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| Product | Description | |
|---|---|---|
| Soy Extract Polar | Soy Extract Polar. Alternative Names: Soybean Polar Lipid Extract. CAS No. 8030-76-0. Product ID: ALCFA8030760. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Soy Furanone | Soy Furanone (Ethyl-2 5-Methyl 4-Hydroxy 3(2H)-Furanone). CAS No. 27538-09-6. FEMA No. 3623. Kosher: Y. VIGON Item # 501380. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Soy Isoflavones | Soy Isoflavones. Alternative Names: Isoflavone. Purity: 0.98. Product ID: CI-OT-0093. Molecular formula: C15H10O2. Mole weight: 222.24 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Soy Lecithin Powder 20% PhosphatidylCholine | Soy Lecithin Powder 20% PhosphatidylCholine. |  CA, FL & NJ |
| Soy PA | Phosphatidic acid is a simple and basic glycerophospholipid. It is an ester of glycerol with two long-chain fatty acids at C1 and C2 positions and phosphoric acid at the C3 positions. Alternative Names: L-α-phosphatidic acid (Soy) (sodium salt). Grades: 98%. CAS No. 475995-54-1. Molecular formula: C37H68NaO8P. Mole weight: 694.89. |  |
| Soy PC | INCI: Phosphatidylcholine, Carthamus tinctorius (Safflower) Seed Oil, Glycerin, Caprylic / Capric Tryglyceride, Alcohol, Glyceryl Stearate, Soy Acid, Ascorbyl Palmitate, Tocopherol Fluidlecithin Super is a natural emulsifier made from 50% high-quality choline phospholipid and 50% safflower oil. It can be used to produce cold- and warm-stirred emulsions. Fluidlecithin Super is used as a refatting agent in shower gels and as a co-emulsifier in creams and is particularly suitable for dry, sensitive skin and skin in need of care. Fluidlecithin Super is light yellow in colour and has little odour of its own. The finished emulsions are white in colour. Fluidlecithin Super can be processed both hot and cold; subsequent dosing is also possible. Emulsions made with Fluidlecithin Super should be dispersed at high speed to improve the feel of the emulsion. When used as the sole emulsifier, a consistency enhancer and/or gelling agent should be used for stabilisation. Uses: Body care face care. Alternative Names: L-α-phosphatidylcholine (Soy); PC (soybean); Soya Phosphatidylcholines. Grades: >99%. CAS No. 97281-47-5. Molecular formula: C42H80NO8P. Mole weight: 758.06. | |
| Soy PC (20%) | Soy PC (20%). Group: Others. L-α-phosphatidylcholine, 20% (Soy) (Soy Total Lipid Extract); Soy PC (20%). Cat No: PHOZ-247. |  |
| Soy PC (40%) | Soy PC (40%). Group: Others. L-α-phosphatidylcholine (Soy-40%); Soy PC (40%). Cat No: PHOZ-246. | |
| Soy PG | Soy PG is a phosphatidylglycerol (PG) mixture containing greater proportion of polyunsaturated fatty acids. Alternative Names: 16:0-18:2 PG; PG (Soybean); Soybean Phosphatidylglycerol; L-α-phosphatidylglycerol (soybean). Grades: >98%. CAS No. 322647-44-9. Molecular formula: C40H74NaO10P. Mole weight: 769. | |
| Soy protein | Soy protein is a protein that is isolated from soybean. Soya protein is made from soybean meal that has been dehulled and defatted. Dehulled and defatted soybeans are processed into three kinds of high protein commercial products.Soy protein is a vegetable protein. Amino acid composition of soybean protein and milk protein is similar, in addition to methionine slightly lower, the rest of the essential amino acid content are more abundant, is a plant of the full protein, in nutritional value, can be equated with animal protein, the gene structure is also the most close to human amino acids, so it is the most nutritious vegetable protein. Applications: 1. it can be used to raise the yield of meat products.2. it can be added to such solid drinks as oatmeal, coffee mate, soy milk powder peanut milk powder, cocoa milk powder, walnut milk powder, fermented yogurt, juice milk powder, etc. 3. it can also be added to cold drinks (such as ice cream) to reduce the production costs. Group: Others. Appearance: Light yellow powder. Soy protein. Cat No: EXTC-218. | |
| Soy Protein Isolate Food Grade | Soy Protein Isolate Food Grade. | CA, FL & NJ |
| Soy Trimethouysilylpropyldimonium Chloride | Soy Trimethouysilylpropyldimonium Chloride (STMS) is a chemical compound derived from soybeans. It is commonly used in hair care products such as shampoos, conditioners, and hair treatments. STMS is a quaternary ammonium compound, meaning it has a positively charged nitrogen atom that helps it to bond to hair or skin. It is often used in hair care products because it can help to detangle hair and make it feel smoother and more manageable. In addition to its conditioning properties, STMS can also help to reduce static electricity in hair, which can make it easier to style. It is also a mild antistatic agent, and can help to reduce frizzy and flyaway hair. Product ID: CI-HC-0074. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SP 100030 | SP 100030 is a potent dual inhibitor of NF-κB and AP-1 transcriptional activity (IC50 = 50 nM). SP 100030 blocks production of IL-2, IL-8 and TNF-α from Jurkat T cells. It inhibits cytokine production selectively in T cells and exhibits minimal inhibitory effects on cytokine production in other cell types. Alternative Names: SP-100030; SP 100030; SP100030; N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide. Grades: ≥98%. CAS No. 154563-54-9. Molecular formula: C14H5ClF9N3O. Mole weight: 437.65. | |
