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| Product | Description | |
|---|---|---|
| Radicinol | Radicinol is a phytotoxic fungal metabolite originally isolated from A. chrysanthemi. Synonyms: (7S,8S,9S)-7,8-Dihydroxy-9-methyl-3-((E)-prop-1-enyl)-4,10-dioxabicyclo(4.4.0)deca-2,11-dien-5-one. Grades: ≥95%. CAS No. 65647-66-7. Molecular formula: C12H14O5. Mole weight: 238.24. |  |
| Radiprodil | Radiprodil is an orally active and selective NMDA NR2B antagonist as a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions, blocking pain signaling without interacting with other NMDA receptor subtypes thus potentially improving therapeutic index and side effect profile. Uses: Nmda nr2b antagonist. Synonyms: RGH-896; RGH896; RGH 896; 2-(4-((4-Fluorophenyl)methyl)piperidin-1-yl)-2-oxo-N-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)acetamide. Grades: ≥98%. CAS No. 496054-87-6. Molecular formula: C21H20FN3O4. Mole weight: 397.41. | |
| Radiprodil | Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RGH-896. CAS No. 496054-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14777. |  |
| Radix isatidis Extract (Standard) | Radix isatidis Extract (Standard). Applications: Lowering blood pressure, weight loss, prevention and treatment of atherosclerosis and thrombosis and other cardiovascular disease, lowering blood sugar, diabetes control, sterilization; control hepatitis, fatty liver, anti-aging and immune function; cancer , anti-allergy, colds, prevent fractures. Group: Others. Synonyms: Radix isatidis Extract (Standard). Purity: 5:1, 10:1,10%, TLC/HPLC. Appearance: Purple needle crystal. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Isatis tinctoria L. and Isatis indigotica Fort. Radix isatidis Extract (Standard); plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-199. |  |
| Radix Notoginseng Extract | Radix Notoginseng Extract. Applications: Used for health care products, dietary supplements, anti-inflammatory, anti-fatigue, anti-cancer. Group: Others. Synonyms: Radix Notoginseng Extract; Panax notoginseng(Burk.) F.H.Chen. Purity: 10:1, 20:1 By TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Panax notoginseng(Burk.) F.H.Chen. Radix Notoginseng Extract; Panax notoginseng(Burk.) F.H.Chen; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-112. | |
| Radix Ophiopogonis Extract | Radix Ophiopogonis Extract. Applications: Used for health care products, dietary supplements, herb medecine for heart health. Group: Others. Synonyms: Radix Ophiopogonis Extract; Ophiopogon japonicus(Thunb.). Purity: 5:1 by TLC. Appearance: Brown-yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Ophiopogon japonicus(Thunb.). Radix Ophiopogonis Extract; Ophiopogon japonicus(Thunb.); plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-142. | |
| Radix polygoni multiflori extract | Radix polygoni multiflori extract is prepared from the tuber of prepared Radix Polygoni Multiflori plant (radix polygoni multiflori preparata) that oringinated in China, which latin name is Radix Polygoni Multiflori. Radix polygoni multiflori extract (also known as He shou wu extract, fo ti extract) is a ancient China medical herb that have been used for thousand years, it's commonly used for anti-aging, enhance immunity, hypolipidemic, and anti-atherosclerosis. Group: Others. Radix polygoni multiflori extract; Radix Polygoni Multiflori. Cat No: EXTC-001. | |
| Radix Rehmanniae Extract | Radix Rehmanniae Extract. Applications: Used for women health care products, dietary supplements. Group: Others. Synonyms: Radix Rehmanniae Extract; Rehmannia glutinousa Libosch. Purity: 10:1 By TLC. Appearance: Deep brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Rehmannia glutinousa Libosch. Radix Rehmanniae Extract; Rehmannia glutinousa Libosch.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-095. | |
| Radix Rehmanniae Preparata Extract | Radix Rehmanniae Preparata Extract. Applications: Used for men health care products, dietary supplements, drink additive, for deficiency of liver and kidney. Group: Others. Synonyms: Radix Rehmanniae Preparata Extract; Radix Rehmanniae Preparata. Purity: 5-10:1 by TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Radix Rehmanniae Preparata. Radix Rehmanniae Preparata Extract; Radix Rehmanniae Preparata; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-083. | |
