small-molecule receptor tyrosine kinase (RTK) inhibitor targeting KIT, CSF1R, and FLT3, with potential antineoplastic activity. Category: Active pharmaceutical ingredients. CAS No. 1029044-16-3. Product ID: API1029044163. Molecular formula: C20H15ClF3N5. Mole weight: 417.81.
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity. Pexidartinib has limited permeability to the blood-brain barrier, primarily through ABCB1[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLX-3397. CAS No. 1029044-16-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749.
Pexidartinib hydrochloride
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLX-3397 hydrochloride. CAS No. 2040295-03-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g; 10 g; 20 g. Product ID: HY-16749A.
Pexidartinib hydrochloride
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally active, ATP-competitive inhibitor of colony-stimulating factor 1 (CSF1R or M-CSFR) (IC50: 20 nM) and c-Kit (IC50: 10 nM), with 10-100 times greater selectivity for these targets compared to FLT3 (IC50: 160 nM), KDR (VEGFR2) (IC50: 350 nM), and LCK (IC50: 860 nM). Pexidartinib hydrochloride induces apoptosis and exhibits anti-tumor effects. Category: Active pharmaceutical ingredients. CAS No. 2040295-03-0. Product ID: API2040295030. Molecular formula: C20H16Cl2F3N5. Mole weight: 454.28.
Pexidartinib (PLX3397)
Pexidartinib (PLX3397) is an oral, potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit (c-Kit), and FLT3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Pexidartinib (PLX3397) induces apoptosis and necrosis with antitumor activity. Phase 3. Group: Inhibitors. CAS No. 1029044-16-3. Pack Sizes: 10mg. Product ID: S7818. Formula: C20H15ClF3N5. Smiles: C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Pexiganan
Pexiganan (MSI 78) is an orally active antimicrobial peptide with broad-spectrum bactericidal. Pexiganan disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis. Pexiganan TFA can be used for the research of bacterial infection[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSI 78 free base. CAS No. 147664-63-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105088.
Pexiganan
An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Grade: >95%. CAS No. 147664-63-9. Molecular formula: C122H209N31O23. Mole weight: 2478.19.
Pexiganan acetate
An antimicrobial peptide (AMP) that is effective against a broad spectrum of bacteria including aerobic and anaerobic, gram-positive and gram-negative. Synonyms: MSI 78; Pexiganan. Grade: >98%. CAS No. 172820-23-4. Molecular formula: C122H210N32O22.C2H4O2. Mole weight: 2537.22.
Pexmetinib
Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38α and p38β, respectively, and can be used in the research of acute myeloid leukemia. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARRY-614. CAS No. 945614-12-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16782.
PF-00446687 free base
PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12?±?1 nM[1]. Pf-446687 is brain penetrant[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862281-92-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10622.
PF-00835231
PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is developed for the research of anti-SARS-CoV-2/COVID-19. PF-00835231 can inhibit cell infections and also suppress infections in animal models[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 870153-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137048.
PF-01247324
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker with an IC50 of 196 nM for recombinant human Nav1.8 channel. Uses: Scientific research. Category: Signaling pathways. CAS No. 875051-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101383.
PF-02341066 (Crizotinib)
Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM in cell-based assays, respectively. It is also a potent ROS1 inhibitor with Ki value less than 0.025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Group: Inhibitors. Alternative Names: PF-02341066. CAS No. 877399-52-5. Pack Sizes: 5mg. Product ID: S1068. Formula: C21H22Cl2FN5O. Smiles: CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
PF-03715455
PF-03715455 is a potent inhaled p38 MAPK inhibitor. PF-03715455 shows some selectivity for p38α over p38β with respective IC50 values of 0.88 and 23 nM. PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 has potential for the treatment of COPD (chronic obstructive pulmonary disease)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1056164-52-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18862.
PF 03814735
PF 03814735 is an orally bioavailable small molecule aurora kinase inhibitor that plays a key role in the regulation of mitosis. PF 03814735 is a anticancer agent used for cancer therapy. Group: Biochemicals. Alternative Names: N-[2-[(1S,4R)-6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]-acetamide. Grades: Highly Purified. CAS No. 942487-16-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PF-03814735
PF-03814735 is a potent, orally available, ATP-competitive and reversible aurora A and aurora B inhibitor with IC50s of 0.8 and 0.5 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 942487-16-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14574.
PF-04418948
PF-04418948, a chemical probe, is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1078166-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18966.
PF-04449613
PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM[1]. PF-04449613 improved motor learning ability in a mouse model[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1236858-52-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12788.
PF 04531083
PF 04531083 is an orally active and selective NaV1.8 blocker with an IC50 of 0.7 μM. PF 04531083 is a blood-brain barrier (BBB) penetrant compound. PF 04531083 can be used for the research of respiratory system and neuropathic/inflammatory pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1079400-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105283.
PF-04620110
PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC50 of 19 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1109276-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13009.
PF-04628935
PF-04628935 (compound 10n) is a potent ghrelin receptor inverse agonist, with an IC50 of 4.6 nM. PF-04628935 exhibits oral bioavailability of 43% in rats and shows reasonable penetration into the brain. PF-04628935 can be used for stress and anxiety research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1383719-97-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-116625.
PF-04634817 succinate
PF-0463481 succinate is a potent and orally active dual CCR2/CCR5 antagonist with comparable human and rodent CCR2 potency (rat IC50=20.8 nM), and displays 10-20 fold less rodent CCR5 potency (rat IC50=470 nM). PF-0463481 succinate is safe and well-tolerated and has the potential for the study of diabetic nephropathy[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140301-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-117621A.
PF-04691502
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR. PF-04691502 binds to human PI3Kα, β, δ, γ and mTOR with Kis of 1.8, 2.1, 1.6, 1.9 and 16 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1013101-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15177.
PF-04745637
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1917294-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120689.
PF-04856264
PF-04856264 is a potent and selective Nav1.7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1.7, respectively. PF-04856264 has low potency against the rat Nav1.7 channel. PF-04856264 shows analgesic effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1235397-05-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12811.