| SP 100030 | SP 100030. Group: Biochemicals. Grades: Purified. CAS No. 154563-54-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SP-100030 | SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154563-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110177. |  |
| SP11 | SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinsons disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2629218-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172942. | |
| SP 141 | SP 141. Group: Biochemicals. Grades: Purified. CAS No. 1253491-42-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SP-141 | SP-141 is a specific inhibitor of MDM2. SP-141 promotes MDM2 auto-ubiquitination and degradation. SP-141 might be used for the research of pancreatic cancer and breast cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1253491-42-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110182. | |
| SP187 | SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MON-DNJ; UV4. CAS No. 615253-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00160. | |
| Sp-2',3'-cAMPS | Sp-2',3'-cAMPS is a crucial cyclic nucleotide analog acting as an activator of protein kinase A (PKA), enabling the study of its role in signal transduction pathways. This product is widely used in biomedical field research to investigate the modulation of PKA activity and its implications in various drug responses and diseases involving cAMP-dependent signaling pathways. Alternative Names: Adenosine- 2', 3'- cyclic monophosphorothioate, exo / Sp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 118276-00-9. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3. | |
| SP2509 | SP2509 is a potent and selective antagonist of lysine specific demethylase 1 (LSD1) with an IC50 of 13 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1423715-09-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12635. | |
| SP27 | SP27 is a PROTAC that can selective degrades PLK4, with a DC50 of 19.5 nM. SP27 can be used for the research of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034805-75-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149324. | |
| Sp-2-AEA-cAMPS | Sp-2-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Alternative Names: 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-2-AEA-cAMPS-Agarose | Sp-2-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 2- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose. | |
| Sp-2'-AEC-cAMPS | Sp-2'-AEC-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Alternative Names: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C13H18N7O6PS. Mole weight: 431.4. | |
| Sp-2'-AEC-cAMPS-Agarose | Sp-2'-AEC-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-2-AHA-cAMPS | Sp-2-AHA-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. It is also a PDE-resistant analogue of 2-AHA-cAMP. Alternative Names: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214276-94-5. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-2-AHA-cAMPS-Agarose | Sp-2-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 2- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cAMPS | Sp-2'-AHC-cAMPS is a PDE-stable analogue of cAMP used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Alternative Names: 2'- (6- Aminohexyl)carbamoyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O6PS. Mole weight: 487.5. | |
| Sp-2'-AHC-cAMPS-Agarose | Sp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2'-AHC-cGMPS | Sp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Alternative Names: 2'- (6- Aminohexyl)carbamoylguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 1262749-61-0. Molecular formula: C17H26N7O7PS. Mole weight: 503.5. | |
| Sp-2'-AHC-cGMPS-Agarose | Sp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-2-CF3-cBIMPS | Sp-2-CF3-cBIMPS, a research chemical focused on insulin and glucose metabolism, has potential therapeutic benefits for metabolic diseases like diabetes. By activating the AMP-activated protein kinase (AMPK) pathway, it shows that adding a trifluoromethyl group can increase its potency compared to other AMPK activators. With its documented scientific profile, Sp-2-CF3-cBIMPS embodies a unique approach to metabolism research to inspire medical advancements. Alternative Names: 2- Trifluoromethyl- 1- β- D- ribofuranosylbenzimidazole- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Molecular formula: C13H11F3N2O5PS · Na. Mole weight: 418.3. | |