| Radix Saposhnikovia Extract | Radix Saposhnikovia Extract. Applications: Used for women health care products, dietary supplements, treat rheumatism, arthralgia. Group: Others. Synonyms: Radix Saposhnikovia Extract; Saposhnikovia divaricata (Turcz.) Schischk. Purity: 10:1 By TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Saposhnikovia divaricata (Turcz.) Schischk. Radix Saposhnikovia Extract; Saposhnikovia divaricata (Turcz.) Schischk.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-093. | |
| Radotermin | Radotermin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Radotermin. Product Category: Heterocyclic Organic Compound. CAS No. 575458-75-2. Product ID: ACM575458752. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Radotinib | Radotinib(IY-5511) is a novel and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IY-5511. CAS No. 926037-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15728. | |
| Radotinib | Radotinib, also known as IY-5511, is an orally available, hydrochloride salt form of radotinib, a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. The inhibitory effect of radotinib on these specific tyrosine kinases may decrease cellular proliferation and inhibit angiogenesis. This agent has shown potent efficacy in CML cells that are resistant to the first-generation standard tyrosine kinase inhibitors, such as imatinib, nilotinib and dasatinib. PDGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. Check for active clinical trials or closed clinical trials using this agent. Synonyms: IY-5511; IY 5511; IY5511; 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyrazin-2-ylpyrimidin-2-yl)amino]benzamide. Grades: >98%. CAS No. 926037-48-1. Molecular formula: C27H21F3N8O. Mole weight: 530.515. | |
| RAF1 (EE) (306-end), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Raf1 Kinase Inhibitor I - CAS 220904-83-6 | The Raf1 Kinase Inhibitor I, also referenced under CAS 220904-83-6, controls the biological activity of Raf1 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| RAF265 | RAF265 is a potent and orally active RAF/VEGFR2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHIR-265. CAS No. 927880-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10248. | |
| RAF265 | RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Synonyms: CHIR-265; RAF265; CHIR 265; RAF 265; CHIR265; RAF-265. Grades: >98%. CAS No. 927880-90-8. Molecular formula: C24H16F6N6O. Mole weight: 518.41. | |
| RAF 265 | RAF 265. Group: Biochemicals. Alternative Names: CHIR 265; 1-Methyl-5-[[2-[5- (trifluoromethyl) -1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4- (trifluoromethyl) phenyl]-1H-benzimidazol-2-amine. Grades: Highly Purified. CAS No. 927880-90-8. Pack Sizes: 5mg. Molecular Formula: C24H16F6N6O, Molecular Weight: 518.41. US Biological Life Sciences. |  Worldwide |
| RAF-709 | RAF-709 is a novel Raf kinase inhibitor used for the treatment of non-small cell lung cancer (NSCLC). Uses: The treatment of nsclc. Synonyms: N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide; RAF709; RAF-709; RAF 709. Grades: 98%. CAS No. 1628838-42-5. Molecular formula: C28H29F3N4O4. Mole weight: 542.56. | |
| Rafabegron | Rafabegron is a potent and selective beta3-adrenoceptor agonist. Synonyms: 2-[[3-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxy-ethyl]amino]propyl]- 1H-indol-7-yl]oxy]acetic acid; TAK 677; TAK-677; TAK677; AD-9677; AD9677; AD 9677; AJ-9677; AJ-9677; AJ-9677; Rafabegron. Grades: >98%. CAS No. 244081-42-3. Molecular formula: C21H23ClN2O4. Mole weight: 402.875. | |
| Raffinazine impurity 14 | Raffinazine impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1682660-39-4. Molecular formula: C29H33N3O4. Mole weight: 487.6. Catalog: APB1682660394. | |
| Raffinazine impurity 7 | Raffinazine impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108015-71-0. Molecular formula: C8H18N2O. Mole weight: 158.25. Catalog: APB108015710. | |
| Raffinose | Raffinose (Melitose), a non-digestible short-chain oligosaccharide, is a trisaccharide composed of galactose, glucose, and fructose and can be found in many plants. Raffinose (Melitose) can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Melitose. CAS No. 512-69-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N7088. | |
