A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα and IL-4Rα inhibitor with a KD of 20.7 pM when binding to human IL-4Rα epitopes. Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and thymus activation regulated chemokine (TRAC) production. Rademikibart can be used for the research of atopic dermatitis and asthma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBP-201. CAS No. 2648260-80-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990090.
Radezolid
Radezolid (RX-1741) is a novel oxazolidinone antibiotic. Category: Active pharmaceutical ingredients. CAS No. 869884-78-6. Product ID: API869884786. Molecular formula: C22H23FN6O3. Mole weight: 438.45.
Radicicol
Antibiotic. Protein tyrosine kinase inhibitor. Has antifungal, antimalarial, antiangiogenic (in vivo), anti-inflammatory and antiviral activity. Cyclooxygenase-2 (COX-2) expression inhibitor without affecting COX-1 expression in LPS-stimulated macrophages. Induces the differentiation of HL-60 cells into macrophages. Potent HSP90 inhibitor. Anticancer compound. In vivo Rad/Raf interaction inhibitor. Inhibitor of AP-1-, NF-kappaB- and serum response factor (SRF)-mediated transcription. Suppresses expression of iNOS (NOS II). Non-competitive inhibitor of ATP citrate lyase. DNA topoisomerase VI and type II DNA topoisomerase inhibitor. Protects against LPS/IFN-gamma-induced neuronal cell death. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C18H17ClO6. US Biological Life Sciences.
Worldwide
Radicicol
Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation[1]. Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB[2]. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monorden. CAS No. 12772-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6769.
Radicicol (Monorden)
Radicicol is a resorcylic acid lactone produced by several fungal species that exhibits broad spectrum antifungal and antitumor activity. Radicicol has been the subject of extensive investigation and been shown to inhibit protein tyrosine kinase, induce the differentiation of HL-60 cells into macrophages, block cell cycle at G1 and G2, suppress NIH 3T3 cell transformation by diverse oncogenes such as src, ras and mos and also suppress the expression of mitogen-inducible cyclooxygenase-2. As a cell differentiation modulator, radicicol has anti-angiogenic activity in vivo, inhibiting the proliferation of plasminogen activator production by vascular endothelial cells. Group: Biochemicals. Alternative Names: Monorden. Grades: Highly Purified. CAS No. 12772-57-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Radicinin
Radicinin is produced by the strain of Curvularia lunata IAM-18010. It has anti-bacterial effect, but its activity is weak. Alternative Names: Stemphylone; NSC 118343; 2,3-Dihydro-3-alpha-hydroxy-2-beta-methyl-7-propenyl-4H,5H-pyrano(4,3-b)pyran-4,5-dione. CAS No. 10088-95-6. Molecular formula: C12H12O5. Mole weight: 236.22.
Radioprotectin-1
Radioprotectin-1 is a potent and specific nonlipid agonist of lysophosphatidic acid receptor 2 (LPA2), with an EC50 value of 25 nM for murine LPA2 subtype[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1622006-09-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114380.
Radiprodil
Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGH-896. CAS No. 496054-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14777.
Radiprodil
Radiprodil is an orally active and selective NMDA NR2B antagonist as a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions, blocking pain signaling without interacting with other NMDA receptor subtypes thus potentially improving therapeutic index and side effect profile. Uses: Nmda nr2b antagonist. Alternative Names: RGH-896; RGH896; RGH 896; 2-(4-((4-Fluorophenyl)methyl)piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide. Grades: ≥98%. CAS No. 496054-87-6. Molecular formula: C21H20FN3O4. Mole weight: 397.41.
Radix isatidis Extract (Standard)
Radix isatidis Extract (Standard). Applications: Lowering blood pressure, weight loss, prevention and treatment of atherosclerosis and thrombosis and other cardiovascular disease, lowering blood sugar, diabetes control, sterilization; control hepatitis, fatty liver, anti-aging and immune function; cancer , anti-allergy, colds, prevent fractures. Group: Others. Synonyms: Radix isatidis Extract (Standard). Purity: 5:1, 10:1,10%, TLC/HPLC. Appearance: Purple needle crystal. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Isatis tinctoria L. and Isatis indigotica Fort. Radix isatidis Extract (Standard); plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-199.
Radix Notoginseng Extract
Radix Notoginseng Extract. Applications: Used for health care products, dietary supplements, anti-inflammatory, anti-fatigue, anti-cancer. Group: Others. Synonyms: Radix Notoginseng Extract; Panax notoginseng(Burk.) F.H.Chen. Purity: 10:1, 20:1 By TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Panax notoginseng(Burk.) F.H.Chen. Radix Notoginseng Extract; Panax notoginseng(Burk.) F.H.Chen; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-112.