| Sp-2-Cl-cAMPS | Sp-2-Cl-cAMPS is an analogue of Sp-cAMPS, the protein kinase A stimulator. The chlorine atom in position 2 of adenine nucleobase significantly increase the stability and lipophilicity. Alternative Names: 2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124854-63-3. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-2'-O-MB-cAMPS | Sp-2'-O-MB-cAMPS is a precursor ofSp-cAMPS, a PDE-resistant stimulator of protein kinase A. Sp-cAMPS and butyrate are released after the metabolism of Sp-2'-O-MB-cAMPS by esterases. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Alternative Names: 2'- O- Monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 152218-23-0. Molecular formula: C14H17N5O6PS · Na. Mole weight: 437.4. | |
| Sp-2'-O-Me-CTP-α-S | Sp-2'-O-Me-CTP-α-S is a CTP analogue that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Alternative Names: 2'- O- Methylcytidine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-01-0. Molecular formula: C10H18N3O13P3S (free acid). Mole weight: 513.3 (free acid). | |
| Sp-2'-O-Me-GTP-α-S | Sp-2'-O-Me-GTP-α-S is an analogue of GTP that can be used for enzymatic introduction of phosphorothioate and modified 2'-OH groups into RNA. Alternative Names: 2'- O- Methylguanosine- 5'- O- (1- thiotriphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143029-02-1. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
| Sp-5,6-DCl-cBIMPS | Sp-5,6-DCl-cBIMPS is a selective stimulator of cAMP- dependent protein kinases preferrring site B of type II isozyme. It is superior to dibutyryl cAMP or 8-CPT-cAMP in stability, membrane permeability and potency. Alternative Names: 5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 120912-54-1. Molecular formula: C12H10Cl2N2O5PS · Na. Mole weight: 419.2. | |
| SP600125 | SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129-56-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12041. | |
| SP600125 | SP600125 (Nsc75890) is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc. SP600125 is also a broad?spectrum inhibitor of serine / threonine kinases including Aurora kinase A, FLT3 and TRKA with of IC50 of 60?nM, 90?nM and 70?nM. SP600125 inhibits autophagy and activates apoptosis. Group: Inhibitors. Alternative Names: Nsc75890. CAS No. 129-56-6. Pack Sizes: 10mg. Product ID: S1460. Formula: C14H8N2O. Smiles: C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| SP 600125 | SP 600125. Group: Biochemicals. Grades: Purified. CAS No. 129-56-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sp-6-AE-cAMPS | Sp-6-AE-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C12H17N6O5PS. Mole weight: 388.4. | |
| Sp-6-AE-cAMPS-Agarose | Sp-6-AE-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-AH-cAMPS | Sp-6-AH-cAMPS is a phosphodiesterase-resistant ligand in affinity chromatography of cAMP and cGMP binding proteins and can be modified with fluorophores and other markers. Grades: ≥ 98% by HPLC. Molecular formula: C16H25N6O5PS. Mole weight: 444.5. | |
| Sp-6-AH-cAMPS-Agarose | Sp-6-AH-cAMPS-Agarose is the Sp-cAMPS immobilized on agarose by an aminohexyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. | |
| Sp-6-Bnz-cAMPS | Sp-6-Bnz-cAMPS is a selective and PDE-resistant stimulator of cAMP-dependent protein kinase, which can be used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 152218-18-3. Molecular formula: C17H15N5O6PS · Na. Mole weight: 471.4. | |
| Sp-6-Cl-cPuMPS | Sp-6-Cl-cPuMPS is a PDE-resistant activator of protein kinase A that can be modified in position 6. Alternative Names: 6- Chloropurine riboside- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 129693-12-5. Molecular formula: C10H9ClN4O5PS · Na. Mole weight: 386.7. | |
| Sp-6-Phe-cAMPS | Sp-6-Phe-cAMPS is a selective and PDE-resistant stimulator of protein kinase A, which is used as an Epac-negative control. Grades: ≥ 98% by HPLC. CAS No. 169335-92-6. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4. | |
| Sp-8-AEA-cAMPS | Sp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Alternative Names: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-84-3. Molecular formula: C12H18N7O5PS. Mole weight: 403.4. | |
| Sp-8-AEA-cAMPS-Agarose | Sp-8-AEA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel. | |
| Sp-8-AET-cGMPS | Sp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-92-3. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4. | |
| Sp-8-AET-cGMPS-Agarose | Sp-8-AET-cGMPS-Agarose is the protein kinase G activator Sp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-AHA-cAMPS | Sp-8-AHA-cAMPS is a PDE-stable cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 8-AHA-cAMP. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-03-4. Molecular formula: C16H26N7O5PS. Mole weight: 459.5. | |
| Sp-8-AHA-cAMPS-Agarose | Sp-8-AHA-cAMPS-Agarose is the protein kinase A activator Sp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel. | |
| Sp-8-BnT-2'-O-Me-cAMPS / "S-223" | Sp-8-BnT-2'-O-Me-cAMPS is the most potent 2'-substituted activator of Epac2. In human osteosarcoma U2OS cell lines expressing Epac1 or Epac2, Sp-8-BnT-2'-O-Me-cAMPS does not induce Epac signalling at 100 μM possibly for inefficient cellular uptake in this biosystem. Alternative Names: 8- Benzylthio- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C18H19N5O5PS2 · Na. Mole weight: 503.5. | |