| Raffinose | Raffinose. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Melitriose. Product Category: Heterocyclic Organic Compound. Appearance: Solid. CAS No. 512-69-6. Molecular formula: C18H32O16. Mole weight: 504.44. Purity: 0.98. IUPACName: (2S,3R,4S,5R,6R)-2-[[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. Canonical SMILES: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3(C(C(C(O3)CO)O)O)CO)O)O)O)O)O)O)O. Density: 1.81 g/cm³. Product ID: ACM512696. Alfa Chemistry ISO 9001:2015 Certified. | |
| Raffinose | Raffinose is a white crystalline powder. It is odorless and has a sweet taste approximately 10% that of sucrose. Synonyms: Gossypose; melitose; melitriose; D-raffinose; D-(+)-raffinose. Product ID: PE-0609. Category: Stabilizing Agents. Product Keywords: Other Materials; Stabilizers; PE-0609; Raffinose; Stabilizing Agents;. UNII: N5O3QU595M. Chemical Name: β-D-Fructofuranosyl-O-α-D-galactopyranosyl-(1→6)-α-D-glucopyranoside, anhydrous; β-D-Fructofuranosyl-O-α-D-galactopyranosyl-(1→6)-α-D-glucopyranoside pentahydrate. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Raffinose is stable under ordinary conditions of use and storage.Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide. Source and Preparation: Raffinose occurs naturally in Australian manna, cottonseed meal, and seeds of various food legumes. It can be isolated from beet sugar molasses through sucrose separation, seed-crystallization, and filtration. Applications: Raffinose is a trisaccharide carbohydrate that is used as a bulking agent, blood substitute, stabilizing agent, and water scavenger in freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose solutions. Safety: Raffinose is a naturally occurring trisaccharide investigated for use in freeze-dried pharma |  |
| Raffinose Pentahydrate, Low Glucose (D-(+)-Raffinose, Melitose, Melitriose) | Used as an alternate carbon source for wild-type yeast. Raffinose is a trisaccharide composed of galactose, glucose, and fructose. It can be found in beans, cabbage, brussels sprouts, broccoli, asparagus, other vegetables, and whole grains. Raffinose can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL), an enzyme not found in the human digestive tract. α-GAL also hydrolyzes other α-galactosides such as stachyose, verbascose, and galactinol, if present. The enzyme does not cleave β-linked galactose, as in lactose.The raffinose family of oligosaccharides (RFOs) are alpha-galactosyl derivatives of sucrose, and the most common are the trisaccharide raffinose, the tetrasaccharide stachyose, and the pentasaccharide verbascose. RFOs are almost ubiquitous in the plant kingdom, being found in a large variety of seeds from many different families, and they rank second only to sucrose in abundance as soluble carbohydrates. Group: Biochemicals. Alternative Names: D-(+)-Raffinose; Melitose, Melitriose; O-a-D-Galactopyranosyl-(1->6)-a-D-glucopyranosyl-ß-D-fructofuranoside. Grades: Molecular Biology Grade. CAS No. 17629-30-0. Pack Sizes: 100g, 500g, 1Kg, 2.5Kg, 5Kg. Molecular Formula: C18H32O16 5H2O, Molecular Weight: 594.51. US Biological Life Sciences. | Worldwide |
| raffinose-raffinose α-galactosyltransferase | The 3F position of raffinose can also act as galactosyl acceptor; the enzyme is involved in the accumulation of the tetrasaccharides lychnose and isolychnose in the leaves of Cerastium arvense and other plants of the family Caryophyllaceae during late autumn. Group: Enzymes. Synonyms: raffinose (raffinose donor) galactosyltransferase; raffinose:raffinose α-galactosyltransferase; raffinose-raffinose α-galactotransferase. Enzyme Commission Number: EC 2.4.1.166. CAS No. 93389-38-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2391; raffinose-raffinose α-galactosyltransferase; EC 2.4.1.166; 93389-38-9; raffinose (raffinose donor) galactosyltransferase; raffinose:raffinose α-galactosyltransferase; raffinose-raffinose α-galactotransferase. Cat No: EXWM-2391. | |
| Raffinose-sp-biotin | | |
| Rafigrelide | Rafigrelide is a platelet aggregation inhibitor, which plays a central role in atherothrombotic events. It could prolonge clot formation time and reduce clot strength. Uses: Rafigrelide plays a central role in atherothrombotic events. Synonyms: 6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2(3H)-one;6,7-Dichloro-3,3-dimethyl-5,10-dihydroimidazo[2,1-b]quinazolin-2-one. Grades: >98 %. CAS No. 1029711-88-3. Molecular formula: C12H11Cl2N3O. Mole weight: 284.14. | |
