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| Product | Description | |
|---|---|---|
| PF184 | PF184. CAS No: 1187460-81-6 |  Sarchem Laboratories New Jersey NJ |
| PF 184 | PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1 β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress. Group: Biochemicals. Alternative Names: 8- [ [ [5-Chloro-2- [3, 4-dimethyl-3, 4-bis (hydroxymethyl) -1-pyrrolidinyl] -4-pyridinyl] carbonyl] amino] -1- (4-fluorophenyl) -4, 5-dihydro-1H-benz [g] indazole-3-carboxamide. Grades: Highly Purified. CAS No. 1187460-81-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PF2EH | PF2EH. Alternative Names: POLY(9 9-BIS-(2-ETHYLHEXYL)-9H-FLUORENE&;POLY(9,9-DI-(2-ETHYLHEXYL)FLUORENYL-2,&;Poly[9,9-di-(2-ethylhexyl)fluorenyl-2,7-diyl];Poly[9,9-bis-(2-ethylhexyl)-9H-fluorene-2,7-diyl];Poly[9,9-bis(2-ehtylhexyl)fluorenyl-2,7-diyl];Poly[9,9-bis-(2-ethylhexyl)-9H-f. CAS No. 188201-16-3. Molecular formula: C22H18Cl2N2O5S. Mole weight: 493.4g/mol. IUPAC Name: (2-amino-2-oxoethyl) 3-[benzyl-(4-chlorophenyl)sulfamoyl]-4-chlorobenzoate. SMILES: C1=CC=C(C=C1)CN(C2=CC=C(C=C2)Cl)S(=O)(=O)C3=C(C=CC(=C3)C(=O)OCC(=O)N)Cl. InChI: InChI=1S/C22H18Cl2N2O5S/c23-17-7-9-18(10-8-17)26(13-15-4-2-1-3-5-15)32(29,30)20-12-16(6-11-19(20)24)22(28)31-14-21(25)27/h1-12H,13-14H2,(H2,25,27). |  |
| PF-3450074 | PF-3450074 (PF-74) is a specifical inhibitor of HIV-1 capsid protein (CA) and displays a broad-spectrum inhibition of HIV isolates with submicromolar potency (EC50=8-640 nM). PF-3450074 (PF-74) acts at an early stage of HIV-1 infection, inhibits viral replication by directly competing with the binding of CPSF6 and NUP153, and blocks the uncoating, assembly, and the reverse transcription steps of the viral life cycle[1][2]. CPSF6: nuclear host factors cleavage and polyadenylation specific factor 6; NUP153: nucleoporin 153. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-74. CAS No. 1352879-65-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120072. |  |
| PF-3644022 | PF-3644022 is a potent, selective, orally active and ATP-competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively. PF-3644022 potently inhibits TNFα production and has anti-inflammatory effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1276121-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107427. | |
| PF-3758309 | PF-3758309 (PF-03758309) is a potent, orally available, and reversible ATP-competitive inhibitor of PAK4 (Kd= 2.7 nM; Ki=18.7 nM). PF-3758309 has the expected cellular functions of a PAK4 inhibitor: inhibition of anchorage-independent growth, induction of apoptosis, cytoskeletal remodeling, and inhibition of proliferation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-03758309. CAS No. 898044-15-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13007. | |
| PF-3845 | PF-3845 is a potent, selective, irreversible and orally active inhibitor of fatty acid amide hydrolase (FAAH), with a Ki of 0.23 μM. PF-3845 is a covalent inhibitor that carbamylates FAAH's serine nucleophile. PF-3845 can reduce pain sensation, inflammation, and anxiety/depression without substantial effects on motility or cognition[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1196109-52-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14380. | |
| PF-4136309 | PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCB8761. CAS No. 1341224-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13245. | |
| PF-4191834 | PF-4191834 (PF-04191834) is an orally active, noniron chelating, and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) (IC50=229 nM), displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes, and is effective in inflammation and pain[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-04191834. CAS No. 1029317-21-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117048. | |
| PF-429242 | PF429242 is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 947303-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-13447. | |
| PF429242 dihydrochloride | PF429242 dihydrochloride is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2248666-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13447A. | |
| PF-431396 | PF-431396 is an orally active dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor, with IC50 values of 2 nM and 11 nM, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 717906-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10460. | |
| PF-4618433 | PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. PF-4618433 may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects and for targeted bone regeneration[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1166393-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18312. | |