Radix Ophiopogonis Extract
Radix Ophiopogonis Extract. Applications: Used for health care products, dietary supplements, herb medecine for heart health. Group: Others. Synonyms: Radix Ophiopogonis Extract; Ophiopogon japonicus(Thunb.). Purity: 5:1 by TLC. Appearance: Brown-yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Ophiopogon japonicus(Thunb.). Radix Ophiopogonis Extract; Ophiopogon japonicus(Thunb.); plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-142.
Radix polygoni multiflori extract
Radix polygoni multiflori extract is prepared from the tuber of prepared Radix Polygoni Multiflori plant (radix polygoni multiflori preparata) that oringinated in China, which latin name is Radix Polygoni Multiflori. Radix polygoni multiflori extract (also known as He shou wu extract, fo ti extract) is a ancient China medical herb that have been used for thousand years, it's commonly used for anti-aging, enhance immunity, hypolipidemic, and anti-atherosclerosis. Group: Others. Radix polygoni multiflori extract; Radix Polygoni Multiflori. Cat No: EXTC-001.
Radix Rehmanniae Extract
Radix Rehmanniae Extract. Applications: Used for women health care products, dietary supplements. Group: Others. Synonyms: Radix Rehmanniae Extract; Rehmannia glutinousa Libosch. Purity: 10:1 By TLC. Appearance: Deep brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Rehmannia glutinousa Libosch. Radix Rehmanniae Extract; Rehmannia glutinousa Libosch.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-095.
Radix Rehmanniae Preparata Extract
Radix Rehmanniae Preparata Extract. Applications: Used for men health care products, dietary supplements, drink additive, for deficiency of liver and kidney. Group: Others. Synonyms: Radix Rehmanniae Preparata Extract; Radix Rehmanniae Preparata. Purity: 5-10:1 by TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Radix Rehmanniae Preparata. Radix Rehmanniae Preparata Extract; Radix Rehmanniae Preparata; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-083.
Radix Saposhnikovia Extract
Radix Saposhnikovia Extract. Applications: Used for women health care products, dietary supplements, treat rheumatism, arthralgia. Group: Others. Synonyms: Radix Saposhnikovia Extract; Saposhnikovia divaricata (Turcz.) Schischk. Purity: 10:1 By TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Saposhnikovia divaricata (Turcz.) Schischk. Radix Saposhnikovia Extract; Saposhnikovia divaricata (Turcz.) Schischk.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-093.
Radotinib
Radotinib (IY-5511) is an orally active and BBB-permeable selective tyrosine kinase Bcr-Abl1 inhibitor with an IC50 of 34 nM. Radotinib has anti-prion and anti-tumor activities. Radotinib can inhibit the proliferation, induce cell cycle arrest and apoptosis of tumor cells. Radotinib can be used in the research of cancer such as chronic myeloid leukemia and multiple myeloma, as well as neurodegenerative diseases such as prion diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IY-5511. CAS No. 926037-48-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15728.
Radotinib
Radotinib, also known as IY-5511, is an orally available, hydrochloride salt form of radotinib, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. The inhibitory effect of radotinib on these specific tyrosine kinases may decrease cellular proliferation and inhibit angiogenesis. This agent has shown potent efficacy in CML cells that are resistant to the first-generation standard tyrosine kinase inhibitors, such as imatinib, nilotinib and dasatinib. PDGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: IY-5511; IY 5511; IY5511; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyrazin-2-ylpyrimidin-2-yl)amino]benzamide. Grades: >98%. CAS No. 926037-48-1. Molecular formula: C27H21F3N8O. Mole weight: 530.515.
Radotinib-[d6]
Radotinib-[d6] is deuterium labelled Radotinib. Radotinib, also known as IY-5511, is a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Alternative Names: 4-(Methyl-d3)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide-2,5,6-d3. CAS No. 2754051-83-5. Molecular formula: C27H15D6F3N8O. Mole weight: 536.55.
RadotinibI
Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other tyrosine kinase Bcr-Abl inhibitors. Category: Active pharmaceutical ingredients. CAS No. 926037-48-1. Product ID: API926037481. Molecular formula: C27H21F3N8O. Mole weight: 530.5.
RAF265
RAF265 is a potent and orally active RAF/VEGFR2 inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHIR-265. CAS No. 927880-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10248.
RAF709
RAF709 is a potent, selective, and efficacious RAF inhibitor with IC50s of 0.4 nM and 0.5 nM for BRAF and CRAF, respectively[1]. Antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628838-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100510.
RAF-709
RAF-709 is a novel Raf kinase inhibitor used for the treatment of non-small cell lung cancer (NSCLC). Uses: The treatment of nsclc. Alternative Names: N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; RAF709; RAF-709; RAF 709. Grades: 98%. CAS No. 1628838-42-5. Molecular formula: C28H29F3N4O4. Mole weight: 542.56.