| Sp-8-BnT-cAMPS / "S-220" | Sp-8-BnT-cAMPS is an exceptional stimulant targeting protein kinase A (PKA) with remarkable precision. While S-220 is an exquisite synthetic compound with antimicrobial prowess. Alternative Names: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. Molecular formula: C17H17N5O5PS2 · Na. Mole weight: 489.5. | |
| Sp-8-Br-2'-O-Me-cAMPS | Sp-8-Br-2'-O-Me-cAMPS is a anti-hydrolytic form of 8-Br-2'-O-Me-cAMP, a specific membrane-permeant stimulator of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Alternative Names: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-34-7. Molecular formula: C11H12BrN5O5PS · Na. Mole weight: 460.2. | |
| Sp-8-Br-cAMPS | Sp-8-Br-cAMPS is a resistant activator of protein kinase A, the cAMP agonist. Compared to Sp-cAMPS, it has more lipophilic and membrane-permeant properties. Alternative Names: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 127634-20-2. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2. | |
| Sp-8-Br-cAMPS-AM | Sp-8-Br-cAMPS-AM is a PDE-resistant precursor of Sp-8-Br-cAMPS, the protein kinase A stimulator. The active analogue is released after the metabolism of Sp-8-Br-cAMPS-AM by esterases. Alternative Names: 8- Bromoadenosine- 3', 5'- monophosphorothioate, acetoxymethyl ester, Sp- isomer ( Sp-8-Br-cAMPS-AM ). Grades: ≥ 97% by HPLC for mixture of the axial and equatorial isomer. Molecular formula: C13H15BrN5O7PS. Mole weight: 496.2. | |
| Sp-8-Br-cGMPS | Sp-8-Br-cGMPS is an activator of protein kinase G I α and protein kinase A. It has a resistant effect against cyclic nucleotide phosphodiesterases. Compared to cGMP or Sp-cGMPS, it has more lipophilic and membrane-permeant properties. Alternative Names: 8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-03-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2. | |
| Sp-8-Br-PET-cGMPS | Sp-8-Br-PET-cGMPS is an inhibitor of the retinal type cGMP-gated ion channel (cGMP antagonist) as well as a stimulator of cyclic GMP-dependent protein kinase I α and I ß (cGMP agonist), which is used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-21-2. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3. | |
| Sp-8-Cl-cAMPS | Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant properties. Alternative Names: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Sp- isomer. Grades: ≥ 99% by HPLC. CAS No. 142754-28-7. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-8-CPT-cAMPS | Sp-8-CPT-cAMPS is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129693-13-6. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8. | |
| Sp-8-OH-cAMPS | Sp-8-OH-cAMPS is a polar analogue of Sp-cAMPS, the protein kinase A activator, with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. It can be used for the study of extracellular cAMP receptors. Alternative Names: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 749843-87-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3. | |
| Sp-8-pCPT-2'-O-Me-cAMPS | Sp-8-pCPT-2'-O-Me-cAMPS is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which is inactive for protein kinase A. It is much more lipophilic and membrane permeant. Alternative Names: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 634208-37-0. Molecular formula: C17H16ClN5O5PS2 · Na. Mole weight: 523.9. | |
| Sp-8-pCPT-cGMPS | Sp-8-pCPT-cGMPS is a stimulator of protein kinase G type I α and type II with superior membrane permeability and stability. Uses: Enzyme inhibitors. Alternative Names: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 160385-87-5. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9. | |
| Sp-8-pCPT-PET-cGMPS | Sp-8-pCPT-PET-cGMPS is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Sp-8-Br-PET-cGMPS, Sp-8-pCPT-PET-cGMPS is much more lipophilic and membrane-permeant. Alternative Names: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-63-2. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626. | |
| Sp-8-PIP-cAMPS | Sp-8-PIP-cAMPS is a selective cAMP analogue with a preference for site B of protein kinase A type II. Alternative Names: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 156816-35-2. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4. | |
| SP-96 | SP-96 is a highly potent, selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2682114-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131339. | |
| SPA0355 | SPA0355 is a thiourea derivative that has antioxidant and anti-inflammatory properties. SPA0355 inhibits the RANKL (receptor activator of nuclear factor κB ligand) induced osteoclast formation in primary bone marrow-derived macrophages. SPA0355 also suppresses the activation of the MAPKs, Akt, and NF-κB pathways. Additionally, SPA0355 promotes osteoblast differentiation, increases alkaline phosphatase activity, and enhances mineral nodule formation. SPA0355 can protect ovariectomized mice from bone loss by stimulating osteoblast differentiation and inhibiting osteoclast resorption, making it useful for studying postmenopausal osteoporosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1251839-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169703. | |
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