| PF-4708671 | PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases. Group: Biochemicals. Alternative Names: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671. Grades: Highly Purified. CAS No. 1255517-76-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-4708671 | PF-4708671 is a potent cell-permeable S6K1 inhibitor with a Ki of 20 nM and IC50 of 160 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1255517-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15773. | |
| PF 477736 | PF 477736 (PF 00477736) is a potent, selective and ATP-competitive inhibitor of Chk1, with a Ki of 0.49 nM, it is also a Chk2 inhibitor, with a Ki of 47 nM. PF 477736 shows <100-fold selectivity for Chk1 over VEGFR2, Fms, Yes, Aurora-A, FGFR3, Flt3, and Ret (IC50=8 (Ki), 10, 14, 23, 23, 25, and 39 nM, respectively). PF 477736 can enhance Gemcitabine antitumor activity in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF 00477736. CAS No. 952021-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10032. | |
| PF-4800567 | PF-4800567 is a potent and selective inhibitor of casein kinase 1? (CK1?), with an IC50 of 32 nM, which is greater than 20-fold selectivity over CK1δ (IC50, 711 nM). Uses: Scientific research. Category: Signaling pathways. CAS No. 1188296-52-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12470. | |
| PF-4800567 Hydrochloride | PF 4800567 is a selective casein kinase 1ε inhibitor; displays 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively). ATP competitive. Displays minimal effect on the circadian clock. Group: Biochemicals. Alternative Names: 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Hydrochloride; PF 4800567 Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-4878691 | PF-4878691 (3M-852A) is an orally active TLR7 agonist. PF-4878691 has the innate immune response activity, antiviral efficacy against HCV, and can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3M-852A. CAS No. 532959-63-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100176. | |
| PF-5006739 | PF-5006739 is a potent and selective inhibitor of CK1δ/ε with IC50s of 3.9 nM and 17.0 nM, respectively. PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 attenuats opioid agent-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner[1]. PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1293395-67-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12443. | |
| PF-5081090 | PF-5081090 (LpxC-4) is a potent LpxC inhibitor, is a rapidly bactericidal with broad-spectrum activity. PF-5081090 serves as a regulator of lipid A biosynthesis in Gram-negative pathogens[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LpxC-4. CAS No. 1312473-63-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103251. | |
| PF 514273 | PF 514273. Group: Biochemicals. Grades: Purified. CAS No. 851728-60-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-514273 | A novel, bicyclic lactam-based cannabinoid-1 receptor antagonist for the treatment of obesity. Group: Biochemicals. Alternative Names: 2-(2-Chlorophenyl)-3-(4-chlorophenyl)-7-(2,2-difluoropropyl)-6,7-dihydro-2H-pyrazolo[3,4-f][1,4]oxazepin-8(5H)-one. Grades: Highly Purified. CAS No. 851728-60-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-5190457 | PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-05190457. CAS No. 1334782-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12584. | |
| PF-5274857 | PF-5274857 is a potent, selective, orally active and brain-penetrant antagonist of Smo, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1373615-35-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13459. | |
| PF-543 | PF-543 (Sphingosine Kinase 1 Inhibitor II) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 is >100-fold selectivity for SPHK1 over SPHK2. PF-543 is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 induces apoptosis, necrosis, and autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sphingosine Kinase 1 Inhibitor II. CAS No. 1415562-82-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15425. | |
| PF-543 Citrate | PF-543 Citrate (Sphingosine Kinase 1 Inhibitor II Citrate) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 Citrate is >100-fold selectivity for SPHK1 over SPHK2. PF-543 Citrate is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 Citrate induces apoptosis, necrosis, and autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sphingosine Kinase 1 Inhibitor II Citrate. CAS No. 1415562-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15425A. | |
| PF-562271 | PF-562271 (VS-6062) is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VS-6062. CAS No. 717907-75-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10459. | |