Raffenacin impurity 42 (zopiclone impurity 7) (piperidine-4-carboxamide). Uses: For analytical and research use. CAS No. 39546-32-2. Molecular formula: C6H12N2O. Mole weight: 128.18. Catalog: APB39546322.
Raffinazine impurity 1
Raffinazine impurity 1. Uses: For analytical and research use. CAS No. 3001303-50-7. Molecular formula: C35H43N5O5. Mole weight: 613.76. Catalog: APB3001303507.
Raffinazine impurity 10
Raffinazine impurity 10. Uses: For analytical and research use. CAS No. 743460-48-2. Molecular formula: C21H27N3O2. Mole weight: 353.47. Catalog: APB743460482.
Raffinazine impurity 11
Raffinazine impurity 11. Uses: For analytical and research use. CAS No. 1289178-26-2. Molecular formula: C19H22N2O2. Mole weight: 310.4. Catalog: APB1289178262.
Raffinazine impurity 12
Raffinazine impurity 12. Uses: For analytical and research use. CAS No. 38711-20-5. Molecular formula: C6H15NO2. Mole weight: 133.19. Catalog: APB38711205.
Raffinazine impurity 13
Raffinazine impurity 13. Uses: For analytical and research use. CAS No. 14882-18-9. Molecular formula: C7H5BiO4. Mole weight: 362.09. Catalog: APB14882189.
Raffinazine impurity 14
Raffinazine impurity 14. Uses: For analytical and research use. CAS No. 1682660-39-4. Molecular formula: C29H33N3O4. Mole weight: 487.6. Catalog: APB1682660394.
Raffinazine impurity 15
Raffinazine impurity 15. Uses: For analytical and research use. CAS No. 864760-28-1. Molecular formula: C29H31N3O4. Mole weight: 485.58. Catalog: APB864760281.
Raffinazine impurity 16
Raffinazine impurity 16. Uses: For analytical and research use. CAS No. 909899-69-0. Molecular formula: C31H37N5O4. Mole weight: 543.67. Catalog: APB909899690.
Raffinazine impurity 17
Raffinazine impurity 17. Uses: For analytical and research use. CAS No. 886508-20-9. Molecular formula: C12H21N3O2. Mole weight: 239.32. Catalog: APB886508209.
Raffinazine impurity 18
Raffinazine impurity 18. Uses: For analytical and research use. CAS No. 864751-39-3. Molecular formula: C29H29Br2N3O5. Mole weight: 659.38. Catalog: APB864751393.
Raffinazine impurity 19
Raffinazine impurity 19. Uses: For analytical and research use. Molecular formula: C22H34N4O3. Mole weight: 402.54. Catalog: APB11329.
Raffinazine impurity 2
Raffinazine impurity 2. Uses: For analytical and research use. CAS No. 3001303-52-9. Molecular formula: C35H43N5O5. Mole weight: 613.76. Catalog: APB3001303529.
Raffinazine impurity 20
Raffinazine impurity 20. Uses: For analytical and research use. CAS No. 643-58-3. Molecular formula: C13H12. Mole weight: 168.24. Catalog: APB643583.
Raffinazine impurity 21
Raffinazine impurity 21. Uses: For analytical and research use. Molecular formula: C50H56N6O6. Mole weight: 837.03. Catalog: APB11330.
Raffinazine impurity 23
Raffinazine impurity 23. Uses: For analytical and research use. Molecular formula: C29H33N3O3. Mole weight: 471.6. Catalog: APB11331.
Raffinazine impurity 24
Raffinazine impurity 24. Uses: For analytical and research use. CAS No. 938143-02-3. Molecular formula: C14H18N2O3. Mole weight: 262.31. Catalog: APB938143023.
Raffinazine impurity 25
Raffinazine impurity 25. Uses: For analytical and research use. CAS No. 1158699-78-5. Molecular formula: C14H17NO4. Mole weight: 263.29. Catalog: APB1158699785.
Raffinazine impurity 26
Raffinazine impurity 26. Uses: For analytical and research use. Molecular formula: C36H46N4O3. Mole weight: 582.79. Catalog: APB11332.
Raffinazine impurity 27
Raffinazine impurity 27. Uses: For analytical and research use. Molecular formula: C22H33N3O4. Mole weight: 403.52. Catalog: APB11334.
Raffinazine impurity 28
Raffinazine impurity 28. Uses: For analytical and research use. Molecular formula: C18H20N2O2. Mole weight: 296.37. Catalog: APB11333.
Raffinazine impurity 29
Raffinazine impurity 29. Uses: For analytical and research use. CAS No. 63057-17-0. Molecular formula: C11H15NO2. Mole weight: 193.25. Catalog: APB63057170.
