A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PI230 is an antimicrobial peptide found in Pisum sativum (Garden pea), and has antimicrobial activity. Synonyms: Defensin-like protein 230. Grade: >98%.
PI-273
PI-273 is a first reversibly and specific phosphatidylinositol 4-kinase (PI4KII?) inhibitor with an IC50 of 0.47 ?M. PI-273 can inhibit breast cancer cell proliferation, block the cell cycle and induce cell apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925069-34-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103489.
The PI 3,4-K inhibitor, PIK-93, also referenced under CAS 593960-11-3, controls the biological activity of PI 3,4-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable phenylthiazole compound that acts as a potent, reversible and ATP-competitive PI 3,4-K family selective inhibitor (IC50=16, 19, 39 and 64nM for p110y, PI 4-KIIb, p110a and DNA-PK, respectively). Moderately inhibits p110d, PI 3-KC2b, hsVPS34, ATM, p110b and PI 4-KIIIa (IC50=0.120, 0.140, 0.320, 0.490, 0.590 and 1.1uM, respectively) with minimal inhibition towards a panel of 36-kinases (IC50>10uM). Shown to block ceramide transfer protein-mediated ceramide traffic between endoplasmic reticulum and Golgi in transfected COS-7 cells at 250nM. Group: Biochemicals. Grades: Highly Purified. CAS No. 593960-11-3. Pack Sizes: 5mg. US Biological Life Sciences.
PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2684412-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147768.
PI3K-AKT-mTOR Compound Library
A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; - Effective tool for studying cell growth, proliferation, and apoptosis; - Targets include AKT, AMPK, mTOR, PI3K, ATR/ATM, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1300. Categories: PI3K-AKT-mTOR Compounds Libraries.
PI3Kδ/γ-IN-1
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1980884-01-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144993.
PI3Kδ-IN-16
PI3Kδ-IN-16 is a potent and selective inhibitor of PI3K&delta. PI3Kδ-IN-16 has a strong anti-proliferative effect on cells, causing cell cycle arrest and inducing apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766437-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155232.
PI3K-IN-32
PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC 50 of 6.85 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371934-59-7. Pack Sizes: 5 mg. Product ID: HY-103030.
PI3K-IN-46
PI3K-IN-46 (Intermediate 4) is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304645-61-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-48869.
The PI 3-K? Inhibitor, also referenced under CAS 648450-29-7, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor II - CAS 648449-76-7
The PI 3-K? Inhibitor II, also referenced under CAS 648449-76-7, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor IV - CAS 1188890-32-5
The PI 3-K? Inhibitor IV, also referenced under CAS 1188890-32-5, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K inhibitor IX, PIK-90 - CAS 677338-12-4
The PI 3-K inhibitor IX, PIK-90, also referenced under CAS 677338-12-4, controls the biological activity of PI 3-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI3K? Inhibitor, SW30
The PI3K? Inhibitor, SW30 controls the biological activity of PI3K?. This small molecule/inhibitor is primarily used for Membrane applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VII - CAS 6318-41-8
The PI 3-K? Inhibitor VII, also referenced under CAS 6318-41-8, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VIII - CAS 372196-77-5
The PI 3-K? Inhibitor VIII controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor VI, TGX-221 - CAS 663619-89-4
The PI 3-K? Inhibitor VI, TGX-221, also referenced under CAS 663619-89-4, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K? Inhibitor X, IC87114 - CAS 371242-69-2
The PI 3-K? Inhibitor X, IC87114, also referenced under CAS 371242-69-2, controls the biological activity of PI 3-K?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K Inhibitor XI, HWT - CAS 58053-83-1
The PI 3-K Inhibitor XI, HWT, also referenced under CAS 58053-83-1, controls the biological activity of PI 3-K. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K Inhibitor XVIII (p110 beta-G beta gamma Interaction Inhibitor peptide, Cell-permeable, Myr-N-KAAEIASSDSANVSSRGGKKFL PV-NH2)
An N-myristoylated cell-permeable PI 3-K p110 beta-derived G beta-gamma-binding peptide (aa514-537 in p110 beta C2-helical linker region) that prevents G beta-gamma-, but not RTK-, mediated p100 beta activation both in cell-free assays (1uM) and in cultures (30uM in p110 beta/p85/Akt/G beta-gamma-transfected HEK 293E cells) without affecting basal p100 beta activity, p110 beta-Rab5 interaction, nor G beta-gamma-dependent activation of adenylyl cyclase or p101-p110-gamma dimer. The ATP-competitive p110 beta inhibitior TGX-221 can be used in conjunction for studying G beta-gamma dependency of p110 beta-mediated cellular functions. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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PI 3-K?/? Inhibitor XV, SW-14
The PI 3-K?/? Inhibitor XV, SW-14 controls the biological activity of PI 3-K?/?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K/mTOR Inhibitor III, PKI-179 - CAS 1197160-28-3
The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI 3-K/PDK-1 Inhibitor, NVP-BAG956 - CAS 853910-02-8
The PI 3-K/PDK-1 Inhibitor, NVP-BAG956, also referenced under CAS 853910-02-8, controls the biological activity of PI 3-K/PDK-1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
PI5P4Kα-IN-1 (Compound 13) is a PI5P4K inhibitor ( IC 50 : 2 and 9.4 μM for PI5P4Kα and PI5P4Kβ). PI5P4Kα-IN-1 can be used for research of cancer, metabolic and immunological disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2428737-31-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153531.