| PF-562271 | Potent ATP-competitive reversible inhibitor of FAK and Pyk2. PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC(50) of 1.5 and 14nm, respectively. In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measuring phospho-FAK with an IC(50) of 5nm. PF-562,271 was evaluated against multiple kinases and displays >100X selectivity against a long list of non target kinases. In tests, PF-562,271 inhibits FAK phosphorylation in vivo in a dose-dependent fashion with a calculated EC50 of 93ng/ml using injections. Group: Biochemicals. Grades: Highly Purified. CAS No. 717907-75-0. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C21H20F3N7O3S, Target: FGFR. US Biological Life Sciences. | Worldwide |
| PF-562271 hydrochloride | PF-562271 (VS-6062) hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VS-6062hydrochloride. CAS No. 939791-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-20403. | |
| PF-573228 | A novel focal adhesion kinase inhibitor that has been shown to suppress the adverse phenotype of endocrine-resistant breast cancer cells and improve endocrine response in endocrine-sensitive cells. Group: Biochemicals. Alternative Names: 3, 4-Dihydro-6-[[4-[[[3- (methylsulfonyl) phenyl]methyl]amino]-5- (trifluoromethyl) -2-pyrimidinyl]amino]-2 (1H) -quinolinone; 6- [ (4- ( (3- (Methanesulfonyl) benzyl) amino) -5-trifluoro methyl pyrimidin-2-yl) amino] -3, 4-dihydro-1H-quinolin-2-one; PF 573228. Grades: Highly Purified. CAS No. 869288-64-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF-573228 | PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for purified recombinant catalytic fragment of FAK. Uses: Scientific research. Category: Signaling pathways. CAS No. 869288-64-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10461. | |
| PF-573228 | PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis. Group: Inhibitors. CAS No. 869288-64-2. Pack Sizes: 10mg. Product ID: S2013. Formula: C22H20F3N5O3S. Smiles: CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| PF-573228 | PF-573228 Inhibitor. Uses: Scientific use. Product Category: T2001. CAS No. 869288-64-2. |  |
| PF 670462 | PF 670462. Group: Biochemicals. Grades: Purified. CAS No. 950912-80-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-670462 dihydrochloride | PF-670462 dihydrochloride is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50s of 7.7 nM and 14 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 950912-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15490. | |
| PF-739 | PF-739 is an orally active and non-selective activator of AMPK. PF-739 activates 12 heterotrimeric AMPK complexes and significantly reduces the level of glucose in plasma complexes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1852452-14-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117755. | |
| PF 750 | Fatty acid amide hydrolase (FAAH) inhibitor, selectively inhibiting FAAH within the central nervous system. Group: Biochemicals. Alternative Names: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide; N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide. Grades: Highly Purified. CAS No. 959151-50-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PF 8380 | PF 8380. Group: Biochemicals. Grades: Purified. CAS No. 1144035-53-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-8380 | PF-8380 is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. Uses: Scientific research. Category: Signaling pathways. CAS No. 1144035-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13344. | |
| PF-8380 hydrochloride | PF-8380 hydrochloride is a potent autotaxin inhibitor with an IC50 of 2.8 nM in isolated enzyme assay and 101 nM in human whole blood. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070015-01-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13344A. | |
| PF 915275 | PF 915275. Group: Biochemicals. Grades: Purified. CAS No. 857290-04-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PF-915275 | PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 857290-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18056. | |
| PF-9363 | PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CTx-648. CAS No. 2569009-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132283. | |
| PF-9366 | PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 72882-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107778. | |
| PF9 tetrasodium salt | PF9 tetrasodium salt. Group: Biochemicals. Grades: Purified. CAS No. 851265-78-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PFB-FDGlu | PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 209540-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139452. | |
| PFB-mercaptopropionyl-TOTA-Biotinyl | PFB-mercaptopropionyl-TOTA-Biotinyl. |  |
| PFD | PFD. Alternative Names: Poly(9,9-di-n-dodecylfluorene). CAS No. 248256-53-3. | |
| PfDHODH-IN-1 | PfDHODH-IN-1, an analogue of the active Leflunomide metabolite, exhibits antimalarial activity. Category: Active pharmaceutical ingredients. CAS No. 183945-55-3. Product ID: API183945553. Molecular formula: C14H11F3N2O2. Mole weight: 296.24. |  |