| Rafigrelide | Rafigrelide is a platelet-lowering agent, and also has antithrombotic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,3-Dimethylanagrelide. CAS No. 1029711-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-U00383. | |
| Raf inhibitor 1 | Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093100-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14177. | |
| Raf inhibitor 2 | Raf inhibitor 2 is a potent raf kinase (IC 50 <1.0 μM) inhibitor, compound 32, extracted from patent EP1003721B1. Raf inhibitor 2 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220904-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109574. | |
| Rafivirumab | Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of cocktails. Uses: Designed for use in research and industrial production. Additional or Alternative Names: rafivirumab. Product Category: Inhibitors. CAS No. 944548-37-2. Product ID: ACM944548372. Alfa Chemistry ISO 9001:2015 Certified. | |
| Raf Kinase Inhibitor IV - CAS 303727-31-3 | The Raf Kinase Inhibitor IV, also referenced under CAS 303727-31-3, controls the biological activity of Raf Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Raf Kinase Inhibitor V - CAS 918505-84-7 | The Raf Kinase Inhibitor V, also referenced under CAS 918505-84-7, controls the biological activity of Raf Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Raf Kinase Inhibitor VI - CAS 331444-40-7 | The Raf Kinase Inhibitor VI, also referenced under CAS 331444-40-7, controls the biological activity of Raf Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Rafoxanide | Rafoxanide is a thyroid hormone receptor. Group: Biochemicals. Alternative Names: N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide; 3, 5-Diiodo-3'-chloro-4'- (p-chlorophenoxy) salicylanilide; 3, 5-Diodo-3'-chloro-4'- (p-chlorophenoxy) salicylanilide; 3'-Chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide; 3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide; Disalan; NSC 355278; Ranide. Grades: Highly Purified. CAS No. 22662-39-1. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Rafoxanide | Rafoxanide can be used for the treatment of fasciolasis and fascioliasis in cattle and sheep. Synonyms: Disalan; NSC 355278; BRN 2228187; Ranide; NSC355278; BRN2228187; NSC-355278; BRN-2228187. Grades: >98%. CAS No. 22662-39-1. Molecular formula: C19H11Cl2I2NO3. Mole weight: 626.01. | |
| Rafoxanide | Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein , which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22662-39-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-17598. | |
| Rafoxanide | analytical standard. Group: Pesticides & metabolites standardspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standards. Alternative Names: Benzamide, N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodo-, 3,5-Diodo-3'-chloro-4'-(p-chlorophenoxy)salicylanilide, 3,5-Diiodo-3'-chloro-4'-(p-chlorophenoxy)salicylanilide, Ranide, 3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide, Rafoxanide, Disalan, NSC 355278, Salicylanilide, 3'-chloro-4'-(p-chlorophenoxy)-3,5-diiodo- (8CI), 3'-Chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide. | |
| Rafoxanide-(benzoyl ring-13C6) | analytical standard. Group: Application areas. | |
| RAGE 229 | RAGE 229 is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143072-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147329. | |