PI5P4Kγ-IN-1
PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419358-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153789.
PI 828
PI 828. Group: Biochemicals. Grades: Purified. CAS No. 942289-87-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
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PIAnCN
PIAnCN. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-(10-(4-(1-Phenyl-1H-phenanthro[9,10-d]imidazol-2-yl)phenyl) anthracen-9-yl)benzonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2186679-41-2. Molecular formula: C48H29N3. Mole weight: 647.76 g/mol. Product ID: ACM2186679412. Alfa Chemistry ISO 9001:2015 Certified. Categories: Piano.
PIANO n-Paraffins Mixture 99
PIANO n-Paraffins Mixture 99. Uses: For analytical and research use. Group: Hydrocarbons & petrochemicals. Catalog: APS011260. Format: Mixture. Shipping: Room Temperature.
PiB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IN1141; diethyl 1,3,6,8-tetrahydro-1,3,6,8-tetraoxobenzo[lmn][3,8]phenanthroline-2,7-diacetate; phenanthroline-(2H,7H)-diacetate; (1,3,6,8-Tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthrolin-2,7-diyl)-di-essigsaeure-diaethylester; (1,3,6,8-tetraoxo-1. Product Category: Heterocyclic Organic Compound. CAS No. 64005-90-9. Molecular formula: C22H18N2O8. Mole weight: 438.39. Purity: 0.96. IUPACName: PPIase-Parvulin Inhibitor. Canonical SMILES: CCOC(=O)CN1C(=O)C2=C3C(=CC=C4C3=C(C=C2)C(=O)N(C4=O)CC(=O)OCC)C1=O. Density: 1.471g/cm³. Product ID: ACM64005909. Alfa Chemistry ISO 9001:2015 Certified.
Piboserod
Piboserod (SB 207266) is a 5-HT4 selective inhibitor of the serotonin receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-207266. CAS No. 152811-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15574.
Pibrentasvir
Pibrentasvir is a novel and pan-genotypic hepatitis C virus ( HCV ) NS5A inhibitor with EC 50 s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-530. CAS No. 1353900-92-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101662.
Picamilon
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid. CAS No. 34562-97-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-107482.
Picankibart
Picankibart is a mouse-derived IgG1κ antibody targeting IL23A [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2622900-74-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990057.
Picaridin
Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Insect repellent. Picaridin is an insect repellent that is effective against a range of arthropods, including mosquitoes and ticks.1,2 It shows synergy with the non-pyrethroid insecticide propoxur both in killing and repelling mosquitoes.3 Picaridin and other insect repellents have been shown to act as either agonists or antagonists at insect olfactory receptors.4,5. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-propyl Ester; Icaridin; KBR 3023; Bayrepel. Grades: Highly Purified. CAS No. 119515-38-7. Pack Sizes: 100g, 250g, 500g. US Biological Life Sciences.