| PF-DMB | PF-DMB. Alternative Names: PF-DMB;Poly[(9,9-dihexylfluoren-2,7-diyl)-alt-(2,5-dimethyl-1,4-phenylene)]. CAS No. 579505-48-9. Purity: 96%. | |
| PFE-360 | PFE-360 Inhibitor. Uses: Scientific use. Product Category: T16512. CAS No. 1527475-61-1. | |
| PFE-360 | PFE-360 (PF-06685360) is a potent, selective, brain penetrated and orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor with a mean IC50 of 2.3 nM in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06685360. CAS No. 1527475-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120085. | |
| PffBT4T-2OD | Band gap: 1.65 eV. Alternative Names: PCE-11,Poly[(5,6-difluoro-2,1,3-benzothiadiazol-4,7-diyl)-alt-(3,3'''-di(2-octyldodecyl)-2,2',5',2'',5'',2'''-quaterthiophen-5,5'''-diyl)]. CAS No. 1644164-62-4. Molecular formula: (C62H88F2N2S5)n. | |
| PffBT4T-C9C13 | PffBT4T-C9C13. | |
| PFI-1 | PFI-1, a chemical probe, is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM in a cell-free assay. Uses: Scientific research. Category: Signaling pathways. CAS No. 1403764-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16586. | |
| PFI-1 | PFI-1. Group: Biochemicals. Alternative Names: 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide; 2-Methoxy-N- (1, 2, 3, 4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl) benzenesulfonamide. Grades: Highly Purified. CAS No. 1403764-72-6. Pack Sizes: 5mg. Molecular Formula: C16H17N3O4S, Molecular Weight: 347.39. US Biological Life Sciences. | Worldwide |
| PFI-2 | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride, a chemical probe, is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-PFI-2. CAS No. 1627676-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18627. | |
| PFI-2 hydrochloride | PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0??nM and (S)-PFI-2 shows inhibiting activity with IC50 ?value of?1.0??μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-PFI-2 hydrochloride. CAS No. 1627607-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18627A. | |
| PFI-2 Hydrochloride | PFI-2 Hydrochloride. Alternative Names: PFI-2; PFI2; PFI 2; (R)-PFI-2; (R)-PFI-2 hydrochloride. PFI-2 hydrochloride. CAS No. 1627607-87-7. Purity: ≥98%. Product ID: ACM1627607877. Molecular formula: C23H26ClF4N3O3S. Mole weight: 535.9826 g/mol. IUPAC Name: (R)-8-fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| PFI-3 | PFI-3, a chemical probe, is a selective, potent and cell-permeable SMARCA2/4 bromodomain inhibitor with a Kd of 89 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1819363-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12409. | |
| PFI-6 | PFI-6 is a selective MLLT1 and MLLT3 YEATS domain probe with IC50 values of 0.14 μM and 0.16 μM, respectively. PFI-6 is applicable for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2675452-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-155412. | |
| PFI-90 | PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1). Uses: Scientific research. Category: Signaling pathways. CAS No. 53995-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-139348. | |
| PFIID | PFIID. CAS No. 2019220-88-1. Molecular formula: (C85H128N2O2)n. | |
| PFK-015 | PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 4382-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12204. | |
| PFK-158 | PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1462249-75-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12203. | |
| PFKFB4-IN-1 | PFKFB4-IN-1 is a potent and selective ATP-competitive PFKFB4 inhibitor (IC50 = 4.50 μM) that reduces intracellular PFKFB4 protein levels. PFKFB4-IN-1 exhibits >12-fold selectivity over PFKFB1/4 and PFKFB3/4. PFKFB4-IN-1 inhibits cancer cell proliferation, induces apoptosis, and inhibits cell migration. PFKFB4-IN-1 inhibits tumor growth in the MDA-MB-231 xenograft mouse model. PFKFB4-IN-1 can be used for breast, lung and liver cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2664831-55-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-178367. | |
| p-Fluoropropiophenone | p-Fluoropropiophenone. Group: Biochemicals. Grades: Highly Purified. CAS No. 456-03-1. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| p-Fluorostyrene | p-Fluorostyrene. Alternative Names: 4-Fluorostyrene, 97%, stabilized; AS03795; ST2403438; RTR-033260; 4-Fluorostyrene, 99%; AN-44804; 405-99-2; ACN-S004611; CTK3J0456; I01-7785. CAS No. 405-99-2. Molecular formula: C8H7F. Mole weight: 122.142g/mol. IUPAC Name: 1-ethenyl-4-fluorobenzene. SMILES: C=CC1=CC=C(C=C1)F. InChI: InChI=1S/C8H7F/c1-2-7-3-5-8(9)6-4-7/h2-6H,1H2. | |
| PFM01 | PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1558598-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-116770. | |
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