| RAGE Antagonist, FPS-ZM1 | A blood-brain-barrier-permeant, non-toxic, tertiary amide compound that acts as a high affinity, potent, multimodal blocker of RAGE (Receptor for Advanced Glycation End products) V domain-mediated ligand binding (Ki = 25, 148, and 230nM, respectively, against Ab40, HMGB1, and S100B, binding to sRAGE). Blocks RAGE-mediated influx of Ab40 and Ab42 into the brain. Also shown to suppress Ab-RAGE induced NF-kB activation and NF-kB-dependent transcription of b-secretase. Daily treatment of APPsw/0 murine AD model (1mg/kg/d via i.p.) is reported to greatly reduce Thioflavin S-positive amyloid plaques in cortex and hippocampus (by 70 to 80%) and restore congnitive performance to the level of non-AD mice.CAS No:945714-67-0. Group: Biochemicals. Grades: Highly Purified. CAS No. 945714-67-0. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| RAGE Antagonist, FPS-ZM1 | RAGE Antagonist, FPS-ZM1, is a blood-brain-barrier permeant blocker of RAGE V domain-mediated ligand binding (Ki = 25, 148, & 230 nM, respectively, against A?40, HMGB1 & S100B, binding to sRAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RAGE antagonist peptide | RAGE antagonist peptide was produced as an inhibitor of the RAGE signaling pathway based on the RAGE-binding domain of high mobility group box-1 (HMGB1). It blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Synonyms: Ac-Glu-Leu-Lys-Val-Leu-Met-Glu-Lys-Glu-Leu-NH2. CAS No. 1092460-91-7. Molecular formula: C57H101N13O17S. Mole weight: 1272.56. | |
| RAGE antagonist peptide | RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1092460-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2268. | |
| RAGE Antagonist Peptide, RAP | The RAGE Antagonist Peptide, RAP controls the biological activity of RAGE. Group: Fluorescence/luminescence spectroscopy. | |
| Rakicidin A | Rakicidin A is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 40 μg/mL. Molecular formula: C32H54N4O7. Mole weight: 606.79. | |
| Rakicidin B | Rakicidin B is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 200 μg/mL. Molecular formula: C33H56N4O7. Mole weight: 620.82. | |
| Ral B human | recombinant, expressed in E. coli, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| rAlbumin human | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Raleukin | Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Kineret; Anakinra. CAS No. 143090-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108841. | |
| Ralfinamide | Ralfinamide (FCE-26742A) is an orally available Na + blocker derived from α-aminoamide, with function of suppressing pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE-26742A. CAS No. 133865-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101437. | |
| Ralfinamide mesylate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ralfinamide mesylate | Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents. It displays analgesic effects in animal models of inflammatory and neuropathic pain. Synonyms: (2S) -2-[[[4-[ (2-Fluorophenyl) methoxy]phenyl]methyl]amino]-propanamide methanesulfonate. Grades: ≥99% by HPLC. CAS No. 202825-45-4. Molecular formula: C17H19FN2O2.CH3SO3H. Mole weight: 398.45. | |
| Ralfinamide Mesylate | Ralfinamide Mesylate. Group: Biochemicals. Alternative Names: (2S) -2- [ [ [4- [ (2-Fluorophenyl) methoxy] phenyl] methyl] amino] propanamide Methanesulfonate; (S)-Monomethanesulfonate; (S) -2- [ [4- [ (2-Fluorobenzyl) oxy] benzyl] amino] propanamide Methanesulfonate. Grades: Highly Purified. CAS No. 202825-45-4. Pack Sizes: 25mg. Molecular Formula: C18H23FN2O5S, Molecular Weight: 398.45. US Biological Life Sciences. | Worldwide |
| Ralimetinib dimesylate | Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK ?/? with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2228820 dimesylate. CAS No. 862507-23-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13241. | |
| Ralinepag | Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC 50 s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD811. CAS No. 1187856-49-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16751. | |
| Ralinepag | This active molecular is a Epoprostenol receptor agonist which is an investigational drug candidate developed by Arena and intended for the treatment of vasospastic diseases, for an example, Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin which elicits a potent vasodilation and inhibits platelet aggregation when binding to this receptor. In Jan 2015, Phase-II clinical trials in Pulmonary arterial hypertension in USA was on going. In Jul 2015, Phase-II clinical trials in Pulmonary arterial hypertension in Spain was on going. In Jul 2015, Arena initiated enrolment in a phase II extension trial for Pulmonary arterial hypertension in USA, Czech Republic, Hungary, Poland. Uses: Pulmonary arterial hypertension. Synonyms: 2- [ [4- [ [ (4-chlorophenyl) -phenylcarbamoyl] oxymethyl] cyclohexyl] methoxy] acetic acid,APD-811; APD 811; APD811; Ralinepag. Grades: 98%. CAS No. 1187856-49-0. Molecular formula: C23H26ClNO5. Mole weight: 431.91. | |