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Picaridin
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. The repellent and deterrent activities of Picaridin involve olfactory sensing in mosquitoes, and ticks, via their interactions with odorant receptor proteins. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Liquid. CAS No. 119515-38-7. Molecular formula: C12H23NO3. Mole weight: 229.32. Purity: ≥93%. Canonical SMILES: O=C(N1C(CCCC1)CCO)OC(CC)C. Product ID: ACM119515387-3. Alfa Chemistry ISO 9001:2015 Certified.
Picaridin
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial , anticandidal and antifungal properties [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lcaridin. CAS No. 119515-38-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-116144.
Picaridin-d3
Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-piperidinecarboxylic Acid 1-Methyl-d3-propyl Ester; Icaridin-d3; KBR 3023-d3; Bayrepel-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Piceain 1
Piceain 1 is an antimicrobial peptide found in Picea sitchensis, and has activity against E.coli, P.aerμginosa, S.aureus and fungus C.albicans. It shows weak hemolysis activity. Synonyms: H-Lys-Ser-Leu-Arg-Pro-Arg-Cys-Trp-Ile-Lys-Ile-Lys-Phe-Arg-Cys-Lys-Ser-Leu-Lys-Phe-OH; L-lysyl-L-seryl-L-leucyl-L-arginyl-L-prolyl-L-arginyl-L-cysteinyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-lysyl-L-phenylalanyl-L-arginyl-L-cysteinyl-L-lysyl-L-seryl-L-leucyl-L-lysyl-L-phenylalanine. Grade: ≥96%. Molecular formula: C118H197N35O23S2. Mole weight: 2538.18.
Piceain 2
Piceain 2 is an antimicrobial peptide found in Picea sitchensis, and has activity against E.coli, P.aeruginosa, S.aureus and fungus C.albicans. It shows weak hemolysis activity. Synonyms: H-Arg-Pro-Arg-Cys-Trp-Ile-Lys-Ile-Lys-Phe-Arg-Cys-Lys-Ser-Leu-Lys-Phe-OH; L-arginyl-L-prolyl-L-arginyl-L-cysteinyl-L-tryptophyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-lysyl-L-phenylalanyl-L-arginyl-L-cysteinyl-L-lysyl-L-seryl-L-leucyl-L-lysyl-L-phenylalanine. Grade: ≥95%. Molecular formula: C103H169N31O19S2. Mole weight: 2209.77.
Piceatannol
Piceatannol, a natural stilbene, is a selective Syk inhibitor and ~10-fold selectivity versus Lyn. Uses: Antioxidant, and anti-inflammatory activities; antitumor activity. Synonyms: Piceatannol; NSC 622471; NSC-622471; NSC622471. Grade: >98%. CAS No. 10083-24-6. Molecular formula: C14H12O4. Mole weight: 244.24.
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) [1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties [2]. Piceatannol induces apoptosis in DLBCL cell lines [3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Astringenin; trans-Piceatannol. CAS No. 10083-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13518.
Piceatannol
Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB activation through IkBalpha kinase inhibition. Activator of human deacetylase SIRT1 (sirtuin 1). Potent antioxidant with anti-proliferative, anti-inflammatory and cardioprotective properties. Neuoprotective. Adipogenesis inhibitor. Promotes glucose uptake, AMPK phosphorylation and GLUT4 translocation. Group: Biochemicals. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H??O?. US Biological Life Sciences.
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Piceatannol 3'-O-glucoside
Piceatannol 3'-O-glucoside. Group: Biochemicals. CAS No. 94356-26-0. Pack Sizes: 5mg. US Biological Life Sciences.
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Piceatannol, (E)-
Piceatannol, (E)-. Group: Biochemicals. CAS No. 10083-24-6. Pack Sizes: 5mg. US Biological Life Sciences.
A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M)1. Stimulates Sirt12. Group: Biochemicals. Alternative Names: SIRT1 Activator,3,3?,4,5?-Tetrahydroxy-transstilbene. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
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Piceatannol (trans-Picetannol, Astringenin)
Cell-permeable. Kartogenin promotes the differentiation of multipotent mesenchymal stem cells into chondrocytes (EC50 = 100nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis. Group: Biochemicals. Alternative Names: trans-3,3',4,5'-Tetrahydroxystilbene. Grades: Highly Purified. CAS No. 10083-24-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
Picein
Picein, isolated from Picrorhiza kurroa , is a naturally occurring antioxidant [1]. Uses: Scientific research. Group: Natural products. CAS No. 530-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8698.