Raffinazine impurity 3
Raffinazine impurity 3. Uses: For analytical and research use. CAS No. 50443-60-2. Molecular formula: C13H11NO2. Mole weight: 213.24. Catalog: APB50443602.
Raffinazine impurity 30
Raffinazine impurity 30. Uses: For analytical and research use. Molecular formula: C11H13Cl2NO2. Mole weight: 262.13. Catalog: APB11335.
Raffinazine impurity 31
Raffinazine impurity 31. Uses: For analytical and research use. Molecular formula: C19H19Cl2NO3. Mole weight: 380.27. Catalog: APB11336.
Raffinazine impurity 32
Raffinazine impurity 32. Uses: For analytical and research use. Molecular formula: C14H22N2O3. Mole weight: 266.34. Catalog: APB11338.
Raffinazine impurity 33
Raffinazine impurity 33. Uses: For analytical and research use. Molecular formula: C11H15NO3. Mole weight: 209.25. Catalog: APB11337.
Raffinazine impurity 34
Raffinazine impurity 34. Uses: For analytical and research use. Molecular formula: C11H14ClNO2. Mole weight: 227.69. Catalog: APB11339.
Raffinazine impurity 35
Raffinazine impurity 35. Uses: For analytical and research use. Molecular formula: C18H26N2O4. Mole weight: 334.42. Catalog: APB11341.
Raffinazine impurity 36
Raffinazine impurity 36. Uses: For analytical and research use. Molecular formula: C23H34N4O4. Mole weight: 430.55. Catalog: APB11340.
Raffinazine impurity 38
Raffinazine impurity 38. Uses: For analytical and research use. Molecular formula: C16H23N3O3. Mole weight: 305.38. Catalog: APB11342.
Raffinazine impurity 39
Raffinazine impurity 39. Uses: For analytical and research use. CAS No. 17337-13-2. Molecular formula: C13H9NO. Mole weight: 195.22. Catalog: APB17337132.
Raffinazine impurity 4
Raffinazine impurity 4. Uses: For analytical and research use. Molecular formula: C35H43N5O6. Mole weight: 629.76. Catalog: APB11328.
Raffinazine impurity 41
Raffinazine impurity 41. Uses: For analytical and research use. CAS No. 171723-80-1. Molecular formula: C25H26N2O2. Mole weight: 386.5. Catalog: APB171723801.
Raffinazine impurity 43
Raffinazine impurity 43. Uses: For analytical and research use. CAS No. 57561-39-4. Molecular formula: C8H17NO3. Mole weight: 175.23. Catalog: APB57561394.
Raffinazine impurity 44
Raffinazine impurity 44. Uses: For analytical and research use. CAS No. 6301-18-4. Molecular formula: C15H15NO2. Mole weight: 241.29. Catalog: APB6301184.
Raffinazine impurity 45
Raffinazine impurity 45. Uses: For analytical and research use. CAS No. 50663-73-5. Molecular formula: C10H14ClN. Mole weight: 183.68. Catalog: APB50663735.
Raffinazine impurity 46
Raffinazine impurity 46. Uses: For analytical and research use. Molecular formula: C38H47ClN4O2. Mole weight: 627.27. Catalog: APB11343.
Raffinazine impurity 47
Raffinazine impurity 47. Uses: For analytical and research use. Molecular formula: C38H47N4O2+. Mole weight: 591.82. Catalog: APB11344.
Raffinazine impurity 48
Raffinazine impurity 48. Uses: For analytical and research use. Molecular formula: C27H31N3O2. Mole weight: 429.56. Catalog: APB11346.
Raffinazine impurity 49
Raffinazine impurity 49. Uses: For analytical and research use. Molecular formula: C35H41N5O5. Mole weight: 611.74. Catalog: APB11345.
Raffinazine impurity 5
Raffinazine impurity 5. Uses: For analytical and research use. Molecular formula: C35H41N4NaO5. Mole weight: 620.73. Catalog: APB11327.
Raffinazine impurity 50
Raffinazine impurity 50. Uses: For analytical and research use. Molecular formula: C29H31N3O5. Mole weight: 501.58. Catalog: APB11349.
Raffinazine impurity 51
Raffinazine impurity 51. Uses: For analytical and research use. Molecular formula: C64H74N8O8. Mole weight: 1083.34. Catalog: APB11347.
Raffinazine impurity 52
Raffinazine impurity 52. Uses: For analytical and research use. Molecular formula: C35H45N5O3. Mole weight: 583.78. Catalog: APB11348.
Raffinazine impurity 6
Raffinazine impurity 6. Uses: For analytical and research use. CAS No. 909800-36-8. Molecular formula: C35H42N4O5. Mole weight: 598.74. Catalog: APB909800368.