| Ralmitaront | Ralmitaront Inhibitor. Uses: Scientific use. Product Category: T9183. CAS No. 2133417-13-5. |  |
| Ralometostat | TNG908 is a MTAP synergistic PRMT5 inhibitor. TNG908 crosses the blood-brain barrier and is orally active. TNG908 could be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNG908. CAS No. 2760481-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148419. | |
| Raloxifene | Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Keoxifene; LY156758 free base; LY139481. CAS No. 84449-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13738. | |
| Raloxifene-4',6-Diglucuronide Lithium Salt | A metabolite of Raloxifene.Raloxifene is selective estrogen receptor modulator. It can be used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast. Grades: > 95%. Molecular formula: C40H41NO16S. 2 Li. Mole weight: 837.71. | |
| Raloxifene 4-β-D-Glucuronide Lithium Salt | | |
| Raloxifene 4-D-glucuronide D4 | Raloxifene 4-D-glucuronide D4 is a formidable metabolite derived from Raloxifene, renowned for its usage in studying osteoporosis within postmenopausal women. Molecular formula: C34H31NO10SD4. Mole weight: 653.73. | |
| Raloxifene-4-D-glucuronide D4 lithium salt | Raloxifene-4-D-glucuronide D4 lithium salt is a notable biomedical compound, aiding in studying postmenopausal osteoporosand breast cancer. Operating as a discerning estrogen receptor modulator, this stable derivative of Raloxifene showcases enhanced solubility and bioavailability conferred by its salt form. Molecular formula: C34H30NO10SD4 Li. Mole weight: 659.66. | |
| Raloxifene-4-D-glucuronide lithium salt | Raloxifene-4-D-glucuronide lithium salt is an esteemed biomedical compound, ingeniously deployed for studying the ravages of osteoporosand curbing the sinister growth of breast cancer. This prodigious innovation is a cleverly modified iteration of raloxifene, an acclaimed selective estrogen receptor modulator (SERM). Molecular formula: C34H34NO10S Li. Mole weight: 655.64. | |
| Raloxifene-4'-D-glucuronide lithium salt | Raloxifene-4'-D-glucuronide lithium salt is a biomedical product used in the research of osteoporosand breast cancer. This compound, containing Raloxifene and lithium, has potential estrogen agonist/antagonist activity, enabling it to selectively modulate estrogen receptors. Its glucuronide form enhances its solubility and bioavailability. Synonyms: Raloxifene 4'-Glucuronide; 182507-22-8; Raloxifene-4-glucuronide; UNII-UZ95WFT3LZ; UZ95WFT3LZ; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[4-[6-hydroxy-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-2-yl]phenoxy]oxane-2-carboxylic acid; beta-D-Glucopyranosiduronic acid, 4- (6-hydroxy-3- (4- (2- (1-piperidinyl)ethoxy)benzoyl)benzo (b)thien-2-yl)phenyl; beta-D-Glucopyranosiduronic acid, 4-[6-hydroxy-3-[4-[2- (1-piperidinyl) ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl; CHEMBL176790; DTXSID601312492; AKOS040736548; Raloxifene-4'-D-glucuronide lithium salt; HY-135582; CS-0113549; Q27291346; (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)benzoyl)benzo[b]thiophen-2-yl)phenoxy)tetrahydro-2H-pyran-2-carboxylic acid.BETA.-D-GLUCOPYRANOSIDURONIC ACID, 4- (6-HYDROXY-3- (4- (2- (1-PIPERIDINYL)ETHOXY)BENZOYL)BENZO (B)THIEN-2-YL)PHENYL. Molecular formula: C34H35NO10S·xLi. Mole weight: 649.71 (free acid). | |
| Raloxifene-4' -glucuronide | A metabolite of Raloxifene. Raloxifene is selective estrogen receptor modulator. It can be used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast. Synonyms: 4-[6-Hydroxy-3-[4-2[2- (1-piperindinyl) ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic acid. Grades: > 95%. CAS No. 182507-22-8. Molecular formula: C34H35NO10S. Mole weight: 649.71. | |
| Raloxifene 4-Monomethyl Ether | Raloxifene 4-Monomethyl Ether. Group: Biochemicals. Alternative Names: [6-Hydroxy-2- (4-methoxyphenyl) benzo [b] thien-3-yl] [4- [2- (1-piperidinyl) ethoxy] phenyl] methanone. Grades: Highly Purified. CAS No. 185415-07-0. Pack Sizes: 10mg. Molecular Formula: C29H29NO4S, Molecular Weight: 487.61. US Biological Life Sciences. | Worldwide |
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